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Lipotropic Complex...helps
support a healthy liver through the proper metabolism of fats*2, 3, 4, 13,
23 Features & Benefits
Facts About Lipotropic ComplexLipotropics
are a class of substances that play important roles in the body’s use
of fat. Many substances have lipotropic properties: choline, inositol and
methionine are among the most noteworthy.*1 Through their involvement in
lipid (fat) metabolism, lipotropics help maintain a healthy liver.*2 Liver Function:The
liver is the largest internal organ. Seated in the upper abdominal cavity,
the liver is involved in several important functions, such as storing
extra glucose (blood sugar) as glycogen, regulating blood levels of amino
acids (protein “building blocks”), and producing important proteins
for blood plasma. The liver also manufactures bile, which is necessary for
the absorption of fat-soluble substances including many vitamins. A
sluggish or congested liver can be caused by diminished bile flow and can
lead to impaired liver function. The
liver is also responsible for detoxifying chemicals and filtering blood.
The liver does this by extracting toxic substances from the bloodstream
and altering their chemical structure so that they become water-soluble.
The toxins can then be excreted from the body. Choline & Inositol:Choline
and inositol are substances known as co-enzymes. They are required for the
proper metabolism of fats, and have the ability to remove fat from the
liver.*3, 4 Choline’s function in fat metabolism is tied to its role in
bile production because bile acts as an emulsifier (allowing water and
lipids to combine) to more readily transport fats. Without choline, fats
can become trapped in the liver, where they can block normal metabolic
functions.*5 Both
of these lipotropes are important building blocks for cell walls (choline
being a key component of phosphatidyl choline, or lecithin).*6 Choline (as
a part of the neurotransmitter acetylcholine) and inositol are necessary
for normal nerve and brain function.*7, 8 The
body can produce choline, with the help of vitamin B12, folic acid and
methionine. Natural choline production however, may not always be adequate
to meet daily needs.*5 Studies show that diets deficient in choline lead
to undesirable changes to liver, kidney and brain functions.*9 There is no
established daily recommended intake for choline, but the average diet
supplies between 500 mg and 1,000 mg of choline daily. The best dietary
sources of choline are eggs, liver and other organ meats, brewer’s
yeast, wheat germ and soybeans. A lack of inositol has been shown to
produce an accumulation of triglycerides in the liver.*10 The average
dietary intake of inositol, which is found in a wide variety of foods, is
1,000 mg daily.*11 Methionine:Methionine,
an essential sulfur-containing amino acid, has lipotropic properties
similar to those of choline.*12 Two other important amino acids, cysteine
and taurine, depend on adequate levels of methionine for their
biosynthesis in the body. Methionine is one of the nutrients required
during the body’s manufacture of choline
and a deficiency of this amino acid will adversely affect fat
metabolism.*13 Ingredient HighlightsHerbs:
The
herb milk thistle (Silybum marianum) contains a group of flavonoids, collectively
referred to as silymarin, which are its active constituents.14,
15, 16 Silymarin
enhances liver function by acting as an antioxidant, which lessens the
presence of free radicals in the liver.*17 In addition, silymarin aids the liver by binding to the outside
of liver cells, inhibiting the entrance of certain toxins which could
otherwise interfere with normal liver function.*18 The
formula also provides other herbs which have been traditionally used to
help support liver function.*19
These are: Beet Root (Beta vulgaris
rubra), Dandelion Root (Taraxacum
officinale), Culvers Root (Leptandra
virginica) and Barberry Root (Berberis
vulgaris). Other Ingredients:
Betaine is both produced by the body and present in foods such as broccoli,
spinach, and sugar beets. Betaine, by increasing levels of a substance
called S-adenosylmethionine (SAM), may reduce fatty infiltration of the
liver.*20 Vitamin
B6 indirectly participates in lipotropic activity because it is involved,
along with folic acid, in the liver’s use of choline and methionine. Lecithin is a rich source of the
lipotropes choline and inositol. L-carnitine, synthesized from amino acids, helps convert fat into energy*21
by facilitating the entry of fatty acids into specialized areas of the
cells called mitochondria. The mitochondria use carnitine to generate
energy.*22 The amino acid taurine is a component of bile that is necessary for fat digestion.*23The
essential mineral chromium is a
component of the glucose tolerance factor (GTF).*24
Chromium assists in the
process that produces fatty acids and may help maintain healthy
cholesterol levels.*24, 25 Nature’s Life
Lipotropic Complex
Nature’s
Life Lipotropic Complex formula provides the full 1,000 mg potency of all
three major lipotropes: choline, inositol, and methionine. References
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