Can L-Leucine Help Glucose Metabolism And Insulin Function?
June 02, 2014 08:54 AM
What is a leucine
Leucine is one of 3 amino acids that increases muscle mass and will also help you to recover after exercise. Leucine supplies the body with energy and regulate blood sugar. Being an essential amino acids, it cannot be synthesized by the body and thus you need to get it from food or supplements. But Can L-Leucine help glucose metabolism and insulin function?
What does leucine do
L-leucine has direct bearing on the amount of insulin produced. L-leucine will stimulate the amount of insulin produced by the pancreas. One of the ways in which it influences the amount of insulin produced is by enhancing glutaminolysis by allosterically activating GDH (glutamate dehydrogenase).
Benefits of leucine
Increased insulin levels have a major implications on glucose metabolism. Increased insulin level will directly result into faster glucose absorption into the blood stream. Increased glucose metabolism prevents the body from using lean muscles to supply energy during workouts. Unlike isoleucine and valine, L-leucine are converted to glucose slowly and thus you can have sustained energy for long.
It is also very effective in muscle building. By stimulating insulin release and glucose metabolism, it enables key nutrients such as amino acids, Creatine and glucose to enter muscle cells. Since insulin will stimulate rapid muscle synthesis while inhibiting protein breakdown, L-leucine will build lean muscle mass with a short period.
L-leucine is alternative to Steroids, it is safer and its effects are lasting. During workouts, it supports oxidative metabolism in muscles and decrease protein degradation.
If you are looking for the best way you can build muscle mass and strength without adverse effects, L-leucine is premier supplement. Apart from building muscle, l-leucine will also improve brain functions. You can take more workouts. L-leusine supplement has been used by many body builders and has been proved beyond doubt to be effective supplement. If you have been wondering if l-leucine help glucose metabolism and insulin function, no doubt it is can.
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Can Guggle Extract Improve Bile And Fat Metabolism?
May 05, 2014 08:13 PM
Guggul extract on weight loss
It is good to maintain a healthy lifestyle. If you do not do so, falling prey to a number of health complications is inevitable. Among the causes of these complications, fats metabolism happens to play a big part. There are numerous ways to help deal with problems associated with fat metabolism; guggle extract is one of them. A plant found in Asia and North African parts is widely used in weight loss programs. Its bark contains some sap that is extracted to offer the desired product. Many people are asking questions on how this extract helps improve both bile and fat metabolism.
How effective guggul extract
The sap obtained is also referred to us gum guggle or rather guggglesterones. These plant Steroids are responsible for the positive effects the herb on the body fat metabolism. How does it help reduce cholesterol? It simply prompts an increase in the functioning of the thyroid. Biologically, this helps enhance metabolism. It occurs because food digestion is improved while at the same time the conversion of carbohydrates to fats is inhibited thus reducing cholesterol levels in blood. Perhaps that is why it is used in most weight loss programs.
Other health benefits of guggle extract
Furthermore, guggle extract improves bile functioning due to its cholesterol reduction characteristics. It kills two birds with one stone. As seen earlier, it inhibits formation of cholesterol on blood. Second, it helps in the excretion cholesterol from the body system. It is able to do this effectively due to the presence of phytochemicals. They inhibit farnesoid X receptor, which happens to be the bile acid receptor responsible for cholesterol levels in the body. It even blocks oxidation of low-density lipo-proteins thus enabling the breakdown of cholesterol into manageable compounds.
Finally, there is no doubt on if guggle extracts helps improve bile and fat metabolism. There may be a few people who question its effectiveness, but numerous studies have cemented the truthfulness of the idea. This herb also has other uses thus check out for our next article to understand more about it.
What Are The Health Benefits Of Borage Seed Oil?
December 29, 2013 05:21 PM
What is Borage
The borage also known as starflower plant generates seeds enriched with essential fatty acid known as Gamma-linolenic acid. In ancient times, borage plant was mainly used to prepare salad and soups due to its relaxing effect on people. However, in modern times people are more interested in borage seeds. This is due to its health benefits offered by gamma-linolenci acid (GLA). GLA has anti-inflammatory effects useful to both men and women. Borage oil comprises about 24% of GLA which is the highest known energy for naturally occurring GLA. After consumption, much of the GLA found in borage oil turns into dihomo-gamma-linolenic acid. GLA and DGLA prevent inflammation just like omega-3-fatty acids from fish oil or flaxseed. However, GLA and DGLA are categorized as omega-6-fatty acids.
According to recent studies, Borage oil can be used to treat rheumatoid arthritis. This is an autoimmune ailment which results to joint lining inflammation. Rheumatoid arthritis is a chronic and painful ailment that requires use of non-Steroidal anti-inflammatory medications, such as, NSAIDS that can have side effects. Borage oil is used to reduce tenderness and swelling for rheumatoid arthritis patients.
If you plan to use borage oil for treating any health problem, ensure that you consult your doctor before you begin using your supplement treatment.
What Are The Benefits Of Turmeric Extract?
June 04, 2013 01:53 PM
Turmeric extract, also known as Curcuma longa has been used for over 4000 years to treat a variety of conditions. Reputable studies show that it may help control infections, reduce inflammation, and treat digestive problems and some cancers. Historically, it has been widely used in cooking Indian dishes and is much loved due to its curry flavor and yellow color.
Further, it's used to color butter and cheese and has been intensively applied in both Chinese and Ayurvedic medicine to treat wounds and skin diseases.
According to research done at the University of Maryland Medical Center, turmeric extract contains powerful ingredients that stimulate the production of bile and thus can be used to control indigestion.
Let us take a more straight forward look at its main benefits to human health.
Benefits of Turmeric Extract
* Fighting inflammation
Turmeric contains a special substance called curcumin which aside from destroying free radicals lowers the levels of some enzymes in the body that fuel inflammation. Clinical studies have suggested that turmeric's duo benefits (antioxidant and anti-inflammatory) are an essential part of recovering from joint stiffness - useful in relieving rheumatoid arthritis.
As we mentioned earlier, turmeric can boost the production of bile. One double-blind study (done by The German Commission E) concluded that turmeric may help in improving the functioning of the digestive system by reducing bloating.
* Turmeric and ulcerative colitis
Although turmeric does not seem to help control stomach ulcers, researchers at the University of Maryland Medical Center confirm that can play a central role in people with ulcerative colitis by helping them stay in remission. Recent studies done on people with this disease (who consumed turmeric) showed a lower relapse rate than who took other treatment substances.
* Turmeric extract and cancer
Though most results are still early, there has been a great deal of findings that have painted turmeric in good light as far as treatment of various cancers is concerned. At the moment, scientists are keenly studying its effects on colon, skin, breast and prostate cancers. All the same, turmeric is known for its preventive effects which have something to do with its strong antioxidant properties.
* Turmeric=Good Heart Health
Some substances found in turmeric extract may help reduce incidences of atherosclerosis - a condition closely associated with the occurrence of stroke and/or heart attack. It, in a great way lowers cholesterol levels in blood vessels. Aside from that, it stops platelets from clumping together thus preventing blood clots from accumulating along blood vessels.
* Containing Viral and Bacterial Infections
Turmeric may to some extent kill viruses and bacteria. Some of its active ingredients are as well known to expel intestinal worms.
Turmeric has been for a long time been associated with good eye health. Well, researchers have recently made breakthrough findings that curcumin (turmeric's main active ingredient) may help treat chronic anterior uveitis. Its efficiency is believed to be at par with corticoSteroids.
There are many other health benefits associated with turmeric extract. However, the few mentioned herein are the most important ones that you need to take note of.
Benefits of Extended Release Guggulipid
January 03, 2013 04:10 PM
Guggul is one of the holistic ancient herbal extracts derived from the Commiphora wightii plant that had been predominant in India although some parts of northern Africa and Asia still had some traces of the same. Over the years, Guggul resin gum derived from the plant has been used to promote a healthy living, and has a good number of recent scientific research findings to back it up. Some of the health benefits associated with the use of Guggulipids supplements (also known as the Guggulsterone Supplements) include lowering of Low Density Lipoproteins (Bad Cholesterol), reducing inflammation, and significantly lowering the risk of suffering from cardiovascular diseases, tumors and cancers.
Extensive scientific research shows that Guggulipids play an important role in inhibition of its synthesis in the liver and its hydrolysis into bile salts. It also acts on the thyroid gland which in turn controls the Basal Metabolic Rate that directly relates to the rate of cholesterol catabolism in the body. Additionally, a cascade of reactions in the liver during the process of cholesterol hydrolysis down-regulates the uptake of cholesterol in the gut which ensures that the body is at a healthy blood cholesterol level.
The anti-inflammatory, anti-tumor and anti-cancer effects are highly associated with the stimulation of the liver to release C-Reactive Protein. Even though the CRP protein is primarily produced by the body in response to inflammation and cell death, presence of the CRP in the blood stream prior to an acute inflammation or cell death plays an important role in toning down inflammatory conditions such as rheumatoid inflammation as well as killing abnormal cells before they develop into tumors and cancerous cells.
However, Guggulsterones are rapidly regenerated in the body in the same rate that other Steroid hormones are degenerated which makes the use of extended release Guggulipid supplements very essential. This makes it possible to have the body under constant supply of the component for optimal guggulsterone health benefits.
Korean Ginseng Root Extract
December 14, 2012 12:28 PM
Korean ginseng is a perennial herb that has been long renowned for its medicinal properties in curing various health disorders. Extracts of the root of this plant are made by dilution of one part of ginseng root with one part of water and alcohol.
The Korean ginseng root has been a staple ingredient in traditional Chinese medicines for more than 2000 years. This herb was considered a miracle drug by them, and the theory of its beneficial properties has been passed down through the ages. People still recognize the miraculous powers of this root, and use it as a natural antidote for various ailments. The ginseng root is generally, powdered only after six years of its growth and is made available in the form of extracts at stores all over the world. The Korean root is believed to comprise of various phytochemicals which are the main cause of all beneficial properties.
Benefits of Korean ginseng root extract
General health tonic
Ginseng is classified as an adaptogen, which acts as a complete health tonic. This extract can help the body rebound from fatigue, arising from various kinds of stress. It also aids in improving energy and physical endurance, thereby, contributing to the overall well-being of an individual.
Improves cardiovascular function
- This root extract can prevent organ and tissue prolapse, and improve blood circulation for improved cardiovascular function. It lowers the bad cholesterol levels and increases HDL cholesterol in the human body.
Improves functioning of the nervous system
The plant nutrients found in the herb extract can enhance the cognitive abilities and act as memory boosters. They can cure problems related to poor concentration, memory, insomnia and anxiety.
The ginseng extract holds great promises for people with type-2 diabetes as it can result in greater glucose and insulin resistance.
Ginseng extract has also been proved to act as a preventive remedy for several kinds of cancer.
The extracts of this herb act as a stimulant for boosting the immunity and effectively prevent all kinds of flu and cold.
Korean ginseng root extract has worked miracles on improving the general well-being of a person. The numerous benefits of ginseng extract might seem compelling but it is advisable to exercise caution, as with other herbal supplements. Consult your physician before consuming ginseng to explore probable side-effects with existing medication.
What Are The Health Benefits Of DMAE?
April 26, 2012 12:57 PM
Dimethylaminoethanol or DMAE is anorganic compound that is metabolically produced by the adrenal glands, testes and the brain in small quantities. It is converted into testosterone, estrogen and cortisone by the body. It is a known fact that the liver processes DMAE into choline, but the molecule thus produced is charged and cannot break the blood-brain barrier. Studies have shown that DMAE methylated in the brain acts as the precursor for the manufacture of acetylcholine, a neurotransmitter that plays a key role in the conduction of signals in the brain as well as the nervous system.
DMAE also stimulates phosphatidylcholine, a crucial part of cell membranes. However, the DMAE naturally produced by the body is sufficient only to maintain healthy brain and functions. It will not improve their functions. Though DMAE is found in fish such as salmon, anchovies, and sardines, supplementation in the pill form is important because of the practical difficulties having these foods in the right form and quantity on a daily basis to derive the benefits. DMAE supplements for oral consumption are through stores that sell health foods and groceries.
Daily consumption of DMAE in the supplement form provides a number of benefits to the body. Some of the benefits are as follows:
It helps prevent as well as treat cardiovascular problems and boost the body's immune system because of its strong antioxidant properties.It protects cells from the harmful effects of free-radicals by helping them retain the nutrients that are essential and expelling waste.As a precursor in the production of the neurotransmitter acetylcholine, it supports the functioning of the brain in a number of ways. It increases a person's attention span, relieves behavioral problems and hyperactivity or attention deficit hyperactivity disorder. It is also helpful in treating memory lapses and Alzheimer's disease.
It helps stop production of arachidonic acid which is responsible for wrinkling and aging of skin. Topical creams containing DMAE help tighten skin and reduce wrinkles and fine lines.It is found to be effective in burning fat because of its involvement in the production of acetylcholine. It increases the metabolism in the body because of its thermogenic effect.It can be beneficial as an anti-inflammatory as well.It can reduce the amount of sleep required for a person by up to one hour.It can safely be used as a substitute for anabolic Steroids.
Research studies have shown that consumption of 200 to 500 mg of DMAE on a daily basis is helpful in improving health. However, it is important to start with a low dosage of DMAE and then gradually increase the dosage level to the optimum level. Higher dosage can cause headaches, insomnia and muscle tension. People suffering from conditions such as schizophrenia, mental depression and epilepsy should not have DMAE supplements. Pregnant and lactating women also should not have DMAE.
Summarizing, consumption of recommended amounts of DMAE is believed to be safe. Side effects due to consumption of DMAE are rare and not generally serious. However, it is important to use high-quality supplements in order to increase DMAE levels in the body and reap the benefits.
Serrapeptidase: Natural NSAID
March 27, 2012 03:26 PM
Serrapeptase, also known as Serratia peptidase is a proteolytic (protein-splitting) bioactive enzyme found in the intestines of the silk worm. This silk-worm enzyme is widely used in Europe and Japan in clinical therapy for relieving pain and inflammation. When the silk worm leaves the cocoon, it regurgitates the serrapeptase in to create a hole in the cocoon for its escape. It was soon discovered that serrapeptase enzyme has a unique property to dissolve dead material consisting protein without even harming the living tissue. This property of dissolving dead tissue can be used in treating many health conditions.
How Serrapeptase work?
Protein is the main component of most of the fibrous materials in the body. Once these fibrous materials out-live their purpose or are over-grown, they start causing serious disease conditions involving fibrosis. Fibrosis is an abnormal thickening and scarring of connective tissue caused by infection, injury, surgery or lack of oxygen. Serrapeptase works as an anti-fibrotic and helps in relieving the conditions in connective tissue scarring and thickening has occurred.
Health Benefits of Serrapeptase:
This proteolytic enzyme is considered an alternative to NSAIDS (Non Steroidal Anti-Inflammatory Drugs) that are used to treat osteoarthritis, rheumatoid arthritis and other inflammatory conditions. Serrapeptase has been used to treat fibromyalgia, colitis, Inflammatory Bowel Diseases, varicose veins, ovarian cysts, ear and throat infections, enlarged prostate and postoperative inflammation. Studies have shown its effective results in prevention and removal of arterial plaque.
Serrapeptase in relieving Pain:
Pain and Inflammation Reduction:
Serrapeptase is a great anti-inflammatory and analgesic agent. It reduces the inflammation and gives relief from the pain. It works by blocking the release of pain inducing amines from the inflamed tissues. Due to its pain relieving and anti-inflammatory properties, serrapeptase is used in treatment as an alternative to NSAIDS. This enzyme gives relief from mild to moderate pain like headache and backaches. Hence it is used all the inflammatory conditions such as colitis, sinusitis, arthritis and many more.
Serrapeptidase has an anti-fibrotic and fibrinolytic action that prevents and treats the accumulation of plaque in the arteries. Plaque is the accumulated deposits of cholesterol, fatty substances, cellular waste products, fibrin and calcium. Excessive plaque formation impairs the normal blood flow and cause partial or complete blockage, which also results in arteriosclerosis. Serrapeptidase helps to prevent build-up of plaque in the body. Due to its fibrinolytic action, it also helps in dissolving of proteins and breaking down atherosclerotic plaques. The dissolved deposits are eliminated from the body.
Hence, serrapeptidase prevents coronary artery diseases and improves cardiovascular health.
Due to its anti-inflammatory and mucus dissolving properties, Serrapeptidase is very beneficial for chronic sinusitis sufferers. Serrapeptidase helps in thinning and expelling the thickened mucus secretion present in nasal cavities of sinusitis sufferer.
Serrapeptidase helps in reducing the recovery time in any injuries, wounds or surgery. It promotes healing in post-operative wounds by reducing the inflammation and pain.
Serrapeptidase is available in the form of supplements. If you are taking NSAIDS for any healthy condition, substitute it with serrapeptidase supplement
Why Choosing 7-Keto DHEA Over Standard DHEA
February 25, 2012 06:36 AM
The Importance OF DHEA Nowadays
DHEA (Dehydroepiandrosterone) is probably one of the most abundant hormone that can be found in the human blood. Being produced in the adrenal cortex, this important Steroid it's very important in reducing body fat, cholesterol and also the alleviate angina. In addition to all that, DHEA has been widely used to treat coronary artery disease, Alzheimer's, sclerosis, depression, osteoporosis and even cancer. Because of this, DHEA is known under the name of “Fountain of youth.”
DHEA levels will usually decrease with age. This decrease might lead to high cholesterol levels, cardiovascular disease, neurodegeneration and even obesity in many cases. These are only a few reasons that make of DHEA an imperative hormone for our body.
What Makes 7-Keto DHEA Better Than Standard DHEA?
7-Keto Dhea it's similar to its cousin hormone, however it is much better for your body. Some of its extra benefits that can't be find in the standard DHEA are:
- Enhances your immune system.
- Improves your memory.
- Increases your muscular mass and strength.
- Help you lose fat naturally.
- Increases the activity of your thyroid gland.
- Reduces the signs of aging.
Overall, 7-Keto DHEA is a safer and a more potent derivates of standard DHEA, proved to be safer and with less side effects. 7-Keto DHEA is a real breakthrough as it represents the next generation of DHEA supplements. How was this discovered?
In the previous years, the University of Wisconsin conducted an extensive research in order to discover the best DHEA derivates. Over more than 150 DHEA derivates analyzed, a single compound stood out- it was 7-Keto DHEA. This compound provided greater benefits over a long-term period than the standard DHEA. Nowadays it is considered an improved and much safer form of this important hormone, called DHEA.
In addition to providing all therapeutic benefits of DHEA, this improved hormone won't be converted into some unwanted sex Steroids. It also lacks any other hormone- elevation that was commonly found in the standard DHEA supplements. This product makes you feel young again without endangering your body tissues or internal organs, compared to the traditional DHEA whose side effects were found destructive to some of your body tissues.
Why To Take This Hormone?
7-Keto Dhea was proven to be a safe product in a clinical trial, being tested on many people and animals. The only side effects this hormone might have are some mild heart palpitations and sometimes acne. Still, these side effects won't usually appear on people who take this product as prescribed and also avoid taking an overdose.
The benefits this hormone provides to our body are very real, as they were discovered at those who took this hormone for a longer period of time. Enhancing your immune system, the response to viruses is stronger. You will feel healthier and better protected.
When Should You Take It?
This hormone is to be taken only after you reached 30 years old, as you won't need it before that age. DHEA hormone begins to decrease considerably only after you reach 30, so this process will continue until you reach 70 or 80 years old. Taking the 7-Keto Dhea hormone will help you feel and be younger.
Guggul: An effective remedy to lower cholesterol levels in the body
February 22, 2012 11:34 PM
Guggul is a popular herb in Indian Ayurvedic medicine that is used to treat several ailments. Due to its miraculous healing properties, it has been used for centuries in India to treat a range of health conditions. Recently many clinical studies have been carried out to find out the potential health benefits of herb guggul. Research has shown that guggul helps in lowering total body cholesterol, especially the bad ones-LDL and triglycerides. Before we move on to find the positive effects of guggul on heart and cholesterol levels, let us find out the more about this wonder herb.
Botanically known as Commiphora mukul, guggul is a small shrub reaching up to a height of 4-6 ft. It is found in Central Asia, more common in India. It possess red colored flowers, thorns on branches and oval pulpy fruits. Guggul is prepared from the gum resin that is excreted by the bark of the plant. It contains phytosterols named guggusterones, aromatic acids, Steroids, sterols, lignans, fatty acids, organic acids and diterpenes. According to Indian traditional system of medicine, Ayurveda, guggul contains hot potency which helps in treating diseases caused by vata dosha prominence. It treats coating and obstruction of channels that helps in treating and preventing atherosclerosis and other medical conditions caused due to high levels of lipids in the body. Raw guggul exudate is not safe and it is always used after purification in milk.
How does the herb guggul help maintain good cholesterol levels?
The exact mechanism by which guggul lowers cholesterol levels is still not understood, but many theories have been proposed.
1. Guggul works by blocking the synthesis of cholesterol in the liver. Hence liver does not release excess LDL or bad cholesterol in the blood, thereby reducing the risk of many heart diseases.
2. According to studies, guggul has an impact on the functioning of throid gland and production of bile acids in the body, both of which play an important role in the metabolism of cholesterol.
3. Studies have indicated the role of guggul in preventing oxidation of cholesterol. Oxidation of LDL cholesterol leads to formation of plaques in blood vessels and causes Atherogenesis. The antioxidant action of guggul inhibits cholesterol oxidation and reduces the risk of Atherosclerosis.
The cholesterol lowering properties and antioxidant action make guggul a beneficial Anti-Atherogenesis agent. It can lower cholesterol levels by 14-17 percent and reduce triglycerides by 22-30 percent.
Guggul and heart benefits:
Guggul helps in promoting overall cardiovascular health. It reduces the adhesion of platelets and this reduces the rick of cardiovascular diseases. Studies have shown that Guggul when taken along with Inula racemosa helps in reducing chest pain and dyspnea associated with angina. It has potential cardi-protective benefits that keep your heart health. It helps in lowering blood sugar level and treating any inflammatory heart condition.
Health supplements are prepared from the extract of this highly beneficial plant. Consult your health provider before you start taking guggul supplements. When taken in recommended doses, guggul helps you keep your heart healthy and fit so that you can live a healthy life.
Use Turmeric Herb Instead Of Cox-2 Inhibitor for Pain Relief
February 17, 2012 07:15 AM
What Is a Cox-2 Inhibitor?
Cox-2 Inhibitor is a form of NASID. NASID stands for Non-Steroidal anti-inflammatory drug which function to bring inflammation down. It is one of popular painkillers. It is very useful since medical science has gained information about serious problem about inflammation. Yet, it has been reported that it causes fast heart rate. It is a risky heart rhythm condition which is also named with atrial fibrillation. Medical experts said that it is a serious problem because it might lead to the risk of heart failure. Besides, it might also cause stroke and even death.
As a form of NASID, Cox-2 Inhibitor will crucial to bring the inflammation down from a disease such as arthritis and an injury. In the United State, the common form of arthritis is Osteoarthritis. In short, this is the primary benefit of it. Besides that, it also functions as pain reducer. It is done by blocking proteins and enzymes made naturally by the body. However, it brings harm for our body on the other side. It seems to be side effects. Earlier research has noticed that it leads to the death.
As the solution, you can pick turmeric herb. It appears in a form of yellow colored spice. Similar to Cox-2 Inhibitor, it is very helpful for relieving the pain for arthritis. It is a perennial herb which originally grows in India. In the past, Indian people use it for cooking. Curcurmin becomes the most important part of turmeric. It is the most medicinal part contained in turmeric. We can easily find it in form of yellow color. Besides India, China has already use this herb in their daily live. For both Indian and Chinese, this herb has significant function as an anti-inflammatory. Besides, it also can be used as an antiseptic and several powerful ways.
Besides for curing arthritis, turmeric herb is able to inhibit the spread and the growth of cancer cell. It has been proved by a university of Texas study. The result concluded from its research shows that turmeric herb prevents the breast cancer to be spread out to the lungs. It works together with our body by identifying the mutated cells and then it kills them. To make it more effective, it is suggested to combine turmeric herb with cruciferous vegetables.
Other benefits of Turmeric
Another benefit taken from turmeric herb is a protection toward our heart. For several countries especially the United State, heart disease has become the number one killer. In this case, this herb will play the role to prevent the oxidation of cholesterol. It is very important since the oxidized cholesterol might lead to the heart attack and stroke. It is because this oxidized cholesterol is able to damage blood vessels.
Cox-2 Inhibitor has benefits yet they are not equal with the side effects created such as heart attack and also stroke. Having had similar function, turmeric herb is highly recommended to take for pain relief. For long time, it has been used for anti-inflammatory too. In short, turmeric herb is better choice than Cox-2 Inhibitor.
Natural Remedies for Arthritis
February 08, 2012 08:15 AM
Arthritis is a kind inflammation on one or more joint. There are many kinds of arthritis. Each kind has different causes. Most common causes are injury, metabolism problem, immunity disorder, infections, hereditary factors, and much more. The symptoms are various too. But generally, it includes joint pain, swelling, redness, warmth, and stiffness. When the arthritis goes more serious, it could lead to fever, weight loss, and fatigue.
There are many ways to cure arthritis. If the illness is quite serious, you need to go to a doctor. You can undergo a physical treatment. You can orthopedic bracing. Or, you could even need a joint replacement surgery. And if it is not so serious, you can just go to drug store to buy some analgesic, corticoSteroid, acetaminophen or some anti-inflammatory medications. But, you need to remember that every drug has side effects. Analgesic could lead you to nausea and stomach upset. CorticoSteroid can give make you bruise easily. It can also weaken your bones.
The best recommendation to avoid side effects is to go naturally. Natural remedies have negligible side effects. Those have been used by our predecessors to cure many illnesses effectively. And for arthritis, there are also some ingredients that could be useful. Here are some examples:
Curcumin is derived from the root of tumeric plant. Tumeric is commonly used for Indian cooking and Chinese medication. Curcumin can be an effective anti-inflammatory. It can also cure stiffness and pain. For a better result, combine curcumin with bromelain. Curcumin might be not good for a pregnant woman to consume.
Boswelia acid can also be an active anti-inflamatory. Commonly, it is used to cure several inflammatory problems such as asthma and some digestive ailments. Boswelia supplements sometimes are sold in capsule form.
3. Holy Basil
Holy basil is also known as Tulsi in India. In Ayurveda, tulsi is very sacred herb. That is why it is called as Holy Basil. In India, many houses have it planted on their yard and often use it to cure headache, influenza, and some digestive disorders. Many researches have found that holy basil also contains high anti-inflammatory and antioxidant. But it is not recommended for pregnant women.
Ginger has an active compound called gingerol. Gingerol is very effective to cure inflammatory. You can consume ginger in many ways. You can take it as a supplement. You can easily brew the ginger root at home and drink it when it is warm. You can also just eat it. But if you want to eat it, it would be better to eat it with other foods or you might get heartburn.
Glucosamine is the main element that forms cartilage and synovial fluids. It is formed by glycoaminoglycans and protein inside a human's body. Glucosamine sometimes are formed as glusosamine sulphate. It then is made as supplement and can be bought in a drug store. It is effective for many kinds of injuries and joint disorders.
6. Hyaluronic Acid
Hyaluronic acid is a compound can be found in synovial fluids, along with glucosamine. It is very important to keep the volume of synovial fluids and frictionless movement. When a human's body lacked of hyaluronic acid, they will experience an inflammatory conditions such as stiffness, joint pain, and arthritis.
Deer Antler Benefit for Vitality and Improved Health
February 06, 2012 04:06 PM
When men want to increase their strength and their vitality in doing daily activities, they can always consume deer antler extract, which is believed to be able to help the body system gain more power. Not many people may realize that using such extract can really improve their vitality and their strength. Some people may consider it as a hoax, but there're several proofs and evidences that show this particular extract can really improve the testosterone level in men.
Originally known as a part of traditional and ancient medical treatment, this deer antler extract can be consumed to improve the testosterone level as well as the overall performance of the body system. When men consume the extract, they're believed to be able to experience: - Development in body endurance, lean body ability, and muscle mass. - Quicker recovery period from any physical injury. - Better sexual functioning - this benefit can apply to men and women. - Higher and better energy level and vitality. - Improved and better immune system. - Aging delay, since the skin and the hair will have better cycle growth that make them look younger - Stronger nutritional support for the entire body system, especially the joints and the bones.
Deer antler extract isn't only helpful in those areas, but it also helps reducing stress level. Based on a medical observation done by Dr. Fenessy from New Zealand, this extract was quite beneficial when used in previous Russian study. The medical patients who had undergone gastrointestinal tumor surgeries were taking the extract prior to their operation. And they had shown quite amazing result; their stress level was decreasing. There was also another research that measured the mental ability of the students. They had been given the extract before taking math test. Based on the result, their mental ability was improving. Based on the study done in Russia and New Zealand, the Western medical societies are starting to do researches concerning the usage of the extract as vitamins so the consumer can really achieve the medical and optimal benefits.
So, what's the relation of deer antler extract and the testosterone? Medical experts believe that the antler can increase the production of the androsternedione. The androsternedione is a natural Steroid that is actually produced by the body. This substance is produced in the gonads and adrenal glands, which then changed into testosterone inside the liver. So, when people consume the antler, automatically, they will produce more androsternedione. When more androsternedione is produced, naturally the number of testosterone will also increase. Testosterone itself is also responsible for the improvement of metabolism and body's recovery ability.
This typical extract is mostly available in powdery form, although it's possible that it's also available in liquid form. People can always boil it, mix it with warm water, mix it with other herbs, or dilute it with alcohol. They can: - Combine it with ginseng for improved energy - Mix it with 40% of alcohol for tonic supplement - Combine it with Drynaria or Dipsacus for kidney treatment - Mix it with Dang Gui for strengthening the blood It's advisable that they should make a medium sized boil and then store it. They only need to consume the deer antler combination per ounce a day until the storage container is empty.
What Makes Phytoestrogen So Good For PMS?
October 18, 2011 04:12 PM
Phytoestrogens are considered as plant estrogens. These plant substances can function like the primary sex hormone Estrogen. This chemical compound is also known as "dietary estrogen" which is an assorted cluster of non - Steroidal plant compounds. As earlier, Phytoestrogens comes from plants and not produced by the body like the naturally occurring estrogen. These chemicals are not made available to the body naturally but by food or vegetable consumption. Though their source is different, estrogen and Phytoestrogen closely resembles each other chemically. They almost have the same structure making Phytoestrogen compounds act like natural estrogen inside the body.
Chemically, Phytoestrogen is not considered as a nutrient because health experts declared that any lack of this chemical in the body would not produce any sign or symptom of deficiency. Also, this chemical substance does not have any involvement in any of the body’s vital biological processes. However, despite this fact, Phytoestrogen can be employed for the effective relief treatment of Post - Menopausal Syndrome or PMS.
The signs and symptoms of Post - Menstrual Syndrome is associated with the decreased concentration of female sex hormone such as estrogen in the body. As estrogen levels in the blood decrease, body discomforts such as hot flashes, night sweats, mood changes and irritability may become apparent. In this situation, Phytoestrogen can be helpful in relieving such uncomfortable signs and symptoms. Phytoestrogens can effectively bind to estrogen – receptor sites inside the boy thus falsely giving the body a signal that there is an adequate amount of estrogen. Phytoestrogens can effectively mimic the action of estrogen mildly but sometimes antagonize its effect. Many studies have revealed that adequate supply of Phytoestrogen can effectively alleviate the discomforts of PMS.
Other than it ability to bind with estrogen–receptor sites, Phytoestrogen also changes the amount of natural body estrogen by interacting with certain enzymes in the body. This interaction with several enzymes may increase the effect and bioavailability of endogenous sex hormones. Studies have also shown that Phytoestrogen can improve the synthesis of Sex Hormone – Binding Globulin which is the hormone responsible for the binding and use – up of sex hormones inside the body.
The plants which are rich in Phytoestrogens include a variety group of foods. Legumes, whole grains and seeds contains abundant amount of this chemical compound. Soy, wheat berries, fenugreek, lentils ginseng, apples, yams and carrots are also considered as good source of Phytoestrogens. This beneficial chemical compound was discovered first on red clover plant which is considered to be very rich in Phytoestrogen. Phytoestrogen is also formulated in the form of capsule, tablet or powder supplements. Health experts highly recommend that women on the menopausal stage must take only less than one milligram of Phytoestrogen supplement daily.
If you want to reduce symptoms of low estrogen, give phytoestrogen a try!
What is Wild Yam Root And How Does It Help PMS And More?
July 25, 2011 02:44 PM
Wild Yam And Your Health
Wild yam root refers to a group of tubers related to the common yam. While the common yam is consumed as a vegetable, wild yam root is known for its medicinal properties. It has been linked to many studies in the past few decades. It is a source of the plant Steroid diosgenin, which is converted to progesterone in the laboratory. It has also shown to reduce cholesterol and triglyceride levels.
Dioscorea villosa is the plant species often referred to as wild yam root, inasmuch as most products and supplements that are marketed as wild yam obtain extracts from this plant. Its positive effects on health are attributed to Steroid-like organic compounds called saponins. Nevertheless, these saponins and other active ingredients of the root can also be derived in other closely related wild yam species.
Rebalances Female Hormones
Wild yam root is one of the most recognized plant species in the nutraceutical industry, especially in niches concerning the alleviation of hot flashes, night sweats, and other vasomotor symptoms. It is rich in compounds that precursors to human sex hormones, such as estrogen and progesterone.
Whether modified or not, the compounds extracted from wild yam root display estrogenic activities inside the female body, and they can be administered through the mouth or skin. They work normalize fluctuating levels of hormones, as is the case during menopause.
Counteracts Pain Chemicals
The phytochemical content of wild yam room is anti-inflammatory in nature. Not surprisingly, it has been used in the treatment of inflammation-induced disorders, such as rheumatoid arthritis, renal colic, ulcerative colitis, muscle cramps, abdominal pain, and inflammatory bowel disease.
Wild yam root suppresses the releases of endogenous compounds responsible for the perception of pain in certain body parts. In addition, it also inhibits the excessive productions of immune cells that trigger hypersensitivity and immune disorders, such as bronchial asthma and allergic rhinitis.
Boosts Bone Mineral Density
Extracts of wild yam root are commercially touted to prevent bone loss characteristic of osteoporosis. Since the human bones are the primary reserves of calcium and other minerals, they undergo a continuous cycle of demineralization to meet the mineral demands of other parts of the body.
The process of demineralization that alters bone density throughout life is called bone resorption. It is influenced by other factors, such as sedentary lifestyle and mineral deficiencies. With a balanced diet, regular consumption of wild yam root has been reported to easily reverse bone loss.
Reduces Overall Lipid Levels
There is a growing body of literature devoted to the effects of wild yam root on overall lipid levels in the blood. Wild yam root supplements are believed to lower utilization of triglycerides in the liver, limiting the releases of cholesterol, low-density lipoproteins, and free fatty acids into the bloodstream.
In addition, regular intake of wild yam root extracts appears to interfere with the breakdown of fats into easily digestible fatty acids and their subsequent absorption in the small intestines. This results in lower fat intake and healthier levels of cholesterol.
What is stopping you from trying it?
How Does Progesterone Cream Help Ease Hot Flash Symptoms?
June 21, 2011 11:01 AM
Progesterone And Hot Flashes
Progesterone cream is an all natural remedy for hormonal imbalances in the female body. It has grown in popularity in the past few years largely owing to very strong anecdotal evidence. Its use in the management of hot flashes has produced very encouraging results, and thus has become a mainstay of alternative treatment for vasomotor symptoms of menopause and premenstrual syndrome.
Plants contain fats and oils that can be modified in the laboratory to partially synthesize progesterone. The active ingredient of most progesterone creams in the market is diosgenin, which is a plant sapogenin that occurs naturally in wild yams. Diosgenin has long been noted for its Steroidal activity inside the human body, but it has been successfully converted to progesterone only recently.
Reverses Estrogen Dominance
The concept of estrogen dominance is central to the appearance of hot flashes. A group of medical professionals believe that vasomotor symptoms are brought on by fluctuations in hormonal levels, among other factors. While both groups of female sex hormones experience changes, progesterone is thought to approach near depletion in comparison with estrogen. Hence, the latter dominates.
Progesterone creams work on the principle of reversing estrogen dominance. They are formulated to facilitate optimum absorption into the body. While their active ingredients, such as diosgenin, have been noted to produce estrogen-like activities when unmodified, progesterone creams function exactly in the same manner as endogenous secretions of progesterone.
Increases Progesterone Levels
Hot flashes are often linked to changes in body temperature. It has long been postulated that hormonal imbalances have an effect on the hypothalamus, which regulates body temperature. It is believed that depleting levels of progesterone lead to a series of chemical reactions that confuse the biological thermostat, resulting in vasodilation of blood vessels close to body surfaces.
Progesterone creams effectively relieve hot flashes because the active ingredients are capable of penetrating the part of the skin that leads to the blood vessels. There is very good evidence that topical applications of progesterone are readily absorbed. Since fats and oils from plants have high absorption rates, progesterone creams are certain to increase progesterone levels in no time.
Normalizes Hormonal Changes
There has not been any contraindication associated with the regular use of progesterone creams as most of them are formulated in concentrations suitable for use at any time of the day. In fact, it can be applied to the skin even in the absence of hot flashes to prevent any vasomotor symptoms. A growing of body of literature has noted its efficacy in managing hormone-related imbalances.
More importantly, progesterone creams have shown great promise in stabilizing hormone levels in the long run, making it an ideal remedy for women suffering from premenstrual syndrome. Also, it is very likely to help women who are surgically menopausal as they experience very intense episodes of hot flashes that last until the natural age of menopause.
Grab some progesterone today and feel the relief it can bring!
Fight Inflammation, Gastric Problems, and Arthritis with Boswellia
June 14, 2011 11:49 AM
How Does Boswellia Fight Inflammation.
Boswellia fights inflammation through the action of a family of anti-inflammatory terpenes known as boswellic acids. Inflammation is a natural reaction of your immune system to tissue damage and infection, and is often associated with conditions such as arthritis, sports damage to bones and joints and bacterial infections caused by cuts and grazes. There are more serious inflammatory conditions of course, such as asthma, and boswellic acids act in the same way as non-Steroidal anti-inflammatory drugs (NSAIDS) without their unwelcome side effects.
Among the causes of inflammation are inflammatory mediators such as leukotrienes, the biosynthesis of which is blocked by boswellia. Another is the 5-lipoxygenase enzyme, also known as LOX-5, and again, the terpenoid anti-inflammatory boswellic acids block this so that the causes of inflammation in the above conditions are severely restricted. Boswellia extract is a good supplement to take for those suffering any form of arthritis, joint pain or even asthma.
Using Boswellia to treat Arthritis
Boswellia can be used to treat both osteoarthritis and rheumatoid arthritis, although rheumatoid arthritis is not always easy to control. Arthritis is an inflammatory condition, in the case of osteoarthritis the inflammation being a natural response to joint damage and infection of the synovial fluid generally caused by wear and tear on the joint with aging, and also by sports injuries.
Rheumatoid arthritis is a form of immune disease caused by the body attacking its own joints, and while the terpenoid anti-oxidants known as boswellic acids can help to mediate the pain and other symptoms, it can do nothing to cure the condition.
If you are suffering pain through arthritis, and your joins are tender and swollen, a supplement consisting of an extract of boswellia or its terpenes can help to relieve these symptoms and to offer pain relief equivalent to that offered by synthetic NSAIDs such as aspirin and Ibuprofen.
Gastric Problems and Arthritis Pain? Perhaps Boswellia Can Help
Extracts and supplements based on the resins of the boswellia tree are commonly used to treat inflammatory conditions, and reduce the severe pain of rheumatoid and osteoarthritis, ease the discomfort of colitis and also help ease the symptoms of those suffering asthma. Each of these is an inflammatory condition that would otherwise have been treated using NSAIDs, or non-Steroidal anti-inflammatory drugs.
NSAIDs have a number of side effects, being particularly unsuitable for those with ulcers or any other gastric problem. The terpenoids contained in boswellia extract an effective alternative to these drugs that many try to avoid taking. Long-term use of boswellia appears a lot safer than long-term use of NSAIDs, since it doesn't promote the severe gastric problems of these synthetic drugs, such as irritation of the stomach lining or even ulcers. If you already have ulcers or other gastric problems then NSAIDs area define no-no for you, and boswellia is the ideal substitute.
Grab some boswellia today and experience relief for your self!
How Does Holy Basil Extract Help With Pain
June 06, 2011 02:43 PM
Holy Basil And Your Health.
Holy Basil, technically known as Ocimum tenuiflorum, is a perennial plant which is a member of the family Lamiaceae. This kind of plant is commonly cultivated in the tropics region but can also be seen as an escape weeds. Holy Basil plant is an upright shrub with many hairy branches that can grow up to 30 to 60 centimeters in height. It has an aromatic leaves in green color that are slightly toothed. It also bears flowers which are purple in color and also has a strong scent. Holy Basil has many medicinal uses. In fact, in South Asian regions, Holy Basil is commonly utilized as an herbal tea.
Holy Basil claimed to be an effective pain treatment. Clinical studies show that this plant contains high amounts of Eugenol which mimics the actions of COX – 2 Inhibitor drugs. COX – 2 Inhibitors is a pain killer which is classified as Non – Steroidal Anti – Inflammatory Drug or NSAID. This type of drug is directly targets the enzyme Cyclooxygenase – 2 which is responsible for inflammatory response. Inflammation is associated with swelling which further cause pain. If an area is swollen, the nerve endings are compressed therefore pain is felt.
Aside from its potent pain alleviating property, Holy Basil is also useful in reducing blood sugar levels. This is the reason why it is utilized as an effective treatment for diabetes mellitus. Holy Basil also has an antioxidant effect. As we know for a fact, antioxidants are useful in eliminating harmful toxins in the body known as free radicals. Free radicals can damage cells and even tamper DNA formation during cellular division. Other benefit of Holy Basil includes its anti – stress property. Holy Basil leaves are considered to be an adaptogen or anti – stress agent which protects an individual against various stressors. Experts recommend that an individual can consume a dozen of Holy Basil leaves two times daily to prevent stress. Holy Basil leaves are thought to purify blood thus improving blood circulation and tissue oxygenation.
Aside from Eugenol, Holy Basil also contains the compound Carvacrol which has a strong antibacterial property. Carvacrol has the capacity to inhibit the growth of certain bacteria such as E. coli and Bacillus cereus. Carvacrol is also an effective digestive aid. Research reveals that Carvacrol is can alleviate gastric upset and improve digestion of food and absorption of nutrients.
Holy Basil extracts are reported to be safe and effective in helping alleviate pain and treating other health conditions. Experts suggest that Holy Basil is not for long – term use. It must be used only for a maximum of four weeks. Pregnant women and breastfeeding mothers must not use this supplement to be completely safe. Holy Basil is discovered to slow blood clotting therefore it must not be used within two weeks before and after any type of surgery. Finally, though Holy Basil extracts are relatively safe, it would still be best to consult a qualified healthcare provider and discuss with him or her your health status and history.
Get some today and reap the benefits of this wonderful herb for yourself!
Does Progesterone Cream Really Help with Hot Flashes?
April 19, 2011 02:53 PM
Progesterone cream is a derivative of Steroids that occur naturally in plants. It is commercially touted to help a variety of vasomotor symptoms related to menopause, including hot flashes. Proponents of progesterone believe that the undesirable effects of menopause on the female body are triggered by an imbalance of female Steroid hormones, with a noticeable dominance of estrogen.
Women experience the transitory years of menopause with symptoms that are largely variable. That being said, hot flashes are one of these symptoms that all menopausal women are likely to experience at least once. It is less prevalent in some, but a significant fraction complains about a varying degree of sensation of heat often accompanied by rapid heartbeat.
Hot flashes afflict women of all ages. It is not unheard of to have women in their 20’s complain about night sweats and related symptoms of changes in hormones. Sex hormones of the female body are lowest at night, the reason why a lot of younger women experience episodic flashes at night, but not during daytime. However, outbreaks of hot flashes may happen at the most random times, and to this day the causes are not well understood.
Progesterone may be best known for its biological roles during pregnancy as it is important to the development of the fetus. It belongs to a class of Steroid hormones called progestogens, which are in fact biological precursors of other sex hormones, such as androgens and estrogens. In addition, it plays a central role in thermogenic function during ovulation and even found in mucus membranes within subcutaneous regions.
Dilation of Blood Vessels
Sex hormones of the female body, especially progestogens and estrogens, undergo a steep decline after the age of 40 especially in women into their menopausal years. Hot flashes in general are considered vasomotor symptoms in that they are visible effects of the sudden opening of blood vessels close to the skin. Sometimes, the same dilation of the blood vessels produce noticeable changes in heartbeat most women refer to as palpitations.
Effects of Progesterone Cream
There are drugs that cross the layers of the human skin and permeate the microcirculation of the dermis, reaching systemic distribution in the process. Progesterone cream is believed to work on the same principle. It is lipid-soluble, and as such capable of interacting with subcutaneous tissues that largely comprise lipids. Blood vessels in regions where hot flashes occur are believed to have dilated, making it ideal for topical applications to work.
All-natural Plant-based Steroids
Progesterone cream is obtained from fats and oils of plants. Most products derive it from a specific species of wild yam while others utilize soybeans. Noted for their estrogenic activities, these plant Steroids are converted into progesterone in the laboratory. The product is thought to act exactly like the hormone produced and released by the human body. Anecdotal evidence is positive that progesterone cream normalizes progesterone levels in the skin, putting an end to hot flashes.
For those who suffer from hot flashes progesterone cream could be the answer.
Policosanol, Cholesterol and how its tied together
January 27, 2011 10:44 AM
Cholesterol is a fatty substance that is essential to your health! If that sounds contrary to what you have been hearing about cholesterol, then you don't have all the information. Cholesterol is essential for the synthesis of hormones in your body, including the Steroidal hormones such as the sex hormones and those that regulate your blood sugar. So you cannot afford to eliminate all cholesterol. However, you can reduce it, and you can also take steps to reduce the problems that cholesterol can cause.
You have likely heard of LDL (bad) and HDL (good) cholesterol - there is no such thing as bad or good cholesterol. Without 'bad' cholesterol you would not be alive! However, cholesterol is not soluble in water, so cannot pass round your bloodstream by itself. LDL stands for Low Density Lipid, which is a fatty substance that can attach to cholesterol and act as a type of ferry, to carry it around your blood.
The problem is that LDL is easily oxidized by the free radicals formed by your metabolism and breathing in traffic and industrial emissions. This causes it to release the cholesterol that then sinks and deposits as a plaque on the inside of your arteries, eventually blocking them and causing strokes and heart attacks. The HDL cholesterol is responsible for carrying the unused cholesterol back to your liver, so does not block your arteries.
Policosanol can reduce the amount of LDL cholesterol while still maintaining sufficient for your needs. It can also increase the HDL cholesterol: if more High Density Lipids that are not oxidized are available, then more cholesterol can be carried by them, and also possibly reduce the plaque build-up. This is what policosanol does: it reduces LDL and increases HDL cholesterol.
Curcumin and Pain
December 02, 2010 12:33 PM
Make no mistake about it: curcumin has long been identified as the compound responsible for the anti-inflammatory benefits of the ginger plant turmeric. The herb turmeric has been around for ages, cultivated for its wide array of culinary and medicinal uses that transcend regional and cultural boundaries. Apart from the popular use of its powdery form in bread, cakes, ale, and beer as a flavoring, the plant contains up to 5 per cent curcumin, which is one type of polyphenols now being looked into for its antioxidant properties.
Prostaglandin and Inflammation Pain
Autocrines and paracrines are contained in almost all tissues and organs to effectively participate in bodily defenses every time the systems call for them, for example in treating wounds. Prostaglandins are either autrocrines or paracrines that take on the job of signaling the tissues and systems implicated in defensive reactions when the body detects unwanted and harmful stimuli. Cells release autocrines to have an effect on the same cells and paracrines to aid nearby cells, making these compounds function as effective chemical messengers in immediate vicinities anywhere in the body as they are short-lived.
Prostaglandin is known as the chemical messenger causing pain and igniting fever among others. Defensive mechanisms start when cells release mediators, including prostaglandin, which brings about the known signs of inflammation. Prostaglandins relax smooth muscle cells within the walls of blood vessels in the area of inflammation and promote the flow of needed fluids like blood and plasma proteins into the spot, leading to the subsequent redness and swelling. They continue to mediate the healing process by permitting the entrance of neutrophil granulocytes, the front-line soldiers against harmful stimuli, and consequently put an end to invading pathogens. The same group of chemicals also increases pain at the same time, for example the joint pains associated with inflammation called arthritis.
Curcumin and Anti-inflammation
Painkillers, classified as analgesic drugs, work in a number of ways that in the end relieve the continual sensitization of certain body parts to pain. One group called non-Steroidal anti-inflammatory drugs such as aspirin and ibuprofen targets the enzyme that catalyzes the synthesis of prostaglandins aim to reduce levels of prostaglandins.
Curcumin works on the same principle. Take for example, joint pains caused by arthritis. Be reminded that individuals who complain about joint pains are suffering from varied forms of medical conditions, which one way or another contribute to the pain in addition to having excessive levels of prostaglandins in the joints involved. Damage to the joint brought about by wear and tear or forced movement involving joints spurs the body to take defensive measures that include inflammatory effects, thus the pain. The intake of curcumin and its derivatives act on the cells in its production of prostaglandins, resulting in both the easing of pain and the lessening of inflammation.
Turmeric, Curcumin, And Good Health
November 11, 2010 03:48 PM
Turmeric and its historyTurmeric is not just an ancient Asian spice but also an effective traditional alternative medicine used worldwide. Turmeric is a spice that originates in India and has been long used in both Ayurvedic and Chinese traditional medicine. This spice comes from the herb Curcuma longa L. which is a member of the Curcuma botanical group, a part of the ginger family of herbs called Zingiberaceae. The root and rhizome (underground stem) of this plant is crushed and powdered into ground Turmeric. Ground Turmeric is used worldwide as a seasoning and the main ingredient in curry powders. Ground Turmeric is also the source of Curcumin, an extracted potent substance also used as alternative medicine nowadays.
Turmeric, because of its Curcumin content, has many health benefits to humans. Firstly, Turmeric has an anti-inflammatory property. Its active ingredient, Curcumin, has been proven to help reduce inflammation. Decade to decade, Turmeric has been used as an anti-inflammatory agent to treat inflammations of the skin and muscles. Experiments done by researchers also revealed that this herb has been effective in decreasing post-surgical inflammation. This important health benefit of Turmeric is considered to be a result of the herb’s ability to slow down, if not to totally stop, Eicosanoid Biosynthesis, one of the processes the immune system undergoes during an inflammatory response.
Secondly, as a result of its anti-inflammatory characteristic, Turmeric also has an anti-arthritic property. It is widely used as an alternative medicine for rheumatoid arthritis and other autoimmune disorders. In addition, this herb also has a natural painkiller effect. Studies show that it has similar actions to the commonly used medications such as COX-2 inhibitor and NonSteroidal Anti-inflammatory Drugs.
Thirdly, several studies have shown that Turmeric is also helpful in lowering the level of bad cholesterol in the blood known as the Low Density Lipoprotein or LDL and in increasing the body’s good cholesterol, High Density Lipoprotein or HDL. An increased level of LDL promotes cholesterol plaque deposits to the walls of blood vessels, most commonly in the arteries of heart. These plaques narrow the arterial diameter hence resulting to high blood pressure and even circulation blockage. An arterial block may cause poor circulation and oxygenation to heart muscles leading to cardiac injury then infarction. This is oftentimes the cause of heart attacks. It has also been discovered that Turmeric can promote excretion of dietary fats. Thus, controlling the intestinal uptake of fats, especially cholesterol.
Turmeric - Powerful AntioxidantLastly, Turmeric is also widely used because of its anti-oxidant property. Studies demonstrate that Turmeric is effective in eliminating free radicals in the body. These free radicals are harmful. It may cause cell mutations which can lead to tumor formation and, worse, cancer.
This herbal plant can be prepared in the household by pounding and pressing its roots to be able to extract the juice out. It is then mixed with water and may be used topically or by nasal inhalation. The root can also be lightly cooked and eaten. Turmeric is also helpful in earaches and to clear clogged sinuses thus easing breathing. This herb can also be purchased in bulk powder or standardized forms to ensure its beneficial properties are intact.
Myth: Agave Nectar is adulterated or mixed with HFCS.
April 08, 2010 04:08 PM
There are two methods of making the Agave Nectar from the juice of the plant. One uses a non-GMO enzyme and the second is via thermal hydrolysis. Both process achieve the same goal which is to separate the naturally occurring Fructans which are complex sugar molecules into their simple sugar components fructose and glucose.
Unlike the process of High Fructose Corn Syrup (HFCS), which creates fructose out of the glucose from the starch found in milled Corn, Agave Nectar simply separates Fructans or Inulin, a complex naturally occurring sugar into Fructose and Glucose.
Our producers do not use any sort of chemicals in the process and no foreign material is being added such as HFCS. Filtration and evaporation of excess moisture are the rest of the process. The evaporation is done in a vacuum evaporator.
No research has pointed that Blue Agave contains Anodin and Dinordin, the Steroid derivatives with contraceptive effects that could lead to a miscarriage. This is clearly a cruel scare tactic. The truth is that there are many types of saponins and they are in a lot of foods we eat. Most beans and legumes, soya beans, onions, paprika, alfalfa - these all contain various saponins. Saponins are phytosterol compounds that occur naturally in some plants. Saponins have antimicrobial and antifungal properties, along with anti-inflammatory and immune-stimulating properties.
From the prehispanic times, the only sweet treat available to Indians in Mexico was the cooked leaves of the agave plant. They are still in markets all over Mexico. If there would be any kind of dangerous substance, this would be the absolute extreme case of exposure to it; not a single case of any problem has ever been reported, this goes back over 700 years.
Agave Nectar in its present form has been sold for over 12 years all over the world, including western Europe, Japan and the U.S.. The product has a proven record of safety and is deemed safe by the FDA and all regulatory bodies all over the world and there has never been a report of agave nectar linked to a miscarriage.
Madhava's Agave Nectar does not contain corn syrup, corn products, or any adulteration of any sort. Guaranteed. Our Agave Nectar is 100% pure from the agave plant with no additives whatsoever.
We package our agave nectar at our facility in the foothills of the Colorado Rockies. Madhava's Quality Control representatives routinely visit and inspect all our suppliers’ facilities in Mexico. The suppliers are Organically Certified and 3rd party audited or currently in the process. In addition our facility in Colorado is USDA Organic Certified and we are routinely audited.
Now foods and GMP Practices
February 04, 2010 12:36 PM
Author: Michael Lelah, Ph.D, Technical Directory, Now Foods
It should come as no surprise that 2009 was a challenging year with regard to the timeliness of order delivery, not just at NOW, but on an industry-wide scale. Many of the brands you carry have not been able to meet your demands.
In 2009 all medium-sized dietary supplement manufacturers, including NOW Foods, were officially required to meet the FDA's new dietary supplement cGMPs (current good manufacturing practices). NOW has placed very high quality standards on our products, and has been certified by NPA's stringent GMPs since 2000. Now that the FDA has started auditing manufacturers in our industry, we have found that the FDA requirements for the cGMPs are more strict than the early interpretations of experts.
This has resulted in ourselves and our industry being less prepared than anticipated, affecting the order fulfillment rates of many companies. We are actively working to respond to this.
Let's review the new FDA cGMPs. Good Manufacturing Practices, or GMPs, are manufacturing control systems designed to ensure that health products are manufactured in a consistent and safe manner. Standard operating procedures, specifications for all ingredients and products, and lab testing are cornerstones of GMPs. The FDA cGMPs are considerably rigorous, and by the FDA's own estimates, 25% of the brands you carry could be out of business as a result of not being able to meet their new cGMPs. Moreover, even for reputable brands, there is a lack of clarity on what the FDA expects, as much of this is new.
You might be wondering what all of this has to do with your orders? We at NOW Foods, along with other reputable manufacturers have increased our quality control efforts to meet the new FDA cGMPs. There are more requirements for ingredients and finished products, more documentation and more testing. The breadth of NOW's product line requires testing of thousands of ingredients. Based on the extensive nature of these efforts, coupled with disruptions in the supply chain, your orders have most likely been affected.
We are now better prepared to serve you. We are taking the safety of our products to entirely new levels and doing everything in our power to expedite the delivery of NOW products to your door.
Here are just a few examples of what we're doing:
Here's what you can expect from NOW Foods in 2010:
At NOW Foods we are continuing to work hard to meet your needs, despite the increased challenges to our supply chain. We hope and anticipate that as we move into 2010, you will reap the benefits of our quality and fulfillment efforts.
October 20, 2009 12:02 PM
For thousands of years feverfew has been used for the treatment of various ailments. History is full of references to feverfew. Dioscorides, an ancient Greek herbalist, recommended the use of feverfew almost two thousand years ago, as he valued the herb for childbirth, fevers, melancholy, and congestion of the lungs. It was also suggested for arthritis. In 1772, feverfew was suggested to be used to treat painful headaches. Many people believe that feverfew obtained its name from its use as a remedy for bringing down fevers, but this has been determined to be incorrect. Instead, the name came from the traditional Old English name for feverfew, featherfew. Featherfew came from the feather-shaped leaves of the feverfew plant.
Feverfew has been used for a long time as a natural remedy for pain relief, as it is considered an excellent remedy for migraines. This herb was used to treat any kind of pain and helped with chills and fever. Additionally, it helps in relieving colds, dizziness, tinnitus, and inflammation from arthritis. The herb works gradually and with a gentle action that allows the body to heal itself.
The most popular use of feverfew is in the prevention and relief of migraine headaches. In a study, those given the placebo had an increase in frequency and severity of headaches, nausea, and vomiting. On the other hand, those given the feverfew capsules had no increase in frequency or severity of migraines. A randomized, double-blind, placebo-controlled, crossover study was done on seventy-two volunteers. One group received capsule dried feverfew leaves, while the other received a placebo. The group taking feverfew showed less severity of attacks and a reduction in symptoms that were associated with migraines, including vomiting. There was a definite improvement in the group using feverfew and no serious side effects resulted. Because some forms of migraines are believed to be associated with abnormal platelet behavior, feverfew may be beneficial as it has been found to help restrain the release of serotonin from platelets. This prevents a migraine from occurring.
It is thought that feverfew may also be a useful treatment in cases of rheumatoid arthritis. This is because of its ability to inhibit the formation of inflammation-promoting compounds like prostaglandins and leukotriene. This herb seems to have similar properties to non-Steroidal anti-inflammatory agents (NSAIDs), like aspirin. Feverfew may actually be even more effective with a lot fewer potential complications. Some of the studies involving feverfew and migraines have shown that feverfew may also lower blood pressure.
The leaves and flowers of the feverfew plant are used to provide alterative, analgesic, anti-inflammatory, antimicrobial, aromatic, bitter, carminative, emmenagogue, febrifuge, nervine, parasiticide, mild purgative, stimulant, and vasodilator properties. The primary nutrients found in this herb are iron, niacin, manganese, phosphorus, potassium, selenium, silicon, sodium, vitamins A and C, and zinc. Primarily, feverfew is extremely helpful in dealing with chills, colds, fever, headaches, sinus headaches, and inflammation.
Additionally, this herb is very beneficial in treating aches, ague, allergies, anxiety, arthritis, insect bites, poor circulation, dizziness, gastric disorders, nervous headaches, hot flashes, indigestion, and menopausal symptoms, absent menstruation, nervousness, tinnitus, and vertigo. For more information on the many beneficial effects provided by feverfew, please contact a representative from your local health food store.
Glaucoma (loose your eye sight)
February 16, 2009 01:18 PM
Glaucoma is a group of diseases that affect the optic nerve and can lead to irreversible vision loss. It is usually associated with elevated fluid pressure within the eye. All forms of glaucoma can cause damage to the optic nerve and lead to vision loss, even blindness, if left untreated. About 2.2 million Americans have been diagnosed with glaucoma and as many as 2 million more could have it and not yet know. It is one of the lading causes of blindness and is expected to become more prevalent in years to come due to the growing population of older adults.
Those people who are at greatest risk for developing glaucoma are people over the age of sixty, people of African ancestry, and people with diabetes, high blood pressure, severe myopia, or a family history of glaucoma. Smokers also have an elevated risk, as do those who have sustained eye injuries or who have used Steroids for an extended period of time.
About 3 percent of Americans are believed to have open-angle glaucoma, which is the most common form of this disease. Because this disorder causes no symptoms until it is quite advanced, only about half of those who have it are actually aware of it. In open-angle glaucoma, there is no physical blockage and the structure of the eye appear to be normal. However, the drainage of fluid is inadequate to keep the intraocular pressure at a normal level.
The most pronounced symptoms of open-angle glaucoma are the gradual loss or darkening of peripheral vision and a marked decrease in night vision or the ability of the eye to adjust to darkness. Other possible symptoms include chronic low-grade headaches, the need for frequent changes in eyeglass prescription, and/or seeing halos around electric lights.
A far less common, yet more serious, form of glaucoma is closed-angle glaucoma. Closed-angle glaucoma is much more dangerous than open-angle forms because it almost never manifests any symptoms until very late in the condition. By that time, vision may be irreversibly damaged.
Glaucoma probably has many causes, with many scientists believing it may be closely linked to stress and nutritional problems or disorders like diabetes and high blood pressure. Some think that excessive amounts of glutamic acid, which is a nonessential amino acid, may be involved. Glaucoma has also been linked to deficiency in nitric oxide, which is a molecule that is critical for healthy blood vessels. Problems with collagen, the most abundant protein in the human body, have been linked to glaucoma as well. Collagen increases the strength and elasticity of tissues in the body, especially those of the eye. Collagen and tissue abnormalities at the back of the eye contribute to the clogging of the tissues through which the intraocular fluid normally drains. This results in elevated inner eye pressure, leading to glaucoma and related vision loss.
The following nutrients are considered to be very important when dealing with and preventing glaucoma: choline, essential fatty acids, glutathione, rutin, vitamin A, vitamin B complex, vitamin C with bioflavonoids, vitamin E, alpha-lipoic acid, magnesium, a multivitamin and mineral complex, and zinc. Additionally, the following herbs are helpful: bilberry, chickweed, eyebright, coleus forskohli, fennel tea, chamomile, ginkgo biloba, zinc sulfate, jaborandi, and rose hips.
To resolve issues with the eyes, one must change their diet, exercise, and take supplements and herbs like what are listed above. Medical doctors are at a loss as to how glaucoma happens but they can help stop the progression of this disease if detected early on. Always consult your doctor before adding vitamins and herbs to your diet, vitamins and herbs are available at your local or internet health food store.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
December 10, 2008 10:48 AM
Hoodia Gordonii is a South African succulent plant of the family Apocynaceae. They are remarkable similar in appearance to cacti, although they are totally unrelated to them and grow predominantly in the region of Central Namibia in the south west of Africa, up to the southern regions of Angola. They are most commonly found in rocky ground and on the plains.
There are several species of hoodia, some of them grown domestically, and it is Hoodia gordonii that is used as an appetite suppressant in hoodia weight loss pills. Although the plant has historically found use in the treatment of infections and gastric problems, most interest is displayed in its use by the bushmen of the Kalahari Desert to suppress their appetite during long hunting trips when food and water are scarce.
The active ingredient was isolated in 1977, and given the name P57: the product is therefore often referred to as Hoodia P57. It was patented by its discoverers, the CSIR (South African Council for Scientific and Industrial Research) and a license granted to UK company Phytopram, who worked together with Pfizer to isolate the active ingredients and manufacture them synthetically. This was found to be very difficult, if not impossible, since any synthetic form of the extract failed to display any hunger-suppressant properties.
Finally, the rights to the main ingredient were released by Pfizer in 2002, thus indicating that it was of no commercial benefit to them. The main problem they admitted with synthesizing P57 was not only the difficulty in doing so, but also that there were side effects of the extract on the liver caused by other components that could not be removed. No synthetic form of hoodia is therefore available, and only the natural plant is used in current Hoodia 57 preparations.
The rights of the San Bushmen to the plant were recognized by the CSIR in 2002, and not only do they receive a proportion of the profits of marketing hoodia, but also the plant is protected with wild-harvesting licenses provided to only certain individuals and companies. Due to the rising popularity of the hoodia weight loss industry, the plant has been named as an endangered species in the wild.
It is believed that the active ingredients are Steroidal saponins that can fool the body into believing it is full. This theory is based upon the effect on appetite of glucose concentrations in the blood. Your appetite is controlled by the amount of unconverted glucose in your blood, and glycogen in the liver. When you eat carbohydrates, they are digested and converted into glucose which is absorbed into the bloodstream.
Under normal conditions your blood glucose levels increase to a level where a signal from hypothalamus stops you feeling hungry. Insulin is then secreted from the pancreas to prepare your cells to use that glucose in the mitochondria to create energy by means of the Kreb's Cycle, or Citric Acid Cycle as it is also known. This reduces the concentration of glucose in the blood, and once it reaches a certain level the body begins to use its emergency energy supply, glycogen, that is stored in the liver.
A signal then informs the brain that more glucose is needed. You then feel hungry again, and this cycle is repeated several times a day in a normally healthy person. This cycle is controlled by certain hormones in the brain, specifically in the ventromedial center of the hypothalamus, where it is believed that the ATP (adenosine triphosphate) availability controls the release of the hormones involved.
ATP is the molecule of energy, and as the concentration of blood glucose and of glycogen drop, then the amount of ATP produced also drops and this is detected in the hypothalamus, which reacts by releasing ghrelin. Increased leptin increases the feeling of satiety and ghrelin increases the feeling of hunger. Serotonin acts on the brain to increase the effect of leptin in the hypothalamus, and therefore make us feel less hungry, or more satiated.
It is believed that hoodia gordonii, or the Hoodia P57 component of it, fools the brain into believing that your blood glucose or glycogen levels have reached the point at which it should trigger a satiated response, so that you stop eating even though your ATP levels might be low. The Steroidal saponins that it contains is believed to be ten thousand times more effective than glucose in stimulated the secretion of serotonin.
Hoodia has also been found to contain a number of glycosides, including pregnane glycosides that some studies have indicated to help control appetite of the subjects tested. Most of these tests have been carried out on animals, although Hoodia weight loss preparations are offered in a form standardized on both Steroidal saponins and pregnane glycosides.
Hoodia gordonii is becoming so popular as a weight loss product that its export is being monitored by the South African government. It has become so endangered that, since 2005, only hoodia grown on commercial farms is permitted an export license, and exporters must obtain a license from the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES). Importers also require a permit from the US department of Agriculture, and a CITES certificate is also needed to re-export the finished product.
Because of this, more hoodia weight loss pills are being sold than there is hoodia gordonii to produce them. It is not uncommon for cacti such as the prickly pear cactus from Mexico, to be used, or for low concentrations of hoodia to be bulked up with fillers. Neither of these is of any use as an appetite suppressant, the former having no active ingredients whatsoever and the latter containing only traces.
If you are purchasing hoodia, therefore, be aware of this. Request sight of the CITES certificate and USDA permit, and also the analysis results by an authorized laboratory to confirm that the product is what it purports to be. Otherwise, there is some evidence that Hoodia gordonii can help you reduce weight, although to date there are only four recognized analytical laboratories registered to analyze the active content of hoodia weight loss products.
Finally, check for the analysis certificates. All Hoodia weight loss products should be analyzed by each of three methods: Microscopy, High Performance Thin Layer Chromatography (HPTLC) and High Performance Liquid Chromatography (HPLC) - all there are needed. The four authorized laboratories are: the University of Mississippi, Chromadex labs in Irvine California, Alkemist Pharmaceuticals and Advanced Laboratories, Smithfield, NC.
No others will do, so if your Hoodia weight loss preparation has not been analyzed using the three methods by one of these laboratories, don't buy it, even if it can show the CITES and USDA documentation.
Grape Fruit Pectin Fiber
October 21, 2008 12:56 PM
Grapefruit pectin fiber is a source of soluble fiber that can bind to cholesterol and inhibit the formation of atherosclerosis. It is also effective in maintaining good blood sugar levels, and promoting a healthy colon. However, before discussing how grapefruit pectin fiber works in these ways, it is first necessary to explain how they occur in the first place.
First cholesterol. This is a Steroid lipid, most of which is biosynthesized by your body rather than being present in your diet. Although it has a bad name health wise, cholesterol is actually essential to good health because it helps your digestive system break down fast, it strengthens cell walls and is a major ingredient in the manufacture of vitamin D by your liver. It is also essential for the formation of several hormones, including cortisone, cortisol and aldosterone by the adrenal glands, and also of estrogen and testosterone. A bloodstream without cholesterol is therefore not good for you.
Given that cholesterol is essential for good health, then why does it have such a bad press? The root cause of that is that cholesterol is not water soluble, and to be carried round the bloodstream to where it is needed it needs some transport. For that, it uses low density lipoproteins (LDLs). However, it’s not a return journey, and to get back they must use another form of lipid known as a high density lipoprotein (HDL). The protein part is water soluble, wile the lipid part can attach to the cholesterol and carry it around the bloodstream.
The problem arises with free radicals, which are oxygenated molecules that are generated by the body’s metabolism, and also created from pollutants, such as pesticides and cigarette smoke, and the UV portion of daylight. These can oxidize the low density lipoproteins so that they can be attacked by phagocytes (while blood cells) deposited as plaques in the artery walls. This hardens and thickens the arteries, reducing the heart’s blood supply which in turn can cause strokes and heart attacks.
This can be prevented in a number ways, the major of which are by consuming plenty antioxidants in your food, mostly contained in phytochemicals (plant chemicals), reducing your LDL cholesterol levels to the minimum needed by your body, and also by increasing the HDL levels in your bloodstream by as much as possible.
Grapefruit pectin fiber can bind to cholesterol, and prevent it from being deposited in the artery walls by the oxidized LDL. A sixteen week double blind study (neither the subjects nor those carrying out the test and analyzing the results knew who were given the placebo) found that grapefruit pectin successful reduced the low density cholesterol level of 27 subjects by 10.8% and overall plasma cholesterol by 7.6%. These volunteers were at a medium to high risk of atherosclerosis due to a high LDL cholesterol concentration in their blood.
Animal studies have also been carried out, whereby animals were fed a high cholesterol diet, and those fed a high fat diet were found to have an average of 45% narrowing of their arteries, and those fed the same diet, but with added grapefruit pectin fiber, were found to have only 25% narrowing, thus corresponding with the results of the human volunteers.
It is essential that you maintain a stable level of sugar in your blood since the body reacts to low blood glucose by making you feel hungry, and thereby forcing you eat. If you are trying to lose weight you will find it very difficult if your blood sugar levels fluctuate. Grapefruit pectin can reduce the rate at which carbohydrates enter your bloodstream, and therefore the rate at which sugars are absorbed.
Studies have also indicated that pectin can even out your blood sugar concentration, so that you experience fewer fluctuations or sudden spikes that can make you feel either very hungry, and so binge on carbohydrates, or very satisfied so that you eat nothing at all. The maintenance of a stable level of glucose in the blood is necessary for a normal life since it is that that determine your need to eat food. If your blood sugar is low, the desire to eat high calorie carbohydrate food is uncontrollable.
This is the theory behind the so-called ‘grapefruit diet’. You eat a grapefruit prior to a meal, and allow it to be digested. The grapefruit pectin will make you feel full and so eat less, so that you can eat normal foods, but still lose weight. Many people take the grapefruit pectin in supplement form for its ease and economy of use. It is also more convenient since you don’t have to carry grapefruit around with you everywhere you go.
A Healthy Colon
Like any other soluble fiber, grapefruit pectin fiber is a dietary fiber that can help to maintain the health of your colon. In fact it is the only one of the basic four fibers of lignin, cellulose, hemicelluloses and pectin that is soluble. Although referred to as soluble, pectin softens and expands and provides substance and added weight to faeces in order to allow it to pass easier through your colon.
Other than ensuring the easy passage of your stool through your colon, and avoiding constipation, grapefruit pectin fiber can help to prevent excessive growth of bad bacteria in the intestine, and because it accelerates the passage of substances through the colon, there is less time for toxic or cancerous substances to be in contact with your bowel lining. It is that which causes bowel cancer, and grapefruit pectin fiber can help to prevent it.
Fiber can also help to prevent diverticulosis, where the intestinal wall develops small sacs and becomes weakened. It also prevents hemorrhoids, eases the symptoms of IBS (irritable bowel syndrome). In short, it offers many benefits for the health of your colon, and can help to cure many bowel conditions.
However, it is important that you don't just rush into using any form of dietary fiber, but take it gradually. You start with a small intake, and then increase it slowly; since it is not absorbed through the intestine too much can lie in your colon and ferment, causing any number of intestinal problems. When used properly it can ease the symptoms of irritable bowel syndrome, but if used to excess, or too quickly, can actually cause the same symptoms, in addition to blocking the absorption of essential minerals such as iron, zinc and calcium.
Grapefruit pectin fiber can do a great deal for health, including maintaining good blood sugar and cholesterol levels, and helping to keep your colon healthy. It is available in convenient supplement form, but make sure that you drink sufficient liquid each day in order to prevent the fiber blocking your intestine rather than allowing free passage of waste product into, through, and out of your colon.
October 02, 2008 09:36 AM
Cartilage has several roles to play in your body, an example of which is to form curved body parts that would otherwise be unsupported, such as the external contours of your ears or a large part of your nose. Without cartilage you ears and nose would flop around a lot, and it is also contained in the spine, to prevent your discs from grinding against each other.
However, the part that we are interested in is as a shock absorber between the bones of your joints. It allows bones to slide over one another without damage, either through friction or shock, and is also nature’s shock absorber, helping to support your weight while you are active. Thus, your cartilage protects from impact damage when you are running or jumping down from a height. This type of cartilage, known as articular cartilage, is bathed in a lubricating fluid known as synovial fluid, which introduces its own problems when your cartilage becomes damaged.
This damage can occur in several ways: as the result of a fall, for example, or direct contact with the joint when playing a physical contact sport such as football or soccer. It can also become damaged through wear and tear over a period of time, such with long distance runners or soccer players (again), and is also associated with age. Many years of continual use, especially amongst those with active rather than sedentary occupations, eventually lead to wear and damage.
Problems with the joint structure itself, known as osteoarthritis, can also damage the cartilage, as can being overweight for a lengthy period. You can also experience cartilage damage if you are bedridden or other wise immobile for long periods, because the cartilage needs regular movement to function correctly. This is connected with the blood supply, which will be discussed shortly.
Cartilage is constructed of cells known as chondrocytes that generate a fibrous matrix known as collagen, a mixture of amino acids known as elastin that allows the cartilage to return to its original shape after deformation, and non-collagenous matrix tissue containing proteins, water and proteoglycans that contain sulfated glycosaminoglycan chains. That last mixture is often referred to as ‘ground substance.’
One of the problems with cartilage is its lack of a direct blood supply, and it relies on the compression and decompression of the articular cartilage, or on the flexing of elastic cartilage, to create a pumping action that drives blood to the chondrocytes. This is why inactivity can cause cartilage damage, due to a lack of blood supply, and why it is repaired more slowly than other body components.
Once an injury or wear and tear damages a joint, the body’s natural defense, the immune system, is activated, and the major part of that involved in cartilage damage is the inflammatory response. The joint becomes inflamed, the quantity of synovial fluid is increased to provide more protection and swells the joint, and enzymes (hyaluronidase) are produced which, although part of the natural defense system, actually degrade the synovial fluid and the cartilage.
This increases the amount of inflammation and the process becomes self-perpetuating, leading to the condition known as degenerative joint disease (DJD) because the body is unable to produce enough glucosamine to generate the proteoglycan needed for repair.
This is where glucosamine sulfate enters the scene. Glucosamine is a precursor for glycosaminoglycans (GAG), which as mentioned as above are components of proteoglycans in the cartilage matrix ground tissue. It has been shown to stimulate the biosynthesis of proteoglycan, and analysis has shown its presence within articular cartilage after administering it orally to patients with cartilage disease. It therefore makes its way to the right place.
Glucosamine is administered in the form of glucosamine sulfate, the highly electrically charged sulfate groups believed to aid in the compression properties of cartilage. It is rapidly absorbed into the bloodstream, although only about a quarter of the oral dose is eventually available to the body, and high concentrations accumulate in the liver, kidneys and in articular cartilage where it is used in the biosynthesis of GAG.
When in solution, glucosamine sulfate separates into ions: sulfate and glucosamine. Glucosamine ions are involved in the synthesis of GAG, that then combine with proteins to form proteoglycans, a component of the non-collagenous matrix of the cartilage. Although glucosamine is the major active component, there is evidence that the sulfate group contributes the stability of the matrix of the connective tissue since the uptake of sulfate ions increases with the amount of glucosamine sulfate used.
Another consideration here is that sulfate is an important part of proteoglycans, and glucosamine sulfate promotes not only the synthesis of glycosaminoglycans, but also of proteoglycans in general. Glucosamine is also active in regenerating the lubricating properties of the synovial fluid, and in hindering the activity of hyaluronidase, the enzyme that breaks down the hyaluronic acid in the synovial fluid.
Some people find that glucosamine, taken either alone or in conjunction with chondroitin sulfate and/or methyl sulfonyl methane (MSM), is more effective than the non-Steroidal anti-inflammatory drugs (NSAIDs) used to reduce inflammation (e.g. Aspirin and Ibuprofen) and without the side effects of these substances. MSM contains dietary sulfur, which is necessary for cell structure and healthy cell repair. Methyl sulfone methane is know to be beneficial for painful conditions such as arthritis, and also improves the blood circulation. It might also play a part in helping glucosamine sulfate get to the site of the cartilage damage.
Glucosamine is a large molecule, however, and finds it difficult to make its way to the area around the joint due to the lack of a direct blood supply. It is therefore taken in relatively large doses to ensure that sufficient amounts get to where it is needed. Many people insist that glucosamine sulfate is very effective in reducing, or even eliminating, their pain, and it is finding increasing popularity in the treatment of arthritis and other conditions involving cartilage damage.
Hoodia Extract And Appetite
September 26, 2008 11:36 AM
Hoodia is a plant that belongs to the milkweed family and consists of about twenty different species. It is a leafless, spiny plant, with fleshy finger-like stems. Along the stems, there are rows of thorns, while the plant bears flesh-colored flowers. Flies are attracted to the flowers by the strong smell of decaying meat, causing the flies to lay their eggs and pollinate the flowers. Sometimes spelled hootia, hodia, hoodie, and hudia, hoodia has recently gained a great amount of attention in the United Kingdom and America after being featured on BCC and CBS. Often growing in summer rainfall areas in Angola, Botswana, Namibia, and South Africa, along with winter rainfall areas in Nambia, hoodia gordonii is the only species that contains the chemical component that suppresses appetite.
Hoodia has been used for thousands of years by San Bushmen, as it populates the arid territories of South Africa and Namibia. Because San Bushmen needed to remain active in order to survive, they had little need for dieting, but this plant provided them with stamina and a curbed appetite during long periods without food. Along with reducing or eliminating the desire for food, many people believe that hoodia also increases energy and can act as an aphrodisiac on the user.
The appetite-suppressing ingredient found in hoodia is a molecule that is similar to, but stronger than glucose. The active compound that was isolated to be responsible for appetite suppression is P57, which works by sending a signal to the hypothalamus of the brain, tricking the body into thinking that it is no longer hungry, and resulting in a complete lack of appetite. P57 is a Steroid like molecule that is chemically bonded to a chain of three sugar molecules. The appetite-suppressing and mood-enhancing properties of P57 go directly to the mid-brain, where it causes neuron cells to fire as if you were full.
The hypothalamus is the region of the brain that contains several important centers which control body temperature, thirst, hunger, water balance, and sexual function. Additionally, the hypothalamus is closely connected with emotional activity and sleep and also functions as a center for the integration of hormonal and autonomic nervous activity through the control of pituitary secretions. In short, the hypothalamus links the nervous system to the endocrine system. The pituitary gland is often thought of as the mater gland in our bodies, as the anterior and posterior pituitary secrete a variety of hormones that influence all cells and affect almost all physiological processes.
The pituitary gland is powered by the hypothalamus, as some of the neurons in the hypothalamus secrete the hormones that are responsible for controlling the secretion of hormones from the anterior pituitary. The inhibiting and releasing hormones of the hypothalamus are carried directly to the anterior pituitary where hypothalamic hormones bind to receptors on anterior pituitary cells.
The P57 hormone that is found in hoodia works by increasing the amount of ATP in nerve cells found in the hypothalamus. ATP is an energy-producing molecule that is formed from glucose. When there are increased levels of ATP in hypothalamic nerve cells, those nerve cells fire as if you had just eaten, even when you haven’t. Hoodia is a safe herb taken for hundreds of years, have you tried Hoodia lately?