PREGNENOLONE - The Balancing Hormone

old message PREGNENOLONE - The Balancing Hormone Darrell Miller 06/04/05

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Date: June 04, 2005 01:40 PM
Subject: PREGNENOLONE - The Balancing Hormone


Hormones are potent regulators of the most intricate biochemical functions involved in our metabolism, growth, development, emotion and behavior. For our bodies to function properly, our hormones must be in balance with one another. But aging, stress and environmental factors can contribute to hormonal imbalances, with serious impact on our well-being. Today, science has rediscovered a beneficial hormone with the capacity to reduce stress, fatigue and support mental alertness. This hormone is broad – spectrum in its influences - with the ability to balance the levels of other hormones in our bodies. Unfortunately, our production of this hormone declines as we grow older - suggesting the desirability of supplementation. Introducing: Source Naturals PREGNENOLONE.

A Wide Range of Beneficial Properties

Pregnenolone - a hormone produced from cholesterol in our adrenal glands, liver, skin, testicles, ovaries, and brain - was the subject of intense interest in the 1940’s. Some of the earliest studies, performed by well-known researcher Hans Selye, found it to be helpful in reducing stress and fatigue. Additional studies were conducted throughout the decade, with positive results. Pregnenolone supplementation was found to benefit people who were under excessive stress. It also was reported to support joint and tissue function and to contribute to skin elasticity. Pregnenolone is believed to affect stress levels through its influence on the adrenal glands, which produce more steroid hormones when people are under stress. Pregnenolone may also affect brain chemistry in beneficial ways. It has been found to inhibit the GABA receptors in brain cells - which may result in increased mental alertness. It may also stimulate the NMDA (N-methyl-D-aspartate) receptors, which play an important role in regulating synapses, thus influencing learning and memory.

Pregnenolone: The Unique Hormone

Much of the current interest in pregnenolone is related to its role as “the grandmother of all steroid hormones.” Pregnenolone is the starting point from which all steroid hormones are manufactured in our bodies. As a “hormone balancer,” it has the capacity to increase the levels of steroid hormones that are deficient in our bodies and to reduce the levels of excess circulating hormones. Some scientists believe pregnenolone is converted into other hormones only as they are needed by our bodies. The conversion of pregnenolone follows different pathways, depending upon cellular requirements. Pregnenolone may be converted into DHEA (dehydroepiandrosterone), which in turn can be changed into androgens (including testosterone), estrogens and other steroids; or, it may be converted into any or all of a chain of hormones including progesterone, corticosterone, and aldosterone. These characteristics make pregnenolone unique. Because cells may only convert pregnenolone into other hormones on an “as needed” basis, pregnenolone may correct imbalances in the levels of some hormones, without affecting others. This is a great advantage over steroid hormones like DHEA, which may create excess estrogen and testosterone. Pregnenolone is also distinctive because of the innumerable bodily activities it can influence. As a steroid hormone precursor, it is believed to be involved in every biochemical action exhibited by any steroid hormone. This means it may impact memory, mental alertness, stress responses, female reproductive cycles, the body’s natural defenses, and joint and tissue function. With such a wide spectrum of involvement, the potential uses of pregnenolone could be boundless. Source Naturals PREGNENOLONE is available in 10 mg sublinguals and tablets, as well as in 25 mg tablets. All potencies are sold in 60 and 120 tablet bottles.

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