Give your cardiovascular and respiratory systems the targeted, cellular cleanup support they deserve. Solaray Nattokinase and Serrapeptase unites two of nature’s most effective proteolytic (protein-cleaving) enzymes to break down stubborn cellular debris, maintain elastic blood vessels, and soothe congested sinus passages.
✓ 3,000 FU Active Nattokinase ✓ 60,000 Units Potent Serrapeptase ✓ Acid-Shielding Enteric Coating ✓ 100% Vegetarian & Lab VerifiedMany people know about digestive enzymes that help break down the food you eat, but systemic enzymes do something entirely different. When absorbed into your bloodstream on an empty stomach, they operate like a dedicated cleanup crew traveling through your circulatory and lymphatic pathways.
Think of your blood vessels like clear-running streams: over time, microscopic debris made of an adhesive structural protein called fibrin can build up. While fibrin is needed to stop bleeding from cuts, excess fibrin can thicken your blood, make vessel walls stiff, and trap fluid in swollen, uncomfortable tissues.
Extracted from the traditional Japanese fermented food natto, nattokinase is a natural fibrin-dissolving specialist. It specifically identifies and slices through excessive, stubborn fibrin webs inside blood vessels, encouraging smooth arterial dilation, healthy blood viscosity, and balanced blood pressure.
Originally discovered in the digestive tract of silkworms (now cleanly cultivated via friendly bacterial fermentation), serrapeptase safely digests dead tissue, inflammatory proteins, and thick mucus without harming living cells. It is widely praised for clearing nasal pathways and soothing irritated joint tissues.
Unlike generic supplement blends based on guesswork, both nattokinase and serrapeptase are backed by extensive human clinical trials and biochemical evaluations:
✓ Direct Carotid Plaque and Artery Support
In a 12-month clinical study involving 1,062 human participants, daily nattokinase supplementation demonstrated substantial, statistically significant reductions in both carotid plaque thickness and carotid intima-media thickness (CCA-IMT), while promoting healthier lipid balances.
Clinical Citation: Chen H, Chen J, Zhang F, et al. Effective management of atherosclerosis progress and hyperlipidemia with nattokinase: A clinical study with 1,062 participants. Front Cardiovasc Med. 2022;9:964977. PMID: 36172235.
✓ Multi-Path Fibrin Dissolution & Blood Flow
Clinical evaluations demonstrate that oral nattokinase acts through multiple vascular protective pathways: it breaks down cross-linked fibrin networks directly, supports the body's natural tissue plasminogen activator (t-PA), and reduces inhibitors that cause sluggish blood flow.
Clinical Citation: Weng Y, Yao J, Sparks S, Wang KY. Nattokinase: An Oral Antithrombotic Agent for the Prevention of Cardiovascular Disease. Int J Mol Sci. 2017;18(3):523. PMID: 28264497.
✓ Respiratory Secretion Breakdown & Sinus Comfort
Double-blind, placebo-controlled human trials show that serrapeptase (serratiopeptidase) thins dense nasal and bronchial mucus, allowing the respiratory system to flush out congested fluids quickly and restoring easy, unobstructed airflow through the sinuses.
Clinical Citation: Mazzone A, Catalani M, Costanzo M, et al. Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind, randomized trial versus placebo. J Int Med Res. 1990;18(5):379-388. PMID: 2258169.
Many ordinary enzyme supplements fail before they ever get the chance to work. Your stomach relies on strong digestive acid (pH 1.5 to 3.5) to dissolve protein. If delicate systemic enzymes like serrapeptase and nattokinase are unprotected, that harsh acid will destroy them, breaking them down into inactive amino acids.
How Solaray Protects Every Single VegCap:
Solaray manufactures each batch under strict cGMP pharmaceutical standards, with every lot tested by independent third-party laboratories for purity and potency.
Serving Size: 1 VegCap | Servings Per Container: 30
Amount Per Serving % Daily Value Nattokinase (Soybean Fibrinase)* Daily Value not established.
Vegetable cellulose capsule, cellulose, maltodextrin, silica, magnesium stearate, and enteric coating.
Allergen Notice: Contains soy. Free from artificial flavorings, synthetic preservatives, and animal gelatin. 100% Vegan formula.
Take one (1) VegCap daily on an empty stomach with an 8-ounce glass of water. For best results, take it at least 60 minutes before your morning meal or two hours after eating. Taking systemic enzymes with food causes them to digest your food instead of working systemically inside your bloodstream.
While both are protein-cleaving systemic enzymes, they specialize in different areas. Nattokinase primarily focuses on cardiovascular health by clearing away excess fibrin webs in blood vessels, preventing thick sluggish blood, and maintaining arterial elasticity. Serrapeptase is broader, specializing in clearing dead cellular debris, soothing joint irritation, and liquefying dense mucous fluids in congested sinuses and airways.
If you consume these enzymes with food, they will immediately begin breaking down the proteins in your meal, acting as digestive aids. To support your cardiovascular, circulatory, and sinus health, the enzymes must remain unattached so they can pass into your small intestine, absorb directly into your bloodstream, and circulate throughout your body.
"FU" stands for Fibrinolytic Units. It is an internationally recognized scientific measurement of the enzyme's active potency — specifically its ability to dissolve fibrin. Milligrams (mg) only tell you the physical weight of the powder in the capsule, whereas FU verifies how active and effective the enzyme is. Solaray provides 3,000 FU per serving, surpassing standard 2,000 FU formulas.
No, not unless you are under the direct supervision of your physician or cardiologist. Because nattokinase naturally thins and clears circulatory pathways, taking it alongside medications like warfarin, Eliquis, Plavix, or high-dose aspirin can increase your chance of bleeding or bruising.
For sinus drainage and clearer nasal airways, many people notice positive changes within 3 to 7 days. For cardiovascular goals like healthy arterial flexibility, balanced blood pressure, and long-term circulatory support, clinical studies evaluate benefits over 8 to 26 weeks of consistent daily usage.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. VitaNet® LLC reminds customers that dietary supplements must be used responsibly and under the supervision of a licensed physician, especially when managing cardiovascular or circulatory health conditions.
Scientific References:
1. Sumi H, et al. A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese Natto. Experientia. 1987;43(10):1110-1111.
2. Chen H, et al. Effective management of atherosclerosis progress and hyperlipidemia with nattokinase: A clinical study with 1,062 participants. Front Cardiovasc Med. 2022;9:964977.
3. Weng Y, et al. Nattokinase: An Oral Antithrombotic Agent for the Prevention of Cardiovascular Disease. Int J Mol Sci. 2017;18(3):523.
4. Mazzone A, et al. Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology. J Int Med Res. 1990;18(5):379-388.
5. Tiwari M. The role of serratiopeptidase in the resolution of inflammation. Asian J Pharm Sci. 2017;12(3):209-215.
Review of Nattokinase and Serrapeptase - Solaray Product 93714
Reviewed by
Wednesday, May 11, 2011
looks like it a great product and the biggest thing is that it has great health benefits plus more exciting thing is that they are giving 43% discount which makes it even more desiring to get. we can get great health benefits in only only bucks which is pretty cool .
mpls, mn usa
