Full Spectrum™ Turkey Tail Mushroom for Cellular Defense & Immune Modulation
FS Coriolus 1000mg Extract by Planetary Herbals delivers one of the world’s most thoroughly researched botanical immunomodulators in a highly concentrated, bioavailable tablet. Known scientifically as Trametes versicolor (and historically categorized as Coriolus versicolor, Yun Zhi in Traditional Chinese Medicine, or Kawaratake in Japan), Turkey Tail mushroom has been revered for centuries for its profound ability to reinforce vital energy, protect hepatic function, and fortify immune resilience.
Formulated under the clinical direction of professional acupuncturist and herbalist Michael Tierra, L.Ac., O.M.D., each 2-tablet serving provides a robust 2,000 mg (2 g) of pure Coriolus versicolor fruiting body extract, yielding an industry-leading 1,000 mg of extract per tablet. Planetary Herbals utilizes an advanced hot-water extraction process to yield a guaranteed 50% bioactive polysaccharides, delivering the high molecular weight beta-glucans necessary to stimulate both innate and adaptive cellular defenses.
Biochemical Profile & Mechanisms of Action: How Coriolus Protects Cellular Health
Unlike raw, non-extracted mushroom powders that pass through the digestive tract largely unabsorbed due to indigestible fungal chitin walls, FS Coriolus 1000mg Extract concentrates the exact water-soluble bioactive proteoglycans identified in modern mycological pharmacology: Polysaccharide-K (PSK / Krestin) and Polysaccharide-Peptide (PSP).
The high-potency beta-1,3 and beta-1,6-glucan branched chains in Coriolus bind directly to specific pattern recognition receptors (PRRs)—specifically Dectin-1, Complement Receptor 3 (CR3), and Toll-like Receptors (TLR-2 and TLR-4)—located on human macrophages, dendritic cells, and monocytes. This receptor binding triggers an intracellular signaling cascade that stimulates:
Natural Killer (NK) Cell Cytotoxicity: Enhances the surveillance and targeted destruction of compromised, damaged, or atypical cells.
Cytokine Production: Promotes balanced gene expression of critical regulatory cytokines, including Interleukin-2 (IL-2), Interleukin-12 (IL-12), and Interferon-gamma (IFN-?).
Emerging gastrointestinal research confirms that Coriolus polysaccharides act as targeted, non-digestible prebiotic fibers within the colon. Clinical human trials demonstrate that oral intake of Coriolus versicolor PSP selectively enriches beneficial gut commensals—specifically expanding populations of Bifidobacterium spp. and Lactobacillus spp.—while suppressing pro-inflammatory clostridial clusters. In turn, these beneficial bacteria ferment beta-glucans into immunomodulating Short-Chain Fatty Acids (SCFAs) such as butyrate, which nourish colonocytes and reinforce systemic gut-barrier integrity.
3. Broad-Spectrum Antioxidant & Hepatoprotective Support
Planetary Herbals FS Coriolus extract contains a concentrated spectrum of phenolic acids and flavonoid antioxidants (including quercetin and baicalein derivatives). These bioactives neutralize reactive oxygen species (ROS), attenuate lipid peroxidation in cell membranes, and promote the endogenous transcription of primary antioxidant enzymes like Superoxide Dismutase (SOD) and Glutathione Peroxidase (GSH-Px).
The Full Spectrum™ Advantage: 100% Fruiting Body vs. Mycelium on Grain
Not all mushroom supplements are created equal. Many commercial turkey tail products consist primarily of mycelial biomass grown on cereal grains (such as oats, barley, or rice), resulting in a finished product that is 60–70% starch and unfermented grain filler with minimal active beta-glucans.
Pure Fruiting Body Source: Planetary Herbals derives this formula strictly from mature mushroom fruiting bodies, ensuring the natural concentrations of secondary metabolites and triterpenes developed during the mushroom's full life cycle.
Multi-Stage Hot-Water Extraction: Active beta-glucans are naturally bound inside tough chitin cell walls that human stomach acid cannot digest. Planetary Herbals utilizes a validated hot-water extraction method to dissolve and concentrate these polysaccharides into a bioavailable 50% standardized extract.
Third-Party Laboratory Verified: Every batch is rigorously assayed for purity, heavy metal compliance, solvent-free processing, and microbiological safety under strict current Good Manufacturing Practices (cGMP).
Complete Supplement Facts & Ingredients
Compare our clinically standardized potency against standard mushroom powders:
Supplement Facts
Serving Size: 2 Tablets
Servings Per Container: 30
Amount Per Serving
% Daily Value*
Calories
10
Total Carbohydrate
3 g (1%*)
Dietary Fiber
1 g (4%*)
Iron (naturally occurring)
2 mg (11%)
Sodium
10 mg (<1%)
Coriolus versicolor Fruiting Body Extract (Standardized to 50% Polysaccharides [1,000 mg])
2 g (2,000 mg) †
* Percent Daily Values (%DV) are based on a 2,000 calorie diet.
† Daily Value not established.
Contains no yeast, dairy, egg, gluten, soy, or wheat.
Contains no sugar, starch, salt, preservatives, or artificial colors, flavors, or fragrances.
Manufactured in an FDA-audited, cGMP-compliant facility.
Clinical Administration & Suggested Use
Standard Maintenance Protocol: Take 2 tablets daily with water, preferably between meals or as directed by your healthcare professional. Splitting the dose (1 tablet in the morning and 1 tablet in the late afternoon) supports consistent circulating polysaccharide availability.
Intensive Support Protocol: In traditional and clinical applications requiring concentrated cellular defense, qualified practitioners often recommend taking 2 tablets two to three times daily for a defined therapeutic window. Always consult your qualified physician before exceeding label recommendations.
Safety, Contraindications & Drug Interactions
Clinical Precautions:
Immunosuppressive Medications: Because Coriolus versicolor stimulates immune activity (macrophages, NK cells, and T-cell signaling), individuals taking immunosuppressants (e.g., following organ transplantation or for active autoimmune conditions like systemic lupus erythematosus, rheumatoid arthritis, or multiple sclerosis) should avoid use unless authorized by their attending physician.
Surgery: Due to potential mild immunomodulatory and platelet interactions, discontinue use at least 2 weeks prior to elective surgical procedures.
Pregnancy & Lactation: If you are pregnant, planning to become pregnant, or breastfeeding, do not use without direct guidance from your healthcare provider.
Pediatric Use: Keep out of reach of children. Store in a cool, dry place with the tamper-evident seal intact.
Peer-Reviewed Scientific References
Pallav, K., et al. (2014). Effects of polysaccharopeptide from Trametes versicolor and amoxicillin on the gut microbiome of healthy volunteers: a randomized clinical trial. Gut Microbes, 5(4), 458–467.
Standish, L. J., et al. (2008). Trametes versicolor mushroom immune therapy in breast cancer. Journal of the Society for Integrative Oncology, 6(3), 122–128.
Fisher, M., & Yang, L. X. (2002). Anticancer effects and mechanisms of polysaccharide-K (PSK): implications of cancer immunotherapy. Anticancer Research, 22(3), 1737–1754.
Kee, C. W., et al. (2017). The structural features of mushroom polysaccharides and their biological functions in human immune responses: A review. International Journal of Biological Macromolecules, 104, 1210–1222.
Saleh, M. H., et al. (2017). Immunomodulatory properties of Coriolus versicolor: The role of beta-glucans and fungal proteoglycans in natural killer cell cytolytic activation. Frontiers in Immunology, 8, 1087.
Frequently Asked Questions About Planetary Herbals FS Coriolus 1000mg Extract
What is the difference between Coriolus versicolor and Turkey Tail?
They are the exact same mushroom. Coriolus versicolor (also classified scientifically as Trametes versicolor) is the botanical taxonomic name, while "Turkey Tail" is the common English name given because its concentric bands of color resemble the fanned tail feathers of a wild turkey. In Asian pharmacopeias, it is also known as Yun Zhi (China) and Kawaratake (Japan).
Why is a 50% polysaccharide standardization important?
Standardization guarantees potency and therapeutic consistency. Many raw mushroom powders contain variable polysaccharide levels—often under 10%—with the majority being inactive starch or cellulose. A 50% polysaccharide standardization ensures that every 2-tablet serving supplies at least 1,000 mg of pure, bioactive immune-modulating beta-glucans and proteoglycans.
How does Coriolus extract support Natural Killer (NK) cell activity?
The complex beta-D-glucans found in Coriolus bind to Dectin-1 and Toll-like receptors on immune sentinel cells like macrophages and dendritic cells. This interaction triggers the release of signaling cytokines (such as IL-2 and IFN-?) that prime and activate Natural Killer (NK) cells, enhancing their ability to identify and neutralize atypical or stressed cells throughout the body.
Is this product made from mushroom fruiting bodies or mycelium on grain?
Planetary Herbals FS Coriolus 1000mg Extract is extracted directly from 100% genuine mushroom fruiting bodies, not mycelial grain biomass. Fruiting body extracts provide higher concentrations of bioactive beta-glucans without the diluted residual starches and grain fillers common in lab-grown mycelium.
What is the best time of day to take Planetary Herbals Coriolus tablets?
For maximum absorption, take 1 tablet in the morning and 1 tablet in the afternoon or evening on an empty stomach with a full glass of water. If you have a sensitive digestive tract, taking the tablets alongside a light meal is equally effective.
Can I take Coriolus extract alongside prescription medications?
While Coriolus has an excellent safety record, it actively stimulates immune pathways. As a result, it should not be taken with prescription immunosuppressive medications (such as cyclosporine, tacrolimus, or prednisone) without direct medical oversight. Always discuss dietary supplement additions with your physician or pharmacist.
