BosMed 500 - 60 sg

by Europharma / Terry Naturally

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UPC: 367703343064: # ep-34306

Why Standard Boswellia Fails: The AKBA vs. Beta-Boswellic Acid Ratio

Most commercial Boswellia serrata supplements sold by big-box retailers are crude, unpurified gum resins containing as little as 1% to 3% AKBA (Acetyl-11-keto-beta-boswellic acid).

AKBA is the single most pharmacologically active component of boswellia. It binds directly to 5-lipoxygenase (5-LOX), the primary enzyme responsible for converting arachidonic acid into pro-inflammatory leukotrienes (LTB4, LTC4, LTD4, and LTE4). These leukotrienes trigger tissue destruction, mucosal barrier breakdown in the gut, and smooth-muscle constriction in bronchial passages.

Arachidonic Acid
       ¦
   [5-LOX Enzyme]  ?-- BLOCKED BY PURE AKBA
       ?
  Leukotrienes
(LTB4, LTC4, LTD4, LTE4)
       ¦
   Inflammatory Cascade
 (Mucosal degradation & Bronchospasm)

Unstandardized extracts contain high concentrations of beta-boswellic acid (BBA) - often making up 50% to 85% of standard boswellia gum resin. Peer-reviewed pharmacological research reveals that beta-boswellic acid acts as a counter-agent to AKBA:

Competitive Receptor Interference: Beta-boswellic acid competes with AKBA for binding sites on the 5-LOX enzyme, functionally blunting AKBA’s inhibitory capacity.
Pro-Inflammatory Activity: Studies show unpurified beta-boswellic acids can actually promote the production of inflammatory mediators, negating the therapeutic benefits of the plant.
Poor Bioavailability: Crude boswellic acids have notoriously low intestinal absorption unless isolated, concentrated, and suspended in a lipid-soluble medium.

Terry Naturally’s BosMed line uses a specialized, solvent-free extraction process that concentrates AKBA to a minimum of 10% (up to 20% in specific extracts) while systematically filtering out unwanted beta-boswellic acids to less than 5% (virtually 0% in targeted batches).

Direct Specification Comparison

Feature	Standard Retail Boswellia	Terry Naturally BosMed Intestinal	Terry Naturally BosMed Respiratory
Extract Standardization	65% generic organic acids	Clinically standardized BosPure® / targeted AKBA	Clinically standardized BosPure® / targeted AKBA
Active AKBA Concentration	1% - 3%	= 10% pure AKBA	= 10% pure AKBA
Beta-Boswellic Acid Content	50% - 85% (competitive/pro-inflammatory)	Screened Out (Near 0%)	Screened Out (Near 0%)
Primary Enzyme Target	Weak, non-specific inhibition	Direct 5-LOX & TNF-alpha inhibition	Direct 5-LOX & Bronchial Leukotriene inhibition
Synergistic Co-Factors	None (pure single herb)	Coriander seed oil, Fennel oil, Caraway oil	Thyme oil, Ravintsara oil, Myrtle oil
Primary Indication	General joint stiffness	Intestinal lining integrity, lower GI comfort	Bronchial dilation, sinus drainage, lung clearway
Bioavailability Profile	Low (passes through unabsorbed)	High (lipophilic enteric delivery)	High (volatile aromatic essential oil matrix)

BosMed Intestinal: Targeted Mucosal Restoration

Chronic digestive discomfort rarely stems from a single pathway. While general inflammation involves COX-2 enzymes, the intestinal mucosal lining is particularly vulnerable to the 5-LOX leukotriene cascade. Elevated intestinal leukotrienes degrade the protective epithelial mucus layer, loosen tight junctions (zonula occludens), and lead to hyper-permeability.

The Synergistic Mechanism

BosMed Intestinal does not simply provide high-AKBA boswellia; it pairs the extract with concentrated botanical volatile oils designed to calm smooth-muscle spasms and restore the gut barrier.

High-AKBA Boswellia Extract: Blocks leukotriene synthesis at the lamina propria, reducing inflammatory signaling in the colon and small intestine without inhibiting beneficial COX-1 prostaglandins that safeguard the stomach lining.
Coriander Seed Oil (Coriandrum sativum): Clinically demonstrated to support healthy lower gastrointestinal motility, alleviate bloating, and ease smooth-muscle spasms through cholinergic pathway modulation.
Fennel Seed Oil (Foeniculum vulgare): Rich in anethole, fennel reduces gas formation, relaxes intestinal smooth muscle, and prevents cramping caused by localized irritation.
Caraway Seed Oil (Carum carvi): Acts as a dual antimicrobial and carminative, balancing gut microbiota while desensitizing visceral pain receptors in the enteric nervous system.

Recommended Usage Protocol

Take 1 softgel twice daily with food. For intensive mucosal repair, dosage can be increased to 1 softgel three times daily under functional practitioner guidance.

BosMed Respiratory: Targeted Upper and Lower Airway Support

The respiratory tract is extraordinarily sensitive to leukotriene production. When mast cells and eosinophils in lung tissue degranulate, they release cysteinyl leukotrienes (LTC4, LTD4, LTE4) - molecules up to 1,000 times more potent than histamine at triggering bronchoconstriction, excessive mucus secretion, and airway edema. Standard antihistamines do not touch the 5-LOX pathway. BosMed Respiratory bypasses surface-level histamine suppression to halt the production of respiratory leukotrienes at their source.

The Synergistic Mechanism

Purified High-AKBA Boswellia: Directly inhibits 5-LOX in bronchial epithelial tissues, preserving airway caliber and stopping the biochemical trigger of lung hyper-reactivity.
Thyme Oil (Thymus vulgaris standardized to thymol): A potent antispasmodic for bronchial smooth muscle that stimulates mucociliary clearance, helping the lungs expel trapped particulate matter.
Ravintsara Oil (Cinnamomum camphora chemotype cineole): Rich in 1,8-cineole (eucalyptol), ravintsara opens sinus and bronchial passages, supports immune defense in mucosal membranes, and thins thick bronchial secretions.
Myrtle Leaf Oil (Myrtus communis): Provides targeted antioxidant protection to fragile pulmonary alveoli and promotes easy sinus drainage.

Recommended Usage Protocol

Take 1 softgel daily for routine bronchial maintenance. During acute seasonal challenges or environmental exposure, take 1 softgel two to three times daily.

Clinical Differentiation: Why BosMed Outperforms Curcumin Alone

Many consumers use curcumin for systemic inflammation, but curcumin primarily acts on NF-kB and COX-2 pathways. It demonstrates relatively weak direct inhibition of 5-LOX. BosMed's isolated AKBA targets the 5-LOX pathway, which curcumin misses. When managing mucosal or epithelial inflammation—such as in the gut or lungs—inhibiting 5-LOX is far more critical than inhibiting COX pathways. Furthermore, standard NSAIDs block COX-1 and COX-2, inadvertently shunting arachidonic acid directly into the 5-LOX pathway and worsening gut ulceration or bronchial constriction. BosMed achieves targeted anti-inflammatory signaling without disturbing COX homeostasis.

Frequently Asked Questions

What makes Terry Naturally BosMed different from standard frankincense/boswellia?

Standard boswellia resin contains 50% to 85% beta-boswellic acid, an inert or pro-inflammatory compound that interferes with therapeutic absorption. BosMed isolates the active healing compound - AKBA - to guaranteed concentrations of at least 10%, while filtering out competitive beta-boswellic acids.

Can I take BosMed Intestinal and BosMed Respiratory together?

Yes. Both formulas use the same high-AKBA purified boswellia base but combine it with distinct secondary essential oils (coriander/fennel/caraway for the digestive tract; thyme/ravintsara/myrtle for the lungs). They can be used simultaneously without exceeding safe botanical thresholds.

Does BosMed interfere with the stomach lining like over-the-counter pain relievers?

No. Over-the-counter NSAIDs block the COX-1 pathway, which is responsible for maintaining the protective stomach lining. BosMed exclusively inhibits the 5-LOX pathway, leaving COX-1 and stomach-protective prostaglandins unaffected.

How quickly does BosMed Respiratory begin working for bronchial support?

Because BosMed Respiratory utilizes lipophilic essential oils (thymol and 1,8-cineole) alongside purified AKBA, the aromatic compounds enter systemic circulation rapidly. Most users report clearer sinus passages and relaxed breathing within 45 to 90 minutes of consumption.

Is BosMed Intestinal suitable for daily, long-term use?

Yes. Unlike high-dose single-compound pharmaceuticals that suppress immune response, BosMed Intestinal acts as an immune modulator and mucosal barrier stabilizer. It is designed for daily maintenance of intestinal wall integrity and healthy gut flora balance.

BosMed 500™

Clinically Studied BosPure® Boswellia

Product Number: 34306 - 60 Softgels Dietary Supplement

Recommendations: 1 softgel, once or twice daily.

SUPPLEMENT FACTS

Serving Size: 1 Softgel Servings Per Container: 60 Amount/Serving Daily Value

Boswellia (Boswellia serrata) Gum Resin Extract (BosPure®) 500 mg **

standardized to contain >70% Total Organic and Boswellic Acids with AKBA >10%, with less than 5% beta-boswellic acids

Other Ingredients: sunflower oil, gelatin, glycerin, sunflower lecithin, purified water, beeswax (yellow), silica, caramel color (softgel), and titanium dioxide.

Contains no: sugar, salt, soy, yeast, wheat, gluten, corn, dairy products, artificial coloring, artificial flavoring, or preservatives.

NON-GMO

BosPure® is a registered trademark of Dolcas-Biotech If pregnant or nursing, consult a health care practitioner before using.

Made in the USA

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