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Can Celadrin Help Joint Pain? Darrell Miller 3/5/14
The Skinny on Fats - Omega-3, Omega-6, Omega-7, Omega-9 Darrell Miller 10/4/06
- US Center for Disease Control, 2005 Darrell Miller 12/7/05
Celadrin and MSM Fact Sheet Darrell Miller 12/7/05
Celadrin - Benefits Darrell Miller 7/27/05
Celadrin® Complex with Glucosamine. Darrell Miller 5/12/05



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Can Celadrin Help Joint Pain?
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Date: March 05, 2014 08:08 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Celadrin Help Joint Pain?

Celadrin

In clinical studies, Celadrin cream application has been demonstrated to lessen joint torment in less than 30 minutes. This quite viable, all-common mitigating medication holds a protected mix of specific greasy acids and some menthol's to help reduce torment in the joints, advertise joint flexibility and grease and to help smooth sore muscles.

How can it function?

A long time involving usage in addition to strenuous action can certainly reduce the mobility of your joint parts in addition to deterioration your water that ones your joint parts via pain, ultimately producing osteoarthritis. Celadrin gives remedy in addition to rejuvenation of those joint parts. The item functions by lubricating your mobile walls, so improving your extra padding power involving joint parts in addition to bones. Fat have also been proven to avoid your routine involving redness, making an effort to relieve pain within the joint parts in addition to muscular tissues. When you suffer from muscle mass in addition to joint, Celadrin ointment affords the relief you have to make it through your worktime. Analyzed from prime educational facilities in addition to major medical stores, Celadrin ointment gives relief in order to aching muscular tissues in addition to joint parts.

It provides lubrication in addition to works just like a "cushion" among joint parts in addition to cartilage. Rigid joint parts in addition to pain are generally as a result of bad lubrication. Celadrin Product gives remedy in order to fatigued, aching muscular tissues in addition to joint parts. The majority of people think outcomes inside a half-hour.

Scientifically Efficient Joint pain Pain relief

The results involving human being specialized medical trial offers assist the effectiveness of Celadrin ointment. In a double-blind placebo-controlled trial run released within the Journal involving Rheumatology, forty five participants along with uncomfortable knee joint parts - ingested both Celadrin Mutual Proper care Pain relief or even a placebo ointment to put on topically double every day intended for 1 month. Members have been evaluated on several orthopedic procedures involving development. At the conclusion in the examine, your analysts known that the Celadrin had been a simple yet effective therapy intended for enhancing knee mobility, chance to ascend/descend stairways, chance to surge via seated, go in addition to have a seat, in addition to unilateral sense of balance. No changes have been welcomed in your placebo class. Another examine involving 28 people who have arthritis in the knee additionally revealed major improvements throughout knee function, range of motion in addition to pain decrease in a matter of a single week involving utilizing Celadrin ointment.



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The Skinny on Fats - Omega-3, Omega-6, Omega-7, Omega-9
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Date: October 04, 2006 04:53 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Skinny on Fats - Omega-3, Omega-6, Omega-7, Omega-9

Health experts keep changing the storey on fats. First we were told that polyunsaturated fats were better than saturated fats. Then it was discovered that refined polyunsaturates were favorite targets for free radical attack. Next, monounsaturated fats took center stage and have remained in the spotlight ever since. The Mediterranean Diet, with its high intake of olive and other oils high in monounsaturates, offers several important safeguards against cardiovascular disease, cancer and overall mortality. (Laino, de Largeril, Kokkinos, Trichopoulou). While monounsaturated fats are important for maintaining optimum health and smooth supple skin, it’s the kind of fatty acids and antioxidants they contain that make up the real story.

Designer Oils

Dark green unrefined “extra Virgin” olive oil has a delightful full bodied flavor due to its natural antioxidants. Not only are the oils of various olive cultivars distinctive, they all help fight arterial plaque buildup. (Visioli) Olive oil has a long history in Europe as both food and medicine, and carbon dating of seeds found in spain have shown that the use of olive oil dates back 8,000 years. Gourmet chefs usually prefer particular oils for various uses in making dressing, marinades, and sauces for dipping. Olive orchards have now achieved a status second only to that of vineyards.

Macadamia nut oil is another designer oil that is fast gaining a reputation among chefs and health experts. The nuts originated in Australia where they were staples in the diets of the Aborigines. In 1881, they were introduced in Hawaii and in the 20th century, made their way to California where several cultivars are now grown. Like olive oil, macadamia nut oil is rich in antioxidants and contains the highest levels, greater than 80 percent monounsaturates, primarily polmitoleic (omega-7) than other oils. (Hiraoka-Yamamoto)

Macadamia nut oil products found in mass market are typically refined, with many of the antioxidants removed. The highest levels of antioxidants in macadamia nuts are found in the shells. During cold processing, some of these antioxidants leech into the oil, increasing its antioxidant potential. (Quinn) unrefined and organic oils have a golden color, pleasing nutty aroma and buttery flavor. Scientists have found that macadamia nut oil lowers, LDL cholesterol and triglycerides, and may help prevent stroke. (Yamori, Colquhoun) It is delightful on vegetables, in soups, on popcorn, and as a replacement for butter in baking.

EFA Supplements

The essential oils (Fish oils, flaxseed, GLA, DHA), which are available as liquid and packaged in black bottles, must be stored in the Refrigerator even when they have not been opened. You cannot heat or cook with them. Essential fatty acid supplements are convenient to take and have specific therapeutic value.

Cardiovascular and Nerves – Consumers have been advised to eat more fish rich in Omega-3 to reduce their risk of cardiobascular disease. However, experts worry that eating several servings of fish each week may not be safe especially during pregnancy, dursing or trying to conceive. Instead they recommend fish oil supplements such as Omega-3 from Algae , Fish oil, and Omega-6 Evening Primrose and Borage oils.

Pain Relief – A blend of cetylated fatty acids including myristate, myristoleate, laurate, oleate, palmitate and palmitoleate appear to be effective in reducing inflammation and pain in arthritis and other inflammatory conditions. (Vanderhaeghe) In a San Diego California study of sixty-four patients with osteoarthritis, an oral preparation of cetylated fatty acids known as Celadrin significantly improved range of motion and flexibility. (Hesslink)

Two other studies of osteoarthritis patients at the University of Connecticut, using a topical preparation of Celadrin, showed significantly greater knee stability, improvement in stair climbing ability, balance and strength, and reduction of pain. (Kraemer)

Animal studies at the University of Minnesota have shown that cetylated fatty acids administered either topically or orally are well tolerated and rapidly dispersed throughout the body. (Gallaher) Doses for the oral form are 1500mg three times a day. The topical cream is applied two to four times a day.



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- US Center for Disease Control, 2005
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Date: December 07, 2005 01:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: - US Center for Disease Control, 2005

“Forty-three million Americans report that a doctor told them they have arthritis or other rheumatic conditions. Another 23 million people have chronic joint symptoms but have not been diagnosed with arthritis. Arthritis is the leading cause of disability in the United States, limiting the activities of more than 16 million adults.” - US Center for Disease Control, 2005

This is of alarming concern, especially if you’re one of the nearly 60 million US adults who live with a joint disorder. Clearly, you don’t need to be reminded of what a struggle it can be. Mundane tasks become major, and major tasks become painful reminders of what life was like when your joints were strong and seemingly indestructible. Many sufferers lose hope, while others hopelessly lose out on so many of life’s activities.

Over the past ten years, notable advances in the nutritional sciences have paved the path for landmark products such as Glucosamine, SAMe, Chondroitin, MSM, and others. As a result, millions have found relief in these products and continue to use them in their quest towards healthy mobility. Fortunately, the science behind these popular joint support supplements has done nothing but steadily improve. Celadrin® is perhaps the most convincing proof to date. Let’s examine.

In short, Celadrin® is novel blend of acetylated fatty acids, esters and other synergistic agents that enhance cell membranes throughout the body, resulting in greater mobility and more normalized joint function. The extremely high user success rate and virtually complete absence of side effects has helped Celadrin® rise to the rank of joint support extraordinaire. Yes, this is a bold statement. However, just one look at the supporting research is enough to convince even the most skeptical critics of what a true breakthrough it is. Celadrin®’s ability to provide fast, cumulative relief continues to be evidenced by extensive clinical research, as well as a steady flow of eye-opening human trials.

Unlike popular non-steroidal anti-inflammatory drugs (NSAIDS) that simply mask joint discomfort, Celadrin® targets the source by enhancing cell membranes and restoring the vital fluids that cushion bones and joints. Ultimately, this is what makes it possible to enjoy a free range of motion without the bone-on-bone grinding that limits so many from their daily activities. Working in much the same manner that other fatty acids do, Celadrin®’s patented blend of esterified fatty acids spark positive changes at the cellular level. As this occurs, cell membranes become more responsive and less prone to articular cartilage deterioration.

“How long do I need to take it?”

Not only does it work well, studies continue to illustrate Celadrin®’s ability to work fast. This can be attributed to how easily absorbed the active ingredients are. In 2005, a University-led, placebo-controlled study examined 42 patients who struggled with knees that were…let’s just say less than fully functional. After just 30 minutes, 100% of the subjects treated with a topical form of Celadrin® reported significant improvement in joint mobility and support. Even more impressive, each participant demonstrated continuous and restorative benefits over the course of the entire 30 day study.

“How do I use Celadrin®?”

One of the most appealing elements of Celadrin® is the flexibility that users have when it comes to taking charge of their joint health. It is available in both oral and topical forms, and each is equally effective. Some users have reported greater results by supplementing the oral form while applying the topical lotion directly to the target areas in question. Still, no two people are alike. Accordingly, the severity and nature of each individual concern will vary from person to person. Therefore, it can be wise to determine which application works best for your particular situation.

“What if I don’t have joint problems?” For openers, you’re very fortunate. If your joints are strong and fluid, Celadrin® is one of the most effortless ways to keep them that way! Cartilage breakdown is gradual, and occurs over a long, delayed, unsuspecting period of time. In many cases, there is very little warning that your knee or shoulder is about to become part of a frightening and growing statistic. Your joints may feel fine today, but you’d be amazed at how fast that can change. Think of Celadrin® as Cartilage Insurance. You may not see an immediate need to support them right now, but if they do give out, you’ll sincerely wish you had.

“What should I look for in a Celadrin® product?”

As with every dietary supplement and joint-support product, you should always look for a quality formula from a trusted, well-established manufacturer with a history of producing quality products. NOW® Celadrin® products are scientifically formulated, tested for safety and potency and guaranteed to be of superior quality. Each full serving contains 1.5 g (1500 mg) of Celadrin® along with 300 mg of MSM for additional support. NOW® Celadrin® Liposome Lotion contains 7.5 % Celadrin® along with 1.25% USP Pharmaceutical grade natural Menthol. Both are now available at fine independent health food retailers nationwide.* credits: Jayson Kroner [mailto:jayson.kroner@nowfoods.com]

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Celadrin and MSM Fact Sheet
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Date: December 07, 2005 01:24 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Celadrin and MSM Fact Sheet

Celadrin and MSM Fact Sheet

Neil E. Levin, CCN, DANLA Certified Clinical Nutritionist, Diplomate in Advanced Nutritional Laboratory Assessment Revised 11/10/05

LIKELY USERS: People lacking flexibility or mobility; People wanting temporary control of aches and pains; People wanting to reduce pro-inflammatory body chemicals. KEY INGREDIENT(S): Celadrin® powder 500 mg. Provides 350 mg. of actual EFAC (esterified fatty acid carbons). This is a proprietary blend of Esterified Fatty Acid Carbons of Myristate, Myristoleate, Laurate, Oleate, Palmitate and Palmitoleate in a base of tapioca and silica.

MSM 100 mg.

MAIN PRODUCT FEATURES: Celadrin® is an all-natural proprietary matrix of esterified (cetylated) fatty acid carbons (EFAC) derived from tallow of USA-raised cattle. This product is developed through a proprietary process of esterifying oil & has been clinically tested. Celadrin promotes joint health by improving flexibility, pain management and mobility. The myristoleic acids and the cetylated forms may alter the 5-LOX enzyme and change the leukotriene production, inhibiting inflammatory compounds.

Celadrin® may offer some noticeable benefits faster than other substances, like glucosamine and chondroitin. Though it is not a substitute for these important tissue-building nutrients. ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: MSM has synergistic abilities to reduce certain substances in the body which may affect the inflammatory process.

Contains Cetyl Myristoleate (CM, CMO), but in a patented blend of other fatty acid carbons. This product (Celadrin ®) has its own clinical studies showing safety and efficacy.

Also will be available in a softgel of the same potency (350 mg. of EFAC) as of December 2005 (product 3017, 90 softgels)

SERVING SIZE & HOW TO TAKE IT: Three capsules a day, preferably with meals.

POSSIBLE SYNERGISTS: Glucosamine, Chondroitin, MSM, Joint Support Products, Manganese, Vitamin C, other Antioxidants

CAUTIONS: None.

SPECIFIC: None

GENERAL: Pregnant and lactating women, and people using prescription drugs, should consult their physician before taking any dietary supplement.

This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients.

When taking any new dietary supplement, use common sense and cautiously increase to the full-recommended dose over time, looking for possible side effects. Repeat this process for each new supplement that you start to use.

REFERENCES: 1. J Rheumatol. 2002 Aug;29(8):1708-12. Cetylated Fatty Acids Improve Knee Function in Patients with Osteoarthritis. Hesslink R Jr, Armstrong D 3rd, Nagendran MV, Sreevatsan S, Barathur R.
2. Anticancer Res. 2003 Jan-Feb;23(1A):453-8. Aspirin and methylsulfonylmethane (MSM): A Search for Common Mechanisms, with Implications for Cancer Prevention. Ebisuzaki K.
3. J Altern Complement Med. 2002 Apr;8(2):167-73. A Multicentered, Open-Label Trial on the Safety and Efficacy of Methylsulfonylmethane in the Treatment of Seasonal Allergic Rhinitis. Barrager E, Veltmann JR Jr, Schauss AG, Schiller RN. (allergy related inflammation)



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Celadrin - Benefits
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Date: July 27, 2005 11:09 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Celadrin - Benefits

Benefits

Increased Range of Motion in Joints*

Research has shown that Celadrin can have an impact on improving the range of motion in joints. A placebo-controlled trial conducted in 2002 showed that those individuals taking a complex containing Celadrin for 2 months had a significant improvement in knee flexion (ability to bend the knee) over those taking a placebo.1 Another study conducted on Celadrin published in 2004 concluded that treatment “significantly increased physical performance (as measured by a variety of orthopedic tests)” in patients with compromised knee mobility. The study found that the subjects given Celadrin showed improvement in their ability to climb stairs, rise from a chair and walk, along with an improved sense of balance, strength and endurance.3

Maintains Joint Comfort*

The anti-inflammatory actions of Celadrin have been demonstrated by one double-blind, placebo controlled trial that showed Celadrin, when taken orally at recommended intake levels, decreased pain scores and increased walking distance compared to the group receiving placebo. The authors theorize that Celadrin may work by down-regulating the effect of certain precursors of the body’s inflammatory response.1

Safety

Suggested Adult Use: One capsule three times daily, with or without food.

Scientific References
1. Hesslink R Jr., et al. Cetylated fatty acids improve knee function in patients with osteoarthritis. J Rheumatology 2002;8:1708-1712.

2. Anonymous. Monograph: Glucosamine sulfate. Alt Med Review 1999;4:3;193-195.

3. Kraemer WJ, et al. Effect of a cetylated fatty acid topical cream on functional mobility and quality of life of patients with osteoarthritis. J Rheumatology 2004;4:767-74.

4. Crolle G, D'Este E. Glucosamine sulphate for the management of arthrosis: a controlled clinical evaluation. Curr Med Res Opin 1980;7:104-109.

5. Rovati LC. Clinical research in osteoarthritis: design and results of short-term and long-term trials with disease modifying drugs. Int J Tissue React 1992;14:243-51. Acting as a biochemical "super-thiamin," it does this through several different cellular mechanisms, as discussed below.

6. Bassleer C, et al. Stimulation of proteoglycan production by glucosamine sulfate in chondrocytes isolated from human osteoarthritic articular cartilage in vitro. Osteoarthritis and Cartilage 1998;6:427-434. Med. 2002 Oct 14;162(18):2113-23.

7. Reginster JY, et al. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomized, placebo-controlled clinical trial. Lancet 2001;357:251-56.

8. Macario, J. T., Rivera, I.C. Bignamini, A.A. Oral glucosamine sulphate in the management of arthrosis: report on a multi-centre open investigation in Portugal. Pharmatherpeutica 1982; 3(3):157-68. 9. Kraemer WJ, et al. Effect of acetylated fatty acid topical cream on functional mobility and quality of life of patients with osteoarthritis. J Rheumatol.2004 Apr;31(4):767-74. 10. Kraemer WJ,et al. Acetylated fatty acid topical cream with menthol reduces pain and improves functional performance in individuals with arthritis. J Strength Cond Res.2005 May;19(2):475-80.



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Celadrin® Complex with Glucosamine.
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Date: May 12, 2005 09:31 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Celadrin® Complex with Glucosamine.

DOCTOR’S BEST INTRODUCES Celadrin® Complex with Glucosamine. A potent new joint soothing formula now available from Doctor’s Best!

SAN CLEMENTE, Calif., January 2005 –– Doctor’s Best has introduced Celadrin ® Complex with Glucosamine into its dietary supplement line. Ken Halvorsrude, president of Doctor’s Best, made the announcement.

Celadrin ® is a special blend of fatty acids that have been shown in double-blind, placebo-controlled trials to support joints and improve mobility. Fatty acids have been shown to induce changes in cell membranes and their responsiveness to immune factors, which often result in painful side effects. The special fatty acids found in Celadrin ® have also been shown to control and reduce the production of immune factors which can have a negative impact on the body.

Current studies show that Celadrin ® works much more effectively than the essential fatty acids, such as EPA and DHA from fish oils,” Halvorsrude says, “plus it provides continuous lubrication to joints, and helps prevent tissue stiffening.”

The results of a double-blind, placebo-controlled trial found that Celadrin ®, when taken orally, helped improve joint and mobility problems. Sixty-four participants between the ages of 37 to 77 were given Celadrin ® capsules. They were evaluated at the beginning, at 30 days and at the end of the 68 day study. When compared to the placebo group, Celadrin ® participants had more flexibility, and were able to walk longer distances than the placebo group.

Glucosamine, which has been shown in clinical studies to increase range of motion, also assists in rebuilding cartilage. When used in combination with Celadrin ®, glucosamine works even more efficiently at building cartilage and providing rapid joint cushioning.

“For these reasons, “ Halvorsrude says, “we feel that Celadrin® Complex with Glucosamine will be able to bring relief to many people suffering with joint problems.”

Founded in 1990 by supplement industry veteran Halvorsrude and a wholistic physician, San Clemente-based Doctor’s Best, Inc. manufactures and distributes dietary supplements throughout the U.S. and overseas. Doctor’s Best is known for high-quality products that are based on sound research in the field of nutritional science. For more information:

Celadrin Complex with Glucosamine


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