Search Term: " ajoene "
Must know health benefits of garlic
Date:
January 23, 2014 09:35 AM
Garlic Garlic is a spice that can be used with virtually all kinds of foods. It is considered as one of the healthiest herbs today. This is because it not only helps in fighting infections but also provides the body with some important nutritional supplements. Benefits of Garlic There are quite a number of compound that can be obtained from it. Allinin found in garlic is easily acted upon by the allinase enzyme when garlic is crushed to give allicin. This compound is known to help in fighting various bacterial and fungal infections in the body. This is mainly due to its sulphur content. Moreover, it is essential in managing the blood pressure as well as improving circulation of blood in the body. ajoene which is a derivative of allicin also plays a vital role in keeping the body healthy. It is well known for its ability to reduce the amount of cholesterol in the body. Additionally, this compound is vital in prevention of blood clots within vessels which could have been fatal. Over the years, many people have resorted to using home remedies in treating common cold and flus. Garlic is one of such remedies. The allicin found in it plays an important role in fighting all kinds of colds. For it to be effective, it is advisable that raw garlic is used. All you have to do is add the crushed garlic to a glass of water or juice and give it a few minutes to settle before taking it. You stand to gain even more from this if you are able to chew the pieces a little bit before swallowing to ensure that most of the allicin is released. Given all the benefits that can be obtained from this herb, its consumption is highly recommended. Those who may not be able to eat it raw can use it as an additive to food so that they can also enjoy its numerous benefits.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2980) Garlic
Date:
September 01, 2008 01:04 PM
Garlic is a member of the lily family, related to onions and chives, and offers many health benefits other than deterring vampires. There is now ample scientific evidence and proof of its beneficial effect on both a healthy immune system and the circulatory system. The active ingredients in garlic are thiosulfinates, of which the predominant one is allicin, sulfoxides such as alliin and dithiins, of which ajoene is the most widely researched. These compounds are not only responsible for the pungent odor of garlic, but also for its benefits to your health. Among the other components of garlic are selenium, manganese and vitamins B6 and C. Before considering the other effects of garlic on your health, we shall first consider how it benefits the immune system. The immune system is an essential part of human biology, and protects your body from invasion by pathogenic organisms. Without the immune system your body would rapidly be overcome by bacteria, viruses, fungi, parasites and other foreign bodies, and your body would rapidly fail to function. The immune system consists of several components that can act in concert to protect you from these foreign invaders. It is too large a subject to be discusses in this article, although its major components are the thymus, the spleen, the lymphatic system, bone marrow, antibodies, and white blood cells of various types. Without it your body would rapidly be broken down to nothing, and would revert to a skeleton in a few weeks. It is your immune system that causes inflammation, fevers, boils and pus. These are all examples of the immune system at work to protect your body, and even a fever is the immune system raising your body temperature to one that is unfavorable to invaders. Arthritis and hay fever are other examples of how your immune system reacts to invaders, in one case mistaking damaged joint tissue as being foreign and responding by causing inflammation to protect the joint, and in the other a reaction to invading bodies such as pollen. So what does garlic do to help your immune system? Let's first have a look at the inflammatory reaction of the immune system, a prime example of which is rheumatoid arthritis. The inflammation is caused by compounds known as prostaglandins and thromboxanes, the biosynthesis in your body of which requires the enzymes lipoxygenase and cyclooxygenase (LOX and COX). If these enzymes can be inhibited, then the inflammatory response can be modulated, and LOX and COX inhibition is one of the studies currently being carried out into the treatment of some forms of cancers. However, where garlic comes in here is that two effective non-reversible inhibitors of LOX and COX are the chemicals Di(1-propenyl) sulfide and ajoene, and both of these are components of garlic. Garlic can therefore be used, not to stop the inflammatory response altogether since it is an essential part of the immune system for certain infections, but to modulate it and protect you from the more severe effects of conditions such as arthritis - both osteo and rheumatoid - and asthma, which is also an immune response. Allicin has been shown to work with vitamin C to kill certain types of bacteria and viruses, and can help the immune system to protect you from colds and flu, Candida and some gastroenteric viruses. It can also be effective against some of the more powerful pathogens such as tuberculosis. It should be stressed that garlic will not cure these conditions, but help the immune system to deal with them. In fact with respect to the common cold, a study at Munich University has shown that garlic significantly reduces the activity of kappa-B, which is a nuclear transcription factor that mediates the inflammatory response. In other words, the cold symptoms are greatly reduced. This is significant, since increased kappa-B levels can be triggered off by any pathogen that causes an inflammatory response by the immune system (e.g. infection, allergens, physical trauma). The study showed that unfertilized garlic provided a reduction of 25% in kappa-B activity, while garlic fertilized with sulfur reduced it by 41%. There have been other studies carried out that demonstrated that Helicobacter pylori, the organism responsible for gastritis and peptic ulcers, was less active in those that took a regular amount of garlic in their diet. This was shown by measuring the antibody concentration, and while H.pylori was found in both sets (with and without garlic in the diet), the antibody count in the garlic-eating set was much lower indicating a significantly lower population of the bacterium. Another unexpected result was that a group taking both cooked and uncooked garlic had a lower antibody count than those taking either cooked or uncooked. This appears to indicate that cooking changes the chemical nature of garlic, so that both forms work together to provide a more potent effect that cooked and uncooked separately. What has also been established is that odorless garlic has less of an effect on the immune system that natural garlic, so while the odorless type is more socially acceptable, it is not so good at supporting your immune system. The allicin levels in odorless garlic are very much lower than in the natural bulb. Garlic has also been found to be able to help with certain types of cancer. Two servings weekly have been found effective in protecting from colon cancer. Allicin has been found to protect colon cells from the toxic effect of various chemicals, and also reduce the growth rate of any cancerous cells that develop. People in Southern Europe consuming large quantities of garlic have been shown to be 39% less liable to contract cancer of the mouth and pharynx, and 57% less liable to contract cancer of the esophagus. It also had an effect on other cancers, including breast and ovarian cancer. However, the effect of onions on such cancers is even greater. Most people are aware of the cardiovascular benefits of garlic, and it can reduce blood pressure, cholesterol levels and serum triglyceride levels, thus protecting against the harmful condition of atherosclerosis and also of diabetic heart disease. Reduced atherosclerosis means a reduced chance of heart attacks or strokes. It also appears to possess antioxidant properties.
There is no doubt that garlic helps to promote a healthy immune system, although the odorless form appear to be less effective in this respect as natural garlic, and there is evidence that a diet containing uncooked and cooked garlic can be more effective than either of these alone.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1879) GARLIC AS A NATURAL BLOOD THINNER
Date:
June 25, 2005 10:03 AM
GARLIC AS A NATURAL BLOOD THINNER Blood clots pose a significant threat to one’s health and longevity and substantially raise the risk of heart attack or stroke. Blood clots consist of platelets and fibrin. The amount of fibrin in the body is believed to be significantly related to heart attack or stroke risk. In fact, new medical tests are currently being developed to test more carefully for fibrinogen levels in the blood as a predictor for heart attacks and stroke. The chemical constituents of garlic can actually reduce fibrin formation and help to decrease fibrin that already exists in the blood. Some researchers have even gone as far as to state that Garlic is more effective at preventing blood clots than aspirin therapy.17 ajoene, a sulfur compound contained in garlic seems to be responsible for its anti-clotting effect. Because ajoene is only viable at room temperature or above, it is not present in raw or freeze-dried garlic. It is believed that adding garlic to the diet can help to increase the breakdown of fibrin from 24 to 130 percent in people who have cardiovascular disease.18 Researchers reported at the First World Congress on garlic that ajoene is such a powerful anti-clotting agent that may prove valuable in cardiac surgeries, including balloon angioplasty, in which blood vessels are artificially dilated to facilitate better blood flow.19 Europeans routinely used garlic as a natural blood thinner which has none of the side-effects associated with synthetic drugs. It should be noted, however, that anyone who suffers form a hemorrhagic disorder (bleeding) should not take commercial garlic products which contain significant amounts of ajoene.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=432) HIGH BLOOD PRESSURE AND GARLIC THERAPY
Date:
June 25, 2005 10:01 AM
HIGH BLOOD PRESSURE AND GARLIC THERAPY Garlic has been used for generations in China and Japan for as a traditional medicine for hypertension. Even today, it continues to be a popular remedy for a disease that has become an epidemic in the western world. Taking a daily dose of garlic can result in a 12 to 30 mmHg reduction is systolic blood pressure and a 7 to 20 mmHg reduction in diastolic pressure in people who suffer from essential hypertension.12 One scientific study revealed that 40 out of 100 patients with high blood pressure experienced a reduction of 20 mmHg or more after a week of garlic treatment.13 Apparently, rabbits and humans who have been tested with garlic have demonstrated a rapid and continued decrease in blood pressure. One reason for this is that garlic seems to dilate blood vessel walls.14 It is the methyl allyl trisulfide contained in garlic which creates this action. Evidently, the effectiveness of using garlic for high blood pressure is dependent to some extent on the type of garlic used. Bulgarian studies suggested that aged Garlic extracts were more effective although this view has been subject to debate. Most practitioners who use garlic for their hypertensive patients recommended a high dosages initially. In 1992, an article in Planta Medica, a German scientific journal, suggested that gamma-glutamyl-S-allyl-cysteine, a peptide found in Garlic, inhibits a certain enzyme which is involved in the conversion of certain hormones that actually regulate blood pressure. Angiotensin I does not raise blood pressure, however, Angiotensin II can. The peptide found in garlic inhibited the enzyme that changes Angiotensin I into Angiotensin II.15 Consequently, blood pressure levels dropped. In addition to the actions discussed above, the ajoene compounds in garlic also help to prevent high blood pressure by inhibiting the tendency of blood cells to adhere together and create clots. Garlic oil can increase the breakdown of fibrin by over 100 percent in humans.16 When the blood is discouraged from clotting, blood flow is not restricted, therefore, blood pressure does not rise. Some people who have been on hypertensive drugs have gradually been able to wean themselves off using garlic. If you decide to use garlic for high blood pressure, make sure you check with your doctor and do not abruptly stop taking your medication. (Note: People who have abnormally low blood pressure need not avoid eating garlic. There is evidence to suggest that hypotension benefits from the therapeutic effects of garlic as well as hypertension. Considering these findings, it would seem that garlic acts to normalize blood pressure whether it be high or low, an action which prescription drugs cannot accomplish.)
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=431) GARLIC (allium sativum)
Date:
June 25, 2005 09:54 AM
GARLIC (allium sativum) Common Names: Stinking Rose, Poor Man’s Treacle Plant Parts: bulb Active Compounds: Garlic contains more than 200 chemical compounds. Some of its more important ones include: volatile oil with sulphur-containing compounds: (allicin, alliin, and ajoene), and enzymes: (allinase, peroxidase and myrosinase). Allicin is what gives garlic its antibiotic properties and is responsible for its strong odor. ajoene contributes to the anticoagulant action of garlic. Garlic also contains citral, geraniol, linalool, Aphellandrene and B phellandrene. The allyl contained in garlic is also found in several members of the onion family and is considered a very valuable therapeutic compound. Pharmacology: The allicins contained in garlic have a fibrinolytic activity which reduces platelet aggregation by inhibiting prostaglandin E2. Allivium sativum has also exerted some effect on glucose tolerance for both hypo-and hyperglycemia by reducing insulin require-ments to control blood sugar. The compounds contained in garlic have also demonstrated their ability to lower total serum cholesterol and triglyceride levels while elevating HDL levels. LDL synthesis is suppressed by garlic. Garlic allicins have also acted as a larvacide and bacteriostat, active against gram-positive or gram-negative microorganisms. In addition, the compounds can destroy certain fungi such as Candida albicans. Several other microbes are effected by garlic, including some viruses. Most researchers agree that the sulfur containing compounds of garlic, especially allicin, alliin, cy-croalliin, and dialllyldisulphide are the most biochemically active. In addition, certain unidentified substances of garlic will probably emerge as other therapeutic agents. (Note: Before a bulb of garlic is crushed or chopped, it contains relatively few medically active compounds. Once it is cut, however, chemical reactions take place which create dozens of new compounds.) Vitamin and Mineral Content: B-vitamins especially B-1, vitamin C, vitamin A, flavonoids, ascorbic acid, phosphorous, potassium, sulphur, selenium, calcium, magnesium, germanium, sodium, iron, manganese and trace iodine. Seventeen amino acids are found in garlic, including eight essential ones. Character: antibiotic, antihistamine, anticoagulant, expectorant, antibacterial, antiparasitic, alterative, diaphoretic, diuretic , expectorant, stimulant, antispasmodic, promotes sweating, lowers blood sugar and blood cholesterol levels, lowers blood pressure Body Systems Targeted: respiratory, cardiovascular, digestive, and nervous systems
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=425) Garlic for the Ages - eat garlic because it's good for your heart...
Date:
June 13, 2005 09:58 AM
Garlic for the Ages by Phyllis D. Light, RH Energy Times, January 1 , 2004 If you eat garlic because it's good for your heart, you swallow a plant renowned through human history: Garlic was eaten by Roman soldiers for courage; Egyptian slaves ate it to build strength; Christians, Moslems and Hindus include it in their sacred books. Others have used it as an aphrodisiac, a vampire deterrent and a magical charm. Garlic has a long history as a culinary and medicinal herb that people either love or hate. Its pungent aroma and warming flavor captivates or repels, but its wealth of natural chemicals does great things for your heart. Garlic (Allium sativum), a member of the onion family, is native to Siberia but, in modern times, has become a treasured naturalized citizen grown all over the world. Garlic's use in folk medicine dates back about 7,000 years, making it one of the oldest known medicinal foods or herbs. In modern times, garlic is generally used as a condiment lending a unique, pungent flavor to dishes, but in medieval times, garlic was cooked and eaten as a vegetable in its own right. Today you can revel in a wealth of garlic choices, consuming garlic raw, cooked in various recipes, as a dried concentrated powder, as a fresh liquid extract or as aged garlic powder. Powerhouse Herb Each little clove of garlic is a powerhouse of good-for-you natural compounds, vitamins and minerals. The biologically active constituents of garlic include allyl sulfur compounds as well as the minerals germanium and selenium. When you chop up raw garlic and allowed it to stand for about 10 minutes or more, the herb's fragments release an enzyme that converts its compounds from allyl sulfur to another natural chemical called allicin. Although some allicin is found in garlic before it is cut apart, the yield multiplies considerably when the garlic clove is chopped or pressed and exposed to water (Garlic Conference, Newport Beach, 11/15/98; Penn State). Many researchers believe that the more allicin produced, the better the health benefits. (Although this is still being debated among the garlic cognoscenti.) But garlic's benefits don't end meekly on the kitchen counter with its allicin content rising. Cooked garlic and aged garlic contain other helpful chemicals called diallyl sulphides. Consequently, in any form, garlic produces beneficial health effects. Fortunately, since raw garlic juice or oil can often irritate the stomach lining, especially in people with sensitive stomachs and delicate digestive systems, garlic supplements and cooked garlic are both helpful for heart health. Aged Garlic Extract Aging garlic significantly reduces its irritating compounds and makes it easier on the stomach. In the aged form, all of garlic's healthy sulfur-containing compounds are converted to water- soluble compounds that retain garlic's natural health benefits. In addition, the pungent odor of the garlic is greatly reduced, an outcome many people desire. When a group of researchers at Brown University studied the effects of aged garlic extract on people's cholesterol levels, they found that after six months, cholesterol dropped about 6% (Am J Clin Nutr 1996; 64:866-70). In another study from Brown, researchers found that aged garlic extract reduced platelet adhesion, a sticky blood problem that can cause vessel blockages (New Drug Clin 45(3):456-66). When platelets are less sticky, they are less likely to form blood clots that can cause heart attacks. Garlic and Heart Disease A growing body of research shows that a clove of garlic a day can significantly reduce your risk of heart disease. A four-year study of 280 people who took dried garlic powder three times a day found a striking reduction in the types of arterial plaque blockages that threaten the blood supply to your heart. Interestingly, in this particular study, women displayed a greater reduction in plaque than men (Atherosclerosis 2000; 150:437-8). Another study found that garlic may also keep important blood vessels more supple and less likely to spasm. Arterial spasms have been linked to heart attacks and other cardiovascular problems in women. Aortic Complications As you age, the aorta, one of the main arteries that carries blood, may harden, reducing blood flow from the heart and placing damaging stress on a number of other bodily organs. In research at Ohio State University, people who took garlic supplements had 15% less aortic stiffness than people who avoided garlic (Circulation). In this study, scientists found that the older people enjoyed the greatest cardiovascular benefits from daily garlic use. Researchers believe this extra benefit is linked to the fact that as you age, the endothelial tissue in the linings of the aorta and other blood vessels become less responsive to the need to dilate (expand). As a result, when more blood flow is required, and the heart pumps faster, these vessels take more of a beating from the friction of blood passing through them. That restriction in dilation has two damaging consequences: In one instance, vessel walls can be injured. In response to these injuries, cholesterol collects on artery walls, plaque forms and the blood supply to the heart muscle can be restricted, leading to a heart attack. In other cases, arteries can restrict blood flow to the heart simply because of the inability to expand sufficiently. The Ohio State researchers found that arteries in folks aged 70 to 80 benefited the most from taking garlic. But those in their 60s also benefited significantly. Garlic's natural antioxidant properties can also help protect the heart from damage after surgery (BMC Pharmacology 9/02). In a study performed on lab animals, researchers found that oxidative stress, a source of cell damage that takes place after surgery, dropped when the animals ate a diet that included garlic. Oxidative stress can seriously reduce cardiac function, limit the amount of blood the heart can pump and cause permanent damage to the heart muscle. Garlic Against Blood Clots Under normal circumstances, blood clots serve a useful purpose: Cut yourself and a blood clot stops the bleeding. Without this clotting ability, you might bleed to death. But if your blood is too prone to clotting, these clumps can cut off blood supply to your heart and other organs, endangering your life. In a study of apparently healthy individuals whose relatives had already suffered from heart disease, researchers found that their blood formed thick, tangled blood clots, increasing their risk of heart problems (Circulation rapid access 9/23/02). These blood clots are made of a substance called fibrin, a protein in the plasma that can form elastic threads that cut off blood flow. While these researchers recommended aspirin as an anti-clotting measure for people at risk of heart disease, garlic can also help break up fibrin and possibly lower your chance of heart problems (Pharmatherapy 5(2): 83). The fibrin that forms clots is produced by blood cells called platelets. Other scientists who have looked into garlic's benefits believe that one of its natural chemicals called ajoene may keep platelets from producing excessive fibrin and gumming up the flow of blood through arteries. If you've rarely indulged in garlic, you may need a period of adjustment in growing accustomed to its unique taste and aroma. But its heart benefits confirm the long-ago observation by Pliny, an ancient Roman naturalist, that "garlic has powerful properties."
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