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How to deal with Stress and Cortisol...
August 30, 2006 09:36 AM
Beating the Aging Odds
All of us grow older, but aging is a choice. You have it in your power to retain much of the health, vitality and beauty of your youth. It boils down to a simple fact – retard oxidative stress and you’ll retard the aging process. The 70 million people who make up the “boomer” generation and are getting ready for an active retirement welcome this news.
Stress and Cortisol
The early twentieth century “stress doctor” Hans Selye, M.D. was renowned for his work on the human adaptive response and the effects of stress on aging. He taught that every stress leanves an indelible scar, and the organism pays for its survival after a stressful situation by becoming a little older. That’s because stress raises levels of the adrenal hormone cortisol. It increases internal generation of free radicals, disrupts normal metabolism and leads to aging conditions. Because of this, cortisol has been dubbed the age-accelerating hormone.
The more stressful our lifestyle and the level of environmental hazards we are exposed to, the higher cortisol levels will climb in an effort to jump-start our adaptive response. Coupled with a poor diet, this is a recipe for pre-mature aging. At least eleven major aging factors are related to high cortisol levels:
So, there you have it. Now let’s see how to tame cortisol and reduce oxidative stress.
Reducing Cortisol and Oxidative Stress
Be in the moment – stress reducing techniques such as meditation, prayer, visualization, yoga, chi gong, and listening to inspirational tapes induce calmness and a sense of balance.
Eat right for your genes – as we get older, we don’t digest animal protein as efficiently as when younger. Shifting to plant source proteins that are easier to digest and contain the full complement of vitamins and minerals is most desirable. We are accustomed to thinking of dairy, meat, poultry, and fish as “protein.” All vegetables are good sources of protein. Along with legumes, whole grains, and nuts, daily protein needs are easily fulfilled. Meals that combine a variety of tastes from plant foods also require less salt for flavor enhancement and this helps keep hypertension at bay. So, explore just how good meals can be that either do not contain meat or use it as a condiment. If you do need some salt, try substituting table salt with NOW Vitamins Potassium Chloride crystals.
Enzymes Increase Digestion
Use digestive enzymes such as Optimal Digestive System to insure that you are absorbing all the nutrients in your food. This product has been clinically tested for its digestive effectiveness helping to digest fats, carbs, proteins and even gas producing beans and cruciferous vegetables. Other enzymes, Serrazimes is a systemic enzyme that will help keep lymphatic’s clear of debris, support immune function, and boost your adaptive response to stress.
As many people reach middle age they have a tendency to gain weight around the navel. High stress amps up levels of cortisol that results in increased girth. Middle body fat is considered a significant risk factor for impaired glucose metabolism and cardiovascular disease. Check your waist to hip ratio by dividing your waist measurement in inches by your hip measurement. If you have a ratio of 0.85 or below, you have lower risk of insulin resistance and cardiovascular disease. This measurement is one of the best indicators of cortisol induced metabolic syndrome and weight gain.
Super cortisol support with Relora is an herbal, vitamin and mineral formula that’s designed to fight mid-body fat by taming cortisol. Its key ingredient is Relora which is a blend of the herbal extract of Phellodendron amurense and Magnolia officinalis. A small double blind clinical trial found that pre-menopausal obese women – half of whom took Relora – lost a significant amount of weight. These were women who eat in response to stress. Thus the researchers proposed that Relora appeared to reduce cortisol and perceived stress, resulting in weight loss. Super cortisol support also contains Ashwagandha and Rhodiola, herbs traditionally use for increasing adaptive response and reducing stress. You can read about these herbs and other nutritional products in the book 7-syndrome healing: supplement essentials for mind and body. Written by myself and coauthor Jayson Kroner. This book can be ordered from Now Foods.
Additionally, Chinese scientists found that the active components in Relora called honokiol and magnolol delayed gastric emptying, which would make you feel full longer. An additional anti-aging benefit was observed by another group of Chinese scientists. They reported that honokiol is a potent arterial thrombosis inhibitor because it inhibits prostacyclin release; a promoter of platelet adhesion. Platelet stickiness increases stroke risk. Phellodendron and Magnolia have been used in Chinese medicine for centuries.
Quell Free Radicals
Health and longevity essentially rests on the body balance between free radical load and antioxidant reserves. Toxic exposure depletes some of your antioxidant reserves. Eating a diet rich in antioxidant fruits, vegetables, legumes and grains, helps you rebound. Continued toxic exposure will challenge your antioxidant status and may overwhelm your reserves. VitaBerry Plus+ is a powerful antioxidant formula that contains a range of high ORAC fruits that naturally augment the diet. ORAC stands for oxygen radical absorbance capacity. It is a measure of the ability of a food to quell oxygen free radicals, the most dangerous kind. VitaBerry Plus+ is a product after my own heart. In my book The Anti-Aging Solution, I wrote about how different color foods protect DNA and prevent aging. VitaBerry Plus+ contains the important colors described in my bood. You can order your copy from Now Vitamins.
True-E Bio Complex rounds out the antioxidant colors. It contains all eight tocopherols and eight tocotrienols in the natural ratio found in “tan” foods such as whole grains and legumes. It is the only natural vitamin E that is produced from soy that has not been genetically modified.
The best anti-aging advice I can pass on is from my friend and food columnist Joan Jackson. “Take Pleasure in Your Life TODAY and Enjoy What You Eat”
Doctor’s Corner - Relora: Minimizes Stress-Induced Eating
August 09, 2006 01:56 PM
Relora is a proprietary all-natural botanical product developed by Next Pharmaceuticals, Inc. it contains ingredients extracted from two plant species that have been used in traditional Chinese herbalism for over 1500 years. These are patented extract from Magnolia officinalis (US Patent No: US 6,582,735) and a patent-pending extract from Phellodendron amurense.
Relora helps relieve stress, anxiety and minimize stress-induced eating, which in turn may help to produce weight loss when used as part of a healthy diet and exercise plan. The research and development of Relora involved sophisticated testing and screening for ingredients that have anti-anxiety properties, but no daytime sedative effects. Initially, investigators tested the Magnoliaceae plant family as a lead source of new anti-anxiety products. Scientists first focused on two phytochemicals on constituents in the plant that have “bio-activity” (work positively on the body)—magnolol and honokiol. Through a series of studies, it became clear that Relora was a safe and effective formulation.
Relora works with the body’s natural chemistry to maintain normal levels of stress hormones. These hormones not only affect emotional well-being, but can also have a major impact on appetite and how the body stores and metabolizes fat. By working to re-establish a stable balance of these hormones, Relora can help break the stress/weight cycle and restore optimum health to the mind and body.
In addition to normalizing stress hormones, Relora has been shown to control anxiety and the symptoms associated with it: irritability, emotional ups and downs, restlessness, tense muscles, poor sleep, fatigue and difficulty concentrating. Daytime sedation often occurs with products that induce relaxation. Not with Relora! This breakthrough botanical provides all the anti-anxiety benefits without inducing daytime sedation. In central nervous system receptor binding assays, the plant extracts in Relora bind to several important targets associated with anxiety. Also if interested, the bark of magnolia officinalis has been used in traditional Chinese herbalism for centuries for stress induced muscular tension.
Relora, Stress and Weight Loss
Stress is reported to play a significant role in a wide variety of health conditions. Recent work with the National Institutes of Health (NIH) and other major research centers has demonstrated that stress is a significant contributor to immune dysfunction, cardiovascular challenges, other age-related imbalances, and excess body fat. This type of fat is related to stress-induced hormone imbalances, especially imbalances of the hormones cortisol and DHEA. Until now, the only course of action for losing this fat has been stress reduction with exercise and diet, and anyone who has attempted diet and exercise alone often encounters a long, troublesome road. Relora may help the body normalize cortisol and DHEA levels in stressed individuals while inducing relaxation, and act as an aid in controlling weight and stress-related eating.
The increase in cortisol levels signals the brain that the body is in stress, causing food cravings, especially for high-fat, high-sugar foods. These foods, in turn, cause additional stress, thereby fueling the stress-cortisol cycle. Eventually, more fat is stored than the body needs unless sufficient exercise is in place to compensate, or the stress is reduced.
The ingredients in Relora are key supplements that help the adrenal glands to “come back to life” by reducing the excessive stress hormone response in the body and reducing carbohydrate craving behavior.
Results from Human Trials with Relora
Relora was tested at the Living Longer Institute in Cincinnati, OH and found to be safe, effective, rapid acting, non-sedating dietary supplement that helps control occasional mild anxiety. Three hundred forty five female subjects were administered Relora for 2 weeks. The dosage was 200mg of Relora three times daily. Eighty nine percent of the subjects reported that Relora helped them relax, while 78% found Relora to help prevent stress-related eating.
A second trial was undertaken at the Living Longer Institute to measure cortisol and DHEA levels in patients with mild to moderate stress. Elevated cortisol levels and depressed DHEA levels are associated with chronic stress. A two week regimen of Relora produced a significant increase in salivary DHEA (227%) and a significant decrease in morning salivary cortisol levels (37%). These findings support Relora’s ability to relieve stress and its potential role in weight control and stress-related eating behavior.
A third study was completed in late 2002 that evaluated Relora on its ability to improve snacking habits in people who snack on sweets or eat salty snacks when they are under excessive stress. Forty nine subjects were evaluated and it was found that Relora cur sweet snacking in the sweet cravers by 75%! It cut snacking on salty snacks by 50%. Seventy three percent of all individuals in the study reported feeling less stressed while taking Relora.
A double-blind placebo-controlled study was completed in January, 2004. forty premenopausal women were evaluated for stress, anxiety, food intake and weight management. Relora significantly reduced anxiety and prevented weight gain. A significant weight gain occurred in the placebo group while either now weight gain or weight loss occurred in the Relora group.
Suggested Use and Safety
Relora is designed for adults. The suggested daily dose is 1 capsule (250mg) 2 – 3 times per day. Relora is not recommended for persons under the age of 18. if you are pregnant, nursing or taking a prescription drug, consult a health practitioner prior to use.
Dr. James B. LaValle, R.Ph., N.M.D., C.C.N. is a licensed pharmacist (University of Cincinnati College of Pharmacy), certified clinical nutritionist (International & American Associations of Clinical Nutritionists), and doctor of naturopathic medicine (Central States College of Health Sciences, IAACN), with more than 18 years clinical practice experience in the field of natural therapeutics and functional medicine. Dr. LaValle is in clinical practice at the Living Longer Institute, a comprehensive wellness, prevention, and early detection program he co-founded. He sits on various scientific advisory boards within the dietary supplement industry. LaValle is also an adjunct professor in the college of pharmacy at The University of Cincinnati and serves as a preceptor in the Department of family Medicine, University of Cincinnati College of Medicine.
Super Cortisol Support Fact Sheet
December 08, 2005 07:04 PM
Super Cortisol Support Fact SheetNeil E. Levin, CCN, DANLA 10/1/05
LIKELY USERS: People under a lot of stress; People who suffer from stress-related eating; People who may have metabolic syndrome (Syndrome X);
KEY INGREDIENTS: Relora®13, Rhodiola14-20, Reishi 21-24, Green Tea Extract25-32, Holy Basil, Ashwaganda, Banaba, Pantothenic Acid, Calcium Ascorbate, Magnesium, Lecithin, Chromium
MAIN PRODUCT FEATURES: NOW® Super Cortisol Support is an herbal and nutritional formula designed to support healthy adrenal function and maintain healthy cortisol levels. The adrenal glands help the body respond and adjust to stress generated from both internal and external forces. Under chronic stress, cortisol can be overproduced, resulting in weight gain and difficulty in managing healthy blood sugar levels. Super Cortisol Support combines adaptogenic herbs with Chromium, Corosolic Acid and Relora® to help the body manage the negative effects of stress such as abdominal obesity, overeating and low energy levels.
ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES:
Reishi, Rhodiola, Ashwaganda, and Holy Basil support healthy energy levels throughout the day1-6. Reishi, Rhodiola, Ashwaganda, and Holy Basil support healthy immunity1-9. Along with Chromium, and Corosolic Acid, these herbs also help to support healthy serum glucose levels1-12. Relora® has been included in this formula to alleviate symptoms associated with stress such as irritability and nervous tension13.
This formula is recommended by Hyla Cass, MD.
This is the first Cortisol formula to use Relora®, a natural proprietary blend of a patented (U.S. Patent No. US 6,582,735) extract of Magnolia officinalis and a patent-pending extract from Phellodendron amurense. Relora® was developed as an ingredient for dietary supplements and functional foods that could be used in stress management and for stress-related appetite control. This patented blend of plant extracts is the result of screening more than fifty plant fractions from traditional plant medicines used around the world. Relora® has excellent stress management properties without causing sedation. Overweight adults may have excessive abdominal fat due to stress-related overeating. Relora® appears to maintain healthy hormone levels in stressed individuals and act as an aid in controlling weight and stress-related eating.33
SERVING SIZE & HOW TO TAKE IT: One capsule, two to three times a day.
COMPLEMENTARY PRODUCTS: Holy Basil, Green Tea, L-Theanine, Licorice Root, Vitamin C, Eleuthero Root, Pantothenic acid
SPECIFIC: Some of these ingredients may support the body’s blood sugar controls, so people taking blood sugar medications should inform their physician before using Super Cortisol Support, and their glucose should be monitored when taking this formula so their medication strength can be modulated appropriately to avoid an overdose of medication. No side effects have been noted for this dosage of Relora®.
GENERAL: Pregnant and lactating women, children and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.
Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
1. Spasov AA, Wikman GK, Mandrikov VB, Mironova IA, Neumoin VV (2000) Phytomedicine 7(2):85-89.
NOW is the leader in quality and value
October 21, 2005 08:12 AM
NOW is the leader in quality and value
“We only deal with companies that support the natural products industry and have a strong public service mission”
We couldn’t agree more. NOW has, and will continue to fight for the rights of consumers to take safe supplements. As one of the most active and influential advocates in the natural products industry, we proudly support the following industry organizations.
NFA, Citizens for health, AHPA, OTA, The Herb Research Foundation, The American Botanical Council, Consumers for Health Choice (UK), The GMO Task Force, The GMP Task Force, American Herbal Pharmacopoeia, The Campaign to label Genetically Engineered Foods, AOAC (method validation), AOCS (American Oil Chemist Society), The Dietary Supplement Education Alliance (DSEA), and More…
“Does NOW support any Charitable or public services?”
NOW is a leading recycling company and was awarded a silver medal for nutrition business journal in 2005 for our dedication to environmental and sustainability issues. We use environmental-friendly packaging and procedures to ensure that our impact on the environment is minimal. Here are just a few of the charities and originations NOW generously supports:
Local Heal Clinics and food banks, Salvation Army, Marklund children’s home, African meal-a-day fund, compassion international, vitamin angel, world relief, Indian orphanage, Hephzibah children’s home, nature conservancy, Americas second harvest, world wild life, and many more
Theanine Serene™ with Relora® - to ease tension, improve relaxation
July 07, 2005 03:52 PM
NEW PRODUCT ANNOUNCEMENT
New and Improved!
Relora is a registered trademark of Next Pharmaceuticals.
Suggested Use: 2 tablets daily, or as recommended by your health care professional.
June 30, 2005 09:20 AM
Depression By Ellen J. Kamhi, Ph. D. with Dorie Greenblatt Depression is a widespread health imbalance that effects many people at some point in their lives, and may be caused by a multifaceted list of factors. Depression can be triggered by personal tragedy, loss of a loved one, or changes in life situations (even if they are positive!). Some of the less recognized causes of depression may involve diet, including over-consumption of sugar, artificial sweeteners, chemical flavorings and preservatives, insufficient nutrition and foods that causes an allergic or sensitivity reaction in an individual. Lack of exercise and not enough sunlight, (i.e. Seasonal Affective Disorder), may be implicated as well. It is essential that those suffering from severe depression seek professional care. Since depression can arise from many different sources and operate on multiple levels, it is helpful to remember that “true healing” requires one to explore and address the root cause(s), not just attempt to cover up the symptom. Proper nutrition is essential. B vitamins can be helpful, such as Nature’s Answer’s B-Stress with Herbs, along with other nutrients such as the amino acids, GABA (particularly for anxiety), Tyrosine and Phenylalanine. Regular exercise, and a nice relaxing bath in lavender oil and sea salt are also enjoyable aids for lifting one’s spirits.
Herbs can be useful in relieving the symptoms of mild to moderate depression. Nature’s Answer offers many high-quality, single herb and combination formulas (liquid or capsule) that feature ingredients well-known for balancing emotional mood. Relora®* features a patented propriety blend of two herbs, Magnolia (standardized to 1.5% honokiol (3.75mg)) and Phellodendron (standardized to 0.1% berberine (0.25mg)) which, when combined according to a particular method, may help reduce the negative effects of stress, a factor that leads to depression as well as “stress overeating”. When the body is under stress, it causes the release of specific “stress hormones” that influence mood and emotional well-being. Relora® is unique because its active plant constituents work on the body’s natural chemistry to re-establish a normal equilibrium of stress hormones, while enhancing feelings of relaxation and cheerful outlook.
Another powerful, “all-in-one” proprietary herbal blend formula from Nature’s Answer® is Mood Balance 2™ (alcohol free liquid, vegetarian capsule). Mood Balance 2™ contains key ingredients well-recognized for their beneficial actions on emotional health, including St. John’s Wort, California Spikenard, Gotu Kola, Skullcap and Eleuthero root**. This combination of ingredients can help “lift the spirits”. (Note that these herbs are also available from Nature’s Answer® as single herb formulas in concentrated liquid herbal extracts and/or vegetarian capsules; Kosher).
Key ingredients in Mood Balance 2™include:
St. John’s Wort (Hypericum perforatum), used for a range of nerve disorders and said to “chase away evil spirits.” Since 1996, it has become one of the most popular herbs in the US due to its use as a mild to moderate antidepressant. A number of current studies confirm its effectiveness, including a review in the British Medical Journal of 23 clinical trials, which reported that it worked nearly as well as the leading pharmaceuticals with far fewer side effects. Although more research is needed, it appears that the activity of St. John’s Wort is due to a variety of naturally occurring components, including Hypericin and Hyperforin. Nature’s Answer’s exclusive formula, Super St. John’s Wort (vegetarian capsule), is standardized to both 3.0% hyperforin and 0.3% hypericin. Gotu Kola (Centella asiatica), used for centuries in Ayurvedic medicine as a nerve tonic and to treat emotional upset, insomnia, stress, anxiety and memory problems. It is currently used along with meditation and yoga due to its abilities to both calm and energize nerves. Skullcap (Scutellaria lateriflora) has the double action of relaxing nervous tension while building the central nervous system. As a mild bitter it will also help stimulate digestion and help the liver. Eleuthero root** (Eleutherococcus senticosus) is an “adaptogen” that helps to balance the entire system. It gives strength and fortitude, especially when dealing with stress; so often a factor in depression.
References for Educational Purposes: