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Largest Human Clinical Study Confirms Aged Garlic Extract's Ability to Reduce Cancer Risk
June 09, 2005 05:26 PM
Largest Human Clinical Study Confirms Aged Garlic Extract's Ability to Reduce Cancer Risk Factors Presented at the 2005 World Garlic Symposium at Georgetown
Garlic has been used medicinally for thousands of years. Past research has established the significance of garlic and its healthful benefits. Recently new metabolic roles for garlic were presented at the symposium, “Significance of Garlic and its Constituents in Cancer and Cardiovascular Disease” which was held at the Georgetown University Conference Center on April 9-11, 2005.
The conference brought together the world’s top authorities in various fields of garlic research to provide the latest updates, specifically regarding aged garlic extract and its actions in diseased states such as cancer.
One of the highlight presentations was on the biggest study ever conducted in the history of garlic supplementation, a 7 year long clinical study. The study was undertaken to determine aged garlic extract effects on stomach cancer and serous digestive problems that can lead to gastric cancers. It was performed through collaboration of National Cancer Institute (NCI) and leading Chinese researchers, who tested to see if aged garlic supplementation would significantly effect or reduce precancerous gastric lesions. The clinical study was double-blinded and randomized, with over 3,000 human subjects. It was led by Dr. Mitchell Gail at NCI and Dr. Wei-Cheng You at the Beijing Institute for Cancer Research.
Preliminary results of this study showed that people with the highest intake of allium-containing vegetables, like aged garlic, had only 40% of the risk of gastric cancers as those who rarely ate them.
Also from the Chinese study was another surprising finding: when researchers used aged garlic extract in combination with antibiotics to treat people with precancerous stomach lesions caused by the Helicobacter pylori bacteria, 76% were completely healed. “It’s a very large and long-term study. We’re still sifting though the data, but we expect to report on it by the end of this year,” said Dr. Gail.
Another surprising presentation showed the results of several colon cancer studies reported from both Osaka and Hiroshima University in Japan. These studies clearly showed that the addition of aged garlic extract to cancer treatment was beneficial to colon cancer patients. Researchers found that those who consumed aged garlic extract experienced a reduction of the size and prevalence of tumors.
“Aged garlic extract has well-known antioxidant properties. The aging process eliminates garlic breath as well as those harmful properties, leaving only the antioxidants that protect against disease,” said cancer symposium chairperson and lead UCLA researcher David Heber, M.D.
Almost 400 scientific studies have been completed on aged garlic extract, done in major universities worldwide. These studies have focused on a variety of heart disease risk factors such as cholesterol, high blood pressure, homocysteine levels, inhibiting LDL oxidation, anti-platelet aggregation and adhesion, stimulating blood circulation; in addition to other studies on immune stimulation, cognitive effects, liver function and anti-tumor effects.