NOW: L-GLUTAMINE 1000mg 240 CAPS

L-GLUTAMINE 1000mg - 240 CAPS



by   NOW FOODS
*MSRP:
$47.99
Our Price:
$28.80
Buy: at $28.80
(3 for $ 28.79ea. = $ 86.37 ) 40% OFF MSRP
UPC: 733739000910
# N0091

Product Overview & Quick Specs

Think of your digestive tract like a busy highway system that runs on special fuel. NOW L-Glutamine 1,000 mg supplies pure crystalline fuel directly to that network. This unbonded amino acid (free-form L-Glutamine) nourishes your digestive tract lining (enterocytes) while protecting your body's active immune defenses [1, 2].

  • ✓ Active Form & Potency: 1 g (1,000 mg) of pure, crystalline Free-Form L-Glutamine (C5H10N2O3) per single vegetarian capsule.
  • ✓ Primary Target: Intestinal wall cell renewal, systemic nitrogen transport, and active white blood cell defense pathways [1, 2].
  • ✓ Supply & Value: 240 full servings per bottle (an economical 4 to 8 month supply) delivering twice the potency of standard 500 mg capsules.
  • ✓ Purity & Dietary Status: 100% vegetarian capsule, non-GMO, bottled in 100% PCR recycled resin, and free of gluten, soy, dairy, egg, fish, and nuts.

Buyer's Guide & Form Comparison

Why the Free-Form Capsule Matters

Think of whole dietary protein like an unbroken chain of heavy cargo cars. Your stomach acid and enzymes must break every link before absorption starts. This formula provides free-form amino acids (unbonded L-Glutamine), which act like individual packages ready for direct cellular uptake [1]. Mass-market big box store brands often utilize low-grade amino acids prone to chemical impurities. NOW delivers laboratory-verified, pure crystalline glutamine with twice the strength of common capsules to reduce daily pill fatigue [1, 3].

Is This Formula Right for You?

Best Choice For:

  • ✓ Shoppers seeking daily intestinal barrier support in a high-potency capsule without the hassle of mixing powders [2, 3].
  • ✓ Active athletes needing efficient nitrogen delivery for muscle tissue maintenance after intense training sessions [1, 5].
  • ✓ Individuals wanting clean immune nourishment without synthetic fillers, animal gelatin, or common allergens [1, 4].

Consider Another Option If:

  • ✗ You require intensive athletic megadoses (10 to 20 grams daily), where standalone unflavored powder is more practical.
  • ✗ You struggle with swallowing larger dietary capsules and prefer liquids.
  • ✗ You have severe liver challenges or specific metabolic conditions requiring formal medical supervision.
The VitaNet® Promise: Backed by our 31-year family-owned heritage, every purchase includes our unconditional 100% money-back guarantee—even on opened bottles—so you can evaluate your digestive comfort completely risk-free.

How It Works in the Body

Think of amino acids as structural bricks for your cellular house. Your body manufactures some L-Glutamine naturally. During physical stress or workout exhaustion, your reserves empty rapidly, making it conditionally essential [1, 5].

1. Locking the Cellular Zipper of the Gut Barrier

Think of your intestinal wall like a protective jacket zipper. The individual teeth represent mucosal lining cells (enterocytes). These intestinal cells consume L-Glutamine as primary cellular fuel [1, 2]. Providing adequate glutamine helps keep specialized protein seals (tight junctions) locked firmly shut. This structural bond prevents unwanted debris from crossing into your bloodstream while letting nutrients pass freely [2, 3].

2. Operating as a Safe Nitrogen Delivery Vehicle

Think of nitrogen like hazardous cargo on an interstate highway. Your tissues require nitrogen (N2) for muscle repair. However, normal metabolism creates toxic ammonia (NH3) as waste. L-Glutamine acts like a heavy-duty tanker: it safely locks up free nitrogen, neutralizes it, and ferries it across tissues [1, 5]. In the kidneys, it releases ammonium (NH4+) to preserve a healthy acid-base balance [1, 2].

3. Supplying Fuel to Immune First Responders

Think of white blood cells like emergency rescue teams responding to a call. When immune defense activates, specialized white blood cells (lymphocytes and macrophages) multiply at rapid speeds [1, 4]. Clinical research confirms that active immune cells burn L-Glutamine just as fast as glucose [1, 4]. Supplying supplemental glutamine ensures your defensive cells keep the cellular energy they need for daily resilience [1, 4].

Daily Timing, Synergy & Realistic Timelines

Best Time to Take

Take 1 capsule 1 to 3 times daily, preferably on an empty stomach or between meals with 8 ounces of water (H2O) or juice. Specialized transport gateways in the gut wall absorb free amino acids [1]. If taken with whole proteins like meat or dairy, competing amino acids crowd those entry doors. Taking capsules between meals ensures fast, unhindered absorption [1].

Daily Schedule & Dosing Strategy

Space your capsules throughout the day to keep cellular levels steady:

  • ✓ Morning Fasted Dose: Take 1 capsule right after waking up to nourish resting gut lining cells after overnight fasting [2].
  • ✓ Post-Workout Window: Take 1 capsule 30 minutes following exercise to replenish nitrogen stores burned during training [1, 5].
  • ✓ Evening Bedtime Support: Take 1 capsule 30 minutes before sleep to support tissue rebuilding during rest [1, 4].

Smart Pairings & Spacing Rules

  • ✓ Complementary Nutrients: Pairs effectively with daily probiotics (supporting microbiome diversity) and Zinc Carnosine for total gastrointestinal lining maintenance.
  • ✗ Liquid Temperature Warning: Never swallow capsules with boiling hot tea or coffee. Excessive heat breaks delicate amino acid chemical structures. Always use cool or room-temperature liquids.

What to Expect Over Time

Days 1–7: Rapid cellular uptake begins across the digestive tract. Mucosal cells use free glutamine immediately, promoting digestive comfort and stomach ease [2].

Weeks 3–4: Consistent daily intake reinforces intestinal tight junctions, sustaining gut barrier integrity and promoting regular immune defense responsiveness [1, 3].

Months 2–3+: Cumulative nitrogen balance promotes muscular recovery, healthy structural tissue retention, and lasting everyday vitality [1, 5].

Physical Feel, Sensory Traits & Clean Ingredients

Pill Format & Ease of Use

NOW encapsulates this double-strength formula in clear vegetarian capsules (standard Size "00", measuring approximately 23 mm in length). The smooth plant cellulose shell glides easily down the throat with water, avoiding the chalky texture of large compressed tablets. If you dislike swallowing capsules, pull the two halves apart and stir the pure white powder into cool water, juice, or a smoothie.

Natural Aroma, Taste & Color

The sealed capsule is completely odorless and flavorless. When opened, pure L-Glutamine powder has a mild, clean, faintly sweet taste that dissolves completely with zero lingering bitterness. Natural color variations from bright white to off-white may occur naturally between manufacturing lots.

Other Ingredients Explained

Every non-active ingredient in this clean formula serves an essential functional purpose:

  • ✓ Hypromellose (cellulose capsule): A 100% vegetarian shell derived from softwood plant fiber. It contains zero animal gelatin and dissolves quickly in gastric fluid.
  • ✓ Stearic Acid (vegetable source): A natural plant-derived fatty acid used as a clean manufacturing lubricant to ensure precise capsule filling without synthetic additives.
  • ✓ Silicon Dioxide: A natural food-grade mineral compound that absorbs ambient moisture and prevents fine amino acid crystals from clumping during encapsulation.

Proper Storage

Free-form amino acids naturally attract moisture from the air. Keep your bottle tightly sealed in a cool, dry, dark pantry or cabinet after opening. Avoid storage in humid environments like bathrooms or near kitchen stovetops. The bottle is made from 100% PCR (post-consumer recycled) resin to support environmental sustainability.

Manufacturer Quality & Lab Testing Standards

Never gamble your health on cheap big box store brands. Many generic discount supplements sold at mass retailers are made by contract packagers that skip vital safety testing. Independent audits frequently discover that discount amino acids carry heavy metals, unlisted fillers, or fake nitrogen spikes. NOW Foods protects your family by maintaining private in-house testing protocols that exceed industry benchmarks:

  • ✓ ISO/IEC 17025:2017 Accredited Laboratories: NOW conducts over 19,000 analytical tests every month in their world-class facilities to verify raw material authenticity and finished product safety.
  • ✓ ICP-MS Heavy Metal Testing (Parts-Per-Billion Precision): Using Inductively Coupled Plasma Mass Spectrometry, every incoming lot is screened for lead, arsenic, cadmium, and mercury to beat USP and California Proposition 65 limits.
  • ✓ HPLC Molecular Potency Verification: High-Performance Liquid Chromatography verifies that each capsule delivers 100% true L-enantiomer free-form glutamine with zero synthetic adulteration.
  • ✓ Microbiological Pathogen Bio-Screening: Production batches undergo rigorous microbial plating to confirm the complete absence of Salmonella spp., Escherichia coli, and Staphylococcus aureus.
  • ✓ Audited cGMP Manufacturing: Facilities are independently audited and certified by UL Solutions and maintain an "A-rated" cGMP registration through the Natural Products Association (NPA).

Complete Supplement Facts Panel

Supplement Facts

Serving Size: 1 Veg Capsule

Servings Per Container: 240

Description Amount per Serving % Daily Value
L-Glutamine (Free-Form) 1 g (1,000 mg) **

** Daily Value not established.

Other Ingredients: Hypromellose (cellulose capsule), Stearic Acid (vegetable source) and Silicon Dioxide.

Allergen Notice: Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Caution: For adults only. Consult physician if pregnant/nursing, taking medication, or have a medical condition. Keep out of reach of children.

This double strength product has twice the L-Glutamine (1,000 mg per capsule) as in our regular strength product (500 mg per capsule).

Natural color variation may occur in this product. Store in a cool, dry, dark place after opening. This bottle is made from 100% PCR (post-consumer recycled) resin. Made and quality tested in the USA with globally sourced ingredients.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Scientific References & Clinical Studies

  1. Cruzat V, Macedo Rogero M, Noel Keane K, Curi R, Newsholme P. "Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation." Nutrients, 2018;10(11):1564. [PubMed PMID: 30360490]
  2. Rao R, Samak G. "Role of Glutamine in Protection of Intestinal Epithelial Tight Junctions." Journal of Epithelial Biology & Pharmacology, 2012;5(Suppl 1-M7):47-54. [PubMed PMID: 25815120]
  3. Wang B, Wu G, Zhou Z, Dai Z, Sun Y, Ji Y, Li W, Wang W, Liu C, Han F, Wu Z. "Glutamine and intestinal barrier function." Amino Acids, 2015;47(10):2143-2154. [PubMed PMID: 25773475]
  4. Calder PC, Yaqoob P. "Glutamine and the immune system." Amino Acids, 1999;17(3):227-241. [PubMed PMID: 10582115]
  5. Gleeson M. "Dosing and efficacy of glutamine supplementation in human exercise and sport training." The Journal of Nutrition, 2008;138(10):2045S-2049S. [PubMed PMID: 18806122]

Frequently Asked Questions

Can I open this NOW L-Glutamine capsule and mix the powder into a drink?

Yes. You can gently pull the two capsule halves apart and stir the pure white powder into cool water, fruit juice, or a smoothie. The unflavored powder dissolves cleanly with a mild, neutral taste. Avoid mixing it into boiling hot liquids, because intense heat breaks delicate amino acid bonds.

How does this 1,000 mg double-strength capsule compare to the 500 mg version?

This double-strength formula provides exactly 1,000 mg of pure free-form L-Glutamine per single capsule, which is twice the potency of the regular 500 mg version. It delivers the same pure amino acid while cutting your daily pill count in half, offering greater convenience and value.

Will taking NOW L-Glutamine capsules break an intermittent fast?

No. A single 1,000 mg capsule contains virtually zero calories, carbohydrates, or fats, and will not trigger a meaningful insulin spike. Taking free-form glutamine with plain water during your fasting window delivers direct, unhindered fuel straight to resting intestinal lining cells.

Can I take this capsule at the same time as my daily probiotic or multivitamin?

Yes, taking L-Glutamine alongside a daily probiotic is highly beneficial. Probiotics supply helpful active bacteria, while L-Glutamine provides direct cellular fuel to support the physical intestinal barrier. For maximum absorption, take your glutamine capsule on an empty stomach with cool water.

Why is free-form L-Glutamine superior to the glutamine in protein shakes or big box store brands?

Glutamine in whey or whole protein is locked inside long peptide chains that require slow digestive breakdown. In contrast, free-form L-Glutamine is completely unbonded and ready for immediate absorption. Furthermore, NOW utilizes in-house ISO-accredited testing to verify absolute purity, protecting you from heavy metals and fillers commonly found in generic store brands.

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