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Scientists discover potent trigger of inflammatory disease

old message Scientists discover potent trigger of inflammatory disease Darrell Miller 02/25/17


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Date: February 25, 2017 12:59 PM
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Subject: Scientists discover potent trigger of inflammatory disease





Scientists have discovered a potent trigger of inflammatory disease. The inflammatory molecule that is released by dying cells, triggers inflammation during necroptosis. The discovery could actually lead to new and existing medicines that target the molecule being investigated as a way of treating inflammatory diseases. Psoriasis and inflammatory bowel disease are two such diseases.

Key Takeaways:

  • Institute scientists have revealed that a potent inflammatory molecule released by dying cells triggers inflammation during necroptosis.
  • The discovery challenged a long-standing dogma that inflammation triggered by necroptosis was a byproduct of dead cell debris.
  • Research suggests that existing drugs that block IL-1 might be useful in treating these diseases.

"Necroptosis is important for protecting us against infections, by sacrificing infected or diseased cells 'for the greater good'."



Reference:

https://www.google.com/url?rct=j&sa=t&url=//www.news-medical.net/news/20170222/Scientistsc2a0discover-potent-trigger-of-inflammatoryc2a0disease.aspx&ct=ga&cd=CAIyGmZmMDFkMTU2YWMzMmQ5OTU6Y29tOmVuOlVT&usg=AFQjCNHKtdb4DV2ys8xU5tay38yiqVa_VA




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