Search Term: " Balancer "
What does GABA Do in the Brain?
November 02, 2011 07:41 AM
GABA or Gamma Amino Butyric Acid is a neurotransmitter of the brain. It is considered to be the main inhibitory brain chemical among mammals. In ordinary terms, it significantly regulates the firing of impulses by the neurons. This chemical is naturally produced by the brain and generally acts as a Balancer together with other neurotransmitters. This neurotransmitter has a key role in the regulation of nerve excitability all throughout the nervous system. It effectively maintains the equilibrium of the body and the brain in excitation status. Chemically speaking, GABA is classified as an amino acid. However, GABA is not a building block of protein like the other amino acids. This is the reason why in the medical field, GABA is rarely considered as an amino acid.
Moreover, GABA is the prime brain chemical responsible for the regulation of muscle tone among humans. In a disorder called Spastic Diplegia, the absorption of GABA into the muscles is weakened because of damage nervous tissues and cells. This would significantly lead to hypertonic muscles in which the muscles will experience spasms and can not anymore recognize and process the neurotransmitter GABA. On the other hand, GABA in insects acts as both inhibitory and excitatory neurotransmitter.
As mentioned above, GABA is an inhibitory neurochemical. It functions at the inhibitory synapses of the brain by attaching to receptor sites in the plasma membrane of both pre – and post – synaptic nerves. Once GABA has bind with the receptor sites, it will cause the ion channels to open and permit either the entry of chloride ion which has a negative charge or exit of potassium ion which has a positive charge. Potassium is the main electrolyte inside the cell. This opening of ion channels will then cause the cell to be either hyperpolarized or re – polarized.
During brain development, GABA also plays a significant role. It significantly controls the proliferation of brain progenitor cells and development of synapses as well as the differentiation and maturation of neurites. Furthermore, GABA is also responsible for the growth and development of embryonic and nerve stem cells. It also activates GABA receptors which lead to the halting of cell cycling in the S – phase. As a result, this will limit the growth of cell thus preventing abnormal growth and even malignancies.
If GABA is in inadequate level, muscle tone is disturbed making it always tensed and the mind will keep on working and working because there is no brain chemical to stop it. Therefore, GABA must be importantly maintained within normal limits.
GABA is naturally produced by nerve cells. However, GABA supplement is now available so that adequate amount of such brain chemical will be administered to the body as needed. GABA supplements can enhance the sleep onset and quality. It can also provide a relaxing feeling and reduce stress and muscle over – activity. Other theories also state that it can regulate mood and behavior thus promoting the total well – being of the person. Ongoing studies are being conducted to show more evidence on GABA’s effect with Human Growth Hormones.
Age Gracefully With Anti Aging Nutrition
January 19, 2008 01:57 PM
With today’s society constantly frowning upon aging and advertisements constantly urging consumers to buy products to tighten, firm, and rejuvenate their skin, our society has placed a very high value on youthful appearances. No one wants to look old, so a natural product to help this is very important. However, just because consumers want to use natural products doesn’t necessarily mean they will, as many wonder if natural products will actually work. Despite some reservation from the consumer, the popularity of all natural anti-aging products is on the rise. Although many products can help minimize signs of aging, companies are starting to recommend the start of preventative skin care regimens in a woman’s late teens.
The key to preventing aging is keeping skin clear, pores unclogged, and you skin moisturized in your twenties so that by the time you reach your thirties, aging is not quite as evident. By age thirty, collagen levels start to reduce, and skin starts to lose its elasticity. It is important to continue a skin care routine and work in some anti-aging products. By age forty and beyond, it’s extremely important to continue the regimen you have build in your thirties while adding an anti-aging serum.
On top of a regular skin care routine, it’s essential for women to use products that contain some level of SPF, which is very important for preventing fine lines, wrinkles, and age spots. Along with SPF, antioxidants are critical in anti aging products, preventing free radical damage and also minimizing facial redness by constricting protecting fine capillaries. Good antioxidant and anti-aging ingredients include blueberries, green tea, ginkgo biloba, cucumber, aloe, lavender, cranberry seed oil, and pomegranate.
Moisturizing the skin is also an anti-aging essential, helping the derma layer provide nourishment and adding cushion to support the skin. A good moisturizer will also help to fight dry skin and wrinkles. Some moisturizing formulas used in Japan have an ability to provide omega essential fatty acids and help to slow the formation of wrinkles. Jojoba, aloe, and avocado oils are also extremely hydrating and effective in the reduction and appearance of fine lines and wrinkles. Since aging can cause the skin to be discolored, there are many products that can help to minimize the appearance of age spots and help to brighten and even out skin tone. A skin tone Balancer, using natural skin lighteners such as kojic acid, lemon extract, and bilberry extract, can stop the process of melanin production and also reduce existing age spots. Sugar cane extract and sugar maple extract act as natural exfoliates, which help to brighten the skin by getting rid of dead skin cells. Night creams containing macadamia nut oil, mulberry bark, and licorice extracts help to firm and brighten the skin and also lighten age spots.
Although natural products are definitely better for consumers’ skin, they often have short shelf lives. In order to fight this, many companies create smaller batches with shorter shelf lives, to make sure that customers will use the entire product before it expires. For retailers to sell anti-aging products and compete with mainstream lines, marketers stress that education is needed to make consumers aware of how great natural skin care is.
Maca is an Adaptogen used for Centuries
November 10, 2007 02:35 PM
Maca has been used for centuries in South American and studied for years by a Dr. Hans Seyle, a Nobel Prize winner on General Adaptation syndrome. The highlanders who live in the Andes Mountains use maca to help them survive and thrive at 14000 to 18000 feet above sea level. Oxygen levels are low at this altitude and maca helps oxygenate the blood. Maca has over 60 phytonutrients to help the body adapt to stress. The unique alkaloids increase the body’s endocrine and immune function.
Maca contains biological active components that spur an aphrodisiac and libido enhancing effect on the body for both men and women. Today’s herbalists suggest maca for a wide range of usages such as hormonal imbalances, PMS, hot flashes, depression and night sweats, and vaginal dryness. Some herbalists recommend maca for chronic fatigue syndrome, adrenal dysfunction, anemia, tuberculosis, and stomach cancer. All would agree that maca extract can be used as an endocrine Balancer and aid in mental clarity.
With all the benefits of maca being discovered, why not give maca a try for your self?
ALPHA GPC - Improves Mental Performance
June 28, 2005 06:21 PM
The quality of our life experience—and our ability to live life to the fullest—is a direct result of optimal brain function. Only a few years ago, nothing could be done to stem the tide of poor circulation, forgetfulness and “mental fog.” But neurological science exploration has identified a fundamental brain compound critical to attention, learning, memory, and even the higher cognitive functions of reasoning and intuition. Research confirms that L-alpha-glycerylphosphorylcholine (called Alpha-GPC for convenience) is crucial to neuronal function and structure. Derived from purified soy lecithin, Source Naturals ALPHA-GPC readily converts to acetylcholine in the brain, helping to maintain neuronal structure integrity. Source Naturals provides an easy and convenient means to profoundly impact the very nexus of our body and mind.
GPC Is Unique
No other nutritional compound comes close to GPC in its ability to boost critically important acetylcholine levels. Found in both the brain and the peripheral nervous system (including the nerve-muscle junctions), acetylcholine is a key nerve messenger molecule, or neurotransmitter. Aging brains are characterized by functional deficiencies in both acetylcholine and its cholinergic receptors. GPC is a highly bioavailable supplement that boosts acetylcholine levels to improve cognitive function. It is also a major choline reservoir, helping to protect the brain against damage from poor circulation and potentially toxic metabolites.
Deficiencies in acetylcholine can cause the body to break down phosphatidylcholine for its choline content, leading to the death of brain cells. Yet in controlled clinical trials of middle-aged subjects taking GPC, reaction time was enhanced and there was improved energy generation and electrical coordination in the brain. For older subjects, double-blind trials demonstrated that GPC had superior benefits over certain other brain nutrients for mental focus, recall, verbal fluency—a unique, marked overall enhancement of mental performance. GPC is an example of what the great Linus Pauling referred to as “orthomolecules,” that is, molecules that are “orthodox” or “correct” for the body. GPC excels as a protective nutraceutical for memory loss and mood enhancement. It protects cells of the brain (and other organs) from damage, shielding a range of important biomolecules against toxin build-up.
Extensive Clinical Testing
In clinical trials that involved more than 5,000 patients, GPC showed marked improvement in overall brain performance. Depending on the particular trial, 50-70 percent of the patients who received GPC had their mental functions improved to a degree “meaningful to life quality.” GPC has shown revitalizing effects on the declining brain, and preliminary evidence suggests GPC may act on the pituitary gland to partially restore its capacity to make vital for cell maintenance and longevity. Other unique brain features of GPC are its benefits for attention and recall in young healthy adults, and its superior bioavailability. GPC readily crosses the bloodbrain barrier to raise brain choline levels within a few hours following oral intake. GPC helps with body-mind integration by being a ready reservoir for acetylcholine. This neurotransmitter is ubiquitous in brain circuit maturation, expansion, renewal and repair, as well as in the “agility” or adjustments of the circuitry that occur during adult life. In addition, an animal study has shown that GPC increases the release of GABA (gamma-aminobutyric acid), the most important and abundant inhibitory neurotransmitter in the brain. It acts as a “Balancer” for the brain and helps induce relaxation and sleep. Without sufficient GABA, neurons fire at random, unable to make sense of incoming signals. GABA helps minimize “neural noise,” making it easier to focus and concentrate.
Why you should take GPC:
PREGNENOLONE - The Balancing Hormone
June 04, 2005 01:40 PM
Hormones are potent regulators of the most intricate biochemical functions involved in our metabolism, growth, development, emotion and behavior. For our bodies to function properly, our hormones must be in balance with one another. But aging, stress and environmental factors can contribute to hormonal imbalances, with serious impact on our well-being. Today, science has rediscovered a beneficial hormone with the capacity to reduce stress, fatigue and support mental alertness. This hormone is broad – spectrum in its influences - with the ability to balance the levels of other hormones in our bodies. Unfortunately, our production of this hormone declines as we grow older - suggesting the desirability of supplementation. Introducing: Source Naturals PREGNENOLONE.
A Wide Range of Beneficial Properties
Pregnenolone - a hormone produced from cholesterol in our adrenal glands, liver, skin, testicles, ovaries, and brain - was the subject of intense interest in the 1940’s. Some of the earliest studies, performed by well-known researcher Hans Selye, found it to be helpful in reducing stress and fatigue. Additional studies were conducted throughout the decade, with positive results. Pregnenolone supplementation was found to benefit people who were under excessive stress. It also was reported to support joint and tissue function and to contribute to skin elasticity. Pregnenolone is believed to affect stress levels through its influence on the adrenal glands, which produce more steroid hormones when people are under stress. Pregnenolone may also affect brain chemistry in beneficial ways. It has been found to inhibit the GABA receptors in brain cells - which may result in increased mental alertness. It may also stimulate the NMDA (N-methyl-D-aspartate) receptors, which play an important role in regulating synapses, thus influencing learning and memory.
Pregnenolone: The Unique Hormone
Much of the current interest in pregnenolone is related to its role as “the grandmother of all steroid hormones.” Pregnenolone is the starting point from which all steroid hormones are manufactured in our bodies. As a “hormone Balancer,” it has the capacity to increase the levels of steroid hormones that are deficient in our bodies and to reduce the levels of excess circulating hormones. Some scientists believe pregnenolone is converted into other hormones only as they are needed by our bodies. The conversion of pregnenolone follows different pathways, depending upon cellular requirements. Pregnenolone may be converted into DHEA (dehydroepiandrosterone), which in turn can be changed into androgens (including testosterone), estrogens and other steroids; or, it may be converted into any or all of a chain of hormones including progesterone, corticosterone, and aldosterone. These characteristics make pregnenolone unique. Because cells may only convert pregnenolone into other hormones on an “as needed” basis, pregnenolone may correct imbalances in the levels of some hormones, without affecting others. This is a great advantage over steroid hormones like DHEA, which may create excess estrogen and testosterone. Pregnenolone is also distinctive because of the innumerable bodily activities it can influence. As a steroid hormone precursor, it is believed to be involved in every biochemical action exhibited by any steroid hormone. This means it may impact memory, mental alertness, stress responses, female reproductive cycles, the body’s natural defenses, and joint and tissue function. With such a wide spectrum of involvement, the potential uses of pregnenolone could be boundless. Source Naturals PREGNENOLONE is available in 10 mg sublinguals and tablets, as well as in 25 mg tablets. All potencies are sold in 60 and 120 tablet bottles.