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UV Light May Lead Way to New Treatment for MS and Inflammation

old message UV Light May Lead Way to New Treatment for MS and Inflammation Darrell Miller 12/10/16


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Date: December 10, 2016 12:59 PM
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Subject: UV Light May Lead Way to New Treatment for MS and Inflammation





HDACs are molecules driving inflammation and controlling a range of other processes. To get around the problem, researchers at Cornell University designed a molecule that can activate an HDAC blocker using UV light. The team used an existing blocker and covered the part of the drug that interacts with HDAC with an additional molecule. We can control when and where we turn off the HDACs using light.

Key Takeaways:

  • Researchers have found a way to harness inflammation with the help of ultraviolet (UV) light.
  • If this approach can be developed for clinical treatment, it likely will have a large impact on the lives of people with multiple sclerosis and other inflammatory conditions.
  • To get around the problem, researchers at Cornell University designed a molecule that can activate a HDAC blocker using UV light.

"Drugs that block HDACs are being investigated in conditions that include neurodegeneration and cancer, but their role in inflammation is only beginning to be explored."



Reference:

https://www.google.com/url?rct=j&sa=t&url=https://multiplesclerosisnewstoday.com/2016/11/29/uv-light-use-may-lead-to-new-ms-treatment-that-controls-inflammation&ct=ga&cd=CAIyGmZmMDFkMTU2YWMzMmQ5OTU6Y29tOmVuOlVT&usg=AFQjCNGIX8iA2OXj82A4XkA3j9lH0d76wg




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