Source Naturals Glycine Powder (226.8 g / 8 oz) – Pure Free-Form Amino Acid for Restful Sleep and Cellular Defense
Fuel your body at the cellular level with Source Naturals Glycine Powder. Glycine is the smallest and simplest of all 20 amino acids, yet it carries out some of the heaviest lifting in human biology. From calming your nervous system at night to generating whole-body antioxidant shields, glycine is an essential building block your body needs daily.
While your body can manufacture small amounts of glycine on its own, scientific research reveals that natural production often falls short of what we need for optimal tissue repair, collagen synthesis, and metabolic vitality. Source Naturals delivers 100% pure, free-form glycine in an easy-to-mix powder that tastes naturally sweet with zero sugar, zero fillers, and rapid absorption.
✓ 1,000 mg Pure Glycine Per Scoop
✓ Promotes Deep, Restful Sleep
✓ Precursor to Master Antioxidant Glutathione
✓ Zero Fillers, Artificial Colors, or Flavors
Evidence-Based Benefits: How Glycine Supports Your Mind and Body
Below is what peer-reviewed clinical research and biochemical studies demonstrate about dietary glycine supplementation:
1. Deep Sleep and Nighttime Temperature Regulation
Unlike prescription sedatives that force sleep through central nervous system depression, glycine works naturally with your circadian clock. Clinical studies show that glycine gently lowers core body temperature by promoting blood flow to your extremities (hands and feet), which signals to the brain that it is time to transition into restorative slow-wave sleep. Human trials confirmed that taking glycine before bedtime significantly reduced time to fall asleep and cut daytime grogginess without causing morning brain fog.
2. Production of Glutathione – Your Body’s Master Antioxidant
Glutathione is often called the body's chief rust-prevention molecule, neutralizing free radicals and protecting cells from premature aging. Glutathione is constructed from three amino acids: cysteine, glutamic acid, and glycine. Research demonstrates that glycine is frequently the rate-limiting bottleneck. Supplementing with dietary glycine restores optimal glutathione synthesis, defending vital organs against oxidative damage.
3. Joint Comfort, Tendon Strength, and Collagen Synthesis
Collagen is the primary structural protein making up your joints, tendons, ligaments, and skin. Roughly one out of every three amino acids in collagen is glycine. Renowned metabolic research reveals that human internal synthesis falls about 10 grams per day short of fulfilling maximum collagen needs. Pure glycine powder supplies the critical structural units your body demands to rebuild cartilage and retain skin elasticity.
4. Sustained Cellular Energy (ATP) and Muscle Recovery
Glycine acts as an immediate precursor in the synthesis of creatine, an organic compound that replenishes adenosine triphosphate (ATP)—the raw fuel powering muscular contractions and brain cells. For athletes, fitness enthusiasts, and active individuals, glycine helps accelerate recovery from physical exertion and protects lean muscle tissue from breakdown.
Complete Ingredient Listing & Supplement Facts
Source Naturals Glycine Powder contains zero fillers, flow agents, or hidden binders. What is printed on the label is exactly what is in the jar.
Supplement Facts
Serving Size: 1/4 Teaspoon (approx. 1 gram)
Servings Per Container: Approximately 226
Component
Amount Per Serving
% Daily Value
Glycine (Free-Form)
1 g (1,000 mg)
*
* Daily Value (%DV) not established.
Allergen and Dietary Purity Information:
Suitable for Vegetarians and Vegans: Sourced purely without animal derivatives.
Common Allergen-Free: Contains NO yeast, dairy, egg, gluten, corn, soy, or wheat.
Additive-Free: Contains NO added sugar, starch, salt, chemical preservatives, artificial colors, artificial flavors, or fragrances.
How to Use, Taste Profile, and Daily Tips
Suggested Use
Stir 1/4 teaspoon (approx. 1 g) into 4 to 8 ounces of water, fruit juice, herbal tea, or an electrolyte beverage up to two times daily on an empty stomach.
For Sleep Support: Many health practitioners and clinical trials suggest consuming 1 to 3 grams approximately 30 to 60 minutes before going to bed.
Taste Profile & Solubility
The word glycine originates from the Greek word glykys, meaning "sweet." This powder has a pleasant, mild natural sweetness without containing any carbohydrates, sugars, or artificial sweeteners.
It dissolves cleanly within seconds in cold or hot liquids without grit, making it effortless to add to nighttime chamomile tea or morning post-workout shakes.
Important Safety Information, Precautions & Interactions
Your health and safety come first. While glycine is an amino acid naturally present in dietary protein, high-concentration supplementation requires standard clinical precautions:
Pregnancy and Nursing: If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare practitioner prior to use.
Kidney and Liver Health: Individuals with pre-existing renal disease, liver impairment, or anuria (inability to produce urine) should avoid amino acid overload unless directly supervised by a nephrologist or physician.
Known Medication Interactions: Clinical studies indicate that high doses of supplemental glycine may reduce the effectiveness of certain antipsychotic medications, such as clozapine. Always review supplement regimens with your prescribing doctor.
Packaging Security & Storage: Do not use if either tamper-evident seal is broken or missing. Keep tightly sealed in a cool, dry place away from direct sunlight. Keep out of reach of children.
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Peer-Reviewed Clinical References
Our content is backed by published, peer-reviewed medical and scientific literature:
Sleep Quality & Polysomnography: Yamadera W., Inagawa K., Chiba S., Bannai M. (2007). Glycine ingestion improves subjective sleep quality in human volunteers, correlating with polysomnographic changes. Sleep and Biological Rhythms, 5(2): 126–131. DOI: 10.1111/j.1479-8425.2007.00262.x.
Circadian Thermoregulation: Kawai N., Sakai N., Okuro M., et al. (2015). The sleep-promoting and hypothermic effects of glycine are mediated by NMDA receptors in the suprachiasmatic nucleus. Neuropsychopharmacology, 40(6): 1405–1416. DOI: 10.1038/npp.2014.326.
Antioxidant & Glutathione Restoration: Sekhar R.V., McKay S.V., Patel S.G., et al. (2011). Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine. Diabetes Care, 34(1): 162–167. DOI: 10.2337/dc10-1006.
Collagen Biosynthesis Limitations: Meléndez-Hevia E., De Paz-Lugo P., Cornish-Bowden A., Cárdenas M.L. (2009). A weak link in metabolism: the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis. Journal of Biosciences, 34(6): 853–872. DOI: 10.1007/s12038-009-0100-9.
Metabolic & Glucose Modulation: Gannon M.C., Nuttall J.A., Nuttall F.Q. (2002). The effect of glycine on the glucose and insulin response to oral glucose. The American Journal of Clinical Nutrition, 76(6): 1302–1307. DOI: 10.1093/ajcn/76.6.1302.
Frequently Asked Questions (FAQ)
What does Source Naturals Glycine Powder taste like?
Glycine has a pleasant, mild natural sweetness without any bitter chemical aftertaste. It contains zero actual sugar and zero calories from carbohydrates, so you can easily drink it dissolved in plain water or mix it into unsweetened tea.
How does glycine help with sleep without causing morning drowsiness?
Unlike heavy sleeping pills that forcibly sedate your nervous system, glycine assists the body's natural cooling mechanism. It gently lowers core temperature and calms neural excitement in the brain. As a result, you cycle naturally into deep non-REM sleep and wake up refreshed, with clinical trials documenting no morning hangover or grogginess.
Why choose powder instead of capsules or tablets?
Clinical doses for sleep and antioxidant support often range between 1 and 3 grams daily. Achieving this with standard capsules requires swallowing 2 to 6 bulky pills. Powder allows flexible, precise measuring, dissolves instantly, enters the bloodstream quicker, and eliminates capsule binding agents and vegetable coatings.
Can I take glycine with food or should it be on an empty stomach?
For targeted therapeutic benefits like restful sleep or neurotransmitter balance, taking glycine on an empty stomach or with a light beverage is ideal so it does not compete with other dietary amino acids for absorption across the blood-brain barrier. However, taking it with a small meal is acceptable if you have a delicate stomach.
Is Source Naturals Glycine Powder vegan and gluten-free?
Yes. Source Naturals Glycine Powder is 100% suitable for vegetarians and vegans. It is formulated without yeast, dairy, eggs, gluten, corn, soy, wheat, preservatives, or artificial additives.
