Complete Ingredient Breakdown: What Is Inside SP-16?

Every 2 VegCaps serving of Solaray Prostate Blend SP-16 delivers 1,000 mg of an expertly curated botanical matrix. Here is how each plant extract works inside the body:

1. Saw Palmetto (Serenoa repens) Berry

Saw Palmetto is the cornerstone of male phytotherapy. Its berries are packed with fatty acids and beta-sitosterol, which help block 5-alpha-reductase—the internal enzyme that converts regular testosterone into DHT. By helping normalize DHT stimulation, Saw Palmetto preserves a comfortable prostate size and relieves urinary hesitation.

2. Pumpkin Seed (Cucurbita pepo)

Pumpkin seeds contain delta-7-sterols and bioavailable zinc. Zinc is concentrated in healthy human prostate tissue more than almost any other organ. Studies show pumpkin seed extracts tone the detrusor muscle of the bladder wall, facilitating complete emptying and reducing pressure around the bladder neck.

3. Stinging Nettle (Urtica dioica) Root

While saw palmetto tackles 5-alpha-reductase, stinging nettle root binds to Sex Hormone-Binding Globulin (SHBG). This prevents circulating sex hormones from attaching to prostate membrane receptors, delivering a multi-angled approach when paired with saw palmetto.

4. Cornsilk (Zea mays) Tassels

Cornsilk is a time-tested herbal demulcent rich in natural potassium and flavonoids. It creates a calming, protective coating across the urinary mucosa, soothing irritation in the bladder and burning sensations during urination.

5. Parsley (Petroselinum crispum) Aerial Parts

Parsley acts as a gentle, natural aquaretic. It encourages balanced fluid elimination without disturbing systemic electrolyte levels, helping flush microscopic cellular debris from the urinary tract.

6. Ginger (Zingiber officinale) Root

Ginger root supplies pungent gingerols and shogaols. These bioactive compounds downregulate prostaglandins and inflammatory cyclooxygenase enzymes (COX-2), curbing swelling and localized pelvic discomfort.

7. Burdock (Arctium lappa) Root

Known in classical herbalism as an alterative, burdock root provides prebiotic inulin, arctigenin, and polyphenols that assist lymphatic filtration and natural fluid cleansing throughout the pelvic basin.

8. Kelp (Laminaria spp.) Whole

Supplies ocean-derived organic iodine and essential trace elements that maintain healthy cellular differentiation and whole-body metabolic equilibrium.

Other Ingredients

Vegetable Cellulose Capsule and a Trace Mineral Complex. Free of artificial colors, synthetic binders, and chemical preservatives.

Scientific Evidence & Clinical Citations

The herbs in Solaray Prostate Blend SP-16 are supported by peer-reviewed clinical research investigating lower urinary tract symptoms (LUTS) and prostate cellular health:

1. Stinging Nettle (Urtica dioica) in Benign Prostate Hyperplasia:

In a 6-month randomized, double-blind, placebo-controlled crossover trial with 558 men, 81% of patients receiving Urtica dioica reported significant clinical improvements in urinary symptoms compared to only 16% in the placebo cohort. Maximum urinary flow rate (Qmax) improved by 8.2 mL/s, and post-void residual urine volume was nearly halved (dropped from 73 mL to 36 mL).

Citation: Safarinejad MR. Urtica dioica for treatment of benign prostatic hyperplasia: a prospective, randomized, double-blind, placebo-controlled, crossover study. Journal of Herbal Pharmacotherapy. 2005; 5(4): 1-11. [PMID: 16635963]

2. The German 1-Year GRANU Study on Pumpkin Seed (Cucurbita pepo):

A large-scale, 12-month multicenter study involving 1,431 men aged 50–80 demonstrated that pumpkin seed significantly reduced the International Prostate Symptom Score (IPSS) and substantially lowered nighttime bathroom visits (nocturia) while being remarkably well tolerated.

Citation: Vahlensieck W, Theurer C, Pfitzer E, et al. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urologia Internationalis. 2015; 94(3): 286-295. [PMID: 25196580]

3. Synergistic Combination of Saw Palmetto and Nettle Root:

A 96-week multicenter trial evaluated men with lower urinary tract symptoms taking combined saw palmetto and nettle extract. Over the observation period, total IPSS scores dropped by 53%, average urinary flow rate increased by 19%, and residual bladder urine decreased by 44%.

Citation: Lopatkin N, Sivkov A, Schläfke S, et al. Efficacy and safety of a combination of Sabal and Urtica extract in lower urinary tract symptoms - long-term follow-up of a placebo-controlled, double-blind, multicenter trial. World Journal of Urology. 2005; 23(2): 139-146. [PMID: 15928959]

Supplement Facts & Recommended Usage

Supplement Facts

Serving Size: 2 VegCaps  |  Servings Per Container: 50

* Daily Value not established.

Directions for Daily Use

Suggested Dosage: Take 2 VegCaps three times daily with a meal or a large glass of water (a total daily intake of 6 capsules, supplying 3,000 mg of the botanical blend). Taking capsules alongside meals optimizes the intestinal assimilation of fat-soluble phytosterols.

Consistency Note: Natural herbal constituents build up active compounds in prostate tissues gradually. While many men report improved comfort within 2 to 4 weeks, clinical benchmarks show optimal results typically manifest after 60 to 90 days of consistent daily use.

Important Safety Information & Contraindications

To ensure maximum safety and avoid herb-drug interactions, review the following clinical warnings before starting Solaray Prostate Blend SP-16:

• Medical Supervision: Always keep your licensed healthcare practitioner informed when introducing any new botanical supplement into your health routine.
• Kidney Disease: Do not use this formula if you suffer from inflammatory kidney disease or renal insufficiency.
• Gallbladder & Gallstones: Ginger and burdock root stimulate bile flow; consult your doctor prior to use if you have diagnosed gallstones or bile duct obstructions.
• Thyroid Health: Because kelp is a natural source of iodine, this product is contraindicated for individuals with hyperthyroidism.
• Duration: Not recommended for excessive or indefinite, unsupervised long-term use. Routine clinical evaluations (including annual PSA blood testing and digital rectal examinations) are critical for all men over 50.
• Keep Out of Reach of Children: Do not use if safety seal around cap is broken or missing. Store in a cool, dry location away from direct sunlight.

Frequently Asked Questions (FAQ)

What is Solaray Prostate Blend SP-16 used for?

Solaray Prostate Blend SP-16 is a specialized herbal dietary supplement crafted to promote normal prostate size, enhance urinary flow velocity, minimize waking up during the night to urinate, and soothe the entire bladder and urinary tract lining.

How long does it take for Prostate Blend SP-16 to work?

Individual results vary, but most men experience noticeable improvements in bladder comfort and urine flow within 2 to 4 weeks of consistent intake. Maximum clinical benefits from herbal phytosterols typically occur after 8 to 12 weeks of continuous daily use.

Can I take Prostate Blend SP-16 if I am already taking prescription prostate medication?

If you are currently taking prescription pharmaceutical medications such as alpha-blockers (tamsulosin/Flomax) or 5-alpha-reductase inhibitors (finasteride/Proscar), consult your urologist before starting SP-16 to prevent redundant pharmacological effects or drug-herb interactions.

Why does the label advise against use with hyperthyroidism?

The formula contains sea kelp (Laminaria spp.), an abundant natural source of organic iodine. Excessive iodine intake can stimulate the thyroid gland, which is unsafe for people with an overactive thyroid condition.

Does this supplement cure or treat prostate cancer?

No. Solaray Prostate Blend SP-16 is a nutritional supplement designed to support normal glandular and urinary function. It is not intended to diagnose, treat, cure, or prevent prostate cancer or any other medical condition. Regular check-ups with your doctor are essential.