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Astragalus Fact Sheet
Date:
December 07, 2005 01:15 PM
Astragalus Fact SheetNeil E. Levin, CCN, DANLA 02/10/05LIKELY USERS: Everyone seeking a healthy immune system; Those lacking energy KEY INGREDIENTS: Astragalus Root Extract Powder 70% polysaccharides (200 mg) MAIN PRODUCT FEATURES: A Chinese “tonic herb” used in Traditional Chinese Medicine for night sweats, diarrhea and lack of energy. Tonic herbs are often known as “adaptogens”, helping the body adapt to stresses and modulating immune system responses. Some reports credit Astragalus with shortening colds and strengthening the heart.Astragalus additionally contains triterpene glycosides, also known as astragalosides. ADDITIONAL PRODUCT INFORMATION: Vegetarian formula.May be useful to maintain the patient’s immunity in dialysis patients, those with liver problems and those who have suffered from strokes, according to Chinese studies (not as a treatment for those conditions!). SERVING SIZE & HOW TO TAKE IT: For everyday use take one to five caps per day, either with meals or on an empty stomach. COMPLEMENTARY PRODUCTS: Immune Renew, Inositol Hexaphosphate (IP-6), I3C, Pometrol, mixed carotenoids and other antioxidants. CAUTIONS: Pregnant & lactating women, children and people using prescription drugs should consult their physician before taking any dietary supplement. Do not take with AIDS drugs or if you have an autoimmune disease, though there is some (not enough) evidence that Astragalus may balance immune function for at least one autoimmune disorder. This information is based on my own knowledge and these references, but should not be used as diagnosis, prescription or as specific product claims. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
REFERENCES: 1. Ooi VE, Liu F. Immunomodulation and anti-cancer activity of polysaccharide-protein complexes. Curr Med Chem. 2000 Jul;7(7):715-29.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=984) Immune Renew Fact Sheet
Date:
December 07, 2005 01:07 PM
Immune Renew Fact Sheet Neil E. Levin, CCN, DANLA 02/10/05 LIKELY USERS: Everyone seeking a healthy immune system; People on low carb diets or non-whole grain diets that are lacking dietary beta-glucans KEY INGREDIENTS: Astragalus Root Extract Powder 70% polysaccharides (200 mg). Proprietary blend of 8 organically grown “medicinal mushrooms” (200 mg) MAIN PRODUCT FEATURES: Vegetarian formula. Polysaccharides in these US-grown mushrooms grown on organic brown rice include 1,3 Beta-glucans and terpenoids. Beta-glucans may stimulate the immune system in different ways. Triterpenoids may act as mild anticoagulants. Each mushroom may have a different effect; for example, one may stimulate T-cells and another Natural Killer cells, aiding in immune defense. Mushrooms have reported beneficial effects on liver health and promoting normal cell growth. ADDITIONAL PRODUCT INFORMATION: Some extracts from these kinds of mushrooms have been used medicinally in Japan and China. The mushrooms include Turkey Tail, Sun Mushrooms, Maitake, Cordyceps, Phellinus, Lion’s Mane, Reishi and Shiitake. The astragalus extract also contains naturally occurring astragalosides. Mushrooms may help maintain normal cholesterol and triglyceride levels SERVING SIZE & HOW TO TAKE IT: For everyday use take one or two caps per day, either with meals or on an empty stomach. COMPLEMENTARY PRODUCTS: Vitamin C to break down beta-glucan structures for better absorption, Inositol Hexaphosphate (IP-6), I3C, Pometrol, mixed carotenoids and antioxidants CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. Do not take with AIDS drugs or if you have an autoimmune disease. Use with caution if using anticoagulants or blood pressure medication, as these mushrooms may have mildly synergistic effects to those drugs. Do not use if you have mold or mushroom allergies (or any sensitivities to mushrooms, cheese, etc.), which can potentially result in hives, rashes, breathing difficulties (including dry mouth or throat), stomach distress, diarrhea, or any other unusual side effect. This information is based on my own knowledge and these references, but should not be used as diagnosis, prescription or as specific product claims. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES:
1. Hobbs C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=983) Botanical Arsenal - Plants can help our bodies fight off cancer's deadly ...
Date:
June 13, 2005 10:31 AM
Botanical Arsenal by Fred Thomas Energy Times, May 3, 1999 The complexities surrounding the various types of cancer stem from the variety of ways in which these diseases can wreak their havoc. Luckily, the equally complex world of plants contains novel compounds that can help our bodies fight off cancer's deadly progress. Research Expands Research into these botanical compounds is mushrooming. An example: The mighty maitake, a fungus with flair, alternately known as the king (it can grow as large as a basketball, worth its weight in silver to the ancient Japanese); the prince; the Hen of the Woods (it sticks out of from trees when it grows in the wild); and the dancing mushroom to those who leaped for joy when they found one growing in its native northeastern Japan. Researchers today dub it with a new moniker: Herbal Heavyweight. Mushroom with Potential The maitake, with such other medicinal mushrooms as shiitake and reishi, historically has been eaten to promote general well-being and vitality. In the modern lab, however, scientists focus on the potent immune enhancing powers of maitake, which spotlight its cancer fighting potential. Twenty years ago, maitake, Grifola frondosa, was an obscure, largely unavailable mushroom. A series of significant Japanese studies then catapulted it into prominence-and popularity. Maitake Magic Hiroaki Nanba, PhD, of the department of immunology at Kobe Women's College of Pharmacy on Kobe, Japan, and a leading international researcher on maitake, conducted the preliminary tests on the mushroom, demonstrating that it stimulates immune function and inhibits tumor growth. In 1986, Dr. Nanba fed powdered maitake to mice injected with tumor cells; 86.3% displayed inhibited tumor growth. Dr. Nanba and his colleagues went on to run additional mouse tests, finally reporting that this potent mushroom "directly activates various effector cells (macrophages, natural killer cells, killer T-cells, etc.) to attack tumor cells." From then, maitake mushrooms were headed to fame as cancer ninjas. Stoking The Immune Engine Like other mushrooms, maitake is rich in complex polysaccharides, immunomodulators that successive tests after Dr. Nanba's have shown to be effective in cancer and AIDS treatment. The polysaccharides in maitake have a unique structure, rendering them some of the most powerful to be studied (Chem Pharm Bull 1987:35:1162-8). What makes maitake a particularly hot property is beta-D-glucan, its primary polysaccharide. Studies show that the body absorbs it readily, at which point it effectively stimulates interleukin-1, natural killer cells and macrophages, anti-tumor warriors that battle solid cancers (Chemotherapy 1990;38:790-6; also International Conference on AIDS, Amsterdam, 1992). Effective And Safe In addition to lab tests, trials on people have shown that maitake may offer powerful therapy against liver and stomach cancer (studies in China), breast and colon cancer (US research) and Kaposi's Sarcoma, the virulent cancer attacking AIDS sufferers. Importantly, studies show that no side effects or interactions accompany maitake's efficacy. Maitake fortunately has won the interest and enthusiasm of the scientific community. Currently, researchers at the Cancer Treatment Centers of America, headed by Denis Miller, MD, are completing an exhaustive test of the anticancer and immunostimulatory actions of maitake on folks with advanced colorectal cancer. These investigators hypothesize that the polysaccharide beta-glucans derived from the fruitbody of maitake fight tumors and boost immune function. "Though it cannot be said that maitake ...[is] the cancer cure," said Dr. Nanba in his closing remarks at the Adjuvant Nutrition in Cancer Treatment Symposium in Tampa, Florida, in October 1995, "one can safely say that they do maintain the quality of life of patients and improve the immune system, resulting in the possible remission of cancer cells with no side effects." More Bodily Benefits Maitake maven Dr. Nanba also has tested-with strongly positive results-the effect of maitake on blood glucose, insulin and triglycerides in mice, whose levels of all three substances declined when they were fed the mushroom (H. Nanba working paper, Anti-Diabetic Activity by Maitake Mushroom, 1994). With colleagues, Dr. Nanba showed that maitake lowered blood pressure in hypertensive rats (Chem. Phann. Bu//36:1000-1006,1988). Other studies suggest it may accelerate weight loss. This admirable adaptogen (meaning it helps the body adapt to stress and normalize its functions) is water soluble and may be eaten in food or taken as a supplement. Vitamin C is believed to intensify maitake's beta-glucans and enhance their absorption. Tea Time It's not just what you eat that may help protect against cancer, but what you drink as well. Research from China and Japan, where tea is the everyday drink and rates of several cancers like breast and prostate are lower, may persuade you to turn over a new leaf in your own beverage choice. One of the first studies to spark interest in tea came from Shanghai (Journal of the National Cancer Institute, June 1, 1994), where people who drank two to three cups a day were found to have about a 60% reduction in the risk of cancer of the esophagus. The reason: tea leaves contain compounds called polyphenols, potent antioxidants. In fact, in tests at the University of Kansas, three of these, known as catechins, far outshone the common antioxidant vitamins C and E. Clinical trials are just starting, but early results are encouraging. A team of Chinese scientists reported that in a third of people with precancerous mouth sores who drank three cups of a mixture of green and black tea the lesions shrank significantly. Researchers at the Saitama Cancer Center in Japan found that green tea seems to improve the prognosis of breast cancer. They followed a group of women with early-stage tumors for seven years. Those who drank more than five cups of green tea a day were only half as likely to suffer a recurrence as patients who consumed fewer than four cups a day. Lung Help And at the University of Indiana, toxicologist James Klaunig found that the lungs of cigarette smokers who drank the equivalent of six cups of tea a day suffered 40 to 50 percent less damage from the toxins in smoke, potentially lowering their risk of lung cancer and other pulmonary problems. Simultaneously, research from Purdue University suggests tea's cancer-discouraging powers go beyond being an antioxidant. Scientists Dorothy and D. James Morre showed that a tea catechin dubbed EGCG inhibits a growth-promoting enzyme on the surface of many cancer cells-happily without affecting normal cells. And researchers at the Ohio State University College of Medicine found that EGCG counteracted another enzyme, urokinase, that helps cancer cells spread. To top it off, Mayo Clinic scientists recently showed that EGCG prompted prostate cancer cells to commit suicide (Cancer Letters, Aug. 14, 1998). Tea Research So far, most tea research has focused on green tea, and investigators agree it's more potent than the black tea most Americans favor. But because both kinds come from the same plant, Camellia sinensis (it's the processing that makes the difference as black tea is fermented, green tea isn't) both contain cancer-fighting polyphenols, just in different quantities. As long as the tea you drink (even decaffeinated) is fresh brewed, it's likely to provide some benefit; powdered and prepared teas probably don't. And adding milk may dilute the effect. Astragalus Against Tumors Astragalus, an herb commonly used in Asia to boost stamina, has impressed western doctors for its potential for helping people cope with chemotherapy. As John Diamon, MD, W. Lee Cowden, MD and Burton Goldberg point out in the Definitive Guide to Cancer (Future Medicine), "Astragalus appears to protect the liver against the harmful toxic effects of chemotherapy and may be effective in treating terminally ill liver cancer patients." (They cite a study in the Jrnl of Ethnopharmacology 1990, 30:145-149.) In addition, they point out, research in Japan supports using a ginseng-astragalus combination to improve the function of natural killer (NK) cells which can boost immunity (Japanese Jrnl of Allergy, 37:2, 1998, 107-114). Other studies confirm astragalus' potential in fighting off cancer. Research at the General Hospital of PLA, Beijing, showed that flavonoids (pigments) in astragalus could help protect cell membranes from oxidative damage caused by ultraviolet exposure (Chung Kuo Chung Yao Tsa Chih, 21(12):746-8; 1996 Dec). A study of laboratory animals at Cunma University in Maebashi, Japan, found that Astragalus could help preserve immune function against the harmful side effects of chemotherapy (Chung Kuo Chung Hsi I Chieh Ho Tsa Chih, 15(2):101-3, 1995 Feb). Garlic Benefits Like a flame attracting moths, garlic bulbs have irresistibly drawn the attention of medical researchers. A study at Aarhus University, Denmark, found that skin cells in laboratory dishes treated with garlic supplements lived longer, healthier lives than untreated cells (Jrnl Ethnopharm, 1994. 43:125-133). Meanwhile, a long list of research demonstrates that garlic's phytochemicals may fight tumors and reduce the carcinogenicity of the pollutants and chemicals that assault us daily. A study in China reported in the American Journal of Chinese Medicine showed that garlic helped slow tumors in lab animals (1983, 11:69-73). Another study in the Journal of Nutrition found that compounds in garlic could "suppress the growth of human colon tumor cells" (126, 1355-1361). Added to those benefits, Robert A. Nagourney, MD, reports in the Journal of Medicinal Food (1:1, 1998, 13-28), garlic may "modify the carcinogenicity of foodstuffs." In other words, studies show that garlic can make chemicals in foods like pork less likely to cause your cells to become cancerous. (Ind J Physiol Pharmacol, 39:347-353). DNA Protection DNA, the stuff that genes are made of, face constant threats from free radicals, caustic molecules that can alter cellular structure and possibly cause genetic mutations that lead to cancer. But research into what are called oligomeric proanthocyanidins (OPC), flavonoids (pigments) derived from fruits vegetables, grape seed extract and the bark of maritime pine trees shows that OPC may be able to shield DNA from injury. In particular, studies of a grape seed extract called Activin have demonstrated this substance can help liver cell DNA escape a destructive process called peroxidation (FASEB, 11:3, 2/28/97). In these experiments, Activin demonstrated the ability to inhibit the growth of tumor cells as well as slow the replication enzymes of HIV viruses. This protective ability proved to be more potent than that of vitamin C, beta carotene and vitamin E. Future Promise What does the future promise to reveal? Scientists believe that many unexamined plants probably contain undiscovered phytochemicals that hold great potential for helping us fight the cancer epidemic. Certainly, if the next few years produce as many results as the past decade, the next millennium will witness a long line of cancer-prevention discoveries. Before long, you should be able to take advantage of these potent substances. As you gulp your garlic, tip your tea cup, mull your maitake, acquire Activin and await your astragalus, you may meditate on what may soon be added to our growing anti-cancer arsenal. Undoubtedly, scientists with a botanical bent will be uncovering more coveted anti-cancer secrets before too long.
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