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Search Term: " wiring "
Health Check: what makes it so hard to quit drugs?   
Date:
December 17, 2016 10:59 AM
The brain becomes primed to repeat drug taking over and over without actually thinking about it. When the dopamine system is damaged in that part of the brain, it makes it much harder to think through consequences and make considered decisions, so drug use becomes more automated. The wiring of the dopamine reward system makes it compelling to use drugs, and the damage to the system makes self-regulation more difficult. The brain and body adapt over time to taking drugs and react when the alcohol or other drugs leave the system. Key Takeaways:
"Every drug affects different neurotransmitter pathways in different ways. Some affect more than one neurotransmitter. But most drugs impact the dopamine system in some way." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3662) Use Curamin For Painful inflammation and see how your life can change! 
Date:
June 15, 2010 05:10 PM
Pain is a warning signal that something has gone wrong in the body or that something is damaged. Pain is so unpleasant that it motivates you to remove yourself from the cause of this damage as quickly and completely as possible. There are four ways to relieve occasional pain: 1. You can leave the pain alone, but flood the body with feel-good substances that push the pain signals out from your consciousness (drugs). 2. you can put the person asleep and do surgical procedures to cut nerves and stop the pain. 3. You can impact the nervous system the internal wiring that carry the pain signals to dull them so that the signal becomes less distinct and weaker. 4. You can target what is causing the pain in the first place (most recommended). Occasional pain can be perfectly normal for instance, starting a new exercise routine when you are a bit out of shape. When dealing with type of pain, helping the body to balance its inflammation response can have tremendous impact.
This is where curamin is the answer to pain problems. They all break down as follows: DLPA: DL-phenylalanine is an amino acid consisting of equal parts D-phenylalanine and L-Phenylalanine. D- inhibits the breakdown or compounds called enkephalins. Enkephalins are associated with positive mood and have been shown to relieve occasional muscle pain due to exercise or overuse. L- is converted into tyrosine, which in turn is used to produce brain chemicals norepinephrine and dopamine.
Boswellia: Clinically tested boswellia helps reduce the activity of the inflammatory enzyme, 5-LOX (lipoxygenase). A compound (beta boswellic acid) found in boswellia which interferes with its benefitical activity has been removed, greatly increasing the effectiveness of this extract. Nattokinase: the enzyme nattokinase helps promote blood flow, aiding the other ingredients in the formula to reach all areas of the body. So if you are suffering from chronic pain, give curamin a try and see how well you can feel. If you are concerned about its effectiveness, have no fear, VitaNet ®, LLC offers a 100% Money back guarantee if the product does not work for you.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2167) Inosine
Date:
December 19, 2008 12:35 PM
Inosine is a specific type of glycosylamine that consists of a base bound to a deoxyribose or ribose sugar. This type of glycosylamine is referred to as a nucleoside, others being adenosine, thymidine and cytidine. It is available naturally in brewer’s yeast and major organ offal such as liver and kidney. It’s function in animal biochemistry is in the production of ATP (adenosine triphosphate), often known as the molecule of energy, that is essential for the generation of energy by the mitochondria in our body cells. It’s biochemistry is described below. Inosine is synthesized as inosine monophosphate by means of a complex series of biochemical reactions. The inosine monophosphate is a precursor for adenine, a nucleotide and purine base that reacts with ribose to form adenosine. This is another nucleoside that can be phosphorylated to produce adenosine monophosphate (AMP), the diphosphate (ADP), the triphosphate (ATP) and cyclic adenosine monophosphate (cAMP). Each of these is involved in the metabolism of energy in the mitochondria. Glucose undergoes a number of enzyme-catalyzed reactions in the presence of oxygen that ultimately breaks it down to water and carbon dioxide, plus at least 36 molecules of ATP via glycolysis and then the Krebs cycle. The ATP reacts with water to release energy and form ADP. The ADP can then be phosphorylated to produce more ATP. The starting point of all of this is inosine, and it is little wonder this nucleoside is used by athletes to help boost their energy. Not only that, however, but adenine is also the precursor of amino and nucleic acids responsible for the generation of RNA and DNA, and it is also responsible for the production of many coenzymes. These provide other opportunities for its use elsewhere in medicine, and it has also been found to possess other medical properties that will be discussed later. It was in the 1970s that inosine was first used to boost athletic performance due to its part in the generation of the energy needed by every muscle in the body. Its use began in eastern countries, although evidence at the time did not support the theory. Nevertheless, this did not deter its advocates, and inosine continued to be used by athletes, a practice that has now spread world-wide. It has been found to be a metabolic activator, in that it supports metabolism through the generation of energy. Inosine has been used by power lifters for heavy weight training to increase the capacity of the blood to carry oxygen, and strength athletes, particularly of the Eastern Bloc, used it from the mid 1970s onwards. Inosine appears to increase the natural ability of the body to handle strenuous workouts, although there is no scientific proof of this. However, those that use it claim an increased ability to carry out intensive training workouts and an improvement in their competitive performance. The nucleotide can penetrate the cell walls and get to where it is needed to take part in the metabolism of energy through the production of ATP. Now, however, inosine has an entirley different application in medicine. Studies have shown that it could support those suffering from MS (multiple sclerosis) and strokes through its pereceived neuroprotective properties. It appears to promote axonal rewiring, where undamaged neurons appear to grow new connections with damaged areas of the brain, and undamaged neurons seem to branch out to replace some of the damaged neurons. Inosine is also an intermediate in the production of uric acid through purine and purine nucleoside degradation. Uric acid is a powerful antioxidant, particularly in respect of peroxynitrite, a nucleophile that causes the type of axonal degradation that is associated with multiple sclerosis. It thefore helps in two ways: through the production of uric acid, and in promoting axonal rewiring that can improve brain function in patients. Another potential medical use for the substance is based upon the discovery that inosine and related compounds can act as powerful anti-inflammatories through their effect on inflammatory macrophage proteins. Certain conditions can cause the release of these macrohages, and where it is an undesirable side-effect, inosine can be administered to prevent it occuring. Inosine appears to inhibit the production of pro-inflammatory cytokines without inhibiting anti-inflammatory cytokines. It appears to do so extracellularly, although the effect can be reversed by the blockading of adenosine receptors. However, it is a convenient way of avoiding this sometimes serious condition, which is a natural function of the immune system, without affecting any other part of that system’s essential work. It is not an essential nutrient, since it is synthesized biochemically, but a supplement of inosine is certainly worth taking if you want to increase your ability to carry out athetic exercise requiring a high energy output and increased blood oxygen availability. It also helps to reduce recovery time, and proponents of its use claim that it enables you to exercise at a higher level for longer. Although the medical evidence for this is scant, not a lot of work has been done in trying to establish it, and those that use inosine in this way swear that it is effective. The theory certainly indicates that it should be effective in helping to produce more energy, and also that it should be able to make more oxygen available, and some athletes have been taking it for decades with excellent results. There are no known side effects of its use, although pregnant women and nursing mothers are recommended not to use it, as with many other health supplements the pathology of which have not been closely studuied. As with any supplement, you are highly recommended to consult your own doctor or physician when taking any supplement, particular if you have a current medical condition or are taking prescriptive medicines. If you are predisposed to gout, and some people are, the uric acid it produces can render inosine unsuitable. Uric acid reacts with calcium to produce the sodium urate that is deposited on the cartilage and tendons of the joints, particularly the big toe. It is a very painful condition, so those that have suffered gout in the past should not take inosine as a supplement.
Otherwise, its effect on your athletic performance might be academic!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1951) Pregnant and eating for two...
Date:
October 21, 2005 01:36 PM
Not - Quite - Dual - Nutrition It’s time to ditch a dietary cliché often foisted on expectant moms. “try to keep in mind that you are not eating for two, you are carefully eating for one,” write Catherine Jones and prenatal nutrition expert Rose Ann Hudson in Eating for Pregnancy (Marlowe & Company), who add that pregnancy “is not a time to skip meal, eat junk food or lad up on empty calories for quick energy.” The idea is to eat a nutritious diet that allows you to gain weight gradually as your baby grows. It helps to be at a healthy weight when starting a family. Being overweight makes conception more difficult, and at least one study ahs found a link between excess maternal weight and the risk of a birth defect called cleft palate (in which the roof of the mouth is split from behind the teeth to the nasal cavity). However, dieting during pregnancy may actually program a child for obesity by rewiring the developing brain, so try to lose weight before you try to conceive. How much should you expect to gain over the course of nine months? “A lot depends on your unique circumstances and the advice of your health care provider, but in general you can anticipate adding from two to five pounds a month for the first 14 weeks and roughly a pound a week thereafter until your due date-between 25 and 35 pounds in total. That translates into roughly and extra 300 calories a day; Jones and Hudson say that more nourishment may be necessary if you are breastfeeding, extremely active or carrying more than one child. Since stress and anxiety often lead to out-of-control eating (and gaining), be sure to tend to your own emotional needs during what can be a very exhilarating, yet sometimes overwhelming, time of life. For maximum nutrition try to eat a variety of foods while avoiding anything that provokes morning sickness. Whole grains provide both steady energy (unlike sugar-fueled spikes and crashes) and B vitamins to boot. Do not scrimp on fat-your baby’s developing nervous system depends on it-but “don’t use your pregnancy as an excuse to pig out, either,” warn Jones and Hudson. Stick with such unsaturated fats as olive oil along with rich sources of omega-3 fatty acids like flax seed oil. You definitely want to indulge in those omega-3s, which appear to boost infant intellectual development. Fish is a fine source of both omega-3 and the high-quality protein needed to build your baby’s tissues, but beware: Some species such as fresh tuna, swordfish, tilefish and king mackerel, can be contaminated with mercury. Your best low-mercury bets are catfish, pollock, salmon, and shrimp. (Other good protein sources include chicken, cottage cheese, lean red meat, yogurt and milk, all organically sourced whenever possible.) Supplemental fish oil is another omega-3 possibility because “mercury is found in the muscle of fish and not in the oil,” according to OSU’s Jane Higdon, who suggests consulting your health care practitioner for advice. “If I was going to take a fish oil supplement, I’d look for one that the manufacturer is testing for PCBs (an industrial pollutant),” such as products that meet California’s Proposition 65 standards. Don’t forget to stock the fridge with fresh produce. Fruits and veggies are richly endowed with vitamins and minerals; for example, making like Popeye and downing your spinach helps ensure you get plenty of folic acid and iron. These superfoods also supply phytonutrients, substances that may actually help protect your baby against cancer even as they enhance your own well-being. Studies on the link between maternal diet and childhood cancer protection are in the early stages according to Dr. David Williams, a researcher at the Linus Pauling Institute, but he says that shouldn’t stop you from loading up on cancer-fighting green stuff. “Certainly among the vegetables the cruciferous ones (the broccoli family) are particularly valuable in protecting against cancer,” he says. “These vegetables are also a good source of fiber and vitamin C.”
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=862) OBESITY: A 2Oth- Century Plague 
Date:
June 25, 2005 07:46 PM
OBESITY: A 2Oth- Century Plague Overview Our modern, fast-paced, high stress, sedentary lifestyle with over-abundant caloric intake is a prescription for obesity. Obesity is an especially critical problem for black women who have nearly twice the rate of obesity of white
---------------------------------- women.41 Culturally, being overweight is not looked on graciously, even by physicians.42 There has been no end to the torture we have put ourselves through to be or at least look thin. From corssets to stomach stapling and liposuction to wiring our jaws shut, we’ve tried it all. So where are we today? The following are indicators of abundant obesity: Research and public education efforts are in agreement that excessive dietary fat is the primary cause of adult obesity.2, 46, 47 Despite the fact that food manufacturers have flooded the supermarkets with low-fat, artificially sweetened, “lite” products, we are fatter than ever before. Is maintaining a healthy weight really that difficult? In its simplest form gaining or losing weight is a matter of the balance between energy in and energy out. This simplistic approach led to the early starvation diets. Unquestionably, these conventional very-low-calorie diet plans do not work. For most of us the first thing we lose is our sense of humor; then maybe some weight or possibly our self-esteem. The fact is, as most of us have regrettably discovered, that drastically reducing our calorie tally only serves to slow our metabolism and make us even more efficient at the business of storing and hoarding fat. Since very-low-calorie diets didn’t work alone, exercise was added to the regime. This also failed miserably because the first thing the body does when it is in a starvation mode is to burn off muscle mass so as to conserve energy supplies. In fact, in animal studies, semi-starved animals maintained nearly the same fat to muscle ratio as their well-fed litter mates.43,44 Even worse, when food is again available the body not only gains back all the original fat but an additonal few pounds just in case this ever happens again. Is it any wonder then that yoyo dieting leads to obesity and a host of other problems?42,45 The reconstruction of muscle mass after starvation, a much slower process than regaining body fat, leaves a person feeling weak and even more lethargic than before he started his diet.
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Everyone experiences occasional pain at some time in their lives. We use the word pain in our jargon to describe something unpleasant and to indicate the necessity of toughening up such as “no pain no gain”. As common as the word pain may be, there are many misconceptions about pain. Four out of five Americans believe that occasional pain is just natural and unavoidable due largely to getting older. More than one quarter of Americans believe there is absolutely nothing they can do to relieve their personal pain. 
Curamin contains four high potency ingredients that make it work so well. The first ingredient is curcumin from Turmeric. Curcumin is a super antioxidant with a ORAC value of 1592.27 each gram. That’s 24 times stronger than blueberries. Curamin also contains Boswellia, DLPA (DL-phenylalanine) which help fight inflammation and maximize the endorphins and enkiphalins in our own body. It finally contains nattokinase which is a systemic enzyme known to help improve circulation. 
Curcumin: Curcumin, a compound found in the spice of turmeric, inhibits multiple inflammation pathways in the body. It is also a potent antioxidant. Some of the benefits associated with curcumin include immune system modulation, protection from oxidative stress, and support the body’s natural anti-inflammatory response. The specialized extract in this formula has the highest absorption of any curcumin extract available for maximum health benefit. (Found in Curamin) 
