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Mushroom Immune Defense - Scientific Immunity Formula Darrell Miller 6/4/05
MaitakeGold 404® and Certified immune-stimulative activity ... Darrell Miller 5/26/05




Mushroom Immune Defense - Scientific Immunity Formula
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Date: June 04, 2005 10:08 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Mushroom Immune Defense - Scientific Immunity Formula

Mushroom

The immune system is a fascinating and complex group of cells and biochemical processes. Its many components work to protect you from environmental threats—but your immune system requires nutritional support to function optimally. Scientific research is proving that some of the most powerful immune-supportive nutrients are found in mushrooms. People who realize the critical importance of optimizing immune function should seriously consider adding an advanced mushroom complex to their daily regimen. No other mushroom formula offers the high-potency, broad-spectrum benefits of Source Naturals MUSHROOM IMMUNE DEFENSE. MUSHROOM IMMUNE DEFENSE features 16 of the best-studied species of health-supportive mushrooms, including shiitake, reishi, and maitake. These mushrooms contain compounds, including beta-glucans, glycoproteins and polysaccharides, that support a wide range of immune defenses: natural killer cell, T-cell and macrophage activity, and cytokine production. By combining a wide variety of mushrooms and fortifying them with extracts to ensure high potency, MUSHROOM IMMUNE DEFENSE offers a biochemically diverse formula that provides optimum immune assistance.

How Do Mushrooms Work?

Mushrooms are a treasure trove of bioactive compounds, but most of their immunomodulating activities have been attributed to polysaccharides (long-chain, simple sugars) and glycoproteins (polysaccharides naturally associated with proteins). These compounds activate a variety of immune responses.

Broad-Range Protection

MUSHROOM IMMUNE DEFENSE contains mycelia (networks of fibrous filaments) and extracts from the widest variety of mushroom species available. Included are the following mushrooms, which have demonstrated the most evidence for immune defense. Shiitake (Lentinula edodes): Lentinan, the beta glucan from shiitake, has been studied more extensively than similar substances and may be one of the most effective immunomodulators. Numerous studies have shown its ability to stimulate natural killer cell, T-cell, and macrophage-dependent responses.

Reishi (Ganoderma lucidum): Reishi’s polysaccharides may stimulate macrophages and enhance T-cell proliferation, according to in vitro studies.

Maitake (Grifola frondosa): Maitake enhances the activities of natural killer cells, T-cells and macrophages, according to animal studies. MUSHROOM IMMUNE DEFENSE contains MaitakeGold 404™, a highly specialized maitake product, rich in beta-glucans, which is the only maitake betaglucan fraction endorsed by the world’s premier maitake researcher, Dr. Hiroaki Nanba, Ph.D. Turkey Tails (Trametes versicolor): These mushrooms have a long history of traditional use in Asia. One in vitro study suggests that its polysaccharides stimulate macrophages.

Almond portabella (Agaricus blazei): This mushroom may stimulate the immune system by increasing T-cell activity, according to animal studies.

Cordyceps (Cordyceps sinensis): Cordyceps came to international attention during National Games in China when, in one week, three women’s track and field world records were broken. The coach partially credited a cordyceps elixir. Cordyceps was found to augment antibody and other immune responses in one animal study, and a cordyceps polysaccharide was found to elevate cytokines in vitro.

MUSHROOM IMMUNE DEFENSE contains 10 additional mushrooms, including enoke, oyster, Polyporus umbellatus, and Poria cocos. Vitamin C is added to enhance absorption and activity.

Unparalleled Immune Support

A focus on immune support can pay tremendous dividends for your entire life. If you are dedicated to good health, you want a powerful formula on your side. Source Naturals is proud to join forces with your natural foods retailer to bring you an unparalleled immune formula: MUSHROOM IMMUNE DEFENSE.

References
Kurashige S, et al. 1997. Immunopharmacol Immunotoxicol 1997 19(2):175-83. Wang S. Y. et al. 1994. Program and Abstracts of the ’94 International Symposium on Ganoderma Research. Beijing: Beijing Medical University. Wasser S. P. and Weis A. L. 1999a. Crit Rev Immunol, 19, 65-96.



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MaitakeGold 404® and Certified immune-stimulative activity ...
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Date: May 26, 2005 10:49 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: MaitakeGold 404® and Certified immune-stimulative activity ...

Dr. Nanba's Maitake Beta Factor & Dr. Nanba's Maitake-Pro Certified Immune-Stimulative Activity

By now, many people are aware of the numerous benefits of mushrooms, especially for immune health. But not all mushroom products are created equal. Planetary formulas offers Dr. Nanba's Maitake Beta Factor and Dr. Nanba's Maitake Pro. These products feature MaitakeGold 404®, a specialized beta glucan fraction with important health promoting properties. And every lot comes with certified proof of immune bioactivity -- so customers can be assured they are getting the benefits they look for in a mushroom product.

Immune Active Certification program

The Tradeworks Group, Inc., supplier of MaitakeGold 400® and planetary formulas' exclusive supplier for dr. nanba's maitake beta factor an d Maitake pro, has introduced a new and unprecedented quality assurance program. The Immunactive Certification program provides MaitakeGold 404® licensees with proof of in vivo immune activity analysis for every lot of MaitakeGold 404®. Each lot is independently tested at the University of Louisville school of Medicine to validate its phagocytosis activity.

Phagocytosis is the process by which cells (White blood cells, for example) engulf and digest foreign organisms. As the body's first line of immune defense, phagocytosis is understoood to be one of the most important activities in immunology. For an immune support prodcut to be of benefit, it must be able to stimulate phagocytosis, thereby protecting the body against daily health chellenges.

Based on this testing, Maitake Gold 404® has been shown to be a consistent and potent immunostimulant.

Certification Exceeds Conventional Industry Standards

The biological assays provided under the ImmuneActive certification program offer customers a form of quality control that goes beyond the chemical analyses typically provided by companies, according to Roy Upton, herbalist and Planetary Formulas General Manager. "Most all comnpanies perform some type of quality control test," Upton said. "However, a biological assay measuring activity is often much better than chemical charaterization. Because of the important role maitake plays in support of healthy immune system, it is important that activity, not just chemistry be delivered. People depend on its immune system activity, not its chemistry."

Endorsed by world's Premier Maitake Researcher

MaitakeGold 404® is the only maitake extract endorsed by award-winning mushroom researcher, Dr. Hiroaki Nanba, PH.d. It was Dr. Nanba's research that led to the discovery of the beta glucan fraction known as MaitakeGold 404®.

MAitakeGold 404® is a trademark of the Tradeworks Group, Inc., and is protected under U.S. Patent # 5,854,404



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