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Olive oil could slash your chance of bone fractures in half, study says
February 01, 2017 12:59 PM
Extra virgin olive oil could have better benefits besides making your meals taste better. A recent study found that people who regularly consume EVOO have a decreased risk of osteoporosis and bone fracture. When regular olive oil was analyzed, it was not found to have the same benefits. The reason behind this difference is believed to be due to the greater amount of processing. The olives that are pressed into EVOO contains the highest amounts of antioxidants and bio-active compounds.
"Eating more extra virgin olive oil could cut your risk of osteoporosis related fractures, says a new study."
Eye Inflammation and one Herb To Prevent It!
What is eye inflammation?
The one single most important herb anybody can take to reduce inflammation, in the eye as well as systemic inflammation is "curcumin." Curcumin is the most powerful substance discovered so far in nature which naturally lowers inflammation with zero side effects. If you have followed the above list of ways to help reduce inflammation and you still struggle with eye inflammation, consider taking curcumin daily to eliminate inflammation throughout the body!
For more information visit: //www.webmd.com/first-aid/eyelid-inflammation-blepharitis-treatment
Acne Treatment of Different Skin Types
September 20, 2011 11:30 AM
Not everyone has the same skin type, and if you have acne, then the treatment could be dependent on your skin type. Before discussing the different acne treatments available, therefore, it will be necessary to discuss the various skin types.
Skin types are graded in a number of ways, anything from 3 types to several. Here we shall discuss more than the normal three (oily, dry and normal) but instead look at seven.
1. Normal Skin
Normal skin looks evenly colored and textured, firm and smooth without larger pores. People with normal skin probably had mild acne when at high school, but cleared up fairly quickly during the teenage years without specialized treatment or scarring. Acne in this type of skin normally requires only mild topical treatment and a mild antibiotic face wash to keep the pores clean of dead skin cells.
Treatments designed to reduce sebum production could result in dry skin susceptible to environmental damage. What must be kept in mind is that the prime cause of acne is excessive production of skin oil, correctly known as sebum, becoming mixed with shed skin cells within the sebaceous pores and plugging them. When this plug gets infected with bacteria, the immune system leaps into action to produce puss through leucocytes attacking the bacteria, and inflammation designed to create temperature conditions alien to bacteria.
If you use treatments formulated to reduce sebum production in oily skin, then you might lose the natural skin oil needed to keep your skin waterproof and resistant to the pollution and chemical agents that can cause dermatitis.
2. Dry Skin
If you got through adolescence with few or no skin problems, and you have dry hair and your skin feels dry after washing, then you have dry skin. It is even more important with dry skin that you do not use sebum-reducing treatments, if you even get acne at all. Only the mildest acne treatments should be used if you have dry skin, thought is unlikely that you will get anything other the very mildest case if you really have dry skin.
Your skin can dry through age, so to be of a dry skin type, you should have suffered, or be suffering, these problems while you are 35 years old or under. After that age your skin tends to dry out naturally.
3. Oily Skin
This completes the trilogy of the classic skin types. Oily skin is associated with acne, and if your hair is oily, you tend to tan very easily rather than go red in the sun, and if oily Make-Ups, such as some foundations, tend to last only a short time, then you likely have oily skin.
You will also have suffered from acne as a teenager, and your skin will have a particular 'look'. It will often appear shiny, and will also seem to have a coarse texture with larger pores than most others seem to have. You will tend to get a lot of blackheads, not only as a teenager.
Oily skin is classically associated with acne, and it is for those with that skin type that classic treatments will be prescribed, such as antibiotics and Accutane.
Apart from these three skin types, there are others that have been defined involving a combination of these and also age.
Sensitive skin is associated with broken blood vessels beneath the surface of the skin, and such skin types should be treated very carefully. If creams or lotions are applied to sensitive skin they should be rubbed in very gently as it could cause bruising.
Sensitive skin is no more susceptible to acne than most other skin types although significantly less so than oily skin. For that reason, treatments for sensitive skin should be similar to that for dry skin or in most cases normal skin.
Combination skin has an oily zone across the forehead, and down the nose and chin, the other areas of the face being normal or dry. Such skin can also be oily along the jaw line and normal to dry everywhere else. In such cases aggressive acne treatment might be necessary in the oily zones, and more mild treatments used in the areas which are normal.
There are three other classes or skin type based upon age or condition, one being mature skin and other ailing skin and the final type, surprise, surprise, being known as acne skin. Ailing skin is caused by skin conditions other than acne, and you should get the advice of a dermatologist if you believe you have this type of skin. Mature skin on the other hand is natural and occurs with age: the skin becomes slack and loose due to a slowing down of cell growth which causes the skin to lose elasticity. There is no cure for this type of skin other than cosmetic surgery, and it is rarely affected by acne.
Acne skin is normally oily and associated with blackheads, pimples and spots. It is not normally applied to serious acne conditions, being mostly associated with skin which is generally 'spotty', as opposed to mostly clear. It is debatable whether acne skin is any different from oily skin which also tends to be covered with spots and pimples, and the treatments for acne skin are no different to those for oily skin: these are Accutane, antibiotics and topical treatments such as face washes and scrubs.
If you have acne skin you must be careful about the type of cosmetics and face cleansers you use, since either could aggravate your condition. This is not restricted only to those with oily skins of course, since everyone should be aware of the effect of cosmetics and face cleansers on their skin but it is more significant with those who suffer from acne. Cosmetics cannot cause acne, but they can help to aggravate infections which have already occurred.
Although most focus is placed on those with oily skins which are more susceptible to acne, people with any type of skin should consider carefully the types of cosmetic and cleansers which they use. Contrary to what you may have heard or read, acne has nothing to do with your diet - eating fatty foods or chocolates do not cause acne, which is caused only through production of excess sebum, or skin oil, by the sebaceous glands.
Irrespective of your skin type your physician will determine the best treatment that is appropriate for your particular case of acne. This may be different for individuals and may or may not change according to skin type. Antiseptic face washes or scrubs may be appropriate for some acne cases, Accutane might be the best treatment for others, while a course of internal antibiotics such as tetracyclines may be deemed appropriate for yet other cases.
Treating acne has three distinct phases:
1. Removal of the blackheads and lesions. The removal of lesions can also involve a degree of scar removal, although that is another topic. Black heads, whiteheads and other papules can be treated by the use of facial cleansers and scrubs. They should not be squeezed since the puss inside them could be forced deeper into the skin and so lead to a more generalized infection.
2. Treatment of the bacterial infection. The typical symptoms of acne, the papules, whiteheads and blackheads, are caused by bacterial infection of the plug of sebum and dead skin cells within the sebaceous follicles. The general treatment for such infections is antibiotics, both topically and internally. Tetracycline has already been mentioned as a common internal antibiotic, and several forms of antibiotics are used in facial scrubs of which peroxides and benzoates may perhaps be rather severe for dry and sensitive skins.
3. The third phase is treatment of the causes of excessive sebum production. This is generally not entirely treatable since it is predominantly due to excessive hormonal activity at certain times of your life such as puberty, menstruation, pregnancy and menopause. However, your physician may offer treatments such as the contraceptive pill which should be used with care.
Other treatments include agents that aid desquamation, so preventing the irregular shedding of skin cells that lead to the mixture of sebum and dead skin cells that form the plug that is so easily affected by bacterial infection.
Together these three stages of acne treatment can, if not prevent the condition, certainly reduce its extent and have less of an effect on your skin, particularly if you are the off the oily skin type. Doctors will take your skin type into consideration when determining the best acne treatment for you, although all generally this will only be with respect to topical treatments: treatments that are applied to the surface of your skin.
There are also a number of herbal treatments which are used in the treatment of various stages of acne, and many sufferers find these equally as effective as the more traditional forms of topical applications as prescribed by physicians. However given that the treatment you use is safe according to your physician, any that works for you is the acne treatment that you should likely use, irrespective of your skin type.
L-Alanine Non Essential Amino Acid
January 05, 2009 04:31 PM
L-Alanine is one of 20 amino acids that are used by the body to manufacture the proteins essential for life. Each protein possesses specific biological properties that are imparted by the sequence of amino acids it contains. Proteins control the chemistry that takes place within the cells of our body, and comprise all of the enzymes that catalyze the body's biochemistry.
Amino acids are also the building blocks of DNA that determines the genetic Make-Up of individuals, and that also provides recipes or templates for the production of proteins from amino acid sequences. There is a different DNA template for every protein required by the body that determines which of the 20 amino acids are needed, and in what order they are to be combined with one another to manufacture the desired protein.
10 of these 20 amino acids can be synthesized by your body's biochemistry, the other 10 being essential parts of your diet. If you fail to include just of these 10, then your body will break down its proteins until it has obtained a sufficient supply of that amino acids for its needs. That involves muscle and other tissue degradation, and is one of the symptoms of malnutrition. Amino acids are not stored, and a daily supply is essential to avoid these symptoms.
L-Alanine is one of the ten that the body can manufacture, and used by the body to help build protein and also to enable the body to make use of glucose to generate energy. It does so as part of what is known as the glucose-alanine cycle. During anaerobic exercise, such as in weightlifting and sustained running, muscles produce lactate and also alanine.
The alanine is passed on to the liver where it is converted to energy via its conversion to glucose. This is not a particularly efficient means of creating energy because a byproduct of the process is urea, the removal of which in turn requires energy. However, it serves its purpose as an energy source once the liver is depleted of glycogen. In fact that is the major use to which alanine appears to be put by the body: the conversion of glucose to energy.
The way the glucose-alanine cycle works is that a process known as transamination produces glutamate from the amino groups of amino acids that are degraded during exercise. Glutamate is then converted to pyruvate by means of the enzyme alanine aminotransferase, with the production of alanine and alpha-ketoglutarate. This is a reversible reaction, and after the alanine has been carried by the bloodstream to the liver, the reaction reverses with the regeneration of pyruvate that undergoes gluconeogenesis (generation of glucose).
The result of this is glucose that returns to the muscle tissue to provide more energy. The glutamate is broken down to the ammonium ion in the mitochondria, which in turn enters the urea cycle with the production of urea.
In a nutshell, then, the glucose-alanine cycle removes glutamate and pyruvate from muscle tissue to the liver where glucose is generated from the pyruvate and returned to the muscle. Since gluconeogenesis involves the expenditure of energy, and this occurs in the liver rather than in the muscle, all the energy in the muscle can be used for muscle contraction.
L-Alanine possesses other properties, among them the ability to help maintain the health of the prostate. A study of benign prostatic hyperplasia (enlarged prostate) indicated that treatment with L-alanine, glutamic acid and glycine over a period of three months reduced the symptoms. However, make sure that you consult your physician before using alanine in this way. This is not because there are any known adverse side effects, because there are not, but because it I always wise to so with any supplement taken with a view to treating any medical condition.
A less obvious application derives from the fact that it forms a stable free radical when deaminated. Deamination can be initiated by radiation, and so the concentration of this free radical can be measured to ensure that the correct dose of radiation is being given in dosimetric radiotherapy. It is not always easy to control the dose accurately, and this property of alanine allows it to monitored and to ensure that it is neither too low to have the desired effect, nor dangerously high.
Although it is a non-essential amino acid, and can be produced by the body, a dietary supply or supplement is advantageous if extra energy is required. Good dietary sources of L-alanine include meats, seafood, eggs, nuts, beans, seeds, brewer's yeast, corn and legumes among others. Supplements are also available, and useful for body-builders, weightlifters and others involved in anaerobic exercise. Due to the glucose-alanine cycle, it can possibly provide energy when lactate build-up would otherwise lead to muscle cramps.
Those for whom a supplement could be useful are athletes and others who are trying to build muscle and stamina, or reduce their body fat and also the obese and overweight for the same reason. There is also evidence that a combination of the amino acids alanine, glycine and arginine can help to reduce arterial plaque from oxidized low density lipoproteins, and can also help to reduce high blood pressure.
Deficiencies are rare, although groups that do not eat meat should be careful to eat foods with a good alanine content. There are no known side effects of a deficiency since the body will generate what is needed for normal purposes, and while the supplement appears to have no side effects, it is advisable that pregnant and lactating women should first seek medical advice. The same applies if you suffer from hypertension or diabetes. High doses of alanine might also affect those with kidney or liver disease.
Although the benefits of supplementation of L-alanine might not be immediately obvious, the results and the science indicate that it is effective in making better use of blood glucose in that the adenosine triphosphate (ATP) created in the muscle tissue is allowed to be expended on muscle contraction while the glucose-alanine cycle provides the energy needed for gluconeogenesis.
June 11, 2008 04:51 PM
Multiple vitamins should be designed with one purpose in mind. They should provide you the ability to properly balance your regular diet with the additional vitamins, minerals, amino acids and antioxidants needed to make your diet nutritionally complete.
It is rare that people follow the recommended daily allowances in their regular diets. For this reason, multi-vitamins were developed to provide the missing nutrients to your daily diet. Vitamins designed with this purpose will automatically provide you with the essential additional nutrition you need to boost your health and wellness.
The Correct Multi-vitamin Make-Up:
A good multivitamin supplement will contain all of the following ingredients. It is designed to balance an average diet and boost health and wellness.
* Major vitamins * Minerals * Amino acids * Carotenoids * Tocopherols * Tocotrienols * Antioxidants
Antioxidants are an important part of any diet because they attack and neutralize free radicals. These fragments of chemicals are caused by:
* Normal metabolism * Pollution * Ultraviolet radiation * Rancid oil * Other toxins
Scientists believe that free radicals are one of the elements responsible for aging and degenerative diseases like Alzheimer's, arthritis and cancer. It is because of the nutrient deficiencies in our regular diets that we have become more susceptible to degenerative diseases.
Mixed Tocopherols and Tocotrienols:
Vitamin E is a series of related compounds. The four main forms are alpha, beta, delta and gamma. Most multi-vitamin supplements only contain large amounts of alpha tocopherol. A healthy diet needs a mixture of them all.
When too much alpha tocopherol is induced, gamma tocopherol is depleted. This causes deficiencies because gamma tocopherol is crucial to good health as well. For this reason, it is important that your tocopherol intake is balanced. A mixed intake of all tocopherols is more effective in preventing cardiovascular disease.
Tocotrienols are potent antioxidants that complement the alpha tocopherol. The combined nutrients are much more effective at preventing oxidation. This is why you must have a balanced combination of tocopherols and tocotrienols to maintain a healthy diet and a healthy body. To accomplish this you must have a balance of all of the compounds that make up vitamin E.
These are the red, orange and yellow plant pigments that are found in all of our fruits and vegetables. All of these contain different amounts of carotenoids, but the colors are often hidden by the plant's chlorophyll content. Examples of foods containing large amounts of carotenoids include:
* Kale * Collard greens * Swiss chard * Broccoli
Tomatoes contain Lycopene, which is a red carotenoid found in tomatoes. It is a potent antioxidant that reduces the risk of prostate cancer. Unfortunately, carotenoids are better absorbed through the ingestion of supplements than from foods. Multi-vitamins usually only contain beta carotene. It is important to find one that contains beta carotene, alpha carotene, lycopene, lutein and zeaxanthin.
The Bottom Line:
A complete multiple vitamin supplement is necessary as a part of a daily health and wellness regimen. The best multi-vitamin contains a healthy balance of everything listed above in the correct dosages. It is important to do your homework and be sure the multi-vitamin you choose will do its job correctly.
Learn as much as you can about your own body's individual nutritional needs. By giving your body proper nutrition, you help it to fight off illness and diseases much more efficiently. A complete multi-vitamin will:
* Strengthen your immune system * Decrease your risk of cancer, heart disease and osteoporosis * Increase your level of energy * Elevate your moods * Help you to enjoy a healthier, more productive life
Choose a multi-vitamin that has been developed based on the latest science and technology. You will be taking a well-rounded supplement that was designed to properly complement a typical daily diet.
About George’s and Warren Laboratories
April 21, 2007 01:58 PM
George Warren, and independent research chemist in Houston Texas, developed the special processing method that prevents the spoilage with out diminishing the essential properties of the Aloe Vera Plant. This new method completely eliminates the aloins, which gives a bitter taste (and the greenish color) to Aloe Vera juice. He also successfully removed the starches and sugars from the polysaccharide molecular chain and thus George’s “Always Active” Aloe requires no refrigeration, will not spoil in its natural state. This method adds no water, no preservatives, no chemicals of any kind. The finished product looks and tastes like spring water.
In 1965 George Warren began analytical chemical separation studies that led to the development of a procedure for separating aloe vera juice into 34 component parts. At the time plants in a commercial aloe vera field were numbered. Eight leaves from each plant were harvested. Bagged and labeled. The leaves were then chemically analyzed under laboratory conditions. The results of this testing concluded that six distinct groups were found, and for field testing, were designated as aloe plants A, B, C, X, Y, and Z. this procedure was used to analyze over 2,000 aloe vera plants and it was determined that the aloe vera field contained six different types of aloe vera plants. The chemical Make-Up of each plant fell into one of six aloe plant groups designated. Aloe-X exerted a very pronounced and measurable effect upon the digestive system. The ability of the digestive system to convert food to energy was greatly improved, but only when Aloe-X juice was consumed daily. The other aloe groups (A, B, C, Y, and Z) did not exert this effect. The improved digestion typified only by group X seemed to occur regardless of the type of digestive system. Listed below are Warren’s findings by daily consumption of Aloe-X.
During these animal feed experiments it was noted that in the control group the digestive system was often swollen and the animal’s hide and carcass did not appear to be healthy. In the Aloe-X test group this was very noticeably not the case. In fact, the digestive system, meat, hide and hair all seemed very healthy.
During the seven years of working with the farm animals the Aloe-X plants originally harvested were growing and multiplying. The chemical analysis of each plant-X offspring revealed that they indeed were only Aloe-X plants.
Up to this point, investigators found that aloe vera did not seem to always work. They were hindered by trying to correlate chemical structure to clinical performance. The primary and reasonable deduction for aloe vera not performing consistently was the fact that only Aloe-X had the ability to cleanse the membranes in the digestive system. If Aloe-X was not present in sufficient concentrations then the aloe vera juice did not seem “active” and did not perform.
Also noted was the phenomenal ability of the plant to quickly reduce swelling and bruised, swollen tissue. Thus, it is further hypothesized that Aloe-X exerts a pronounced effect on the digestive system, rejuvenation the tissue system. By making the digestive system work properly the body appeared to be capable of repairing itself and reverting back to a healthy state. Consequently, it is the firm and un-contradicted belief of Warren that allergies, asthma, emphysema, migraine headaches, and digestive problems are improved by Aloe-X through the membranes in the digestive system.
In the early stages of experimentally using Aloe-X, it was noted that other chemical compounds were present which should not be consumed on a regular basis. In fact, the work of the University of California Professor Bruce Ames clearly points out that all plants have their own toxin defense system against predators. Therefore, not all chemical compounds of plants are good for your health. With this thought in mind, standard conventional pharmaceutical chemical engineering principles were used to remove many undesirable components. Aloe vera by nature spoils easily requiring preservatives to be added to most commercial brands to extend the shelf life of the product. This short shelf life has consistently been a problem for the exploitation of the many benefits of this remarkable plant. Thus, in Warren’s products, starches and sugars of the mucopolysaccharide molecular chain have been removed. These starches and sugars act as an energy source for undesirable micro-organisms. Several other components which earlier testing revealed to be undesirable have also been removed. These substances are removed by a proprietary purification and filtering method. Consequently, preservatives are not required. The micro0organisms picked up in the processing and handling are removed immediately prior to packaging. Testing performed by Warren supports its finding that the purification system does not destroy the active components in the company’s aloe products. Such tests, as well as the votes of confidence (indicated by the thousands of humans and confirmed by testing on chickens, pigs, birds, cows, horses, fish, dogs and cats) confirm that findings. Warren has been successful in developing and proving a unique fractional distillation process that allows for capturing the therapeutic benefits of Aloe Vera.
April 09, 2007 05:02 PM
EpiCor® is a unique and novel dietary supplement used for support of immune health, with a fascinating history of discovery. In 1943, a company in
Interestingly, when the company became self-insured, they became aware of unusually low rates of illness in employees that worked in the manufacturing plant for this animal product. This led to very low increases in their insurance premiums over the years compared to other companies, saving them quite a lot of money. Hence they began to investigate what might be the cause of the “healthfulness” of the employees at the fermentation plant. This investigation and subsequent research studies led to the formation of a new company called Embria Health Sciences, which now produces EpiCor® as a supplement for humans to support immune system health.1 Doctor’s Best® is proud to now offer the benefits of EpiCor® to its customers.
Beneficial Support of the Immune System and Activation of Natural Killer (NK) Cells in vitro*
A comparison study was performed on blood from 10 fermentation plant workers compared to that from 10 age and gender matched controls. The fermentation plant workers had several immune cell parameters that appeared superior to the control group. These included decreased levels of CD8 cells resulting in significantly increased CD4 to CD8 ratios, significantly improved cytotoxic natural killer (NK) cell activity even though total NK cells were decreased in number, higher killing efficiency of NK cells, significantly increased levels of secretory IgA, increased numbers of EpiCor™ specific antibodies, higher levels of red blood cell intracellular glutathione, and significantly lower levels of immune complexes. These results represent benefits on various cellular players of both the specific and innate parts of the immune system.1,3,4
NK cells are one of the first lines of defense used by the immune system. An in vitro study performed on human cells showed that NK cells were activated after incubation with EpiCor®, as evaluated by expression of the CD69 activation marker. The CD25 marker (IL-2 receptor) was also induced in the NK cells, although to a lesser degree.1,2 B cell activation was also noted through increased expression of CD80 and CD86 markers.2 Immediate increases in calcium levels were evident in peripheral blood mononuclear cells after exposure to EpiCor®, suggesting increased activation through calcium regulation.2
High Metabolite Immunogen*: Nutrient Make-Up
Production of EpiCor® utilizes the common and harmless bakers or brewers yeast Saccharomyces cerevisiae in a patented process called MetaGen4™, a multi-stage fermentation and drying process. It differs from other yeast products in that it contains both the yeast itself as well as the metabolites or “nutrilites” formed by the fermentation process, which are present in the media.1 Together the media containing the metabolites and the yeast are dried to form EpiCor®. Analysis of EpiCor® reveals that it contains a mixture of natural polyphenols, phytosterols, beta-glucans, mannan oligosaccharides, fiber, trace amounts of B vitamins and minerals, as well as a host of other nutritional compounds.1,2
Beneficial Antioxidant Activity*
EpiCor® was tested for antioxidant activity in an in vitro assay called the Oxygen Radical Absorbance Capacity assay (ORAC). In this assay, EpiCor® was shown to have a total ORAC antioxidant level of 610 micromol TE (tocopherol (vitamin E) equivalents) units (ORAC units) per gram dry weight, which soared above other high antioxidant level foods such as cranberries (93 ORAC units per gram dry weight) and blueberries (62 ORAC units per gram dry weight).1,3,5
In another study, freshly isolated human neutrophils were treated with EpiCor® followed by the free radical generator hydrogen peroxide. Cells were treated with a dye that fluoresces when attacked by free radicals. Those cells treated with EpiCor® showed decreased fluorescence intensity compared to control cells not treated with EpiCor®, verifying antioxidant activity in vitro.2
Numerous safety tests have been conducted on EpiCor®, revealing an extremely safe profile. Animal studies performed by a leading toxicology laboratory showed no indication of any toxic effects of EpiCor®. An acute oral toxicity study on 20 rats showed that the product was safe when given to rats at a single oral dose of 2000 milligrams per kilogram of body weight (equivalent to a human ingesting 280 capsules at once). After 2 weeks the rats showed no clinical symptoms, no deaths, no abnormalities in body weight, and no gross pathological changes. The same safety results were found in a subchronic toxicity study where rats were given up to 1500 milligrams daily for 90 days (equivalent to a human ingesting up to 210 capsules daily for 1.5 years). Again, absolutely no signs or symptoms of toxicity were noted in these animals.1,3
In addition, a standard bacterial reverse mutagenicity test (AMES test) as well as a mammalian cell mutation assay using mouse lymphoma cells revealed no evidence of any increase in mutation rates after exposure to EpiCor®. EpiCor® also showed no evidence of mitogenicity (inducing increased cell division) in a human lymphocyte proliferation assay. This suggests that EpiCor® does not cause over-reactivity of cells1,3.
The effect of EpiCor® on specific liver enzymes CYP1A2 and CYP3A4 (enzymes involved in metabolizing certain drugs and other compounds) was assessed. Immortalized hepatocytes (liver cells) were treated with various concentrations of EpiCor® and compared to both positive and negative controls. EpiCor® did not increase the expression or activity of the liver enzymes, suggesting that it may not affect the metabolism of other substances or medications metabolized by these enzymes if they are taken simultaneously. It also did not appear to be toxic to the cells as measured by lactate dehydrogenase assays and microscopic analysis.1
Lastly, EpiCor® was tested for safety in humans in an open label study on 15 adult men and women given a single 500 milligram dose for 30 days. On various days throughout the study vital signs were monitored, and blood and urine samples were analyzed. No clinically relevant abnormal effects on the participants were found1.
EpiCor® also currently has received self-affirmed Generally Regarded as Safe (GRAS) status by an expert panel that included eminent toxicologists1.
EpiCor® is a novel compound with an incredibly unique composition that has been shown to enhance immune system function.*
Suggested Adult Use: Take one capsule daily with or without food.
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
1. Embria Health Sciences
2. Hart et al. A new Saccharomyces cerevisiae based product has anti-inflammatory effects while specifically activating human NK and B lymphocyte subsets. Unpublished study, personal communication.
3. Schauss AG, Jensen G, Vojdani A, Financsek I. After decades of ingestion by farm animals, the discovery of a yeast fermentate with unexpected significant immune modulatory activity when consumed by humans. [abstract] Journal of the
4. Schauss AG, Vodjani A. Discovery of an edible fermentation product with unusual immune enhancing properties in humans. [abstract] FASEB J, 2006; 20(4):A143.
5. Wu X, Beecher GR, Holden JM, Haytowitz DB, Gebhardt SE, Prior RL. Lipophilic and hydrophilic antioxidant capacities of common foods in the
Basics of the Immune System
June 10, 2005 03:01 PM
Basics of the Immune System
by Leonid G. Ber, MD Energy Times, September 1, 1998
In a world filled with pathogens and microbes, good health and resistance to disease is no accident. It requires a vigorous and vigilant immune system. The immune system should be viewed as an internal security force that is constantly checking the identity of everything entering and already existing in the body. A cell or substance may be recognized as "non-self" and a potential enemy if it does not have the right molecular Make-Up. A cell displaying molecules produced according to a different blueprint than the body's own code may be recognized as foreign. To eliminate alien material that may harm the body, the immune system must take swift action.
Recognizing entities that originate outside the self forms the key to overall immune system response. This key is carried in the body by cells called macrophages (ma-kro-fajs), a name derived from a Greek term meaning "big eater." Macrophages eat or engulf foreign cells and molecules. When a macrophage encounters something that it distinguishes as being "non-self" or abnormal, it can attack the enemy with a series of assault weapons, including free-radicals (reactive substances) and enzymes, that dissolve and weaken the intruder. In fact, an enzyme produced by macrophages called lysozyme is recognized as one of nature's most powerful anti-infective agents. These chemical defenses, along with engulfment and complete digestion by macrophages, can effectively stymie invasion by disease-causing pathogens.
Harmful invasion can originate in the body's own cells as well as begin from outside sources. While we are constantly exposed to bacteria, viruses, fungal cells and parasites, destructive cancerous growths often start within the body.
Every day, thousands of the body's cells mutate into possible cancers. Under most circumstances, the immune system keeps these cells under control. But when the immune "security" system slips up, these harmful growths multiply unrecognized.
The initial immune response that recognizes invaders is called a "non-specific defense mechanism" since this immune response is generally the same toward all invaders. This counter-attack entails battling every invader pretty much identically: a macrophage can engage, dissolve, weaken, engulf, digest, eliminate. However, if, despite the initial immune efforts, the problem persists, a macrophage can tag an invader and "introduce" it to the rest of the immune system, thus recruiting more specialized types of immune cells to enter the battle. This tagging function endows macrophages with the name "antigen-presenting cells." (Antigens are substances that can provoke specific responses by the immune system.)
Most antigens are proteins. Proteins are relatively large molecules made of smaller units called amino acids. The specific geometric organization of amino acids is what conveys uniqueness to each protein. (Your genetic code forms a blueprint for the production of your own, individual proteins.) Protein molecules produced by one human being can act as an antigen for another human being. That's why organs transplanted from one person to another can be rejected by the immune system. Unless organs are transplanted from one identical twin to another (who share the genetic blueprint for protein creation), doctors must use immune-suppressing drugs to curtail organ rejection. At the same time as these medicines prevent transplant rejection, they also make people more susceptible to infectious diseases and cancer.
After one set of immune cells chemically tags antigens (invaders) for recognition, other highly specialized parts of the immune system go into action: Cells called T cells or T lymphocytes acknowledge the invaders and can take the further action (second line of defense) that is necessary to render them harmless.
T cells get their name from the thymus (an organ located behind the sternum) where they originate. The thymus, most active when we're young, usually shrinks and apparently slows or shuts down its activity about the age of forty.
A wide variety of T cells inhabit lymph nodes (soft, usually round, pea- or nut-sized organs) and other body areas. For instance, natural killer cells, as their name implies, are a particularly aggressive type of T cell. Another type of T cell is called T helper (a cell that supports development of immune response). T suppressors halt immune response when infection ends.
In order to make all these different cells work in concert, cytokines or messenger molecules are produced that facilitate constant communications between all the parts of the immune system.
The B Team
Other organs of the immune system include:
*bone marrow: a powerful cell producing organ where the majority of immune cells are born;
*spleen: an abdominal organ that forms a reservoir for the production of immune cells.
Lymph nodes oversee particular segments of the body where they collect and recycle tissue fluids. Like an early warning system, lymph nodes react when an invader is detected in the part of the body that it controls.
Yet another step in the so-called immune cascade entails action by lymphocytes, called B cells, which originate in the bone marrow. These cells produce antibodies which are immune proteins (immunglobulins) that attack specific antigens.
While traveling in the blood, an antibody can bind to an antigen, curtailing its harmful action. This bound up molecule forms a complex easily recognized by scavenging macrophages which make a quick meal out of the unlucky invader.
After enemy cells are removed from the body, knowledge of this victory resides in the immunological memory prolonging your resistance toward specific disease pathogens indefinitely. That's why someone who has recovered from a disease like the measles may be impervious to reinfection.
Rules for Optimum Immunity
Even though the immune system consists of a complex team of hard-working cells, enhancing your immunity is relatively easy:
Maintain a healthy lifestyle. Avoid continuous stress and negative emotions or cope with them through exercise or meditation. Consistent, moderate exercise can boost the immune system. Massage can also help although extreme care must be taken when inflammation or disease is already present.
Sleep 7-8 hours a day. Sleep allows the body to recover and rebuild. Protein synthesis, vital for a healthy immune system, increases during the night.
Stick to a healthy diet. Your immune system consists of trillions of cells. Consequently, nutrients important for cell health boost the immune system. A balanced low-calorie diet rich in complex carbohydrates, "good" fats (including fish oils, olive oil and flaxseed oil) along with vitamins, minerals and phytonutrient antioxidants from fresh fruits and vegetables can fortify immune cells. Plus, drinking plenty of water helps improve circulation of lymph fluid.
These recommendations are not hard to meet once they become a part of your daily routine. However, extra immune security may be necessary during flu season, while traveling long distances (airplanes are notorious sources of pathogens) or when working extensive hours in front of a computer screen. In addition, exposure to x-rays, immunosuppressive chemicals, ultraviolet radiation (the sun) or simply aging may give your immune cells extra burdens.
Your "specific" immune system does not respond immediately to the challenge of invasion by an infectious organism. Instead, it may require about 2 weeks for an effective reaction after antigen recognition and alerting T cells. During this period, the macrophages' non-specific defense assumes a crucial role in keeping infection in check.
Enhanced activity by macrophages is especially important for recognizing and destroying cancer cells. The most dangerous cancers are those that can mimic normal cells and avoid the immune system's wrath. Few substances can activate macrophage function in the body (aloe vera contains substances that contribute to this process). The most powerful macrophage activator recognized by the scientific community is a sugar-like substance called beta-1,3-D-glucan. Beta-glucan, extracted from the cell walls of common Baker's yeast, when taken in certain small amounts, can prevent infection by making macrophages more active in recognizing and attacking infectious bacteria, fungi and certain viruses.
This kind of activation can encourage macrophages to attack previously unrecognized tumor cells. As a result, tumors may be eradicated as the immune system mobilizes and produces what may be known as "spontaneous healing."
When a macrophage works overtime fighting disease, its demand for nutrients and energy increases dramatically. Vitamin C, known for its immune supporting function, seems to be especially important for maintaining fully active macrophages. Vitamin C collects in macrophages, often reaching forty times the concentration found in surrounding blood. What are conventionally considered normal amounts of vitamin C in the body may be insufficient to keep macrophages well supplied with this antioxidant. Therefore, extra amounts of vitamin C can keep the immune system in fighting trim.
Scientists are only now beginning to uncover the secrets of the highly organized immune system. One thing's certain: The immunity security team depends on proper lifestyle, nutrition and supplements to maintain the critical defenses necessary for good health.
Dr. Ber received his doctorate in internal medicine from the Yaroslavle, State Medical Institute in Yaroslavle, Russia.