Nighttime Muscle Tissue Preservation, Delayed-Onset Muscle Soreness (DOMS) Attenuation & Deep Restorative Sleep Formula
Discover the key to rejuvenating your body with the NOW® R & R Rest and Repair formula, a revolutionary blend designed to promote restful sleep*, preserve lean mass, and reduce post-workout soreness. This scientifically advanced supplement is tailor-made for athletes, weightlifters, and active individuals who push their physical limits and understand that true adaptation happens during recovery.
Intense physical exertion imposes a two-fold toll on the body: micro-tears in contractile muscle tissue and sympathetic central nervous system (CNS) overstimulation. NOW® Sports R&R Rest and Repair bridges the gap between muscular restoration and nocturnal recovery. By combining clinically evaluated anti-catabolic agents with neurotransmitter precursors, this formula works synergistically while you sleep to shut down proteolysis, blunt exercise-induced oxidative stress, and facilitate restorative deep sleep cycles.
Key Performance & Recovery Highlights
Preserves Lean Muscle Mass: Delivers pure myHMB® to blunt overnight muscle proteolysis and stimulate mTOR signaling.*
Reduces Post-Workout Soreness: Concentrated CherryPURE® Montmorency tart cherry powder neutralizes free radicals and mitigates DOMS.*
Promotes Restful Sleep Architecture: Blends GABA, 5-HTP, and 5 mg Melatonin to accelerate sleep onset latency and extend slow-wave non-REM sleep.*
Replenishes Intramuscular Glutamine: Supports whole-body nitrogen retention and enterocyte gut mucosal repair after exhaustive workouts.*
Informed-Sport Certified: Rigorously tested for banned substances, synthetic adulterants, and prohibited athletic compounds.
During nocturnal fasting, cortisol elevations can accelerate muscle protein breakdown (MPB). This formula contains HMB (ß-Hydroxy ß-Methylbutyrate), the active leucine metabolite licensed as myHMB®. HMB acts directly on muscle cells by downregulating the ubiquitin-proteasome proteolytic pathway—the primary mechanism responsible for muscle atrophy. Concurrently, it upregulates protein synthesis via the mTOR pathway to safeguard hard-earned lean muscle mass.
To address delayed-onset muscle soreness, the formula incorporates clinically tested CherryPURE® Tart Cherry powder (Prunus cerasus). Rich in anthocyanins and procyanidins, tart cherry extract works as a natural cyclooxygenase (COX-1 and COX-2) modulator. Clinical research demonstrates that supplementing with tart cherry polyphenols significantly blunts serum lipid peroxidation and creatine kinase (CK) spikes, accelerating isometric muscle strength recovery following intense training.
Pillar 2: CNS Down-Regulation & Circadian Staging
Hard training fires up the sympathetic "fight-or-flight" nervous system. Rest and Repair counters this with high-potency GABA (Gamma-Aminobutyric Acid), the body's chief inhibitory neurotransmitter, which diminishes post-synaptic excitatory signaling to calm a racing mind.
To support natural sleep staging, the formula integrates 5-HTP (5-Hydroxytryptophan) extracted from Griffonia simplicifolia seed, paired with Vitamin B-6 (Pyridoxine HCl). Vitamin B-6 acts as an indispensable enzymatic cofactor in the aromatic L-amino acid decarboxylase step, converting 5-HTP into endogenous serotonin (5-HT). Serotonin serves as the immediate direct biochemical precursor to pineal melatonin. A targeted 5 mg dose of pure Melatonin synchronizes circadian sleep cycles, promoting deeper Stage 3 and Stage 4 non-REM sleep where human growth hormone (HGH) release reaches its physiological peak.
Other Ingredients: Hypromellose (cellulose capsule), Microcrystalline Cellulose, Stearic Acid (vegetable source), and Silicon Dioxide.
Allergen Information: Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut, or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
Trademarks: Nutritional uses of Calcium ß-Hydroxy ß-Methylbutyrate Monohydrate (HMB) are licensed to NOW Health Group, Inc. Use of the trademark myHMB® is licensed from Metabolic Technologies, LLC. CherryPURE® is a registered trademark of Shoreline Fruit, LLC.
Made and quality tested in the USA with globally sourced ingredients.
Suggested Usage & Bedtime Protocol
Directions: Take 3 veg capsules daily, approximately 30 to 60 minutes before bedtime with water. For optimal muscle preservation and DOMS attenuation, maintain consistent daily use on both training and rest days.
Cautionary Guidance & Contraindications
For adults only at bedtime. Not intended for pregnant or nursing women. May cause drowsiness and mild transient GI symptoms; take with food in case of GI upset. Do not consume in conjunction with alcoholic beverages, when driving a motor vehicle, or while operating machinery. Consult a physician if taking medication (especially sedatives, antidepressants, or SSRIs) or if you have a medical condition (including liver disease, bipolar disorder, depressive disorders, hypertension, or epilepsy). Keep out of reach of children. Store in a cool, dry, dark place after opening.
Frequently Asked Questions
What makes NOW Sports R&R Rest and Repair different from standard sleep aids?
Standard sleep aids focus solely on sedation via antihistamines or plain melatonin, ignoring physical tissue trauma. NOW® Sports R&R Rest and Repair pairs sleep compounds (Melatonin, 5-HTP, GABA) with physical recovery drivers: patented myHMB® to blunt catabolic muscle proteolysis and CherryPURE® Tart Cherry powder to downregulate exercise-induced inflammation and muscle soreness (DOMS).
How does the combination of HMB and CherryPURE® reduce post-workout soreness?
HMB directly downregulates the ubiquitin-proteasome pathway, reducing muscle protein breakdown during overnight recovery. Meanwhile, CherryPURE® delivers tart cherry anthocyanins that scavenge reactive oxygen species (ROS) and modulate inflammatory prostaglandins. This dual approach curbs muscle damage markers and accelerates baseline strength recovery.
Should I take NOW Foods R&R Rest and Repair on non-workout days?
Yes. Skeletal muscle remodeling and myofibrillar repair continue for 24 to 72 hours following exhaustive exercise. Consuming R&R Rest and Repair on non-training days maintains systemic nitrogen retention via L-Glutamine and HMB, while preserving consistent circadian sleep rhythms.
Will this supplement cause next-morning grogginess?
The formula contains 5 mg of Melatonin alongside GABA and 5-HTP, engineered for a complete 7 to 9-hour sleep cycle. If you take the dose with fewer than 7 hours of dedicated sleep time remaining, you may encounter mild transient drowsiness. Ensure a full sleep window for clear-headed waking.
Can I stack R&R Rest and Repair with an evening casein protein shake?
Yes. Slow-digesting proteins like micellar casein provide a steady stream of amino acids for protein synthesis, while NOW Sports R&R Rest and Repair supplies the targeted anti-catabolic, anti-inflammatory, and neurochemical sleep precursors to optimize the cellular repair environment.
Is this formula batch-tested for athletic banned substances?
Yes. The NOW® Sports line participates in the Informed-Sport program. Each production lot is evaluated via ISO 17025 accredited methods for over 220 banned athletic compounds, assuring tested purity for competitive athletes.