NOW: DHA 500mg 180 Softgels

DHA 500mg - 180 Softgels



by   NOW FOODS
*MSRP:
$63.99
Our Price:
$37.12
Buy: at $37.12
(3 for $ 37.11ea. = $ 111.33 ) 42% OFF MSRP
UPC: 733739016133
# N1613

NOW DHA-500 Molecularly Distilled Enteric Coated Fish Oil (180 Softgels)

NOW® DHA-500 is a high-potency, pure fish oil softgel that gives your body 500 mg of Docosahexaenoic Acid (DHA) and 250 mg of Eicosapentaenoic Acid (EPA) in each single capsule. This concentrated formula gives your brain, eyes, and heart the essential omega-3 building blocks they need every day to stay healthy, sharp, and strong. With a special acid-resistant enteric coating, each softgel moves smoothly past your stomach to dissolve in your intestines, giving you maximum absorption with zero fish burps and no upset stomach.

Quick Specs Snapshot

  • Active Form & Potency: 500 mg DHA and 250 mg EPA as purified ethyl esters per softgel (from 1,000 mg molecularly distilled fish oil concentrate).
  • Primary Cellular Target: Brain cell membranes, eye retinal cells, and cardiovascular blood vessel walls.
  • Supply & Value Math: 180 softgels deliver a full 6-month daily supply (1 softgel per day), giving you premium concentrated omega-3 nutrition for just pennies a day.
  • Formulation Purity: Molecularly distilled to eliminate heavy metals and toxins; non-GMO sunflower vitamin E; packaged in a 100% recycled bottle; free of gluten, soy, milk, wheat, and shellfish.

Smart Buyer's Guide & Fish Oil Form Comparison

Why the Form Matters: Many cheap grocery store fish oils are weak and diluted, often providing only 120 mg of DHA per giant pill. That means you have to swallow three or four large pills every day just to get a helpful dose. Standard softgels also break down right away inside your warm stomach acid, which creates sour, unpleasant fish burps. NOW DHA-500 provides over four times the DHA in a single softgel and uses a targeted enteric coating that protects the oil from stomach acid, letting it open gently in the small intestine for better digestive comfort [4].

Ideal For Shoppers Who:

  • ✓Want targeted nutritional support for clear memory, daily focus, and long-term brain health.
  • ✓Spend long hours on digital screens and want to support healthy eye moisture, tear production, and retinal function.
  • ✓Dislike the nausea, repeating odor, and fishy aftertaste caused by ordinary, uncoated fish oil pills.

Consider Another Option If:

  • ✗You follow a strict vegan or vegetarian diet and need an algae-based omega-3 source (this formula is made from wild ocean fish and bovine gelatin).
  • ✗You have a severe, medically diagnosed allergy to fish (anchovies, sardines, or tuna).
  • ✗You are looking specifically for a high-EPA formula (such as a 2:1 or 3:1 EPA-to-DHA ratio) for joint support, rather than a brain-focused DHA formula.

Every bottle purchased through VitaNet®, LLC is protected by our unconditional 100% money-back guarantee—we even pay the return shipping, even on opened bottles—so you can experience the digestive comfort and purity of this formula completely risk-free.

How DHA and EPA Work Inside Your Cells

Your body cannot make omega-3 fats on its own, so you must get them from your diet. DHA (Docosahexaenoic Acid, C22H32O2) is the most abundant omega-3 fat found in your brain and eyes [1]. Think of DHA as a fundamental structural building block. It makes up a large portion of the gray matter in your brain and the retina at the back of your eyes [1].

Every cell in your body is surrounded by a flexible skin called a cell membrane. DHA slips directly into these cell membranes, keeping them fluid, soft, and flexible [2]. In your brain, fluid membranes allow nerve cells to send electrical signals and chemical messages to one another quickly and smoothly. This helps support learning, quick thinking, and healthy memory retention as you age [1, 2]. In your eyes, DHA helps the light-sensing cells in your retina turn light into clear visual images that travel directly to your brain [1].

EPA (Eicosapentaenoic Acid, C20H30O2) works alongside DHA as a cellular protector. While DHA builds the cell structure, EPA helps your body create signaling molecules called resolvins and eicosanoids [2, 3]. These compounds help maintain smooth blood circulation, support blood vessel flexibility, and promote a calm, balanced response to everyday physical stress [3].

The enteric coating on this softgel acts like a protective raincoat. Your stomach contains strong digestive acid (pH 1.5 to 2.5). Uncoated fish oil dissolves in the stomach and floats to the top, which causes acid reflux and fishy burps. NOW's plant-based coating stays completely sealed in stomach acid. It only opens once it reaches your small intestine (pH 6.8 to 7.4), where digestive lipases and bile salts can easily absorb the healthy fats without any unpleasant odor [4].

Daily Dosing, Timing & Synergy Guide

Optimal Timing & Meal Pairing: Take 1 softgel daily with a meal that contains healthy dietary fats, such as eggs, avocado, olive oil, nuts, or yogurt. Dietary fats signal your body to release bile and lipase enzymes, which help break down and absorb the concentrated omega-3 ethyl esters much more effectively [4, 5].

Daily Timing Strategy: You can take your softgel in the morning with breakfast or in the evening with dinner. Because the enteric coating prevents stomach upset and reflux, taking it with your evening meal will not cause heartburn or disrupt your sleep. If you choose to take 2 softgels daily based on your doctor's advice, split them between two separate meals to keep a steady supply of fatty acids circulating in your bloodstream throughout the day.

Smart Synergies & Spacing Rules:

  • ✓Great Companions: DHA-500 pairs perfectly with fat-soluble vitamins like Vitamin D3 and Vitamin K2, as well as Coenzyme Q10 (CoQ10), which absorb together smoothly and support heart and brain health.
  • ✗Spacing Rule: Take this softgel at least 2 hours away from bulk fiber supplements (like psyllium husk) or fat-binding products (like chitosan), because fiber sponges can trap the oil and carry it out of your body before it can be absorbed.

Timeline of Results:

  • Week 1: Smooth, clean digestion right away. The enteric coating ensures zero fishy burps, aftertaste, or stomach heaviness.
  • Weeks 3–4: DHA and EPA concentrations begin to rise in your red blood cells and eye tissues, supporting natural tear film moisture and everyday mental clarity.
  • Months 2–3+: Deep structural saturation occurs in your brain cell membranes and blood vessels, promoting long-term cardiovascular health and healthy cognitive function.

Physical Softgel Details & Clean Ingredient Profile

Delivery Format & Swallowability: NOW DHA-500 comes in a golden, oblong softgel. Even though it holds a full 1,000 mg of concentrated fish oil, the enteric coating creates a smooth, semi-matte surface. When swallowed with a normal sip of water, it slides easily down the throat without sticking or catching.

Natural Aroma, Taste & Color: When you open the bottle, you will notice it is virtually odorless. There is no sharp fish smell. The softgels have a natural amber-golden color. Because NOW uses real wild-caught ocean fish, slight natural color differences can occur from batch to batch, which is normal for unbleached, natural marine oils.

Every Inactive Ingredient Explained:

  • Bovine Gelatin (BSE-free): Forms the sturdy outer capsule shell, sourced safely from certified disease-free cattle.
  • Glycerin: A gentle, plant-derived moisturizer that keeps the softgel flexible so it does not crack during storage.
  • Enteric Coating (pharmaceutical glaze, ethyl alcohol, ammonium hydroxide, glycerin, sunflower lecithin, medium chain triglycerides): A food-grade protective layer that shields the capsule from stomach acid so it opens only in the small intestine.
  • Water: Purified water used to form the gelatin capsule.
  • d-alpha Tocopherol (from sunflower): Natural Vitamin E derived from non-GMO sunflowers, added as a protective antioxidant to keep the delicate omega-3 oils fresh and prevent oxidation.
  • Fish Source: Wild-caught anchovies, sardines, and tuna harvested from clean ocean waters off the coasts of Peru, Morocco, China, and Mauritius.

Storage & Freshness: Store your bottle in a cool, dry place after opening. Make sure the cap is screwed on tightly. Keep it out of steamy bathrooms and away from hot kitchen stoves or direct sunlight to keep the oils fresh all the way to the 180th softgel.

Supplement Facts, Quality Standards & Lab Testing

Description Amount per Serving % Daily Value
Serving Size: 1 Softgel | Servings Per Container: 180
Calories 10 —
Total Fat 1 g 1%**
Fish Oil Concentrate 1 g (1,000 mg) †
Docosahexaenoic Acid (DHA) as ethyl esters 500 mg †
Eicosapentaenoic Acid (EPA) as ethyl esters 250 mg †

** Percent Daily Values are based on a 2,000 calorie diet. † Daily Value not established.

NOW Brand Lab Testing & Contaminant Controls

NOW operates one of the most advanced, privately owned supplement testing laboratories in North America, staffed by over 150 chemists, microbiologists, and laboratory analysts. Unlike unverified store brands that simply buy bulk oil and bottle it without testing, NOW verifies every incoming batch of raw fish oil and every finished lot in-house using cutting-edge instruments:

  • ✓Heavy Metal Testing via ICP-MS: Inductively Coupled Plasma Mass Spectrometry tests for toxic heavy metals like mercury, lead, cadmium, and arsenic down to parts-per-billion detection limits.
  • ✓Molecular Distillation: Low-temperature vacuum distillation strips away environmental contaminants such as PCBs, dioxins, and furans while preserving delicate omega-3 bonds.
  • ✓Strict GOED & Prop 65 Standards: NOW tests its oils to meet or exceed the strict standards set by the Global Organization for EPA and DHA Omega-3 (GOED) and California Proposition 65, ensuring peroxide and p-anisidine oxidation values remain far below industry limits so your oil is always fresh.

Curator's Note from VitaNet®, LLC: Family-owned and operating independently since 1995, VitaNet® brings over 31 years of direct supplement expertise to our customers. We only partner with manufacturers like NOW who own their testing facilities and adhere to certified current Good Manufacturing Practices (cGMP). Reviewed by the VitaNet® Nutritional Science Team.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Frequently Asked Questions & Scientific References

Why is this fish oil enteric coated, and does it really eliminate fish burps?

Yes. The enteric coating is made from safe, food-grade ingredients that do not dissolve in stomach acid. Standard fish oil capsules break open in your stomach, where the lighter oil floats on top of stomach fluids and produces fishy burps. The enteric coating keeps the softgel intact until it reaches the neutral pH of your small intestine, preventing reflux and repeating taste entirely [4].

Can I cut or puncture the softgel and squeeze the oil into a smoothie?

You can, but it is not recommended. Puncturing the softgel defeats the purpose of the enteric coating, which is specifically designed to keep the oil enclosed until it reaches your intestines. If you pierce the capsule, you will taste the natural fish oil and lose the protection against fish burps.

Will taking this DHA-500 softgel break my intermittent fast?

Each softgel contains 10 calories and 1 gram of fat. For strict water-only fasting, any calories technically break a fast. For metabolic flexibility or time-restricted eating, 10 calories of pure fat will not cause an insulin spike. However, because omega-3 fats absorb best when taken with a meal containing dietary fats, we recommend taking your softgel with your first meal when you break your fast [5].

What is the difference between DHA and EPA, and why does this formula emphasize DHA?

DHA and EPA are both essential omega-3 fatty acids, but they have different jobs. DHA is a major structural component of brain tissue and retinal cells in the eye [1]. EPA is primarily used by the body to produce balancing molecules that support cardiovascular circulation and vascular health [3]. This formula provides a 2:1 ratio of DHA to EPA (500 mg DHA to 250 mg EPA), making it ideal for individuals who want targeted support for memory, brain function, and visual clarity.

How does NOW ensure this fish oil is free of mercury and environmental pollutants?

NOW uses cold-water, wild-caught fish (anchovies, sardines, and tuna) that are molecularly distilled under vacuum conditions. This process separates pure fatty acids from heavy metals like mercury, lead, and cadmium, as well as PCBs and dioxins. Every finished production batch is verified in NOW's in-house laboratories using mass spectrometry to meet strict GOED and California Proposition 65 safety standards.


Scientific References:

  1. Salem, N., Jr., Litman, B., Kim, H. Y., & Gawrisch, K. (2001). Mechanisms of action of docosahexaenoic acid in the nervous system. Lipids, 36(9), 945–959.
  2. Calder, P. C. (2012). Mechanisms of action of (n-3) fatty acids. The Journal of Nutrition, 142(3), 592S–599S.
  3. Mozaffarian, D., & Wu, J. H. (2011). Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events. Journal of the American College of Cardiology, 58(20), 2047–2067.
  4. Schuchardt, J. P., & Hahn, A. (2013). Bioavailability of long-chain omega-3 fatty acids. Prostaglandins, Leukotrienes and Essential Fatty Acids, 89(1), 1–8.
  5. Lawson, L. D., & Hughes, B. G. (1988). Human absorption of fish oil fatty acids as triacylglycerols, free acids, or ethyl esters. Biochemical and Biophysical Research Communications, 152(1), 328–335.
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