NOW: L-Citrulline 750mg 180 Caps

L-Citrulline 750mg - 180 Caps



by   NOW FOODS
*MSRP:
$49.99
Our Price:
$30.00
Buy: at $30.00
(3 for $ 29.99ea. = $ 89.97 ) 40% OFF MSRP
UPC: 733739001030
# N0103

Product Overview & Quick Specs

Think of your blood vessels like flexible garden hoses that must stay wide and supple. When vascular walls relax, nutrient-rich blood flows effortlessly to your heart, brain, and working muscles. NOW Foods L-Citrulline 750 mg delivers pure, free-form amino acid nutrition designed to fuel your natural nitric oxide pathways. Each vegetarian capsule provides flexible, gentle circulatory support and muscular recovery in an easily absorbed format.

  • ✓ Active Form & Potency: Delivers 1.5 g (1,500 mg) of pure, free-form L-Citrulline per 2-capsule serving (750 mg per vegetarian capsule).
  • ✓ Primary Target: Fuels systemic nitric oxide synthesis, promotes arterial relaxation, and supports liver urea cycle waste clearance.
  • ✓ Supply & Value: 180 vegetarian capsules supply 90 full servings per bottle, offering customizable dosing and high cost efficiency.
  • ✓ Purity & Dietary Status: Non-GMO, vegan-friendly, and verified free of gluten, soy, dairy, egg, fish, shellfish, tree nuts, and sesame.

Buyer's Guide & Form Comparison

Many sports pre-workout formulas use "citrulline malate" powders. Those formulas chemically bond citrulline with malic acid, meaning you often receive only 50% to 67% actual citrulline by weight. Bulk malic acid powders can also trigger sharp stomach acidity and heartburn. Other products rely on regular L-arginine, which digestive enzymes break down before it reaches systemic circulation. NOW Foods L-Citrulline 750 mg delivers 100% pure, free-form amino acid inside smooth vegetarian capsules. Cheap commodity discount brands found in big-box stores often hide synthetic binders and industrial impurities. NOW Foods tests every batch to guarantee verified purity without digestive distress.

Best Choice For:

  • ✓ Athletes and fitness enthusiasts seeking stimulant-free muscle pumps, sustained workout stamina, and faster recovery.
  • ✓ Adults looking to support healthy arterial elasticity, vascular tone, and optimal everyday blood circulation.
  • ✓ Shoppers who prefer adjustable, incremental 750 mg capsule dosing rather than drinking sour, chalky powders.

Consider Another Option If:

  • ✗ You prefer mixing unflavored bulk powder into large workout drink bottles rather than taking capsules.
  • ✗ You currently take prescription nitrates or blood pressure medications and have not yet consulted your physician.
  • ✗ You are looking for an intense sensory stimulant rush from added caffeine or artificial energy stimulants.

VitaNet®, LLC has served health-conscious shoppers since 1995 with 31+ years of supplement curation, backing every purchase with an unconditional 100% money-back guarantee—even on opened bottles.

How It Works in the Body

Think of standard oral arginine like a delivery truck stuck at a congested highway toll booth. When you swallow regular arginine, gut and liver enzymes destroy up to 70% of it before it reaches your bloodstream (first-pass intestinal and hepatic arginase metabolism) [1]. In contrast, think of L-Citrulline like an express train running on a dedicated express track. It bypasses liver breakdown entirely and enters your systemic bloodstream intact [1].

Now think of your kidneys like a specialized manufacturing workshop. Once absorbed, your kidneys convert L-citrulline directly into fresh L-arginine using two internal enzymes (argininosuccinate synthetase and argininosuccinate lyase) [2]. This conversion creates higher, longer-lasting blood levels of arginine than swallowing arginine pills directly [1]. Your vascular lining (endothelium) uses this steady supply to generate nitric oxide gas [1]. Nitric oxide commands arterial walls to soften and expand (vasodilation) [1]. This widening allows oxygen and nutrients to reach working muscle tissues swiftly [3].

Picture intense exercise like running an automobile engine at maximum speed. Heavy physical contractions produce harsh chemical exhaust in the form of metabolic ammonia (NH3) [4]. When ammonia accumulates, muscle cells fatigue and burn [4]. L-Citrulline functions as an essential gear in your body's cellular waste treatment facility (the urea cycle) [2]. It binds with waste compounds to convert toxic ammonia into harmless urea [2]. Your kidneys then safely flush this urea out through your urine, helping active muscles recover smoothly [2, 4].

Daily Timing, Synergy & Realistic Timelines

Best Time to Take: Think of the absorption gateways in your gut like a single turnstile entrance. If you take free-form amino acids with heavy protein meals, thousands of dietary protein fragments crowd the doorway. Taking your capsules on an empty stomach with a full 8 ounces of water or fruit juice ensures rapid, unhindered absorption.

Daily Schedule: Take 1 to 2 capsules 1 to 2 times daily. For athletic workouts and training pumps, take 2 to 4 capsules (1,500 to 3,000 mg) 45 to 60 minutes before exercise. On rest days or for cardiovascular support, take 1 to 2 capsules in the morning, and an optional second dose in the afternoon between meals.

Smart Pairings & Spacing: You can stack L-Citrulline with Vitamin C or Glutathione to protect active nitric oxide from oxidative breakdown. It also pairs effectively with Creatine Monohydrate for muscular energy production. Maintain a 2-hour separation window from whole-food protein shakes or high-protein meals to prevent intestinal carrier competition.

What to Expect Over Time:

  • Days 1–7: Initial cellular uptake begins. You may notice fuller muscle pumps during workouts and improved physical stamina without digestive heaviness.
  • Weeks 3–4: Consistent tissue saturation occurs. Circulating arginine levels stabilize, supporting faster waste clearance, reduced muscle soreness, and healthy peripheral warmth.
  • Months 2–3+: Long-term cardiovascular maintenance. Sustained endothelial nitric oxide synthesis promotes arterial flexibility, healthy vascular tone, and everyday circulatory vitality.

Physical Feel, Sensory Traits & Clean Ingredients

Pill Format & Ease of Use: Each two-piece vegetarian capsule (Size 00) measures approximately 7/8 inch in length. The smooth plant cellulose shell becomes slippery with water, gliding easily down your throat. If you prefer drinking your supplements, you can pull the capsule halves apart and stir the pure powder directly into water or juice.

Natural Aroma, Taste & Color: The vegetable capsule shell is completely flavorless and odorless, shielding your palate from any raw amino taste. Inside is a fine, clean white powder. Minor natural color variation between production lots is normal and reflects raw ingredient sourcing.

Other Ingredients Explained:

  • Hypromellose (cellulose capsule): A natural plant-derived capsule shell created from wood cellulose that dissolves swiftly in stomach acid without animal gelatin.
  • Stearic Acid (vegetable source): A natural plant fatty acid used in tiny amounts to lubricate packaging equipment and ensure clean capsule filling.
  • Silicon Dioxide: A natural food-grade mineral compound that absorbs ambient moisture and prevents fine powder from caking.

Proper Storage: Store in a cool, dry place after opening. Keep the bottle tightly closed to shield the capsules from room humidity and heat. This bottle is made from 100% PCR (post-consumer recycled) resin to minimize environmental plastic waste.

Manufacturer Quality & Lab Testing Standards

Many bargain supplement brands sold in big-box stores purchase low-cost powders from untracked overseas brokers. Those products frequently suffer from synthetic degradation, unlisted fillers, and heavy metal accumulation. NOW Foods operates one of the most advanced analytical testing infrastructures in the natural products industry, performing over 19,000 analytical tests each month.

  • Heavy Metal Screening (ICP-MS): Inductively Coupled Plasma Mass Spectrometry checks every incoming batch for lead, arsenic, cadmium, and mercury down to parts-per-billion, beating California Proposition 65 limits.
  • Active Potency Testing (HPLC): High-Performance Liquid Chromatography verifies that each capsule contains 100% pure, biologically active L-citrulline without unlisted fillers or synthetic diluents.
  • Molecular Fingerprinting (FTIR): Fourier Transform Infrared Spectroscopy screens incoming materials against pure spectral standards to catch counterfeit ingredients at the door.
  • Microbiological Safety: Automated cleanroom assays verify the total absence of harmful pathogens, including Salmonella, Escherichia coli, and Staphylococcus aureus.

NOW Foods manufacturing facilities maintain continuous Underwriters Laboratories (UL Solutions) cGMP registration and hold ISO/IEC 17025 accreditation for analytical laboratory excellence.

Complete Supplement Facts Panel

Supplement Facts

Serving Size: 2 Veg Capsules
Servings Per Container: 90
Description Amount per Serving % Daily Value
Calories 5
L-Citrulline 1.5 g (1,500 mg) †
† Daily Value not established. Note: Each individual vegetarian capsule contains 750 mg of pure L-Citrulline.

Other Ingredients: Hypromellose (cellulose capsule), Stearic Acid (vegetable source) and Silicon Dioxide.

Allergen Statement: Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Caution: For adults only. Consult physician if pregnant/nursing, taking medication (especially blood pressure medications and nitrates or other vasodilating drugs), or have a medical condition (especially abnormal blood pressure). Keep out of reach of children.

Additional Notes: Natural color variation may occur in this product. Made and quality tested in the USA with globally sourced ingredients. Store in a cool, dry place after opening. Family owned since 1968. This bottle is made from 100% PCR (post-consumer recycled) resin.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Scientific References & Clinical Studies

  1. Schwedhelm, E., Maas, R., Freese, R., Jung, D., Lukacs, Z., Jambrecina, A., Spickler, W., Schulze, F., & Böger, R. H. (2008). "Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism." British Journal of Clinical Pharmacology, 65(1), 51–59. PMID: 17662090.
  2. Curis, E., Nicolis, I., Moinard, C., Osowska, S., Zerrouk, N., Bénazeth, S., & Cynober, L. (2005). "Almost all about citrulline in mammals." Amino Acids, 29(3), 177–205. PMID: 16082501.
  3. Bailey, S. J., Blackwell, J. R., Lord, T., Vanhatalo, A., Winyard, P. G., & Jones, A. M. (2015). "l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans." Journal of Applied Physiology, 119(4), 385–395. PMID: 26023227.
  4. Allerton, T. D., Proctor, D. N., Liebman, J. M., Pelitire, S. M., Stoyer, H. E., & Bryan, N. S. (2018). "l-Citrulline Supplementation: Impact on Cardiometabolic Health." Nutrients, 10(7), 921. PMID: 30029482.

Frequently Asked Questions

Can I open these veg capsules and stir the powder into a drink?

Yes. You can easily separate the two halves of the vegetarian capsule and pour the pure L-Citrulline powder into water, fruit juice, or a smoothie. The unflavored powder dissolves smoothly without gritty residue or sour acidity.

Why is pure L-Citrulline preferred over Citrulline Malate?

L-Citrulline provides 100% active free-form amino acid by weight. Citrulline malate is chemically bonded with malic acid, giving you only 50% to 67% actual citrulline per gram. Pure L-Citrulline offers full potency without the stomach burn often triggered by acidic malate powders.

When is the optimal time to take NOW L-Citrulline 750 mg for workouts versus general circulation?

For exercise endurance and muscle pumps, take 2 to 4 capsules (1,500 to 3,000 mg) 45 to 60 minutes before training on an empty stomach. For everyday cardiovascular and circulation support, take 1 to 2 capsules once or twice daily between meals with water.

Is L-Citrulline safe to combine with blood pressure medications or nitrates?

You must consult your physician before combining this product with prescription cardiovascular drugs. Because L-Citrulline naturally relaxes blood vessels and promotes circulation, combining it with antihypertensives, nitrates, or erectile dysfunction medications may cause blood pressure to drop lower than intended.

What is VitaNet's return policy if this supplement does not work for me?

VitaNet®, LLC offers an unconditional 100% money-back guarantee on all products. If you are unsatisfied for any reason, VitaNet will refund your purchase and even cover the return shipping costs, even on opened bottles.

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