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Learn how gotu kola reduces stress and anxiety Darrell Miller 2/21/19
Why people love CBD - the cannabis product that won't get you high Darrell Miller 1/19/19
Brewer's yeast, a potential probiotic? Darrell Miller 9/7/18
Here's How to Actually Remove Pesticides From Fruits and Vegetables Darrell Miller 6/4/18
Water Fluoridation Darrell Miller 10/13/17
Mice fed tryptophan develop immune cells that foster a tolerant gut Darrell Miller 8/13/17
In praise of turmeric, the magic yellow spice. Darrell Miller 3/23/17
Health Benefits OPC Grapeseed extract. Darrell Miller 12/17/16
Did you know that cinnamon can boost intelligence? Darrell Miller 11/1/16
Anemia Causes, Prevention And Supplements. Darrell Miller 8/7/14
Liquid Calcium Citrate - An Overview of What to Discover Darrell Miller 8/1/14
Dietary Protein Basics Darrell Miller 7/21/14
What Are The Benefits Of Ubiquinol Vs Regular CoQ10? Darrell Miller 5/31/14
Silica Supplements for Healthy Bones Darrell Miller 4/19/14
Is Beta Carotene The Safe Vitamin A? Darrell Miller 3/21/14
Xylitol, a Healthy and Safe Sweetener. Darrell Miller 3/12/14
The Health Benefits OF Avocado Oil Darrell Miller 3/8/14
Can Coconut Butter Lotion Really Help My Dry Skin? Darrell Miller 2/28/14
Can Coconut Butter Lotion Really Help My Dry Skin? Darrell Miller 2/28/14
Is Egg White Protein A Better Protein? Darrell Miller 1/24/14
What Is Beta Alanine And How Does It Improve My Athletic Performance? Darrell Miller 1/16/14
Does Beta Sitosterol Help Reduce Cholesterol? Darrell Miller 11/14/13
Does Ubiquinol Get Absorbed Better Than Regular CoQ10 Darrell Miller 11/6/13
The Amazing Health Benefits of Curcumin Darrell Miller 4/19/12
Can tea Tree Oil Kill Bugs? Darrell Miller 9/26/11
What is Bioperine and How Does It Help with Absorption of Vitamins Darrell Miller 4/21/11
How Does the Herb Holy Basil Help with My Health? Darrell Miller 3/10/11
Fight Free Radical Damage From Toxins With Vitamins And Herbs Darrell Miller 7/28/10
Vitamin A Vs Beta-Carotene and its Safety Darrell Miller 5/9/10
Milk Thistle And Silymarin Darrell Miller 8/12/09
Polyphenols is an Antioxidant Darrell Miller 10/13/08
DHEA Darrell Miller 8/15/08
Apple Cider Vinegar Darrell Miller 8/13/08
Can the Fatty Acid CLA Help me Lose Weight ? Darrell Miller 7/14/08
Multiple Vitamins Darrell Miller 6/11/08
Antioxidants For The Body Darrell Miller 6/10/08
Cranactin - Cranberry Extract Darrell Miller 5/21/08
Broken Cell Chlorella - Single Celled Micro alga Darrell Miller 4/21/08
Vitamin C Citations Darrell Miller 5/28/07
D-Ribose Powder Benefits! Darrell Miller 4/10/07
EpiCore Benefits Darrell Miller 4/9/07
How Does It Work? Darrell Miller 7/8/06
Scientific References Darrell Miller 2/11/06
Vitamin C FAQ's Darrell Miller 12/27/05
Carnitine Creatinate Darrell Miller 12/8/05
Immune Renew Fact Sheet Darrell Miller 12/7/05
Chloride: The Forgotten Essential Mineral Darrell Miller 11/20/05
Source Naturals - From Formula to Implementation Darrell Miller 8/20/05
Source Naturals - Continuous Quality Assurance Darrell Miller 8/20/05
MSM - Natures Primary Sources of Organic Dietary Sulfur Darrell Miller 8/2/05
THE FDA AND STEVIA Darrell Miller 7/15/05
THE FDA AND NON-CALORIC SWEETENERS Darrell Miller 7/15/05
HOW BIOAVAILABLE IS PYCNOGENOL? Darrell Miller 7/13/05
<B>SILYMARIN: LITTLE KNOWN ANTIOXIDANT</b> Darrell Miller 7/12/05
HAWAIIAN NONI (Morinda citrifolia) Darrell Miller 7/11/05
GREEN TEA EXTRACT - For Antioxidant Support Darrell Miller 6/29/05
CHITOSAN: The Fiber that Binds Fat Darrell Miller 6/25/05
Herbal Forms Darrell Miller 6/25/05
ENDNOTES Darrell Miller 6/23/05
Stomach Ulcers Darrell Miller 6/23/05
CLINICAL APPLICATIONS OF CAPSICUM Darrell Miller 6/23/05
Probiotics - Our Friendly Bacteria Darrell Miller 6/16/05
Allergy & Sinus Season: Healthy Lifestyle Tips Darrell Miller 6/9/05
Chem-Defense - Fight Chemical sensitivity ... Darrell Miller 6/1/05
Under-Reported (and Underappreciated) Cholesterol control. Darrell Miller 5/12/05




Learn how gotu kola reduces stress and anxiety
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Date: February 21, 2019 07:57 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Learn how gotu kola reduces stress and anxiety





Gotu Kola has been studied and found to increase calm and alertness by one hundred percent in human. After only 60 minutes post ingestion the effects are demonstrated and showed a noteworthy reduction in startle response. A starting dose is three cups of gotu kola tea per day. There are a broad range of other health benefits which include boosts in cognitive function. It was found just as effective as folic acid. Alzheimer patients have also seen an improvement in mood and memory via the compound called triterpenes. Gotu Kola improves circulation and inflammation as well as aiding in restful sleep.

Key Takeaways:

  • Gotu kola despite the name does not contain any stimulant like caffeine rather it is a relaxant herb that can be taken fresh or as a tea.
  • Gotu kola can be used in culinary practice as part of recipes and also as a medicine in alternative medicine.
  • Gotu kola has a lot of health benefits which include being used to treat mental fatigue, depression, memory loss, and insomnia.

"Gotu kola is a popular herbal remedy that has a long history of being used in Ayurvedic medicine due to its healing properties that can promote mental and emotional health."

Read more: https://www.naturalnews.com/2019-01-15-learn-how-gotu-kola-reduces-stress-and-anxiety.html

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Why people love CBD - the cannabis product that won't get you high
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Date: January 19, 2019 10:48 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Why people love CBD - the cannabis product that won't get you high

The CBD market is booming after the recent legalization of marijuana in many states. CBD is short for cannabidiol which is a compound found in cannabis and hemp plants. It is not a psychoactive- you do not get high from ingestion. It is commonly used to treat anxiety and insomnia. Further studies are being conducted to research its efficiency against arthritis and epilepsy. CBD is normally extracted into an oil or cream, but can be sold in a variety of products.

Key Takeaways:

  • There are plenty of states now that are making the smoking of weed completely legal.
  • Many old school individuals still feel that anything related to cannabis should not be legalized.
  • People really do like CBD because it has the same effects as weed without getting you truly high.

"So, what exactly is CBD — and why are you able to get your hands on it even if you don't live in a state where cannabis is legal?"

Read more: https://www.cnbc.com/2018/11/09/what-is-cbd-these-popular-cannabis-products-wont-get-you-high.html

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Brewer's yeast, a potential probiotic?
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Date: September 07, 2018 10:52 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Brewer's yeast, a potential probiotic?





Brewer's yeast, a potential probiotic?

Probiotic is current trend amongst consumers and are increasingly popular for their health benefits.brewers yeast is an essential commodity for making bread and beer.A study reveals brewers yeast tolerant to various temperatures high concentration of bile salt and sodium chloride gastric juice, intestinal environment, alpha-amylase, trypsin, and lysozyme,it produces organic acids and exhibits resistance against drugs.brewers yeast can absorb cholestrol and can also produce killer toxins and also demonstrated better antibacterial activity against gram-negative bacteria than gram-positive.brewers yeast also produces enzymes that enhance nutrient utilisation in the gut.

Key Takeaways:

  • A study concluded that brewer’s yeast can be considered a probiotic of which yoghurt and kimchi are one.
  • Brewer’s yeast can produce organic acids, killer toxins and absorb cholesterol. It has the ability to produce enzymes such as amylase for gut nutrient utilization.
  • Some of the health benefits of brewer’s yeast which is used in beer and bread are that it improves blood sugar and fights against cancer.

"Ingestion of brewer’s yeast was also considered safe as it did not cause any toxic side effects based on the results of toxicity tests."

Read more: https://www.naturalnews.com/2018-08-11-brewers-yeast-a-potential-probiotic.html

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Here's How to Actually Remove Pesticides From Fruits and Vegetables
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Date: June 04, 2018 01:16 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Here's How to Actually Remove Pesticides From Fruits and Vegetables





Pesticide residue now commonly occurs on all fresh produce (including organic produce which uses natural pesticides). Those who believe pesticide consumption is directly linked to serious diseases like cancers can follow four at-home tips to drastically reduce the ingestion if pesticides. These include rinsing with water, soaking in a vinegar solution and then rinsing with cold water, using a rinse or spray made by combining water and baking soda, lightly boiling the produce, or removing the outer skin or peel even after rinsing.

https://www.youtube.com/watch?v=Hh5RWjaRKpY&rel=0

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Water Fluoridation
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Date: October 13, 2017 10:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Water Fluoridation





Water Fluoridation is adding fluoride to water. The United States puts fluoride in over 70% of their water supply. This is most of any country by far. Putting fluoride into water was first implemented to help with dental issues. Scientists are now starting to realize the harmful effects of fluoride. Fluoride is a poison. Especially since the benefit of fluoride comes from topical use, not from ingesting. Communities all over the United States are now starting to realize the harmful effects of fluoride. Fluoride is outdated and unnecessary.

Key Takeaways:

  • When used to prevent disease fluoride acts as a drug.
  • Fluoride’s biggest benefit comes from contact with the teeth. You do not need to swallow fluoride.
  • Fluoridation is causing children to have a discoloration of the teeth.

"The most obvious reason to end fluoridation is that it is now known that fluoride’s main benefit comes from topical contact with the teeth, not from ingestion."

Read more: http://fluoridealert.org/issues/water/

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Mice fed tryptophan develop immune cells that foster a tolerant gut
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Date: August 13, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Mice fed tryptophan develop immune cells that foster a tolerant gut





Tryptophan is a fundamental building block of protein. A study was conducted on genetically identical mice that were separated and raised in different environments, which led to the finding that environmental factors were a high contributor in regards to developing an immunity to irritable bowel disease. Bacteria highly affects the immune system because the mice that were raised in sterile conditions grew the immune cells. Doctor Luisa Cervantes-Barragan conducted the study. Tryptophan is common in both mouse and the human balanced food diet.

Key Takeaways:

  • Tryptophan ingestion in mice leads to formation of micros that fight IBS
  • Humans suffering from IBS can benefit diets high in tryptophan
  • Foods high in protein such as eggs , chocolate, and cheese have these compounds.

"People have the same tolerance-promoting cells as mice, and most of us shelter L. reuteri in our gastrointestinal tracts."

Read more: https://medicalxpress.com/news/2017-08-mice-fed-tryptophan-immune-cells.html

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In praise of turmeric, the magic yellow spice.
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Date: March 23, 2017 02:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: In praise of turmeric, the magic yellow spice.





For those who pursue optimum health, Turmeric is a spice that should not be overlooked. Turmeric boasts a myriad of wonderful health benefits including it's anti-inflammatory and anti-cancer properties. Turmeric can be added to a great many meals and can also easily be added to smoothies if you want to find ways to incorporate it into your diet. Read on to find out more creative uses of turmeric, and how to make it more easily absorbed in the body.

Key Takeaways:

  • A study attributed Japan's residents life span has increased due to the ingestion of tumeric 3 times a day
  • Curcumin is the key compound of tumeric and this is where it's healing powers are derived from
  • The preferred way, is to use in a smoothie or brew w/ tea. Also, black pepper will mask the odd 'taste'. Studies show it helps with headaches, IBS & prevention /treatment of cancer.

"The magic is in the Curcumin which is the potent compound within turmeric."

Read more: https://www.lorrainepascale.com/in-praise-of-turmeric-the-magic-yellow-spice/

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Health Benefits OPC Grapeseed extract.
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Date: December 17, 2016 02:48 AM
Author: Darrell Miller
Subject: Health Benefits OPC Grapeseed extract.

The grape seed concentrate is prevalent and sought after worldwide for all the great reasons for health purpose. It strengthens and secures the body cells and the blood vessel and venous dividers, boosts muscle repair and prevent inflammations . It likewise can shield the cardiovascular framework from free radical harms, therefore encouraging the bringing down of terrible cholesterol. What is grape seed extricate, you may inquire? It is a characteristic plant segment that is extricated from sound entire grape seeds that are lavishly thought with OPC's and other effective cancer prevention agents.

The grape seed concentrate is likewise known to encourage would mending. Customary societies utilized grape seed separates, nearby pine bark concentrates to dress injuries. Avoiding osteoporosis, tooth rot, and skin malignancy are some different advantages of seed concentrates. Grape seed concentrates are abundantly favored than different cancer prevention agents since they has demonstrated to contain 50 times more cell reinforcement powers contrasted with Vitamin E and C.

The grapeseed concentrates are likewise known to enhance the mind wellbeing, skin wellbeing and great vision. It is ostensibly the main cancer prevention agent that can wind and invade the blood hindrance which permits it to protect the nerve and cerebrum tissue. The skin extricate then again contains quercetin, anthocyanidins, catechins, flavonols, polyphenols like resveratrol, and OPC's.

These concentrates are promptly accessible as resveratrol supplements in the market today. They are sold in type of cases, pills, and the preferences and contain resveratrol in high focuses. The measurements for these supplements will vary contingent upon every person and the goal of utilizing them. Regardless of the type of these supplements, ingestion is the thing that matters most. They bear few to no reactions, few as in somebody susceptible to grapes may have an issue. Be that as it may, quality supplements should not to stress you since they've been "modified" for every individual.


Related Products

021078019664

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Did you know that cinnamon can boost intelligence?
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Date: November 01, 2016 06:09 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Did you know that cinnamon can boost intelligence?

cinnamon has a flavor that you either love or you hate. If you happen to be someone that enjoys the taste, you're in luck! did you know that cinnamon consumption may work to boost your intelligence? The next time someone questions how smart you are, pull out the cinnamon and thank them for noticing!

Key Takeaways:

  • Researchers have found that consuming Cinnamon might enhance learning skills.
  • Scientists at Rush University Medical Center in Chicago found that increased ingestion of cinnamon significantly improved the memory of "poor learning" mice.
  • When they tested the mice again after one month of cinnamon feeding, the researchers found that the mice determined to be poor learners had significantly improved their memory and learning skills. They could find their target hole twice as fast.

"Scientists at Rush University Medical Center in Chicago found that increased ingestion of cinnamon significantly improved the memory of "poor learning" mice."



Reference:

//www.naturalnews.com/055813_cinnamon_intelligence_Parkinsons_disease.html

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Anemia Causes, Prevention And Supplements.
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Date: August 07, 2014 05:22 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Anemia Causes, Prevention And Supplements.

foord for anemiaWhat is an anemia?

Anemia is the most widely recognized issue of the blood. It is a condition in which the blood is: inadequate in red platelets or lacking in hemoglobin. Both of these conditions can result in an absence of oxygen to be conveyed to all parts of the body. Bringing about symptoms, for example, weakness, frosty hands, loss of voracity, whiteness and shortcoming. Below are illustration of causes of anemia, prevention measures and iron supplements that can help.

Causes of anemia

Causes include loss blood, unreasonable destruction of red platelets or inadequate creation of red platelets.

Insufficient creation of red platelets is the most widely recognized class of pallor, and poor sustenance is the most well-known reason. The most successive sorts of supplement inadequate sickness are those identified with an insufficiency of iron, folic corrosive (vitamin B9), copper or vitamin B12.

Iron insufficiency pallor is frequently seen in babies more youthful than two years of age, adolescent young ladies, pregnant ladies and the elderly. This kind of weakness incorporate elements connected with poor dietary admission of iron, an expanded requirement for iron, diminished iron assimilation, blood misfortune or a consolidation of these circumstances.

Folic corrosive is the most as often as possible discovered vitamin lack on earth. The gatherings of individuals well on the way to have folic corrosive insufficiency are dipsomaniacs, individuals with mal-ingestion conditions or perpetual loose bowels and pregnant ladies. A folic corrosive insufficiency can likewise cause despondency, the runs and a swollen, red tongue.

Copper inadequacy is exceptional, be that as it may, it can happen in individuals who take a zinc supplement without expanding their copper admission in light of the fact that zinc can meddle with copper ingestion.

anemia symptomsHow to prevent anemia?

To avoid you have to consume overall adjusted dinners including iron rich nourishment. In the event that you have weakness, keep away from refreshments and sustenance holding juice, it meddles with the body's capacity to ingest iron. Maintain a strategic distance from tannins, they additionally hinder iron ingestion and nourishment high in oxalic acids; which incorporate almonds, asparagus, beans, beets, cashews, chocolate, kale and rhubarb.

While most instances of pallor are created by straightforward nourishment lacks, it can additionally be an indication of a more genuine restorative issue. The best way to get a clear judgment of sickness is to get a blood test. In the event that you think you have iron deficiency, don't start a supplement program until you have a finding from your doctor.

Supplements

Iron - helps avert iron insufficiency weakness. Take 30 milligrams fumarate, gluconate or succinate press twice a day between dinners. In the event that this reasons stomach trouble, switch to 30 milligrams with suppers three times each day.

Folic corrosive (vitamin B9) - aides anticipate iron deficiency brought about by folic corrosive inadequacy. Take 800 to 1,200 micrograms three times every day.

Vitamin B12 - aides anticipate vitamin B12 inadequacy pallor. Take 2,000 micrograms sublingual (set under the tongue) three times every day for 30 days, then 1,000 micrograms methylcobalamin (the dynamic type of B12) once a day, in addition to folic corrosive.

Vitamin C - helps the body assimilate iron. Studies have demonstrated that you can almost twofold your ingestion of iron from plant sources by devouring vitamin C with the iron. Take 1,000 milligrams 3 times each day with dinners.

Vitamin B5 (pantothenic corrosive) - assists with the creation of red platelets. Take 100 milligrams every day.

Vitamin B6 (pyridoxine) - assists with the creation of red platelets. Take 50 milligrams 3 times each day.

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Liquid Calcium Citrate - An Overview of What to Discover
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Date: August 01, 2014 05:29 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Liquid Calcium Citrate - An Overview of What to Discover

calcium foodsCalcium

While calcium is quite effective in conditions of improving health, it is valued very little without the addition of magnesium. Calcium in liquid type is much, much more potent than that of the tablet selection.

Absorption of calcium

Due to the fact liquid calcium is drinking water centered, it is virtually a single hundred % to be absorbed by the body. The reality of the subject is that much less than twenty five % of tablet based calcium is absorbed by the body.

Protein prosperous meals like meat cause calcium to be wasted via the urine. Calcium that is obtained from foods and the capsule type of calcium are badly absorbed. This suggests that most individuals are finding a lot significantly less calcium than they would like to believe is the scenario. As liquid ionic calcium is water primarily based, it is absorbed instantly. This ensures the physique the appropriate quantity of calcium.

It is extremely hard to get the optimum calcium needed for the entire body. This helps make it even far more motive for 1 to take calcium in liquid format relatively than tablet format.

calcium absorptionBenefits of liquid calcium

The digestive process rewards immensely from liquid calcium magnesium. It is excellent for the relief of constipation, indigestion and heartburn. It gains the digestive procedure in other strategies as well and for greatest outcomes, it ought to be taken right after eating.

The production of milk in lactating females is enhanced by the ingestion of calcium. Contractions through labor are also facilitated by calcium. Other advantages are that nerve impulses are regulated and taking calcium enables the clotting of blood.

Calcium deficiency

It is a properly-recognized truth that insufficient quantities of calcium trigger osteoporosis. Calcium deficiency has dire penalties for little ones as it can lead to rickets in kids. Far more important in adults, it causes softening of the bony tissue. This is acknowledged as osteomalacia.

It has been even more reported that the substantial blood pressure and cancer of the colon have also been attributed to insufficient quantities of calcium.

Symptoms of calcium deficiency

An individual can detect a lack of calcium in the body by the presence of tingling and or numbness all around the mouth and the fingertips. Calcium deficient persons will also knowledge painful aches and muscle spasms.

Lack of calcium can be a contributing aspect to currently being obese. It can also retard the method of losing extra fat. It has been uncovered that when a single eats also very little the human body stores all it can, as it does not know when following it will be fed. The identical course of action comes about when the body is starved of calcium.

There is a hormone in the entire body known as calcitriol. This has the power to constrict the arteries. Calcium regulates this hormone. Because of this approach, people today with high blood pressure will notice a drop in the blood strain when ingesting optimum ranges of calcium. Taking calcium also safeguards the nervous technique and the heart.

The system is equipped to create vitamins, but the same are not able to be stated about minerals. For top rated-degree overall health, the entire body involves satisfactory if not abundant amounts of food grade minerals, mainly calcium.

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Dietary Protein Basics
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Date: July 21, 2014 05:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Dietary Protein Basics

proteinDietary Protein Basics

You certainly stay an active life much like everybody else does today. When you are like many people, you could use some basic suggestions that are super easy to adhere to enhance your diet plan and nutrition. This short article contains some nutrients ideas that are easy to include in your every day routine.

The majority of people assume that ingesting fatty foods will result in bad health. In fact, your body needs fat to operate. Several food products, which can be rich in extra fat, for example cheese or avocado, are in reality quite healthful when ingested sparingly each day. So long as you consume in moderation and get away from unhealthy fats, you do not need to be concerned.

One thing many people believe is the fact diet is all about food. You should also consider how your body uses the food you eat. You desire to actually regularly physical exercise or even consume the right sorts of meals, your whole body will be grateful for this.

Reduce your sea salt ingestion. Most junk foods act like junk foods in terms of sodium information. When you can decrease your sodium absorption in what you eat, you may realize that you easier observe its flavoring developing. Unhealthy food will instantly style too salty for your needs. You won't have as many desires on their behalf.

Protein needed in your body

The minimum daily protein requirements as set by WHO(world health organization) are 0.8 grams per kilogram of body weight, however individual protein needs are dependent on one's level of activity, overall health status, and age. People dealing with injury need additional health proteins pertaining to structure curing. Athlete’s education hard to get muscle mass or which could possibly be creating tiny accidental injuries also requires additional pertaining to progress along with restoration. Protein desires in youngsters change from infancy right through to delayed teenage years, along with considerable amounts connected with new health proteins structure being made while in quick progress spurts. The particular health proteins demands and then secure the moment early adulthood is reached.

 

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What Are The Benefits Of Ubiquinol Vs Regular CoQ10?
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Date: May 31, 2014 06:33 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Are The Benefits Of Ubiquinol Vs Regular CoQ10?

fruits and vegetables Nutritional Supplement

In modern society, nutritional supplements have become a common method to improve health. A wide range of specific needs determines the use of different supplements, but there are a few that will work in just about everyone and improve their health.

What is a CoQ10

Coenzyme Q10, commonly abbreviated to CoQ10, is one of those universally effective supplements. This vitamin-like substance offers far-reaching benefits for the human body. It has a crucial role in the body's energy maintenance and it's an extremely powerful antioxidant. This substance is naturally produced by the body, but as we get older, the organism's ability to synthesize CoQ10 weakens progressively. It is, therefore, recommended that people initiate a regular intake of CoQ10 somewhere at the adult or even young adult life stage. This is a commonly prescribed supplement for old people owing to its longevity and energy inducing benefits, but it's especially critical for those who are medicated with statin drugs because these are known to reduce CoQ10 levels in the organism. Elite athletes can also benefit from this substance to achieve higher peak power levels.

CoQ10 supplement is available in two forms: fully oxidized (Ubiquinone) and fully reduced (Ubiquinol).

What is an Ubiquinol

Ubiquinol is the most efficient way to take advantage of this supplement because it's the fully reduced form of CoQ10 that our body actually absorbs and uses. The consumption of Ubiquinone requires our body to firstly metabolize and convert it into Ubiquinol. This process limits the speed and efficiency of CoQ10 absorption, requiring larger quantities to be consumed for similar health effects, not to mention that the metabolism has a tendency to worsen with age. Ubiquinone is more widely available and is cheaper, though.

It is usually recommended for people around the age of 35 - 40, to start taking Ubiquinol instead of Ubiquinone. This is when the efficiency of Ubiquinol eventually compensates its higher price tag over Ubiquinone. Turning the ingestion of CoQ10 supplement into a habit is one of the best ways to potentiate a long and healthy life.

Sources:

  1. en.wikipedia.org/wiki/Ubiquinol
  2. en.wikipedia.org/wiki/Coenzyme_Q10#Biosynthesis
  3. articles.mercola.com/sites/articles/archive/2013/11/03/coq10-vs-ubiquinol.aspx
  4. www.bodybuilding.com/fun/coq10-ubiquinone-ubiquinol-whats-the-difference.htm
  5. www.ncbi.nlm.nih.gov/pmc/articles/PMC3661336/

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Silica Supplements for Healthy Bones
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Date: April 19, 2014 05:36 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Silica Supplements for Healthy Bones

Silica

bonesFor a long lasting, the part of silica in the body was not known. Right away, it is around the paramount minerals. It can luckily be found in the vast majority of the vegetables and apples and oranges. Analysts have named silica as of late into the class of the most essential minerals for the body. Nutritionists assess that a grown-up might require 20 to 30 mg for every day.

Health benefits of silica

This mineral helps the body to develop the bones, the teeth, the cartilages, the tendons and the hair, giving further safety. Silica additionally gives the skin suppleness and the vascular dividers versatility. An eating regimen rich in silica can avoid osteoporosis, atherosclerosis (thickening of blood vessel dividers), skin wrinkling, diminishing and balding, broken nails and tooth rot. It makes the teeth, the nails and the hair to sparkle. Silica exists in lung tissue, so it is prescribed for the re-mineralization handle in tuberculosis patients. Since it serves to develop bone and cartilage, this mineral must not be absent from the eating methodologies of pregnant women and kids experiencing rickets. Additionally it helps acclimatize phosphorus, which is exceptionally imperative for the cerebrum wellbeing.

Silica sources

Luckily, silica is found in numerous nourishments we consume regularly, and particularly in leafy foods. A percentage of the wealthiest sources are the entire grains, the pieces of fruit and oranges, lemons, grapes, raisins, almonds, peanuts, nuts, grains by and large, cabbage, carrots, squash, green beans, cucumbers, mushrooms, onions, leeks, parsnips, weeds and radishes. From these, the entire grains hold a type of silica, which is not difficult to absorb. Corn shelled and results of it (white bread, for instance) do not hold silica. Besides, all refined or prepared items lose their supplements, including silica. Lager and nectar have additionally a substantial amount of this mineral in their creation. It exists even in water in diverse amounts, depending from on the land zone. Around the creature sustenance sources, fish is the particular case that holds silica. Since the nourishments holding this mineral are such a large number of, we can give our body, for the most part without issues, the everyday necessity. Silica lack is uncommon. It happens in individuals who consistently consume foods grown from the ground and the elderly, because the mineral is more troublesome to absorb with age.

The vicinity of silica in the body is exceptionally imperative. The mineral is fundamental for calcium ingestion especially in the early phases of bone development, additionally for supporting skeletal wellbeing all around life. It is included in framing collagen and that is the reason it is vital for the strength of nails, skin and hair. Silica is additionally important to keep the adaptability of corridors, and assumes a real part in averting cardiovascular illnesses. It animates the insusceptible framework and deferrals the maturing procedure of tissues. The level of this mineral in the body diminishes with age. In this way, more seasoned individuals require a higher admission of silica, contrasted with ones that are more youthful.

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Is Beta Carotene The Safe Vitamin A?
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Date: March 21, 2014 02:29 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Is Beta Carotene The Safe Vitamin A?

vitamin a squashWhat is beta carotene

Beta Carotene is a capable pwerful antioxidant that is useful for the heart and circulatory. In the constitution, it is changed into Vitamin A for the support of solid skin, great vision, and a strong immune system. Vitamin An is fundamental for ordinary structure of epithelial cells that ensures the form from ecological defilement.

Profits of Beta Carotene

Beta Carotene is accommodating with keeping the hardening/thickening of the corridor dividers (dissimilated sclerosis). It additionally helps lessen blood cholesterol.

Beta Carotene might likewise be accommodating in the medicine of AIDS, waterfalls, macular degeneration, and leukoplakia. It additionally may be advantageous in activity impelled asthma, growth, coronary illness, hypertension, Alzheimer's sadness, migraines, and rheumatoid joint pain.

Beta carotene has been said that it may ensure against malignancy and coronary illness. These profits are said to be because of its capacity to help the insusceptible framework and act an influential cell reinforcement inside the human form. Cell reinforcements kill free radicals, which are very receptive compound substances that can harm inner unit structure and encompassing material. This can prompt maturing and untimely ailment.

Beta Carotene is a compelling cell reinforcement that is valuable for the heart and circulatory. In the physique, it is changed into Vitamin A for the support of sound skin, great vision, and a solid invulnerable framework.

Vitamin An is key for ordinary structure of epithelial units that secures the form from ecological pollution.

It helps in the counteractive action of night visual deficiency and xerophthalmia, and in the field of dentistry, finish hypoplasia or lack of the tooth lacquer. It likewise anticipates different skin issue, improve resistance and ensures the figure from different contaminations.

Since carotenes are fat solvent, they ought to be consumed with fats to advertise more stupendous ingestion of carotene in the physique. Cooking the sustenance for a couple of minutes until the cell divider breaks to permit the shade to blend with the fluid is an alternate variable that incredibly helps the retention of this significant substance in the body.

Sources

  1. //ezinearticles.com/386397

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Xylitol, a Healthy and Safe Sweetener.
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Date: March 12, 2014 09:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Xylitol, a Healthy and Safe Sweetener.

What is xylitol

Xylitol is a comprehensively utilized regular sweetening operator that was initially uncovered by a German Chemist in the nineteenth century. The primary crude materials utilized for its assembling are birch trees and corn, however can moreover be processed from plums and berries. It is worth specifying that it is in addition commonly handled in little amounts by the human form. Xylitol is without a doubt not the most well known sugar substitute or nourishment added substance yet that doesn't imply that it isn't an essential one since it pushes various health profits. Researchers began investigating these profits once again a large portion of a century prior and more conceivable solid profits are continuously investigated today. Artificially it is a sugar liquor that has five carbon iotas in its compound structure and this structure is answerable for a large portion of its properties that make it gainful.

Benefits of xylitol

As we specified, xylitol has various profits, yet the particular case that is best thought about is the way that it can avoid dental caries. Research discoveries are strong to the point, that this profit is undeniable. There are numerous instruments that are answerable for this valuable impact. One of them is that dissimilar to sugar and starchy sustenances it doesn't result in an abatement of the ph in the mouth, despite what might be expected it can help kill it. Acidic conditions in the oral pit are valuable for microorganisms like S. Mutans that are the primary driver of dental caries. Moreover, the acids processed can bring about harms to the tooth veneer that ensures our teeth. Other than securing tooth veneer, there are proof that propose it can additionally help restore it. Notwithstanding that, these microorganisms can't age xylitol to handle vitality so as to duplicate, then again sugar is their favored vitality source. At long last, xylitol can extraordinarily diminish the adherence of the organisms on the tooth surface and as a result their capacity to manufacture plaque. All the reasons above help xylitol's tooth day battling profits.

An audit of the experimental writing shows that xylitol conceivably pushes various other health profits. Most importantly it is a low calorie sweetener, having very nearly 40% fewer calories contrasted and table sugar. Notwithstanding that it has a low glycemic record and in this way it could be utilized by diabetics as a sweetening operator without having the alarm of a sudden blood glucose increment. One more profit that has been as of late found from creature studies is that it can build bone mass and the mineral substance of bones. An alternate potential profit is that it can help control candida as has been indicated for the most part by in vitro studies. At long last, there are confirmation that recommend that it can avoid contaminations, for example, Acute Otitis Media in youngsters. In the event that to this you include the way that it has a comparative taste with sugar with no metallic or other trailing sensation it would appear to be one of the best options to sugar.

Other benefits of xylitol

It has been made clear that xylitol has various vital profits. On the other hand, it is paramount to note that it has several minor reactions also. The two fundamental symptoms that could be created by the utilization of xylitol are bloating and looseness of the bowels. These symptoms are created on the grounds that xylitol is ingested by inactive dispersion and happen assuming that somebody expends it above his laxation limit. It is likewise worth noting that the laxation limit can expand over the long run as the physique adjusts to the routine ingestion of xylitol. A couple of extra symptoms like unfavorable susceptibilities have been accounted for however they are not decently archived or affirmed via research information. At long last, most official associations, including the FDA have sanction it as a safe nourishment added substance for people.

Dissimilar to people, xylitol is not alright for pooches and it can bring about serious hypoglycemia and harms to your canines liver that can even prompt passing if untreated. So determine you keep all xylitol holding items far from your canine.

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The Health Benefits OF Avocado Oil
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Date: March 08, 2014 09:02 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Health Benefits OF Avocado Oil

avocado fruitBenefits of avocado

Avocado oil has a high attention of healthier fats and supplement E, that is a fabulous epidermis lotion. Icy pressed virgin avocado oil, taken consistently, may help decrease levels of cholesterol and ensure against coronary illness.

Clearspring regular Avocado oil is icy pressed from oil-rich green olives and is broadly distinguished for its wellness profits notwithstanding a support to excellence.

Foul avcado oil is recognized to be a standout amongst the most restorative vegetable oils one can consume. It is a multi-reason oil that could be utilized for culinary purposes suitable for dressings and sauces and singing, because of its high smoke purpose of over 490 degrees. Natural avocado oil is additionally a top notch "transporter" oil for different qualities; avocado bearer oil is perfect for implantation with different herbs. Notwithstanding its suitability as an edible, foul avcado oil is additionally top notch for utilization as a corrective and the repair of harmed skin.avocado bearer oil is fine for making diverse seasoned oils. Despite the fact that fine for people and different primates, natural avocado oil holds a fattening corrosive known as persin, which might be profoundly poisonous to local creatures, especially pooches, felines and stallions.

This offers no issues to your general health or that of your skin, and holds a monounsaturated oil utilized within fragrance based treatment. There is nothing else in avocado oil with the exception of the 30% of oil that the foods grown from the ground holds. You can drink it without it doing you hurt. An engineered proportionate to avocado oil might fill the mark with included chemicals: one or more to enhance skin ingestion, some to protect the oil from oxidation (despite the fact that it holds its own particular cancer prevention agents), emulsifiers and surfactants to help it spread better (an oil?).

Avocado content

Actually avocado oil holds its own particular emulsifier, lecithin, and additionally the cancer prevention agents Vitamin An and Vitamin E that likewise help to administer a young looking skin. These cell reinforcement vitamins annihilate the free radicals that execute your skin cells and make you look more advanced in years. Avocado oil can help you to continue looking more youthful as you develop sequentially more senior. It likewise holds vitamin D that is so paramount in large portions of the natural methodologies inside your skin - it is not called the 'daylight vitamin' to no end.

Cell reinforcements secure you from the impacts of the less than great UV radiation held in solid daylight, the free-radical producing pesticides, activity and modern outflows and tobacco smoke. Without some type of cell reinforcement medicine your skin would quickly wrinkled and develop old as its unit films are burst and annihilated. Vitamins An and E execute off the free radicals that cause this.

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Can Coconut Butter Lotion Really Help My Dry Skin?
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Date: February 28, 2014 11:22 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Coconut Butter Lotion Really Help My Dry Skin?

Benefits of coconut  lotion to skin

One of the best lotions for all skin sorts, particularly dry, is coconut oil. It is determined from ready coconut meat and is utilized for cooking and as a grease, frequently for the skin. There may even be a few profits from the ingestion of characteristic coconut oil. Assuming that you are searching for coconut oil salve, there are numerous spots to discover it. You may run into it on the racks of health sustenance or entire nourishment stores. There are numerous online retailers who offer high quality coconut oil. Likewise numerous tanning moisturizers are enhanced with coconut oil. For issue territories like feet and heels, slip on cotton socks in the wake of saturating. Likewise, saturating straightforwardly in the wake of showering while skin is still sodden can help secure dampness.

Characteristic of coconut lotion

There are other characteristic lotions that you may need to think about also. Olive oil cream is getting to be progressively mainstream, as is the utilization of additional virgin olive oil on its own for skin and hair saturating. Olive oil might be utilized in the wake of showering or as a hot oil medicine for dry hair. An alternate top part is shea margarine. Shea spread is determined from shea tree products of the soil prized for its humectant lands, which is the reason you'll discover shea margarine moisturizer, cream and different items.

In some cases you'll discover mixes of different saturating fixings like coconut oil and shea margarine joined together with a cooling element like cucumber. The scent of cucumber is exceptionally invigorating and the lands of this vegetable are extremely cooling. Cucumber moisturizer is extraordinary for sleek skin, feet and hands. You'll discover no lack of cucumber melon fogs and creams as this scent mixture was taken to notable status by the organization Bath and Body meets expectations, producing numerous copycats.

As should be obvious, coconut oil moisturizer is only one of the numerous lotions you can use on dry skin. You may need to utilize a mix that holds all the significant creams, for instance coconut oil, shea margarine, olive oil and different elements like vitamin E. Form spreads produced out of shea spread, cocoa margarine and avocado are perfect for super dry skin. They have a consistency like margarine, are warmed between the palms and connected to the skin for ultra hydration. If you favor salve, cream, or form spread what's essential is that you are normally saturating the skin on your physique to keep it delicate and supple.

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Can Coconut Butter Lotion Really Help My Dry Skin?
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Date: February 28, 2014 11:22 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Coconut Butter Lotion Really Help My Dry Skin?

Benefits of coconut  lotion to skin

coconut treeOne of the best lotions for all skin sorts, particularly dry, is coconut oil. It is determined from ready coconut meat and is utilized for cooking and as a grease, frequently for the skin. There may even be a few profits from the ingestion of characteristic coconut oil. Assuming that you are searching for coconut oil salve, there are numerous spots to discover it. You may run into it on the racks of health sustenance or entire nourishment stores. There are numerous online retailers who offer high quality coconut oil. Likewise numerous tanning moisturizers are enhanced with coconut oil. For issue territories like feet and heels, slip on cotton socks in the wake of saturating. Likewise, saturating straightforwardly in the wake of showering while skin is still sodden can help secure dampness.

Characteristic of coconut lotion

There are other characteristic lotions that you may need to think about also. Olive oil cream is getting to be progressively mainstream, as is the utilization of additional virgin olive oil on its own for skin and hair saturating. Olive oil might be utilized in the wake of showering or as a hot oil medicine for dry hair. An alternate top part is shea margarine. Shea spread is determined from shea tree products of the soil prized for its humectant lands, which is the reason you'll discover shea margarine moisturizer, cream and different items.

In some cases you'll discover mixes of different saturating fixings like coconut oil and shea margarine joined together with a cooling element like cucumber. The scent of cucumber is exceptionally invigorating and the lands of this vegetable are extremely cooling. Cucumber moisturizer is extraordinary for sleek skin, feet and hands. You'll discover no lack of cucumber melon fogs and creams as this scent mixture was taken to notable status by the organization Bath and Body meets expectations, producing numerous copycats.

As should be obvious, coconut oil moisturizer is only one of the numerous lotions you can use on dry skin. You may need to utilize a mix that holds all the significant creams, for instance coconut oil, shea margarine, olive oil and different elements like vitamin E. Form spreads produced out of shea spread, cocoa margarine and avocado are perfect for super dry skin. They have a consistency like margarine, are warmed between the palms and connected to the skin for ultra hydration. If you favor salve, cream, or form spread what's essential is that you are normally saturating the skin on your physique to keep it delicate and supple.

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Is Egg White Protein A Better Protein?
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Date: January 24, 2014 09:48 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Is Egg White Protein A Better Protein?

egg whiteEgg White a Protein?

You may have been continually hunting down the best protein supplement so as to go down your quality preparing muscle schedule. Here is an incredible and modest proposal for you “Egg White”. You can consume to the extent that you like. There is no specific threat for your health. On the other hand, recollect simply the egg white and not the entire egg.

Every one holds no less than 4- 6gm of unadulterated protein. You blend each morning in the shaker four egg white's line with half a spoon of cocoa, simply to enhance the taste of it. That is 20- 25gm of unadulterated protein. It is the protein admission sum you get from one bit of a protein rich supplement. Some individuals can't oversee swallowing crude egg whites. It simply won't go down. In the event that that is the situation attempt to heat up the eggs and expend the bubbled egg white. You might prescribe completing this once a day. Specifically, in the wake of getting off the cot is the perfect opportunity to accomplish better ingestion from the muscle units.

All things considered you surely not saying that it ought to be a substitute for protein shakes or amino acids supplements. It is equivalent in protein quality to the protein supplements. Along these lines, take your egg whites in the morning as specified above and keep in mind your protein shakes throughout the day. Take the first segment in the wake of preparing and some place between dinners the second one. That way you will achieve to keep up a steady protein stream into your muscle units.

By digging deeper into the discussion, it makes the white protein a better type of protein than any other protein. Try it as a substitute to your other protein intake for better health of you body.

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What Is Beta Alanine And How Does It Improve My Athletic Performance?
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Date: January 16, 2014 05:32 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is Beta Alanine And How Does It Improve My Athletic Performance?

beta alanineBeta alanine

Beta-alanine is classified under non-essential amino acid; which imply that the body is able to produce.

Amino Acid

Amino acids are the building components of proteins. Beta-alanine is a precursor to the compound carnosine; which, functions by regulating the acidic environment resulting from active muscles. In a case where the cellular environment inside the muscle becomes too acidic, then the muscle ceases to function. To prevent this carnosine slows down or attenuates the development of an acidic environment allowing an athlete to perform better or exercise with more work load.

What is Carnosine

Carnosine is very effective at controlling the hydrogen ions that cause then negative effects of lactic acid. Carnosine is understood to be one of the main muscle buffering substances contained in skeletal muscle. Therefore when carnosine prevents the arising of an acidic environment which characterizes a high-intensity exercise, the athlete is able to exercise at high intensities for a longer period.

When carnosine is ingested directly through the mouth it is rapidly converted into beta-alanine and histidine by the enzyme carnosinase as soon as it enters the blood stream. It is thus ineffective when carnosine is ingested directly. However,separate ingestion of beta-alanine and histidine results in these two compounds re-conversion to carnosine after absorption into the skeletal muscle.

Beta-alanine has great benefit in improving athletic performance and exercise intensity, and the building of lean muscle mass.

Research indicates that beta-alanine is the amino acid that highly affects intramuscular carnosine amount as it is the rate-regulating substrate in this chemical reaction (Dunnett and Harris 1999).

Recommended Use for Beta Alanine

It is highly recommended that beta-alanine be taken in daily dosages in order to be highly effective, with dosage amounts varying from different expert opinions as well as dependant on the athlete preference.

Studies have indicated that 28 days dosage of 4 to 6 g/day of beta-alanine supplementation resulted in an approximately 60% improvement of intramuscular rates (Harris et al. 2005; Zoeller et al. 2007)

References:

  1. //www.humankinetics.com
  2. //www.nutritionexpress.com

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Does Beta Sitosterol Help Reduce Cholesterol?
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Date: November 14, 2013 09:47 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Does Beta Sitosterol Help Reduce Cholesterol?

Beta Sitosterol plant About Beta Sitosterol

A high cholesterol level in the body is a cause to worry. Many people on learning that their cholesterol levels are way above the norm resort to healthier diets and regular exercises. While these mainstream methods of lowering cholesterol work, researchers have explored other different options that involve the use of cholesterol lowering supplements; Beta Sitosterol.

What is Beta Sitosterol

Beta Sitosterol is a plant sterol that is largely medicinal. Credible studies have shown that this compound is indeed capable of reducing cholesterol. It is able to do this by inhibiting the absorption/uptake of cholesterol from the gut. Researchers have had to perform extensive experiments to come up with these findings about the Beta Sitosterol. But how exactly does this compound achieve this?

Benefits of Beta Sitosterol

Beta Sitosterol’s chemical structure is quite similar to that of cholesterol. On ingestion and during absorption in the intestine, Beta Sitosterol will effectively compete and take the place of dietary cholesterol in the micelles thus inhibiting/lowering its absorption. Furthermore, upon absorption, Beta Sitosterol gets incorporated into the cell membrane further reducing uptake of cholesterol. This happens when Beta Sitosterol inhibits the transportation of cholesterol to the smooth endoplasmic reticulum from the outer cell membrane. This reduces Low Density Lipoproteins (LDL-bad cholesterol) and serum cholesterol levels.

Beta Sitosterol is also said to increase the receptability of the liver cells to LDL. This means that the liver cells are able to effectively absorb LDL from the blood stream reducing the level of cholesterol in the blood. Dietary cholesterol on the other hand is excreted. the use of Beta Sitosterol as a cholesterol reducing supplement has made it possible to reduce cholesterol without dieting or engaging in rigorous exercises. Users of Beta Sitosterol are however warned about prolonged use of this sterol. High concentrations in the body may have dire consequences.


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Does Ubiquinol Get Absorbed Better Than Regular CoQ10
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Date: November 06, 2013 08:52 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Does Ubiquinol Get Absorbed Better Than Regular CoQ10

 Benefits is Ubiquinol

Ubiquinol can be described as reduced form of CoQ10 (Ubiquinone). For an individual to benefit from the type of nutrient that is needed for producing cellular energy and reduce signs of aging, the body has to convert ubiquinone to ubiquinol. Studies have shown that it gets absorbed better than CoQ10. It is also known to reduce exercise induced fatigue by around 90% when compared with Ubiquinone. This is probably because CoQ10 has a chemical nature that undergoes “redox chemistry”. This implies that it flips back and forth between not having and having two additional electrons.

Importance of Ubiquinol to Human Body

This is a very important part of the human body because it transports flow of electrons that permits chemical energy to be harnessed down a gradient. This is normally the last stage where food is converted to energy to fuel the body. Ubiquinol on the other hand is the form where these extra electrons are reduced when speaking in chemistry terms. Although there is a small difference between the two, it really has big implications as this is exactly what makes it to be more absorbable in the intestines. In addition to this, the body prefers this form to perform the transport function of the blood. 

It is important to note that Ubiquinol was introduced to the market when Kaneka discovered techniques on how to stabilize the ingredient in 2006. From then, it has become an ingredient in numerous products. Various findings also show that it is the preferred form when it comes to ingestion. There are some studies that also show that this form is beneficial for patients who are suffering from advanced stage cardiac disorders. This is because it is absorbed much easily and also shows potential for greater clinical benefit. Manufactures are also looking into new and more advanced methods that will be used to make sure that it can be absorbed more easily than before.

References:

  1. //www.naturalproductsinsider.com/articles/2013/03/coq10-vs-ubiquinol.aspx
  2. //www.lef.org/magazine/mag2007/ss2007_report_coq10_01.htm
  3. //products.mercola.com/coq10-ubiquinol/

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The Amazing Health Benefits of Curcumin
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Date: April 19, 2012 07:31 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Amazing Health Benefits of Curcumin

Curcumin

Have you heard of curcumin? Curcumin is a popular spice that originated in Eastern culture. This spice is popular because it offers a lot of health benefits to people. For those individuals who are interested to achieve optimal health and want to live a longer life, it would be best to ad curcumin in their daily diets. This spice can definitely affect the overall health of individuals.

What is curcumin?

Curcumin is not just an actual spice, but it is one of the ingredients of Tumeric, which is considered a famous Indian spice. Curcumin is commonly used in making curries with a strong taste that are being appreciated in the West. However, this ingredient is consumed by many people because of the health benefits it could bring. Curcumin is very in demand in India, Middle East and Asian countries because they use curcumin as a medicine.

There are various health benefits of curcumin. If you want to take advantage of these benefits, it is important that you be aware of these health benefits:

Benefits

• Helps treat certain illnesses- According to research and studies, it has been shown that curcumin can effectively treat and prevent particular ailments such as brain problems and cancer. Individuals suffering from Alzheimer's disease can definitely overcome their condition with regular consumption of curcumin.

An effective body pain reliever- A lot of individuals, most especially the senior citizens are always experiencing body pains because of weak bones. According to a recent study, curcumin has been believed to relive pain and improve mobility for sufferers with osteoarthritis and other body pains. Curcumin contains anti-inflammatory properties that help alleviate body aches.

Positive effects on brain health- Another awesome benefit if curcumin is providing positive effects on brain health. According to reports, even just occasional ingestion of curcumin can improve brain power. It is necessary to have a healthy and powerful brain so that it is easier to think clearly all the time. It also effectively reduces the levels of toxic metals in the brain.

Helps avoid premature aging- Curcumin is packed with antioxidants, which are responsible in preventing the occurrence of premature aging. Premature aging is a very common condition, most especially to people with an unhealthy lifestyle. It would be best to stop all your filthy habits and add curcumin in your regular diet to achieve a healthy body and younger looking skin.

These are some of the amazing health benefits of curcumin. If you want to achieve a healthy body and mind, this healthy supplement is the excellent supplement to utilize. There is no recommended dose for curcumin. Studies have utilized doses between 100 mg to 8000 mg without experiencing any over dosage side effects. In fact, individuals can consume up to 12,000 mg per day.

Curamin can either be consumed as a supplement, or it can be added in certain food or meals. Basically, people in India would add this spice to their every dish so that they could attain superior health. You can also add curcumin when you are cooking, but if you have no time to cook, nutritional supplements can be the perfect alternative.

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Can tea Tree Oil Kill Bugs?
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Date: September 26, 2011 11:26 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can tea Tree Oil Kill Bugs?

Tea tree oil is known as an essential oil which is light yellow in color with a camphoraceous scent. It is extracted from the leaves of Melaleuca alternifolia which originates from the northeast coast of Australia. The other name of tea tree oil is melaleuca oil.

Tea tree oil has been studied on its medicinal benefits. Such studies revealed that tea tree oil has a potent anti-viral, anti-bacterial, and anti-fungal properties. In fact, since the olden times, tea tree oil can administered topically as an antiseptic agent. In addition, tea tree oil is also popularly used as one of the ingredients among many cosmetic products. Industrially, tea tree oil has been controversial whether it can be used to kill bugs or not.

Experiments on "concentrated" tea tree oil and bed bugs have shown that it can effectively kill bugs and other insects. However, it cannot be used at home because concentrated forms of tea tree oil have been found to be toxic to the human body. The commercial preparation of tea tree oil is diluted so that it cannot cause harmful effects to the body. Diluted tea tree oil, on the other hand, cannot kill bugs and insects. Health experts also further stipulated that it is significantly dangerous to use “concentrated” tea tree oil at home specifically at your bedroom. If tea tree oil in undiluted form is introduced inside the body either by ingestion or inhalation, it can have a negative effect on the liver so it is wise to always dilute this oil before ingesting.

If the room is exposed to “concentrated” tea tree oil, make sure to open the windows and provide adequate ventilation. Avoid entering the room for a short span of time because it the air is toxic. Eventually, if “concentrated” tea tree oil is smeared on the skin, it may cause inflammation as manifested by swelling and redness, blistering and itching. If swallowed, concentrated tea tree oil can cause significant diarrhea.

If diluted tea tree oil is employed for bed bugs, it can only make the bugs weak, not killed. The diluted form of tea tree oil is non – toxic to humans and is considered to be a cheaper remedy for the control of bed bug bites. Therefore, it can kill bugs but in concentrated form. However, concentrated tea tree oil must not be used as a household insect killer because of its toxicity. On the other hand, diluted form of tea tree oil is non – toxic but in cannot kill bugs and insects.

As mentioned earlier, tea tree oil is used as an ingredient of many cosmetic products such as facial creams, ointments, lotions, soaps, shampoos and even acne removing agents. Allergic reaction to tea tree oil is rare. However, if hypersensitivity occurs, manifestations include mild dermatitis, blister formation and rashes. It is important to remember that tea tree oil is for external use only. It must not be introduced inside the body even in very small amount because it can cause mild to severe adverse reactions. If untoward effects occur after use, consult your doctor.

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What is Bioperine and How Does It Help with Absorption of Vitamins
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Date: April 21, 2011 03:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is Bioperine and How Does It Help with Absorption of Vitamins

Get more from your food with Bioperine.

Bioperine is a patented form of an alkaloid found in black pepper. It is derived entirely from piperine, an organic compound responsible for the spicy taste of black pepper and long pepper. Piperine has been noted for its thermogenic properties believed to speed up the absorption metabolism of digested foods. Recent studies have discovered that it also interferes with the release of enzymes that govern the bioavailability of drugs and supplements. By so doing, it enhances the rate of absorption of vitamins.

The human body has a complex mechanism of controlling the substances that get in and out of systemic circulation. The first pass occurs in the alimentary canal, where gastrointestinal enzymes break down substances into smaller compounds. It is believed that a very small percentage manages to undergo intestinal absorption after digestion. In general, this is the part where constituents of supplements remain undigested and instead enter the colon together with waste materials.

The liver plays a central role to the metabolism of drugs and most bioactive compounds. The compounds that pass the intestinal walls and enter the hepatic portal system, a group of veins that direct blood and other compounds from the gastrointestinal tract to the liver, is further metabolized inside the liver. Anything that the body considers foreign is sent to the kidneys and easily excreted through the urine. This is the reason why bioavailability is significantly reduced after ingestion.

Counteracts Effects of Enzymes

Bioperine is the only compound known to interact with enzymes that controls the metabolism of foreign materials within the intestinal epithelium. P-glycoprotein is released in the digestive tract to deal with drugs and xenobiotics found in our diet. Vitamins are no exception to the tightly regulated process of absorption in the intestines. These enzymes transport digested compounds to the liver.

It has been observed that piperine appears to reduce the expression of p-glycoprotein in the alimentary canal and other parts of the body. Proponents believe that bioperine, a purer form of piperine, is capable of counteracting the effects of the enzyme within the intestinal epithelium, making it easier for vitamins and supplements to enter the hepatic portal system.

Increases the Rate of Metabolism

Not all compounds that undergo the first-pass effect interact with the cells and tissues they are supposed to act on. If they should have an effect on any cell, they are still subjected to the actions of enzymes specialized for the expulsion of xenobiotics found in the systemic circulation and the rest of the body. For example, CYP3A4 removes foreign materials from the cells and facilitates their excretion.

Bioperine is touted to induce thermogenesis and stimulate cellular activities. By so doing, the effects of bioactive compounds are achieved while they remain inside the cells and tissues. The thermogenic properties of bioperine influence the rate of metabolism of digested compounds, including vitamins, minerals, and components of herbal preparations. Note that it can increase the update or prescription medications as well, so caution should be observed when consuming bioperine with medications.

If you want to give your body a nutrient boost, add bioperine to your supplement regiment to boost absorption.

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How Does the Herb Holy Basil Help with My Health?
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Date: March 10, 2011 02:04 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does the Herb Holy Basil Help with My Health?

Holy Basil And Cholesterol, Inflammation, and more

Ocimum tenuiflorum, known as Holy Basil in the vernacular, is an herbal plant indigenous to South Asia, where it is called Tulsi. It is widely distributed across the subcontinent of India and surrounding countries and is primarily cultivated for its age-old medicinal benefits in addition to its religious significance to Vaishnavite practices of Hinduism. It has earned popularity as a health tonic over the centuries, and recent studies have supported its positive effects on human health. Today it is often associated with lowering cholesterol and glucose, acting as an antioxidant, and regulating inflammatory intermediaries.holy basil plant

Counteracts Stress Factors

The juice of holy basil has long been reputed to display adaptogenic properties. There have been countless accounts of its effectiveness in combating stress. In fact, the most compelling of all anecdotal evidence has something to do with its ability to create a feeling of wellness right after ingestion, the same tonic benefits attributed to ginseng. To date studies point to its homeostatic effects on the stress hormone cortisol, creating homeostatic effects on its metabolites and their interactions with compounds released in response to stress.

Neutralizes Free Radicals

Holy basil has been observed to show antioxidant activities, and this is one of its mechanisms in allaying symptoms brought on by fatigue. Free radicals are released by the body to dispose of pathogens, but are in turn disposed of by endogenous antioxidants. Oxidative stress ensues when there is an imbalance between the production of free radicals and the ability of the body to neutralize them. The polyphenols found in holy basil helps the body quench excesses of free radicals.

Lowers Bad Cholesterol

There has been a growing body of literature devoted to the lipid-lowering properties of holy basil. The phytochemicals found in holy basil have been cited to affect the metabolic pathway that produces very-low-density lipoproteins, which is a precursor to low-density lipoproteins, or bad cholesterol, and bring about an increase in high-density lipoproteins, dubbed good cholesterol. Also, it has been associated to the overall decrease of lipids present in the bloodstream, notably free fatty acids.

Reduces Blood Glucose

One of the earliest observations on the health effects of holy basil is its properties that counter the progression of diabetes. It has been reported many times to have helped patients of type 2 diabetes mellitus, which results from the compromised ability of cells to respond to the hormone insulin. The use of holy basil extracts has yielded promising results on promoting the glucose uptake of cells, and, of course, the consequent decrease in glucose present in the blood.

Influences Inflammation

Holy basil has been extensively studied for its anti-inflammatory benefits. The most recent research has pointed out that organic compounds found in holy basil may inhibit the enzyme called COX-2, which facilitates the synthesis of inflammatory mediators. Eicosanoids are endogenous substances produced by local tissues during inflammation, and a special group called prostanoids is responsible for the pain tied to inflammation. By targeting COX-2, holy basil greatly aids against inflammatory diseases such as arthritis.

What is stopping you from giving holy basil a try today?

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Fight Free Radical Damage From Toxins With Vitamins And Herbs
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Date: July 28, 2010 11:34 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fight Free Radical Damage From Toxins With Vitamins And Herbs

There are many things that destroy the immune system. Each day we are bombarded with them in many forms. The following are some of the most common ones that are encountered.

Agene, also known as Nitrogen Trichloride, is used to bleach flour and give it a white appearance. Unfortunately, it can cause epileptic-like fits along with failure of muscle coordination. Excessive use of alcohol also severely impairs the immune system. It increases susceptibility to infection and weakens the central nervous system. Alcohol promotes chronic lung disease, malignancies of the neck and head, intestinal problems, hypoglycemia, diabetes, liver disease, and a whole variety of other problems. B vitamins, folic acid, niacin, vitamin E, magnesium, zinc, and protein are depleted by alcohol. All of these nutrients play a huge role in immune health. Aspartame breaks down in the digestive tract into a toxic material known as methanol. In order to prevent methanol from metabolizing into formaldehyde, a poison, a person needs to take another poison, ethanol.

Glutamic acid is a substance that is found in monosodium glutamate, a flavor enhancer. It affects the central nervous system and can trigger depression, gloomy fantasies, and rage for as long as two weeks following the ingestion of monosodium glutamate. High-diet fat intake increases the levels of bile acids in the colon. This breaks down into deoxycholic and lithocholic acids, both of which are cancer-causing elements. This can cause cancer of both the colon and the rectum. A diet that is high in animal protein and fat can cause cancer of the pancreas, breast, gallbladder, ovaries, uterus, prostate, and leukemia. Junk food such as sweets, white flour, and white sugar products, put a double amount of stress on the body. When too much junk food is eaten, the appetite for good, wholesome food is dulled.

Caffeine decreases immunity in the body, with fibrocystic breast disease being connected with the consumption of foods that contain caffeine. It is often caused by the chemicals methylxanthine, theophylline, and theobromine, which are found in coffee, black tea, cola drinks, chocolate, and other soft drinks. These elements act on hormones that cause breast tissue to develop fibrocystic lumps. Caffeine takes away the body’s own use of iron and inositol, and is often suspected of causing cancer in the pancreas.

Food dyes and flavorings are the culprits in behavioral problems that occur in children and adults, with some of these problems being learning disabilities and hyperactivity. Sodium nitrate is a preservative that is often found in cured meats like hot dogs, bologna, and ham. It has the potential to produce permanent epileptic changes in brain activity and damage the central nervous system.

High protein diets can deplete calcium in the body, especially when the source of protein is an animal product. There are concentrated doses of hormones and antibiotics that are found in beef which suppress the immune system and promote tumor growth. Poly-unsaturated fats undergo a process that produces rancidity in oils. This process releases dangerous free radicals, which eventually lead to cancer.

Heavy metals like lead and mercury can cause serious damage to the nervous system, with even small amounts being considered toxic. Lastly, the wide use of vaccinations and antibiotics is considered to be one of the main causes of immune system disorders.

Our bodies are under constant attack by our toxic environment. Fortunately, with regular vitamin and herb use, one can help the body restore its immune system to proper function so we can live a happier healthier life.

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Vitamin A Vs Beta-Carotene and its Safety
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Date: May 09, 2010 08:20 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamin A Vs Beta-Carotene and its Safety

Although Vitamin A deficiency is prevalent throughout the world, retinol toxicity is a common occurrence as well. About five percent of those who supplement with vitamin A unknowingly suffer from toxicity symptoms. It should be noted that supplementation at 5,000 to 10,000 IU per day of preformed vitamin A, which is dose that is well within the range that is offered in many popular vitamin supplements is a safe effective doses, additional supplementation of vitamin A may actually lead to a cumulative toxic overdose. Additionally, accidental ingestion of one single, large dose of vitamin A, can produce acute toxicity in children, always keep vitamin A out of reach of small ones.

A large study on over 22,000 pregnant women who supplemented with vitamin A during early pregnancy found that those women taking more than 60,000 IU of preformed vitamin A per day in the form of supplements had about one in fifty-seven of a chance of a malformation attributable to the supplement. In consuming more than 60,000 IU of vitamin A, a five-fold greater risk for birth defects arises as compared to consumption of less than 25,000 IU per day. The prevalence of birth defects seems to be greatest in those women who consume high levels of pre-formed vitamin within the first seven weeks of their pregnancy. Authors of the study concluded that women who may possibly become pregnant should limit their retinol intake to below 15,000 IU, or supplement with beta-carotene instead.

Beta-carotene is the orange/yellow-colored pigment that is often found in many garden vegetables. It is a retinal precursor. The body is able to easily convert beta-carotene into vitamin A by turning the carotene molecule into two molecules of retinol as they are needed. This allows for the avoidance of toxic accumulation of pre-formed vitamin A. Once beta-carotene is transformed into active retinol, it offers the same beneficial affects. The only symptoms associated with beta-carotene supplementation are loose stools or slight discoloration of the skin. This makes beta-carotene, even at high doses, safe for the body because it does not exhibit toxicity. An added benefit of beta-carotene is that it is a much more potent antioxidant than retinol, as it provides even greater protection against oxidative challenges. The worst thing that can happen to you if you take too much beta-carotene is that you may turn orange like a carrot. However, this should not be a worry because you will be just fine.

The majority of nutrients that are used in supplementation have a large measure of safety. Unfortunately, the use of vitamin A warrants prudence and caution. This is especially crucial when it is consumed by children or those women who are pregnant. Because of this, the level of vitamin A in excess of the upper limit of intake that is prescribed by the Food and Nutrition Board of the Institute of Medicine, is a crucial criterion in determining how good a product is. The criterion for potential toxicities asks whether the nutritional supplement contains vitamin A. If so, it asks whether the potency of vitamin A exceeds 100% of the upper limit of intake that is prescribed by the US Food and Nutrition Board.

To be on the safe side, take beta-carotene which has no side effects even at very high doses but exhibits the same health benefits of consuming preformed vitamin A. Look to your local or internet vitamin store for name brands like Solaray and Source Naturals for all your Vitamin A and beta-carotene needs.

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Milk Thistle And Silymarin
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Date: August 12, 2009 12:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Milk Thistle And Silymarin

In Europe, milk thistle was used as a well-known remedy for liver problems and also as a digestive aid. Pliny the Elder, the early Roman writer, explained how the juice of milk thistle mixed with honey was used for carrying off bile. Gerard, an herbalist, said in 1597 that milk thistle was one of the best remedies for liver-related diseases. Milk thistle was also given to nursing mothers to improve milk production.

The liver is an extremely important organ that is found in the body. It is responsible for filtering toxic material from the body, which prevents accumulation that can lead to disease and death. Often, the vital functions of the liver are overlooked. Nevertheless, they are extremely important. It is essential to keep the liver working properly. Milk thistle has been proven to be very beneficial for liver function. Milk thistle extract has been shown in observations to help reverse both acute and chronic liver problems, including cirrhosis and viral hepatitis. The antioxidant properties may be due to the bioflavonoid content. Milk thistle has also been found to help heal the liver from damage that occurs from alcohol toxicity. It has been used to treat many different liver ailments. Among these are fatty liver disorders, chronic hepatitis, inflammation of the bile duct, hardening of the liver, and cirrhosis. Milk thistle is also thought to actually help liver regeneration when part of the liver is removed.

Milk thistle possesses a variety of compounds which are known as Silymarin. This includes silybin, silydianin, and silychristin. All of these substances are known to protect the liver against some toxins, which helps to increase the function of this important organ. Silybin is used as an antidote to the deathcape mushroom, which is known to destroy liver cells. The deathcap species is one of the most toxic of liver poisons and has a death rate of up to fifty percent. A study with sixty patients suffering from deathcap poisoning treated with silybin produced incredible results. None of the participants died. Silymarin is an effective remedy if it is administered within forty-eight hours of ingestion. This compound seems to occupy the receptor sites to protect the cell membranes. Not only does it work to treat serious liver conditions, but it also prevents damage from occurring. Silymarin contains amines which are known to help stimulate the production and flow of bile. This compound has been found in studies to work exclusively on the kidneys and liver. Milk thistle has also been shown to stimulate the synthesis of protein.

The seeds of the milk thistle plant are used to provide alterative, antioxidant, galactagogue, hepatic, and stimulant properties. The primary nutrients found in this herb are bioflavonoids. Primarily, milk thistle is extremely beneficial in treating cirrhosis, hepatitis, jaundice, kidney problems, and liver disorders. Additionally, this herb is very helpful in dealing with alcoholism, appetite loss, high blood pressure, boils, chemotherapy, depression, epilepsy, fatty deposits, gas, heartburn, heart problems, hemorrhages, hypoglycemia, indigestion, absent lactation, menstrual symptoms, effects of radiation, skin diseases, varicose veins, and the effects of toxins.

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Polyphenols is an Antioxidant
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Date: October 13, 2008 02:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Polyphenols is an Antioxidant

A lot of new evidence suggests that consuming more plant polyphenols is a powerful way to protect aging arteries. These polyphenol compounds help improve endothelial function, a critical factor in preventing atherosclerosis; inhibit abnormal platelet aggregation which causes most sudden heart attacks and strokes; fight inflammation; and support healthy blood lipids. Polyphenols that are of particular interest are those derived from green tea, cocoa, apples, and black chokeberry, which all complement each other in helping to build the body’s defenses against various ailments.

All throughout history, the medicinal potential of plants has been celebrated. Modern science has found that edible plants are to be valued for their high vitamin and fiber along with their rich store of polyphenols. Polyphenols are found in fruits and vegetables, as well as cocoa, tea, and chokeberry and have been shown to be a type of chemical that may protect the body against some common health problems as well as certain effects of aging. Polyphenols protect cells and body chemicals against damage that is caused by free radicals and block the action of enzymes that cancers need for growth, deactivating substances that promote the growth of cancer. The increased consumption of polyphenols has been associated with a reduced risk of cardiovascular disease and potentially cancer and stroke.

In Aztec culture, cocoa was one of the most highly prized due to its medicinal and stimulant value, along with its taste. The polyphenols found in cocoa occur in a higher concentration than can be found in any other food. They also have antioxidant activity much greater than those found in broccoli or red wine. The catechins and procyanidins that are found in cocoa seem to lower the risk of cancer and heart disease. Cocoa has also been proven in studies to reduce blood pressure, improve insulin sensitivity, and slightly ameliorate the lipid profile. Although cocoa is a healthy and tasteful food, it is high in caloric content and therefore, its ingestion must be accompanied by the careful reduction of calories from other sources.

Many studies have shown that tea polyphenols can be extremely beneficial to human health, possessing anti-obesity, antihypertensive, anti-diabetic, antioxidant, anti-inflammatory, and anticancer effects. Tea is the world’s second most consumed beverage, although less popular in the Western diet. Green tea and white tea retain more polyphenols in their intact form, as oolong and black teas undergo more extensive processing before they are marketed. Tea polyphenols break down in high temperatures therefore; freshly brewed tea contains a higher amount of polyphenols per serving than do tea drinks that are canned or bottled.

Similar to the blueberry, the black chokeberry is high in anthocyanins and antioxidant activity. It is native to eastern North America and has become popular in Eastern Europe and Russia due to its health-promoting potential. This berry protects the liver from chemical poisoning and the stomach lining from ulcers. It also acts as an anti-inflammatory, lowers harmful cholesterol levels, and prevents dangerous swings in blood pressure. Some studies have shown that this berry seems to prevent the harmful mutations in cell cultures, regulates immune function of human white blood cell cultures, and suppressed the growth of human colon cancers.

--
Buy Polyphenol supplements at Vitanet ®, LLC

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DHEA
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Date: August 15, 2008 11:53 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: DHEA

In the recent past, DHEA has shown scientists its amazing abilities within the human body. Clinical tests have created a huge amount of interest for both scientists and consumers, with estimates of about 500 in-depth clinical studies on DHEA taking place. These tests, which have been conducted at some of the most prestigious medical research centers and universities in the country, have proven DHEA to be one of the most important anti-aging and anti-disease substances of the 21st century.

DHEA is a crucial and important hormone that is produced in the adrenal glands. It is often called the mother hormone, as it forms the base for the biochemical actions of hormones like testosterone, estrogen, progesterone, and corticosterone. These hormones control important body functions that determine metabolism, energy output, endocrine mechanisms, and reproductive capabilities. DHEA directs the entire endocrine systems through activating and inhibiting enzymes. In its many clinical studies, DHEA has shown an unusually wide variety of physiological benefits. Although it has been known for many years that DHEA is made by the adrenal glands, the function of DHEA in the body has only been recently studied.

DHEA is produced by the adrenal glands, but it can also be found in non-patented prescription drugs and other over-the-counter forms. A lot of these supplements contain a synthetic DHEA-S. A lot of people consider Dioscorea extract, which can be found in Mexican Wild Yam, to have a natural source of DHEA. There are a lot of naturally occurring compounds that can mimic the actions of DHEA and, at the time, do not require a prescription. Wild Yam and Mexican Yam can give a botanical precursor of DHEA, which is considered a substantial source by a lot of health advocates. A great number of studies on DHEA that is derived from Mexican Yam have been conducted, with results concluding that DHEA derived from Mexican Yam and Dioscorea extract is a great idea. However, some controversy surrounds the value of Wild Yam as a valuable source of DHEA.

DHEA is used in the body to make other hormone, as it is the most dominant of all the hormones present in the body. It contributes to the proper growth of brain cells, inhibits the conversion of carbohydrates to fats, decreases the formation of blood clots, regulates hormones, decreases the stickiness of platelets that can clump to cause heart attacks and strokes, increase estrogen in women and testosterone in men, lowers LDL cholesterol, enhances overall immunity, and decreases symptoms of an enlarged prostate.

DHEA helps to reduce menopausal symptoms, promotes thermo genesis, helps to increase muscle mass, stabilizes blood sugar, inhibits appetite and discourages eating, boosts endurance, inhibits diseases associated with aging, helps to restore collagen and skin integrity, fights fatigue and depression, helps to inhibit certain tumors, improves calcium absorption to discourage osteoporosis, acts as an anti-inflammatory, and helps to lower blood pressure.

DHEA levels dramatically vary in each individual and can drop as a result of stress or other conditions such as blood sugar, fever, hypertension, nicotine ingestion, alcohol consumption, drinking coffee, and the presence of various diseases. Taking birth control pills and other synthetic hormones can also deplete levels of DHEA. When any of these occur, supplementation is needed. Therapeutic doses range from 5 to 25 milligrams per day which can be found here at VitaNet, LLC.

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Apple Cider Vinegar
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Date: August 13, 2008 03:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Apple Cider Vinegar

Apple cider vinegar is an old folk remedy claimed to be beneficial in treating a long list of ailments. It is sold today by "health food" companies and others who claim it has remedial properties. Apple cider vinegar is a type of vinegar made by the fermentation of apple cider. Unlike white vinegar, apple cider vinegar is a light yellow-brown color and is often sold unfiltered and unpasteurized with a dark, cloudy sediment called mother of vinegar (consisting mainly of acetic acid bacteria) settled at the bottom of the bottle.

Over the centuries, vinegar has been used for countless purposes: making pickles, killing weeds, cleaning coffee makers, polishing armor, and dressing salads. While many of the folk medicine uses of vinegar are unproven (or were disproved), there is some medical research backing them up.

The main ingredient of apple cider vinegar, or any vinegar, is acetic acid. Apple cider vinegar is also said to contain an abundance of complex carbohydrates and dietary fiber. Do not use a metal container when making vinegar or storing it; acid in the mixture will corrode metal or aluminum objects making the solution unfit for consumption.

When it comes to losing weight, experts say you are what you drink. Apple cider vinegar has recently found new use as a weight loss and weight management aide, and has been included in many over the counter weight loss nutritional supplements. Anecdotally, ancient Egyptians used apple cider vinegar for weight loss. The acetic acid in this vinegar can curve the appetite which benefits those trying to loose weight and keep it off.

Some say apple cider vinegar can help arthritis, osteoporosis, high blood pressure, and assist in digestion. It is also thought to help the body maintain a healthy alkaline level. The acidic nature of this vinegar has been said to help scalp problems such as dandruff, itchy scalp, baldness and thinning hair. Apple cider vinegar can also help gastric problems as well.

Civil War, soldiers used vinegar to prevent gastric upset and as a treatment for various ailments including pneumonia and scurvy. Research suggests that this vinegar can delay gastric emptying. Ten patients with type 1 diabetes mellitus and diabetic gastro paresis were studied; when the study was over the patients were able to demonstrate a significant delay in already delayed gastric emptying after the ingestion of vinegar. So delaying the rate at which the stomach empties can keep a sense of fullness for those looking to loose weight.

The effect of vinegar on blood glucose levels is perhaps the best researched and the most promising of apple cider vinegar's possible health benefits. Several studies have found that vinegar may help lower glucose levels. For example, a small study compared the effect of vinegar with white bread on blood glucose and insulin levels. Keeping blood sugar lower is important to diabetic patients which can help reduce the use of insulin. Subjects with type 2 diabetes showed a slight improvement in insulin sensitivity, but postprandial blood glucose and insulin levels were not affected when apple cider vinegar was added to a meal.

In conclusion, apple cider vinegar could theoretically interact with diuretics, laxatives, and medicines for diabetes and heart disease so you must be careful. Apple cider vinegar should always be diluted with water or juice before swallowed. If you have diabetes, check with your doctor before using apple cider vinegar. Furthermore, blood glucose must be monitored more frequently in patients with diabetes treated with insulin experiencing gastro paresis to prevent adverse hypoglycemic episodes. All those taking medications should consult a doctor because the acid in this vinegar can enhance absorption and increase Side effects.

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Can the Fatty Acid CLA Help me Lose Weight ?
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Date: July 14, 2008 03:28 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can the Fatty Acid CLA Help me Lose Weight ?

CLA is conjugated linoleic acid, a compound known as a trans fatty acid due to its stereochemistry, and while trans fatty acids are generally regarded as harmful, CLA is not because it is conjugated. This means that it has alternate single and double bonds in the backbone carbon chain, and the overall energy of the molecule is therefore reduced.

Linoleic acid itself is one of the omega-6 fatty acids, the 6 referring to the double bond at the sixth carbon from the omega and of the carbon backbone chain. It is believed to be the cause of heart disease and obesity due to its increasing use in the diet at the expense of omega-3 fatty acids. When the molecule is conjugated, however, the fatty acid has different chemical properties to the standard isomer, and natural CLA is mainly found in cattle products, such as beef and dairy products.

Conjugated linoleic acid is present in cattle because it is formed when linoleic acid is converted to oleic acid by rumen bacteria, that are responsible for the microbial fermentation of the feed of ruminant animals such as sheep and cattle. When oleic acid is formed, so too is CLA. However, the form used in supplements is manufactured from vegetable oils, and therefore suitable for use by vegetarians. The usual vegetable oils used are safflower oil and sunflower oil.

It is believed to possess several beneficial properties, including antioxidant and anti-cancer properties, but it is for its ability to reduce body fat that it is best known to most people. A growing amount of information is being collected on the use of CLA as a supplement in the weight loss industry, although there are as yet no definitive mechanisms that explain its action. However, recent studies have indicated it possess properties that can help to reduce the levels of low density lipoproteins in the blood, and reduce the possibility of atherosclerosis due to LDL oxidation by free radicals.

It is also theorized that CLA in some way regulates the prostaglandin biosynthesis that controls the level of hormones in the body that can regulate growth. An increase in growth hormones is one way in which athletes promote an increase in muscle bulk, while reducing their fatty tissue mass. CLA is also purported to increase thermogenesis, and so promote the loss of body fat and overall weight.

Although most studies on the effect of conjugated linoleic acid in reducing body weight have been carried out on animals, recent animal studies have indicated that might not so much reduce weight, as to increase muscle bulk while reducing that of body fat. The end result, therefore, is not a loss of weight, but a leaner body that has more muscle and less fat. All it needs is the results on animals to be transferred to humans, and this, of course, is frequently the case. However, initial studies on the use of CLA in the human diet have been very positive, so the signs are good.

Most scientific progress in human biochemistry has been obtained by virtue of prior studies on animals. These studies, of course, have been beneficial to the animals, making them leaner and much fitter than they otherwise would have been. It is believed that the same will be true of humans taking CLA as a supplement. In fact, recent studies are split about 50/50 with regard to the effects on humans.

While some studies have shown no benefit, about an equal number have shown a positive benefit in the reduction in the mass of fat in the body. Some of the negative studies may have been flawed in measuring total body weight, and not the relative amounts of muscle and fat, and also basing their results on people already with a low level of fat in their body. In that respect, then, the results look very favorable, and taking CLA as a supplement is likely to help you to reduce fat and increase muscle, if not altogether lose total body weight. However, is that not the end result that most people want? They might not want to be lighter in weight, just to have more muscle mass and less fat tissue.

In a study shown at a 2002 Experimental Biology meeting, it was shown that is was possible to substantially reduce body fat mass by taking CLA alone, and when it was taken in association with guarana, both the size and the number of fats cells in the body were reduced by 50%. However it has also been shown that CLA can be oxidized by free radicals shortly after ingestion, and that sesame lignans help to prevent this. Since sesame lignans can also be used in conjunction with CLA to reduce fat by increasing the level of fatty acid oxidation in the liver, than the benefit of CLA seems obvious.

The antioxidant effect of CLA is one possible explanation for its anti-cancer properties, though there are others. Its antioxidant properties also have an anti-catabolic effect, in that it can help to prevent the wastage of muscle tissue. The FDA has published studies that attest to these anti-cancer properties. Diabetics, however, should consult with their physician before taking CLA as a supplement, since there is a body of thought that it reduces sensitivity to insulin. Others believe the opposite, so more studies might be needed in this aspect of the substance before it can be said to be safe for use by diabetics.

Over recent years, the American diet has increased significantly in its content of the undesirable linoleic acid, due to its ubiquitous presence in margarines, and has reduced in CLA due to modern farming methods. Cattle feeding techniques have resulting in a reduction of CLA in meat products and milk, although eggs are still a rich source, and the CLA in eggs can resist temperatures used in normal cooking methods such as frying, boiling, etc.

It is this CLA deficiency in the diet that has been proposed as one of the reasons for the current obesity problem in the USA. The European diet contains more beneficial fatty acids in general than the American diet.

However, there is an increasing body of evidence being accumulated that collectively that suggests almost unequivocally that CLA can help you lose body fat. Unless you are diabetic, there are few if any contra-indications and an increasing number of people are finding it effective not only to lose body fat, but to replace it with hard lean muscle.

--
loss weight at Vitanet ®, LLC

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Multiple Vitamins
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Date: June 11, 2008 04:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Multiple Vitamins

Multiple vitamins should be designed with one purpose in mind. They should provide you the ability to properly balance your regular diet with the additional vitamins, minerals, amino acids and antioxidants needed to make your diet nutritionally complete.

It is rare that people follow the recommended daily allowances in their regular diets. For this reason, multi-vitamins were developed to provide the missing nutrients to your daily diet. Vitamins designed with this purpose will automatically provide you with the essential additional nutrition you need to boost your health and wellness.

The Correct Multi-vitamin Make-Up:

A good multivitamin supplement will contain all of the following ingredients. It is designed to balance an average diet and boost health and wellness.

* Major vitamins * Minerals * Amino acids * Carotenoids * Tocopherols * Tocotrienols * Antioxidants

Antioxidants are an important part of any diet because they attack and neutralize free radicals. These fragments of chemicals are caused by:

* Normal metabolism * Pollution * Ultraviolet radiation * Rancid oil * Other toxins

Scientists believe that free radicals are one of the elements responsible for aging and degenerative diseases like Alzheimer's, arthritis and cancer. It is because of the nutrient deficiencies in our regular diets that we have become more susceptible to degenerative diseases.

Mixed Tocopherols and Tocotrienols:

Vitamin E is a series of related compounds. The four main forms are alpha, beta, delta and gamma. Most multi-vitamin supplements only contain large amounts of alpha tocopherol. A healthy diet needs a mixture of them all.

When too much alpha tocopherol is induced, gamma tocopherol is depleted. This causes deficiencies because gamma tocopherol is crucial to good health as well. For this reason, it is important that your tocopherol intake is balanced. A mixed intake of all tocopherols is more effective in preventing cardiovascular disease.

Tocotrienols are potent antioxidants that complement the alpha tocopherol. The combined nutrients are much more effective at preventing oxidation. This is why you must have a balanced combination of tocopherols and tocotrienols to maintain a healthy diet and a healthy body. To accomplish this you must have a balance of all of the compounds that make up vitamin E.

Mixed Carotenoids:

These are the red, orange and yellow plant pigments that are found in all of our fruits and vegetables. All of these contain different amounts of carotenoids, but the colors are often hidden by the plant's chlorophyll content. Examples of foods containing large amounts of carotenoids include:

* Kale * Collard greens * Swiss chard * Broccoli

Tomatoes contain Lycopene, which is a red carotenoid found in tomatoes. It is a potent antioxidant that reduces the risk of prostate cancer. Unfortunately, carotenoids are better absorbed through the ingestion of supplements than from foods. Multi-vitamins usually only contain beta carotene. It is important to find one that contains beta carotene, alpha carotene, lycopene, lutein and zeaxanthin.

The Bottom Line:

A complete multiple vitamin supplement is necessary as a part of a daily health and wellness regimen. The best multi-vitamin contains a healthy balance of everything listed above in the correct dosages. It is important to do your homework and be sure the multi-vitamin you choose will do its job correctly.

Learn as much as you can about your own body's individual nutritional needs. By giving your body proper nutrition, you help it to fight off illness and diseases much more efficiently. A complete multi-vitamin will:

* Strengthen your immune system * Decrease your risk of cancer, heart disease and osteoporosis * Increase your level of energy * Elevate your moods * Help you to enjoy a healthier, more productive life

Choose a multi-vitamin that has been developed based on the latest science and technology. You will be taking a well-rounded supplement that was designed to properly complement a typical daily diet.



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Antioxidants For The Body
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Date: June 10, 2008 11:27 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Antioxidants For The Body

Eating the fruits and vegetables that naturally contain antioxidants is the best way to get them into your system. Mixing them into a well-balanced and healthy diet is the best method of all. This way you reap the benefits of all of the antioxidants in a natural combination.

The benefit of dietary antioxidants is that they slow the chemical process of oxidation. This oxidation is what causes narrowing of the arteries and heart-related health problems due to cholesterol deposits. Eating a regular variety of herbs, vegetables and fruits that contain antioxidants is the best way to maintain good health. Some foods that contain antioxidants include:

* Tomatoes
* Garlic
* Onions
* Rosemary
* Grapes
* Pomegranates

Antioxidant supplements are available, lab testing have shown that they are just as effective as their natural counterparts. Natural foods contain ranges of antioxidants that work together synergistically. These combinations of antioxidants are much more effective.

More Benefits:

Antioxidants and other nutrients are needed by the body to protect against cell damage. They also may reduce the risks of certain forms of cancer.

It has been discovered that the mitochondria (cell power plants) are a major source of oxidant production. They are also a target for the damaging effects of the very oxidants that they produce. This is a major cause in the advancement of cellular aging, called apoptosis.

It is believed that in apoptosis, each cell has a fixed number of cell divisions that it is capable of. After the cell has used its allotted number of divisions, it ceases to function. Oxidative damage is also a contributing factor of DNA mutation, which causes further malfunction of the cells.

Most Common Antioxidants:

The following is a list of the most common antioxidants, what benefits they offer and where to find them:

*Beta-carotene keeps the skin healthy and promotes growth and development of bones. It also helps to prevent night blindness and fight infection. Beta-carotene is found in vegetables and fruits: carrots, cantaloupe, apricots, broccoli, peppers, tomatoes, spinach, sweet potatoes and pumpkin.

* Vitamin C destroys free radicals inside and outside cells. It helps in the healing of wounds, preventing bruising, formation of connective tissue, iron absorption and keeping gums healthy. Vitamin C is being studied for its beneficial effects in reducing cataracts, cancer and heart disease. Foods high in vitamin C include tomatoes, citrus fruits and juices, berries, mango, papaya, peppers, cabbage, spinach, broccoli and potatoes.

* Vitamin E acts as the essential fat protector in cell membranes and red blood cells. It reduces the risk of heart disease, cancer and other diseases associated with age. Vitamin E is found in peanut butter, nuts, seeds, vegetable oils, margarine, whole grains, wheat germ, salad dressings and avocado.

* Selenium helps the body maintain healthy hair and nails. It also enhances immunity and, along with Vitamin E, prevents cell damage. Vitamin E reduces the risk of cancers, especially prostate, lung and colorectal. The best sources of Selenium include brazil nuts, garlic, meat, eggs, poultry, seeds, seafood and whole grains. The amount of selenium found in plants depends on the soil content in which they are grown.

Antioxidants benefit the body by providing a layer of protection for the tissues and cells. They are the front line of the body's protection against free radicals. Free radicals are unstable by-products of oxygen that cause premature aging and degenerative diseases. They also come from environmental sources, such as pollution, UV rays and other toxins. Foods rich in antioxidants help to clean free radicals from the body. They also help to prevent various age-related diseases, cancers and heart disease.

Maintaining a healthy, nutritionally balanced body that has the ability to fight disease and infection is a prime way to live a long, disease free and happy life. Regular ingestion of antioxidant rich foods or supplements is the best method to achieve this.

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Cranactin - Cranberry Extract
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Date: May 21, 2008 10:24 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Cranactin - Cranberry Extract

Cranberry is a fruit native to North America. It typically grows in bogs, and commercial production is mainly performed in Massachusetts and Wisconsin.

For ages, cranberry has been used for the prevention and treatment of urinary tract infections. Research suggests that it prevents bacteria from adhering to host cell surface membranes. It was used by Native Americans to treat ailments of the bladder and kidneys. The cranberry was documented in the 17th century as a treatment for several ailments, including:

* Blood disorders * Liver problems, vomiting and stomach ailments * Loss of appetite * Scurvy *Cancer

Cranberry was used as an effective treatment for urinary tract infections long before antibiotics were invented. It is still recommended by physicians to be used in conjunction with a prescribed round of antibiotics for treating bladder infections.

Important Facts

Statistically, one in every five women in the United States suffers from bladder infections in her lifetime. Three percent of these women suffer from recurrent urinary tract infections (UTIs). Approximately 11 million women each year receive medications to treat UTIs. Studies show that women with a history of bladder infections can reduce the frequency of those infections by regularly drinking cranberry juice.

There have been no significant reactions discovered between cranberry and prescription drugs. Drinking cranberry juice a minimum of three times per day during treatment of a bladder infection will increase the need to urinate. This helps your body to rid itself of the infection through ingestion and expulsion of fluids.

Pharmacology of Cranberry

The use of cranberry for medicinal purposes has been the subject of many scientific discussions. At first, it was thought that acidification of the urine assisted in creating an antibacterial effect. However, the primary reason that cranberry works so well for treating bladder infections is its prevention of bacterial adhesion to cell walls. It also prevents adherence by other gram-negative uropathogens that cause infection. Cranberry's ability to inhibit the adherence of bacteria has been shown through in vitro research.

Other Uses

One study showed that the same property in cranberry juice that prevents bladder infections also aids in dental plaque prevention. Additionally, cranberry has been discovered to be a recommended treatment for Candida (yeast) infections.

Further in vitro studies show that cranberry has an inhibiting effect on certain types of fungi. However, there are no human trials that indicate its effectiveness in treating fungal infections when used alone.

Symptoms of a Bladder Infection

The most common symptom of an oncoming bladder infection is feeling a constant, urgent need to empty the bladder. This feeling is present even when there is little or no fluid in the bladder. Other symptoms may include:

* Frequent urination * Dysuria (burning or painful urination) * Bladder spasms * Cloudy urine * Bloody urine * Foul-smelling urine * Mild fever

A bladder infection that has gone untreated for an extended period of time could turn into a kidney infection. This brings with it much more serious symptoms which may include fever, chills and nausea. You may also experience cloudy or bloody urine, painful urination and abdominal pain. A common telltale sign of kidney infection is back pain just above the waist.

If you are experiencing any of these symptoms, it is wise to contact your physician. Bladder infection symptoms will not go away by themselves. They will continue to worsen, and your infection will become much more serious. Treatment for bladder infections is quick and easy. The sooner you begin the better.

If you suspect that you are about to experience a bladder infection, begin a regimen of drinking cranberry juice or supplement at least three times a day and make an appointment with your doctor.

Preventing Bladder Infections

There are several precautions you can take to prevent bladder infections. Some may seem obvious or silly, but after your first infection you will think very differently. Some of these precautions include:

* Wipe from front to back after urination or a bowel movement. This prevents the spread of bacteria.

* Go to the bathroom frequently. Holding urine in the bladder for long periods of time invites an infection.

* Keep the genital area clean and dry. Avoid prolonged moisture in the area.

* Avoid frequent bubble baths. They can cause vaginal irritation.

* Try to urinate soon after sexual activity. If lubricants are used, use only those that are water-soluble.

* Underwear with a cotton crotch will aid in infection prevention as well.

Drink a lot of water throughout the day. Also, drink cranberry juice or cranberry supplement to keep the urine acidic. This will prevent natural bacteria from multiplying as frequently, thus avoiding bladder infection.

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Broken Cell Chlorella - Single Celled Micro alga
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Date: April 21, 2008 05:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Broken Cell Chlorella - Single Celled Micro alga

Chlorella is what is known as a micro alga, a single celled vegetable organism that grows in fresh water. Microalgae are microscopic species of plant life that are likely responsible for the biological evolutionary history of our planet. Most people associate algae with seaweed: marine plant life. However, this is a restricted view since algae are also common on land, although are rarely conspicuous and still require an aqueous environment if not necessarily a salt water ocean.

The reason for this is that algae have no vascular tissue to draw moisture up into the body of the plant as terrestrial plants do, and they tend to be found in tropical regions, on snow in areas of the Arctic and also on exposed areas of stone and rock in symbiosis with fungi in the form of lichens. They can also be found in freshwater ponds and rivers, and chlorella is one of these.

Its scientific name is Chlorella pyrenoidosa, and it occurs worldwide. It is said to have the highest concentration of chlorophyll of any other known plant in addition to its other highly nutritional content. The superlatives are almost limitless for such a small plant that most of the general population is unaware of. It is the first plant known to have a true nucleus, it has been around for about two and half billion years, and it can multiply itself fourfold making it the fastest growing species of plant known on earth. It beats other fast-growing algae and bamboo out of site.

So what of its nutritional content? It is believed by NASA to be the ultimate foodstuff for long-term travel in space and an ideal crop for colonizing communities. Were a space community to be established on Mars, chlorella would be the first to be cultivated under these big glass domes we all see in the movies! It is more than just a foodstuff though; it is also the most powerful known natural detoxifier for the human body, which makes it practically the ideal food. Why is this?

If any food deserves to be referred to as a ‘superfood’ it is chlorella. It consists of over 60% bioavailable protein, and contains six members of the vitamin B complex (1, 2, 3, 5, 6, 12) and also vitamins A, C, E and K. It is therefore very high in antioxidants and excellent for destroying free radicals as soon as they are formed, and before they can cause problems such as atherosclerosis and excessive cell damage.

It also contains more than its fair share of minerals such as calcium, manganese, magnesium, phosphorus and zinc, and also iodine, folic acid and a high proportion of iron. That is not all: it contains many more nutrients essential for a healthy life, but above all chlorella contains all eight essential amino acids.

Human biochemistry and metabolism need 20 amino acids to function properly, twelve of which can be manufactured by the liver from these eight: leucine, isoleucine, lysine, methionine, phenylalanine, threonine, tryptophan and valine, and sometimes serine is added. These are called the essential amino acids from which all the others that your body needs can be manufactured.

Amino acids are needed to build proteins and DNA, manufacture body cells, repair damaged tissue, help the immune system to protect you from invading bacteria and viruses, ensure that the oxygen you breathe gets to the cells where it is needed to sustain life and carry out many other functions besides. Without them you could not exist. Chlorella contains five times more protein and amino acids than eggs do.

The Chlorella Growth Factor or CGF is a combination of these amino acids, together with nucleic acids, carbohydrates and peptides that have not yet been completely characterized. The CGF promotes the growth of body cells, and stimulates cell repair in a way not seen before in any other food. It has been shown to promote the growth of children in a natural and safe way.

Not only this, but it has been found not to promote the growth of diseased or cancerous cells, only healthy ones. The fact that that this accelerated growth does not happen with adults indicates that the Chlorella Growth Factor supports the natural growing process, although in adults it has been seen to accelerate the repair of damaged body tissue.

Chlorella also appears to strengthen the immune system, and researchers have found the presence of a polysaccharide in the cell walls of the microalgae that acts with CGF to produce an interferon that protects the helper cells that aid macrophages to destroy invading bacteria and viruses. It can help our resistance to influenza, choryza (common cold), fungi such as candida and many other forms of invasion by foreign agents into our bloodstream.

The detox effect of chlorella is largely contained within its cell walls that can bind with persistent toxic substances such as DDT, and bind with heavy metals to safely remove them from the body. In fact it is the ideal anti-toxin for life in today’s environment, full of vehicle exhaust fumes, pesticides and other chemical emissions. It has been claimed to be able to remove mercury from the body, but this has not been established.

Probably the only problem with the ingestion and the efficiency of the body to use Chlorella to its full extent is the strength of the cell walls. Chlorella has very strong cell walls, which could also account for the concentration of nutrients within them. the traditional method to overcome this was to mill them using small glass or ceramic beads to break the cell walls down, but the Japanese have come up with a more effective means. High frequency sound waves are used to break the cell walls down supersonically, a technique known as ‘cracking’, and once cracked the cells can release up to 65% of its nutrients, compared to the 50% of the milling method.

The nutritional content of single celled microalgae such as chlorella is amazing, and if the was only one food that you were able to eat, then this would be it. There is no other known species of plant or animal life that provides the range of vitamins, minerals, proteins and amino acids that chlorella does, and it truly is the king of all superfoods.



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Vitamin C Citations
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Date: May 28, 2007 11:49 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamin C Citations

What is it? The world’s best known water-soluble antioxidant vitamin; also known as ascorbic acid.

What does it do? Has aided anti-cancer therapy when used intravenously (under a practitioner’s supervision); ingestion of more commonly available dosages has been linked with both reduced cancer risk and lower risk of death from all causes.

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D-Ribose Powder Benefits!
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Date: April 10, 2007 11:57 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: D-Ribose Powder Benefits!

Benefits

Supports normal heart function*

A significant amount of in vitro, animal and human research suggests benefits of ribose on heart function.* Studies have shown that ribose supplementation can enhance cardiac energy levels and support cardiovascular metabolism.* Ribose has been shown in clinical trials to enhance the recovery of heart muscle ATP levels and improve myocardial function following exercise.

Studies suggest that ribose supplementation can increase the tolerability of the cardiovascular system to exercise-induced fatigue.1 In one study, twenty men underwent treadmill exercise tests on two consecutive days to confirm the onset of fatigue secondary to exercise. The participants were then randomized to the treatment group or a placebo group. The groups received either four doses of 15 grams of D-ribose (60 grams/day total) or the same amount of placebo each day. After three days of treatment, another treadmill test was performed. The time it took to reach the specified level of fatigue was significantly greater in the ribose group than in the placebo group.

Another study investigated the ability of ribose to support healthy heart function and quality of life.2 In a randomized, crossover design study, fifteen individuals were given 5 grams three times a day of either D-ribose or placebo. Each treatment period lasted three weeks. In patients receiving ribose, echocardiography demonstrated enhancement of heart function, reflecting a “more efficient relaxation phase of the heart”. Participants also had a significant improvement in their subjective quality of life scores compared to placebo.  

Scientists suggest that suboptimal heart function is a result of the heart requiring more energy to function properly. Ribose supports the heart’s enhanced energy requirements, promoting optimal heart function. It does so by enhancing the stores of high-energy phosphates in heart tissue. These intermediates are necessary for the production and resynthesis of ATP. A double-blind crossover study in which 12 individuals were randomized to receive either ribose or dextrose (both administered as 5 grams three times daily for three weeks, followed by a 1-week washout period and crossover of treatments for three additional weeks) suggested significant enhancements in normal cardiac function during the period of ribose supplementation.3

Perhaps one of the more useful illustrations of the potential for ribose to support heart function comes from a study in which 20 rats received a continuous infusion of ribose for 24 hours (control rats received an infusion of saline). The hearts were then explanted (as they would be for heart transplants) and placed in preservation solution that was enriched with ribose for 4 hours. ATP levels were measured from tissue biopsies and revealed that 10 of the ribose-treated hearts had ATP levels higher than 12.3 micromoles per gram whereas saline-treated hearts (controls) had lower ATP levels, with 20% showing levels below 10 micromoles per gram of tissue. This provides support for the hypothesis that ribose may enhance the preservation of ATP levels in cardiac tissue, promoting normal heart function.4

Further animal studies have shown that ribose significantly enhances heart function after experimentally induced cardiac depression. Rats were injected with isoproterenol (a drug that stimulates sympathetic nervous system function) and had their abdominal aorta constricted to induce depression of heart function and reduce cardiac ATP levels. The decrease in ATP was primarily responsible for the depression of heart function. Continuous infusion of ribose for 24 hours replenished ATP concentrations to normal levels and normalized heart function in these animals.5

Ribose may strengthen and support the body’s crucial antioxidant defenses*

Ribose may support the body’s innate antioxidant mechanisms while promoting an antioxidant effect of its own. Intense exercise and other strenuous activity can induce the production of free radicals. Preliminary studies suggest that ribose can attenuate some of the effects of oxidation seen after performance of intensive exercise.

One small human study indicated that ribose administered at a dose of seven grams before and after a bout of cycling exercise may reduce free radical production.6 Seven volunteers ingested either ribose or placebo both before and after intense exercise. Markers of lipid peroxidation, including malondialdehyde, significantly decreased in the ribose-supplemented group, while increasing in the control group. The results of this study indicate a possible effect of ribose in supporting antioxidant activity.

Supports healthy energy levels in heart and muscle tissue*

After bouts of intense exercise, ATP levels have been shown to decrease by an average of 15 to 20%.7 The amount of ATP stored in the muscle is limited and so the body must have the potential to rebuild ATP stores. ATP is the fuel necessary for the integrity and function of a cell. In addition, several studies have found correlations between ATP content and heart function.1 Research that was also alluded to above suggests that ribose stimulates ATP synthesis and supports heart and muscle function by enhancing ATP levels in cardiac and muscle tissue. D-ribose is an essential building block for the synthesis of ATP through the pentose phosphate pathway. 

The results of ribose supplementation enhancing ATP levels in muscle are evidenced by studies suggesting beneficial effects on anaerobic performance. In a randomized, placebo-controlled crossover study assessing the effects of acute ribose supplementation, participants receiving the ribose supplement had increases in mean power (a measure of average overall muscular strength output during the sprint) and peak power (a measure of the highest muscular strength output during the sprint) when undergoing a series of cycle sprints.8 While this effect was not noted in all of the six short cycling sprints that the participants underwent, the study does illustrate the potential benefits of ribose on ATP production and, secondarily, on enhancing exercise performance.

A second placebo-controlled trial investigated the effects of four weeks of ribose-supplementation (10 grams /day) on male bodybuilders. Of the 20 participants who were recruited, twelve completed the study. Each subject participated in a heavy-resistance training program designed to increase skeletal muscle mass. The effects of ribose on body composition (body weight, body fat, lean body mass, fat mass, and bone mineral content) were also assessed. The results suggested that ribose increased total work capacity and bench press strength compared to placebo, without altering body composition.9

Supports energy recovery after exercise*

Animal studies have suggested that the administration of ribose after exercise increases the rate of adenine salvage by five to seven-fold in muscle tissue7, supporting energy recovery after exercise. When ATP is utilized by muscle tissue, the degradation products include adenine nucleotides (Adenine is one of two purine bases that is a component of DNA). Adenine is recycled to synthesize DNA, and the salvage of adenine within the muscle tissue is crucial to energy recovery. Studies have shown that the presence of adequate ribose concentrations is the rate-limiting step in the purine salvage pathway. Therefore, increased adenine salvage could potentially help in the recovery and regeneration of ATP after intense bouts of activity.

A study investigated the effect of oral intake of ribose on the synthesis of AMP, a precursor to ATP.10 Participants performed intense cycle training for seven days. They then received either ribose (at a concentration of 200 mg/kg body weight, which is equivalent to 14 grams per day for an average 70 kilogram male) or placebo three times a day for the following three days. Exercise tests were performed again on day 4. Muscle biopsy samples were taken before the first training session, immediately after, and again five hours, 24 hours, and 72 hours after the last training session. No differences were seen in exercise performance between the groups. The intense exercise caused the ATP levels in muscle to decrease in both groups. However, at 72 hours post-exercise, the ribose group exhibited a much higher ATP level than the placebo group. The muscle levels of critical building blocks for ATP, including total adenine nucleotides (TAN) and inosine 5’-monophosphate (IMP), were also significantly higher in the ribose group compared to the placebo group at 24 hours after exercise. Ribose-supplementation was shown to enhance the resynthesis of ATP after intense exercise.

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Safety

Caution: Insulin-dependent diabetics and pregnant women should consult their physician before use.

Suggested Adult Use: Take 1 or 2 scoops mixed in water, juice or other beverage two times per day. May be taken with or without food.

Scientific References

1) Pliml, W., von Arnim, T., Stablein, A., Hofmann, H., Zimmer, H., Erdmann, E. Effects of ribose on exercise-induced ischaemia in stable coronary artery disease. The Lancet. 1992;340:507-510.

2) Omran, H., Illien, S., MacCarter, D., St. Cyr, J.A., Luderitz, B. D-Ribose improves diastolic function and quality of life in congestive heart failure patients: a prospective feasibility study. The European Journal of Heart Failure. 2003;5:615-619.

3) Illien, S., Omran, H., MacCarter, D., St. Cyr, J.A. Ribose improves myocardial function in congestive heart failure. FASEB Journal 2001;15(5): A1142

 

4) Muller C., Zimmer H., Gross M., Gresser U., Brotsack I., Wehling M., Pliml W. Effect of ribose on cardiac adenine nucleotides in a donor model for heart transplantation. Eur J Med Res. 1998 Dec 16;3(12):554-8.

5) Zimmer H.G. Normalization of depressed heart function in rats by ribose. Science. 1983 Apr 1;220(4592):81-2.

6) Seifert, J.G., Subudhi, A., Fu, M., Riska, J.J. The effects of ribose ingestion on indices of free radical production during hypoxic exercise. Free Rad Biol Med 2002; 33(Suppl 1) S269.

7) Zarzeczny, R., Brault, J.J., Abraham, K.A., Hancock, C.R., Terjung, R. Influence of ribose on adenine salvage after intense muscle contractions. J Applied Physiology. 2001;91:1775-1781. 

8) Berardi J.M., Ziegenfuss T.N. Effects of ribose supplementation on repeated sprint performance in men. J Strength Cond Res. 2003 Feb;17(1):47-52.

9) Van Gammeren, D.V., Falk, D., Antonio, J. The effects of four weeks of ribose supplementation on body composition and exercise performance in healthy, young, male recreational bodybuilders: a double-blind, placebo-controlled trial. Current Ther Research. 2002;63(8):486-495.

10) Hellsten, Y., Skadhauge, L., Bangsbo, J. Effect of ribose supplementation on resynthesis of adenine nucleotides after intense intermittent training in humans. American Journal of Physiology – Regulatory, Integrative and Comparative Physiology. 2004;286:R182-R188.



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EpiCore Benefits
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Date: April 09, 2007 05:02 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: EpiCore Benefits

Benefits

EpiCor® is a unique and novel dietary supplement used for support of immune health, with a fascinating history of discovery. In 1943, a company in Cedar Rapids, Iowa called Diamond V Mills, Inc. began manufacturing and selling a fermentation product from the yeast Saccharomyces cerevisiae, the same yeast used in bread and beer making. The product was and still is used as an additive for animal feed to help improve digestion as well as overall health in animals. It has been on the market for over 60 years.

Interestingly, when the company became self-insured, they became aware of unusually low rates of illness in employees that worked in the manufacturing plant for this animal product. This led to very low increases in their insurance premiums over the years compared to other companies, saving them quite a lot of money. Hence they began to investigate what might be the cause of the “healthfulness” of the employees at the fermentation plant. This investigation and subsequent research studies led to the formation of a new company called Embria Health Sciences, which now produces EpiCor® as a supplement for humans to support immune system health.1 Doctor’s Best® is proud to now offer the benefits of EpiCor® to its customers.

Beneficial Support of the Immune System and Activation of Natural Killer (NK) Cells in vitro*

A comparison study was performed on blood from 10 fermentation plant workers compared to that from 10 age and gender matched controls. The fermentation plant workers had several immune cell parameters that appeared superior to the control group. These included decreased levels of CD8 cells resulting in significantly increased CD4 to CD8 ratios, significantly improved cytotoxic natural killer (NK) cell activity even though total NK cells were decreased in number, higher killing efficiency of NK cells, significantly increased levels of secretory IgA, increased numbers of EpiCor™ specific antibodies, higher levels of red blood cell intracellular glutathione, and significantly lower levels of immune complexes. These results represent benefits on various cellular players of both the specific and innate parts of the immune system.1,3,4

NK cells are one of the first lines of defense used by the immune system. An in vitro study performed on human cells showed that NK cells were activated after incubation with EpiCor®, as evaluated by expression of the CD69 activation marker. The CD25 marker (IL-2 receptor) was also induced in the NK cells, although to a lesser degree.1,2 B cell activation was also noted through increased expression of CD80 and CD86 markers.2 Immediate increases in calcium levels were evident in peripheral blood mononuclear cells after exposure to EpiCor®, suggesting increased activation through calcium regulation.2

High Metabolite Immunogen*: Nutrient Make-up

Production of EpiCor® utilizes the common and harmless bakers or brewers yeast Saccharomyces cerevisiae in a patented process called MetaGen4™, a multi-stage fermentation and drying process. It differs from other yeast products in that it contains both the yeast itself as well as the metabolites or “nutrilites” formed by the fermentation process, which are present in the media.1 Together the media containing the metabolites and the yeast are dried to form EpiCor®. Analysis of EpiCor® reveals that it contains a mixture of natural polyphenols, phytosterols, beta-glucans, mannan oligosaccharides, fiber, trace amounts of B vitamins and minerals, as well as a host of other nutritional compounds.1,2

Beneficial Antioxidant Activity*

EpiCor® was tested for antioxidant activity in an in vitro assay called the Oxygen Radical Absorbance Capacity assay (ORAC). In this assay, EpiCor® was shown to have a total ORAC antioxidant level of 610 micromol TE (tocopherol (vitamin E) equivalents) units (ORAC units) per gram dry weight, which soared above other high antioxidant level foods such as cranberries (93 ORAC units per gram dry weight) and blueberries (62 ORAC units per gram dry weight).1,3,5

In another study, freshly isolated human neutrophils were treated with EpiCor® followed by the free radical generator hydrogen peroxide. Cells were treated with a dye that fluoresces when attacked by free radicals. Those cells treated with EpiCor® showed decreased fluorescence intensity compared to control cells not treated with EpiCor®, verifying antioxidant activity in vitro.2

Safety

Numerous safety tests have been conducted on EpiCor®, revealing an extremely safe profile. Animal studies performed by a leading toxicology laboratory showed no indication of any toxic effects of EpiCor®. An acute oral toxicity study on 20 rats showed that the product was safe when given to rats at a single oral dose of 2000 milligrams per kilogram of body weight (equivalent to a human ingesting 280 capsules at once). After 2 weeks the rats showed no clinical symptoms, no deaths, no abnormalities in body weight, and no gross pathological changes. The same safety results were found in a subchronic toxicity study where rats were given up to 1500 milligrams daily for 90 days (equivalent to a human ingesting up to 210 capsules daily for 1.5 years). Again, absolutely no signs or symptoms of toxicity were noted in these animals.1,3

In addition, a standard bacterial reverse mutagenicity test (AMES test) as well as a mammalian cell mutation assay using mouse lymphoma cells revealed no evidence of any increase in mutation rates after exposure to EpiCor®. EpiCor® also showed no evidence of mitogenicity (inducing increased cell division) in a human lymphocyte proliferation assay. This suggests that EpiCor® does not cause over-reactivity of cells1,3.

The effect of EpiCor® on specific liver enzymes CYP1A2 and CYP3A4 (enzymes involved in metabolizing certain drugs and other compounds) was assessed. Immortalized hepatocytes (liver cells) were treated with various concentrations of EpiCor® and compared to both positive and negative controls. EpiCor® did not increase the expression or activity of the liver enzymes, suggesting that it may not affect the metabolism of other substances or medications metabolized by these enzymes if they are taken simultaneously. It also did not appear to be toxic to the cells as measured by lactate dehydrogenase assays and microscopic analysis.1

Lastly, EpiCor® was tested for safety in humans in an open label study on 15 adult men and women given a single 500 milligram dose for 30 days. On various days throughout the study vital signs were monitored, and blood and urine samples were analyzed. No clinically relevant abnormal effects on the participants were found1.

 

EpiCor® also currently has received self-affirmed Generally Regarded as Safe (GRAS) status by an expert panel that included eminent toxicologists1.

 

EpiCor® is a novel compound with an incredibly unique composition that has been shown to enhance immune system function.*

Suggested Adult Use: Take one capsule daily with or without food.

 

 

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

 

Scientific References

1. Embria Health Sciences

2. Hart et al. A new Saccharomyces cerevisiae based product has anti-inflammatory effects while specifically activating human NK and B lymphocyte subsets. Unpublished study, personal communication.

3. Schauss AG, Jensen G, Vojdani A, Financsek I. After decades of ingestion by farm animals, the discovery of a yeast fermentate with unexpected significant immune modulatory activity when consumed by humans. [abstract] Journal of the American College of Nutrition, 2006; 25(5): 465.

4. Schauss AG, Vodjani A. Discovery of an edible fermentation product with unusual immune enhancing properties in humans. [abstract] FASEB J, 2006; 20(4):A143.

5. Wu X, Beecher GR, Holden JM, Haytowitz DB, Gebhardt SE, Prior RL. Lipophilic and hydrophilic antioxidant capacities of common foods in the United States. J Agric Food Chem 2004 Jun 16;52(12):4026-3



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How Does It Work?
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Date: July 08, 2006 01:24 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does It Work?

Proprietary Probiotic blend

Acidophilus Pearls is a probiotic dietary supplement designed to help support digestion and a healthy intestinal system. Probiotics, such as lactobacillus acidophilus and Bifidobacterium longum are live microbial food supplements that are non-toxic and do not cause disease (non-pathogenic). Probiotics do not permanently colonize in the body. Therefore, they need to be ingested regularly for their health-promoting effects to persist. After ingestion, probiotics must adhere to the wall of the intestine. Once attached to the intestinal wall, the bacteria are capable of multiplying and colonizing in the gut, thereby enhancing the immune response. 1-3

Oral probiotics help support the composition and metabolic activities of the large intestine micro flora.1 Micro flora of the large intestines assist digestion through fermentation (making the intestines inhospitable to invading species), protection against pathogenic bacteria, and stimulation of the development of certain components of the immune system.3 Lactobacillus acidophilus and Bifidobacterium longum occupy a central role in the guy micro flora, thereby enabling them to influence the composition of the micro flora to provide health benefits.4

Breakdown of Lactose

Lactose is an important sugar that is converted to lactic acid by lactic acid producing bacteria (such as lactobacillus acidophilus and Bifidobacterium longum).6 Lactose intolerance results from an inability to digest lactose.7 Lactose intolerance may be due to genetics, age related declines in intestinal lactase (the enzyme that metabolizes lactose), or other reasons.8 Lactase deficient people accumulate non-absorbed lactose in the gastrointestinal tract, which draws water and electrolytes into the gut and accelerates transit time, which can lead to diarrhea.2,8 Lactic acid bacteria can help metabolize the non-absorbed lactose in the gastrointestinal tract.

In a randomized, controlled clinical trial, Bifidobacterium longum was shown to support the breakdown of lactose and reduce the symptoms of lactose intolerance (flatulence) in people with lactose intolerance.5

Immune system support

While a normal micro flora is associated with good health, changes in intestinal health are associated with altered immune function. A well-functioning gastrointestinal immune system mediates immune responsiveness at mucosal sites and throughout the entire body via the control of quality and quantity of foreign substances gaining access to the immune system.9

Lactobacillus acidophilus and Bifidobacterium longum have shown to possess immunoprotective/immunomodulatory properties. These benefits include modulation of: cytokine and various interleukin production, autoimmunity, natural killer cells cytotoxicity, lymphocyte proliferation, and antibody production.3

In an open, randomized, controlled trial, Lactobacillus acidophilus and Bifidobacterium bifidum were supportive of colon health in older adults. In addition, B cell (important antibody producing immune cells) levels increased as compared with the untreated group. The probiotics were very well tolerated, with no significant side effects or variations in clinical chemistry or hematologic parameters.

Decrease Occasional Constipation

Constipation is defined as infrequent or difficult defection that can result from decreased motility of the intestines. It is a common problem, particularly in older adults. When the feces remain in the large intestine for prolonged periods, there is excessive water absorption, making the feces dry and hard.7

Insufficient amounts of lactobacillus acidophilus and Bifidobacterium longum may play a role in delayed bowel movement, which can favor the activity of undesireable putrefactive bacteria (bacteria that break down organic matter into potentially harmful compounds) in the intestines. Lactic acid bacteria contribute to the re-establishemtn of healthy intestinal flora (at the expense of pathogen growth) and stimulation of intestinal peristalsis via lactic acid. 10

Support of putrefactive Processes

When unbalanced conditions are present in the intestines (ie, unbalanced diet, high acidity, and/or low levels of lactic acid bacteria), organic matter may be putrified (decomposed or rotting) by certain bacteria and produce harmful substances such as ammonia.1,11

Micro flora or the large intestines promote homeostasis (balance) in both the intestine and the vagina.1,12,13 these activities are carried out via support of direct production of antibodies, competition with adhesion to intestinal cells, or indirect modulation of the immune system.2

Support Digestion

Normal micro flora of the large intestine help support and complete digestion via fermentation.1,11 The risk of diarrhea, for example, increases when the capacity of colonic micro flora to ferment carbohydrates decreases.8 Oral ingestion of probiotics produces a stabilizing effect on the guy flora.2

Additional Benefits

The benefits of probiotics extend beyond digestion support and immune support. Lactobacillus acidophilus and Bifidobacterium longum also help support the better utilization and bioavailability of nutrients, including vitamins, minerals, proteins, fats, and carbohydrates.14

Candida albicans is a fungus that is a naturally occurring component of normal gastrointestinal micro flora.15 however, C. albicans should be maintained at healthy levels. Probiotics have been shown to help retain healthy levels of C. albicans that are already within normal limits.

True Delivery Technology

Recently, our Enzymatic Therapy laboratory tested four leading probiotics nutritional supplements in the marketplace. These supplements were best selling brands, two of the supplements were enteric coated, and all had label guarantees about potency (guaranteed number of live bacteria). The laboratory scientist counted the levels of living bacteria found in compared these findings to the bacterial levels claimed by each manufacturer. The products were also subjected to a simulation of stomach acid conditions, after which the levels of living bacteria were re-counted.

The laboratory results found the probiotic supplements contained less than 50% of the number of living bacteria that they clamed on their labels. Furthermore, the laboratory results found that only 10% of the liver bacteria clamed on the manufacturer’s label survived the simulated stomach conditions.

Acidophilus pearls used a revolutionary proprietary “pearl” encapsulation process called True Delivery Technology. The True Delivery Technology is a special type of natural coating that protects the probiotic bacteria.

The True Delivery is a seamless “pearl”, which consists of three layers. The inner layer is a paste of probiotic bacteria suspended in a protective oil suspension. The second layer actually “seals” the bacteria in the capsule, which protects them from air, moisture, and the effects of heat. Probiotic bacteria are anaerobic organisms (grow in the absence of oxygen) and the presence of oxygen can actually injure or kill them. Because probiotic bacteria are injured or destroyed by the acids of the stomach, the third, outermost layer of the pearl is specially developed to only dissolve in the alkaline environment of the intestines. This patented gelatin pearl protects the probiotic bacteria from the acid environment of the stomach, so that they can successfully reach the intestine.

The patented seamless pearl capsule of Acidophilus Pearls assures the virtually all the bacteria remain uninjured and healthy to colonize in the intestine. In addition, the special pearl capsule’s ability to seal the bacteria inside it eliminates the need for the nutritional supplement to be refrigerated – though they can be kept in the refrigerator, if desired.

Storage recommended

Store at controlled room temperature, 59 degrees F to 86 degrees F (15 – 30C). May refrigerate if desired

This statement has not been evaluated by the food and drug administration. This product is not intended to diagnose, treat, cure, or prevent any disease.



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Scientific References
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Date: February 11, 2006 09:30 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Scientific References

Scientific References 1. Toyoda-Ono Y, Maeda M, Nakao M, Yoshimura M, Sugiura-Tomimori N, Fukami H. 2-O-(beta-D-Glucopyranosyl)ascorbic acid, a novel ascorbic acid analogue isolated from Lycium fruit. J Agric Food Chem. 2004 Apr 7;52(7):2092-6.

2. Breithaupt DE, Weller P, Wolters M, Hahn A. Comparison of plasma responses in human subjects after the ingestion of 3R,3R'-zeaxanthin dipalmitate from wolfberry (Lycium barbarum) and non-esterified 3R,3R'-zeaxanthin using chiral high-performance liquid chromatography. Br J Nutr. 2004 May;91(5):707-13.

3. Cheng CY, Chung WY, Szeto YT, Benzie IF. Fasting plasma zeaxanthin response to Fructus barbarum L. (wolfberry; Kei Tze) in a food-based human supplementation trial. Br J Nutr. 2005 Jan;93(1):123-30.

4. Wu SJ, Ng LT, Lin CC. Antioxidant activities of some common ingredients of traditional chinese medicine, Angelica sinensis, Lycium barbarum and Poria cocos. Phytother Res. 2004 Dec;18(12):1008-12.

5. Zhao H, Alexeev A, Chang E, Greenburg G, Bojanowski K. Lycium barbarum glycoconjugates: effect on human skin and cultured dermal fibroblasts. Phytomedicine. 2005 Jan;12(1-2):131-7.

6. Gan L, Zhang SH, Liu Q, Xu HB. A polysaccharide-protein complex from Lycium barbarum upregulates cytokine expression in human peripheral blood mononuclear cells. Eur J Pharmacol. 2003 Jun 27;471(3):217-22.

7. Gan L, Hua Zhang S, Liang Yang X, Bi Xu H. Immunomodulation and antitumor activity by a polysaccharide-protein complex from Lycium barbarum. Int Immunopharmacol. 2004 Apr;4(4):563-9.



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Vitamin C FAQ's
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Date: December 27, 2005 05:11 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamin C FAQ's

Vitamin C FAQ's

What is Calcium Ascorbate?

Calcium Ascorbate is a buffered salt (mineral) form of the water-soluble antioxidant Vitamin C (ascorbic acid). Calcium is reacted with ascorbic acid to buffer the acidic nature of this vitamin, making it more gentle for the special needs of those who may have a sensitive gastrointestinal tract. The pH of this buffered mineral Ascorbate is approximately 6.8—7.4 as compared to ascorbic acid that is about a pH of 2.5. Calcium Ascorbate provides approximately 10% elemental calcium.

What does Calcium Ascorbate do?

Ascorbate (vitamin C) is a reducing sugar (has a reactive ene-diol structure) that is involved in biochemical processes such as hydroxylation of proline and lysine utilized in the formation of collagen and healthy connective tissue. A deficiency in Ascorbate results in a disease called scurvy which manifests as weakened collagen fibers, rotting teeth, delayed healing and open sores on the skin. Ascorbate is involved in many other vital functions such as the mobilization of iron, stimulation of immune system and as an anti-oxidant for scavenging of reactive free radicals.

Is this a necessary vitamin or can our bodies make enough to satisfy our needs?

Many plants and animals do not need to consume foods high in ascorbic acid to meet their need for Vitamin C because they are genetically programmed to produce enzymes that convert glucose into ascorbic acid. Unfortunately humans have only 3 of the 4 enzymes necessary for internal production of ascorbic acid, therefore we must satisfy our physical needs for this important vitamin through our intake of foods rich in vitamin C and/or take a good supplement.

What is the function of the Citrus Bioflavonoids?

Bioflavonoids are biologically active Flavonoid compounds found throughout the entire plant kingdom. Since the discovery of Flavonoids in 1936 when they were first isolated from lemons and called citrin and Vitamin P over 4,000 different types have been characterized. Though there are several forms of Bioflavonoids in the complex the predominant form is Hesperidin. These Flavonoids exhibit beneficial effects on capillary permeability and therefore support blood flow. They are antioxidants that work synergistically with Vitamin C as well as exhibiting anti-inflammatory activity.

Why are there color variations in your different Vitamin C products, and are they safe to take?

Most natural Vitamin C products vary in color from batch to batch and bottle to bottle. There are normally variations in the color of the raw material used during manufacturing, which is a normal occurrence. This is due to natural color variations in the source of the Vitamin C – generally, you will find C supplements to range in color from a light tan color to a light gray color.

Over the course of the shelf-life of a Vitamin C supplement, oxidation can cause a slight change in color, so you may find the light tan C-1000 you bought has changed to a darker tan six months later. This is a normal occurrence, and the product is safe to use up until the expiration date, and even beyond. NOW® is generally conservative with expiration dates, so a Vitamin C product is still safe after the date, it just may not be as effective due to oxidation.

Why does your Ester-C Complex say 625mg on the front of the label but list 500mg on the Supplement Facts panel? The key word is “complex”. Ester-C Complex is a combination of ascorbic acid (natural Vitamin C) and Calcium Ascorbate, which ultimately yields 500 total mg of Vitamin C. It is complexed with Calcium Ascorbate and other metabolites for greater absorption and faster utilization by your body. So the total complex is 625mg of Ester-C Complex, which yields 500mg of natural Vitamin C as ascorbic acid.

NOW Ester-C Pure Powder states the serving size is ½ teaspoon. How much Vitamin C am I getting with this serving size? ½ teaspoon of Ester-C Pure Powder is equivalent to 2000mg of natural Vitamin C and 250mg of Calcium.

Can I pour the powder in NOW® Vitamin C capsules into a liquid instead of swallowing the capsule? Many people do not want to or cannot swallow capsules, tablets or softgels, for various reasons. Encapsulated Vitamin C products from NOW® can be opened and dumped into a liquid for consumption. Juice or water is recommended if you choose this method. However, taking Vitamin C with water on an empty stomach is the recommended method of ingestion. We do not recommend trying this method with Vitamin C in tablet form, although you can grind or smash a tablet into powder form and add to water or juice. If you choose to do this, use a mortar and pestle for best results and minimal loss of product. Why go through the trouble when NOW® carries Vitamin C in a powdered form already. Save yourself time and trouble by ordering this form instead. Disclaimer: This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

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Carnitine Creatinate
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Date: December 08, 2005 03:33 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Carnitine Creatinate

Carnitine Creatinate

Neil E. Levin, CCN, DANLA 6/30/05

LIKELY USERS: Athletes, Bodybuilders, Dieters, People who consume a lot of fat, People needing cardiovascular support (energy for the heart), People who need quick energy, especially for fast muscle response, People with muscle wasting problems (including the elderly), Weightlifters

KEY INGREDIENTS: L-Carnitine and Creatine Monohydrate

MAIN PRODUCT FEATURES: Carnitine Creatinate Monohydrate is a specialized form of Creatine bonded to L-Carnitine. Creatine is a compound natural to the human body that aids in the regeneration of ATP, the chemical energy used by muscle tissue. During exercise, large quantities of creatine are irreversibly consumed. Clinical studies have shown that oral supplementation with Creatine can increase the amount of Creatine available in muscles for ATP production. L-Carnitine is an amino acid that is necessary for the transfer of fatty acids into the fat-burning parts of the cell, facilitating energy production from fat. The combination of these two compounds can produce a synergistic effect, making NOW® Carnitine Creatinate an ideal energy supplement.

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: Carnitine and Creatinate Monohydrate is a patented ingredient that has been the subject of research studies. It is supported by the scientific staff in the laboratories of both NOW Foods and the raw material supplier, both of which have a mutual interest in protecting the integrity and efficacy of this product. Protected by U.S. Patent No. 5,994,581 (L-Carnitine Creatinate Monohydrate).

Look at the price: this is a better way to buy both supplements than purchasing them separately.

This formula is suitable for vegetarians and is offered in both tablet and powder forms.

SERVING SIZE & HOW TO TAKE IT: As a dietary supplement, every two tablets provide 1,000 mg. (one gram) each of both L-Carnitine and Creatine Monohydrate. Or one teaspoon provides 1,150 mg.) each of both L-Carnitine and Creatine Monohydrate. Take one or more servings per day with a carbohydrate source, such as fruit juice or sports drinks.

COMPLEMENTARY PRODUCTS: CoQ10, carbohydrates, B-Complex vitamins, chromium, vanadium, Hawthorn leaf and flower extract, protein supplements. Adaptogenic herbs: ginsengs, Eleuthero, Rhodiola, Maca, Ashwaganda, licorice root

CAUTIONS: none.

PRODUCT SPECIFIC: This product is very sensitive to moisture. Please keep in the original packaging or in a moisture resistant container. Do not take more than 20 grams per day. Discontinue use if cramps of stomach upset occur, especially if taking large doses. Do not take if kidney disease is present. Do not use large doses of caffeine with creatine, as it may increase the possibility of muscle cramping.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. When taking any new supplement, use common sense and cautiously increase to the full dose over time to avoid any potential problems.

Packages may contain moisture or oxygen controlling packets or canisters that are not intended for consumption. In order to maintain maximum freshness, please do not remove these from your bottle (until the bottle is empty). Please recycle your container.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

Fang S-M (1998) Carnitine Creatinate. U.S. Patent 5,994,581.

L-CARNITINE:

Beers MH, Berkow R (eds). The Merck Manual of Diagnosis and Therapy, 17th ed. Whitehouse Station, NJ: Merck and Co., Inc, 1999, 881-3.

Broquist HP (1994) Carnitine, in Modern Nutrition in Health and Disease, 8th ed., Shils ME, Olson JA, Shike M (eds.) Lea & Febiger, Philadelphia, pp. 459-465. Casey A, Greenhoff PL (2000) Does dietary creatine supplementation play a role in skeletal muscle metabolism and performance? Am J Clin Nutr 72(suppl):607S-17S. Columbani P, Wenk C, Kunz I, et al. Effect of L-carnitine supplementation on physical performance and energy metabolism of endurance-trained athletes: a double blind crossover field study. Eur J Appl Physiol 1996;73:434-9.

Dal Negro R, Pomari G, Zoccatelli O, Turco P. L-carnitine and rehabilitative respiratory physiokinesitherapy: metabolic and ventilatory response in chronic respiratory insufficiency. Int J Clin Pharmacol Ther Toxicol 1986;24:453-6.

Dal Negro R, Turco P, Pomari C, De Conti F. Effects of L-carnitine on physical performance in chronic respiratory insufficiency. Int J Clin Pharmacol Ther Toxicol 1988;26:269-72.

Del Favero A. Carnitine and gangliosides. Lancet 1988;2:337 [letter].

Dipalma JR. Carnitine deficiency. Am Fam Physician 1988;38:243–51.

Digiesi V, Palchetti R, Cantini F. The benefits of L-carnitine in essential arterial hypertension. Minerva Med 1989;80:227-31.

Giamberardino MA, Dragani L, Valente R, et al. Effects of prolonged L-carnitine administration on delayed muscle pain and CK release after eccentric effort. Int J Sports Med 1996;17:320-4.

Green RE, Levine AM, Gunning MJ. The effect of L-carnitine supplementation on lean body mass in male amateur body builders. J Am Diet Assoc 1997;(suppl):A-72.

Harris RC, Soderlund K, Hultman E (1992) Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation. Clin Sci 83(3):367-374.

Kendler BS. Carnitine: an overview of its role in preventive medicine. Prev Med 1986;15:373–90.

Kobayashi A, Masumura Y, Yamazaki N. L-carnitine treatment for congestive heart failure—experimental and clinical study. Jpn Circ J 1992;56:86–94.

Murray MT. The many benefits of carnitine. Am J Natural Med 1996;3:6-14 [review].

Tamamogullari N, Silig Y, Icagasioglu S, Atalay A. Carnitine deficiency in diabetes mellitus complications. J Diabetes Complications 1999;13:251–3.

Yesilipek MA, Hazar V, Yegin O. L-Carnitine treatment in beta thalassemia major. Acta Haematol 1998;100:162-3. CREATINE MONOHYDRATE: Almada A, Mitchell T, Earnest C. Impact of chronic creatine supplementation on serum enzyme concentrations. FASEB J 1996;10:4567.

Becque MD, Lochmann JD, Melrose DR. Effects of oral creatine supplementation on muscular strength and body composition. Med Sci Sports Exerc 2000;32:654-8.

Casey A, Constantin-Teodosiu D, Howell S, et al. Creatine supplementation favorably affects performance and muscle metabolism during maximal intensity exercise in humans. Am J Physiol 1996;271:E31-E7.

Earnest CP, Almada AL, Mitchell TL. High-performance capillary electrophoresis-pure creatine monohydrate reduces blood lipids in men and women. Clin Sci 1996;91:113-8.

Earnest C, Almada A, Mitchell T. Influence of chronic creatine supplementation on hepatorenal function. FASEB J 1996;10:4588.

Earnest CP, Snell PG, Rodriguez R, et al. The effect of creatine monohydrate ingestion on anaerobic power indices, muscular strength and body composition. Acta Physiol Scand 1995;153:207-9.

Felber S, Skladal D, Wyss M, et al. Oral creatine supplementation in Duchenne muscular dystrophy: a clinical and 31P magnetic resonance spectroscopy study. Neurol Res 2000;22:145-50.

Feldman EB. Creatine: a dietary supplement and ergogenic aid. Nutr Rev 1999;57:45–50.

Green AL, Hultman E, Macdonald IA, et al. Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in man. Am J Physiol 1996;271:E821–6.

Green AL, Simpson EJ, Littlewood JJ, et al. Carbohydrate ingestion augments creatine retention during creatine feeding in humans. Acta Physiol Scand 1996;158:195-202.

Greenhaff PL. Creatine and its application as an ergogenic aid. Int J Sport Nutr 1995;5:94-101.

Greenhaff PL. The nutritional biochemistry of creatine. J Nutr Biochem 1997;8:610-8 [review].

Greenhaff PL, Bodin K, Soderlund K, et al. Effect of oral creatine supplementation on skeletal muscle phosphocreatine resynthesis. Am J Physiol 1994;266:E725-30.

Greenhaff PL, Casey A, Short AH, et al. Influence of oral creatine supplementation on muscle torque during repeated bouts of maximal voluntary exercise in man. Clin Sci 1993;84:565-71.

Harris RC, Soderlund K, Hultman E. Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation. Clin Sci 1992;83:367-74.

Hultman E, Soderlund K, Timmons J, et al. Muscle creatine loading in man. J Appl Physiol 1996;81:232–7.

Juhn MS, O’Kane JW, Vinci DM. Oral creatine supplementation in male collegiate athletes: a survey of dosing habits and side effects. J Am Diet Assoc 1999;99:593–5.

Kreider RB, Ferreira M, Wilson M, et al. Effects of creatine supplementation on body composition, strength, and sprint performance. Med Sci Sports Exerc 1998;30:73-82.

Poortmans JR, Auquier H. Renaut V, et al. Effect of short-term creatine supplementation on renal responses in men. Eur J Appl Physiol Occup Physiol 1997;76:566–7.

Poortmans JR, Francaux M. Long-term oral creatine supplementation does not impair renal function in healthy athletes. Med Sci Sports Exerc 1999;31:1108–10.

Pritchard NR, Kaira PA. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;351:1252–3 [letter].

Sewell DA, Robinson TM, Casey A, et al. The effect of acute dietary creatine supplementation upon indices of renal, hepatic and haematological function in human subjects. Proc Nutr Soc 1998;57:17A.

Silber ML. Scientific facts behind creatine monohydrate as a sports nutrition supplement. J Sports Med Phys Fitness 1999;39:179–88 [review].

Sipila I, Rapola J, Simell O, et al. Supplementary creatine as a treatment for gyrate atrophy of the choroid and retina. N Engl J Med 1981;304:867-70.

Stone MH, Sanborn K, Smith LL, et al. Effects of in-season (5-weeks) creatine and pyruvate supplementation on anaerobic performance and body composition in American football players. Int J Sport Nutr 1999;9:146-65.

Stout JR, Eckerson J, Noonan D, et al. The effects of a supplement designed to augment creatine uptake on exercise performance and fat-free mass in football players. Med Sci Sports Exerc 1997;29:S251.

Tarnopolsky MA. Potential benefits of creatine monohydrate supplementation in the elderly. Curr Opin Clin Nutr Metab Care 2000;3:497-502 [review].

Tarnopolsky M, Martin J. Creatine monohydrate increases strength in patients with neuromuscular disease. Neurology 1999;52:854-7.

Tarnopolsky MA, Roy BD, MacDonald JR. A randomized, controlled trial of creatine monohydrate in patients with mitochondrial cytopathies. Muscle Nerve 1997;20:1502-9.

Toler SM. Creatine is an ergogen for anaerobic exercise. Nutr Rev 1997;55:21-5 [review].

Vandenberghe K, Gills N, Van Leemputte M, et al. Caffeine counteracts the ergogenic action of muscle creatine loading. J Appl Physiol 1996;80:452–7.

Vandenberghe K, Goris M, Van Hecke P, et al. Long-term creatine intake is beneficial to muscle performance during resistance training. J Appl Physiol 1997;83:2055-63.

Walter MC, Lochmuller H, Reilich P, Klopstock T, Huber R, Hartard M, Hennig M, Pongratz D, Muller-Felber W. Creatine monohydrate in muscular dystrophies: A double-blind, placebo-controlled clinical study. Neurology. 2000 May 9;54(9):1848-50. PMID: 10802796

Walter MC, Reilich P, Lochmuller H, Kohnen R, Schlotter B, Hautmann H, Dunkl E, Pongratz D, Muller-Felber W. Creatine monohydrate in myotonic dystrophy: a double-blind, placebo-controlled clinical study. J Neurol. 2002 Dec;249(12):1717-22. PMID: 12529796



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Immune Renew Fact Sheet
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Date: December 07, 2005 01:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Immune Renew Fact Sheet

Immune Renew Fact Sheet Neil E. Levin, CCN, DANLA 02/10/05

LIKELY USERS: Everyone seeking a healthy immune system; People on low carb diets or non-whole grain diets that are lacking dietary beta-glucans

KEY INGREDIENTS: Astragalus Root Extract Powder 70% polysaccharides (200 mg). Proprietary blend of 8 organically grown “medicinal mushrooms” (200 mg)

MAIN PRODUCT FEATURES: Vegetarian formula. Polysaccharides in these US-grown mushrooms grown on organic brown rice include 1,3 Beta-glucans and terpenoids. Beta-glucans may stimulate the immune system in different ways. Triterpenoids may act as mild anticoagulants. Each mushroom may have a different effect; for example, one may stimulate T-cells and another Natural Killer cells, aiding in immune defense. Mushrooms have reported beneficial effects on liver health and promoting normal cell growth.

ADDITIONAL PRODUCT INFORMATION: Some extracts from these kinds of mushrooms have been used medicinally in Japan and China. The mushrooms include Turkey Tail, Sun Mushrooms, Maitake, Cordyceps, Phellinus, Lion’s Mane, Reishi and Shiitake. The astragalus extract also contains naturally occurring astragalosides. Mushrooms may help maintain normal cholesterol and triglyceride levels

SERVING SIZE & HOW TO TAKE IT: For everyday use take one or two caps per day, either with meals or on an empty stomach.

COMPLEMENTARY PRODUCTS: Vitamin C to break down beta-glucan structures for better absorption, Inositol Hexaphosphate (IP-6), I3C, Pometrol, mixed carotenoids and antioxidants

CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. Do not take with AIDS drugs or if you have an autoimmune disease. Use with caution if using anticoagulants or blood pressure medication, as these mushrooms may have mildly synergistic effects to those drugs. Do not use if you have mold or mushroom allergies (or any sensitivities to mushrooms, cheese, etc.), which can potentially result in hives, rashes, breathing difficulties (including dry mouth or throat), stomach distress, diarrhea, or any other unusual side effect.

This information is based on my own knowledge and these references, but should not be used as diagnosis, prescription or as specific product claims.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

1. Hobbs C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995
2. Wasser SP, Weis AL. Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: a modern perspective. Crit Rev Immunol. 1999;19(1):65-96.
3. Wasser SP. Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl Microbiol Biotechnol. 2002 Nov;60(3):258-74. Epub 2002 Sep 10.
4. Nanba H, Hamaguchi AM, Kuroda H. The chemical structure of an antitumor polysaccharide in fruit bodies of Grifola frondosa (maitake). Chem Pharm Bull 1987;35:1162–8.
5. Yamada Y, Nanba H, Kuroda H. Antitumor effect of orally administered extracts from fruit body of Grifola frondosa (maitake). Chemotherapy 1990;38:790–6.
6. Nanba H. Immunostimulant activity in vivo and anti-HIV activity in vitro of 3 branched b-1–6-glucans extracted from maitake mushrooms (Grifola frondosa). VIII International Conference on AIDS, Amsterdam, 1992 [abstract].
7. Kubo K, Nanba H. Anti-hyperliposis effect of maitake fruit body (Grifola frondosa). I. Biol Pharm Bull 1997;20:781–5.
8. Adachi K, Nanba H, Otsuka M, Kuroda H. Blood pressure lowering activity present in the fruit body of Grifola frondosa (maitake). Chem Pharm Bull 1988;36:1000–6.
9. Jones K. Shiitake: A major medicinal mushroom. Alt Compl Ther 1998;4:53–9 [review].
10. Taguchi I. Clinical efficacy of lentinan on patients with stomach cancer: End point results of a four-year follow-up survey. Cancer Detect Prevent Suppl 1987;1:333–49.
11. Matsuoka H, Seo Y, Wakasugi H, et al. Lentinan potentiates immunity and prolongs survival time of some patients. Anticancer Res 1997;17:2751–6.
12. Guangwen Y, Jianbin Y, Dongqin L, et al. Immunomodulatory and therapeutic effects of lentinan in treating condyloma acuminata. CJIM 1999;5:190–2.
13. Jones K. Reishi mushroom: Ancient medicine in modern times. Alt Compl Ther 1998;4:256–66 [review].
14. Kammatsuse K, Kajiware N, Hayashi K. Studies on Ganoderma lucidum: I. Efficacy against hypertension and side effects. Yakugaku Zasshi 1985;105:531–3.
15. Jin H, Zhang G, Cao X, et al. Treatment of hypertension by ling zhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Nimmi H, Xiu RJ, Sawada T, Zheng C. (eds). Microcirculatory Approach to Asian Traditional Medicine. New York: Elsevier Science, 1996, 131–8.
16. Suzuki H, et al. Immunopotentiating Substances in Lentinus edodes Mycelial Extract(LEM)-- Activation of Macrophage and Proliferation of Bone Marrow Cell. Nippon Shokakibyo Gakkai Zasshi. Jul1988;85(7): 1430.
17. Suzuki H, et al. Inhibition of the Infectivity and Cytopathic Effect of Human Immunodeficiency Virus by Water-soluble Lignin in an Extract of the Culture Medium of Lentinus edodes Mycelia (LEM). Biochem Biophys Res Commun. Apr1989;160(1):367-73.
18. Gordon M, et al. A Placebo-controlled Trial of the Immune Modulator, Lentinan, In HIV-positive Patients: A Phase I/II Trial. J Med. 1998;29(5-6):305-30.
19. Li JF, et al. Study on the Enhancing Effect of Polyporus Polysaccharide, Mycobacterium Polysaccharide and Lentinan on Lymphokine-activated Killer Cell Activity in vitro. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih. Apr1996;16(4):224-26.
20. Li KR, et al. Anti-atherosclerotic Properties of Higher Mushrooms (a Clinico-experimental Investigation. Vopr Pitan. Jan1989;1:16-19.
21. Shouji N, et al. Anticaries Effect of a Component From Shiitake (An Edible Mushroom). Caries Res. Feb2000;34(1):94-98.
22. Levy AM. Eosinophilia and Gastrointestinal Symptoms After Ingestion of Shiitake Mushrooms. J Allergy Clin Immunol. May1998;101(5):613-20.
23. Zjawiony JK. Biologically active compounds from Aphyllophorales (polypore) fungi. J Nat Prod. 2004 Feb;67(2):300-10.
24. Oliva D. Cellular and physiological effects of Ganoderma lucidum (Reishi). Mini Rev Med Chem. 2004 Oct;4(8):873-9.
25. Ooi VE, Liu F. Immunomodulation and anti-cancer activity of polysaccharide-protein complexes. Curr Med Chem. 2000 Jul;7(7):715-29.
26. Borchers AT, Stern JS, Hackman RM, Keen CL, Gershwin ME. Mushrooms, tumors, and immunity. Proc Soc Exp Biol Med. 1999 Sep;221(4):281-93.
27. Mau JL, Lin HC, Chen CC. Antioxidant properties of several medicinal mushrooms. J Agric Food Chem. 2002 Oct 9;50(21):6072-7.
28. Hirasawa M, Shouji N, Neta T, Fukushima K, Takada K. Three kinds of antibacterial substances from Lentinus edodes (Berk.) Sing. (Shiitake, an edible mushroom). Int J Antimicrob Agents. 1999 Feb;11(2):151-7.
29. Rajewska J, Balasinska B. Biologically active compounds of edible mushrooms and their beneficial impact on health. Postepy Hig Med Dosw (Online). 2004 Oct 5;58:352-7.
30. Chang R. Functional properties of edible mushrooms. Nutr Rev. 1996 Nov;54(11 Pt 2):S91-3.
31. Lin ZB, Zhang HN. Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms. Acta Pharmacol Sin. 2004 Nov;25(11):1387-95. PMID: 15525457
32. Cheung NK, Modak S, Vickers A, Knuckles B. Orally administered beta-glucans enhance anti-tumor effects of monoclonal antibodies. Cancer Immunol Immunother. 2002 Nov;51(10):557-64. Epub 2002 Sep 20. PMID: 12384807
33. Shamtsyan M, Konusova V, Maksimova Y, Goloshchev A, Panchenko A, Simbirtsev A, Petrishchev N, Denisova N. Immunomodulating and anti-tumor action of extracts of several mushrooms. J Biotechnol. 2004 Sep 30;113(1-3):77-83. PMID: 15380649
34. Zhang YD, Shen JP, Zhu SH, Huang DK, Ding Y, Zhang XL. Effects of astragalus (ASI, SK) on experimental liver injury Yao Xue Xue Bao. 1992;27(6):401-6. Chinese. PMID: 1442065
35. Sheng BW, Chen XF, Zhao J, He DL, Nan XY. Astragalus membranaceus reduces free radical-mediated injury to renal tubules in rabbits receiving high-energy shock waves. Chin Med J (Engl). 2005 Jan;118(1):43-9. PMID: 15642225
36. Yesilada E, Bedir E, Calis I, Takaishi Y, Ohmoto Y. Effects of triterpene saponins from Astragalus species on in vitro cytokine release. J Ethnopharmacol. 2005 Jan 4;96(1-2):71-7. PMID: 15588652
37. Li C, Cao L, Zeng Q. Astragalus prevents diabetic rats from developing cardiomyopathy by downregulating angiotensin II type2 receptors' expression. J Huazhong Univ Sci Technolog Med Sci. 2004;24(4):379-84. PMID: 15587404
38. Wang SH, Wang WJ, Wang XF, Chen W. [Effect of Astragalus polysaccharides and berberine on carbohydrate metabolism and cell differentiation in 3T3-L1 adipocytes]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Oct;24(10):926-8. Chinese. PMID: 15553830
39. Shao BM, Dai H, Xu W, Lin ZB, Gao XM. Immune receptors for polysaccharides from Ganoderma lucidum. Biochem Biophys Res Commun. 2004 Oct 8;323(1):133-41. PMID: 15351712
40. Mao SP, Cheng KL, Zhou YF. [Modulatory effect of Astragalus membranaceus on Th1/Th2 cytokine in patients with herpes simplex keratitis]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Feb;24(2):121-3. Chinese. PMID: 15015443
41. Guo FC, Williams BA, Kwakkel RP, Li HS, Li XP, Luo JY, Li WK, Verstegen MW. Effects of mushroom and herb polysaccharides, as alternatives for an antibiotic, on the cecal microbial ecosystem in broiler chickens. Poult Sci. 2004 Feb;83(2):175-82.



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Chloride: The Forgotten Essential Mineral
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Date: November 20, 2005 07:54 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Chloride: The Forgotten Essential Mineral

Chloride: The Forgotten Essential Mineral

Chloride is an “essential” mineral for humans. It is abundant in ionic trace mineral preparations. It is a major mineral nutrient that occurs primarily in body fluids. Chloride is a prominent negatively charged ion of the blood, where it represents 70% of the body’s total negative ion content. On average, an adult human body contains approximately 115 grams of chloride, making up about 0.15% of total body weight.1 The suggested amount of chloride intake ranges from 750 to 900 milligrams per day, based on the fact that total obligatory loss of chloride in the average person is close to 530 milligrams per day. As the principle negatively charged ion in the body, chloride serves as one of the main electrolytes of the body. Chloride, in addition to potassium and sodium, assist in the conduction of electrical impulses when dissolved in bodily water. Potassium and sodium become positive ions as they lose an electron when dissolved and chloride becomes a negative ion as it gains an electron when dissolved. A positive ion is always accompanied by a negative ion, hence the close relationship between sodium, potassium and chloride. The electrolytes are distributed throughout all body fluids including the blood, lymph, and the fluid inside and outside cells.2 The negative charge of chloride balances against the positive charges of sodium and potassium ions in order to maintain serum osmolarity.

Pivotal Roles of Chloride in the Body

In addition to its functions as an electrolyte, chloride combines with hydrogen in the stomach to make hydrochloric acid, a powerful digestive enzyme that is responsible for the break down of proteins, absorption of other metallic minerals, and activation of intrinsic factor, which in turn absorbs vitamin B12. Chloride is specially transported into the gastric lumen, in exchange for another negatively charged electrolyte (bicarbonate), in order to maintain electrical neutrality across the stomach membrane. After utilization in hydrochloric acid, some chloride is reabsorbed by the intestine, back into the blood stream where it is required for maintenance of extracellular fluid volume. Chloride is both actively and passively absorbed by the body, depending on the current metabolic demands. A constant exchange of chloride and bicarbonate, between red blood cells and the plasma helps to govern the pH balance and transport of carbon dioxide, a waste product of respiration, from the body. With sodium and potassium, chloride works in the nervous system to aid in the transport of electrical impulses throughout the body, as movement of negatively charged chloride into the cell propagates the nervous electrical potential.

Deficiency of Chloride

Deficiency of chloride is rare. However, when it does occur, it results in a life threatening condition known as alkalosis, in which the blood becomes overly alkaline. A tedious balance between alkalinity and acidity is in constant flux, and must be vigilantly maintained throughout the entire body. Alkalosis may occur as a result of excessive loss of sodium, such as heavy sweating during endurance exercise, and in cases of prolonged vomiting and diarrhea. Symptoms include muscle weakness, loss of appetite, irritability, dehydration, and profound lethargy. Hypochloremia may result from water overload, wasting conditions, and extensive bodily burns with sequestration of extracellular fluids. In a situation in which infants were inadvertently fed chloride-deficient formula, many experienced failure to thrive, anorexia, and weakness in their first year of life.3

Excess Intake?

Excessive intakes of dietary chloride only occur with the ingestion of large amounts of salt and potassium chloride. The toxic effects of such diets, such as fluid retention and high blood pressure, are attributed to the high sodium and potassium levels.4 Chloride toxicity has not been observed in humans except in the special case of impaired sodium chloride metabolism, e.g. in congestive heart failure.5 Healthy individuals can tolerate the intake of large quantities of chloride provided that there is a concomitant intake of fresh water. Other situations in which increased blood levels of chloride are seen include diseases of improper waste elimination that occur in kidney diseases. Excess chloride is normally excreted in the urine, sweat, and bowels. In fact, excess urinary excretion of chloride occurs in high salt diets. Excessive intakes of chloride can occur in a person with compromised health in addition to an unhealthy diet. However, those that follow a healthy diet and lead an active lifestyle may need to consider supplementing their diet with this important mineral.

Chloride vs. Chlorine

The mineral supplement chloride is very different from the gas chlorine. While elemental chlorine is a dangerous gas that does not exist in the free elemental state in nature because of its reactivity, although it is widely distributed in combination with other elements. Chloride is related to chlorine however, as one of the most common chlorine compounds is common salt, NaCl. Chloride is a by-product of the reaction between chlorine and an electrolyte, such as potassium, magnesium, or sodium, which are essential for human metabolism. Chloride salts are essential for sustaining human metabolism and have none of the effects of isolated chlorine gas.

Sources of Chloride

Chloride occurs naturally in foods at levels normally less than 0.36 milligrams per gram of food. The average intake of chloride during a salt-free diet is approximately 100 milligrams per day. Unfortunately, chloride is found commonly combined with undesirable dietary sources. The most common of these negative sources is table salt. Table salt is made from a combination of sodium and chloride ions. Other unhealthful sources include yeast extracts, processed lunchmeats, and cheeses. Healthier sources of chloride include kelp (seaweed), ionic trace minerals, olives, rye, tomatoes, lettuce, and celery, although not in large enough amounts to supply the needs of an active adult.6 In its original form, however, chloride is leached from various rocks into soil and water by years of weathering processes. The chloride ion is highly mobile and is transported to closed basins, such as the Great Salt Lake, or oceans.7

Summary

Chloride is a highly important, vital mineral required for both human and animal life. Without chloride, the human body would be unable to maintain fluids in blood vessels, conduct nerve transmissions, move muscles, or maintain proper kidney function. As a major electrolyte mineral of the body, chloride performs many roles, and is rapidly excreted from the body. Active adults that eat a healthy diet devoid of salt and illnesses in which vomiting and/or diarrhea are profuse warrant the supplementation of additional chloride. Replacement of chloride is essential on a daily basis to maintain regular metabolic function. Chloride is safely utilized by the body, without negative health effects. Of the negative health effects that have been associated with diets high in chloride, these are mainly attributable to the accompanying sodium and potassium, two other electrolyte minerals to which chloride is often attached

--------------------------------------------------------------------------------

1 Wesson LG. Physiology of the human kidney. New York, NY, Grune and Stratton, 1969: 591

2 Weast RC, ed. CRC handbook of chemistry and physics, 67th ed. Boca Raton, FL, CRC Press, 1986.

3 Kaleita TA. Neurologic/behavioral syndrome associated with ingestion of chloride-deficient infant formula. Pediatrics 1986 Oct;78(4):714-5

4 Beard TC. A salt-hypertension hypothesis. J Cardiovasc Pharmacol 1990;16 Suppl 7:S35-8

5 Seelig M. Cardiovascular consequences of magnesium deficiency and loss: pathogenesis, prevalence and manifestations--magnesium and chloride loss in refractory potassium repletion. Am J Cardiol 1989 Apr 18;63(14):4G-21G

6 Altschul AM, Grommet JK. Food choices for lowering sodium intake. Hypertension 1982 Sep-Oct;4(5 Pt 2):III116-20

7 Gelb SB, Anderson MP. Sources of chloride and sulfate in ground water beneath an urbanized area in Southeastern Wisconsin (Report WIS01 NTIS). Chemical abstracts, 1981, 96(2):11366g.



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Source Naturals - From Formula to Implementation
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Date: August 20, 2005 11:45 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Source Naturals - From Formula to Implementation

“Overseeing and tracking the manufacture of approximately 500 different products is a challenging and very satisfying responsibility. I take pride in making sure all aspects of manufacturing—material rotation and pulling, mixing, wet granulation, milling, tableting, and encapsulation—run smoothly and efficiently. –Dale Nemecek, Manufacturing Supervisor

From Formula to Implementation

Source Naturals’ manufacturing team has an enormous responsibility: bringing to fruition the plans so carefully laid down on paper by our research and product development staff. Here’s how.

Premium Ingredients Because grinding or cutting increases the exposure of plants to light, heat and air, and can cause a powdered herb to degrade, whole herbs are milled on site. The result is fresher, more potent botanicals. Source Naturals also seeks to minimize excipients (non-active ingredients) in tablets and to use the most natural sources available. Vegetable gums bind ingredients together, vegetable fiber (cellulose) improves hardness and compressibility, and modified cellulose gum facilitates disintegration after ingestion. Only natural flavorings and sweeteners are used in our lozenges or chewable tablets. Our labels provide full disclosure of all ingredients and excipients.

Optimal Production Methods

Ingredients are pulled from our warehouse using first-in, first-out inventory practices. Batches of measured materials are processed according to individual specifications. For tablets, roller compaction improves granulation and milling decreases particle size. Wet granulation is used when appropriate as an alternative: active ingredients are blended with water and vegetable binder, dried, milled, and compressed on a tablet press. Tablets are coated with cellulose and polished, adding a smooth, attractive surface that protects them and makes them easier to swallow. Source Naturals also has the capacity for manufacturing and filling liquids, and for in house encapsulation.

Whole herbs are milled on site, resulting in fresher, more potent botanicals.



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Source Naturals - Continuous Quality Assurance
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Date: August 20, 2005 11:44 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Source Naturals - Continuous Quality Assurance

“I oversee all the inspections, tests, and document reviews performed by our dedicated Quality Control staff to ensure that nothing compromises the healthfulness and high quality of our products.” Norm Nelson, Ph.D., Quality Control Director

Continuous Quality Assurance

Our Quality Control Department includes staff trained in microbiological assays, heavy metal screening, analytical chemistry and Eastern and Western herbalism. They utilize procedures that go beyond minimum industry requirements to ensure product excellence. All raw materials and finished goods must meet our inspectors’ rigorous quality specifications at every stage of manufacturing.

Pure Raw Materials

Bulk raw materials must be accompanied by Certificates of Analysis provided by the vendors. They are sampled and inspected according to a long list of specifications, including appearance, color, odor, flavor, texture, absence of extraneous material, and potency of active constituents. Vitamins, minerals and amino acids are screened and/or tested for impurities, while materials, such as herbs, that are biological in origin are tested for microbiological contamination.

Bioavailable Manufactured Product Inspectors scrutinize finished tablets to see that they meet our standards for consistency in size, color, aroma or taste, are not broken, and contain no contaminants. Representative samples are taken to verify potency. Tablets and capsules are tested to ensure they are consistent in size and comply with USP standards for weight variation. Threshold utilizes USP disintegration standards* as its guidelines to ensure tablets will break up appropriately after ingestion, making the ingredients available for use by your body.

*Under USP 25 standard conditions: Coated tablets: 50 minutes in water. Capsules: 45 minutes in buffered acetate or water.

Rigorous Laboratory Procedures

Methods used include: HPLC (High Performance Liquid Chromatography), IR (Fourier Transform Infrared), UV/Vis Spectrophotometry, Graphite Furnace Atomic Absorbance Spectroscopy, TLC (Thin Layer Chromatography), Microbiology testing, and organoleptic inspection including visual, color, odor, clarity, pH, and taste.

Raw materials must comply with vendor Certificates of Analysis as well as with our rigorous specifications.

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MSM - Natures Primary Sources of Organic Dietary Sulfur
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Date: August 02, 2005 03:48 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: MSM - Natures Primary Sources of Organic Dietary Sulfur


Best MSM    

The MSM Story-One of Nature's Primary Sources
of Organic Dietary Sulfur! The human body requires a continuous
supply of usable sulfur, and MSM is one of the primary organic
sulfur-containing molecules for use by living organisms. From
life's earliest beginnings, primitive marine organisms
(blue-green algae and phytoplankton) have absorbed inorganic
sulfur from ocean waters and produced organic sulfur molecules,
primarily dimethyl sulfonium salts. These salts are released
back into the sea, where they are converted to dimethyl sulfide,
which readily evaporates, ending up in the upper atmosphere.
Dimethyl sulfide is then oxidized by UV light, forming DMSO and
MSM. The two compounds are delivered to land masses in rain
water, and absorbed by plants. MSM is a stable end-product of
this process, and thus serves as a primary source of sulfur in
the food chain.

Though present on earth since before life
appeared on dry land, and known to science since the 1950's, MSM
has only recently been recognized as having importance in human
nutrition.

Why the Human Body Needs MSM MSM occurs naturally
in the blood, body fluids and tissues. It is now believed that a
minimum MSM concentration of 0.2 parts per million is necessary
for the body to function normally. MSM may be the most easily
absorbed and non-toxic source of nutritional sulfur occurring in
nature.

Sulfur is a structural mineral that maintains the
strength of various tissues by forming sulfur "tie-bars"
(sulfhydryl bonds) between connective tissue proteins. MSM
serves as a readily available source of sulfur for this
function, and thus helps maintain the pliancy of tissues and
cell membranes. Repair of damaged tissue depends upon a supply
of sulfur for continuation of reactions involving sulfhydryl
groups (-SH). Sulfur is required for the maintenance of healthy
hair, skin and nails. In view of the presence of MSM in
biological systems since the beginning of evolution, it is
logical to assume that all higher life forms, including humans
and animals, are well adapted to use MSM as a sulfur
donor.

MSM Benefits Clinical research on the role of MSM in
the human body has culminated in the filing of several patents
covering numerous uses for MSM as a dietary ingredient for both
humans and animals. As a result of these investigations, it is
believed that physical and psychological stress increases in the
human body when the MSM concentration falls below minimum
levels, resulting in a loss of normal organ function.

Based
on observations, ingestion of MSM by humans has the following
beneficial effects:

• MSM supports maintenance of strong,
healthy body tissues by donating sulfur for formation of sulfur
tie-bars between connective tissue proteins.*

• MSM supports
normal gastrointestinal function.*

• MSM improves the body's
resistance to adverse physical stress.*

• MSM supports mental
alertness and maintenance of healthy mood.*

• MSM promotes the
body's processes that heal tissue.*

• MSM helps modify the
physiologic response to allergens.*

• MSM supports normal lung
function.*

• MSM supports normal relaxation of muscles.*

• MSM
supports normal joint function.*

• MSM helps maintain healthy
skin.*

Supplementation is Needed to Realize the Benefits of
MSM Widespread in nature, MSM is found in a variety of foods,
including fresh fruits and vegetables, raw milk, raw meat and
raw fish. However, MSM is a volatile substance easily lost
during cooking, pasteurization, food processing and storage. The
average American diet thus supplies at best a marginal MSM
intake, which may be inadequate to maintain the optimum MSM
concentration in the body. The body's MSM concentration is also
believed to decline with increasing age.

Dosage
Recommendations Effective dosages for the various reported uses
of MSM range from 500 mg to 6 grams per day. 1000 mg per day is
recommended to restore normal MSM concentrations, while higher
doses may be necessary for specific uses.

MSM is considered
to be as non-toxic to the body as water, and is therefore
completely safe at the higher dosage levels.

*These
statements have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat,
cure, or prevent any disease.

Scientific Abstracts and
References

1. Jacob, S., Herschler, R. Introductory remarks:
dimethyl sulfoxide after 20 years. Annals of the New York
Academy of Sciences 1983; 411:xiii-xvii.

2. Herschler, R.
Dietary and pharmaceutical uses of methylsulfonylmethane and
compositions comprising it. United States Patent 4,514,421;
April 30, 1985.

3. Herschler, R. Methylsulfonylmethane in
dietary products. United States Patent 4,616,039; October 7,
1986.

4. Sellnow, L. MSM: An Aid From Nature. The Blood Horse,
June 6, 1987:3459-3462.

5. Lawrence, R.M.
Methyl-sulfonylmethane (M.S.M.) A double-blind study of its use
in degenerative arthritis.

International Journal of Anti-Aging
Medicine 1998;1(1):50 6. Jacob, S.W., Lawrence, R.M., Zucker,
M. 1999. The Miracle of MSM. New York: G.P. Putnam's Sons.



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THE FDA AND STEVIA
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Date: July 15, 2005 12:45 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: THE FDA AND STEVIA

THE FDA AND STEVIA

While stevia in no way qualifies as an “artificial sweetener,” it has been subject to rigorous inquiry and unprecedented restraints. In 1986, FDA officials began to investigate herb companies selling stevia and suddenly banned its sale, calling it “an unapproved food additive.” Then in 1991, the FDA unexpectedly announced that all importation of stevia leaves and products must cease, with the exception of certain liquid extracts which are designed for skin care only. They also issued formal warnings to companies and claimed that the herb was illegal. The FDA was unusually aggressive in its goal to eliminate stevia from American markets, utilizing search and seizure tactics, embargoes and import bans. Speculation as to why the FDA intervened in stevia commerce points to the politics of influential sugar marketers and the artificial-sweetener industry.

During the same year, the American Herbal Products Association (AHPA) began their defense of the herb with the goal of convincing the FDA that stevia is completely safe. They gathered documented literature and research on both stevia and other non-caloric sweeteners. The overwhelming consensus was that stevia is indeed safe, and the AHPA petitioned the FDA to exempt stevia from food additive regulations.

Food Additive vs. Dietary Supplement

FDA regulations of stevia were based on its designation as a food additive. The claim was that scientific study on stevia as a food additive was inadequate. Ironically, extensive Japanese testing of stevia was disregarde—regardless of the fact that this body of documented evidence more than sufficiently supported its safe use. Many experts who have studied stevia and its FDA requirements have commented that the FDA wants far more proof that stevia is safe than they would demand from chemical additives like aspartame.

Stevia advocates point out that stevia not a food additive, but rather, a food. Apparently, foods that have traditionally been consumed do not require laborious and expensive testing for safety under FDA regulations. The fact that so many toxicology studies have been conducted in Japan, coupled with the herb’s long history of safe consumption, makes a strong case for stevia being accepted by the FDA as a safe dietary substance. Still, it was denied the official GRAS (generally recognized as safe) status and designated a food additive by the FDA.

The FDA Reverses Its Position

As a result of the Health Freedom Act passed in September of 1995, stevia leaves, stevia extract, and stevioside can be imported to the United States. However, ingredient labels of products that contain stevia must qualify as dietary supplements.

Stevia had been redesignated as a dietary supplement by the FDA and consequently can be legally sold in the United States solely as a supplement. Its addition to teas or other packaged foods is still banned. Moreover, stevia cannot, under any circumstances, be marketed as a sweetener or flavor enhancer.

SUGAR, SUGAR EVERYWHERE

Ralph Nader once said, “If God meant us to eat sugar, he wouldn’t have invented dentists.” The average American eats over 125 pounds of white sugar every year. It has been estimated that sugar makes up 25 percent of our daily caloric intake, with soda pop supplying the majority of our sugar ingestion. Desserts and sugar-laden snacks continually tempt us, resulting in an escalated taste for sweets.

The amount of sugar we consume has a profound effect on both our physical and mental well-being. Sugar is a powerful substance which can have drug-like effects and is considered addictive by some nutritional experts. William Duffy, the author of Sugar Blues, states,“The difference between sugar addiction and narcotic addition is largely one of degree.” In excess, sugar can be toxic. Sufficient amounts of B-vitamins are actually required to metabolize and detoxify sugar in our bodies. When the body experiences a sugar overload, the assimilation of nutrients from other foods can be inhibited. In other words, our bodies were not designed to cope with the enormous quantity of sugar we routinely ingest. Eating too much sugar can generate a type of nutrient malnutrition, not to mention its contribution to obesity, diabetes, hyperactivity, and other disorders. Sugar can also predispose the body to yeast infections, aggravate some types of arthritis and asthma, cause tooth decay, and may even elevate our blood lipid levels. Eating excess sugar can also contribute to amino acid depletion, which has been linked with depression and other mood disorders. To make matters worse, eating too much sugar can actually compromise our immune systems by lowering white blood cells counts. This makes us more susceptible to colds and other infections. Sugar consumption has also been linked to PMS, osteoporosis and coronary heart disease.

Why Do We Crave Sweets?

Considering the sobering effects of a high sugar diet, why do we eat so much of it? One reason is that sugar gives us a quick infusion of energy. It can also help to raise the level of certain brain neurotransmitters which may temporarily elevate our mood. Sugar cravings stem from a complex mix of physiological and psychological components. Even the most brilliant scientists fail to totally comprehend this intriguing chemical dependence which, for the most part, hurts our overall health.

What we do know is that when sugary foods are consumed, the pancreas must secrete insulin, a hormone which serves to bring blood glucose levels down. This allows sugar to enter our cells where it is either burned off or stored. The constant ups and downs of blood sugar levels can become exaggerated in some individuals and cause all kinds of health problems. Have you ever been around someone who is prone to sudden mood swings characterized by violent verbal attacks or irritability? This type of volatile behavior is typical of people who crave sugar, eat it and then experience sugar highs and lows. Erratic mood swings can be linked to dramatic drops in blood sugar levels.

Hypoglycemia: Sign of Hard Times?

It is rather disturbing to learn that statisticians estimate that almost 20 million Americans suffer from some type of faulty glucose tolerance. Hypoglycemia and diabetes are the two major forms of blood sugar disorders and can deservedly be called modern day plagues. Hypoglycemia is an actual disorder that can cause of number of seemingly unrelated symptoms. More and more studies are pointing to physiological as well as psychological disorders linked to disturbed glucose utilization in brain cells. One study, in particular, showed that depressed people have overall lower glucose metabolism (Slagle, 22). Hypoglycemia occurs when too much insulin is secreted in order to compensate for high blood sugar levels resulting from eating sugary or high carbohydrate foods. To deal with the excess insulin, glucagon, cortisol and adrenalin pour into the system to help raise the blood sugar back to acceptable levels. This can inadvertently result in the secretion of more insulin and the vicious cycle repeats itself.

A hypoglycemic reaction can cause mood swings, fatigue, drowsiness, tremors, headaches, dizziness, panic attacks, indigestion, cold sweats, and fainting. When blood sugar drops too low, an overwhelming craving for carbohydrates results. To satisfy the craving and compensate for feelings of weakness and abnormal hunger, sugary foods are once again consumed in excess.

Unfortunately, great numbers of people suffer from hypoglycemic symptoms. Ironically, a simple switch from a high sugar diet to one that emphasizes protein can help. In addition, because sugar cravings are so hard to control, a product like stevia can be of enormous value in preventing roller coaster blood sugar levels. One Colorado internist states: People who are chronically stressed and are on a roller coaster of blood sugar going up and down are especially prone to dips in energy at certain times of day. Their adrenals are not functioning optimally, and when they hit a real low point, they want sugar. It usually happens in mid-afternoon when the adrenal glands are at their lowest level of functioning. (Janiger, 71) Our craving for sweets in not intrinsically a bad thing; however, what we reach for to satisfy that craving can dramatically determine how we feel. Stevia can help to satisfy the urge to eat something sweet without changing blood sugar levels in a perfectly natural way and without any of the risks associated with other non-nutritive sweeteners.

Diabetes: Pancreas Overload?

Diabetes is a disease typical of western cultures and is evidence of the influence that diet has on the human body. Perhaps more than any other disease, diabetes shuts down the mechanisms which permit proper carbohydrate/sugar metabolism. When the pancreas no longer secretes adequate amounts of insulin to metabolize sugar, that sugar continues to circulate in the bloodstream causing all kinds of health problems. The type of diabetes that comes in later years is almost always related to obesity and involves the inability of sugar to enter cells, even when insulin is present. Diabetes can cause blindness, atherosclerosis, kidney disease, the loss of nerve function, recurring infections, and the inability to heal. Heredity plays a profound role in the incidence of diabetes, but a diet high in white sugar and empty carbohydrates unquestionably contributes to the onset of the disease. It is estimated that over five million Americans are currently undergoing medical treatment for diabetes and studies suggest that there are at least four million Americans with undetected forms of adult onset diabetes. Diabetes is the third cause of death in this country and reflects the devastating results of a diet low in fiber and high in simple carbohydrates. Most of us start our children on diets filled with candy, pop, chips, cookies, doughnuts, sugary juice, etc. Studies have found that diabetes is a disease which usually plagues societies that eat highly refined foods. Because we live in a culture that worships sweets, the availability of a safe sweetener like stevia, which does not cause stress on the pancreas is extremely valuable. If sugar consumption was cut in half by using stevia to

  • “stretch”
  • sweetening power, our risk for developing blood sugar disorders like diabetes and hypoglycemia could dramatically decrease.

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    THE FDA AND NON-CALORIC SWEETENERS
    TopPreviousNext

    Date: July 15, 2005 12:27 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: THE FDA AND NON-CALORIC SWEETENERS

    THE FDA AND NON-CALORIC SWEETENERS

    While white sugar, turbinado, fructose, honey and corn syrup all qualify as natural sweeteners, none of these are calorie- free nor can they be used by people who suffer from blood sugar disorders. They can encourage weight gain, tooth decay, raise blood sugar quickly, and can also predispose certain individuals to yeast infections. These sugars can also contribute to indigestion, bowel disorders and, possibly, hyperactivity or ADD in children. Pharmaceutical sweeteners like aspartame and saccharin qualify as calorie-free but come with significant limitations and health risks. Saccharin has been labeled with a warning that it has caused the development of cancer in laboratory animals but is still available for purchase. In 1970, cyclamates, another class of artificial sweeteners, were banned because of the strong possibility that they are, in fact, carcinogenic. Aspartame has been marketed as a safe substance for the general public, except for those few individuals who suffer from PKU (phenylketonuria), a relatively rare disorder. Most consumers assume that aspartame is a perfectly benign compound and use it liberally. It is, in fact, comprised of phenylalanine, aspartic acid, and methanol (wood alcohol). As previously mentioned, various side effects have been associated with the ingestion of aspartame and include migraines, memory loss, slurred speech, dizziness, stomach pain, and even seizures.

    In addition, because aspartame contains chemicals which affect brain cell function, significant questions have been raised concerning its link to increased incidence of brain tumors (Olney). Acesulfame K, another artificial sweetener on the market, has also been linked to cancer by the Center for Science in the Public Interest. Despite the protest of various organizations and health professionals, these pharmaceutical s weeteners have been approved by the FDA and are recognized as safe.

    (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=641)


    HOW BIOAVAILABLE IS PYCNOGENOL?
    TopPreviousNext

    Date: July 13, 2005 12:30 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: HOW BIOAVAILABLE IS PYCNOGENOL?

    HOW BIOAVAILABLE IS PYCNOGENOL?

    The results of isotopic testing confirmed that grape seed proanthocyanidins had a specific affinity for collagen, and demonstrated how long the bioflavonoid complex adhered to living tissue. Because this testing was not possible on pine bark sources of proanthocyanidins, data collected from grape seed testing has been extrapolated or applied to pine bark. Pycnogenol is rapidly absorbed and transported throughout the cellular system due to the high water solubility of the proanthocyanidins. Within one hour of ingesting this bioflavonoid complex, proanthocyanidins can be detectedin human saliva. Pycnogenol uptake in the body is rapid and is quickly distributed.

    The bot tom line is that Pycnogenol is a water-soluble bioflavonoid which is quickly assimilated after ingestion into the bloodstream. There, it acts to scavenge free radicals and to strengthen connective tissue. The proanthocyanidins found in Pycnogenol can not only scavenge and remove free radicals, but inhibit their propagation as well.

    THE TOLERABILITY AND SAFETY OF PYCNOGENOL

    It would certainly be pointless to find a substance that while seemingly beneficial, was not safe or could not be well tolerated by its users. Studies have shown that pure sources of Pycnogenol are practically devoid of any oral toxicity. Even extremely high dosages administered over sustained periods of time showed no toxicity or side-effects.14 Virtually no actual or potential risks were found with this compound. Pycnogenol has been shown to be safe for conception, pregnant women, and the unborn fetus. It is devoid of any perior postnatal toxicity. On the contrary, the compounds were found to not only benefit targeted disorders, but a variety of other conditions improved as well.

    (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=609)


    SILYMARIN: LITTLE KNOWN ANTIOXIDANT
    TopPreviousNext

    Date: July 12, 2005 10:02 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: SILYMARIN: LITTLE KNOWN ANTIOXIDANT

    SILYMARIN: LITTLE KNOWN ANTIOXIDANT

    The antioxidant bioactivity of the silymarin compounds contained in Milk Thistle have been generally overlooked by experts who suggest taking vitamin E, C, A, beta - carotene and selenium supplements. Adding Milk Thistle to this complement of antioxidants is strongly recommended, especially for anyone who smokes, consumes alcohol or must take drugs on a continual basis. The hepato-protective properties of silymarin combined with its free scavenging action make it an invaluable defense against so many toxins which pollute our bodies. Studies suggest that taking Milk Thistle on a daily basis may provide the liver with protection against heavy metals, environmental pollutants and dietary toxins. One study confirmed that Silymarin did indeed neutralize the damaging effects of cadmium, which can accumulate in living tissue.11

    The implications of clinical trials on Milk Thistle suggest that regular ingestion of silymarin can provide a significant amount of free radical protection during the course of one's inevitable encounter with air, water or food born pollutants.12

    The protective potential of Milk Thistle has only just begun to be investigated. If it can perform so admirably against potent poisons, it most likely has a whole host of other protective actions. As an antioxidant, it should be added to the typical list of supplements we need to take for cellular defense.

    (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=585)


    HAWAIIAN NONI (Morinda citrifolia)
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    Date: July 11, 2005 08:50 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: HAWAIIAN NONI (Morinda citrifolia)

    INTRODUCTION

    In a time when we are more concerned than ever with issues of health, a tried and true tropical herb called noni needs t o be added t o our list of the best natural remedies. It susage over hundreds of years supports it s description as a veritable panacea of therapeutic actions. At this writing, noni continues to accrue impressive medicinal credentials, and its emergence as an effective nat ural healing agent is a timely one. Amidst rising cancer rates, the high incidence of degenerative diseases like diabetes, and the evolution of ant ibiotic resist ant bacteria and new viral strains, herbs like noni are sought after for their natural pharmaceutical properties. Unquest ionably, all of us want to know how to:

  • • protect ourselves f rom toxins and pollut ants
  • • prevent t he premature onset of age-related diseases such as arthritis, heart disease, diabetes and stroke
  • • boost our immune defenses to protect ourselves from new viral and bacterial strains that have become antibiotic-resist ant
  • • reduce our risk of developing cancer
  • • better digest our food for proper assimilation and purge the intestinal system wit hout the dangerous side effects of harsh drugs. Its actions are multifaceted and must be considered when assessing natural treatment s for disease or injury. It s impressive and widespread use among various native cult ures of t ropical island regions supports the notion that it does indeed possess valuable, therapeutic compounds.

    Genus Rubiaceae

    Common Names

    Indian Mulberry (India), Noni (Hawaii), Nono (Tahiti and Raratonga), Polynesian Bush Fruit, Painkiller Tree (Caribbean islands), Lada (Guam), Mengkudo (Malaysia), Nhau (Southeast Asia), Grand Morinda (Vietnam), Cheesefruit (Australia), Kura (Fiji), Bumbo (Africa) Note: This is only a small sampling of vernacular names for Morinda citrifolia. Almost every island nation of the South Pacific and Caribbean has a term for this particular plant . This booklet will refer to the herb mainly as “ noni” or M. citrifolia, and is referring primarily to Hawaiin noni.

    Parts Used

    The parts of the noni plant most used for their medicinal and nutritional purposes are the fruit, seeds, bark, leaves, and flowers. Virtually every part of the noni plant is utilized for its individual medicinal properties; however, it is the fruit portion that is regarded as its most valuable. The seeds have a purgative action, the leaves are used to treat external inflammations and relieve pain, the bark has strong astringent properties and can treat malaria, the root extracts lower blood pressure, the flower essences relieve eye inflammations and the f ruit has a number of medicinal actions.

    Physical Description

    Morinda citrifolia is technically an evergreen shrub or bush, which can grow to heights of fifteen to twenty feet . It has rigid, coarse branches which bear dark, oval, glossy leaves. Small white fragrant flowers bloom out of cluster-like pods which bear creamy-white colored fruit. The fruit is fleshy and gel-like when ripened, resembling a small breadf ruit . The flesh of the fruit is characterist ically bitter, and when completely ripe produces a rancid and very dist inctive odor. Noni has buoyant seeds that can float formont hs in ocean bodies. The wood of the inflammatory, astringent, emollient, emmenagogue, laxative, sedative, hypotensive (lowers blood pressure) , blood purif ier, and tonic.

    Chemical Constituents

    Noni has various chemical constituents. First, it has an impressive array of terpene compounds, three of which—L. Asperuloside, aucubin, and glucose— have been identified by their actyl derivatives. Both caproic and caprylic acids have been isolated.1 Second, bushfruits, a category of which noni fruit is a member, are also considered a good source of vit - amin C.2 Third, Hawaiin noni has been linked to the synthesis of xeronine in the body which has significant and widespread health implications. Last , the alkaloid cont ent of the noni fruit is thought to be responsible for its therapeutic actions. Alkaloids exhibit a wide range of pharmacological and biological act ivitiesin the human body. They are nitrogencontaining organic compounds which can react with acids to form salts and which are the basis of many medicines. The following is an in-depth chemical analysis of each plant part and it s chemical constituents.

  • • amino acids (which include alanine, arginine, asparticacids, cysteine, cystine, glycine, glutamic acid, histidine, leucine, isoleucine, methionine, phenylalanine, proline, serine, threonine, tryptophan tyrosine, and valine)
  • • anthraquinones
  • • glycosides
  • • phenolic compounds
  • • resins
  • • B-sitosterol
  • • ursolic acid

    FLOWER

  • • acacet in 7-0-D (+) -glucophyranoside
  • • 5,7,-dimet hylapigenin-4-0-8-D(+) -galactophyranoside
  • • 6,8,-dimet hoxy-3-methyl anthroquinone-1-0-8-rhamnosyl glucophyranoside

    FRUIT

  • • antioxidant
  • • alizarin
  • • anthraquinones
  • • caproic and caprylic acids

    discovered an alkaloid in the Hawaiin noni fruit which he calls proxeronine and which he believes has appreciable physiological actions by acting as a precursor to xeronine, a very crucial compound (see later sections) . In addition, a compound found in the fruit called damnacanthol is believed to help inhibit cert ain viruses and cellular mutations involved in cancer.

    ROOT AND ROOT BARK

  • • carbonate
  • • chlorubin
  • • rubicholric acid
  • • soranjidol
  • • chrysophanol
  • • phosphate
  • • magnesium
  • • ferric iron
  • • sodium
  • • glycosides
  • • morinadadiol
  • • morindine
  • • resins
  • • rubiadin
  • • sterols4

    Pharmacology

    Recent surveys have suggested that noni fruit exerts antibiotic action. In fact, a variety of compounds which have antibacterial properties (such as aucubin) have been identified in the fruit.5 The 6-Dglucopyranose pentaacet ate of the fruit extract is not considered bacteriostatic.6 Constituents found in the fruit portion have exhibited ant imicrobial action against Escherichia coli, Salmonella typhi (and other types) , Shigella paradysenteriae, and Staphylococcus aureaus. Compounds found in the root have the ability to reduce swollen mucous membrane and lower blood pressure in animal studies. Proxeronine is an alkaloid constituent found in Hawaiin noni fruit which may prompt the production of xeronine in the body. It is considered a xeronine precursor and was discovered in noni fruit by Dr. Ralph M. Heinicke. He has theorized that this proenzyme can be effective in initiating a series of beneficial cellular reactions through its involvement with the integrity of specific proteins. He points out that tissues contain cells which possess certain recept or sites for xeronine. Because the reactions that can occur are so varied, many different therapeutic actions can result when xeronine production escalates, explaining why Hawaiin noni is good for so many seemingly unrelated disorders. Damnacanthol is another compound contained in the fruit of the Hawaiin noni plant which has shown the ability to block or inhibit the cellular function of RAS cells, considered pre-cancerous cells.

    Body Systems Targeted

    The following body systems have all been effec-freeze-dried capsules, dehydrated powder or fruit, and oil. Noni plant constituents are sometimes offered in combination with other herbs. Some products contain a percent age of the fruit, bark, root and seeds for their individual therapeutic properties.

    Satety

    Extracts of M. citrifolia are considered safe if used as directed; however, pregnant or nursing mothers should consult their physicians before taking any supplement . High doses of root extracts may cause constipation. Taking noni supplements with coffee, alcohol or nicotine is not recommended.

    Suggested Uses

    Ideally, noni extracts should be taken on an empty stomach prior to meals. The process of digesting food can interfere with the medicinal value of the alkaloid compounds found in Hawaiin noni, especially in its fruit . Apparently, stomach acids and enzymes destroy the specific enzyme which frees up the xeronine compound. Take noni supplements without food, coffee, nicotine or alcohol. Using supplements that have been made from the semi-ripe or light - green fruit is also considered preferable to the ripe, whit ish fruit .

    NONI: ITS USE AND HISTORY

    Noni is a tropical wandering plant indigenous to areas of Australia, Malaysia and Polynesia. It is considered native to Southeast Asia although it grows from India to the eastern region of Polynesia. Morinda citrifolia has a long history of medicinal use throughout these areas. It is thought to be the “most widely and commonly used medicinal plant prior to the European era.” 7 Centuries ago, the bushfruit was introduced to native Hawaiians, who subsequently called it “noni” and considered its fruit and root as prized medicinal agents. Among all Polynesian botanical agents of the 19th and 20th centuries, Hawaiin noni has the widest array of medical applications. Samoan and Hawaiian medical practitioners used noni for bowel disorders (especially infant diarrhea, constipation, or intestinal parasites) , indigestion, skin inflammation, infection, mouth sores, fever, contusions and sprains. Hawaiians commonly prepared noni tonics designed to treat diabetes, stings, burns and fish poisoning.8 The herb’s remarkable ability to purge the intestinal tract and promote colon health was well known among older Hawaiian and Tahitian natives and folk healers. Interestingly, field observations regarding its repu-remarkable healing agent .

    Wonder Herb of Island Folk Healers

    Common to t he thickets and forests of Malaysia and Polynesia, and the low hilly regions of the Philippine islands, noni has been cultivated throughout communities in the South Pacific for hundreds of years. Its Hawaiian use is thought to originate from inter-island canoe travel and settlement dating to before Christ . Its hardy seeds have the ability to float which has also contributed to its distribution among various seacoasts in the South Pacific region. Historical investigation has established the fact that some of Hawaii’s earliest settlers probably came viaTahiti. For this reason, Tahitian herbal practices have specific bearing on the herbal therapeutics of islands to the nort h. The very obvious similarities between the Hawaiian vernacular for herbal plants like noni and Tahitian names strongly suggests the theory of Polynesian migrations to Hawaii. Cultures native to these regions favored using Morinda citrifolia for treating major diseases and ut ilized it as a source of nourishment in times of famine.9 Noni fruit has been recognized for centuries as an excellent source of nutrition. The peoples of Fiji, Samoa and Rarat onga use the fruit in both its raw and cooked forms.10 Traditionally, the fruit was propicked before it was fully ripe and placed in the sunlight . After being allowed to ripen, it was typically mashed and its juice extracted through a cloth. Noni leaves provided a veget able dish and their resiliency made them desirable as a fish wrap for cooking.

    Noni’s Medical Reputation

    Elaborate traditionalrituals and praying rites usually accompanied the administration of noni. Int erestingly, cultures indigenous to the Polynesian islands had a significant understanding of their flora. For example, native Hawaiians maint ained a folkmedicine taxonomy t hat was considered second to none.11 Noni was not only used for medicinal purposes but for its food value, for clot hing and for cloth dyes as well. Research indicates that noni was among the few herbal remedies that islanders considered “ tried and true.” In Hawaii, trained herbal practitioners reserved the right to prescribe plant therapies.12 Records indicate that Hawaiian medical practices were based on extensive and very meticulous descriptions of symptoms and their prescribed herbal treatments. Dosages were controlled and the collection and administration of plant extracts was carefully monitored.13 In addition to Morinda, it was not uncommon for these herbal doctors to also recommend using In regard to its application for common ailments, Hawaiians and other island communities traditionally prescribed noni to purge the bowel, reduce fever, cure respiratory infections such as asthma, ease skin inflammations, and heal bruises and sprains. In other words, noni was widely used and highly regarded as a botanical medicine.

    A Timely Reemer gence

    Today, the natural pharmaceutical actions of the chemical constituents contained in noni are scientif-ically emerging as valuable bot anical medicines. Tahitian “nono” intrigued medical practitioners decades ago; however, due to the eventual emergence of synthetic drugs, interest in this island botanical diminished until recent years. Ethnobot anists are once again rediscovering why Hawaiian people havet reasured and cultivat ed Morinda citrifolia for generations. Noni is now finding its way into western therapeutics and is referred to as “ the queen” of the genus Rubiaceae. Its ability to reduce joint inflammation and target the immune system have made it the focus of the modern scientific inquiry. Dr. Ralph Heinicke has conducted some fascinating studies on the chemical constituents of the Hawaiin noni fruit. His research centers on the proxeronine content of the fruit juice and how it profoundly influences human physiology. In addition, scientific studies investigating noni as an anti-cancer agent have been encouraging. It s conspicuous attributes and varied uses have elevat edits status to one of the best of the healing herbs. Today Morinda citrifolia is available in liquid, juice, freezedried capsules, or oil forms, and is considered one of nature’s most precious botanicals.

    TRADITIONAL USES OF NONI

    Throughout tropical regions, virtually every part of Morinda citrifolia was used to treat disease or injury. Its curative properties were well known and commonly employed. PatoaTama Benioni, a member of the Maoritribe from the Cook Islands and a lecturer on island plants explains: Traditionally Polynesians use noni for basically everything in the treatment of illness. Noni is a part of our lives. Any Polynesian boy will tell you he’s had exper ience with it . We use juice from its roots, its flowers, and its fruit... my grandmother taught me to use noni from the roots and the leaves to make medicine for external as well as internal use, and for all kinds of ailments, such as coughs, boils, diseases of the skin, and cuts.15

    decoctions to stimulate delayed menst ruation.

  • • Noni was frequently utilized for its antiparasitic activity.
  • • Respiratory ailments, coughs, and colds were treated with noni.
  • • A juice made from pounding noni leaves, roots and fruit mixed with water was administered for diarrhea.
  • • Dried and powdered forms of the bark mixed with water and administ ered with a spoon treated infant diarrhea.
  • • Small pieces of fruit and root infused with water were given to kill intestinal parasites.
  • • Boiled bark decoctions were given as a drink for stomach ailments.
  • • Coughs were treated with grated bark.
  • • Charred unripe fruit was used with salt on diseased gums.
  • • Pounded fruit combined with kava and sugar cane was used to treat tuberculosis.
  • • Babies were rubbed with fresh, crushed leaves for serious chest colds accompanied by fever.
  • • Eye washes were made from decoctions for eye complaint s from flower extracts.
  • • Leaf infusions were traditionally taken to treat adult fevers.
  • • A mouthwash consisting of crushed ripe fruit and juice was used for inflamed gums in young boys.
  • • Pounded leaf juice was used for adult gingivitis.
  • • Sore throats were treated by chewing the leaves and swallowing the juice.
  • • Skin abscesses and boils were covered with leaf poultices.
  • • Swelling was controlled with leaf macerations.
  • • Heated leaves were often used for arthritic joins and for ringworm.16

    XERONINE: THE SECRET OF NONI?

    One informed professional on the subject of noni is Dr. Ralph Heinicke, a biochemist who has researched the active compounds of noni fruit for a number of years. He discovered that the Hawaiin noni fruit contains an alkaloid precursor to a very vital compound called xeronine. Wit hout xeronine, life would cease. In Dr. Heinicke’s view, noni fruit provides a safe and effective way to increase xeronine levels, which exert a crucial influence on cell health and protction. His research suggests that the juice from the M. citrifolia fruit contains what could technically be considered a precursor of xeronine—proxeronine. This compound initiates the release of xeronine in the intestinal tract after it comes in contact with a specific enzyme which is also contained in the fruit .

    Because proteins and enzymes have so many varied roles within cell processes, the normalization of these proteins with noni supplemenation could initiate avery wide variety of body responses and treat many disease condit ions. Proteins are the most important catalysts found in the body. The beauty of obtaining a precursor to xeronine from the noni fruit is that the body naturally decides how much of this precursor to convert to xeronine. Disease, stress, anger, trauma and injury can lower xeronine levels in the body, thus creat ing a xeronine deficit . Supplementing the body with noni fruit is considered an excellent way to safely and naturally raise xeronine levels. It is the research and theories of Dr. Heinicke which have made the juice of the Hawaiin noni fruit a viable medicinal substance. He writes: Xeronine is analkaloid, a substance the body produces in order to activate enzymes so they can function properly. It also energizes and regulates the body. This par-ticular alkaloid has never been found because the body makes it, immediately uses it, and then breaks it down. At no time is there an appreciable, isolable amount in the blood. But xeronine is so basic to the functioning of proteins, we would die without it . Its absence can cause many kinds of illness.17 Because so many diseases result from an enzyme malfunction, Dr. Heinicke believes that using the noni fruit can result in an impressive array of curative applications. Interestingly, he believes that we manufacture proxeronine while we are sleeping. He proposes t hat if we could constantly supply our bodies wit h proxeronine from other sources, our need to sleep would diminish.18

    NONI PROCESSING

    How an herb is processed is crucial to how beneficial it is: this is especially true of noni, with its unique enzymes and alkaloids. Morinda citrifolia should be picked when the fruit is turning from its dark green immature color to its lighter green color, and certainly before it ripens to its white, almost translucent color. Once picked, noni, like aloe, will denature extremely quickly due to its very active enzymes. After harvesting, it should swiftly be flash frozen. This is similar to what is done to fish caught at sea to keep them f esh. This stops it from losing its potency while not damaging any of its constituents. To process noni, freeze-drying is recommended. This removes only the water without damaging any of this miracle plant’s vital enzymes and other phytonutrients like xeronine and proxeronine. This pure high-quality noni fruit juice powder is then encapsu-has a very harsh taste and an extremely foul smell, similar to the fruit it self . Other methods of processing include thermal processing, dehydrat ion and air drying. Thermal processing is generally found in liquids, while the dehydrat ed noni is then milled and encapsulated. Unfortunately both methods utilize high heat (110+°F) , which can deactivate many of the vital compounds that make noni so import ant . Air-drying is effect ive without using damaging heat but has serious quality control problems for commercial production.

    MODERN APPLICATIONS OF NONI

    Overview

    Noni possesses a wide variety of medicinal properties which originat e from its differing plant component s. The fruit and leaves of the shrub exert antibacterial activities. Its roots promote the expulsion of mucus and the shrinkage of swollen membranes making it an ideal therapeutic for nasal congest ion, lung infect ions, and hemorrhoids. Noni root compounds have also shown natural sedative properties as well as the ability to lower blood pressure.

    Leaf extracts are able to inhibit excessive blood flow or to inhibit the formation of blood clots. Noni is particularly useful for its ability to treat painful joint conditions and to resolve skin inflammations. Many people drink noni fruit extracts in juice form for hypert ension, painful menstruation, arthritis, gastric ulcers, diabetes, and depression. Recent studies suggest that its anticancer activit y should also be considered. Concerning the therapeutic potential of the Hawaiin noni fruit, Dr. Heinicke writes: I have seen the compound found in noni work wonders. When I was still investigating its possibilities, I had a friend who was a medical research scientist administer the proxeronine to a woman who had been comatose for three months. Two hour safter receiving the compound, she sat up in bed and asked where she was. . . . Noni is probably the best source of proxeronine that we have today.19 Studies and surveys combined support the ability of noni to act as an immunost imulant, inhibit the growth of certain tumors, enhance and normalize cellular function and boost tissue regeneration. It is considered a powerful blood purifier and contributor to overall homeostasis.

    xeronine, which appears to be able to regulate the shape and integrity of cert in proteins that individually contribute to specific cellular activities. Interestingly, this effect seems to occur after ingestion, inferring that the most active compound of noni may not be present in uneaten forms of the fruit or other plant parts. Some practitioners believe that xeronine is best obtained from a noni fruit juice precursor compound. The enzymatic reactions that occur with taking the juice on an empty stomach are what Dr. Heinicke believes set cellular repair intomotion.

    Cancer

    A study conducted in 1994 cited the anticancer activity of Morinda citrifolia against lung cancer. A team of scientists from the University of Hawaii used live laboratory mice to test the medicinal properties of the fruit against Lewis lung carcinomas which were artificially transferred to lung tissue. The mice that were left untreated died in nine to twelve days. However, giving noni juice in consistent daily doses significantly prolonged their life span. Almost half of these mice lived for more than fifty days.20 Research conclusions state that the chemical constituents of the juice acted indirectly by enhancing the ability of the immune system to deal with the invading malig-nancy by boosting macrophage or lymphocyte activit y. Furt her evaluation theorizes that the unique chemical constituents of Morinda citrifolia initiate enhanced T-cell activity, a reaction that may explain noni’s ability to treat a variety of infectious diseases. 21

    In Japan, similar studies on tropical plant extracts found that damnacanthol, a compound found in Morinda citrifolia, is able to inhibit the function of KRAS- NRK cells, which are considered precursors to certain types of malignancies.22 The experiment involved adding noni plant extract to RAS cells and incubating them for a number of days. Observation disclosed that noni was able to significantly inhibit RAS cellular function. Among 500 plant extracts, Morinda citrifolia was determined to contain the most effective compounds against RAS cells. Its damnacanthol content was clinically described in 1993 as “a new inhibit or of RAS function.” 2 3 The xeronine fact or is also involved in that xeronine helps to normalize the way malignant cells behave. While they are still technically cancer cells, they no longer function as cells with unchecked growth. In time, the body’s immune system may be able to eradicate these cells.

    Arthritis

    with arthritic disease. One link to arthritic pain may be the inability to properly or completely digest proteins which can then form crystal-like deposits in the joints. The ability of noni fruit to enhance protein digestion through enhanced enzymatic function may help to eliminate this particular phenomenon. In addition, the alkaloid compounds and plant met abolites of noni may be linked to its apparent anti-inflammatory action. Plant sterols can assist in inhibiting the inflammatory response which causes swelling and pain. In addition, the antioxidant effect of noni may help to decrease free radical damage in joint cells, which can exacerbate discomfort and degeneration.

    Immune System

    The alkaloid and other chemical compounds found in noni have proven themselves to effectively control or kill over six types of infectious bacterial strains including: Escherichia coli, salmonellatyphi (and other types) , shigella paradysenteriae, and staphylo - coccus aureaus.25 In addition, damnacanthol, was able to inhibitt he early antigen stage of the Epstein- Barr virus.

    The bioactive components of the whole plant, combined or in separate portions, have demonst rat - ed the ability to inhibit several different strains of bacteria. Anecdotal reports support this action in that noni seems particularly effective in shortening the duration of certain types of infection. This may explain why noni is commonly used to treat colds and flu. The chemical constituents found in noni and the possibility that they stimulate xeronine production— as well as initiate alkaloid therapy—may explain noni’s reputation for having immuno-stimulatory properties. Alkaloids have been able to boost phagocytosis which is the process in which certain white blood cells called macrophages attack and literally digest infectious organisms. Interestingly, the ant it umoraction of noni has been ascribed to an immune system response which involves stimulating T-cells. tropical regions during World War II learned of the fruit’s ability to boost endurance and stamina. Native cultures in Samoa, Tahiti, Raratonga and Australia used the fruit in cooked and raw forms. M. citrifolia is considered a tonic and is especially recommended for debilitated conditions.

    Antioxidant

    The process of aging bombards the body with free radicals which can cause all kinds of degenerative diseases. The xeronine theory promoted by Dr. Heinicke submit s t hat as our bodies age, we lose our ability to synthesize xeronine. To make matters worse, the presence of many environment altoxins actually blocks the production of xeronine as well. He believes that the proxeronine content of Hawaiin noni fruit juice can help to block these actions, thereby working as an antiaging compound.26 The phytonutrients found in noni assist in promot - ing cell nourishment and prot ect ion from free radicals created by exposure to pollution and other potentially damaging agents. In addition, Morinda citrifolia contains selenium, which is considered one of the best antioxidant compounds available.

    Diabetes

    While scientific studies are lacking in this particular application of noni, Hawaiians used various parts of the plant and its fruit to treat blood sugar disorders. Anecdotal surveys have found t hat noni is current ly recommended for anyone with diabetes.

    Pain Killer

    A 1990 study found that extracts derived from the Morinda citrifolia root have the ability to kill pain in animal experiments.27 Interest ingly, it was during this study that the natural sedative action of the root was also noted. This study involved a French team of scientists who noted a significant central analgesic activity in laboratory mice.28 Dr. Heinicke has stated, “Xeronine also acts as a pain reliever. A man wit h very advanced int est inal cancer was given three months to live. He began taking the proxeronine and lived for a whole year, pain-free.” 29

    Skin Healing Agent

    One of the most prevalent hist rical uses of noni was in poultice form for cuts, wounds, abrasions, burns and bruises. Using its fruit extract for very serious burns has resulted in some extraordinary healing. Because skin is comprised of protein, it immediately responds to the presence of xeronine.

    burn site throught he direct application of a noni poultice is considered quite effective by Dr. Heinicke and his colleagues, who have studied enzymatic therapy. Concerning burns, he has written: I believe that each tissue has cells which contain proteins which have receptor sites for the absorption of xeronine. Certain of these proteins are the inert for ms of enzymes which require absorbed xeronine to become active. This xeronine, by converting the body’s procol- langenase system into a specific protease, quickly and safely removes the dead tissue from burns.30

    Drug Addiction

    The xeronine link to treat ing drug addiction is based on the notion that flooding t he brain with extra xeronine can reverse the neurochemical basis for addiction. This natural alkaloid is thought to normalize brain receptors which subsequent ly results in the cessation of physiological dependence on a certain chemical like nicotine.3 1 The potential of Hawaiin noni as a natural stimulat or for t he production of xeronine may have profound implications in treating various types of addictions.

    Complementary Agents of Noni

  • cat’s claw papaya
  • kava kava
  • pau d’arco
  • bioflavonoids
  • selenium
  • germanium
  • grapeseed extract
  • echinacea
  • proteolytic enzymes
  • aloe vera
  • glucosamine
  • shark
  • cartilage

    PrimaryApplications of Noni

  • abrasions
  • arthritis
  • atherosclerosis
  • bladder infections
  • boils bowel disorders
  • burns cancer
  • chronicfatigue syndrome
  • circulatory weakness
  • colds congest ion
  • cold sores constipation
  • depression diabetes
  • eye inf lammations fever
  • fract ures gastric ulcers
  • gingivit is headaches
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    GREEN TEA EXTRACT - For Antioxidant Support
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    Date: June 29, 2005 01:16 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: GREEN TEA EXTRACT - For Antioxidant Support

    Green Tea Extract

    For centuries the art of drinking and serving tea has played a major cultural role in many Asian countries. Americans are now discovering this healthful brew. Studies have shown that green tea is a powerful antioxidant that supports cardiovascular health and promotes dental health and glucose metabolism. The polyphenols are the most beneficial components in green tea, especially the catechin EGCG. Source Naturals offers two convenient ways to get the benefits of green tea: a highly concentrated, 100 mg GREEN TEA EXTRACT or the higher potency 500 mg GREEN TEA EXTRACT. Both extracts are standardized for polyphenols, particularly EGCG.

    The Tale of Tea

    Green, black and oolong teas are all processed from the young leaves of Camellia sinensis, a white-flowered evergreen that originated in southeastern Asia. Monks brought it to Japan and from there it spread around the world. The three basic types of tea are classified by processing method. Black tea is made by fermenting and roasting the leaves, giving it a dark color and rich taste. Oolong is partially fermented. Green tea is lightly steamed so it retains the chlorophyll of the leaf and its green color, along with high concentrations of polyphenol compounds.

    The Science of Green Tea

    All teas contain polyphenols, which are chemical compounds that act as antioxidants. In green tea the main polyphenols are the catechins, including gallocatechin (GC), epigallocatechin (EGC), epicatechin (EC), and epigallocatechin gallate (EGCG). Studies have shown that these catechins are the beneficial, health-promoting components of green tea, especially EGCG, a proven powerful antioxidant.

    Health Benefits

    Catechins have significant antioxidant power and may prove to be heart healthy agents in combating lipid peroxidation within the cell membranes that line arterial walls. Antioxidants neutralize destructive free radicals and support cardiovascular health by preventing the oxidation of cholesterol. Oxidized cholesterol is an unstable molecule that damages the integrity of arteries. Research shows that EGCG is a much more potent antioxidant than vitamin C or vitamin E. The catechins in green tea have been shown to fight foreign organisms and help prevent the plaque buildup that leads to poor dental health. Research shows that green tea also promotes healthy glucose levels in the blood stream by enhancing the action of insulin.

    Natural Wellness

    Nature provides us with special compounds that allow us to explore safe alternatives to support our health. Your local health food outlet is a great resource for nutritional education and effective, advanced natural products. Source Naturals is pleased to partner with these outlets to bring you innovative products like GREEN TEA EXTRACT. There is a wealth of research supporting the benefits of green tea. If drinking it isn’t your cup of tea, try Source Naturals concentrated GREEN TEA EXTRACTS - standardized for polyphenol content. Standardization provides you with the assurance that you are getting a consistent concentration of these compounds in each dose.

    References:
    Sakanaka S, Aizawa M, Kim M, Yamamoto T.1996. Inhibitory effects of green tea polyphenols on growth and cellular adherence of an oral bacterium, Porphyromonas gigivalis. Bioscience and Biotechnology of Biochemistry. (May) 60(5):745-749. Hodgson JM, Puddey IB, Croft KD, Burke V, Mori TA, Caccetta RAA, Beilin LJ. 2000. Acute effects of ingestion of black and green tea on lipoprotein oxidation. American Journal of Clinical Nutrition, (May) 71(5):1103-1107. Tsuneki H, Ishizukza M, Terasawa M, Wu JB, Sasaoka T, Kimura I. 2004. Effect of green tea on blood glucose levels and serum proteomic patterns in diabetic (db/db) mice and on glucose metabolism in healthy humans. BMC Pharmacology 4:18.

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    CHITOSAN: The Fiber that Binds Fat
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    Date: June 25, 2005 07:55 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: CHITOSAN: The Fiber that Binds Fat

    Overview

    Chitosan is a natural product that inhibits fat absorption. It has the potential to revolutionize the process of losing weight and by so doing, reduce the incidence of some of the most devastating Western diseases we face today. Chitosan is indigestable and non-absorbable. Fats bound to chitosan become nonabsorbable thereby negating their caloric value. Chitosan-bound fat leaves the intestinal tract having never entered the bloodstream. Chitosan is remarkable in that it has the abilty to absorb an average of 4 to 5 times its weight in fat.60

    The same features that allow chitosan to bind fats endow it with many other valuable properties that work to promote health and prevent disease. Chitosan is a remarkable substance whose time has come.


    Chitosan: A Brief History

    Chitin, the precursor to Chitosan, was first discovered in mushrooms by the French professor Henri Braconnot in 1811.61 In the 1820’s chitin was also isolated from insects.62 Chitin is an extremely long chain of N-acetyl-D-glucoseamine

    FIGURE 2.
    a) Chitosan full structure
    b) Abbreviated Chitosan structure
    c) Fanciful "crab oligomer" Chitosan structure showing functional claw

    glucoseamine units. Chitin is the most abundant natural fiber next to cellulose and is similar to cellulose in many respects. The most abundant source of chitin is in the shells of shellfish such as crab and shrimp. The worldwide shellfish harvest is estimated to be able to supply 50,000 tons of chitin annually.63 The harvest in the United States alone could produce over 15,000 tons of chitin each year.64

    Chitin has a wide range of uses but that is the subject of another book. Chitosan was discovered in 1859 by Professor C. Rouget.65 It is made by cooking chitin in alkali, much like the process for making natural soaps. After it

    ----------------------------------
    • Waste Water Purification • Stabilizing Oil Spills • Stabilizing Fats in Food Preparation • Antibacterial Protection for Seeds • Flavor Stabilizer • Stabilizes Perishable Fruits/Vegetables • Ion Exchange Media • Bacterial Immobilizer • Cosmetic and Shampoo Additive • Tableting Excipient • Absorbant for Heavy Metal Removal
    Table 5. Industrial Uses of Chitosan 66-75

    ----------------------------------
    • Absorbs and Binds Fat • Promotes Weight Loss • Reduces LDL Cholesterol • Boosts HDL Cholesterol • Promotes Wound Healing • Antibacterial/Anticandida/Antiviral • Acts as Antacid • Inhibits the Formation of Plaque/Tooth Decay • Helps Control Blood Pressure • Helps Dental Restoration/Recovery • Helps to Speed Bone Repair • Improves Calcium Absorption • Reduces Levels of Uric Acid
    Table 6. Health and Nutrition Uses of Chitosan 60,66,77-107

    is cooked the links of the chitosan chain are made up of glucosamine units. Each glucosamine unit contains a free amino group. These groups can take on a positive charge which gives chitosan its amazing properties. The stucture of chitosan is represented schematically in Figure 2. Research on the uses of chitin and Chitosan flourished in the 1930s and early 1940s but the rise of synthetic fibers, like the rise of synthetic medicines, overshadowed the interest in natural products. Interest in natural products, including chitin and chitosan, gained a resurgence in the 1970s and has continued to expand ever since. Uses of Chit osan Some of Chitosan's major uses—both Industrial and Health and Nutritional—are listed in Tables 5 and 6.

    Water Purification

    Chitosan has been used for about three decades in water purification processes. 67 When chitosan is spread over oil spills it holds the oil mass together making it easier to clean up the spill. Water purification plants throughout the world use chitosan to remove oils, grease, heavy metals, and fine particulate matter that cause turbidity in waste water streams.

    Fat Binding/ Weight Loss

    Like some plant fibers, chitosan is not digestible; therefore it has no caloric value. No matter how much chitosan you ingest, its calorie count remains at

    ------------------------------
    Dietary Fiber % Fat Excreted Dietary Fiber %Fat Excreted Chitosan 50.8 + 21.6 Carrageen 9.6 + 1.9 Kapok 8.3 + 1.1 Sodium Alginate 8.1 + 2.2 Pectin 7.4 + 1.9 Locust Bean 6.0 + 1.8 Guar 6.0 + 1.7 Konjak 5.2 + 0.6 Cellulose 5.1 + 2.1 Karaya 4.9 + 1.5 Acacia 4.6 + 0.9 Furcellaran 4.4 + 0.9 Chitin 4.3 + 1.0 Agar 2.8 + 0.4
    TABLE 7. Effects of Dietary Fibers on Fecal Lipid Excretion 109,110

    fibers, chitosan’s unique properties give it the ability to significantly bind fat, acting like a “fat sponge” in the digestive tract. Table 7 shows a comparison of chitosan and other natural fibers and their ability to inhibit fat absorption. Under optimal conditions, Chitosan can bind an average of 4 to 5 times its weight with all the lipid aggregates tested.60 (NOTE: This assessment was made without the addition of ascorbic acid which potentiates this action even further.77 Studies in Helsinki have shown that individuals taking chitosan lost an average of 8 percent of their body weight in a 4-week period.76 Chitosan has increased oil-holding capacity over other fibers.108 Among the abundant natural fibers, chitosan is unique. This uniqueness is a result of chitosan’s amino groups which make it an acid absorbing (basic) fiber. Most natural fibers are neutral or acidic. Table 7 summarizes the in vivo effects in animals of various fibers on fecal lipid excretion. As can be seen from the results listed, ingestion of chitosan resulted in 5-10 times more fat excretion than any other fiber tested. D-Glucosamine, the building block of chitosan, is not able to increase fecal fat excretion. This is due to the fact that glucosamine is about 97 percent absorbed while chitosan is nonabsorbable. Fats bound to glucosamine would likely be readily absorbed along with the glucosamine. Chitosan, on the other hand, is not absorbed and therefore fats bound to chitosan can not be absorbed.

    Cholesterol Control

    Chitosan has the very unique ability to lower LDL cholesterol (the bad kind) while boosting HDL cholesterol (the good kind).78 Laboratory tests performed on rats showed that “chitosan depresses serum and liver cholesterol levels in cholesterol- fed rats without affecting performance, organ weight or the nature of the feces.”79 Japanese researchers have concluded that Chitosan “appears to be an effective hypocholesterolemic agent.”80 In other words, it can effectively lower blood serum cholesterol levels with no apparent side effects. A study reported in the American Journal of Clinical Nutrition found that Chitosan is as effective in mammals as cholestryramine (a cholesterol lowering drug) in controlling blood serum cholesterol without the deleterious side effects typical of cholestryramine. 81 Chitosan decreased blood cholesterol levels by 66.2 percent.82 It effectively lowered cholesterol absorption more than guar gum or cellulose.83 Laboratory test results indicated that a 7.5% chitosan formula maintained adequate cholesterol levels in rats, despite a dramatic increase in the intake of cholesterol. 84

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    Herbal Forms
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    Date: June 25, 2005 10:52 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Herbal Forms

    Herbal Forms

    Extract: An extract made from ginkgo leaves is available in Europe and is used for cerebral arteriosclerosis in peripheral circulatory disorders of the elderly.

    Tincture: Ginkgo tincture is often combined with other herbs such as periwinkle and used for circulatory problems and venous disorders.

    Infusion: Infusions of ginkgo are used for arteriosclerosis, varicose veins and hemorrhoids.

    Capsules: Powd e red forms of ginkgo can be used to enhance brain function and memory.

    Storage: Keep in a dark container in a cool, dry environment.

    Regulatory Stauts:
    U.S.: none
    U.K.: none
    Canada: none
    France: over-the-counter drug status
    Germany: over-the counter drug status

    Recommended Usage: Ginkgo should be taken in normal dosages and, if possible, at the same times eve ry day. In the case of ginkgo, taking it consistently for 12 weeks is recommended. Although injections of Gingko have sometimes been used, oral ingestion of a tablet or capsule is therapeutically effective. More advanced p reparations of ginkgo make it possible to obtain higher concentrations of flavoglycosides in smaller amounts of extract.

    Safety: Ginkgo extracted from the leaves of the ginkgo tree is considered nontoxic and is virtually without side-effects. It can be safely used with other supplements without interaction and has no reported toxicity. In rare cases, some gastric upset or incidence of headache or skin rash have occurred, which may indicate that the individual is allergic to the substance. The fruit pulp of ginkgo can produce seve re contact dermatitis and other allergic reactions. The leaf extract of ginkgo is usually the only form that is available and is extremely safe.

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    ENDNOTES
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    Date: June 23, 2005 11:50 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: ENDNOTES

    ENDNOTES


    1 G.A. Cordell and O.E. Araujo, “Capsaicin: Identification, nomenclature, and pharmacotherapy.” Ann. Pharmacother. 27: 1993, 330-336.
    2 A.Y. Leung. Encyclopedia of Common Natural Ingredients used in Food. (John Wiley and Sons, New York: 1980.
    3 Cordell, 330-36.
    4 J.J. Jang, D.E. Defor, D.L. Logsdon and J.M. Ward. “A 4-week feeding study of ground red chile (Capsicum annuum) in male mice.” F o o d - C h e m - T o x i c o l . S e p t . 1992 30 (9): 783-7.
    5 John R. Christopher. Capsicum. (Christopher Publications, Springville, Utah: 1980), 27.
    6 Jack Ritchason. The Little Herb Encyclopedia, 3rd ed. (Woodland Publishing, Pleasant Grove, Utah: 1994), 44.
    7 Christopher, 4.
    8 Juliette Bairacli-Levy. Common Herbs for Natural Health. (Schocken Books, New York: 1974), 41-43.
    9 Charles B. Heiser. Nightshades. (W.H. Freeman, San Francisco: 1969), 18.
    10 Lenden H. Smith, M.D., E.P. Donatelle, M.D., Vaughn Bryant, Ph.D. et al. Basic Natural Nutrition. (Woodland Books, Pleasant Grove, Utah: 1984), 157.
    11 J. Jurenitsch et al. “Identification of cultivated taxa of Capsicum: taxonomy, anatomy and composition of pungent principle.” Chemical Abstracts. 91 July 30, 1977: 35677g.
    12 Daniel B. Mowrey. The Scientific Validation of Herbal Medicine. (Keats Publishing, New Canaan, Connecticut: 1986), 159.
    13 Ibid., 208-09.
    14 Michael T. Murray. The Healing Power of Herbs, 2nd ed. (Prima Publishing, Prima, California: 1995), 71.
    15 J. De Lille and E. Ramirez. “Pharmacodynamic action of the active principles of chile (capsicum annuum L.) Anales Inst. Biol. 1935: 6, 23-37. See also C.C. Toh, T.S. Lee et al. “The pharmacological actions of capsaicin and its analogues.” B r i t i s h Journal of Pharmacology. 1955: 10, 175-182.
    16 N.A. Castle. “Differential inhibition of potassium currents in rat ventricular myocytes by capsaicin.” Cardiovasc-Res. Nov. 1992, 26 (11): 1137-44.
    17 Murray, The Healing Power of Herbs, 72.
    18 Ritchason, 46.
    19 T. Kawada, et al. “Effects of capsaicin on lipid metabolism in rates fed a high fat diet.” Journal of Nutrition. 1986: 116, 1272-78. See also J.P. Wang, et al. “Antiplatelet effect of capsaicin.” Thrombosis Res. 1984: 36, 497-507, and S. Visudhiphan, et al. “The relationship between high fibrinolytic activity and daily capsicum ingestion in Thais.” American Journal of Clinical Nutrition. 1982: 35, 1452-58.
    20 K. Sambaiah and N. Satyanarayana. “Hpocholesterolemic effect of red pepper and capsaicin.” Indian Journal of Experimental Biology. 1980: 18, 898-99. See also M.R. Srinivasan, et al. “Influence of red pepper and capsaicin on growth, blood constituents and nitrogen balance in rats.” Nutrition Reports International. 1980: 21 (3): 455-67.
    21 Mowrey, 12.
    22 Ibid.
    23 Toh, 175-182.
    24 Mowrey, 12.
    25 Ibid., 19-20.
    26 Louise Tenney. The Encyclopedia of Natural Remedies. (Woodland Publishing, Pleasant Grove, Utah: 1995), 42. See also Peter Holmes. The Energetics of Western Herbs. (Artemis Press, Boulder: 1989), 322.
    27 Y. Lee, et al. “Flavonoids and antioxidant activity of fresh pepper (Capsicum annuum) cultivars.” Journal of Food Science. May 1995: 60 (3): 473-76. See also L.R. Howard, et al. “Provitamin A and ascorbic acid content of fresh pepper cultivars (Capsicum annuum) and processed jalapenos.” Journal of Food Science. M a r c h , 1994: 59 (2): 362-65.
    28 J.J. Espinosa-Aguirre, et al. “Mutagenic activity of urban air samples and its modulation by chile extracts.” Mutat-Res. Oct. 1993: 303 (2): 55-61.
    29 Ibid.
    30 Howard, 362-65.
    31 Z. Zhang, S.M. Hamilton, et al. “Inhibition of liver microsomal cytochrome P450 activity and metabolism of the tobacco-specific nitrosamine NNK by capsaicin and ellagic acid.” Anticancer-Res. Nov-Dec. 1993: 13 (6A): 2341-46.
    32 C.H. Miller, Z. Zhang, et al. “Effects of capsaicin on liver microsomal metabolism of the tobacco-specific nitrosamine NNK.” Cancer-Lett. Nov. 30, 1993: 75 (1): 45- 52.
    33 Murray, The Healing Power of Herbs, 71.
    34 Cordell, 330-36. See also Murray, The Healing Power of Herbs, 70-71.
    35 Murray, The Healing Power of Herbs, 72.
    36 C.P.N. Watson, et al. “The post-mastectomy pain syndrome and the effect of topical capsaicin.” Pain. 1989: 38, 177-86. See also C.P.N. Watson and R.J. Evans. “The post-mastectomy pain syndrome and topical capsaicin: A randomized trial.” Pain. 1992: 51, 375-79.
    37 Murray, The Healing Power of Herbs, 73.
    38 Watson, 177-86.
    39 C. Nelson. “Heal the burn: Pepper and lasers in cancer pain therapy.” Journal of the National Cancer Institute. 1994: 86, 1381.
    40 Ibid.
    41 “The capsaicin study group: Effect of treatment with capsaicin on daily activities of patients with painful diabetic neuropathy.” Diabetes Care. 1992: 15, 159-65. See also R. Tanden, et al. “Topical capsaicin in painful diabetic neuropathy. Effect on sensory function.” Diabetes Care. 1992: 15, 8-14, K.M. Basha and F.W. Whitehouse. “Capsaicin: A therapeutic option for painful diabetic neuropathy.” Henry Ford Hospital Medical Journal. 1991: 39, 138-40, and M.A. Pfeifer, et al. “A highly successful and novel model for treatment of chronic painful diabetic peripheral neuropathy.” Diabetes Care. 1993: 16, 1103-15.
    42 R. Tanden, et al. “Topical capsaicin in painful diabetic neuropathy: controlled study with long- term follow-up.” Diabetes Care. Jan. 1992: 15 (1): 8-14.
    43 Ibid.
    44 J.E. Bernstein, et al. “Topical capsaicin treatment of chronic post-herpetic neuralgia (shingles) with topical capsaicin. A preliminary study. Journal of American Academy of Dermatologists. 1987: 17, 93-96. See also Murray, The Healing Power of Herbs, 72.
    45 Sid Kircheimer. The Doctor’s Book of Home Remedies. (Rodale Press, Emmaus, Pennsylvania: 1993), 228.
    46 Murray, The Healing Power of Herbs, 74.
    47 G.M. McCarthy and D.J. McCarty. “Effect of topical capsaicin in therapy of painful osteoarthritis of the hands.” Journal Rheumatol. 1992: 19, 604-07. See also C. L Deal, et al. “Treatment of arthritis with topical capsaicin: A double blind trial.” Clinical Therapy. 1991: 13, 383-95.
    48 Murray, The Healing Power of Herbs, 74.
    49 Kircheimer, 14.
    50 Murray, The Healing Power of Herbs, 74.
    51 Michael T. Murray, N.D. and Joseph Pizzorno, N.D. Encyclopedia of Natural Medicine. (Prima Publishing, Rocklin, California: 1991), 419.
    52 J. Y. Kang, et al. “The effect of chile ingestion of gastrointestinal mucosal proliferation and azoxymethane-induced cancer in the rat.” Journal of Gastroenterology- Hepatol. Mar-Apr. 1992: 7 (2): 194-98.
    53 K. G. Yeoh, et al. “Chile protects against aspirin-induced gastroduodenal mucosal injury in humans.” Dig-Dis-Sci. Mar. 1995: 40 (3): 580-83.
    54 Ibid.
    55 Ibid.
    56 L. Limlomwongse, et al. “Effect of capsaicin on gastric acid secretion and mucosal blood flow in the rat.” Journal of Nutrition. 1979: 109, 773-
    77. See also T. Kolatat and D. Chungcharcon. “The effect of capsaicin on smooth muscle and blood flow of the stomach and the intestine.” Siriraj Hospital Gazette. 1972: 24, 1405-18, O. Ketusinh, et al. “Influence of capsaicin solution on gastric acidities.” A m e r i c a n Journal of Proceedings. 1966: 17, 511-15, and Mowrey, 48.
    57 Mowrey, 48 and Limlomwongse, 773-77.
    58 M. Horowitz, et al. “The effect of chile on gastrointestinal transit.” Journal of Gastroenterology-Hepatol. Jan-Feb, 1992 7 (1): 52-56.:
    59 Christopher Hobbs. “Cayenne, This Popular Herb is Hot.” Let’s Live. April 1994: 55.
    60 V. Badmaev and M. Majeed. “Weight loss, the Ayurvedic system.” Total Health. Aug, 1995: 17 (4): 32-35.
    61 Murray, The Healing Power of Herbs, 75.
    62 C.N. Ellis, et al. “A double-blind evaluation of topical capsaicin in pruritic psoriasis.” Journal of the American Academy of Dermatology. 1993: 29 (3): 438-42.
    63 Murray, The Healing Power of Herbs, 75.
    64 S. Marabini, et al. “Beneficial effect of intranasal applications of capsaicin in patients with vasomotor rhinitis.” Eur Arch-Otorhinolaryngol. 1991: 248 (4): 191-94.
    65 Ibid.
    66 Mowrey, 242.
    67B. Dib. “Effects of intrathecal capsaicin on autonomic and behavioral heat loss responses in the rat. Pharmacol Biochem Behav. 1987: 28, 65-70.
    68 Murray, The Healing Power of Herbs, 72.
    69 Christopher, 31.
    70 M. Ponce, et al. “ In vitro effect against giardia of 14 plant extracts.” Rev-Invest-Clin. Sept- Oct. 1994: 46 (5): 343-47.
    71 Ibid.
    72 Humbart Santillo. Natural Healing with Herbs. (Hohm Press, Prescott, Arizona: 1993), 100.
    73 Daniel B. Mowrey. “Capsicum ginseng and gotu kola in combination.” The Herbalist premier issue, 1975: 22-28.
    74 Ibid.
    75 Mowrey, The Scientific Validation of Herbal Medicine, 102.
    76 J. Roquebert, et al. “Study of vasculotropic properties of Capsicum annuum.” Annales Pharmaceutiques Francaises. 1978: 36 (7-8): 361-68.
    77 Rita Elkins. Depression and Natural Medicine. (Woodland Publishing, Pleasant Grove, Utah: 1995), 161.



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    Stomach Ulcers
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    Date: June 23, 2005 11:24 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Stomach Ulcers

    Stomach Ulcers

    Ironically, if you suffer from a peptic or duodenal ulcer, the last thing you feel probably feel inclined to take is hot Cayenne Pepper. While it goes against eve rything we’ve ever heard about what aggravates an ulcer, the facts are that most “spicy” foods do just the opposite. Capsicum has the ability to serve as a local anesthetic to ulcerated tissue and can even help to control bleeding. While some individuals may be bothered by eating “peppery” or spicy foods, these foods do not cause the formation of gastric ulcers in normal people. What is particularly interesting is that people suffering from ulcers who would normally avoid Cayenne Pepper, may actually benefit from its therapeutic action. In addition, taking Capsicum may significantly reduce the risk of ever developing a peptic ulcer. A Chinese study published in 1995 stated, “Our data supports the hypothesis that the chile used has a protective effect against peptic ulcer disease.”52 Another 1995 study found that Capsicum can even protect the stomach lining from aspirin induced ulcers.5 3 As most of us are aware, aspirin can cause stomach ulceration in certain individuals if a sensitivity exists or if taken with too little liquid. Researchers concluded after experiments with human volunteers that the capsaicin content of capsicum has a pronounced gastro - protective effect on the mucous membranes of the stomach.5 4 Eighteen healthy volunteers with normal gastrointestinal mucosa took chile and water followed by 600 mg of aspirin and water. The study was conducted over a period of four weeks. Endoscopy results showed that taking 20 gm of chile before the aspirin definitely demonstrated a protective action on the stomach lining.55 In short, Capsicum has the ability to rebuild stomach tissue. Note: The ability of Capsicum to bring blood to regions of tissue at a faster rate boosts the assimilation of foods that are consumed with it.56 Several clinical studies support this phenomenon. It is thought that Capsicum initiates the release of certain substances which increase secretions and facilitate better profusion of blood to the stomach and intestines.57 Capsicum can increases the flow of digestive secretions from the salivary, gastric and intestinal glands. Capsicum and the Gastro-Intestinal Tract In 1992, researchers tested the effect of chile or Capsicum on gastrointestinal emptying. Eight healthy volunteers were evaluated before and after the addition of Capsicum to their meals. The results conclusively demonstrated that the ingestion of Capsicum greatly effects intestinal transit time.58 If food moves faster through from the stomach through the intestines, caloric assimilation and bowel evacuation may be influenced for the better. Capsicum seems to “speed up” various physiological processes. To add transit time to the list of functions Capsicum boosts comes as somewhat of a surprise and additional benefit. Capsicum and Weight Loss Capsicum may be an unheralded weight loss aid that is perfectly safe to use. Studies have suggested that Capsicum can slow fat absorption in the small intestines and actually boost the metabolic rate so the thermogenesis (fat burning) is enhanced.5 9 In many instances excessive weight gain is thought to be a result of a sluggish metabolism. Capsicum has been singled out by herbalists as an herb which may boost the burning of fat.60 Unlike other stimulants, Capsicum does not cause palpitations, hyperactivity or a rise in blood pressure. For this reason, it may be a valuable weight loss supplement that has been generally overlooked.

    Psoriasis

    As mentioned earlier, capsaicin has the ability to inhibit a neurotransmitter called substance P. Interestingly, an excess of substance P has been associated with psoriasis. Michael T. Murray, in his book, The Healing Power of Herbs, points out that this finding led researchers to study the effects of capsaicin ointments on psoriasis .61 Regarding the use of such an ointment for psoriasis, he states: “ . . . In one double-blind study, forty-four patients with symmetrically distributed psoriasis lesions applied topical capsaicin to one side of their body and a placebo to the other side. After 3 to 6 weeks, significantly greater reductions in scaling and redness were observed on the capsaicint reated side. Burning, stinging, itching, and skin redness were noted by nearly half of the patients initially, but these diminished or vanished on continued applications.”62 There is no question that capsaicin based ointments should be employed for psoriasis. Tests have conclusively found that treating psoriasis with capsaicin caused significant improvement in a variety of symptoms as well as the severity of the attack.63

    Rhinitis

    Capsicum has also scientifically proven its value in people suffering from vasomotor rhinitis. By using Capsicum in spray form, researchers found that it was able to significantly reduce nasal obstruction and secretion.64 It is important to understand that in these particular instances, a Capsicum solution was applied directly to the mucous membranes of the nose. It did initially cause a painful burning and stimulated nasal secretion. However, in time, after repeated applications, these side effects disappeare d .6 5 Apparently, Capsicum may block the action of peripheral nerve endings which may stimulate nasal secretion and blockage. More study of Capsicum as a viable treatment for rhinitis has been recommended. Note: One of the many pro p e rties of Capsicum is its ability to b reak up mucous congestion which makes expectoration much easier.66 For this reason, Capsicum is recommended for upper respiratory infections which are characterized by excess mucus.

    Fever and Chills

    While it may seem somewhat contradictory, Capsicum actually l owers the temperature of the body by stimulating the region of the hypothalamus, which cools the body.6 7 “The ingestion of cayenne peppers by cultures native to the tropics appears to help these people deal with high temperature s . ”68 Capsicum also pro- motes perspiration which helps to cool the body off. In tropical areas, local people eat substantial amounts of hot peppers on a daily basis which helps to boost the elimination of sweat and thereby keeps body temperature down. This same mechanism can be used to treat fever and chills. In addition to this action, using Capsicum for any infection that may be causing a fever is also warranted. Capsicum helps to boost immune defenses and fights microorganism invasion.

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    CLINICAL APPLICATIONS OF CAPSICUM
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    Date: June 23, 2005 11:20 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: CLINICAL APPLICATIONS OF CAPSICUM

    CLINICAL APPLICATIONS OF CAPSICUM

    Capsicum is a remarkable whole body stimulant that can boost blood flow, tone the nervous system, relieve indigestion, promote sweating, help to cauterize and heal ulcers, ease persistent pain and fight off infection. One very authoritative work on African plants suggests that Capsicum’s “regular ingestion is highly beneficial in hemorrhoids, varicose veins, anorexia, liver congestion and vascular conditions . . .the indigenous inhabitants of Africa and of the Antilles are remarkably free form all of these conditions as they use Capsicum fruit in their diet.”10 Most of the therapeutic actions of Capsicum are attributed to the alkaloid or glucoside content of the herb.11 The latest scientific studies conducted with Capsicum will be discussed in subsequent sections.

    Herbal Catalyst

    Because Capsicum boosts peripheral circulation and stimulates organ secretion, it expedites the therapeutic delivery and action of other herbs. In other words, the medicinal benefits of these herbs reach infected or inflamed tissue more rapidly due to enhanced blood flow.12 Consider the following statement: “Cayenne will insure the rapid and even distribution of the active principles of the rest of the herbs to critical function - al centers of the body, including those involved in cellular respiration, metabolism, data transmission, and neural-hormonal activation. Cayenne is included in several other blends for this reason. In extremely small quantities it can dramatically increase the efficiency of most other herbs.”13 Many health practitioners believe that the key to healing is CAPSICUM stimulation. Capsicum stimulates eve rything from blood flow to peristaltic action in the stomach, to intestinal transit time. The re m a rkable ability of Capsicum to stimulate organ secretion and even heart action makes it one of the strongest natural stimulants known. Se veral different kinds of herbal blends targeting various body systems will utilize Capsicum to boost the formula’s efficacy.

    Cardiovascular Tonic

    Capsicum is said to be unequaled for its ability to boost circulation and increase heart action. Interestingly, cultures who consume significant amounts of cayenne pepper in their diet have much lower rates of cardiovascular disease.14 Capsicum exerts a variety of desirable actions on the entire card i ovascular system. It has the extraordinary ability to enhance cardiovascular performance while actually lowering blood pressure.15 A quote taken from a card i ovascular publication re a d s , “Capsaicin has also been shown to prolong cardiac action potential in atrial muscle . . .”16 Michael T. Murray, N.D., has stated, “ Cayenne pepper [Capsicum] should be recommended as a food for its beneficial antioxidant and cardiovascular effects.”17 Herbalists have considered Capsicum as a superior “f o o d” for the heart. In fact, in cases where a heart attack is suspected administering capsicum in hot water has been thought to help lessen the severity of the attack. Capsicum can also be placed on or under the tongue in emergencies involving heart attack, stroke or hemorrhaging. 18 Note: Using Capsicum for any heart-related problem, especially a suspected heart attack should never take the place of medical attention or a physician’s care.

    CAPSICUM Blood Cholesterol Reducer

    Various studies have conclusively demonstrated that Capsicum reduces the risk of developing atherosclerosis (hardening of the a rteries) by reducing blood cholesterol and triglyceride levels .19 Additional clinical studies conducted in India found that when cayenne was ingested along with dietary cholesterol, the typical rise in liver and blood serum cholesterol levels was significantly inhibited. In addition, bile acids and free cholesterol were subsequently eliminated from the body through the stool.20 Interestingly, these tests revealed that using Capsicum was actually more effective in reducing cholesterol that capsaicin alone.2 1 Daniel Mowrey, Ph.D., emphatically points out that this is just one of many examples of the superiority of whole botanicals as opposed to their isolated components.22 Note: Using Capsicum in combination with Hawthorn is a particularly good cardiovascular tonic.

    Blood Pressure Equalizer

    While an added bonus of Capsicum’s capability to lower blood serum cholesterol is a decrease in blood pressure, additional evidence strongly suggests that the herb initiates other mechanisms that fight hypertension .23 “Cayenne, according to another study, also reduces the blood pressure in an even more direct manner: a number of years ago, a team of researchers discove red that capsaicin acts in a reflexive manner to reduce systemic blood pressure, a kind of coronary chemoreflex.”24 Adding Garlic to Capsicum creates an even better therapeutic blend for treating hypertension.

    Blood Detoxification CAPSICUM

    “Cayenne is a kind of catalyst in the blood purification process . . . it acts as a diaphoretic, stimulating the excretion of wastes in the swe a t . ”25 Because Capsicum stimulates organ secretion and boosts peripheral blood flow, it would only stand to reason that it would also facilitate the faster removal of toxins from the bloodstream and lymphatic system. You may have already noticed that Capsicum is frequently added to blood-purifying herbal combinations. Circulatory Booster Researchers have found that the simulating action of Capsicum on surface capillaries can help to pre vent cold hands and feet.2 6 For this reason, it may be helpful for Reynaud’s Syndrome. Old remedies using Capsicum have even recommended placing it in socks to warm the feet and to help prevent frostbite. An old folk cure for a chilled body was a steaming hot cup of Capsicum tea. Free Radical Scavenger The rich flavonoid content of Capsicum gives it significant antioxidant capabilities. A recent study conducted in 1995 showed that Capsicum has a higher ascorbic acid content than chiles from the jalapeno or serrano varieties .27 Vitamin C and bioflavonoids can scavenge for dangerous free radicals which cause tissue damage and can predispose organs to degenerative diseases. Free radicals are found everywhere and are created as by-products of metabolic p rocesses including the act of breathing itself. Pollutants can expose the body to free radicals. An interesting study done in Mexico City and published in 1993 found that Capsicum extract was able to modulate the mutagenic activity of urban air samples.28 In other words, these potentially dangerous nitro - a romatic compounds found in polluted air were kept from mutating by red chile extract.29 Chemical breakdowns of Capsicum have also found that CAPSICUM the pepper is high in Provitamin A, which significantly contributes to its healing ability and immune fortification.30 Anti-Carcinogenic Compound Anti-cancer research recently tested Capsicum on laboratory rats and found that it does indeed demonstrate anti-cancer properties by inhibiting certain enzymes which can initiate the mutation of cells.31 What this implies is that taking Capsicum can afford the body some protection against the cellular mutation which occurs in malignant growths. Capsicum actually inhibited the formation of dangerous metabolites under laboratory conditions where they should have normally been activa t e d .3 2 This study implies that Capsicum may have many more sophisticated bio-chemical actions than previously thought.

    An Impressive Pain Killer

    Capsaicin has recently emerged as a remarkably effective pain reliever and has become the subject of recent clinical research . Applying capsaicin in cream or ointment form to painful joints, scar tissue or other painful conditions involving peripheral nerves confuses pain transmitters. In other worlds, capsaicin temporarily disrupts sensory nerve cell biochemistry there by impeding the relay of pain sensations from the skin surface. It does this by inhibiting a neurotransmitter called substance P. This specific compound is thought to be the main mediator of pain impulses from peripheral nerve endings.33 Substance P has also demonstrated its ability to inhibit inflammatory pain generated in arthritic joints in much the same way.34 Today, several over-the-counter topical preparations utilize capsaicin for the pain of arthritic joints. The ability of Capsicum to control severe and unresponsive pain is significant, to say the least. Modern clinical utilization of topical capsaicin may offer signifi-cant relief for a number of painful conditions including: diabetic neuropathy, cluster headaches, post-amputation pain, post-mastectomy pain, shingles and painful scar tissue.35

    POST-SURGICAL PAIN

    In the early spring of 1996, prime time national news show s reported that scientists had found that individuals who had suffered from chronic pain in post-surgical scars (heart bypass, arterial grafts, etc.) were successfully treated with topical preparations containing capsaicin. While this may have been news to many of us, clinical studies had been already published for several years that capsaicin held profound value for various kinds of pain which did not respond to established medical treatments. Typically surgical scars and regions around them can produce persistent pain or can be very sensitive to the touch even when completely healed. This type of pain phenomenon seems to respond well to capsaicin ointments and creams.

    POST-MASTECTOMY PAIN

    When capsaicin preparations were applied following mastectomy or breast reconstruction, pain was significantly relieved. Se veral double blind studies found that using capsaicin creams four times daily for 4 to 6 weeks resulted in much less frequent occurrence of sharp, jabbing pain.3 6 All thirteen patients studied had a 50 percent or greater improve m e n t .3 7 Various unpleasant sensations other than pain also improved with topical applications of capsaicin creams.38

    MOUTH SORES FROM RADIATION OR CHEMOTHERAPY

    A fascinating study conducted at the Yale Pain Management Center discove red that capsaicin could ve ry significantly lessen pain caused by mouth sores which frequently develop after chemotherapy or radiation.39 Apparently delivering the capsaicin in the form of soft candy (taffy) enabled the substance to be retained in the mouth long enough to desensitize the nerve endings causing the pain. Each one of the eleven case studies re p o rted that their pain had decreased and in two patients, it stopped entirely.40

    DIABETIC NEUROPATHY

    Diabetic neuropathy is a painful nerve condition which can develop in cases of prolonged diabetes. Several double-blind studies have supported the considerable value of capsaicin creams for relieving the pain associated with this disorder.41 The results of a controlled study using Capsicum for seve re cases of diabetic neuropathy which did not respond to conventional therapy were published in 1992. A cream containing Capsicum was applied to painful areas four time a day and pain was carefully e valuated for 8 weeks at two-week intervals. The results we re impressive, to say the least. In the 22 patients who used the Capsicum the following results we re re c o rded: “Capsaicin tre a tment was more beneficial than vehicle treatment in the overall clinical improvement of pain status, as measured by physician’s global evaluation and by a categorical pain severity scale . . . In a follow-up study, approximately 50 percent of the subjects reported improved pain control or were cured . . .”42 No t e : While there was a burning sensation when the Capsicum c ream was first applied, some subjects found that its magnitude and duration lessened with continued application.43

    SHINGLES

    The FDA has approved capsaicin-based ointments for the treatment of pain that results from diseases like shingles. Again, numerous studies have documented the value of capsaicin for decreasing the miserable nerve-related pain associated with shingles. The general consensus derived from these tests were that approximately 50 p e rcent of people suffering from shingles responded well to capsaicin creams, some even after 10 to 12 months.44

    Note: If blisters accompany a shingles outbreak, it is better to wait until they have healed before using any capsaicin-based ointments or creams.

    RELIEF FOR BURNING FEET

    Frequently an uncomfortable “burning” sensation in the feet will occur in many people, particularly in diabetics. As ironic as it may seem, using capsaicin creams may actually alleviate this burning. “In various studies, diabetics who treated their burning feet with capsaicin got greater improvement and we re able to walk more easily than those not using the cream.”45 In addition, using topical applications of capsaicin as opposed to strong, oral drugs is much more preferable.

    ARTHRITIS PAIN

    Clinical tests have confirmed that topical capsaicin ointments substantially alleviate the miserable pain that characterizes osteoand rheumatoid arthritis.46 These studies revealed that using 0.075 capsaicin cream reduced tenderness and pain.47 Dr. Michael T. Murray writes: “ . . . seventy patients with osteoarthritis and thirty - one with rheumatoid arthritis received capsaicin or placebo for 4 weeks. The patients were instructed to apply 0.025 percent capsaicin cream or its placebo to painful knees four times daily. Significantly more relief of pain was reported by the capsaicin-treated patients than by the placebo patients throughout the study . . .”48 Anyone suffering from osteo or rheumatoid arthritis should evaluate the effectiveness of capsaicin ointments for joint pain. Ester Lipstein-Kresch, M.D., has studied the effectiveness of capsaicin creams for arthritis and has stated: “You need to apply it three or four times a day on the affected area for at least two weeks before you’ll see any improvement. An initial burning sensation at the site is not unusual for the first few days, but this goes away with continued application.”49 Note: Capsaicin is also useful for tennis elbow due to its ability to block the transmission of pain.

    MIGRAINE HEADACHES (CLUSTER TYPE)

    Topical applications of capsaicin ointments intranasally may also help to relieve the pain of a specific kind of migraine headache called cluster headaches. Cluster headaches are characterized by s e ve re pain which typically radiates around one eye. The term “cluster” refers to the fact that these headaches tend to occur in clusters of one to three per day and can recur at intervals. Headache pain and severity we re reducing in groups using intranasal capsaicin.5 0 This type of capsaicin treatment should be done under a physician’s care. There is some speculation that capsaicin may be more effective in pre venting migraines before they develop into a full blown attack.51

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    Probiotics - Our Friendly Bacteria
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    Date: June 16, 2005 10:51 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Probiotics - Our Friendly Bacteria

    Probiotics Our Friendly Bacteria

    An estimated 10 quadrillion bacteria make their home in the average digestive system. Fortunately, less than one percent of the 400 different species found in the intestine are potentially harmful. The majority of intestinal flora are friendly bacteria, otherwise known as probiotics. These probiotic bacteria support good health by limiting the growth of harmful bacteria, promoting good digestion and increasing resistance to infection.*1

    Probiotic bacteria are completely non-toxic. In fact, friendly bacteria have been used safely and effectively for more than 8,000 years, proving their value to human health.*2  Most often, probiotics have been consumed as part of  cultured foods, such as acidophilus milk, yogurt, soy tempeh, and idli (cultured wheat). The friendly bacteria in these foods, specifically Lactobacillus acidophilus, L. bulgaricus, and Bifidobacterium bifidum, multiply in the warm, moist environment of the human body by feeding on the carbohydrates and protein in the digestive tract, then establish colonies along the intestinal wall.

    Beneficial Roles of Probiotics

    Lactobacillus acidophilus and other friendly bacteria play many important roles in maintaining good health.* According to experts, regular consumption of probiotics is the best way to maintain healthy intestinal flora.*3, 4 Lactobacilli species do not survive very long in the colon, so bacteria colonies need to be routinely replenished.*

    Healthy digestion:

    In addition to producing numerous vitamins, probiotics support healthy digestion.*  Part of the reason fermented foods are healthful is that some of the proteins, fats and carbohydrates are partially digested by the bacteria, which increases overall digestibility and nutritional value of the food.*5, 6

    Lactose intolerant individuals may gain even more benefits from probiotics. Lactobacilli bacteria ferment as much as half of the lactose in milk—the part of milk that results in the symptoms of bloating, cramps and gas in lactose intolerant individuals—by converting it to lactic acid. Consequently, people with lactose intolerance report fewer digestive problems with cultured dairy foods compared to fresh milk.*5, 7

    The nutritional profile of foods is improved after being cultured with probiotics. Levels of several B vitamins, including vitamins B1, B2, B6 and B12, niacin, folic acid and pantothenic acid are higher in fermented foods, such as yogurt, cheese, kefir and buttermilk.*5  Fermentation also boosts the digestibility of soy foods.*8

    Inhibiting bacterial growth:

    Probiotics act as natural antibiotics, slowing the growth of harmful bacteria.*5, 6 These friendly bacteria produce substances, including lactic acid, acetic acid, benzoic acid, hydrogen peroxide and natural antibiotics, which limit the reproduction of certain disease-causing bacteria.*9

    Another way that probiotic bacteria maintain a healthy digestive tract is by competing with harmful bacteria in the intestine. When the intestine is full of large colonies of beneficial bacteria, disease-causing bacteria are simply not able to multiply into harmful numbers because there are no available attachment sites on the intestinal wall.* This is one of the ways L. acidophilus inhibits the growth of Candida albicans, coliform (e. coli) bacteria and salmonella.*3, 4, 10, 11

    Diarrhea can have many causes, but it always has the same result for the bacteria living in the intestine—it flushes them out, leaving the body vulnerable to the growth of opportunistic bacteria. It is important to replenish the body with probiotics during and after a bout of diarrhea.* Probiotic bacteria can also help keep the colon healthy when traveling.*4

    Lactobacilli are one of the primary bacteria found in normal vaginal flora, and their presence is believed to inhibit the overgrowth of harmful bacteria, such as Candida. Lactobacillus acidophilus cultures are a popular folk remedy for vaginal health.*4, 10

    Recolonization After Antibiotic Use:

    Antibiotics, given to treat bacterial infections, ironically can contribute to unhealthy bacteria growth. Antibiotics destroy bacteria, the good along with the bad, leaving the intestine without its normal, healthful flora. In this compromised state, disease-causing bacteria can multiply unchecked by friendly bacteria.*12 When ingested during and following antibiotic usage, L. acidophilus rapidly restores normal flora, shortening the time that undesirable organisms remain in the gut.*3, 12 Bifidobacterium bifidum can also help normalize the intestinal flora after using antibiotics.*10  

    Producing the Best Probiotics

    Fermenting foods with lactobacilli has been a time-honored method for both preserving and enhancing foods.  Before refrigeration, fermentation was a valuable way to preserve food safety, and it remains in common usage today.

    Nature’s Life uses the same basic principles developed and perfected by prehistoric nomadic peoples to produce Lactobacillus acidophilus products; with the exception that we use modern, high-volume equipment. These improvements, along with trained personnel, scientific methods and quality assurance practices, ensures that every batch meets our high standards of quality.

    Our lactobacilli are cultured on nutrient-dense food concentrates, such as soy protein, green peas or non-fat milk. We add natural apple juice, pasteurized clover honey, strawberries, carrot juice or maltodextrin for flavor and to provide carbohydrates for the micro-organisms, plus we use only pasteurized water.

    Our growth medium has a broad range of vitamins, minerals, enzymes, amino acids, essential fatty acids, organic acids and naturally occurring plant phytonutrients such as flavonoids and carotenoids with beneficial antioxidant properties. The temperature and moisture are carefully controlled during the several days needed for the bacteria to multiply to peak potency.

    At the peak of potency, Nature’s Life Liquid Acidophilus culture is poured directly into sanitized 16 oz. glass bottles and immediately refrigerated at 36°F to maintain peak potency. These liquid products are the most bioactive of all forms of acidophilus because they are dormant, rather than frozen.

    For our freeze-dried powders and capsules, the warm liquid culture is immediately poured into containers, sealed and refrigerated. After cooling, the liquid is poured into trays and instantly freeze-dried. The frozen lactobacillus is then processed through a vacuum freezer to lower the moisture level to an absolute minimum. This freeze-dried product is packaged as either powder or capsules. When swallowed, the microorganisms will rehydrate and begin colonizing the gastrointestinal tract with friendly bacteria.

    Nature’s Life acidophilus is not filtered, centrifuged or otherwise concentrated or separated from its growth medium to artificially obtain higher concentrations of bacteria per gram or capsule. Centrifuging may damage the lactobacillus by altering the natural clumping, chaining and branching of bacteria cells.*

    Nature’s Life probiotic products retain all the benefits of the nutrient-rich growth medium. All the valuable by-products of the bacteria’s metabolism remain in the final product, including B-vitamins, enzymes, organic  acids, antibodies and even naturally occurring antibiotics. The conclusion of experts is that products which are centrifuged or filtered are incomplete.13 14

    Quality You Can Trust

    Nature’s Life invests significant resources in perfecting the production of high quality Lactobacillus acidophilus cultures. You benefit from our knowledge and experience every time you choose our supplements.

    Nature’s Life lactobacillus cultures are manufactured with rigorous specifications using state-of-the-art equipment. All equipment and containers are sanitized to ensure that no contaminants or unfriendly pathogenic bacteria corrupt the quality of the L. acidophilus. The large capacity fermentation tanks and freeze dryers maintain consistency in each batch.

    Nature’s Life Lactobacillus acidophilus meets or exceeds all standards developed by industry associations and government regulations. These standards, established to determine the quality of the finished product, are:

    • Identification of each species based on approved microbiology methods.

    • Confirmation of bacteria potency counts based on standardized testing methods.

    • The use of Good Manufacturing Practices to ensure each batch of product is consistently produced to standards.

    • Potency claims are made on the front panel and certified to be viable through a date printed on the side panel.

    All of Nature’s Life Lactobacillus acidophilus products meet the acid test for effectiveness:

    • Enough bacteria survive the high acidity of the stomach and retain their viability and effectiveness.

    • The organisms multiply rapidly in the intestine providing all the benefits of these friendly bacteria.

    • The bacteria effectively inhibit the growth of undesirable bacteria.

     

    Using Nature’s Life Probiotics

    Nature’s Life probiotics, such as Lactobacillus acidophilus, L. bulgaricus and Bifidobacterium bifidum, can survive in the stomach for at least an hour.*15 Nature’s Life recommends taking probiotics either on an empty stomach or with food, however the presence of food can help the organisms stay alive longer.16

     Liquid acidophilus should be treated as a perishable product, since it contains live, active organisms. Like yogurt or milk, acidophilus should be refrigerated and used within a short period of time. Contact Nature’s Life for a recipe on how to make your own soy-based, milk-free yogurt.

    References:

    1. Roberfroid MB, Bornet F, Bouley C, et al: Colonic microflora: Nutrition and Health.

    2. Rosell, J.M, Can Med Assoc J, 1932; 26:341.

    3. Alm, L. The effect of Lactobacillus acidophilus administration upon the survival of Salmonella in randomly selected human carriers. Prog Food Nutr Sci, 1983; 7:13-17.

    4. Hilton, E., et al. Ingestion of yogurt containing Lactobacillus acidophilus as prophylaxis for candidal vaginitis. Ann Int Med 1992;116:353-7.

    5. Friend, B.A. et al. Nutritional and therapeutic aspects of Lactobacilli. J of Appl Nutr, 1984; 36(2):125-153.

    6. Fernandes, C.F., et al. Therapeutic role of dietary Lactobacilli and Lactobacillus fermented dairy products. Fed of Eur Microbiol Rev, 1987; 46:343-356.

    7. Gorbach SL: Lactic acid bacteria and human health. Ann Med 1990;22:37-41.

    8. Hutchins AM, Slavin JL, and Lampe JW: Urinary isoflavonoid phytoestrogen and lignan excretion after consumption of fermented and unfermented soy products. J Am Diet Assoc 1995;95:545-551.

    9. Shahani, K.M., et al. Natural antibiotic activity of Lactobacillus acidophilus and bulgaricus, Cult Dairy Prod J, 1976; 11(4):14-7.

    10. Elmer GW, Surawicz CM, and McFarland LV: Biotherapeutic agents. A neglected modality for the treatment and prevention of selected intestinal and vaginal infections. (review) JAMA 1996;275(11):870-876.

    11. Prajapati, J., et al. Nutritional and therapeutic benefits of a blended spray-dried acidophilus preparation. Cult Dairy Prod J, 1986; 21(2):16-21.

    12. Fernandes, C.F., Shanhani, K.M., Amer, M.A., Control of diarrhea by Lactobacilli, J Appl Nutr, 1988; 40(1):32-43.

    13. Hansen, R., New starter cultures with 100-200 billion cells, North European Dairy J, 1980; 3:62:9.

    14. Klaenhammer, T.R., Microbiological considerations in selection and preparation of Lactobacillus strains for use as dietary adjuncts, J Dairy Sci, 1982; 65:1339-49.

    15. Kurmann, J.A., Rasic, J.L., The health potential of products containing bifidobacteria. Chapter 6 in: Properties of Fermented Milks, Elsevier Science Publishers, Barking, Essex, England, 1991.

    16. Petterson, L., et al, Survival of Lactobacillus acidophilus NCDO 1748 in the human gastrointestinal tract. XV Symposium, Swedish Nutrition Foundation, 1983.

    17. Fuller, R. Probiotics in man and animal. J Appl Bact, 1989; 66:365-78.

    18. Gilliland, S.E., and Speck, M.L., Instability of Lactobacillus acidophilus in yogurt. J Dairy Sci, 1977; 60:1394-98.

    19. Alm, L., The...effects of various cultures - an overview, Chapter 3 in: Properties of Fermented Milks, Elsevier Science Publishers, Barking, Essex, England, 1991.



    --
    Vitanet ®

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    Allergy & Sinus Season: Healthy Lifestyle Tips
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    Date: June 09, 2005 09:12 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Allergy & Sinus Season: Healthy Lifestyle Tips

    Source Naturals' Allergy and Sinus Lifestyle Plan

    Allergies are a growing health problem in the United States, according to a recent report issued by the American Academy of Allergy, Asthma, and Immunology (AAAI). Every year more than 50 million Americans suffer from allergies. They are the sixth leading cause of chronic disease and affect more than 20% of the population. Hay fever alone accounts for more than eight million doctor visits annually, at a cost of $3.4 billion!

    Source Naturals, as part of its commitment to Strategies for Wellness offers you these healthy lifestyle tips for allergy and sinus support.

    Allergy & Sinus Season: Healthy Lifestyle Tips

    Allergies are adverse reactions of the immune system to normally harmless substances?allergens. Some common allergens are pollen, weeds, molds, dust mites, animal dander, and latex particles.

    Allergens can enter the body through inhalation, ingestion, skin contact, or injection (either intentionally as in the case of certain medications or through insect stings). Although there is a strong genetic component to allergies, there are also lifestyle factors we can control to prevent or minimize allergic reactions. Allergies are actually 'mistakes' or overreactions by the immune system. They are learned responses, which can be unlearned.

    Allergy Proof Your Home

    Cut down your exposure to dust mites and other indoor allergens by dust proofing your bedroom. Eliminate wall-to-wall carpets, down-filled blankets, feather pillows, and other dust catchers. Use window shades instead of venetian blinds, which can trap dust. Wash curtains and bedding regularly in hot water. Encase your mattress and pillows in airtight, dust-proof plastic covers. Dust and vacuum regularly.

    If you have pets, especially cats, you should try to keep them out of your bedroom. Frequent brushing and bathing of pets can help get rid of excess hair.

    Consider using a HEPA (high-efficiency particulate air) filter system if you have allergies to pollen, dust, or other particles -- or if you live with a smoker, or in a smoggy urban area. Dehumidifiers can help cut down on molds.

    Avoid Outdoor Allergens

    You may need to limit your time outdoors when pollen or mold spore counts are high. Walking through uncut fields or raking leaves can increase exposure to molds and fungi. Avoid tobacco smoke and polluted air. Keep windows and doors closed, and dry clothes in a vented dryer instead of outside.

    Watch Your Diet

    Sometimes 'avoidance therapy' to control allergies is impractical or undesirable. Diet is easier to work with and can have a significant influence on immune reactions. Excess or undigested dietary proteins may worsen an overresponsive immune system?cows' milk and wheat are frequent offenders. Cut down on protein, especially animal protein, avoid dairy products, and eat more fruits, vegetables, and complex carbohydrates. You should also avoid nutritionless foods such as simple sugars.

    Maintain Healthy Mucous Membranes

    The mucosal cells that line the nasal passages, throat and lungs are our first line of defense against airborne substances. One of the primary means of maintaining healthy mucous linings is to drink lots of pure water (6 to 8 glasses daily). This keeps mucus fluid thin and cleanses membranes. Nasal cleansing is helpful when sinuses are clogged. You can rinse the nasal passages with a warm solution consisting of a quarter-teaspoon of salt to a cup of warm water, about the same sodium concentration found in your blood and tissue fluids. This practice washes away pollen grains and soothes irritated mucous membranes. Nasal cleansing can be done using a rubber suction bulb or a neti pot?a ceramic container used in Ayurveda that allows you to pour water directly into the nose. Inhaling steam with a little oil of eucalyptus in it may also ease clogged sinuses. Many people find acupuncture to be very effective for promoting sinus drainage.

    Supplementation

    Nutrients and herbs offer you safe, natural alternatives for supporting seasonal health. The bioflavonoid quercetin has been found in human cell culture studies to inhibit the release of histamines from immune cells. Ginkgo has been found in human cell culture studies to inhibit platelet-activating factor, a substance that stimulates the release of histamines. (Research is needed to determine if these effects occur in humans.) Stinging nettle is another herb that has been used traditionally to support a healthy respiratory system and sinuses. Vitamin A enhances macrophage function, is specifically needed for a healthy lung lining, and is beneficial for increasing the health of tissue cell membranes.



    --
    VitaNet ®
    VitaNet ® Staff

    Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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    Chem-Defense - Fight Chemical sensitivity ...
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    Date: June 01, 2005 10:21 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Chem-Defense - Fight Chemical sensitivity ...

    Chem Defense

    CHEMICAL SENSITIVITY IS REAL.

    COURTESY OF THE INDUSTRIAL REVOLUTION, OUR ENVIRONMENT HAS BECOME A STEW OF FOREIGN CHEMICALS. For some people suffering the malaise, lack of focus, and drained feeling associated with chemical sensitivities, home is the only sanctuary from this onslaught. For others, not even home is safe. We at Source Naturals take this threat very seriously. That’s why we created CHEM-DEFENSE.

    Source Naturals’ CHEM-DEFENSE is a potent combination of Molybdenum, Glutathione, and Coenzymated B-2, nutrients which research has shown may help break down and dispel harmful chemicals from the body. And CHEM-DEFENSE is sublingual — it dissolves under the tongue so it goes directly into your bloodstream, where it can be delivered to your system, fast.

    major problem has hit America in the late 20th century that is more far reaching than most people are aware — chemical sensitivity. In fact, some studies indicate that 1 out of 3 Americans may be afflicted with chemical sensitivities. In the past century, modern organic chemistry has synthesized and released into the world an estimated 300,000 xenobiotic (foreign to our normal biology) chemicals. The food processing and food growing industries put an approximate 10,000 xenobiotic chemicals into our food supply alone. These chemicals can be found in common items such as cleaning fluids, drycleaning compounds, glues, cigarette smoke, perfume, building materials and processed foods. Chemical sensitivity is the result of impairment or inadequacy of the body’s natural detoxification systems, allowing excessive levels of harmful, xenobiotic chemicals to accumulate in the body, and the results are often devastating. In sensitive people, artificial chemicals can cause an incredible range of problems: “fogginess” and lack of focus, emotional distress, fatigue, and more. The parts of the body that are most affected can vary from person to person. Some of the worst offenders are the aldehydes. The most infamous of these is formaldehyde (found in such widely used items as permanent press clothing, particle board, paints and upholsteries). The other common culprit is acetaldehyde (produced by Candida overgrowth or from alcohol consumption).

    The Secret to CHEM-DEFENSE’S Power is Molybdenum

    Fortunately, nature has provided the body with a special aldehyde detoxification pathway: an enzyme called aldehyde oxidase (ADO). ADO is activated by one of the coenzyme forms of Vitamin B2, Flavin Adenine Dinucleotide (FAD), and the trace mineral Molybdenum. Unfortunately, this enzymatic pathway can become impaired due to overexposure to foreign chemicals. In addition, aging, nutritional deficiencies, genetics and general poor health can greatly diminish the body’s production of these enzymes, causing a toxic buildup of aldehydes, leaving many individuals vulnerable. Current nutritional research has revealed that supplementing the diet with Molybdenum and Coenzyme B-2, both found in CHEM-DEFENSE, can increase levels of the important enzyme ADO, helping to dispel toxins from the body. A study published in the Townsend Letter for Doctors confirms the benefits of a sublingually administered 300 mcg dose (100 mcg three times a day) of Molybdenum. It was found that on the average, about 50-65% of the various symptoms of chemical sensitivity — including fogginess and other discomforts — were alleviated at least to some degree. Molybdenum is also important for several other enzymes, including xanthine oxidase, and most importantly, sulfite oxidase. Sulfite oxidase is responsible for breaking down sulfites, chemicals widely used as preservatives in wines, salad bars, produce, and other foods. Sulfites are a common culprit in chemical sensitivity reactions. In fact, by the 1980’s, it was conservatively estimated that 5,000,000 (five million) Americans were sensitive to sulfites and experienced discomfort upon ingestion. Sulfite oxidase is also important in the sulfation of various compounds, especially in the brain. This is particularly important, as the brain is often dramatically affected during bouts of chemical sensitivity. According to the Nutrition Desk Reference, the amount of Molybdenum required daily for people is 100 mcg to 500 mcg. It also states that the amount of Molybdenum in food can vary tremendously, depending on crop soil levels. Low levels are not at all uncommon, and they are lessened even further by commercial farming practices that utilize synthetic fertilizers which do not put Molybdenum back into the soil. The result? The typical American diet does not provide adequate Molybdenum. The form of Molybdenum included in CHEM-DEFENSE is Molybdenum Aspartate-Citrate, Molybdenum bound to the cellular metabolites Aspartic Acid and Citric Acid. This has been shown to be the most bioactive form available by experts in mineral metabolism.

    Glutathione in its Most Bioavailable Form

    Ultimately, the one organ that must cope with and attempt to relieve the body of toxic chemicals is the liver, often referred to by nutritionists as “the body’s most overburdened organ.” To accomplish this, the liver must rely heavily on Glutathione, a tripeptide (three amino acids bound together). The Glutathione in CHEM-DEFENSE will help the liver to produce adequate levels of the important enzymes glutathione peroxidase (GSHpx) and glutathione S-transferase (GSH-S), enzymes that are essential for breaking down and disposing of foreign chemicals in the body. Glutathione peroxidase (GSHpx) helps to break down hydrogen peroxide, a medium-level toxin which is found in many xenobiotic chemicals. GSHpx also prevents cell damage caused by fatty acid oxidation, which threatens the integrity of cell membranes. Glutathione is very fragile. In fact, when taken orally, it is often destroyed by protein-digesting enzymes in the stomach. As CHEM-DEFENSE is in sublingual form, it bypasses the digestive process and goes straight into the bloodstream, allowing for maximum activity.

    Coenzyme B2 — The “Recycling” Nutrient

    Once Glutathione is used in the body for its detoxification functions, it becomes oxidized Glutathione, meaning it has been “used up.” Fortunately, the human body can “recycle” oxidized Glutathione and return it to its beneficial reduced (active) state. This process is made possible by a coenzyme form of Vitamin B2 (FAD), which is present in CHEM-DEFENSE.

    Sublingual Delivery for Maximum Benefit

    Many nutrients, when taken orally, are never completely absorbed into the bloodstream, or not absorbed at all! Because this formula is in sublingual form, the nutrients in CHEM-DEFENSE are absorbed directly into the bloodstream through the blood vessels under the tongue and in the cheeks, assuring maximum bioavailability and benefit. In America today, as foreign chemicals continue to be released into the environment on an uncontrolled basis, people continue to experience chemical sensitivities for which there appears to be no solution. Now there is. Source Naturals CHEM-DEFENSE combines the most bioavailable forms of key antioxidant nutrients that are not only powerful in and of themselves, but work together synergistically to address the problems associated with chemical sensitivities. As with all of their other products, Source Naturals has taken special care to create a product that is all natural, hypo-allergenic, and sugarfree. CHEM-DEFENSE sublingual is available in two delicious flavors — natural peppermint, and for people on homeopathic regimens who prefer an alternative to peppermint, natural orange flavor. Let’s face it — life in the modern world is a battle for your health. Arm yourself with a powerful weapon: Source Naturals CHEM-DEFENSE.

    References
    1. Arias, I.M. et al. The Liver — Biology and Pathobiology. ©1988 by Raven Press: New York, N.Y.
    2. Garrison, R.H. & Somer, E. The Nutrition Desk Reference © 1985 by Keats Publishing: New Canaan, C.T.
    3. Shils, Maurice E & Young, Vernon R. (1988). Modern Nutrition in Health and Disease © 1988 by Lea & Febiger: Philadelphia, PA.
    4. Cooter, Stephen, Ph.D. Molybdenum: Recycling Fatigue Into Energy. Townsend Letter for Doctors. (April, 1994): 332-36



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    Under-Reported (and Underappreciated) Cholesterol control.
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    Date: May 12, 2005 10:00 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Under-Reported (and Underappreciated) Cholesterol control.

    Under-Reported (and Underappreciated) Solutions for Cholesterol and Triglyceride Control

    by Richard Conant, L.Ac., C.N.

    Fat and human existence are inseparable. Setting aside the fear and loathing over fat in the body that pervades our culture, we understand that fat is our friend. We cannot live without fat.

    The human body contains many different kinds of fats and fat-like molecules. Collectively known as "lipids" these fatty substances include fatty acids, lipoproteins, phospholipids, glycolipids, triglycerides, steroid hormones and the infamous, dreaded cholesterol.

    Lipids (fats) are found everywhere in the body, performing a variety of vital functions. The brain is a fat-rich organ. Brain neurons and all other nerve cells are protected by a myelin sheath, made largely out of fatty material. Cell membranes consist almost entirely of phospholipids (lipids that contain phosphorus) arranged in a sandwich-like double layer embedded with proteins. Sex hormones are lipids, belonging to the group of complex lipid molecules known as "steroids." Vitamin D is a lipid.

    The body stores and transports fatty acids in the form of triglycerides. A triglyceride contains three fatty acid molecules, which have a chain-like structure, linked to glycerol. (There are also mono- and di-glycerides, which have one and two fatty acid chains, respectively, attached to glycerol.)

    Like many other things necessary to life, fat is a two-edged sword. Fat insulates us from the cold, cushions and protects our vital organs and serves as a storehouse for energy. Yet, when present in excess to the point of obesity, fat threatens health, happiness, self-esteem, social standing and longevity. The same is true of other lipids, most notably triglycerides and cholesterol. Transported throughout the body in the bloodstream, these essential lipids become a health liability when the blood contains too much of them.

    Keeping fat in it its proper place, not eliminating or drastically reducing it, is the goal we should seek. In the blood, lipids must be maintained at healthy levels and ratios. When they are, an important foundation of good health is established.

    How do we keep the blood lipids we need——triglycerides and the various forms of cholesterol——balanced at healthy levels? Diet and exercise are indispensable, these basics must come first. Along with the recommended dietary practices, a number of nutritional approaches offer help for maintaining healthy blood lipids. We will now give several of these a closer look.

    Gugulipid

    In 1990, an herb used for centuries in the Far East was introduced to U.S. consumers. This herb, called "gum guggul," is proving to be one of the most effective natural cholesterol-lowering agents ever discovered. It also brings triglycerides down and raises HDL, the "good" cholesterol. The changes are substantial; gum guggul single-handedly normalizes the entire blood lipid profile, even in people with high starting levels of cholesterol and triglycerides.

    Gum guggul, also called simply "guggul," is a gummy resin tapped from the Commiphora tree. A cousin of myrrh gum, guggul has been used by Ayurvedic herbalists of India for at least 3,000 years; texts dating from around 1,000 B.C. mention the herb. Guggul was traditionally given for rheumatism and poor health caused by excess consumption of fatty foods. One ancient Sanskrit text describes in detail what happens in the body when blood fats are out of balance, due to sedentary lifestyle and overeating. The name of this condition has been translated as "coating and obstruction of channels."

    Intrigued by the obvious similarity between "coating and obstruction of channels" and arteries clogged by fatty plaque, Indian researchers initiated a series of experimental and clinical studies in the 1960's to see if gum guggul would lower excess blood lipids.1 Both human and animal studies consistently showed cholesterol and triglyceride reductions.

    Detailed pharmacological studies showed that guggul's lipid-lowering effects are produced by compounds in the resin called "guggulsterones."2 An Indian pharmaceutical firm then patented a standardized extract of gum guggul under the trade name "Gugulipid." The product contains a uniform 2.5 percent guggulsterones, which is higher than guggul resin in its natural state.

    Because Gugulipid guarantees the necessary intake of guggulsterones needed for blood fat reduction, it has become the product used in clinical research. Phase I efficacy safety trials and Phase II efficacy trials have yielded more positive data.3,4,5 Most of the studies on gum guggul have used relatively small numbers of subjects; this tends to make mainstream medical scientists reluctant about natural remedies. A large, well-publicized double-blind Gugulipid trial on 400 to 500 people would go a long way toward giving this herb the credibility it deserves.

    Pantethine

    Another effective natural solution for blood fat control that should be better known is a relative of pantothenic acid (vitamin B5). Pantethine is the active form of pantothenic acid in the body. Pantethine forms CoA, an essential co-enzyme for utilization of fat. CoA transports "active acetate," an important byproduct of fat metabolism that provides fuel for generating cellular energy. By promoting the burning of fats for energy, pantethine helps keep triglyceride levels down.6 Pantethine also helps regulate cholesterol production, by facilitating the conversion of fat into other lipid-based molecules needed in the body.6

    Japanese researchers began studying the effect of pantethine on blood fats nearly twenty years ago. They reported their promising results at the Seventh International Symposium on Drugs Affecting Lipid Metabolism, held in Milan, Italy in 1980.7 Few in the medical or scientific communities took notice. Italian researchers followed up with several small clinical trials that confirmed the preliminary reports.6,8,9 An excellent cholesterol and triglyceride lowering agent that is safe and free of side-effects, pantethine remains, for the most part, ignored by mainstream science, although its usage is growing in alternative medicine circles. Pantethine it will no doubt prove to be one of the most important supplements for maintaining healthy blood fat levels.

    Niacin

    When taken in high enough doses, niacin (vitamin B3) substantially lowers cholesterol. This has been known to medical science for many years.10 studies on niacin as a cholesterol-lowering agent go back to the 1950's. There was a fair amount of initial enthusiasm for niacin because it improves, unlike most lipid-lowering drugs, all parameters of the blood lipid profile. Niacin reduces total cholesterol, LDL cholesterol and triglycerides. It also raises HDL cholesterol quite well. Interest in niacin has faded, in part because the necessary dose, 1200 milligrams a day or more, can cause flushing and gastrointestinal disturbances. Very high doses may be harmful to the liver if taken for too long.

    There is a solution to the side-effect problem with niacin which, again, has failed to gain widespread attention. Inositol hexanicotinate is a flush-free form of niacin composed of six niacin molecules bonded to one molecule of inositol, another B-complex nutrient. Absorbed as an intact structure, inositol hexanicotinate is metabolized slowly, releasing free niacin into the bloodstream over a period of hours following ingestion.11 Inositol hexanicotinate has all the benefits of niacin for controlling blood fats. The flushing effect of ordinary niacin, which metabolizes much more rapidly, does not occur. Taking as much as four grams per day has not been reported to raise liver enzymes or cause other side-effects, but prudence dictates that people with liver problems should avoid very high doses of inositol hexanicotinate, or any form of niacin.12

    Tocotrienols

    We often think of vitamin E as synonymous with d-alpha tocopherol. Vitamin E is actually a whole family of compounds that includes various tocopherols and a group of lesser known but highly beneficial substances called "tocotrienols." All have vitamin E activity. Tocotrienols are similar in chemical structure to tocopherols, but they have important differences which give them unique and highly beneficial properties for human health.

    Vitamin E is one of the most recognized antioxidants, nutrients that deactivate potentially toxic byproducts of oxygen metabolism known as free radicals. Vitamin E neutralizes peroxides, which result from the free radical oxidation of lipids, making it a key antioxidant in cell membranes. While d-alpha tocopherol has generally been regarded as the form of vitamin E with the strongest antioxidant activity, tocotrienols are even stronger.

    The tocotrienol story is another example of a natural product slow to gain recognition. A Univeristy of California research team discovered that d-alpha tocotrienol is over six times more effective than d-alpha tocopherol at protecting cell membranes against free radical damage.13 In the presence of vitamin C, which recycles vitamin E-like compounds, its antioxidant activity is 40 to 60 times higher than d-alpha tocopherol. This study was published in 1991. Its safe to say few cardiac physicians know about tocotrienols, and we have yet to see 60 Minutes do a piece on "the powerful new form of vitamin E."

    It would be a tremendous service to public health if they did, because the benefits of tocotrienols go far beyond their stellar antioxidant ability. Tocotrienols also lower total cholesterol and LDL, by impressive percentages. In one double-blind controlled study, tocotrienols reduced total cholesterol by 16 percent and LDL by 21 percent after twelve weeks. Another study recorded drops of 15 to 22 percent in total cholesterol along with 10 to 20 percent decreases in LDL levels.14 Now appearing on health food store shelves, tocotrienols are a health-protecting nutrients whose long overdue time has come. Derived from food oils such as palm oil and rice bran oil, tocotrienols have the same lack of toxicity as ordinary vitamin E.

    References

    1. Satyavati, G. Gugulipid: a promising hypolipidaemic agent from gum guggul (Commiphora wightii). Economic and Medicinal Plant Research 1991;5:47-82.

    2. Dev, S. A modern look at an age-old Ayurvedic drug—guggulu. Science Age July 1987:13-18.

    3. Nityanand, S., Srivastava, J.S., Asthana, O.P. Clinical trials with gugulipid. J. Ass. Physicians of India 1989;37(5):323-28.

    4. Agarwal, R.C. et. al. Clinical trial of gugulipid—a new hypolipidemic agent of plant origin in primary hyperlipidemia. Indian J Med Res 1986;84:626-34.

    5. 'Gugulipid' Drugs of the Future 1988;13(7):618-619.

    6. Maggi, G.C., Donati, C., Criscuoli, G. Pantethine: A physiological lipomodulating agent, in the treatment of hyperlipidemias. Current Therapeutic Research 1982;32(3):380-86.

    7. Kimura, S., Furukawa, Y., Wakasugi, J. Effects of pantethine on the serum lipoprotiens in rats fed a high cholesterol diet (Abstract) Seventh International Symposium on Drugs Affecting Lipid Metabolism, Milan, Italy, 1980.

    8. Arsenio, L. Bodria, P. Effectiveness of long-term treatment with pantethine in patients with dyslipidemia. Clinical Therapeutics 1986;8(5):537-45.

    9. Avogaro, P. Bittolo Bon, G. Fusello, M. Effect of pantethine on lipids, lipoproteins and apolipoproteins in man. Current Therapeutic Research 1983;33(3):488-93.

    10. Crouse, J.R. New developments in the use of niacin for treatment of hyperlipidemia: new considerations in the use of an old drug. Coronary Artery Disease 1996;7(4):321-26.

    11. Welsh, A.L. Ede, M. Inositol hexanicotinate for improved nicotinic acid therapy. International Record of Food Medicine 1961;174(1):9-15.

    12. "Inositol hexaniacinate" (Monograph). Alternative Medicine Review 1998;3(3):222-3.

    13. Serbinova, E., et. al. Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha tocotrienol. Free Radical Biology and Medicine 1991;10:263-275.

    14. Qureshi, N. Qureshi, A.A. Tocotrienols: Novel Hypercholesterolemic Agents with Antioxidant Properties. in 'Vitamin E in Health and Disease' Lester Packer and Jürgen Fuchs, Editors. 1993; New York: Marcel Dekker, Inc.

    Control Cholesterol with the following Supplements

  • Policosanol -- Reduces Production of Cholesterol by the Liver
  • Red Yeast Rice -- Reduces production of cholesterol like pharmaceutical Statins on the market today
  • Sytrinol -- Lowers Cholesterol by reducing production of cholesterol in the body like Statins on the market today
  • Fiber -- Helps elimate waste and reduce cholesterol


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