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NOW Foods CoQ10 60 mg with Omega-3 Fish Oil — 120 Softgels
NOW Foods CoQ10 60 mg with Omega-3 Fish Oil combines two of the most researched cardiovascular and cellular energy nutrients into a single, high-absorption softgel. By pairing 60 mg of pure, pharmaceutical-grade Coenzyme Q10 (ubiquinone) with 250 mg of molecularly distilled omega-3 fish oil concentrate, this advanced formula bypasses the primary hurdle of traditional CoQ10 supplementation: poor fat solubility and intestinal absorption.
Coenzyme Q10 is a naturally occurring compound concentrated inside the mitochondria of hard-working tissues, especially your heart muscle, brain, and liver. However, your body's natural production of CoQ10 begins to decline after age 30 and drops further under physical stress or when taking certain cholesterol medications. Because crystalline CoQ10 requires dietary lipids to be broken down and absorbed through the lymphatic system, suspending it in pure fish oil, rice bran oil, and lecithin ensures optimal cellular uptake compared to dry powders or capsules.
- ✓Cardiovascular & Cellular Support: Fuels myocardial ATP energy production while delivering essential EPA and DHA fatty acids.
- ✓100% All-Trans Form: Contains only the bio-identical, yeast-fermented all-trans isomer of CoQ10 with zero synthetic cis-isomers.
- ✓Synergistic Lipid Base: Naturally solubilized in omega-3 fish oil, soy lecithin, and rice bran oil for enhanced bioavailability.
- ✓Certified Purity: Molecularly distilled to eliminate heavy metals (lead, mercury, cadmium, arsenic), PCBs, and dioxins.
- ✓Clean Formulation: Free of titanium dioxide, artificial colors, hydrogenated oils, gluten, and dairy.
Mechanism of Action: How CoQ10 & Omega-3 Work Synergistically
To appreciate why this dual-action formula excels, it helps to understand how both nutrients operate inside your cells:
1. Mitochondrial ATP Energy Generation
Your heart beats roughly 100,000 times every day without a single pause. To sustain this constant workload, cardiac muscle cells rely on cellular engines called mitochondria, which generate adenosine triphosphate (ATP). Coenzyme Q10 acts as an indispensable electron shuttle inside the inner mitochondrial membrane, transferring electrons between Complexes I, II, and III of the respiratory chain. Without adequate CoQ10, mitochondrial electron transport slows down, limiting cellular energy output and increasing fatigue.
2. Endothelial Integrity & Vascular Flexibility
The marine omega-3 fatty acids EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) integrate directly into the phospholipid bilayers of cardiac and vascular cell membranes. This fluid membrane structure supports arterial elasticity, encourages healthy nitric oxide signaling for normal blood vessel dilation, and supports balanced cytokine pathways across the cardiovascular system.
3. Overcoming the CoQ10 Absorption Hurdle
Standard CoQ10 raw material is a crystalline, hydrophobic (water-insoluble) powder with a high melting point (~48°C). When taken as an unformulated dry tablet or capsule, over 90% is eliminated without reaching the bloodstream. By dissolving fermented all-trans CoQ10 within fish oil lipids, rice bran oil, and 200 mg of soy lecithin, this formula promotes the formation of tiny lipid droplets (micelles) in the small intestine. These micelles are efficiently absorbed through the intestinal lining and transported via the lymphatic system directly into systemic circulation.
Authoritative Scientific Evidence
- Mitochondrial Support & Cardiac Function: In the landmark multi-center, randomized, double-blind Q-SYMBIO trial published in JACC: Heart Failure (Mortensen SA, et al., 2014; 2(6):641–649), long-term adjunctive CoQ10 supplementation significantly reduced major adverse cardiovascular complications and preserved functional stamina in patients needing cellular energy support.
- Long-Term Biomarker & Vascular Defense: The prospective KiSel-10 clinical trial published in the International Journal of Cardiology (Alehagen U, et al., 2013; 167(5):1860–1866) showed that daily ubiquinone intervention substantially improved cardiovascular health markers, lowered NT-proBNP levels, and maintained physical vitality in aging adults over a multi-year evaluation period.
- Bioavailability Kinetics: Research indexed in Molecules (Schulz C, et al., 2019; 24(14):2585) demonstrated that lipid-dissolved CoQ10 formulations utilizing oil and lecithin carriers achieve significantly higher peak plasma concentrations (Cmax) and area-under-the-curve (AUC) bioavailability than dry powder preparations.
Supplement Facts & Complete Ingredient Profile
Every single softgel delivers verified potency and standardized levels of active ubiquinone and omega-3 marine triglycerides:
| Serving Size: 1 Softgel | Servings Per Container: 120 |
|---|---|
| Active Ingredient | Amount Per Serving (% DV) |
| Calories | 5 |
| Total Fat | 0.5 g (< 1%*) |
| Coenzyme Q10 (CoQ10) (Ubiquinone, all-trans form) | 60 mg (†) |
| Natural Fish Oil Concentrate | 250 mg (†) |
| — Eicosapentaenoic Acid (EPA) | 40 mg (†) |
| — Docosahexaenoic Acid (DHA) | 25 mg (†) |
| Soy Lecithin | 200 mg (†) |
* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value not established.
Complete Ingredients:
Active Components: Coenzyme Q10 (Ubiquinone), Fish Oil Concentrate (Anchovies, Sardines, Mackerel), Soy Lecithin.
Softgel Capsule Components: Bovine gelatin (BSE-free), glycerin, water, carob, annatto extract.
Carrier & Antioxidant Blend: Rice bran oil, yellow beeswax, d-alpha tocopherol, and mixed tocopherols.
Allergen & Manufacturing Specifications:
Contains: Fish (anchovies, sardines, mackerel) and Soy.
Manufactured Without: Wheat, gluten, milk, egg, shellfish, or sesame ingredients. Produced in an A-rated Good Manufacturing Practices (GMP) compliant facility that processes other ingredients containing these allergens.
Packaging: Packaged in an amber, BPA-free bottle manufactured from 100% post-consumer recycled (PCR) resin.
NOW® World-Class Lab Purity & Contaminant Constraints
Marine oils and botanical extracts can carry risks of chemical degradation, rancidity, and environmental pollutants if not rigorously controlled. NOW Foods operates one of the most advanced, privately held analytical testing facilities in North America, with in-house laboratories accredited to ISO/IEC 17025 standards. Every incoming production batch of CoQ10 and fish oil must pass comprehensive chemical and microbiological clearance before release.
1. Heavy Metal Screening via ICP-MS
Using Inductively Coupled Plasma Mass Spectrometry (ICP-MS), samples are ionized at temperatures up to 10,000°C to detect toxic trace metals at the parts-per-billion (ppb) level. NOW enforces strict safety thresholds that meet or exceed federal and global pharmacopeial standards:
- Lead (Pb): Less than 0.05 mg/kg
- Cadmium (Cd): Less than 0.1 mg/kg
- Mercury (Hg): Less than 0.1 mg/kg
- Inorganic Arsenic (As): Less than 0.1 mg/kg
2. Molecular Distillation & GOED Monograph Limits
The fish oil concentrate in this formula is purified via low-heat molecular distillation under a high vacuum to remove volatile pollutants while safeguarding fragile omega-3 bonds. NOW tests every lot via Gas Chromatography-Tandem Mass Spectrometry (GC-MS/MS) to confirm full compliance with the strict standards set by the Global Organization for EPA and DHA Omega-3s (GOED):
- Polychlorinated Biphenyls (PCBs): Maximum 0.09 mg/kg (exceeding strict California Prop 65 safety rules)
- Dioxins & Furans (PCDDs & PCDFs): Maximum 1.75 pg WHO-TEQ/g
- Total Dioxin-Like PCBs: Maximum 3.0 pg WHO-TEQ/g