Modified Citrus Pectin
|Modified Citrus Pectin (MCP)...||Darrell Miller||06/21/05|
June 21, 2005 05:21 PM
Author: Darrell Miller (firstname.lastname@example.org)
Subject: Modified Citrus Pectin (MCP)...
By Isaac Eliaz, M.D.
Modified citrus pectin (MCP) is an essential nutrient for cancer prevention and treatment. It directly attacks cancer, thereby reducing the disease, but also has properties that enhance overall health. A true super nutrient! Let me explain how it can do all this.
Characteristics of Cancer Cells
Cancer cells are different from normal cells in a number of ways. One difference is they way they "look." All cells have a variety of molecules on their surface, which allow them to communicate with each other and their environment:
Cancer cells have odd amounts or unusual molecular markers on their surface, which allow white blood cells to recognize the cells as cancerous and kill them. One type of molecule cancer cells have in excess is galectin-3. Galectin-3 molecules function as "hands" and help cancer spread. First, they are important in reaching out and stimulating growth of new blood vessels; this allows the cancer to obtain the blood flow and nutrients it needs to grow out of control. Second, galectins allow cells that break off from the primary tumor to clump together in the blood stream, enabling them to move to new sites. Third, the galectin hand can grab hold of the new location and complete the metastasis, or spread, of the cancer.
MCP Blocks the Spread and Growth of Cancer Cells
Modified citrus pectin is a natural substance that can bind to galectin molecules and block their spread and growth. Early research on prostate cancer showed that oral administration of MCP to rodents resulted in a dramatic reduction in prostate cancer metastasis to the lungs. More recent research by the same scientists extended MCP protection to breast and colon cancer, and showed that MCP blocks primary tumor growth and formation of new blood vessels.
Successful Clinical Trial
A commercially available form of modified citrus pectin was developed in response to the positive animal studies and tested in men with prostate cancer. A pilot trial using MCP at 15 grams a day and a subsequent phase II trial both showed that MCP slows prostate cancer progression, as evidenced by a reduction in the rate of PSA rise. PSA (prostate-specific antigen) is a protein made by the prostate gland; elevated PSA blood levels may indicate prostate cancer. The phase II trial, published in Prostate Cancer and Prostatic Diseases (Dec 2003), involved men who at first experienced successful primary conventional treatment; subsequently their PSA again began to climb, representing cancer recurrence. Seventy percent of these men showed a significant reduction in the rise of their PSA climb! Because of the mechanism of action, it is expected people with other cancers (leukemia, breast, colon, lung, nasopharyngeal, brain, lymphoma, melanoma and others that express galectin molecules) also would benefit from MCP.
MCP Chelates and Removes Toxic Metals
Heavy metals, in conjunction with environmental toxins and xenoestrogens, constitute a dangerous insult to the body through DNA damage, hormonal modulation, immune suppression, oxidative stress, and hyper inflammation. The metal chelation properties of MCP (Eliaz, U.S. patent #6,462,029) have been confirmed in a recent pilot trial. In healthy individuals, MCP increased urinary excretion of the toxic metals mercury, cadmium, arsenic and lead. In addition, longterm administration of MCP has been shown to reduce the body burden of heavy metals such as mercury, arsenic, lead, and nickel. MCP's ability to remove heavy metals and environmental toxins on an ongoing basis may significantly benefit people with cancer and other diseases involving immune dysfunction.
Clinically Validated MCP
Only one form of MCP has been validated in human clinical trials. This is important since no other MCP on the market matches the chemical specifications of the clinically validated product. If the molecular weight of MCP is too high it can't be absorbed into the bloodstream. If it is too low it won't effectively block galectin sites. Another property, the degree of esterification, must be below 5% for optimal binding. The most effective specifications were defined by cell culture studies and remain a trade secret. If you want the effects seen in the clinical studies, you must take the preparation used in those studies, at the recommended dose of 15grams/day.
The Use of Modified Citrus Pectin
MCP Application Use (Take on an empty stomach) Active Cancer 15 grams/day (5 grams, three times a day) Biopsy 15 grams/day (5 grams, three times a day) Take one week before procedure and two weeks after. Heavy Metal Chelation High body burden levels: 15 grams/day (5 grams, three times a day) Lower levels: 15 grams/day for 5 days a month, 5 grams/day the rest of the month Cancer Prevention 5 grams/day ongoing
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