How does Guggul Help Control Cholesterol?
|Guggul, Cholesterol and Your Health!||Darrell Miller||02/11/12|
February 11, 2012 07:53 AM
Author: Darrell Miller (email@example.com)
Subject: Guggul, Cholesterol and Your Health!
Guggul is a secretion substance, usually a yellowish rein, of the mukul myrrh tree botanically known as Commiphora mukul. It has been used for centuries now in the Indian Ayurvedic medicine as a remedy for conditions such as osteoarthritis, obesity as well as some skin conditions. Recent studies have also indicated that guggul can also be used to lower the levels of cholesterol mostly by inhibiting cholesterol synthesis and accelerating the removal of the LDL and triglycerides cholesterol. Besides lowering cholesterol and blood fats, guggulipid extracts have been observed to raise the level of HDL cholesterol ,which are good cholesterols, and thus enhancing the health of your heart by shielding it against artherosclerosis vascular disease.
The guggul extract contain a compound that inhibits the functioning of a receptor in the cell known as FXR. This receptor is responsible for regulating the cholesterol in our body by varying the amount of the bile acids in our bodies. Usually, cholesterol in our body is either from synthesis in the liver or from diet. Cholesterol is contained in the bile acids which are made in the liver before being passed to the gall bladder and then to the small intestines. They help in the metabolism of fat in the small intestines before reprocessing and returning to the liver. By preventing the functioning of the FXR receptor implies that more cholesterol becomes excreted. In so doing 14 to 27 percent of LDL cholesterol and 22 to 30 percent of triglycerides cholesterol levels are reduced with use of guggul without need for exercise or diet.
Since guggul is instrumental in hardening of the arteries (artherosclerosis) and maintaining gigh levels of HDL (High-density lipoprotein) it has been seen to be a remedy for male erectile dysfunction and impotence. Further, guggul enhances the function of thyroid gland which is responsible in production of hormones that regulate metabolism. This therefore aids in weight loss by altering the thyroid function to increase production of thyroxine metabolite, triiodothyroxine and T3 which enhances the general body metabolism and by extension enhance burning of fats.
The action of guggul thus creates a balance between low and high cholesterol which may be in our bodies owing to diet, chronic stress, genetic propensity and also lack of exercise. A number of studies have reported that it is a safe and effective remedy to improving and maintaining a ratio of HDL to LDL cholesterols. In addition to maintaining normal ranges of cholesterol levels, it shields you against heart disease and inflammation.
In research, guggul extracts has been observed to clash with CYP3A4 enzyme whose responsibility is to metabolise numerous chemicals in the body. CYP3A4 is also responsible for metabolism of medications and thus guggul use tends to reduce the effectiveness of a number of medications such as diltiazem, propanolol and birth control pills. However, it has been reported that it in fact increases the levels of certain drugs such as statins in the body resulting in an improved effectiveness. Another problem of guggul use is its ability to raise the effectiveness of blood thinners and hence blood clotting becomes a challenge and it results to excessive bleeding. Therefore guggul should be administered only in the event that one is not under medication or the interaction between guggul and the medication is in fact not detrimental.
Have your tried Guggul Today?