Search Term: " Lacis "
Bifidobacterium Lactis: The Bacterium That Could Help You LoseWeight & Fight Inflammation
October 10, 2018 03:26 PM
The probiotic Bifidobacterium lactis, or B. lactis, is a powerhouse for gut health. Why is this strain of bacteria so important? One study published in 2015 showed that B. lactis could improve unpleasant and painful symptoms associated with poor gut motility, dysbiosis, and GI hypersensitivity. B. lactis is definitely one of the “good guys” of the gut bacteria world because it contributes to a healthy and balanced microbiome, which positively affects balanced blood sugar and optimal weight maintenance.
"A particular strain of B. lactis, known as HN019, has been shown to have a significant impact on those with metabolic syndrome. This probiotic had beneficial effects on inflammation, nitric oxide metabolites, and antioxidant measurements, and the authors of the study stated that if their results are confirmed, supplementation with this probiotic should be considered further."
Read more: https://www.mindbodygreen.com/articles/bifidobacterium-lactis-weight-loss-inflammation
Where And What Sources Can I Get Probiotics From?
October 11, 2011 12:37 PM
Where Can I Get Probiotics From?
Probiotics are not uncommon to the ear ordinary individuals. You may have heard this term on TV and radio or have read this on a newspaper or internet article. Probiotics are considered to be live microorganisms which pose many benefits to human health especially to the digestive system. According to the World Health Organization, Probiotics: "live microorganisms which when consummed in adequate amounts have a health benefit to the host." Probiotics is a general term. The widely used types of Probiotics include Lactic acid bacteria and bifidobacteria and their different species and strains.
Another good Probiotic is not a bacteria but yeast called Saccharomyces boulardii. Though it may be a different microorganism, but still it offers positive health effects. These beneficial microorganisms are commonly supplied to the body by eating fermented food items such as yogurt and soy yogurt. There are also some fermented products which are specially added with live active good bacteria to improve the health of the gastric environment.
Probiotics are found to be beneficial to the body because of its ability to significantly improve the intestinal microbial balance. It acts by inhibiting harmful microorganisms and toxin - producing bacteria inside the gastrointestinal system from causing harm to the body. These microorganisms also aid the good bacteria which are naturally found inside the gastrointestinal system of the human body.
Probiotics can be acquired from food or dietary supplements. The food items which are considered to be great sources of Probiotics are yogurt, fermented milk, miso, tempeh, soy and soy products as well as certain juices. Other great sources of Probiotics include Aged cheese, Cottage cheese, beer, kefir, pickled ginger, brine– cured pickles, Sauerkraut and certain kinds of wine. Dairy products aside from fermented milk which are rich in Probiotics include acidophilus milk and buttermilk. These dairy products are also fermented and cultured with the potent Probiotics Lactobacillus acidophilus and Streptococcus lactis, respectively. Dietary supplements of Probiotics may come in the form of capsules, tablets or powders. The good bacteria may have been naturally present from the raw material used or added during the formulation of such probiotic dietary supplement.
Keep in mind that Probiotics are different from Prebiotics (Inulin). The latter are indigestible food ingredients which can relatively stimulate the growth and activity of the normal bacterial flora of the intestines. When these two are combined, they form a symbiotic effect by working hand in hand with each other.
Good bacteria are normally present inside our gut system. However, with the effect of certain health conditions and poor lifestyle, these friendly and beneficial microorganisms may be depleted and not reinforced with new healthy ones immediately. This normal bacterial flora of the digestive system is important for maintaining the health of the digestive system thereby improving the general health of the person. These good bacteria are also helpful in inhibiting and regulating the growth of harmful microorganisms found in the digestive system. Instances which can significantly decrease the number of good bacteria in the gut include antibiotic therapy, food poisoning, alcohol intake, stress and poor diet.
Can a Lactase Enzyme Help with Milk Digestion
April 27, 2011 03:49 PM
Lactase enzyme is the compound necessary for the breakdown of lactose. As such, deficiency in this enzyme results in the impaired capacity to metabolize milk and other dairy products. This is quite common in Asian and African countries, where the majority of their populations do not rely on milk-based animal products. Consumptions of lactase supplements have been reported to aid milk digestion.
Human beings are believed to have lost the ability to process lactose in adulthood a few thousand years ago. The primary source of lactose of early human populations was breast milk, which is only provided by mothers during the early stages of childhood in general. This practice has continued in Asian and African communities, the reason why these groups are predominantly lactose intolerant.
On the other hand, European communities have considered milk as an important source of food and nutrition since the introduction of the agricultural practices of raising livestock. It is now postulated that the early inhabitants of Europe who relied so much in dairy products underwent a genetic mutation that enables them to continue the biosynthesis of the enzyme lactase into adulthood.
Whereas much of the global population is lactose intolerant, people with European ancestry are capable of digesting milk well into their adult years. That being said, people who are not lactose intolerant are not necessarily well equipped for the digestion of dairy products. In fact, many adults suffer from lactose maldigestion, which causes gastrointestinal problems like diarrhea and indigestion as well as allergies and sinus problems such as infections.
Lactose maldigestion has a higher incidence worldwide than lactose intolerance. It is a fact that the genetic expression for the enzyme lactase as produced and released in the digestive tract is down-regulated the human body with age. This may not result in lactose intolerance, but depleting levels of lactase will no longer be able to effectively digest into old age food products that contain lactose.
The absence of the enzyme lactase may result in a variety of digestive problems when milk is taken together with other foods. In some people, even the smallest amounts of lactose upset digestion and produce common symptoms of lactose intolerance such as indigestion, diarrhea and sinus inflammation. If you want to avoid these problems but still love dairy products, you may want to choose hydrolyzed lactose.
Lactase supplements have been documented to produce desirable results. Most nutraceutical companies make use of eukaryotic microorganisms that possess the genes needed to synthesize this enzyme, such as Kluyveromyces fragilis, Kluyveromyces lactis, Aspergillus niger, and Aspergillus oryzae, among others. These supplements are formulated for individuals with lactose intolerance, but also benefit those who are suffering from symptoms tied to lactose maldigestion.
The enzyme lactase works on the principle of breaking down lactose into smaller compounds, galactose and glucose, and supplementation of lactase does exactly that.
December 29, 2005 12:06 PM
Did you know that poor digestive function is a contributing factor in more than ninety percent of America’s serious health issues?! The waiting rooms of doctors are jam packed, in part because so many people are suffering with gastrointestinal problems. The medical establishment and alternative health and wellness practitioners don’t always agree, but both sides are certain that a healthy digestive system is the cornerstone of good health. Proteins, the building blocks of life; carbohydrates and fats, your body’s source of energy; vitamins and minerals; and water – all are assimilated through digestion. If you’re not properly digesting the foods you eat, your body isn’t obtaining the nutrients it needs to repair, renew and thrive. Without the raw materials it needs to repair the damage we do to ourselves every day, your body begins to break down, leading to poor health and accelerated aging2,3.
While there are a multitude of factors involved in healthy digestive function, one of the most important is the delicate balance of bacteria found in the human gastrointestinal (GI) tract. There are three main types of flora in the human GI tract - Bifidobacteria, Bacteroides and Eubacterium. Of slightly less importance are Lactobacilli, Streptococci and Peptococci and other transitory flora1. Our stomachs and intestines are populated by hundreds of billions of these bacteria, or microflora. Amazingly, there are more probiotic organisms in our gut than there are cells in our bodies! That’s a lot of bacteria, but it’s GOOD bacteria, and each strain has specific functions in the human body. These bacteria aid the digestion of food and have protective qualities that contribute to good colon health. While a good balance of these different microflora is necessary, there are many factors that can, and do, disrupt this balance –certain medications, a poor diet, infection, stress, bad bacteria, aging and even the climate. The good news is a rapidly expanding body of research suggests that supplementing the diet with the right mix of microflora can have a beneficial affect on gastrointestinal function, and therefore overall health.
NOW® Gr8-Dophilus™ exclusively utilizes the finest strains from Rhodia Incorporated, the world’s leading supplier of high quality probiotic ingredients, and is enteric-coated to ensure that the bacteria in this product are not destroyed in stomach acid but reach the small and large intestines where they are most beneficial. Gr8-Dophilus is a vegetarian product that contains virtually no lactose.
Lactobacillus acidophilus is a well-studied microflora species that’s highly resistant to gastric acidity and is able to proliferate in the presence of bile. Like many probiotic organisms, it also adheres well to intestinal cells, helping to prevent the adherence of certain enteropathogens5.
Lactobacillus casei is a microflora strain that is found in the human mouth and intestines as well as in fermented vegetables, milk and meat. Recent research has shown that this bacterium is active in the GI tract and may help to modulate the immune system*. Research is continuing into this very promising probiotic.
Lactobacillus rhamnosus, like Lactobacillus acidophilus, is highly resistant to gastric acidity and proliferates well in bile. It, too, adheres well to intestinal cells. We’ve included this particular strain because it works extremely well with L. acidophilus. Lactobacillus salivarius is a strain that has proven highly effective against Helicobacter pylori, a bacterial species implicated in a number of digestive conditions. Studies have shown that L. salivarius is capable of producing high amounts of lactic acid, which has been shown to inhibit H. pylori growth in live subjects. Compared to other Lactobacillus strains, L. salivarius was proven to have the greatest inhibitory effect on the proliferation of H. pylori,4 which is why this strain is included in Gr8-Dophilus™.
Streptococcus thermophilus bacterium are isolated from yogurt and are recommended for lactose intolerant individuals to help digest lactose in the intestines. This strain is included in this formula to assist in the acidification of the intestinal environment, as well as to create a favorable environment for lactic acid bacteria.
Bifidobacterium bifidum is one of the workhorses of the large intestine. It has a high tolerance to gastric acidity, and, like L. acidophilus and many other probiotic organisms, it adheres well to intestinal cells, helping to prevent the adherence of certain enteropathogens5.
Bifidobacterium longum is a bifidobacterium of human origin that, like lactobacillus, is extremely resistant to gastric acid and bile salts. Because it’s anaerobic (able to live without oxygen) it’s perfectly suited to colonize the colon. Initial studies have shown that this particular strain of bifidobacteria helps to support the immune system*. It also seems to decrease enzymatic activity in feces. Researchers believe enzymatic activity in feces may contribute to carcinogenesis.
Bifidobacterium lactis is one of the most well-studied strains of probiotic bacteria, with a wealth of peer-reviewed, published research on its benefits. Clinical trials on B. lactis have shown it to be helpful in a number of digestive conditions, including diarrhea and lactose intolerance, as well as immune response modulation.
May 12, 2005 09:33 AM
Keeping the Intestines Healthy"Friendly Bacteria" Therapy Breakthrough
by Richard Conant, L.Ac., C.N.
Ninety percent of the cells found in the human body are not of human origin.
No, this does not mean we are all products of some sinister alien experiment.
The human body is made up of about 10 trillion cells. This huge number is dwarfed by the bacteria we all carry around in our intestinal tracts. The lower bowel is a campground for roughly 100 trillion bacteria, single-celled plant organisms that can be seen only through a microscope.
When we enjoy good intestinal health, the bulk of these bacteria are beneficial. Known as "friendly flora," these tiny guests help digest our food by breaking down undigested proteins, fats and carbohydrates. The friendliest of the friendly bacteria are the "lactobacilli," so named because they produce lactic acid in the bowel, by fermenting carbohydrates. This lactic acid production is profoundly important for keep the intestines healthy. And good intestinal health is the foundation of overall health.
How do we maintain a thriving population of lactic acid-producing bacteria in the gut? First introduced into the human body through mother's milk, lactobacilli are somewhat fragile. Stress, poor diets, and antibiotics can kill them off. They should be replanted fairly regularly throughout life. One way to do this is through consumption of cultured milk products such as sour milk, kefir and yogurt, which contain live lactobacilli. They can also be consumed in dietary supplements, but this may or may not be a reliable route. Bacterial products do not keep very well on the shelf, they require refrigeration, and are largely destroyed on the trip from the mouth to the gut by our own digestive juices.
Introducing Lactobacillus sporogenes- a revolutionary new friendly bacteria supplement.
This article will focus on one particular species of lactobacilli, a relatively unknown member of the family called Lactobacillus sporogenes. This lactic-acid producing bacteria may prove to be one of the most practical forms for use in supplements, thanks to a unique property not shared by the more well-known friendly flora such as acidophillus. L. Sporogenes is a spore-forming bacteria. Safely enclosed within a spore coat that protects it from the environment, L. sporogenes is resistant to heat, oxygen and digestive acids. Once L. sporogenes reaches the intestines, its spore coat dissolves, freeing the bacteria to multiply and churn out the beneficial lactic acid. (The spore coat, made up of a calcium-protein-carbohydrate complex, is harmless).1
The difficulty of keeping friendly bacteria supplements alive is an ongoing problem for manufacturers of these products. Studies have analyzed various commerical products claiming to contain acidophilus and found they often contain few live bacteria.2,3 L. Sporogenes is naturally microencapsulated; this insulates it from the gauntlet through which friendly bacteria in dietary supplements must pass.1 Autointoxication-Poisoning by Bacterial Toxins The intestinal tract may also play host to pathogenic, or disease-causing bacteria. These "unfriendly flora" cause putrefaction and release injurious toxins into the lower bowel. This healthy picture is all too common, and has long been concern of wholistic health practitioners.
The concept of "autointoxication," poisoning of the body by intestinal toxins, was popular among doctors in the late 19th and early 20th centuries. An editorial on the dangers of autointoxication which appeared in the June 3, 1893 issue of the Journal of the American Medical Association (JAMA) declared that "most likely a large majority of chronic diseases take their origin from this cause."4 The famous Russian physician Eli Metchnikoff pioneered the use of lactobacteria for preventing autointoxication and restoring bowel health. His landmark work 'Prolongation of Life' sparked interest in lactobacilli as a food supplement.5,6
Naturopathy, widely practiced during the early twentieth century, has always stressed the fundamental importance of bowel cleansing. With the advent of so-called "scientific medicine," naturopathy slipped into decline, and the concept of autointoxication was discredited. Over the last thirty years or so, this has changed. Naturopathic medicine has rebounded, and the importance of bowel health is once again recognized. A paper published in the New England Journal of Medicine in 1964, while opining that autointoxication "was exploited by quacks and faddists" in the early 1900's concedes that "the concept of autointoxication must now receive serious consideration."7
Leaders in the rebirth of natural medicine such as Dr. Bernard Jensen have helped educate the public about the importance of keeping the bowels healthy through regular use of lactobacilli. Jensen is well-known for his extensive studies of regions such as the Hunza Valley in Pakistan where people commonly live well over one hundred years. Jensen and others have noted that the consumption of fermented dairy products containing lactobacilli is a common dietary practice in these areas. Their observations have contributed to the popularity of friendly bacteria supplements. At the same time, clinical research has provided ample evidence of the beneficial effects of lactobacteria supplementation.5,9<.sup>
Eubiosis-Keeping a Healthy Bacteria Population in the Intestinal Tract
In his book 'Tissue Cleansing Through Bowel Management, which contains a wealth of valuable wisdom on intestinal health, Dr. Jensen writes, "Where health and vitality are found, we invariably find the friendly and beneficial microbes ... To a large extent the flora in the bowel determines the state of health in an individual."8 In a healthy bowel the friendly flora make up the bulk of the bacteria population. The unfriendly, disease-causing organisms are in the minority. The good bacteria keep them firmly under control. This healthy microbial balance in the gut is called "eubiosis."
Life in our modern industrial society is hardly favorable to eubiosis. Residents of the Hunza Valley lead unhurried lives in a pristine, pollution-free environment. They grow their own food in fertile, nutrient-rich soil, work close to the landÐand consume lactic-acid producing bacteria on a daily basis. For the rest of us who cannot hope to enjoy this enviable lifestyle, eubiosis is something we should never take for granted. This means taking proactive steps to plant the seeds of health in our intestinal garden, by using a viable friendly bacteria supplement.
Supplements which help to populate the intestinal tract with friendly bacteria are known as "probiotics." The term "probiotic" literally means "for life.' (In contrast, "antibiotic" means "against life.") Probiotics restore the natural state of "eubiosis" that is so very important for health and longevity.
L. Sporogenes-an ideal probiotic
Not every species of lactobacilli qualifies as an effective probiotic. As noted above, many do not survive processing, storage and passage through the digestive system very well. The following attributes make L. Sporogenes an ideal probiotic supplement:1,10,11
1) Naturally microencapsulatedÐstable at room temperature and can be stored unrefrigerated for long periods without loss of viable organisms.
2) Tolerates heat, stomach acid and bile, allowing it to successfully travel into the lower bowel.
3) Non-pathogenic, has only beneficial effects on its host. Has similar characteristics as acidophilus: prefers a mild acid environment; produces lactic acid, digestive enzymes, etc.
4) Readily multiplies in the human gut. In the stomach, the spore coat absorbs moisture and begins to swell. Upon reaching the small intestine, the bacteria cells germinate and begin to multiply, doubling in number every 30 minutes.
5) Produces enzymes which help digest protein, fats and carbohydrates. These enzymes include lactose, the enzyme that digests milk sugar.12
6) Creates a favorable environment (mildly acidic) in the gut for other friendly bacteria to thrive. Prevents overgrowth of pathogenic organisms.
7) Produces lactic acid in the form of L- lactic acid only.
The last point is especially important. Lactic acid occurs in the form of three isomers (substances with identical molecular structures that have different shapes): L-lactic acid, D-lactic acid and DL-lactic acid. The D form is metabolized slowly, and can produce acidosis in the system. (Infants have a particularly difficult time metabolizing D-lactic acid.)11,13 DL-Lactic acid, the kind acidophilus makes, may be converted to either D or L.
The L form is the one we want. L. sporogenes is a "homofermenter," it makes L-lactic acid exclusively. Lactic acid keeps the gut mildly acidic. This acidity is essential for the gut to be a hospitable home for friendly bacteria, and stops the growth of the unwelcome disease-causing bacteria.
L. sporogenes has only one drawback. It is a transient visitor that does not permanently colonize in the digestive tract. A study on the retention of L. sporogenes found no bacteria in the feces six days after consumption was discontinued.14
L. Sporogenes-Results from Clinical Studies
L. Sporogenes is used extensively in Japan and approved by the Japanese equivalent of the FDA. L. sporogenes has been given to hospital patients suffering from intestinal complaints such as gas and bloating due to abnormal fermentation, constipation, diarrhea and indigestion. (These problems often occur after surgery or chemotherapy.) A total of 16 clinical reports are on record in Japanese hospitals, documenting 293 case of digestive complaints treated with L. sporogenes.15 The overall improvement rate is an impressive 86 percent. Results are typically seen within four to five days. L. sporogenes has also been used with success to clear up diarrhea in newborns.16 Like other lactobacilli, L. sporogenes lowers blood cholesterol. (Lactobacilli break down cholesterol and bile salts in the intestinal tract.) Researchers at a hospital in New Delhi, India gave L. sporogenes tablets to 20 patients with high cholesterol for twelve weeks.17 Total cholesterol levels were substantially reduced, along with LDL cholesterol, and the beneficial HDL rose slightly.
The popularity of L. sporogenes in other countries as an ideal friendly bacteria supplement will no doubt be soon matched in the U.S. This microscopic helper for intestinal health is now sold in probiotic products under the name "Lactospore®."
1. Gandhi, A.B., Nagarathnam, T. Probiotics in veterinary use. Poultry Guide 1990;27(3):43-47.
2. Brennan, M., Wanismail, B., Ray, B. Prevalence of viable Lactobacillus acidophilus in dried commercial products. Journal of Food Protection 1983;46(10):887-92.
3. Gilliland, S.E., Speck, M.L. Enumeration and identity of lactobacilli in dietary products. Journal of Food Protection 1977;40(11):760-62.
4. Dalton, R.H. The limit of human Life, and how to live long. JAMA 1893;20:599-600.
5. Shahani, K.M., Ayebo, A.D. Role of dietary lactobacilli in gastrointestinal microecology. American Journal of Clinical Nutrition 1980;33:2448-57.
6. Metchnikoff, E.. Prolongation of Life. New York: G.P. Putnam Sons;1908.
7. Donaldson, R.M. Normal Bacterial populations of the intestine and their relation to intestinal function. New Eng. J. Med. 1964;270(18):938-45.
8. Jensen, B. Tissue Cleansing Through Bowel Management. Escondido, CA: publ. by Bernard Jensen, D.C.;1980.
9. Schauss, A.G. Lactobacillus acidophilus: method of action, clinical application, and toxicity data. Journal of Advancement in Medicine 1990;3(3):163-78.
10. 'General InformationÐLactospore®' 1996; Sabinsa Corporation: Piscataway, NJ.
11. Gandhi, A.B. Lactobacillus sporogenes, An Advancement in Lactobacillus Therapy. The Eastern Pharmacist August 1998:41-44.
12. Kim, Y.M., Lee, J.C., Choi, Y.J., Yang, H.C. Studies on the production of beta galactosidase by lactobacillus sporogenes. Properties and application of beta galactosidase. Korean J. Appl. Microbiol. Bioeng. 1985;13(4):355-60.
13. Oh, MS. D-Lactic acidosis in a man with short bowel syndrome. New Eng J Med 1979;31(5):249-52.
14. Hashimo, K. et. al. New Drugs and Clinics 1964;13(9):53-66.
15. 'Abstracts of papers on the clinical studies of Lacbon' Unpublished data.
16. Dhongade, R.K., Anjaneyule, R. Lactobacillus sporogenes (Sporlac) in neonatal diarrhea. Unpublished data.
17. Mohan, J.C., Arora, R., Khaliullah, M. Preliminary observations on effect of Lactobacillus sporogenes on serum lipid levels in hypercholesterolemic patients. Indian J. Med. Res. 1990;92(B):431-32.
VitaNet ® Staff