UPC: 733739032676
# N3267

NOW Pycnogenol® 100 mg (60 Veg Capsules)

Standardized French Maritime Pine Bark Extract (Pinus pinaster) Fortified with 240 mg Amla Fruit Extract

Clinically Studied Antioxidant & Endothelial Circulation Support

NOW® Pycnogenol® 100 mg supplies an evidence-based concentration of patented French maritime pine bark extract, one of nature's most extensively researched botanical compounds. Derived exclusively from sustainably managed pine forests along the southwestern coast of France (Les Landes de Gascogne), Pycnogenol® provides a standardized, bioavailable blend of water-soluble proanthocyanidins, bioflavonoids, and organic phenolic acids. Unlike standard pine bark extracts, genuine Pycnogenol® is backed by more than 40 years of scientific research, 160 clinical trials, and over 450 published studies validating its ability to protect cell structures from oxidative stress, encourage normal nitric oxide production, and support comprehensive vascular and microcirculatory health.

Evidence-Based Mechanisms & Physiological Benefits

1. Vascular Function & Microcirculation Support

Pycnogenol® enhances endothelial nitric oxide synthase (eNOS), the key enzyme responsible for producing nitric oxide (NO) within vascular linings. Optimal nitric oxide levels promote endothelial relaxation, supporting healthy blood vessel dilation, smooth venous blood flow, healthy blood pressure already within a normal range, and microcirculation to the extremities, eyes, and brain.

2. Collagen Synthesis & Joint Tissue Maintenance

Procyanidins selectively bind to collagen and elastin fibers, shielding connective tissues from enzymatic degradation caused by matrix metalloproteinases (MMPs) and elastase. This mechanism helps preserve cartilage matrix integrity, promotes comfortable joint mobility, and maintains structural support across delicate joint, skin, and vascular tissues.

3. Dermatological Health & Skin Elasticity

By promoting hyaluronic acid and collagen synthesis while neutralizing free radicals generated by environmental exposure and UV stress, Pycnogenol® supports dermal hydration, skin elasticity, and a smoother skin appearance from within.

4. Synergistic Antioxidant Matrix with Amla Extract

Each serving is fortified with 240 mg of Amla Extract (Phyllanthus emblica), also known as Indian Gooseberry. Amla is revered in traditional Ayurvedic wellness for its potent polyphenols, tannins, and naturally occurring vitamin C co-factors, creating a broad-spectrum antioxidant barrier against metabolic oxidative stress.

Why Genuine Pycnogenol® Outperforms Generic Pine Bark Extract

Many generic antioxidant supplements list unbranded "pine bark extract" (often from Chinese or generic maritime sources) or grape seed extract. While grape seed contains oligomeric proanthocyanidins (OPCs), Pycnogenol® possesses a unique molecular fingerprint:

Complete Supplement Facts & Clean Ingredient Profile

Supplement Facts Serving Size: 1 Veg Capsule | Servings Per Container: 60
Ingredient Amount Per Serving % Daily Value
Pycnogenol® (French Maritime Pine Bark Extract, Pinus pinaster) 100 mg *
Amla Extract (Fruit) (Phyllanthus emblica) 240 mg *
* Daily Value not established.
Other Ingredients: Hypromellose (cellulose capsule), Cellulose Powder, Stearic Acid (vegetable source), and Silicon Dioxide. Allergen & Dietary Information: Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, or tree nut ingredients. Produced in a certified GMP (Good Manufacturing Practices) facility that processes other ingredients containing these allergens. Purity Attributes: Vegan / Vegetarian, Non-GMO Project Verified, Kosher Certified, Halal, Soy-Free, Gluten-Free.

Suggested Usage, Dosage, and Medical Safety Guidelines

Suggested Protocol: Take 1 veg capsule 1 to 2 times daily, preferably with a meal containing healthy dietary fats to optimize botanical assimilation, or as directed by your qualified healthcare practitioner.

Important Clinical Precautions & Interactions

For adults only. Consult your physician prior to taking this or any dietary supplement if you: Keep out of reach of children. Do not eat the enclosed freshness packet; retain in original bottle. Store in a cool, dry place after opening.

Why Purchase NOW® Pycnogenol from VitaNet®, LLC?

Frequently Asked Questions (FAQ)

What is the primary difference between Pycnogenol 100 mg and 60 mg?

A 100 mg dosage reflects the standard clinical therapeutic threshold utilized in peer-reviewed human trials evaluating vascular stiffness, leg circulation, and joint discomfort. While 60 mg provides maintenance antioxidant defense, 100 mg (combined here with 240 mg Amla) provides a more potent single-capsule serving for targeted cardiovascular, skin, and microcirculatory objectives.

How quickly can I expect to notice benefits from Pycnogenol?

While acute antioxidant protection begins within hours of ingestion, clinical research shows microcirculatory and endothelial blood flow enhancements generally develop within 2 to 4 weeks of consistent daily usage. Joint comfort, skin hydration, and connective tissue benefits typically reach peak expression between 6 and 12 weeks.

Can I take Pycnogenol with other antioxidants like Vitamin C, E, or CoQ10?

Yes. Pycnogenol® acts synergistically with other network antioxidants. Research indicates that French maritime pine bark proanthocyanidins help regenerate oxidized vitamin C and protect vitamin E, amplifying overall cellular defense. It pairs effectively with CoQ10 for cardiovascular support.

Is Pycnogenol the same as Grape Seed Extract?

No. Although both extracts contain oligomeric proanthocyanidins (OPCs), Pycnogenol® is derived specifically from the coastal maritime pine (Pinus pinaster) and possesses a unique ratio of monomeric polyphenols and organic caffeic, ferulic, and taxifolin acids that have been validated through exclusive clinical trials.

Should Pycnogenol 100 mg be taken in the morning or evening?

Pycnogenol can be taken at any time of day, but most practitioners suggest taking it in the morning or early afternoon with a meal. Because it supports healthy blood flow and cellular oxygen delivery, some individuals experience a mild natural sense of vitality and prefer not taking it immediately before bed.
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