Solaray Multidophilus 12: Advanced 12-Strain Gut & Immune Support
Your digestive tract is home to tens of trillions of microorganisms known as your gut microbiome. When diet, travel, daily stress, or antibiotics disrupt this delicate ecosystem, you may experience occasional bloating, sluggish digestion, or weakened immune defenses. Solaray Multidophilus 12 delivers a potent, broad-spectrum blend of 20 billion CFU (Colony Forming Units) across 12 clinically researched probiotic strains to replenish beneficial flora, improve nutrient uptake, and keep your digestion running smoothly.
Key Product Highlights:
✓12 Targeted Strains: Balances both the small intestine (with Lactobacillus) and the colon/large intestine (with Bifidobacterium).
✓20 Billion Guaranteed CFU: Live cultures formulated to restore microflora diversity.
✓Enteric Shield™ VegCaps: Acid-resistant capsules protect sensitive bacteria from stomach acid so they reach the intestines alive.
✓Fuelled by Prebiotic Inulin: Natural soluble chicory root fiber that actively nourishes the friendly bacteria.
✓Clean & Tested: Non-GMO, 100% dairy-free, and lab-tested for potency, heavy metals, and purity.
Why 12 Strains? The Science of Microbial Diversity
Many basic probiotics only provide one or two bacterial strains. However, your gut naturally thrives on a diverse mixture of organisms that work in different parts of your body:
1. Small Intestine Specialists (Lactobacillus)
Strains such as L. acidophilus, L. plantarum, L. rhamnosus, L. casei, L. brevis, L. bulgaricus, and L. salivarius colonize the upper digestive tract. They produce lactic acid and natural enzymes, helping break down foods, reduce occasional gas, and discourage unwanted microbes from taking hold.
Strains like B. lactis, B. bifidum, B. longum, and B. infantis inhabit the large intestine (colon). They assist with bowel regularity, ferment dietary fiber into short-chain fatty acids (which nourish your gut lining), and support overall digestive comfort.
3. Synergy & Immune Support (Streptococcus thermophilus)
Streptococcus thermophilus works hand-in-hand with Lactobacillus to ferment dairy sugars (lactose), produce beneficial enzymes, and stimulate mucosal immune defenses within the gut-associated lymphoid tissue (GALT).
The Enteric Shield™ Difference: Surviving Harsh Stomach Acid
The biggest challenge with live probiotics is survival. Your stomach contains strong gastric acid (pH 1.5 to 2.5) designed to break down food and destroy foreign bacteria. Unfortunately, ordinary gelatin or standard vegetable capsules dissolve in the stomach within minutes, killing a large percentage of live probiotic cultures before they ever reach the intestines.
Solaray Multidophilus 12 solves this with Enteric Shield™ VegCaps:
Acid Armor: Enteric-coated plant capsules remain intact while passing through the acidic gastric environment of the stomach.
Targeted Release: Once the capsule moves into the neutral pH environment of your small intestine, the coating dissolves smoothly, releasing all 20 billion living organisms right where they are needed most.
Built-in Fuel (Inulin): Every serving includes prebiotic inulin, a dietary fiber that serves as the preferred food source for probiotics, ensuring the good bacteria can feed, thrive, and colonize effectively.
Complete Supplement Facts & Ingredients
Full formula transparency. Contains zero artificial colors, artificial flavors, preservatives, or dairy ingredients.
Supplement Facts
Serving Size: 2 Enteric VegCaps Servings Per Container: 50
Amount Per Serving
% Daily Value
Total Carbohydrate <1 g
<1%†
Dietary Fiber <1 g
2%†
12-Strain Probiotic Blend (1 g)
Supplying 20 Billion CFU** of live organisms: B. lactis, B. bifidum, B. infantis, B. longum, L. acidophilus, L. brevis, L. bulgaricus, L. casei, L. plantarum, L. rhamnosus, L. salivarius, Streptococcus thermophilus
*
† Percent Daily Values are based on a 2,000 calorie diet.
* Daily Value not established.
** Minimum potency at time of manufacture. Live organisms per 2 capsule serving.
Other Ingredients: Inulin, Vegetable Cellulose Capsule, Organic Rice Extract Blend, and Silica.
Handling living cultures requires care. Drawing from over 30 years of retail supplement experience, here are our essential recommendations to ensure you get maximum potency from every bottle:
✓ How to Take for Maximum Results
Take 2 Enteric VegCaps daily with a full glass of water. While the enteric coating protects the cultures from stomach acid, taking them with a light meal or 20 minutes before breakfast helps ensure smooth transit into the intestines.
✓ Taking Probiotics with Antibiotics
Never swallow probiotics at the exact same time as your antibiotic pill. Antibiotics kill beneficial bacteria alongside harmful ones. Allow at least a 2-hour window between your antibiotic dose and taking Multidophilus 12 to safeguard the live organisms.
✓ Refrigeration & Ice Pack Shipping
Keep Refrigerated: Multidophilus 12 stays fresh and potent when kept in your refrigerator. During transit, short-term exposure to ambient temperatures will not destroy the bacteria, but for optimal protection during warm summer months, we strongly recommend adding an ice pack to your order at checkout.
Scientific Evidence & Clinical Backing
Our formulations and educational claims are evaluated against peer-reviewed clinical research:
Multi-Strain Synergy Over Single Strains: Clinical reviews show that multi-strain probiotic blends often provide broader antimicrobial defense and superior gut mucosal adherence compared to single strains alone. Reference: Chapman, C. M., et al. (2011). "Parasitology and gut microbiome: Design and efficacy of multi-strain probiotics." European Journal of Nutrition, 50(1), 1–17. [PMID: 21229254]
Enteric Protection from Gastric Degradation: In vitro simulations demonstrate that unprotected probiotic species suffer up to 90% or greater loss of viability when exposed to gastric juice at pH 2.0 within 60 minutes, confirming the necessity of targeted enteric encapsulation. Reference: Cook, M. T., et al. (2012). "Microencapsulation of probiotics for gastrointestinal delivery." Journal of Controlled Release, 162(1), 56–67. [PMID: 22698933]
Prebiotic Inulin & Short-Chain Fatty Acid Production: Inulin is proven to selectively stimulate the growth of Bifidobacterium species, elevating intestinal butyrate and acetate levels which maintain the gut barrier. Reference: Gibson, G. R., et al. (2017). "Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics." Nature Reviews Gastroenterology & Hepatology, 14(8), 491–502. [PMID: 28611480]
Spacing Probiotics During Antibiotic Therapy: Studies indicate that co-administration of probiotics reduces the incidence of antibiotic-associated diarrhea (AAD) when spaced 2 to 3 hours apart from antibiotic medication. Reference: Hempel, S., et al. (2012). "Probiotics for the prevention and treatment of antibiotic-associated diarrhea: a systematic review and meta-analysis." JAMA, 307(18), 1959–1969. [PMID: 22570464]
*Disclaimer: Statements made on this page have not been evaluated by the Food and Drug Administration. This product is a dietary supplement and is not intended to diagnose, treat, cure, or prevent any disease. Always consult your healthcare practitioner before beginning any new nutritional program.
Frequently Asked Questions About Solaray Multidophilus 12
What makes Multidophilus 12 different from regular probiotics?
Unlike single-strain products, Solaray Multidophilus 12 combines 12 distinct probiotic strains (providing 20 billion CFU) to support both the small and large intestines simultaneously. Furthermore, its Enteric Shield™ vegetable capsules shield live organisms from destructive stomach acids, ensuring they survive transit into your gut.
Does Solaray Multidophilus 12 require refrigeration?
Yes. For maximum stability and to maintain the full 20 billion CFU potency through the expiration date, this product should be kept refrigerated after opening. While short transit times at room temperature are tolerated, we offer add-on cold ice packs during checkout for warm-weather delivery.
How and when should I take Multidophilus 12?
The recommended serving size is 2 Enteric VegCaps daily with a full glass of water. They can be taken with a light meal or shortly before eating. If you are currently taking prescription antibiotics, separate your probiotic dose by at least two hours.
Is this probiotic dairy-free and gluten-free?
Yes, Solaray Multidophilus 12 is 100% dairy-free, vegetarian, and non-GMO. It contains no artificial colors or flavors, making it suitable for individuals with lactose intolerance or dairy sensitivities.
Why is inulin included in the ingredients?
Inulin is a prebiotic soluble plant fiber sourced from chicory root. It acts as essential nutrition for the beneficial bacteria in your digestive tract, helping the live probiotic strains settle, reproduce, and produce health-promoting short-chain fatty acids.