Vegetarian Systemic Enzyme for Cardiovascular Cleansing & Healthy Tissue Repair
Source Naturals Serrapeptase is a premium vegetarian systemic enzyme designed to support your body's natural healing cycle. Formulated to provide a minimum of 60,000 Serrapeptase Units (SPU) per 2-capsule serving, this potent formula acts as a metabolic cleaner. It naturally eases minor pain and inflammation from over-exertion or everyday activities by dissolving extraneous fibrin, thick mucus, and cellular debris that gather when your tissues work to repair themselves.
✓Cardiovascular & Arterial Health: Promotes clear blood flow by breaking down unwanted non-living protein build-up.
✓Joint & Muscle Comfort: Moderates inflammatory compounds to ease recovery after physical exercise.
✓Fluid Drainage & Sinus Relief: Thins dense mucus secretions in nasal pathways and bronchial tracts.
✓Targeted Delivery: Features a specialized gastro-resistant coating so the enzyme survives harsh stomach acid and absorbs intact.
How Serrapeptase Works: The Body's Internal Cleanup Crew
Most digestive enzymes focus on breaking down proteins, fats, and carbohydrates inside your stomach. Serrapeptase (also known as serratiopeptidase) belongs to a distinct category called systemic proteolytic enzymes. Instead of assisting with meal digestion, it passes through the intestinal barrier into the bloodstream to work throughout the entire vascular and muscular system.
Think of serrapeptase as a targeted biological filter. It possesses the rare ability to distinguish between living, healthy cells and dead or damaged tissue. When tissues suffer stress from hard exercise, repetitive movement, or normal aging, your body generates excess fibrin—a dense, mesh-like protein that acts like internal biological glue. While temporary fibrin nets are essential to seal cuts, residual fibrin buildup can restrict micro-circulation, prolong swelling, and keep nerves irritated.
Serrapeptase systematically hydrolyzes (breaks apart) this surplus fibrin without touching living cellular linings. In parallel, it breaks down excess kinins (chemical messengers that signal throbbing sensations to the nervous system), allowing blood to circulate smoothly and promoting natural drainage around congested joints and air passages.
Primary Health Benefits Explained in Plain English
1. Promotes Cardiovascular and Arterial Health
Over time, dead cells, cellular debris, and fibrous tissue can build up along vascular pathways. By selectively breaking down extraneous protein strands in the bloodstream, serrapeptase helps sustain smooth arterial linings, prevents fluid congestion, and assists normal microvascular tone.
2. Eases Everyday Soreness and Speeds Recovery
Whether caused by heavy yard work, weight training, or extended desk posture, overexertion leads to minor inflammatory pooling. Serrapeptase clears post-exertion debris and relieves pressure on sensitive nerve endings, helping joints, tendons, and muscles bounce back more quickly without irritating the stomach lining.
3. Supports Sinus, Lung, and Respiratory Drainage
Mucus is largely composed of dense glycoproteins. Serrapeptase alters the viscosity (thickness and stickiness) of mucus secretions in the sinus cavities and lungs. By turning thick, trapped secretions into thinner, fluid discharge, it allows your cilia (tiny microscopic hairs in your respiratory tract) to clear pathways naturally.
Clinical Evidence & Scientific Citations
Originally isolated from the non-pathogenic intestinal bacterium Serratia strain E-15 found in the digestive tract of the silkworm, serrapeptase has been investigated across Europe and Asia for more than 40 years.
Respiratory Secretions & Clearance: A double-blind clinical study demonstrated that oral serratiopeptidase significantly reduced the viscosity and elasticity of nasal and bronchial mucus, enhancing mucociliary clearance in patients with chronic airway congestion (Majima et al., Japanese Journal of Medical Science & Biology, 1990).
Inflammatory Response & Edema: Multicenter randomized trials demonstrated that oral serrapeptase administered after ear, nose, and throat discomfort led to rapid improvements in swelling, localized congestion, and tissue discomfort compared to placebo (Mazzone et al., Journal of International Medical Research, 1990).
Tissue Repair & Swelling Reduction: Clinical evaluations confirmed that serrapeptase aids natural fluid reabsorption and supports microvascular recovery without causing gastric ulcers commonly associated with non-steroidal anti-inflammatory agents (Bhagat et al., International Journal of Surgery, 2013).
Scientific Reference List:
1. Majima, Y., et al. (1990). "The effect of an orally administered proteolytic enzyme (serrapeptase) on the rheological properties of mucus." Jpn J Med Sci Biol, 43(3): 89–97.
2. Mazzone, A., et al. (1990). "Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind, randomized trial versus placebo." J Int Med Res, 18(5): 379–388.
3. Bhagat, S., et al. (2013). "Serratiopeptidase: a systematic review of the existing evidence." Int J Surg, 11(3): 209–217.
Serrapeptase (providing a minimum of 60,000 Serrapeptase Units [SPU])
1 g (1,000 mg)
†
† Daily Value not established.
Other Ingredients: Rice flour, hydroxypropyl methylcellulose and water (vegetarian capsule), hydroxypropyl methylcellulose phthalate, and polyethylene glycol.
Why the Coating Matters: Serrapeptase is a sensitive, acid-labile protein. Hydroxypropyl methylcellulose phthalate provides an enteric shield that protects the enzyme from denaturing in strong hydrochloric stomach acid (pH 1.5–2.5). The capsule dissolves only after reaching the neutral pH of your small intestine (pH 6.5–7.5), ensuring complete bioavailability.
Dietary Suitability: Contains no yeast, dairy, egg, gluten, soy, or wheat. Suitable for vegetarians. Contains no sugar, preservatives, or artificial colors, flavors, or fragrances.
Crucial Empty Stomach Rule: Systemic enzymes must always be taken on an empty stomach. Take your dose at least 45 to 60 minutes before meals, or wait at least 2 hours after eating. Swallow with at least 8 ounces of water. If taken with food, the enzyme will exhaust its catalytic power digesting meal proteins instead of entering your blood supply.
Important Safety Information & Contraindications
Blood-Thinning Medication: Do not use without consulting your physician if you take prescription blood thinners or anti-platelet medications (such as warfarin/Coumadin, heparin, Plavix, or daily aspirin) or high-dose vitamin K, as serrapeptase can enhance fibrin clearance and alter blood coagulation parameters.
Surgeries & Dental Procedures: Discontinue use at least two weeks before any scheduled surgery or dental extraction to avoid prolonged bleeding time.
Gastrointestinal Disorders: Do not take if you have active stomach ulcers, erosive gastritis, or severe gastrointestinal inflammation.
Pregnancy & Nursing: Do not take if you are pregnant, may become pregnant, or are currently breastfeeding.
Adverse Reactions: Discontinue use immediately if you develop nausea, upset stomach, diarrhea, or a cutaneous skin rash. Keep out of reach of children.
Frequently Asked Questions (FAQ)
What does "60,000 SPU" mean?
SPU stands for Serrapeptase Units. Unlike minerals measured purely by weight (like milligrams), enzymes are measured by their active biological strength—specifically how fast they break down protein in laboratory tests. A 2-capsule serving provides 1,000 mg of material delivering at least 60,000 active units of enzyme potency.
How long does it take for serrapeptase to work?
Individual timelines vary based on your personal health goals. For minor joint stiffness, exercise recovery, and sinus congestion, many individuals note positive differences within 3 to 7 days of daily use on an empty stomach. For long-term cardiovascular and arterial support, systemic enzymes are commonly taken consistently for 4 to 12 weeks.
Why do I have to take serrapeptase on an empty stomach?
Serrapeptase is a systemic enzyme, not a digestive aid. If food is present in your stomach, the enzyme will bind to dietary protein and digest your meal rather than passing into your blood vessels to clear systemic fibrin, mucus, and cellular waste.
Is this product completely vegetarian?
Yes. Although serrapeptase was historically discovered in the gut of silkworms, Source Naturals produces its enzyme using vegetarian fermentation from non-pathogenic Serratia cultures. It is enclosed in a vegetarian cellulose capsule and contains no animal byproducts.
Can I take serrapeptase alongside daily pain relievers or blood pressure medicine?
You should always consult your primary healthcare practitioner before combining serrapeptase with prescription drugs. Because serrapeptase naturally dissolves excess fibrin, pairing it with pharmaceutical blood thinners (such as warfarin or aspirin) may compound anti-clotting effects.
FDA / Medical Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or dietary supplementation.
