Solaray Multidophilus 12: Broad-Spectrum 20 Billion CFU Probiotic Support
Solaray Multidophilus 12 is an advanced, high-potency digestive formula delivering over 20 billion living organisms from 12 clinically investigated probiotic strains in every 2-capsule serving. Engineered with an acid-resistant Enteric Shield™ and fortified with prebiotic inulin fiber, this 12-strain formula is designed to bypass harsh stomach acid and arrive alive where you need it most: your small and large intestines.
Why 12 Strains Matter: Complete Small and Large Intestinal Coverage
Think of your digestive tract as a bustling ecosystem, home to trillions of microorganisms collectively known as the gut microbiome. Different sections of your digestive tract require different types of beneficial bacteria to function comfortably:
The Lactobacilli Group (Upper Gut & Small Intestine): Strains such as L. acidophilus, L. plantarum, and L. rhamnosus thrive in the small intestine. They convert lactose and plant sugars into lactic acid, creating an acidic environment that keeps undesirable microbes from taking over while supporting seamless nutrient absorption.
The Bifidobacteria Group (Lower Gut & Colon): Strains like B. lactis, B. bifidum, and B. longum make up the vast majority of healthy bacteria in the large intestine. They ferment prebiotic plant fibers into short-chain fatty acids (SCFAs) like acetate and butyrate, which serve as primary fuel for your intestinal lining cells.
Streptococcus thermophilus (Digestive Comfort & Motility): A transient lactic acid producer that helps break down dairy sugars, eases post-meal fullness, and works symbiotically alongside Lactobacilli to maintain steady intestinal transit.
By combining 12 distinct strains rather than just one or two, Solaray Multidophilus 12 helps restore microbial diversity after dietary stress, seasonal changes, or antibiotic use.
The Enteric Shield™ Advantage: Protecting Bacteria from Stomach Acid
A probiotic is only effective if its live cultures survive the journey through your digestive system. Human stomach acid is extremely acidic (pH 1.5 to 3.0), which naturally kills many raw, unprotected bacteria before they ever reach the intestines.
Solaray solves this with specialized Enteric VegCaps:
1. Stomach Acid Protection: The enteric shell remains intact while submerged in acidic gastric fluid, shielding the delicate live bacteria inside from premature destruction.
2. Targeted Intestinal Release: Once the capsule transitions into the neutral-to-alkaline pH of the small intestine (pH 6.5 to 7.5), the coating safely dissolves, releasing 20 billion active cultures directly onto the mucosal surface.
3. Built-In Prebiotic Inulin: Each serving contains inulin, a soluble chicory root fiber that acts as immediate nourishment for the newly arrived probiotics, speeding up colonization and digestive balance.
† Percent Daily Values are based on a 2,000 calorie diet.
* Daily Value not established.
** Minimum potency guaranteed at the time of manufacture.
Other Ingredients: Inulin (from Chicory Root), Vegetable Cellulose Capsule, Organic Rice Extract Blend, and Silica. Free Of: Dairy, gluten, soy, artificial colors, and artificial flavors. 100% Vegan & Non-GMO.
How to Take Multidophilus 12: Expert Retail Protocol
For over 30 years helping customers choose and use digestive supplements, we have found that following three simple rules delivers the best results:
Daily Serving: Take two (2) Enteric VegCaps once daily with an 8-ounce glass of room-temperature water. While the enteric coating protects bacteria at any time, taking them right before a meal can further aid comfortable transit.
The 2-Hour Antibiotic Window: If you are taking prescription antibiotics, do not swallow your probiotics at the same time. Antibiotics will eliminate both good and bad bacteria. Take your Multidophilus 12 at least two hours before or two hours after your medication.
Refrigeration & Storage: Keep your bottle refrigerated after opening to preserve the maximum CFU count. Multidophilus 12 is formulated to remain stable during short-term shipping without cold packs, but placing it in your home refrigerator upon arrival helps ensure all 20 billion organisms remain active through the expiration date.
Clinical Science & Peer-Reviewed References
Our product evaluations and educational guides are based on published clinical research in gastroenterology and human microbiology:
Probiotic Definition & Health Consensus: Hill, C., et al. (2014). "The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the scope and appropriate use of the term probiotic." Nature Reviews Gastroenterology & Hepatology, 11(8), 506–514.
Epithelial Barrier Function: Sanders, M. E., et al. (2019). "Probiotics and prebiotics in intestinal health and disease: from biology to the clinic." Nature Reviews Gastroenterology & Hepatology, 16(10), 605–616.
Synbiotic Mechanics & Inulin Fermentation: Gibson, G. R., et al. (2017). "Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics." Nature Reviews Gastroenterology & Hepatology, 14(8), 491–501.
Capsule Gastric Survival: Terpou, A., et al. (2019). "Prebiotics, Probiotics, Synbiotics: Delivery systems and survival through gastric transit." Microorganisms, 7(11), 509.
Frequently Asked Questions (FAQ)
Does Solaray Multidophilus 12 need to be refrigerated during shipping?
Solaray crafts Multidophilus 12 with extra live organisms to withstand normal shipping transit times without losing potency. However, to keep the 20 billion cultures healthy over months of storage, you should store the bottle in your home refrigerator once it arrives. Customers in high-heat summer climates may also select an optional ice pack during checkout.
What does "Enteric Coated" mean and why is it important?
"Enteric coated" means the capsule is wrapped in a specialized plant shield designed to withstand strong stomach acid. The capsule does not dissolve in the stomach; instead, it travels safely into the neutral environment of the small intestine before opening, ensuring the probiotic bacteria arrive alive where they can colonize and support digestion.
Can I take Multidophilus 12 while taking antibiotics?
Yes, taking probiotics during and after antibiotic regimens helps maintain gut balance and reduces temporary digestive upset. However, to prevent the antibiotic from wiping out the beneficial bacteria in your supplement, always separate your probiotic dose by at least two hours before or after your antibiotic medication.
Is Solaray Multidophilus 12 dairy-free and vegan?
Yes. Although strains like Lactobacillus bulgaricus are historically associated with cultured dairy foods, Solaray cultivates these organisms on dairy-free vegetable growth mediums. The capsule is made entirely of vegetable cellulose, making the finished product 100% dairy-free, vegan, and non-GMO.
How long does it take to experience the benefits of Multidophilus 12?
Many people notice improvements in routine digestion, gas, and abdominal bloating within 3 to 7 days of daily use. For full intestinal lining reinforcement, improved regularity, and balanced nutrient absorption, daily supplementation for 2 to 4 consecutive weeks is recommended.
Safety & Compliance Notice: Keep your licensed healthcare practitioner informed when using this product. Do not use if safety seal is broken or missing. Keep out of reach of children. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
As a dietary supplement, take 2 capsules daily with a meal or glass of water.
