A high-potency, multi-pathway magnesium supplement engineered to support daily muscle comfort, peaceful sleep, steady nerve signaling, and cellular energy – formulated to absorb smoothly without the stomach sensitivity common to standard mineral tablets.
Medical & Editorial Review Notice: This educational guide integrates clinical findings from peer-reviewed journals including PLoS ONE, Biological Trace Element Research, and Magnesium Research. It adheres to dietary supplement standards under the Dietary Supplement Health and Education Act (DSHEA) and National Institutes of Health (NIH) nutritional intake benchmarks.
Quick Facts: Why Ultra-Mag Stands Out
✓400 mg Elemental Magnesium: Fulfills up to 95%–100% of the Daily Value in two convenient daily tablets.
✓5 Synergistic Bioavailable Forms: Citrate, Glycinate, Malate, Taurinate, and Succinate work through multiple digestive absorption pathways.
✓Enhanced with Active Vitamin B6: 30 mg of Pyridoxine HCl acts as an intracellular escort, helping magnesium pass into muscle and nerve cells.
✓Gentle on Digestion: Buffered organic chelates avoid drawing excessive water into the bowel, minimizing the laxative effect of cheap magnesium oxides.
✓Hypoallergenic & Vegetarian: Contains zero dairy, gluten, soy, wheat, egg, artificial colors, or artificial preservatives.
✓Third-Party Quality Verified: Manufactured by Source Naturals under strict cGMP (Current Good Manufacturing Practices) quality certifications.
Understanding Magnesium: The Spark Plug & The Brake Pedal
Magnesium is involved in over 300 essential biochemical reactions across every tissue in the body. If your cells were an engine, magnesium plays two distinct, critical roles:
1. The Cellular Spark Plug (Energy Creation)
Every bit of biological physical energy you generate relies on a tiny molecule called Adenosine Triphosphate (ATP). However, ATP cannot become active on its own; it must bind directly to a magnesium ion to create Mg-ATP. Without sufficient magnesium, your cellular energy plants (mitochondria) cannot turn fuel into stamina, leading to persistent mental and physical fatigue.
2. The Physiological Brake Pedal (Relaxation & Calm)
While calcium acts like an accelerator pedal—telling muscle fibers to contract and nerves to fire—magnesium functions as the natural brake pedal. It displaces calcium, instructing your muscle tissues to loosen, easing cramps, and soothing over-excited nerves by stimulating calm neurotransmitters like GABA.
According to research published in the British medical journal Open Heart (DiNicolantonio et al., 2018), up to 50% of the US population does not consume sufficient magnesium due to soil mineral depletion and refined food processing. This widespread shortfall often presents as nighttime leg twitching, tense neck muscles, occasional tension headaches, daytime fatigue, and difficulty winding down before sleep.
The 5-in-1 Advantage: Why Multiple Magnesium Forms Outperform Single Salts
Most budget magnesium supplements use cheap magnesium oxide. Clinical trials demonstrate that magnesium oxide has an absorption rate as low as 4% (Firoz & Graber, 2001). Because the gut struggles to absorb oxide, the unabsorbed mineral lingers in the colon, drawing in water and causing loose stools or diarrhea before your tissues ever absorb the benefits.
Source Naturals Ultra-Mag solves this bottleneck by combining five gentle, biologically active forms. Each form attaches to a different carrier molecule, allowing the body to absorb magnesium through multiple parallel transport pathways:
Magnesium Form
Target Tissue & Pathway
Primary Health Benefit
Magnesium Glycinate (Chelate)
Central nervous system & intestinal lining via amino acid transport channels
Bound to the calming amino acid glycine; crosses cell walls effortlessly, promotes restful sleep, and is exceptionally gentle on digestion.
Magnesium Malate
Skeletal muscle fibers & mitochondrial energy cycles
Bonded to malic acid (a key player in cellular Krebs cycle energy production); specifically studied for relieving muscle soreness, stiffness, and physical fatigue.
Magnesium Taurinate
Cardiovascular walls, heart tissue & vascular tone
Bound to the amino acid taurine; supports steady heart rhythms, endothelial vascular health, and healthy blood pressure within normal ranges (McCarty, 1996).
Magnesium Citrate
Soft tissue, systemic circulation & digestion
An organic acid bond known for high bio-solubility in the upper digestive tract; gently assists normal gastrointestinal transit and digestive rhythm.
Magnesium Succinate
Aerobic cellular respiration & metabolic support
Utilizes succinic acid to support the electron transport chain inside the cell, helping sustain stamina and athletic endurance.
The Vitamin B6 Connection: Why Synergistic Absorption Matters
Many standalone magnesium supplements stop at the mineral itself. Ultra-Mag includes 30 mg of Vitamin B-6 (as pyridoxine HCl) per serving. This is not an arbitrary filler – it serves a direct physiological purpose.
Clinical Evidence: The Pouteau Trial (2018)
In a landmark randomized, single-blind clinical study published in PLoS ONE (Pouteau et al., 2018), researchers examined individuals with low blood magnesium levels. The clinical trial established that combining magnesium with Vitamin B6 led to a 24% greater improvement in perceived stress relief compared to magnesium administered alone. Vitamin B6 acts as an enzymatic cofactor that accelerates the transport of magnesium across cell membranes, ensuring the mineral reaches the inner compartment of the cell where it is utilized.
By pairing B6 with five bioavailable chelates, Ultra-Mag provides your neuromuscular system with both the mineral and the molecular key needed to absorb it.
Source Naturals maintains uncompromising transparency. Below is the exact nutritional breakdown for SKU: SN0802 (60 Tablets / 30-Day Supply), also available in 120 and 240 tablet sizes.
Supplement Facts
Serving Size: 2 Tablets | Servings Per Container: 30
* Percent Daily Values (%DV) are based on a 2,000 calorie diet.
Other Ingredients: Stearic acid, acacia gum, modified cellulose gum, hydroxypropyl cellulose, magnesium stearate, and colloidal silicon dioxide (silica).
Allergen Free Guarantee: Contains no yeast, dairy, egg, gluten, soy, or wheat. Contains no sugar, preservatives, artificial flavors, artificial colors, or fragrance. Suitable for vegetarians.
Suggested Use, Best Practices & Safety Precautions
Recommended Dosage
Take 1 or 2 tablets daily with a meal, or as recommended by your healthcare professional. Many individuals prefer taking 1 tablet with dinner and 1 tablet 45 minutes before bedtime to encourage nocturnal muscle relaxation and restful sleep.
Always Take With Food
Consuming magnesium alongside whole food stimulates gastric acid secretion, which aids mineral ionization and promotes smoother passage through the duodenal wall into circulation.
Kidney Health Advisory
The kidneys are responsible for filtering and clearing excess magnesium. Individuals with severe kidney disease, impaired renal function, or heart block should not take magnesium supplements unless directly prescribed by a nephrologist.
Medication Timing & Interactions
Magnesium can bind to certain pharmaceutical drugs in the stomach. Separate your Ultra-Mag dose by at least 2 to 3 hours from oral tetracycline/fluoroquinolone antibiotics, thyroid hormones (levothyroxine), or bisphosphonates.
Verified Scientific Citations & Clinical Evidence
Our content is rigorously supported by published medical literature to guarantee factual precision and consumer safety:
Pouteau, E., Kabir-Ahmadi, M., Noah, L., Mazur, A., et al. (2018). Superiority of magnesium and vitamin B6 combination over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial. PLoS ONE, 13(12), e0208454. DOI: 10.1371/journal.pone.0208454.
Firoz, M., & Graber, M. (2001). Bioavailability of US commercial magnesium preparations. Magnesium Research, 14(4), 257–262. PMID: 11794633.
Uysal, N., Kizildag, S., Yuce, Z., Guvendi, G., et al. (2019). Timeline (Bioavailability) of Magnesium Compounds in Hours: Which Magnesium Compound Works Best? Biological Trace Element Research, 187(1), 128–136. DOI: 10.1007/s12011-018-1351-9.
McCarty, M. F. (1996). Complementary vascular and metabolic effects of magnesium and taurine: A rationale for magnesium taurate. Medical Hypotheses, 46(2), 89–100. DOI: 10.1016/s0306-9877(96)90007-9.
Abraham, G. E., & Flechas, J. D. (1992). Management of Fibromyalgia: Rationale for the Use of Magnesium and Malic Acid. Journal of Nutritional Medicine, 3(1), 49–59.
DiNicolantonio, J. J., O'Keefe, J. H., & Wilson, W. (2018). Subclinical magnesium deficiency: A principal driver of cardiovascular disease and a public health crisis. Open Heart, 5(2), e000668. DOI: 10.1136/openhrt-2018-000668.
Frequently Asked Questions (FAQ)
1. Why does Ultra-Mag combine 5 forms of magnesium instead of just one?
Different tissues in your body utilize different transport mechanisms. Magnesium glycinate easily penetrates nerve tissue and crosses the blood-brain barrier; magnesium malate directly fuels muscle mitochondria and cellular ATP; magnesium taurinate supports vascular tone and cardiovascular rhythm; and citrate delivers high ionic solubility. Combining all five ensures comprehensive physical coverage without relying on a single digestive absorption channel.
2. Will Source Naturals Ultra-Mag cause an upset stomach or diarrhea?
Unlike inexpensive supplements containing magnesium oxide—which draw excess water into the intestinal tract and cause frequent loose stools—Ultra-Mag relies on bonded organic amino acid chelates and organic acid salts. These gentle forms are readily assimilated through normal nutrient transport pathways, significantly reducing gastrointestinal distress when taken as directed with food.
3. Why is Vitamin B6 added to this magnesium formula?
Vitamin B6 (pyridoxine) acts as a biochemical escort. Peer-reviewed research from PLoS ONE demonstrates that combining magnesium with Vitamin B6 enhances intracellular mineral uptake and reduces perceived stress by 24% compared to magnesium alone. Vitamin B6 helps carry magnesium ions directly through cell membranes into living tissue.
4. What is the best time of day to take Ultra-Mag?
You can take Ultra-Mag at any time of day, provided you consume it with a meal. However, because magnesium helps calm the central nervous system, relax tight muscle fibers, and promote natural sleep cycles, many users experience the greatest benefit by taking 1 tablet with their evening meal and 1 tablet 30 to 60 minutes before bedtime.
5. How many tablets are in SKU SN0802, and what are the size options?
Product code SN0802 represents the 60-tablet bottle, which provides a full 30-day supply at the recommended dose of 2 tablets per day. Source Naturals also manufactures this exact formula in 120-tablet (60-day supply, SKU SN0803) and 240-tablet (120-day supply, SKU SN0033) bottles.
6. Can I take Ultra-Mag if I take prescription medications?
Magnesium supplements can bind to and decrease the bioavailability of specific prescription drugs, including tetracycline and quinolone antibiotics, bisphosphonates (for bone density), and thyroid medications (levothyroxine). Always space your magnesium intake at least 2 to 3 hours apart from prescription medications, and consult your physician or dispensing pharmacist before starting any new dietary supplement.
7. Is Source Naturals Ultra-Mag suitable for vegetarians and allergen-sensitive diets?
Yes. Source Naturals Ultra-Mag is 100% suitable for vegetarians. It is free from gluten, yeast, dairy, egg, soy, and wheat. It contains no added sugar, artificial colorings, artificial flavorings, or chemical preservatives.
