Search Term: " Chondroitin "
The Versatile Benefits of BioCell Collagen®
Date:
September 14, 2022 11:56 AM
As we age, it's not only important to maintain our health, but also our appearance. Joints can begin to creak, skin can become dry and saggy, and generally we can start to feel and look a lot older than we actually are. But did you know that there is a supplement that can help with all of those things? BioCell Collagen® is a unique complex of naturally-occurring hydrolyzed collagen, Chondroitin, and hyaluronic acid that can promote healthy joints, hydrated skin, and strong connective tissue.* Lets explore the many benefits of BioCell Collagen® and how this powerful supplement can help you age gracefully. Joint Health BioCell Collagen® can help to promote healthy joints in two ways: by supporting the structure of the joints and by lubricating the joints.* The active ingredients in BioCell Collagen®—hydrolyzed collagen and Chondroitin—work together to support the structure of the joints.* Hydrolyzed collagen is a type of collagen that has been broken down into smaller peptides, making it easier for the body to absorb.* Chondroitin is a molecule that is found in cartilage and helps to attract water to the joints, keeping them lubricated.* Together, these two compounds work synergistically to keep your joints healthy and functioning properly. Skin Health In addition to promoting joint health, BioCell Collagen® can also help to keep your skin hydrated and looking youthful.* That's because one of the key ingredients in BioCell Collagen®, hyaluronic acid, is a molecule that attracts water to the skin cells.* This helps the skin cells to retain moisture, which in turn makes the skin appear plumper and more youthful.* If you're looking for a nutritional supplement that can help support joint health and maintain moisture levels in mature skin, then BioCell Collagen® may be right for you.* This unique complex of hydrolyzed collagen, Chondroitin, and hyaluronic acid can help you age gracefully by keeping your joints healthy and your skin hydrated.* So why not give BioCell Collagen® a try? You may just be surprised at how much difference it can make.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6448) Safe and Effective Joint Pain Relief: Natural Supplements That Work
Date:
July 21, 2022 10:41 AM
Do you suffer from joint pain? If so, you're not alone. In fact, according to the Arthritis Foundation, over 50 million adults in the United States are affected by some form of arthritis. And if that's not bad enough, it's estimated that by 2030, that number will grow to 67 million! The good news is that there are safe and effective ways to relieve joint pain without resorting to over-the-counter drugs. We'll discuss natural supplements like glucosamine, Chondroitin sulfate, and MSM that have been shown to help rebuild cartilage and reduce inflammation. What is joint pain and what are the most common causes? joint pain is a common symptom that can be caused by a variety of conditions. The most common causes include arthritis, bursitis, and tendinitis. Arthritis is a general term used to describe inflammation of the joints. There are many different types of arthritis, but the most common are osteoarthritis and rheumatoid arthritis. Bursitis is the inflammation of the small sacs of fluid that cushion the joint, while tendinitis is the inflammation of the tendons that attach muscle to bone. Joint pain can also be caused by injuries, such as sprains and fractures. In some cases, the exact cause of joint pain cannot be determined. Treatment for joint pain depends on the underlying cause. How can over-the-counter drugs be harmful to your health? The wide availability of over-the-counter (OTC) drugs such as acetaminophen and ibuprofen can be a godsend when we are feeling pain or discomfort. However, it is important to remember that these drugs are potent medications that can also be harmful to our health if we take them inappropriately. Acetaminophen and ibuprofen are both nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs work by reducing inflammation, but they can also have adverse effects on the gastrointestinal tract, kidneys, and liver. In addition, NSAIDs can interact with other medications that we may be taking, so it is important to speak to a healthcare professional before taking them. Although OTC drugs can be helpful when used as directed, it is important to be aware of the potential risks involved in taking them. What are some natural supplements that have been shown to help relieve joint pain safely and effectively? While there are a number of different supplements that have been traditionally used to help relieve joint pain, not all of them have been proven to be effective. However, there are a few natural supplements that have been shown to be safe and effective for this purpose. Glucosamine is a supplement that has been shown to help rebuild cartilage and relieve pain in osteoarthritis sufferers. Another promising supplement is Chondroitin and msm, which helps to reduce inflammation and ease the symptoms of joint pain. Finally, fish oil supplements have also been shown to be effective in reducing inflammation and relieving joint pain. Turmeric, Boswellia, and CBD also reduce inflammation. When used together, these natural supplements can provide significant relief from joint pain. How do glucosamine, Chondroitin sulfate, and MSM work to reduce inflammation and rebuild cartilage tissue? Glucosamine, Chondroitin sulfate, and MSM are all natural compounds that have been shown to be effective in reducing inflammation and rebuilding cartilage tissue. Glucosamine is an amino sugar that is produced naturally by the body. It is a building block of cartilage, and it has been shown to stimulate the production of new cartilage. Chondroitin sulfate is a complex carbohydrate that is also found naturally in the body. It helps to keep cartilage healthy by protecting it from wear and tear. MSM (methylsulfonylmethane) is a sulfur-containing compound that is found naturally in some foods. It has anti-inflammatory properties and has been shown to promote the repair of damaged cartilage. Together, these three compounds can help to reduce inflammation and improve the health of cartilage tissue. How long should you take these supplements for maximum benefit, and when should you stop taking them if you don't experience results within a certain time frame? Many people take supplements in order to improve their health or address a specific health concern. But how long should you take them for? In general, most supplements should be taken for at least 6 to 8 weeks in order to see maximum benefit. However, some people may not see results until 12 weeks of supplementation. Of course, if you're working with a healthcare professional, they can help you determine when to start and stop taking supplements. But in general, 6 to 8 weeks is a good rule of thumb. Don't be afraid to add Turmeric or Boswellia to the mix. These herbs can enhance the effectiveness of the glucosamine, Chondroitin, and MSM. Taking a natural supplement like glucosamine, Chondroitin sulfate, and MSM can be an effective way to reduce inflammation and rebuild cartilage tissue safely and effectively. These supplements have been shown to be safe and effective for this purpose. When taken together, they can provide significant relief from joint pain. It is important to speak to a healthcare professional before taking these supplements if you are taking other medications, as there is potential for adverse effects. Be sure to take 1500mg of each in divided dosages though out each day for at least 6 to 8 weeks in order to see maximum benefit.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6419) What Makes a Good Joint Complex or Formula?
Date:
June 29, 2011 11:44 AM
Glucosamine/Chondroitin/MSMJoint pain is a common medical condition that afflicts billions of people worldwide. It is brought on by many different factors, though most of the cases have been tied to arthritis. The joints are especially susceptible to inflammation in old age partly due to the fact that cartilage health becomes impaired as we age. The good news is that certain organic compounds replenish the cartilage content of joints. Medications and remedies formulated to alleviate joint pain have been extensively studied in the past few decades. Analgesics remain the mainstay of treatment for arthritis to this day, but alternative medicine has also made advances. Proponents of nutritional supplements believe that a good joint formula does not only provide relief from pain but also supplies the proteins necessary for joint health. Glucosamine Joint cartilage comprises a group of complex carbohydrates called polysaccharides or oligosaccharides that are attached to proteins. In a process called glycosylation, enzymes add long unbranched chains of carbohydrates to core proteins and form proteoglycans, which nourish the extracellular matrix found in cartilages. In the case of osteoarthritis, the proteoglycan content of joints dwindle with age. Glucosamine is a precursor to polysaccharides and oligosaccharides. In particular, it is utilized by enzymes to form glycosaminoglycans, which are in turn added to proteoglycans. As a treatment for joint pain, it comes in the form of glucosamine sulfate and glucosamine hydrochloride. It is one of the most promising of all complementary therapies for arthritis as studies have reported positive results. Chondroitin Therapeutic remedies that contain glucosamine often come with Chondroitin. The sulfated form of Chondroitin is a major constituent of proteoglycans, and as such it is generally found in large amounts in joint cartilage in humans. For decades, Chondroitin has been used as a therapeutic remedy for arthritis in conjunction with glucosamine as they are believed to enhance the efficacy of each other. Proponents believe that Chondroitin and glucosamine supply the body with healthy quantities of glycosaminoglycans for use by enzymes in the synthesis of proteoglycans. There is consensus in the scientific community that its long term use for the sole purpose of treating osteoarthritis is safe. In addition, recent studies and clinical trials in the past few years have been very encouraging. MSM Methylsulfonylmethane, often abbreviated as MSM, is a compound listen as an ingredient in joint formulas. Nutraceutical experts believe that the best joint formula currently available contains all three: glucosamine, Chondroitin, and methylsulfonylmethane. While glucosamine and Chondroitin provides nutrition for cartilage tissue, MSM counteracts inflammatory mediators that cause joint pain. Alternative remedies have been the subject of most studies on arthritis in recent years. While analgesics remain commonly used, dietary supplements are becoming increasingly popular among people suffering from joint pain. Glucosamine, Chondroitin, and MSM are the most studied of all supplements formulated for joint pain, the reason why health care providers recommend them first. Grab yourself a joint formula complex and feel the difference!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2352) Hyaluronic acid and your cells, eyes, and skin
Date:
December 17, 2010 10:48 AM
Hyaluronic AcidDiscovered in 1934, hyaluronic acid can be found anywhere there is the need for connective tissue in your body. Your joints, your eyes and your heart all contain hyaluronic acid, and a shortage can lead to a wide range of bodily defects, including the appearance of accelerated aging. It is a glycosaminoglycan, a form of polysaccharide that is not only found in connective tissue and epithelial and neural cells, but is also important in the growth and renewal of body cells. We shall discuss here how hyaluronic acid affects specific areas of your body, and what the effect of a deficiency would mean, but also keeping in mind that an excess of this polysaccharide can also have a serious impact on your health although it offers few side effects worth noting. Hyaluronic Acid and Your Joints The highest concentrations of hyaluronic acid (HA) in your body is found in the synovial fluid, the fluid lubricating contained in your joints, and it is also plays an important role in maintaining the function of cartilage in keeping your joints flexible and well cushioned. It is chemically a glycosaminoglycan that is formed from glucosamine and glucuronic acid. Its production is boosted by Chondroitin, which is why glucosamine and Chondroitin are commonly used supplements for the treatment of arthritis. Specifically, HA joins with collagen and elastin to produce cartilage, and also increases the supply of synovial fluid that maintains lubricity within the joints. Without the synovial fluid your cartilage would soon become worn away and your bones would grind together, eventually seizing up. By taking hyaluronic acid orally as a supplement, you can help to maintain healthy joints by maintaining the integrity of the cartilage and the quality of the synovial fluid. Because the cartilage contains no blood vessels, it is reliant on the synovial fluid to keep it supplied with nutrients, and specifically with HA which is a large part of its structure. Without this important polysaccharide your body would not be able to function: no mobility, dry flaky skin and poor or no eyesight. Hyaluronic Acid and Your Skin Hyaluronic acid occurs in the lower layers of your skin where it helps to maintain a smooth and full appearance to your skin due to its hygroscopic nature in absorbing up to a thousand times its weight of water. For this reason HA is frequently used in skin moisturizing treatments and lotions. HA is not found inside body cells, but appears to be restricted to the extracellular regions between cells where its moisturizing properties are critical in maintaining suppleness. Elastin requires copious quantities of water to remain elastic or it would otherwise become brittle: that is why our skin looks dry and wrinkled when we age. It is due to a lack of moisture: the moisture that hyaluronic acid can bring to the table. The problem is that HA reduces with age and in order to maintain our youthful looks we have to take a supplement. Hyaluronic acid doesn't last long in your skin: it has to be renewed constantly and each day about 50% of the HA content of your skin is lost. It takes about two weeks for the same degree of loss to occur in the synovial fluid of your joints. The look of your skin depends to a very large extent on the extracellular matrix, or what is contained between your skin cells. The more moisture there then the smoother and plumper your skin will appear. As you age, your hyaluronic acid production drops and so your skin becomes increasingly more depleted of moisture. This causes it to dry up and wrinkle. Were there one substance that I would choose as the elixir of life it would be HA, because by taking a regular supplement your natural daily loss is replenished and your skin is given a hand to maintain its soft, moist plumpish look that helps you to keep you looking young. Hyaluronic Acid and Your Eyes The vitreous humor is the liquid inside your eyeball, and it contains a large amount of hyaluronic acid. It helps absorb shock and to maintain the shape of the eyeball. The HA is so important that your body has developed a special set of cells known as the hyalocytes of Balazs that are believed to promote the renewal of hyaluronic acid, and also possibly its breakdown. There is still a lot of research going on into this but the importance of HA in the vitreous humor and other aqueous area of your body is not in question. It helps to retain water and give structure to the liquid media within your body, whether that is between the bones of your joints, in the dermal and epidermal regions of your skin to keep it supple, or in your eyeball. In fact, it is believed to take up 70% - 80% of your eye, and helps to keep the retina in place exactly where it has to be for your eyesight to work. Because Hyaluronic acid is: a) present between the cells in every tissues in your body, and b) a consumable, in that it gets used up rapidly, and c) your biochemistry's ability to regenerate it reduces with age, a supplement is the ideal way in which to maintain its levels in your extracellular system. In some instances injections are given, particularly in expensive anti-wrinkling treatment, but studies have shown that hyaluronic acid baxyl taken as an oral supplement shows an improvement after an average of 3 months treatment. It should be understood that the average person has around 15 grams hyaluronic acid in their body, of which 5 grams is continually degraded and synthesized daily. When you reach an age that your ability to generate HA is impaired, then an oral supplement will be less expensive than injections, the hyaluronic acid of which will also be degraded with time. It won't be long before you need more treatment, and oral supplements are less expensive than private hypodermic injections. A Hyaluronic acid supplement baxyl can be taken to improve the suppleness and appearance of youthful skin, help maintain the integrity of your eyesight and help to reduce the symptoms of arthritis and many other conditions brought on by a reduction in the synovial fluid and hydration of the skeletal and connective tissues of your body. In other words, it helps to keep you looking younger for longer and to keep your joints and your eyesight in good health. Have you had your daily dose of hyaluronic acid today?Baxyl is a liquid form of hyaluronic acid that is easy to take and easily assimilated into the body because its a liquid.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2210) JOINT HEALTH
Date:
December 22, 2005 09:37 AM
Glucosamine & Chondroitin - JOINT HEALTHEveryone old enough to walk appreciates the value of fl exibility and ease of movement. Unfortunately many of us take such good things for granted. A famous folksinger sang, “You don’t know what you’ve got till it’s gone.” That’s certainly true for millions of Americans who live with stiff and uncomfortable joints. Fortunately there are a number of nutrients available that provide the vital components of healthy joint structure and function and ease of mobility. These nutrients are referred to as “chondroprotective agents,” and include glucosamine and Chondroitin, which supply the raw material necessary to produce new cartilage, and may even help rebuild worn cartilage. Other chondroprotective nutrients and herbs, like Cetyl Myristoleate, MSM, and Boswellin, work synergistically with glucosamine and Chondroitin and further support normal joint function To understand how chondroprotective agents work, one must fi rst understand how joints work. The key element in human joints is articular cartilage, the shock-absorbing tissue that connects two bones together and allows pain-free movement. Articular cartilage is comprised of two different molecules, collagen and proteoglycans, with the remainder composed primarily of water (65-85%). Collagen, a protein that binds tissue together, provides elasticity. Proteoglycans, composed of sugars and protein, absorb water, which provides lubrication and resiliency, nature’s shock absorber for your joints. Both compounds are produced by chondrocytes, caretaker cells responsible for the formation and maintenance of cartilage. A defi ciency in any one of the above constituents will increase the likelihood of wear and tear on articular cartilage, which can eventually lead to compromised joint function. Glucosamine and Chondroitin are safe, natural and effective nutrients that support healthy joint function by supplying the materials needed to produce collagen and proteoglycans.
GLUCOSAMINEGlucosamine is composed of glucose (a sugar) and glutamine (an amino acid). It is utilized by chondrocytes to form glycosaminoglycans (GSG) and proteoglycans (PG). Both of these constituents attract and bind water into cartilage, increasing resiliency. Research indicates that glucosamine may actually help your body repair damaged or eroded cartilage. A number of studies have been conducted on glucosamine sulfate and glucosamine hydrochloride, with a preponderance of positive results. Glucosamine sulfate is considered the more effective of the two. One study from the University of Liege in Liege, Belgium studied the effects of glucosamine sulfate on 212 patients with knee osteoarthritis. Participants took either 1,500 mg glucosamine or a placebo once daily for three years. The study compared joint-space width at enrollment, one year, and at the study’s conclusion. The 106 patients on placebo had a progressive jointspace narrowing, while participants taking glucosamine experienced no significant joint-space loss, indicating glucosamine may benefi cially modify cartilage structure.3 A study published in the journal Osteoarthritis and Cartilage in 1998 investigated the in vitro effects of glucosamine sulfate on proteoglycan and collagen production by chondrocytes taken from osteoarthritic articular cartilage. The results showed “a statistically signifi cant stimulation of PG production by chondrocytes from human osteoarthritic cartilage cultured for up to 12 days in 3-dimensional cultures.” 4 Another study from Italy enrolled eighty inpatients with established OA. They received either 1,500 mg of glucosamine sulfate or placebo daily for 30 days. The patients treated with glucosamine sulfate experienced a reduction in symptoms almost twice as large and twice as fast as those receiving placebo. Researchers also used electron microscopy of patient’s articular cartilage to support this hypothesis. Patients who received glucosamine sulfate showed a picture more similar to healthy cartilage. The researchers concluded that glucosamine sulfate tends to rebuild damaged articular cartilage and restore articular function.5
ChondroitinChondroitin is classifi ed as a glycosaminoglycan. It bonds with collagen to form the basis of connective tissue. Chondroitin helps attract fl uid into proteoglycans, thereby bringing nutrients into cartilage and providing shock absorption. While glucosamine helps manufacture and maintain cartilage, Chondroitin keeps cartilage from becoming malnourished. Chondroitin works synergistically with glucosamine, and these two nutrients form the basis of most joint health supplements on the market today. A 6-month randomized, multi-center, double-blind, doubledummy study published in 1996 compared the effectiveness of Chondroitin versus a popular non-steroidal anti-infl ammatory drug (NSAID) in patients with knee osteoarthritis (OA). One hundred and forty-six patients with knee OA were recruited and separated into two groups; an NSAID group and a Chondroitin sulfate (CS) group. The NSAID group was given the NSAID and a placebo for the fi rst month, then placebo alone for months 2-3. The CS group was given the NSAID and CS for the fi rst month, and then CS alone for months 2-3. Both groups were then given 1200mg of CS for months 4-6. “Patients treated with the NSAID showed prompt and plain reduction of clinical symptoms, which, however, reappeared after the end of treatment; in the CS group, the therapeutic response appeared later in time but lasted for up to 3 months after the end of treatment. CS seems to have slow but gradually increasing clinical activity in OA; these benefi ts last for a long period after the end of treatment.”6 NOW® Foods is your source for natural joint support products. Our Extra Strength Glucosamine & Chondroitin is one of our best-selling products, and we also have combination supplements that include MSM, Concentrace® minerals, and more. We also carry both glucosamine and Chondroitin as separate products, as well as in powder and lotion forms.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1064) - US Center for Disease Control, 2005
Date:
December 07, 2005 01:27 PM
“Forty-three million Americans report that a doctor told them they have arthritis or other rheumatic conditions. Another 23 million people have chronic joint symptoms but have not been diagnosed with arthritis. Arthritis is the leading cause of disability in the United States, limiting the activities of more than 16 million adults.” - US Center for Disease Control, 2005 This is of alarming concern, especially if you’re one of the nearly 60 million US adults who live with a joint disorder. Clearly, you don’t need to be reminded of what a struggle it can be. Mundane tasks become major, and major tasks become painful reminders of what life was like when your joints were strong and seemingly indestructible. Many sufferers lose hope, while others hopelessly lose out on so many of life’s activities. Over the past ten years, notable advances in the nutritional sciences have paved the path for landmark products such as Glucosamine, SAMe, Chondroitin, MSM, and others. As a result, millions have found relief in these products and continue to use them in their quest towards healthy mobility. Fortunately, the science behind these popular joint support supplements has done nothing but steadily improve. Celadrin® is perhaps the most convincing proof to date. Let’s examine. In short, Celadrin® is novel blend of acetylated fatty acids, esters and other synergistic agents that enhance cell membranes throughout the body, resulting in greater mobility and more normalized joint function. The extremely high user success rate and virtually complete absence of side effects has helped Celadrin® rise to the rank of joint support extraordinaire. Yes, this is a bold statement. However, just one look at the supporting research is enough to convince even the most skeptical critics of what a true breakthrough it is. Celadrin®’s ability to provide fast, cumulative relief continues to be evidenced by extensive clinical research, as well as a steady flow of eye-opening human trials. Unlike popular non-steroidal anti-inflammatory drugs (NSAIDS) that simply mask joint discomfort, Celadrin® targets the source by enhancing cell membranes and restoring the vital fluids that cushion bones and joints. Ultimately, this is what makes it possible to enjoy a free range of motion without the bone-on-bone grinding that limits so many from their daily activities. Working in much the same manner that other fatty acids do, Celadrin®’s patented blend of esterified fatty acids spark positive changes at the cellular level. As this occurs, cell membranes become more responsive and less prone to articular cartilage deterioration. “How long do I need to take it?” Not only does it work well, studies continue to illustrate Celadrin®’s ability to work fast. This can be attributed to how easily absorbed the active ingredients are. In 2005, a University-led, placebo-controlled study examined 42 patients who struggled with knees that were…let’s just say less than fully functional. After just 30 minutes, 100% of the subjects treated with a topical form of Celadrin® reported significant improvement in joint mobility and support. Even more impressive, each participant demonstrated continuous and restorative benefits over the course of the entire 30 day study. “How do I use Celadrin®?” One of the most appealing elements of Celadrin® is the flexibility that users have when it comes to taking charge of their joint health. It is available in both oral and topical forms, and each is equally effective. Some users have reported greater results by supplementing the oral form while applying the topical lotion directly to the target areas in question. Still, no two people are alike. Accordingly, the severity and nature of each individual concern will vary from person to person. Therefore, it can be wise to determine which application works best for your particular situation. “What if I don’t have joint problems?” For openers, you’re very fortunate. If your joints are strong and fluid, Celadrin® is one of the most effortless ways to keep them that way! Cartilage breakdown is gradual, and occurs over a long, delayed, unsuspecting period of time. In many cases, there is very little warning that your knee or shoulder is about to become part of a frightening and growing statistic. Your joints may feel fine today, but you’d be amazed at how fast that can change. Think of Celadrin® as Cartilage Insurance. You may not see an immediate need to support them right now, but if they do give out, you’ll sincerely wish you had. “What should I look for in a Celadrin® product?” As with every dietary supplement and joint-support product, you should always look for a quality formula from a trusted, well-established manufacturer with a history of producing quality products. NOW® Celadrin® products are scientifically formulated, tested for safety and potency and guaranteed to be of superior quality. Each full serving contains 1.5 g (1500 mg) of Celadrin® along with 300 mg of MSM for additional support. NOW® Celadrin® Liposome Lotion contains 7.5 % Celadrin® along with 1.25% USP Pharmaceutical grade natural Menthol. Both are now available at fine independent health food retailers nationwide.* credits: Jayson Kroner [mailto:jayson.kroner@nowfoods.com]
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=986) Celadrin and MSM Fact Sheet
Date:
December 07, 2005 01:24 PM
Celadrin and MSM Fact SheetNeil E. Levin, CCN, DANLA Certified Clinical Nutritionist, Diplomate in Advanced Nutritional Laboratory Assessment Revised 11/10/05LIKELY USERS: People lacking flexibility or mobility; People wanting temporary control of aches and pains; People wanting to reduce pro-inflammatory body chemicals. KEY INGREDIENT(S): Celadrin® powder 500 mg. Provides 350 mg. of actual EFAC (esterified fatty acid carbons). This is a proprietary blend of Esterified Fatty Acid Carbons of Myristate, Myristoleate, Laurate, Oleate, Palmitate and Palmitoleate in a base of tapioca and silica. MSM 100 mg. MAIN PRODUCT FEATURES: CELADRIN® is an all-natural proprietary matrix of esterified (cetylated) fatty acid carbons (EFAC) derived from tallow of USA-raised cattle. This product is developed through a proprietary process of esterifying oil & has been clinically tested. Celadrin promotes joint health by improving flexibility, pain management and mobility. The myristoleic acids and the cetylated forms may alter the 5-LOX enzyme and change the leukotriene production, inhibiting inflammatory compounds. Celadrin® may offer some noticeable benefits faster than other substances, like glucosamine and Chondroitin. Though it is not a substitute for these important tissue-building nutrients. ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: MSM has synergistic abilities to reduce certain substances in the body which may affect the inflammatory process. Contains Cetyl Myristoleate (CM, CMO), but in a patented blend of other fatty acid carbons. This product (Celadrin ®) has its own clinical studies showing safety and efficacy. Also will be available in a softgel of the same potency (350 mg. of EFAC) as of December 2005 (product 3017, 90 softgels) SERVING SIZE & HOW TO TAKE IT: Three capsules a day, preferably with meals. POSSIBLE SYNERGISTS: Glucosamine, Chondroitin, MSM, Joint Support Products, Manganese, Vitamin C, other Antioxidants CAUTIONS: None. SPECIFIC: None GENERAL: Pregnant and lactating women, and people using prescription drugs, should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new dietary supplement, use common sense and cautiously increase to the full-recommended dose over time, looking for possible side effects. Repeat this process for each new supplement that you start to use.
REFERENCES: 1. J Rheumatol. 2002 Aug;29(8):1708-12. Cetylated Fatty Acids Improve Knee Function in Patients with Osteoarthritis. Hesslink R Jr, Armstrong D 3rd, Nagendran MV, Sreevatsan S, Barathur R.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=985) Quality that you and your customer can trust!
Date:
October 20, 2005 10:10 AM
Quality that you and your customer can trust!
“How do NOW products compare to other brands in terms of selection?” Our 1,700+ SKU product line widely recognized as one of the most complete in the natural products industry. In addition to our extensive selection of dietary supplements, we also affer a full line of herbs, natural foods, aromatherapy, essential oils, herbal teas, herbal extracts, stevia products, natural cosmetics, books, and much more.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=855) NEW PRODUCT ANNOUNCEMENT - Hyaluronic Joint Complex
Date:
August 03, 2005 01:27 PM
NEW PRODUCT ANNOUNCEMENTHyaluronic Joint Complex ™ with Glucosamine, Chondroitin and MSM The Next Generation in Joint Formulas!
2 tablets contain: BioCell Collagen is a trademark of Biocell Technology LLC, Newport Beach, California USA (US patent 6,025,327 - other USA and foreign patents pending). OptiMSM is a trademark of Cardinal Nutrition. Suggested Use: 2 tablets twice daily, or as recommended by your health care professional.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=722) Hyaluronic Joint Complex - w/Glucosa, Chondr, & MSM - The Next Generation in Joint Formula
Date:
June 29, 2005 11:45 AM
Hyaluronic Joint Complex™ with Glucosamine, Chondroitin, and MSM The Next Generation in Joint Formulas Every movement you make requires your joints to help your body flex, bend and twist into that next position. But with time and use, your joints can begin to break down, resulting in discomfort. Source Naturals understands how difficult it is to live with joint discomfort. That’s why we developed HYALURONIC JOINT COMPLEX. This powerful formula combines the most popular, scientifically researched ingredients for joint health—hyaluronic acid, glucosamine, Chondroitin, and MSM. Together, these ingredients promote joint, tendon and ligament flexibility and easy joint movement. Joints are cushions made of flexible and protective cartilage—containing outer layers that surround a lubricating fluid. It is this design of your joint and other connective tissues that gives your body structure, height and the ability to move without damaging the bones and muscles that hold you up. HYALURONIC JOINT COMPLEX provides the key nutrients needed to support this complex structure. BioCell Collagen II®—Hyaluronic Acid Hyaluronic acid is a polysaccharide chain found throughout the body. It is a major component of joint tissue that helps to hold lubricating moisture in joints and cartilage, affecting their resilience, elasticity, and strength. BioCell Collagen II® is a patented hyaluronic acid, which has undergone an absorption enhancing hydrolyzation process that yields low molecular weight hyaluronic acid, Chondroitin sulfate, and Collagen Type II peptides, unlike other preparations that have not been hydrolized. The low weight allows these compounds to deliver greater support for your joints. Glucosamine—An Amino Sugar Glucosamine is an amino sugar—a molecule made from an amino acid and a simple sugar. Amino sugars are the basis of virtually all connective tissues and lubricating fluids in the body. Just as amino acids are the building blocks of proteins, amino sugars are the building blocks of giant molecules called glycosaminoglycans (GAG’s), also known as proteoglycans and mucopolysaccharides. GAG’s are large, spongy, water-holding molecules that form the glue that holds us together. This substance is found in all connective tissue and mucous membranes. Numerous double-blind, placebo-controlled studies have examined the positive effects of oral administration of 1,500 mg of glucosamine sulfate-the amount in one daily use of HYALURONIC JOINT COMPLEX. To ensure optimal absorption, this formula contains glucosamine sulfate, N-acetyl glucosamine and glucosamine HCl. Chondroitin Sulfate Chondroitin sulfate is the most abundant GAG in the body. Its main role is in keeping cartilage fluid and elastic. It is found naturally in the body, where it is one of the critical compounds that makes up connective tissue. Connective tissue is responsible for building and supporting cartilage found in the joints and elsewhere. Dietary Sulfur for Joint Lubrication Both glucosamine sulfate and Chondroitin sulfate provide an additional source of sulfur, a mineral that is important for healthy connective tissue. HYALURONIC JOINT COMPLEX also features MSM, or methylsulfonylmethane, a naturally occurring form of organic sulfur found in body fluids and tissue, cow’s milk, plants and most natural foods. Sulfur may promote joint flexibility due to its role in supporting joint lubrication and movement. A double-blind, placebo-controlled study evaluated the effects of MSM with promising results. Supporting Ingredients for Joint Health: Manganese Ascorbate and Vitamin C Manganese is involved in the production of a wide variety of enzymes. These enzymes influence such biological processes as the production of collagen and the metabolism of protein and cholesterol. Manganese is also necessary for the growth and maintenance of tissues, cartilage and bones. The manganese ascorbate used in this formula also provides 55% vitamin C. Vitamin C is essential for the production and stability of collagen, the major protein in cartilage and connective tissue. It also protects cells from harmful free radicals. Innovative natural products, such as HYALURONIC JOINT COMPLEX, are an integral part of the Wellness Revolution. Taking personal responsibility for your health is at the heart of this revolution. Your local health food outlet is your source for nutritional education and advanced natural products. Source Naturals is pleased to partner with these outlets to bring you HYALURONIC JOINT COMPLEX—the next generation in joint formulas.
References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=526) Inflama Rest - Natural COX-2 Inhibitor for Joint Comfort
Date:
June 02, 2005 12:37 PM
It happens. You reach for something and feel a sudden discomfort. Your joints and muscles may feel tender from overuse. Inside, your cellular systems are out of alignment, resulting in lessened mobility. Source Naturals understands how difficult joint discomfort can be to live with. We are deeply committed to developing well-researched formulas that address the root cause of joint distress. Our Bio-Aligned Formulas™ bring alignment to multiple interdependent body systems. Only this type of indepth formulation can provide the long-term relief you are looking for. Regain your comfort with Source Naturals INFLAMA-REST. Unlike many products that contain just a few ingredients to offer temporary relief, INFLAMA-REST is a Bio-Aligned Formula™, scientifically designed to address aches. INFLAMA-REST goes deep to the underlying cause of joint discomfort. These systems include: inhibition of pathways involved in joint discomfort, joint and muscle function, DNA protection and antioxidant defense. Addressing Joint Comfort on a Deep Cellular Level Discomfort can come from many places. From your head to your toes there are many tissues that can become uncomfortable from everyday use. Joint discomfort starts when stress, such as tissue damage, causes an imbalance of the biochemical pathways on a deep cellular level. The body has its own “innate intelligence” encompassing more than just the thoughts in the brain. It consists of ongoing and complex chemical reactions regulated by a wide variety of enzymes and chemical messengers. These reactions can sometimes get out of balance – but you can control and inhibit key body chemicals that would otherwise lead to cellular irritation. For example, certain types of prostaglandins that regulate normal physiological functions such as blood flow, are maintained at low levels in all our cells under everyday conditions. In response to stress, a message is sent to the outer membranes of certain cells to convert their fatty acids into arachidonic acid, the raw material for prostaglandins. This stress also directs cells to produce Cyclooxygenase enzyme- 2 or COX-2. This enzyme converts arachidonic acid into Prostaglandin E2, a particular type of prostaglandin specifically responsible for irritation on a cellular level. The result: joint discomfort. But that doesn’t have to happen. By supporting inhibition of the culprit COX-2, you can decrease Prostaglandin E2 production to bring your joint tissues back into a healthy and comfortable balance. INFLAMA-REST includes herbs that support inhibition of COX-2 in a variety of pathways. Ginger, turmeric and green tea all support direct COX-2 inhibition. But there are other places in our biochemical communication system where COX-2 production can be inhibited. Two additional factors that lead to COX-2 production are nitric oxide and the enzyme that produces it, nitric oxide synthase (iNOS). Nitric oxide is a free radical associated with cell growth and regeneration, blood vessel elasticity and COX-2 enzyme production. Resveratrol, rosemary and turmeric support iNOS inhibition, thus inhibiting your body’s over-production of nitric oxide and the COX-2 enzyme. A related irritation factor is also one of the latest scientific discoveries in cellular health - Nuclear Factor kappa-B (NF-kappa-B). NF-kappa-B works at the DNA level – at the blueprints of cells. When activated, this factor controls the genes that regulate cell growth, differentiation and regeneration. And blocking this factor is also associated with inhibition of both COX-2 and iNOS enzymes. Stinging nettle, milk thistle and Chinese Skullcap all block unhealthy NF-kappa-B activation in your body and thereby help support COX-2 inhibition. Cytokine Inhibition Compounds called cytokines, or interleukins, can also stimulate biochemical pathways leading to joint discomfort. Cytokines are chemical messengers produced by the immune system to regulate defensive activity when they are stimulated. For example, cytokines are released by macrophages in response to stimuli such as tissue damage. This results in rapid escalation and amplification of cell number and response. Constant stress can shift this system out of balance, resulting in tissue discomfort. Bringing these compounds back into balance can preserve your short-term comfort and longterm health. INFLAMA-REST contains curcumin from the spice turmeric. Curcumin assists the body’s inhibition of cytokine activity to support reduced cellular irritation. And Bioperine®, which is derived from black peppercorns, is added to assist curcumin assimilation. Stress Response: Joints and Muscle Support Inhibition of chemical messengers involved in joint discomfort is just part of a Bio-Aligned strategy for relieving discomfort. Research has shown that emotional stress, particularly long-term, can directly affect the body and set in motion mechanisms that cause physical discomfort. Ashwaganda and Chinese Skullcap (S. baicalensis) are herbs that help modulate the body’s response to stress and may help ease aches and discomfort. Boswellia, ginger, quercetin, milk thistle, feverfew, Oregon grape root and bromelain (an enzyme found in pineapples) provide additional soothing relief to your cells and tissues. Essential nutrients are also vital to maintaining your joint comfort. The tocotrienol forms of vitamin E, along with selenium, protect cell membranes from lipid-based free radicals. Magnesium aids energy metabolism in muscles and can reduce tenderness as well as muscle spasms. Zinc is essential for normal cellular repair mechanisms such as wound healing and is important for the growth and maintenance of connective tissue. And manganese works to protect cells from oxidation and to build healthy connective tissue as well, an essential component of healthy joints and muscles. Protecting Your DNA To reduce cellular irritation, you need to protect the DNA in your cells. DNA is the blueprint for all of the molecules in the body. If your DNA is altered or damaged, then needed molecules may not be produced, leading to short-term and eventually long-term damage. Curcumin, from turmeric, has been shown in in-vitro studies to protect DNA against strand breakage. Quercetin has also been shown to directly protect DNA against strand breakage and base oxidation from free radicals and damaging chemicals, according to recent in-vitro research. Providing Powerful Antioxidant Cellular Protection Antioxidants are selfless bodyguards of your cells. They donate their own electrons to stabilize free radicals in your body. Thus, antioxidants absorb the damage that would have been done to your tissues. Some regulatory chemicals, such as Nitric oxide, are powerful free radicals and oxidants. Oxidants also activate NF-kappa-B. Tissues, lipids, proteins and DNA are extremely sensitive to oxidation. Quercetin, milk thistle, turmeric, ginger, rosemary, vitamin E and resveratrol are all antioxidants that help modulate the activity of these compounds as well as protect cells and tissues from damage. Plus, Superoxide Dismutase (SOD), one of the most important enzyme antioxidants found in your body, has been added in a new cutting-edge form. The vegetarian SOD used in INFLAMA-REST is attached to Gliadin, a wheat protein, that has demonstrated significantly better absorption than SOD alone. Six Lifestyle Strategies for Fewer Aches
Inhibition of COX-2: Turmeric, Ginger, Chinese Skullcap, Green Tea, Resveratrol, Boswellia, Silymarin, White Willow Inhibition of Cytokine Turmeric, Stinging Nettle, Feverfew Inhibition of Rosemary, Green Tea, Resveratrol, Turmeric, Quercetin, Chinese Skullcap NF-kappa-B Activation Silymarin, Chinese Skullcap, Stinging Nettle, Rosemary, Resveratrol Stress Response: Ashwaganda, Magnesium, Chinese Skullcap, Oregon Grape, Feverfew, White Willow DNA Protection Turmeric, Quercetin, Rosemary Antioxidant Defense Silymarin, SOD Gliadin, Turmeric, Rosemary, Tocotrienols, Resveratrol, Ginger, Selenium, Manganese, Zinc Prostaglandin & Leukotrine Synthesis Joint & Muscle Support Inhibition of Nitric Oxide Synthesis Production
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