Source Naturals Magnesium Glycinate: High-Absorption Chelated Mineral for Deep Sleep, Calm, and Muscle Health
Source Naturals Magnesium Glycinate (Item #SN2890) delivers an optimized 200 mg of elemental magnesium per 2-tablet serving in its most bioavailable, gut-friendly chelated form. Bonded directly to the soothing amino acid glycine, this advanced bisglycinate complex bypasses common digestive roadblocks to deliver restorative calm, relaxed muscles, and cardiovascular balance directly to your cells without the unwanted laxative effect.
VitaNet® Quality Guarantee: Serving conscious health seekers online since 1995. Every bottle of Source Naturals Magnesium Glycinate is sourced straight from certified Good Manufacturing Practice (cGMP) facilities, lab-tested for heavy metals and potency, and supported by our unmatched 100% money-back guarantee.
✓ Superior Chelation
100% bound to glycine for smooth absorption through peptide pathways.
✓ Gentle on Digestion
Eliminates the rapid bowel flushing commonly triggered by cheap oxide forms.
✓ Dual Action Calm
Synergistic magnesium and glycine soothe tired nerves and prime your brain for deep REM rest.
✓ Pure & Hypoallergenic
Free from gluten, dairy, soy, wheat, corn, sugar, and synthetic additives.
What Sets Magnesium Glycinate Apart? The Science of Chelation Explained in Plain English
Magnesium is an indispensable macro-mineral involved in over 300 essential enzymatic reactions across the human body, ranging from cellular energy (ATP) production to DNA repair and healthy heartbeat regulation. Yet national dietary surveys indicate that more than 50% to 75% of American adults fail to meet the Recommended Dietary Allowance (RDA) through food alone (Gröber et al., 2015).
However, simply grabbing any bottle of magnesium off the shelf is rarely the answer. In raw mineral supplements, elemental magnesium carries an electrical charge. When it hits stomach acid, it frequently breaks apart prematurely, attracting water into your large intestine through osmosis. The outcome? Uncomfortable cramping, loose stools, and very little actual mineral reaching your cells.
The "Trojan Horse" Chelation Advantage
Source Naturals Magnesium Glycinate solves this dilemma through true molecular chelation. In this formula, each magnesium ion is bonded between two molecules of glycine (the smallest natural amino acid). Think of these glycine molecules as a protective organic coat. Because your gastrointestinal tract recognizes glycine as a nutrient, it transports the intact compound through specialized dipeptide pathways in the jejunum instead of relying on congested ionic mineral channels. As proven in clinical research published in the Journal of Parenteral and Enteral Nutrition, chelated bisglycinate is absorbed intact, significantly outperforming non-chelated options even in people with compromised digestion (Schuette et al., 1994).
Comparing Forms: Why Glycinate Outranks Oxide and Citrate
Evidence-Based Benefits: How Source Naturals Magnesium Glycinate Works in Your Body
When you take Source Naturals Magnesium Glycinate, you are not just fueling up on elemental magnesium; you are receiving the compounding benefits of magnesium coupled with bio-active glycine. Peer-reviewed clinical trials highlight four primary areas of full-body support:
Do you wake up feeling like you barely slept, or struggle to turn off a racing mind at night? Magnesium binds to and stimulates gamma-aminobutyric acid (GABA) receptors in the brain. GABA is your body's primary inhibitory neurotransmitter—it acts as the neurological "brake pedal," calming nervous excitability and helping you drift into sleep smoothly.
In a double-blind, randomized controlled trial conducted by Abbasi et al. (2012), individuals supplementing with magnesium experienced statistically significant improvements in sleep efficiency, total sleep duration, sleep onset latency (falling asleep faster), and early morning awakenings, alongside increased serum melatonin levels and decreased cortisol. Simultaneously, clinical studies by Bannai and Kawai (2012) demonstrated that oral glycine specifically promotes rapid sleep onset by naturally decreasing nocturnal core body temperature and stabilizing slow-wave deep sleep cycles without the grogginess associated with sleeping pills.
2. Nervous System Calm & Stress Management
Chronic physical and psychological stress depletes your body's magnesium reserves rapidly through urinary excretion. Low magnesium levels make the nervous system hyper-reactive, perpetuating a vicious cycle of tension. In a comprehensive systematic review, Boyle, Lawton, and Dye (2017) demonstrated that daily magnesium supplementation provides measurable therapeutic relief for subjective anxiety, irritability, and stress responsiveness by modulating the hypothalamic-pituitary-adrenal (HPA) axis and blunting excess cortisol output.
3. Muscle Relaxation & Relief from Nighttime Cramping
Calcium initiates muscle contraction, while magnesium directs muscles to relax. When this mineral ratio falls out of balance, muscle fibers remain locked in persistent tension, causing daytime neck stiffness, twitching eyelids, and painful nighttime leg cramps (charley horses). Daily supplementation replenishes intra-cellular stores, enabling smooth neuromuscular signaling, rapid exercise recovery, and uninterrupted nocturnal rest.
4. Cardiovascular Tone & Skeletal Bone Density
Approximately 60% of your body's magnesium is stored in bone tissue, where it works with vitamin D and osteocalcin to draw calcium out of bloodstream walls and bind it into bone matrix (Castiglioni et al., 2013). Simultaneously, magnesium keeps vascular smooth muscle pliable, encouraging balanced blood pressure and healthy cardiac rhythm stability.
At VitaNet®, we believe you should know precisely what is in every tablet you take. Below is the verified label information for Source Naturals Magnesium Glycinate - 60 Tablets (UPC: 021078028901, SKU: SN2890).
Supplement Facts
Serving Size: 2 Tablets
Servings Per Container: 30
Amount Per Serving
% Daily Value
Dietary Fiber 1 g
4%*
Calcium (as dibasic calcium phosphate) 95 mg
7%
Magnesium (as magnesium bis-glycinate) 200 mg
48%
Sodium 10 mg
<1%
* Percent Daily Values (%DV) are based on a 2,000 calorie diet.
Contains NO: Yeast, dairy, egg, gluten, corn, soy, or wheat. Formulated with zero sugar, starch, artificial preservatives, synthetic colors, artificial flavors, or fragrances. Suitable for vegetarians.
Practical Usage Guide: When, How, and What Dosage to Take
Getting optimal results from your magnesium regimen comes down to timing and consistency. Because your body uses magnesium around the clock, steady daily intake produces the most noticeable benefits.
Suggested Manufacturer Dosage
Take 2 tablets twice daily with a glass of water, or as advised by your healthcare professional. This provides 400 mg of elemental magnesium daily, replenishing stores safely within standard daily allowances.
Best Timing for Sleep Support
If your primary goal is tranquil sleep and muscle recovery, take 2 tablets 30 to 60 minutes before bed. For daytime tension or stress, take 1 or 2 tablets with breakfast or lunch.
What Results Should You Expect and When?
Night 1 to Week 1: Physical tension eases before bed. Many users report falling asleep faster and experiencing fewer involuntary leg twitches or nocturnal spasms.
Weeks 2 to 4: Deeper, uninterrupted sleep cycles. Morning grogginess decreases, and daytime resilience to workplace stress and irritability increases.
Month 2 and Beyond: Restored intracellular magnesium levels support cellular energy production, steady cardiovascular tone, and enhanced mineral density in bone tissue.
Safety, Tolerability, and Drug Interaction Guardrails
As part of our commitment to responsible healthcare, supplement education requires absolute transparency regarding contraindications and medication interactions.
Important Precautions & Medical Considerations
Kidney Function: The kidneys are solely responsible for excreting excess magnesium. Individuals with severe renal impairment, chronic kidney disease (CKD), or kidney failure should not take magnesium supplements without direct nephrologist clearance.
Heart Block: Those diagnosed with high-grade atrioventricular (AV) heart block should avoid supplemental magnesium unless supervised by a cardiologist.
Pregnancy & Nursing: If you are pregnant, planning to become pregnant, or breastfeeding, consult your OB/GYN or midwife before introducing new mineral supplements.
Prescription Medication Timing (Avoid Mineral Binding)
Magnesium can bind with several prescription pharmaceuticals in the digestive tract, lowering how much medicine your body absorbs. Follow these standard spacing guidelines:
Antibiotics (Tetracyclines & Fluoroquinolones): Take at least 2 hours before or 4 to 6 hours after magnesium.
Thyroid Medication (Levothyroxine): Separate by at least 4 hours to avoid reduced thyroid hormone absorption.
Bisphosphonates (Osteoporosis drugs): Take magnesium at least 2 hours after your osteoporosis medication.
Blood Pressure / Diuretic Drugs: Potassium-sparing diuretics can increase magnesium levels, while loop diuretics deplete them. Discuss routine electrolyte panels with your doctor.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
California Proposition 65 Notice: California law requires special notification for dietary supplements regarding naturally occurring trace minerals in soil. Source Naturals complies strictly with all FDA Good Manufacturing Practice regulations and testing requirements for botanical and mineral safety.
Our educational content is held to rigorous scientific standards. Below are the verified medical citations referenced throughout this guide:
Schuette, S. A., Lashner, B. A., & Janghorbani, M. (1994). Bioavailability of magnesium diglycinate vs magnesium oxide in patients with ileal resection. JPEN: Journal of Parenteral and Enteral Nutrition, 18(5), 430–435. PMID: 7815675. [Demonstrates amino acid chelated magnesium is absorbed intact via dipeptide channels without osmotic irritation].
Abbasi, B., Kimiagar, M., Sadeghniiat, K., Shirazi, M. M., Hedayati, M., & Rashidkhani, B. (2012). The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. Journal of Research in Medical Sciences, 17(12), 1161–1169. PMID: 23853635. [Confirms substantial improvements in sleep efficiency, sleep onset latency, sleep duration, and melatonin balance].
Boyle, N. B., Lawton, C., & Dye, L. (2017). The Effects of Magnesium Supplementation on Subjective Anxiety and Stress—A Systematic Review. Nutrients, 9(5), 429. doi:10.3390/nu9050429. [Validates the role of magnesium in modulating the neurological stress response and dampening central nervous system excitability].
Bannai, M., & Kawai, N. (2012). New therapeutic strategy for amino acid medicine: glycine improves sleep quality. Journal of Pharmacological Sciences, 118(2), 145–148. PMID: 22293292. [Documents glycine's hypothermic and NMDA-mediated sleep-induction pathways].
Gröber, U., Schmidt, J., & Kisters, K. (2015). Magnesium in Prevention and Therapy. Nutrients, 7(9), 8199–8226. doi:10.3390/nu7098199. [Examines population-level magnesium deficiencies and physiological co-factor mechanisms in 300+ cellular enzymes].
Castiglioni, S., Cazzaniga, A., Albisetti, W., & Maier, J. A. (2013). Magnesium and Osteoporosis: Current State of Knowledge and Future Research Directions. Nutrients, 5(8), 3022–3033. doi:10.3390/nu5083022. [Highlights the synergistic role of magnesium in bone crystal structure and calcium regulation].
Frequently Asked Questions (FAQ) About Source Naturals Magnesium Glycinate
Q: What is the difference between magnesium glycinate and magnesium bisglycinate?
A: They are two names for the exact same nutrient form. "Bisglycinate" is the scientific chemical name, where the prefix "bis" indicates that one magnesium atom is bound between two glycine amino acid molecules. On many consumer labels, including Source Naturals, the compound is labeled as magnesium glycinate for simplicity. Rest assured you are receiving true, high-potency bisglycinate chelate.
Q: How much elemental magnesium do I get per serving?
A: Each 2-tablet serving provides 200 mg of elemental magnesium (48% of your Daily Value). The total weight of the tablet is heavier because it includes the glycine amino acid carriers. If you follow the suggested use of 2 tablets twice daily, you receive 400 mg of usable elemental magnesium daily.
Q: Will this magnesium cause loose bowels or diarrhea?
A: It is exceptionally unlikely. Cheap forms like magnesium oxide draw unabsorbed water into your colon, triggering a sudden laxative rush. Because magnesium glycinate is tightly bound to amino acids, it gets absorbed high in your intestinal tract through peptide carriers, making it exceptionally gentle on sensitive stomachs.
Q: Can I take all 4 tablets at bedtime?
A: While many customers take 2 tablets 45 minutes before sleep for tranquil rest, taking all 4 tablets at once is generally not necessary unless recommended by your doctor. Dividing your intake (for example, 2 tablets with dinner and 2 tablets before bed) allows your cellular mineral transporters to absorb the nutrient with peak efficiency.
Q: Why is calcium listed on the supplement facts label?
A: Source Naturals uses dibasic calcium phosphate as a clean, inert tableting binder. This naturally provides 95 mg of calcium per serving (7% of your Daily Value). Calcium and magnesium naturally balance one another in your neuromuscular signaling pathways.
Q: How long does one 60-tablet bottle last?
A: At the standard serving size of 2 tablets daily (200 mg elemental magnesium), one bottle represents a 30-day supply. If taken at the intensive manufacturer dosage of 2 tablets twice daily (400 mg elemental magnesium), one bottle will last 15 days.
