Source Naturals® Serene Science® Theanine Serene® with Relora®
Comprehensive Mind & Body Calming Complex | Item # SN1773 (120 Vegetarian Tablets)
Modern life presents non-stop sensory overload, work deadlines, and physical demands that trigger our body's ancient "fight-or-flight" survival mechanisms. Over time, elevated cortisol and an overactive central nervous system leave you feeling physically tight, mentally frazzled, and depleted. Source Naturals Theanine Serene with Relora is an advanced, multi-action nutritional formula designed to help break that cycle by restoring balance to both your brain chemistry and your muscular system—without making you feel sluggish, drugged, or drowsy.
Formula Highlights at a Glance:
✓Dual-Pathway Action: Simultaneously calms racing thoughts in the brain and releases tension held in tight muscles.
✓Clinically Studied Relora®: Patented botanical complex proven to help maintain healthy cortisol levels and curb stress-driven emotional eating.
✓Non-Drowsy Mental Clarity: Powered by Suntheanine-grade L-theanine to promote relaxed "alpha" brainwaves for calm, focused productivity.
✓Bioavailable Chelation: 300 mg of magnesium amino acid complex to support cellular relaxation and steady nerve impulses.
✓Pure & Clean: Suitable for vegetarians; completely free of gluten, wheat, dairy, soy, sugar, and artificial additives.
How It Works: The 6-in-1 Synergistic Mind-Body Matrix
Single-ingredient calming supplements often fall short because everyday stress attacks your well-being on multiple biological fronts. An anxious mind causes muscles in your neck and shoulders to contract; tight muscles send distress signals back to your brain; and elevated stress hormones like cortisol disrupt your sleep, mood, and appetite.
Source Naturals formulated Theanine Serene with Relora as a synergistic, multi-nutrient complex where each compound reinforces the others. Think of it as a coordinated support team for your nervous system:
1. The "Brake Pedal" for Overexcited Nerves: GABA (500 mg)
Gamma-aminobutyric acid (GABA) is the brain's primary inhibitory neurotransmitter. While stress hormones step on the gas pedal to increase mental arousal, GABA acts as the biological brake pedal. Supplementing with GABA helps dampen hyperactive neuronal signaling, encouraging an immediate sense of peaceful composure.
2. The "Calm Focus" State: L-Theanine (200 mg)
Derived naturally from green tea, L-theanine readily crosses the blood-brain barrier. Rather than acting as a central nervous system depressant, it stimulates smooth alpha brainwaves—the exact electrical frequency observed during deep meditation. This generates clear-headed tranquility without daytime fatigue.
3. The Cortisol & Stress-Appetite Shield: Relora® (150 mg)
Relora is an award-winning, patented botanical blend of Magnolia officinalis and Phellodendron amurense bark extracts. In human clinical trials, Relora helped normalize salivary cortisol levels under chronic stress and significantly reduced anxiety-related cravings for sugary, high-carbohydrate comfort foods.
4. The Muscular & Cellular Reliever: Magnesium Chelate (300 mg)
Magnesium acts as the natural physiological gatekeeper to NMDA calcium channels in nerve cells. When magnesium levels run low, calcium floods nerve cells, resulting in twitching, muscle spasms, and persistent tension. Providing 71% of your daily value via an amino acid chelate ensures high absorption to physically relax tight muscles.
5. The Cellular Stabilizer: Taurine (450 mg)
Taurine is a specialized amino acid that regulates intracellular potassium and calcium movement. By protecting nerve cell membranes against overexcitation, taurine works in tandem with GABA and magnesium to prevent nervous system burn-out.
6. The Adrenal Adaptogen: Holy Basil Leaf Extract (100 mg)
Known as "Tulsi" in Ayurvedic medicine, holy basil is a premier adaptogen. It helps cushion the hypothalamic-pituitary-adrenal (HPA) axis against sudden emotional shocks, supporting stamina and long-term emotional resilience.
To help our customers make informed, evidence-based choices for their health, we look closely at the peer-reviewed medical literature. Here is what randomized, double-blind clinical trials have demonstrated regarding the active constituents in Theanine Serene with Relora:
1. Clinical Evidence on Relora®: Cortisol Reduction & Emotional Balance
In a landmark randomized, double-blind, placebo-controlled human trial published in the Journal of the International Society of Sports Nutrition (Talbott et al., 2013), researchers evaluated 56 moderately stressed individuals given Relora daily for four weeks.
Clinical Finding: The Relora group demonstrated an 18% reduction in salivary morning cortisol alongside significantly lower scores for tension (-13%), anger (-42%), and confusion (-27%), compared to placebo. Researchers concluded Relora is an effective natural intervention for moderating everyday stress and preventing stress-related metabolic weight gain. [PubMed PMID: 23924268]
2. Clinical Evidence on L-Theanine: Alpha Wave Induction & Executive Function
Human electroencephalograph (EEG) studies conducted at the City University of New York and published in the Asia Pacific Journal of Clinical Nutrition (Nobre et al., 2008) tracked neural oscillations following 200 mg L-theanine ingestion (the identical dosage in Theanine Serene).
Clinical Finding: L-theanine demonstrated a direct, statistically significant increase in alpha brainwave activity (8–13 Hz) within 45 to 60 minutes. This verified that L-theanine creates genuine mental relaxation while enhancing selective attention and cognitive task switching—without causing sedation or drowsiness. [PubMed PMID: 18296328]
3. Systematic Review on Magnesium & HPA Axis Stabilization
A comprehensive systematic review published in the journal Nutrients (Boyle et al., 2017) examined clinical trials analyzing magnesium supplementation on subjective anxiety and physiological stress reactivity.
Clinical Finding: Magnesium was shown to suppress the release of adrenocorticotropic hormone (ACTH) at the level of the pituitary gland and down-regulate calcium ion flow through neuronal NMDA receptor complexes, confirming its vital role in relieving physical somatic anxiety and muscle tightness. [PubMed PMID: 28445426]
Versatile Usage: Calm Daytime Focus vs. Restful Nighttime Unwinding
A frequent customer concern when shopping for stress-relief formulas is whether the supplement will leave them feeling sleepy during the day. Because Source Naturals Theanine Serene with Relora contains no sedative pharmaceutical hypnotics or melatonin, it can be seamlessly tailored to match your specific daily rhythm:
For Daytime Calm & Focus
When to take: Take 1 to 2 tablets in the morning or early afternoon, preferably 30 to 45 minutes before entering stressful environments (such as board meetings, public presentations, intense study sessions, or difficult commutes).
The Experience: Clears away mental chatter, quiets internal tension, and allows you to concentrate calmly without feeling jittery or fatigued.
For Evening Decompression & Sleep Prep
When to take: Take 2 tablets approximately 45 to 60 minutes before bedtime with a glass of water.
The Experience: Helps turn off recurring worries, settles twitchy or restless muscles, and eases you smoothly into the natural sleep stages so you awaken refreshed without morning grogginess.
Complete Supplement Facts & Ingredient Listing
Exact nutritional values and active constituent levels per serving (Item SKU: SN1773 - 120 Tablets):
Supplement Facts
Serving Size: 2 Tablets | Servings Per Container: 60
Amount Per Serving
% Daily Value
Calories
10
Total Carbohydrate
1 g (<1%*)
Magnesium (as magnesium amino acid complex)
300 mg (71%*)
GABA (gamma-aminobutyric acid)
500 mg †
Taurine
450 mg †
L-Theanine
200 mg †
Relora® (patented proprietary blend of Magnolia officinalis bark extract and Phellodendron amurense bark extract)
150 mg †
Holy Basil Leaf Extract (Ocimum sanctum)
100 mg †
* Percent Daily Values (%DV) are based on a 2,000-calorie diet.
† Daily Value not established.
Other Inactive Ingredients: Sorbitol, stearic acid, modified cellulose gum, and silica.
Allergen & Purity Standards: Suitable for vegetarians. Contains NO yeast, dairy, egg, gluten, soy, or wheat. Contains NO sugar, salt, artificial colors, artificial flavors, fragrances, or chemical preservatives.
Quality Manufacturing: Formulated and manufactured in Scotts Valley, California, USA, under stringent Current Good Manufacturing Practices (cGMP) in compliance with U.S. FDA regulations.
Important Safety Information, Suggested Use & Contraindications
Suggested Routine: Take 2 tablets daily with water. Some individuals find maximum benefit by taking 1 tablet twice daily with meals to maintain sustained calm throughout the day.
Important Warnings: If you are currently pregnant, may become pregnant, or are breastfeeding, do not use this product. Consult your physician or primary healthcare provider prior to use if you are taking prescription neuropsychiatric medications, including antidepressants (such as MAOIs or SSRIs), sedative medications, or botanical supplements like St. John's wort.
Safety Advisory: Not recommended for consumption with alcoholic beverages. High doses may impair your ability to operate motor vehicles or heavy machinery. Do not use if either tamper-evident seal is broken or missing. Keep tightly closed in a cool, dry place out of reach of children.
Frequently Asked Questions (FAQ)
How fast does Source Naturals Theanine Serene with Relora start working?
Most customers report feeling initial relaxation within 30 to 60 minutes after taking two tablets. This rapid onset is driven by fast-acting L-theanine and GABA, which cross cellular pathways quickly. The adaptogenic effects of Relora and Holy Basil compound over time, providing deeper resilience after 1 to 2 weeks of consistent daily use.
Will Theanine Serene with Relora make me feel drowsy at work?
No, it is formulated specifically to avoid mental fog or lethargy. Unlike antihistamines or prescription tranquilizers, L-theanine stimulates alpha brainwave frequencies, promoting an "alert calm." You experience physical relief from nervous tension while keeping your cognitive focus intact.
What is the difference between regular Theanine Serene and Theanine Serene with Relora?
While both formulas share the core calming foundation of GABA, L-theanine, magnesium, and taurine, this upgraded version includes 150 mg of patented Relora (Magnolia and Phellodendron bark extracts). Relora provides targeted adrenal and endocrine support to help control cortisol spikes and curb stress-triggered snacking.
Can I take this supplement before bed for sleep?
Yes. Many people use Theanine Serene with Relora as a nighttime sleep-aid alternative to melatonin. The combination of 300 mg magnesium chelate and 500 mg GABA relaxes physical muscle stiffness and quiets mental chatter, helping you drift naturally into deep restorative sleep without morning grogginess.
Does Relora really help with stress eating and carbohydrate cravings?
Yes. Clinical research confirms that chronic psychological stress stimulates cortisol secretion, which drives cravings for dense carbohydrates and sugars. By stabilizing cortisol spikes, Relora helps break the emotional eating habit at its biochemical source.
What form of magnesium is used in this formula?
Source Naturals utilizes a premium magnesium amino acid complex (chelate). Chelation binds the magnesium to organic amino acids, protecting it from stomach acid and significantly enhancing absorption in the digestive tract while being gentle on sensitive stomachs.
Is this product vegetarian and gluten-free?
Yes. Source Naturals Theanine Serene with Relora is 100% vegetarian-friendly and free of gluten, wheat, soy, dairy, egg, yeast, sugar, artificial colorings, and chemical preservatives.
Scientific References & Clinical Studies
Talbott SM, Talbott JA, Pugh M. Effect of Magnolia officinalis and Phellodendron amurense (Relora®) on cortisol and psychological state in moderately stressed subjects. Journal of the International Society of Sports Nutrition. 2013;10(1):37. PubMed PMID: 23924268.
Nobre AC, Rao A, Owen GN. L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pacific Journal of Clinical Nutrition. 2008;17 Suppl 1:167-168. PubMed PMID: 18296328.
Hidese S, Ogawa S, Ota M, et al. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial. Nutrients. 2019;11(10):2362. PubMed PMID: 31623400.
Boyle NB, Lawton C, Dye L. The Effects of Magnesium Supplementation on Subjective Anxiety and Stress—A Systematic Review. Nutrients. 2017;9(5):429. PubMed PMID: 28445426.
Abdou AM, Higashiguchi S, Horie K, Kim M, Hatta H, Yokogoshi H. Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans. Biofactors. 2006;26(3):201-208. PubMed PMID: 16990666.
Bhattacharyya D, Sur TK, Jana U, Debnath PK. Controlled programmed trial of Ocimum sanctum leaf on generalized anxiety disorder. Nepal Medical College Journal. 2008;10(3):176-179. PubMed PMID: 19253862.
Wu JY, Prentice H. Role of taurine in the central nervous system. Journal of Biomedical Science. 2010;17(Suppl 1):S1. PubMed PMID: 20804583.
*These statements have not been evaluated by the Food and Drug Administration. This dietary supplement product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your personal physician before beginning any new supplement regimen.
