Expert Clinical Overview: Magnesium is an essential cofactor in more than 300 metabolic reactions. Pairing pure magnesium with the calming amino acid glycine creates an organic chelate designed for rapid uptake without the digestive upset common in standard oxide forms.
If you experience tight muscles after a long day, restless nights, or daily physical tension, your body may be asking for more usable magnesium. While standard drugstore forms like magnesium oxide often pass right through you and cause a laxative effect, Source Naturals Magnesium Glycinate couples elemental magnesium to two glycine molecules. This gentle chelated mineral enters your system effortlessly through dipeptide absorption pathways, delivering cellular relaxation where you need it most.
✓Gentle on Sensitive Stomachs: Fully chelated bis-glycinate reduces the loose stools and cramping common with non-chelated mineral salts.
✓Deep Sleep & Evening Calm: Glycine crosses the blood-brain barrier to promote GABA synthesis, quieting racing thoughts before bed.
✓Rapid Muscle Recovery: Balances intracellular calcium to relieve leg cramps, tension, and twitching from workouts or daily stress.
✓Clean & Tested Formula: 100% vegetarian, non-GMO, and free from gluten, yeast, dairy, soy, egg, corn, and artificial preservatives.
Why Chelated Magnesium Glycinate Works Better
Not all magnesium supplements work the same way inside your digestive tract. Basic magnesium salts (like oxide or sulfate) require strong stomach acid to separate the mineral ion. Once separated, unabsorbed ions pull water into your bowel, frequently leading to diarrhea before the mineral can ever be utilized.
The Chelation Advantage: In Source Naturals Magnesium Glycinate (often chemically called magnesium bis-glycinate), elemental magnesium is chemically bonded to two molecules of the non-essential amino acid glycine. Your intestines recognize this complex as a peptide rather than an unbonded mineral salt. It is absorbed whole through amino acid channels (dipeptide transporters), bypassing standard mineral competition in your gut.
Quick Comparison: Glycinate vs. Common Magnesium Forms
Form
Absorption Level
Stomach Comfort
Best Used For
Magnesium Glycinate
Superior (High Bioavailability)
Very Gentle (Non-laxative)
Sleep, Anxiety, Cramps, Restoration
Magnesium Oxide
Poor (approx. 4%)
Common Cause of Loose Stool
Short-term Constipation Relief
Magnesium Citrate
Moderate to High
Mild Osmotic Laxative Effect
Bowel Regularity with Mineral Support
Evidence-Based Health Benefits & Scientific Citations
According to national nutritional surveillance data from the National Institutes of Health (NIH), nearly half of all Americans consume less than the Estimated Average Requirement (EAR) of dietary magnesium. Source Naturals provides a concentrated way to bridge this gap:
1. Restful Sleep & Neuromuscular Calm
Magnesium acts as a natural gatekeeper for N-methyl-D-aspartate (NMDA) receptors in the brain, preventing neurons from becoming overstimulated. Paired with glycine, which acts as an inhibitory neurotransmitter in the brain stem and spinal cord, it helps lower your internal body temperature and prepares the central nervous system for deep restorative sleep (Kawai et al., 2015; Abbasi et al., 2012).
2. Muscle Cramps, Spasms & Recovery
While calcium causes muscle fibers to contract, magnesium stimulates the reuptake of calcium back into the sarcoplasmic reticulum, signaling muscle fibers to release and unwind. Daily supplementation helps decrease nighttime calf twitches, spasms, and tension after demanding workouts.
3. Cardiovascular Rhythm & Blood Pressure Support
Magnesium regulates vascular smooth muscle tone and maintains proper cardiac conduction. Clinical analyses show that balanced magnesium intake supports healthy systolic and diastolic blood pressure levels already within normal range (Zhang et al., 2016).
Scientific Citations:
Abbasi, B., et al. (2012). The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci, 17(12), 1161–1169. [PMID: 23853635]
Kawai, N., et al. (2015). The sleep-promoting and hypothermic effects of glycine are mediated by NMDA receptors in the suprachiasmatic nucleus. Neuropsychopharmacology, 40(6), 1405–1416. [PMID: 25533534]
Zhang, X., et al. (2016). Effects of Magnesium Supplementation on Blood Pressure: A Meta-Analysis of Randomized Double-Blind Placebo-Controlled Trials. Hypertension, 68(2), 324–333. [PMID: 27402922]
National Institutes of Health Office of Dietary Supplements (ODS). Magnesium Fact Sheet for Health Professionals. ods.od.nih.gov.
Complete Supplement Facts & Ingredient Listing
Every tablet is produced under strict current Good Manufacturing Practices (cGMP) guidelines set by the FDA and verified by in-house laboratory testing.
* Percent Daily Values (%DV) are based on a 2,000 calorie diet.
Other Ingredients: Microcrystalline cellulose, dibasic calcium phosphate, stearic acid, modified cellulose gum, hydroxypropyl cellulose, magnesium stearate, and silica.
Allergen Free Guarantee: Contains NO yeast, dairy, egg, gluten, corn, soy, or wheat. Contains NO sugar, starch, artificial colors, artificial flavors, or synthetic fragrances. Suitable for vegetarians.
How to Take: Suggested Usage & Best Timing
Suggested Use: Take 2 tablets twice daily with meals, or take 2 tablets 30–60 minutes before bedtime to encourage nighttime relaxation and uninterrupted sleep.
For Muscle Relaxation: Take 2 tablets after physical activity with a tall glass of water.
For Stress & Sleep: Take 2 tablets in the evening alongside a light snack.
Consistency Matters: Magnesium works best when taken consistently over 4 to 8 weeks to replenish cellular tissue stores.
Precautionary Guidance: If you are pregnant, nursing, have severe kidney disease, or are currently taking heart medications or antibiotics (such as tetracyclines or fluoroquinolones), consult your healthcare practitioner prior to taking this supplement. Separate magnesium intake from antibiotics by at least 2 to 3 hours.
The VitaNet® Quality Commitment – Serving You Since 1995
At VitaNet®, we believe supplement shopping should be completely trustworthy. That is why we provide three distinct safeguards with every bottle of Source Naturals Magnesium Glycinate:
✓ 100% Money-Back Guarantee (12 Full Months)
We stand behind every bottle. If you are unsatisfied for any reason within one full year of purchase, we will refund 100% of your product purchase price and pay the return shipping—whether opened or unopened.
✓ Fresh Batches Guaranteed
We receive frequent shipments directly from Source Naturals warehouses. Your product is stored in climate-controlled environments so potency remains high from the first tablet to the last.
✓ Direct Customer Care & A+ BBB Accreditation
Have a question about your order? You can reach our dedicated vitamin wellness team directly at 1-800-877-8702 or visit our storefront in Hartville, Ohio.
Frequently Asked Questions (FAQ)
What is magnesium glycinate best used for?
Magnesium glycinate is best used for promoting restful sleep, calming everyday nervous tension, easing muscle cramps, and restoring healthy mineral levels without the loose stools or stomach upset caused by standard magnesium supplements.
Does Source Naturals Magnesium Glycinate cause diarrhea or upset stomach?
No, it is significantly gentler than other forms. Because the elemental magnesium is chelated to glycine, your body absorbs it through amino acid transport channels rather than pulling large amounts of water into the intestine, virtually eliminating laxative side effects when taken at directed amounts.
What is the best time of day to take magnesium glycinate?
You can take it any time with food. However, if your primary goal is relaxation or sleep support, most users take their serving 30 to 60 minutes before going to bed. For general daily wellness or athletic recovery, taking 2 tablets in the morning and 2 tablets in the evening is recommended.
How much elemental magnesium is in each serving of Source Naturals?
A full 2-tablet serving supplies 200 mg of elemental magnesium (as magnesium bis-glycinate chelate), providing 48% of the adult Daily Value. One bottle contains 180 tablets, which equals a 45 to 90-day supply depending on your daily regimen.
Is this product free from common allergens?
Yes. Source Naturals Magnesium Glycinate contains no yeast, dairy, egg, gluten, corn, soy, or wheat. It is also formulated without sugar, starch, preservatives, artificial colors, artificial flavors, or fragrances, and is completely suitable for vegetarians.