NOW: D-MANNOSE 500MG 120 Caps

D-MANNOSE 500MG - 120 Caps



by   NOW FOODS
*MSRP:
$31.99
Our Price:
$18.56
Buy: at $18.56
(3 for $ 18.55ea. = $ 55.65 ) 42% OFF MSRP
UPC: 733739028112
# N2811

NOW D-Mannose 500 mg Veg Capsules

Natural Bladder Cleansing and Urinary Tract Support

NOW Foods D-Mannose 500 mg is a pure, gentle supplement designed to cleanse the bladder and keep your urinary tract healthy and comfortable[cite: 1]. D-mannose is a simple, naturally occurring sugar with the chemical formula C6H12O6. Unlike common table sugar, your body does not easily burn D-mannose for fuel; instead, it travels through your bloodstream directly to your kidneys and bladder, where it attaches to unwanted particles so they can be naturally flushed away with your normal urine flow [1, 3].

Quick Specs Snapshot

  • ✓ Active Form & Potency: Delivers 1.5 grams (1,500 mg) of pure, unadulterated D-mannose per 3 vegetarian capsules (500 mg per capsule).
  • ✓ Primary Cellular Target: Bladder lining (mucosa) and urinary tract epithelial cells.
  • ✓ Supply & Value Math: 120 vegetarian capsules provide a complete 40-day supply (at 3 capsules daily) for just pennies per serving.
  • ✓ Formulation Purity: Non-GMO, vegan, gluten-free, soy-free, and packaged in a 100% post-consumer recycled (PCR) resin bottle.

Buyer's Guide & Form Comparison

Why the Form Matters

Many people turn to cranberry juice or cranberry pills when they want urinary tract support, but cranberry products can be acidic on the stomach and often contain excess sugar [2]. Pure D-mannose works completely differently. Because it is the exact simple sugar that foreign micro-organisms bind to, it acts directly in the bladder without upsetting your stomach acid or spiking your normal blood sugar levels [1, 2]. While cheap discount store brands frequently use weak dilutions or low-grade fillers, NOW Foods uses pure, lab-tested D-mannose that gives you consistent, reliable strength in every single capsule[cite: 1].

Is This Formula Right for You?

Ideal For Shoppers Who:

  • ✓ Want a proven, natural way to cleanse the bladder and support long-term urinary comfort [1, cite: 1].
  • ✓ Prefer clean, pre-measured vegetarian capsules over tart juices or messy powders.
  • ✓ Are looking for effective urinary tract care that will not disrupt their regular diet or healthy carbohydrate balance [3].

Consider Another Option If:

  • ✗ You prefer dissolving a loose bulk powder directly into water or morning smoothies.
  • ✗ You struggle with swallowing standard capsules and require a liquid drop format.
  • ✗ You are experiencing severe symptoms such as kidney pain or fever, which require immediate evaluation by a licensed healthcare provider.

Risk-Free Assurance: Every order is backed by VitaNet®, LLC's unconditional 100% money-back guarantee—even on opened bottles, with return shipping covered—allowing you to evaluate your personal comfort completely risk-free[cite: 1].

How D-Mannose Works at the Cellular Level

To understand how D-mannose cleanses your bladder, picture the cells lining your urinary tract as smooth walls covered in tiny natural sugars. Common nuisance bacteria, especially Escherichia coli, have tiny hair-like fingers called fimbriae or lectins. Think of these fingers like little pieces of velcro that search for sugars on your bladder wall so they can latch on and multiply [1, 2].

When you take NOW D-Mannose, its molecular structure (C6H12O6) bypasses normal digestive breakdown [1, 3]. Because your liver does not convert large amounts of it into energy or store it as glycogen, over 90% of the D-mannose you swallow enters your bloodstream intact within 30 to 60 minutes [3]. Your kidneys immediately filter it out of your blood and empty it into your bladder reservoir [1, 3].

Once inside the bladder, D-mannose acts like a clever decoy. The bacteria's velcro-like fingers are far more attracted to the free-floating D-mannose in your urine than to your bladder wall [1, 2]. They lock onto the D-mannose molecules instead. Once the bacteria are stuck to the D-mannose, they cannot hold onto the bladder lining, and your body easily flushes them out every time you urinate [1, 4].

Daily Usage, Timing, and Synergy Protocol

Optimal Timing & Meal Pairing

Take 3 capsules 1 to 3 times daily with a full 8-ounce glass of pure water. D-mannose can be taken with or without food. Drinking plenty of water is the most critical step because fluids create the physical urine flow required to wash the D-mannose and trapped particles completely out of your system [3].

Daily Routine & Split Dosing

For general daily maintenance, take 3 capsules once per day in the morning. If you are seeking extra support, split your intake throughout the day (for instance, 1 capsule with breakfast, 1 with lunch, and 1 at bedtime). Splitting your doses keeps a fresh, steady supply of D-mannose circulating through your bladder both during the day and overnight while you sleep.

Smart Synergies & Spacing Rules

  • ✓ Great Pairs: Works exceptionally well alongside daily probiotic supplements (especially Lactobacillus strains) to support healthy microflora, and targeted cranberry extracts for dual-action urinary protection [4].
  • ✗ What to Avoid: Avoid taking D-mannose with sugary sodas or high-sugar fruit juices, as excess simple sugars can disrupt urinary tract balance. Stick to pure drinking water.

Timeline of Expectations

  • Week 1: D-mannose begins filtering through your kidneys into your urine within an hour of your very first serving, initiating rapid cleansing action [3].
  • Weeks 3–4: Regular daily use helps maintain a smooth, clean bladder environment and promotes steady day-to-day comfort.
  • Months 2–3+: Cumulative cellular protection helps keep your urinary tract balanced and resilient over the long term [1, 4].

Capsule Profile, Clean Ingredients & Laboratory Testing

Delivery Format & Swallowability

NOW D-Mannose comes in clear, standard two-piece vegetable capsules. They are lightweight, smooth, and simple to swallow with a standard glass of water.

Natural Aroma, Taste & Color

The encapsulated powder is white to off-white and has almost no scent. If you open a capsule, D-mannose powder has a mild, clean, slightly sweet taste (about half as sweet as table sugar) with no bitter aftertaste. Slight natural color variations between batches are normal and do not affect potency.

Other Ingredients Explained in Plain English

  • Hypromellose (cellulose capsule): A plant-based capsule shell made from natural wood pulp that dissolves quickly in your digestive system.
  • Rice Flour: A gentle, hypoallergenic grain powder used to evenly fill the capsule space.
  • Stearic Acid (vegetable source): A natural plant fat that lubricates processing machinery to keep powders moving cleanly.
  • Magnesium Stearate (vegetable source): A plant-derived mineral salt that ensures every capsule receives an identical, uniform dose.
  • Silicon Dioxide: A safe, natural compound derived from the earth that absorbs trace moisture to prevent the powder from caking.

Storage & Freshness

Store the bottle in a cool, dry place after opening. Keep the lid sealed tightly and avoid humid areas like medicine cabinets inside bathrooms to preserve full freshness.

NOW Brand Laboratory Testing & Contaminant Constraints

NOW Foods operates one of the most advanced, privately owned supplement testing facilities in North America, featuring state-of-the-art laboratories certified under ISO/IEC 17025 standards. Their analytical scientists conduct more than 19,000 separate tests every single month to guarantee purity from the raw ingredient stage to the finished bottle:

  • ✓ Identity Verification: Every incoming lot of D-mannose is tested using Fourier-Transform Infrared Spectroscopy (FTIR) and High-Performance Liquid Chromatography (HPLC) to verify true molecular identity and screen out adulterants.
  • ✓ Strict Heavy Metal Limits: Raw materials are screened using Inductively Coupled Plasma Mass Spectrometry (ICP-MS) down to parts-per-billion limits for lead, arsenic, cadmium, and mercury, ensuring compliance with strict safety standards.
  • ✓ Microbiological Defense: Tested for E. coli, Salmonella, yeast, mold, and total aerobic bacteria to confirm total microbial safety.
  • ✓ Allergen Security: Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, tree nut, or sesame ingredients, and packaged in bottles made from 100% post-consumer recycled resin.

Supplement Facts & Retailer Verification

Supplement Facts
Serving Size: 3 Veg Capsules  |  Servings Per Container: 40
Description Amount per Serving % Daily Value
Calories 10 †
Total Carbohydrate 2 g 1%**
Total Sugars 2 g †
D-Mannose 1.5 g (1,500 mg) †

** Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value not established.

Other Ingredients: Hypromellose (cellulose capsule), Rice Flour, Stearic Acid (vegetable source), Magnesium Stearate (vegetable source) and Silicon Dioxide.

Curator's Quality Note

Curated by the nutritional team at VitaNet®, LLC—an independent, family-owned American retailer providing premium vitamins and nutritional supplements online since 1995[cite: 1]. With over 31 years of direct experience evaluating supplement biochemistry and testing documentation[cite: 1], we proudly stand behind NOW Foods for their exceptional cGMP manufacturing practices, independent testing standards, and clean-label integrity[cite: 1].

Scientific References

  1. Kranjčec, B., Papeš, D., & Altarac, S. (2014). D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial. World Journal of Urology, 32(1), 79-84.
  2. Altarac, S., & Papeš, D. (2014). Use of d-mannose in prophylaxis of recurrent urinary tract infections (UTIs) in women. BJU International, 113(1), 9-10.
  3. Alton, G., Kjaergaard, S., Etchison, J. R., Skovby, F., & Freeze, H. H. (1998). Oral ingestion of mannose elevates blood mannose levels: a first step toward its use in carbohydrate-deficient glycoprotein syndrome type I. The Journal of Pediatrics, 133(1), 78-80.
  4. Domenici, L., Monti, M., Bracchi, C., Giorgini, M., Colagiovanni, V., Muzii, L., & Benedetti Panici, P. (2016). D-mannose: a promising support for acute urinary tract infections in women. A pilot study. European Review for Medical and Pharmacological Sciences, 20(13), 2920-2925.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Frequently Asked Questions

1. Will D-Mannose raise my blood sugar levels?

Even though D-mannose is chemically classified as a simple sugar (C6H12O6), very little of it is converted into energy or glucose by your body [1, 3]. It passes through your bloodstream and is quickly filtered into your urine by your kidneys, so it will not cause significant spikes in blood sugar when used as directed [1, 3].

2. Can I pull the capsules apart and stir the powder into a beverage?

Yes. The vegetable capsules can be easily separated, and the pure white D-mannose powder can be stirred directly into cold water or unsweetened juice. It dissolves quickly and has a mild, clean, lightly sweet taste.

3. How is D-Mannose different from cranberry supplements?

Cranberry contains compounds that support the bladder lining, but cranberry juices and tablets can be acidic and often contain unwanted sugars [2]. D-mannose acts as an exact physical decoy that attracts nuisance bacteria so they can be carried away in your urine, making it a targeted, gentle option for bladder cleansing [1, 2].

4. Will taking NOW D-Mannose break an intermittent fast?

A full 3-capsule serving contains only 10 calories and 2 grams of carbohydrates. Because your body excretes the vast majority of D-mannose through your urine rather than burning it for fuel, it will not trigger a meaningful metabolic shift or interrupt standard fasting routines.

5. How much water should I drink with each serving?

Always drink a full 8-ounce glass of water with each 3-capsule serving, and continue drinking water throughout the day. While D-mannose detaches unwanted particles from your bladder wall, plenty of fluids are needed to create the urine flow that carries them out of your body [3].

Helpful Customer Reviews



Supplemental Information