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Search Term: " ransdermal "
New Study to Explore Benefits of CBD for Veterans with PTSD   
Date:
June 28, 2017 12:14 PM
There is a Cannabidiol (CBD) study that involves veterans suffering from PTSD, and the effects that the CBD has on them and their trauma. The study is taking place in Florida, under the guidance of Wes Clark jr., a veteran who is passionate about assuring veterans that they can have safe access to cannabis. It is being funded by Alternative Health. Together they hope to bring easier access to CBD as well as sharing their findings with the medical community. Key Takeaways:
"It is unquestionable that veterans receive comfort and relief from cannabis and CBD" Read more: http://terpenesandtesting.com/new-study-explore-benefits-cbd-veterans-ptsd/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4901) Take Charge Of Your Health With Herbal Bio-Identical hormones 
Date:
November 04, 2007 03:17 PM
Bioidentical hormones assist women in overcoming acute menopausal symptoms, while improving skin. They help by strengthening bones, keeping the mind sharp, promoting energy and well-being, and helping to preserve vaginal tone and resist vaginal dryness. In men, these hormones add energy and vitality, while improving muscle tones and mental sharpness. Bioidentical hormones (BHRT) are exact duplicates of the hormones that are produced by the body. However, they are much more easily metabolized by the body into safe forms of estrogen than their counterparts, which stimulate toxic metabolites. When they are used in physiologic amounts, bioidenticals carry much fewer risks than synthetic hormones. However, despite the fact that research supports their use and proves them safe alternatives to prescription drugs, few physicians are actually using these hormones in their practices. Those patients, who wish to address menopausal and andropause symptoms, or to achieve lifelong hormonal balance in order to prevent illness, often do not know where to go to find a comprehensive bioidentical hormone replacement program. Instead, they read whatever they can to formulate a plan and purchase various products that are available over the counter, often spending precious time and money on programs and products that don’t do what they’re expected to do. One of the most common errors among people is putting together a program based solely on symptoms instead of first checking hormone levels. Symptoms may overlap from one hormone pattern to another. If you try to replace or augment specific hormones without having an accurate test of the levels first, your results will seldom be good. If your doctor is prescribing transdermal hormones, make sure to do a saliva self-test to measure your hormones levels as it is much more accurate and revealing than other types of tests. You can submit your samples to Mead Labs, where you will actually receive a telephone consultation from a health professional to interpret your results followed by a program of products prescribed especially for you from one of their medical professionals. With your own results, you can learn a lot about the exact state of your hormones instead of blindly guessing from symptoms which may be similar. For example, men may not need testosterone shots or transdermal patches, as the results may show estrogen dominance. The answer for this is not adding more testosterone, because the man could be converting testosterone into estrogen, but instead a program including special herbs and nutrients may be much more beneficial. No matter your gender, your health professional at Mead Labs will design a safe and effective program based solely on bioidentical hormones, herbs, and nutrients first. In the past years, when prescription, non-bioidentical HRT was used by any women with menopausal symptoms, there was no testing to find out what kind of imbalance was actually occurring. Proponents of BHRT are trying to ensure that this method of prescribing the same combination and amounts of medications to everyone is not used with natural hormones. Because hormone profiles and levels can vary significantly from person to person, even those people in the same gender, testing hormones levels and obtaining recommendations from a medical professional who is experienced in BHRT are the key points to ensure you benefit from this therapy.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1617) California Proposition 65 (Prop 65) and Progesterone Cream Warnings
Date:
February 17, 2006 06:29 PM
Scientific Safety Information on Progesterone California Proposition 65 (Prop 65) and Progesterone Cream Warnings Amy Kosowski, M.S., LDN Prop 65: What is it? Proposition 65, the Safe Drinking Water and Toxic Enforcement Act of 1986 , was enacted as a ballot initiative in the state of California in November of 1986. The Proposition was intended by its authors to protect California citizens and the State's drinking water sources from chemicals known to cause cancer, birth defects or other reproductive harm, and to inform citizens about exposures to such chemicals 1. Proposition 65 requires the Governor to publish, at least annually, a list of chemicals “known to the state to cause cancer or reproductive toxicity .” Progesterone, as well as other human hormones, appear on this list 1. Set forth below is the information that formed the bases for the addition of progesterone to the Prop 65 list by the California Office of Environmental Health Hazard Assessment (“OEHHA”). Prop 65 and Progesterone - Perspective
In August of 2004, OEHHA published a document stating the rationale for the addition of Progesterone to the Prop 65 list 2. This document is a review of human, animal, and in vitro studies that used progesterone, synthetic progestins, and other progestagens (progesterone-like compounds). Experimental data from the use of all of these compounds were mixed together, along with data from studies using other steroid hormone derivatives (mainly synthetic estrogens) and many different methods of administration. Although this review covered the existing scientific literature on progesterone and its many derivative compounds, there are many problems with the type of data analysis that was employed. First, progesterone is endogenous to humans and necessary for bone and reproductive health while progestins and other synthetic progestagens are not. Progestins and progestagens are similar in molecular structure to progesterone, but when they bind to progesterone receptors, their effects are usually much stronger and more likely to cause abnormal physiologic responses 3, 4. Furthermore, the majority of the studies concerning the health effects of these progesterone derivatives involved combinations with synthetic estrogens 2-4. There were very few studies mentioned in the 2004 document that used exclusively bio-identical progesterone (the kind found normally produced by humans as well as that used in progesterone creams), and those studies that did were at supra-physiologic doses (very high). The doses of progesterone ranged from 10-1000 times the dose usually recommended by manufacturers of progesterone creams 2, although in a few cases, the doses were closer to the recommended dosages. The route of administration of progesterone is also at issue. All of the studies cited in the OEHHA document used either oral, injected, or suppository forms of hormones; none was conducted using transdermal creams. This is an important consideration because hormones absorbed through the skin are metabolized differently than hormones that are administered via other routes 5, 6. Putting it Together While the OEHHA Prop 65 reference document on progesterone 2 is a broad survey of the published scientific literature examining the potential effects of the pharmaceutical use of progesterone and its synthetic derivatives, it is not clear at all that these effects would be seen with the use of low-dose progesterone creams. The OEHHA Prop 65 progesterone document evaluates a broad range of information regarding progesterone and synthetic materials that are not natural progesterone. The conclusion reached was not challenged, and it is on that basis that progesterone creams now carry the Prop 65 warning.
1 California OEHHA Web Site: //www.oehha.ca.gov/prop65/p65faq.html . 2 Reproductive and Cancer Hazard Assessment Section, Office of Environmental Health Hazard Assessment, California Environmental Protection Agency (2004) Evidence on the developmental and Reproductive Toxicity of Progesterone. 3 Campagnoli C, Abba C, Ambroggio S, Peris C (2005) Pregnancy, progesterone and progestin in relation to breast cancer risk. J Steroid Biochem Mol Biol 97(5):441-450. 4 Campagnoli C , Clavel-Chapelon F , Kaaks R , Peris C , Berrino F (2005) Progestins and progesterone in hormone replacement therapy and the risk of breast cancer. Steroid Biochem Mol Biol 2005 96(2):95-108. 5 de Lignieres B, Dennerstein L, Backstrom T (1995) Influence of route of administration on progesterone metabolism. Maturitas 21:251-257. 6 Gompel A, et al. (2000) Progestins were also proapoptotic in normal as well as in hormone-dependent breast cancer cells. Steroids 65(10-11):593-598. 7 Bu SZ ( 1997) Progesterone induces apoptosis and up-regulation of p53 expression in human ovarian carcinoma cell lines. Cancer 79(10):1944-50.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1224) Utah's Inland Sea Minerals – Topical Application
Date:
November 22, 2005 09:23 AM
Minerals provide a bounty of healing properties that have scientifically validated their use for topical applications. These applications have been shown to have powerful local and systemic effects. The health of ones skin and hair reflects inner health. Indeed, we judge the health of animals and humans alike by their outward appearance of fur or skin, respectively. The human skin is the largest organ of the body and is highly involved in the detoxification and maintenance processes of health. Skin not only excretes and eliminates toxins; it also has a tremendous capacity to absorb health supportive substances. The pharmaceutical industry frequently takes advantage of the skin’s absorptive capacity with drug therapies. Such therapies include the transdermal delivery of drugs like nicotine, hormone patches, progesterone creams and so forth. Thus, it is apparent that natural therapies can have pronounced and powerful health effects. Clinical researchers have continued to document the clinical findings that have been observed for decades when it comes to the healing properties of topical minerals. Many of the studies on therapeutic baths have used minerals from the Dead Sea, an ancient inland sea. However, a similar and impressive array of minerals occurs in the other inland sea, the Great Salt Lake. Indeed, the high presence of magnesium from both inland seas appears to be the foremost active mineral. A comparison chart below clearly reflects the mineral analysis and similarity (see chart below). The following survey of medical research reflects a few of the many therapeutic roles for mineral salt baths. Of particular interest are the powerful effects of magnesium salts that are prevalent to both Utah’s Inland Sea and the Dead Sea that exhibit favorable effects in inflammatory disease. Arthritis: 103 patients with arthritic symptoms were treated for 1-2 weeks. They received various bath treatments with the ionic trace minerals. The study showed that the higher concentration baths offered the most impressive results. Those with the greatest physical limitation had the most pronounced improvement. Over 80 percent of the patients reported having less pain, 70 percent reported improved mobility and 60 percent were able to decrease analgesic use (i). In a different double-blind study, the use of warm mineral baths with Dead Sea salt demonstrated a lasting effect for patients suffering from degenerative arthritis. (ii) Skin: In a clinical trial conducted by a leading research university in Germany, patients with atopic (eczema) skin disorders immersed their arms in a magnesium chloride rich bath. The participants immersed one arm in tap water the other in the therapeutic magnesium rich bath. The findings showed that skin hydration was improved and skin roughness and inflammation was reduced. The researchers stated “magnesium salts are known to bind water, influence epidermal proliferation and differentiation and enhance barrier repair.” (iii) Another study showed that magnesium salts when exposed to both psoriatic and healthy skin cells provided an important anti-proliferative effect (iv). Yet another study showed that the effects of mineral baths from the Dead Sea had lasting effects for upwards of a month after treatment. (v) Head to Head Comparison (vi) (vii)
Utah’s Inland Sea Composition Dead Sea Composition By: Dr. Chris Meletis N. D.
References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=959) Endnotes
Date:
July 25, 2005 10:37 PM
Endnotes
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=680) Conclusion
Date:
July 25, 2005 10:33 PM
Conclusion Natural progesterone in cream or other transdermal forms appears to be one of the most effective and safe supplements for the treatment of various hormonally related disorders. It may well be superior to estrogen replacement therapy in some cases and should be utilized and evaluated for its superior therapeutic actions. No longer the “forgotten hormone,” natural progesterone, especially in the form of wild yam extract, is nothing less than remarkable in its physiological actions. While so many women are turning to synthetic hormones, tranquilizers, and analgesics to manage PMS and postmenopausal miseries, natural progesterone may well be the best and safest alternative. Getting the word out while scientific studies continue to support the credibility of using natural progesterone is currently underway. It would be nothing less than tragic if an affordable and safe substance like wild yam extract remained unused due to a lack of knowledge. The word is spreading rapidly. Dr. Lee put it well when he stated: I must conclude with a tribute to what I call the women’s underground communication network, the vast informal woman-to-woman communication network that spreads hormone and health information with astonishing speed and extent around the world. An informational and health revolution is underway, thanks to the networking of intelligent, concerned women.33 I consider myself most fortunate to have become acquainted with natural progesterone synthesized from wild yam. For me, the discovery of this safe and marvelous supplement has been nothing less than extraordinary. It has made what was once a life lived at the mercy of the hormonal upheavals into one that is much more even-keeled, healthier and full of optimism.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=679) HELP FOR FIBROMYALGIA?
Date:
July 25, 2005 10:24 PM
HELP FOR FIBROMYALGIA? While scientific documentation on the link between natural progesterone therapy and fibromyalgia has yet to be researched, a significant number of women are finding that the pain associated with this disorder is alleviated when taking transdermal progesterone. The cause of fibromyalgia remains a mystery to medical doctors, although its connection to hormonal factors or neurochemistry has been proposed. Taking natural progesterone has resulted in alleviating insomnia in some women, which may also be beneficial for those with fibromyalgia. The pain of fibromyalgia is especially troublesome at night.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=675) PROGESTERONE AND OSTEOPOROSIS
Date:
July 25, 2005 10:18 PM
PROGESTERONE AND OSTEOPOROSIS At this writing, evidence points to the fact that natural progesterone may be even more effective in treating osteoporosis than estrogen replacement therapy. While this evidence is still in its initial stages, it is significant and must be considered. In 1981, Dr. John Lee conducted a landmark study evaluating the effectiveness of using natural progesterone for osteoporosis.20 His study indicated that it is the cessation of progesterone production in postmenopausal women which causes the development of osteoporosis. Contrary to current trends, progesterone replacement, not estrogen, in fact may be the answer to preventing and treating osteoporosis. Dr. Lee’s study has profound implications for all women. In his practice, Dr. Lee applied a natural progesterone cream on one hundred postmenopausal women and eliminated their usual dose of oral Provera (a synthetic progestin). The majority of these women were in varying stages of osteoporosis. Each participant used the natural progesterone cream for several consecutive days each month over a period of three years. The results were dramatic, to say the least. In addition to preventing further height loss and eliminating aches and pains, the bone mineral density of the spine was preserved in 63 of the women. In other words, these women not only stopped the bone loss associated with osteoporosis but actually experienced an increase in bone mass which, in many cases was more dramatic than had been seen with other therapies. In addition, the incidence of bone fractures actually dropped to zero. Dr Lee’s study found that estrogen was not the panacea for bone density previously assumed. He discovered that the women who took estrogen in combination with the progesterone were not better off than those who took progesterone alone. What was even more impressive was discovering that osteoporosis is a reversible condition with progesterone therapy. Concerning the use of progesterone for osteoporosis, Dr. Lee writes: . . . when my 40 year old housewives had become 60-year olds with osteoporosis and I learned of transdermal natural progesterone (being sold as a skin moisturizer), I started adding it to my therapeutic regimen for osteoporosis, at first only to those for whom estrogen was contraindicated. To my surprise, serial bone mineral density tests showed a significant rise without a hint of side effects. With this obvious success, my use of natural progesterone spread to osteoporosis patients who were not doing all that well on estrogen alone. Again, it proved successful.21 Apparently, women who had the lowest bone densities experienced the greatest increases, implying that age and the progression of the diseases does not affect the beneficial therapeutic action of natural progesterone. This study is profoundly significant in that it strongly suggests that women who take estrogen to prevent or treat osteoporosis may be better off using natural progesterone. As a result of Lee’s findings, several physicians began to use natural progesterone cream for their pre- and postmenopausal patients. The most striking implication of Dr. Lee’s work with natural progesterone is that contrary to current medical opinion, osteoporosis may be more a manifestation of a progesterone deficiency than a lack of estrogen. In addition, the disease may be initiated long before menopause when estrogen levels are still high.22 Moreover, continued estrogen therapy for women with osteoporosis often caps out whereas progesterone therapy continually promotes the production of new bone.23 Dr. C. Norman Shealy, M.D. states: I believe that natural progesterone cream derived from wild yam extract should be used by almost every mature adult . . . The most common cause of death in elderly women is from the complications of fracture of the hip from osteoporosis. Such fractures are also remarkably common in men. I believe that progesterone cream could do more to preserve health and well-being in elderly people than all the drugs in the world.24
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=672) WHY DO SO MANYWOMEN SUFFER FROM HORMONE IMBALANCES?
Date:
July 25, 2005 10:06 PM
WHY DO SO MANYWOMEN SUFFER FROM HORMONE IMBALANCES? The question of why so many women, young and old, suffer from a hormonal imbalance persists. Today’s environment and life style are certainly significant causal factors and explain, to a great degree why even young, seemingly healthy women may experience a lack of progesterone. Dr. Peter Elliston of the Harvard Anthropology Department found through one of his studies of 18 women who all had regular menstrual cycles that seven of them did not experience a mid cycle increase in progesterone levels, suggesting that ovulation did not actually occur.12 Dr. Lee cites this as yet another example of the widespread incidence of anovulatory cycles occurring in young women throughout this country, a fact which is undoubtedly linked to rising infertility rates in the United States. Eating disorders, poor nutrition, widespread use of birth control pills, stress, pollution, etc., contribute to hormonally-related disorders and most certainly affect progesterone production, the ability to conceive and menopausal transitions. CAUSES OF HORMONE IMBALANCES
Dr. Lee believes that widespread use of the birth control pill has caused the ovaries to be compromised, possibly playing a role in the development of PMS that would normally not exist.13 Documented results from using natural progesterone have been impressive but remain relatively unknown by the majority of women. Progesterone therapy can help relieve the following PMS symptoms: breast engorgement, breast tenderness, irritability, headaches, depression, moodiness, fatigue, anxiety, bloating, water retention, cramps, and irregular periods. Dr. Joel T. Hargrove of Vanderbilt University Medical Center has had some very impressive results using natural progesterone to treat his patients with PMS. He has had a 90 percent success rate using this form of progesterone.14 Interestingly, he used oral progesterone which had to be administered in a much heavier dose to achieve the same results Dr. Lee obtained with transdermal progesterone.15
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=665) WHY TOPICAL APPLICATION OF NATURAL PROGESTERONE?
Date:
July 25, 2005 10:00 PM
WHY TOPICAL APPLICATION OF NATURAL PROGESTERONE? Progesterone is a fat soluble compound which maintains its integrity much more readily when absorbed transdermally (through the skin) than when taken my mouth. When progesterone is ingested orally, it is subject to rapid breakdown (metabolism) in the liver, making it considerably less effective. Medical practitioners have used synthetic progesterone in a variety of forms ranging from capsules to injections to vaginal and rectal suppositories. Originally, orally administered progesterone or progestins were not efficiently absorbed through the intestinal wall and had to pass through liver tissue before entering the bloodstream. Consequently, much of the absorbed progestins were metabolized by the liver into inactive compounds. Up to 80 percent of the effectiveness of progesterone can be lost when taken orally.6 By contrast, progesterone is very nicely absorbed transdermally (through the skin) and much more of its biochemical activity is retained. I believe that natural progesterone cream derived from wild yam extract should be used by almost every mature adult . . . I believe that progesterone cream could do more to preserve health and well-being in elderly people than all the drugs in the world.7 Dr. Lee reiterates that “. . . natural progesterone is efficiently absorbed transdermally, a fact that enhances patient’s acceptance of its use and greatly reduces the cost of therapy.”8 Salivary hormonal lab tests are becoming more common and have further supported the effectiveness of natural progesterone absorption through the skin by monitoring levels.9 These tests have proven that progesterone levels rise when wild yam extracts are applied to the skin.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=663) OTHER BIOLOGIC BENEFITS OF NATURAL PROGESTERONE 
Date:
July 25, 2005 09:58 PM
OTHER BIOLOGIC BENEFITS OF NATURAL PROGESTERONE While natural progesterone has been referred to as a progestin because it maintains the lining of the uterus, it is technically separate and totally different from synthetic progestins. In addition, natural progesterone provides a number of biological actions which progestins do not. Some additional benefits reported with the use of natural progesterone include:
THERAPEUTIC APPLICATIONS OF NATURAL PROGESTERONE
Note: Using natural progesterone in cream, oil or other transdermal form is also very hydrating to the skin.
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