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Facts about Curamin and its working formula. Darrell Miller 3/30/14
How Curamin Combats Inflammation Pain Darrell Miller 12/19/12
All about curamin Darrell Miller 12/13/12
What Makes Curamin Such A Good Natural Pain Remedy? Darrell Miller 3/7/12
Curamin: benefits and ingredients Darrell Miller 3/6/12
Use Curamin For Painful inflammation and see how your life can change! Darrell Miller 6/15/10
Pain Relief Darrell Miller 6/13/08
Higher Mind - Smart Nutrients for the Performance of a Lifetime... Darrell Miller 6/2/05



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Facts about Curamin and its working formula.
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Date: March 30, 2014 01:14 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Facts about Curamin and its working formula.

Benefits of curcumin

curcumin powderIt is very normal to experience pain and inflammations however, curamin is the answer to any pain problem. What is curamin? It can be described as a blend of all-natural components comprising of curcumin, Boswellia, curcuminoids, nattokinase and DLPA (DL-Phenylalanine). Curcumin has been researched and found to have a broad healing platform, that is, anti cancer, anti-inflammatory, anti-oxidant, anti bacterial and anti-fungal. During post-surgery, it has been proven to ease inflammation and in addition to that, reducing inflammation and swelling in arthritic conditions. Nattokinase is nutrient element in curamin which is an enzyme. The enzyme functions in that it helps breakdown blood clots as they can be painful and moreso, helps in relieving blood pressure.

Inflammations should be well taken care of as research says that, the pains are responsible for all kinds of serious sicknesses such as cancer and painful conditions such as arthritis. The enzyme nattokinase, is very important in relieving inflammations by enhancing circulation in the body thus allowing compounds such as boswellia, pain killer endorphins and curcumin to get to the areas where they are needed most. In addition,it enhances balance of fibrinogen in the body which is associated with muscle damage. Curamin also contains a component by the name DLPA which works in an interconnected mode and furthermore improving moods. Boswellia is termed as a traditional herb which relieves pain by reducing inflammation.
How does curamin work? Through the unique combination of the several components the product comes up with mechanisms that support the anti-inflammatory response within the body. Inflammatory compounds within the the body are inhibited by a combined formula of boswellia and curcumin. Nattokinase is responsible for increased circulation so as to transport beneficial components to areas of need. DLPA is responsible for that positive mood to ensure quick recovery.

Recommended dosage

Two capsules, two times a day is the most appropriate dosage to clients. The manufacturer warns that eight capsules should not be exceeded in 24 hours.

Sources

  1. //www.needs.com/products
  2. //www.medicalpublications.org/curamin.htm

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How Curamin Combats Inflammation Pain
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Date: December 19, 2012 12:08 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Curamin Combats Inflammation Pain

Fact: You can manage pain with natural remedies!ep-10220

Study has revealed the sad fact that four out of every five Americans perceive that pain is a natural inevitable part associated with old age. Athletes on the other hand believe that severe pain is essential for physical fitness. Many people again, think that there are certain disorders that ignite pain and you can do less or nothing to relieve the ache.

In fact, 28% of America's population believes that there is no solution that can eliminate their personal pain concerns. In the contrary, Curamin by EuroPharma is a highly effective herbal remedy that combines four powerful and clinically proven ingredients, into a single award-winning product that offers an ultimate level of pain relief.

Here is a look into how Curamin relieves inflammation pain.

#Curamin's Ingredients The secret behind Curamin's power is blending the best of the best. These ingredients are well known for their fast action in relieving pain associated with inflammation especially in the bones and joints. Here are the four main ingredients used in the formulation of this unprecedented pain reliever.

*DLPA (DL-Phenylalanine) This is a double part amino acid (D phenylalanine & L phenylalanine) that impedes the breakdown of the enkephalin compound, also known as the positive mood enhancer. In addition to that, DLPA converts the L phenylalanine into tyrosine so as to enhance the secretion of two brain chemicals; norepinephrine and dopamine, which ease pain and dissolve inflammation.

*Boswellia Boswellia serrata, also known as Indian frankincense is an anti-inflammatory herb used in the Curamin formula. The boswellic acids prevent the hyperactivity of an enzyme called lipoxygenase, which is often associated with inflammation. This way, it effectively combats inflammation pain.

*Nattokinase This natural ingredient is extracted for a Japanese fermented cheese known as natto, hence its name. The production of this beneficial enzyme can be attributed to a certain bacterium called Bacillus natto. Its benefits in relieving pain come through its action of breaking down clots, promoting the circulation of blood. Thickened blood can intensify pain, and by promoting blood circulation, all other Curamin ingredients are well distributed to every single part of the body.

*Curcumin This powerful, natural compound derived from turmeric requires no detailed introduction. It promotes the body's natural ability to combat inflammation and also contains anti-oxidant properties that are very useful in preventing tissue damage. Its functionality in pain relieving is behind its effectiveness in cutting off pathways that lead to inflammation. Numerous studies have also depicted its ability to promote cognitive-enhancing as well as anti-depressant benefits by igniting neuro-protective brain functions and moderating pain neuro-transmitters.

#How Curamin Relieves Pain

This proprietary formula combats inflammation pain by promoting the body's defense mechanism. In addition to that, it features curcumin BCM-95 which has an enhanced oral bioavailability and is highly soluble, thus availing a full spectrum or curcuminoids that fight pain in a flash. Additionally, the amino acids and Boswellia used in the formulation of Curamin helps the body to absorb the pain alienating ingredients quickly, which earns Curamin its well deserved fast-acting characteristic.

Curcumin BCM-95 has extended blood retention; one among the many attributes that makes Curamin stronger than other plain curcumin products. We cannot forget to mention the fact that Curamin is associated to no known side effects. It combats all types of pain ranging from occasional back pain to chronic pain caused by arthritis. So, next time pain becomes a problem, grab a bottle of Curamin and make your life a whole lot easier.

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All about curamin
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Date: December 13, 2012 11:35 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: All about curamin

For those who never really hard about it, they should know that Curamin contains is up to ten times strong than the regular curcumin products. It's actually one of the best ways through which individuals will be able to balance their body's natural inflammation response and many recent and past studies support its ability. Through the removal of pro inflammatory compounds which are generally present in this plant, the impact of boswellia is very much enhanced.

DLPA was showed in many studies to actually be very helpful with maximizing the effects of enkephalins and endorphins, which are natural and very powerful pain relievers produced by the human body. Nattokinase is rounding up the formula and for those who don't have any idea what it is, they should know it's actually an enzyme. It directly affects muscle pain through its ability to have the fibrinogen levels in the body balanced and at the same time it will also ensure people have a healthy blood circulation in the body. Many people are already aware of the fact that if they take ibuprofen and also aspiring for long periods of time, they will experience serious stomach bleeding and at the same time, if they take Tylenol and ibuprofen, the toxicity in their kidneys and liver will increase very much. 

However, with the more safer and also more effective alternative of Curamin, who would ever want to consider the aforementioned medicines?

Curamin, this is a natural pain killer anyone can take. Its combination of DL-Phenylalanine, boswellia, cuminoids and Curcumin make it a really effective pain reliever. The way it works is that it will help with stopping the triggers that switch on pain pathways and at the same time it will also reduce the inflammation. More than ninety percent of people who have taken Curamin said that in just forty five minutes, they experienced great pain relief. At the same time, they also said there were no side effects to deal with, meaning their kidneys, stomach and intestines didn't suffer any damage. Curamin actually works in conjunction with the body's natural ability to stop inflammations which is the reason why individuals feel pain.

The president and founder of Europharma in the United States said that it is really a great and effective product which everyone who is dealing with inflammations should use. Because he trusts this product so much, millions of Americans have actually turned their attention to it and regard it now as one of the most efficient pain relievers on the market. In 2009 Curamin was awarded the prize for having the best formula so far, a formula which doesn't let people experience any side effects and at the same time, it makes their inflammations and pain go away really quickly. It seems that as time passes, Curamin is also getting better and more and more effective formulas appear. With that being said, everyone who will take Curamin in order relieve his pain or inflammation will feel great in less than an hour!

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What Makes Curamin Such A Good Natural Pain Remedy?
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Date: March 07, 2012 06:57 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Makes Curamin Such A Good Natural Pain Remedy?

Curamin: A Natural Anti-Inflammatory

When nerve endings become irritated, they cause pain. This is because of factors such as lack of sleep, hormonal imbalance, stress, nutritional imbalance, etc. Pain is generally symptomatic of some dysfunction or inflammation in our body and the first reaction for those suffering from it is to reach out for a pain killer. This is where Curamin comes in.

Curamin is a proprietary formula and a curcumin based supplement. Curcumin is a beneficial compound found in turmeric, a popular Indian spice. Turmeric has been used since centuries in the field of alternate medicine like Ayurveda because of its many medicinal properties. The compound, curcumin in fact, has the ability to reduce pain by supporting the body's ability to respond to swelling and inflammation. It has been found equivalent to some popular allopathic pain killers. Apart from this, it also has antioxidant, antibacterial, antiviral, antifungal and anticancer properties and has been found to promote anti depressant and cognitive enhancement benefits.

Curamin Formula

Curamin is a product having a formula based on this particular compound of turmeric and is therefore extracted out of natural ingredients and has been found to have minimal side effects. Curamin, apart from other ingredients, also contains a strain of curcumin that has a high absorption factor which makes it several times more effective and stronger than plain curcumin products. It not only balances the body's response to inflammation but also has been observed to have a consistent and long lasting effect. Therefore, this makes curamin the most effective form of curcumin available.

Studies have established that curamin is safe and does not interfere with kidney, liver or stomach functions. The safe dosage recommended by the company is two pills twice a day for pain alleviation and not more than 8 pills within a 24-hour period. An overdose of such herbal products may sometimes cause intestinal discomfort at the most.

Main Ingredients of Curamin

Curamin has four principle ingredients that have an overall effect on inflammation caused in the bones and joints due to arthritis or overuse and exercise. These ingredients include: DL-Phenylalanine or DLPA is a two part amino acid that acts as a positive mood enhancer by preventing the breakdown of enkephalin compound and also helps in the production of brain chemicals like dopamine and norepinephrine. Boswellia that helps to prevent the activity of the inflammatory enzyme. Curcumin which helps block multiple pathways within the body to retard and stop inflammation. Nattokinase which is an enzyme that helps the fast absorption of the ingredients through the body by promoting blood flow and improving circulation.

Benefits of Curamin

Curamin has helped people suffering from problems like arthritis, migraines, bursitis, and soreness caused by accidents or injuries. It also helps build resistance and immunity to inflammation concerned especially with the bones and joints.

Curamin, being a plant based product has no toxic effects and is available with many natural medicine practitioners and pharmacies. It is a very effective natural alternative to allopathic drugs and painkillers that over a long term use cause many side effects, some of which are potent.

If you are in pain, try curamin today!

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Curamin: benefits and ingredients
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Date: March 06, 2012 07:54 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Curamin: benefits and ingredients

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Curamin: benefits and ingredients

It's a well known fact that most chronic pain in whatever part of the body is usually caused by inflammations. Such pain can only be relieved or eased by reducing multiple inflammations in the body. Most over the counter drugs produce dangerous side effects and as such, are greatly discouraged.

Scientists have recently made a breakthrough by discovering a combination of herbs known as Curamin that effectively treat or ease most instances of chronic pain usually caused by presence inflammations in the body

Curamin is an effective natural pain reliever and anti-inflammatory drug that has captured lots of headlines of late. Curamin essentially works by cutting off multiple or several pathways that cause inflammations in the body hence reduce chronic pain as a result.

Curamin is basically a combination of two powerful herbs turmeric and Boswellia along with essential amino acids that helps the body to quickly absorb the pain relieving ingredients.

Curamin is an effective alternative to over the counter pain killers (OTC) which normally produce serious side effects such as liver damage, kidney damage or even in some instances heart attack. Curamin is 100% safe to use meaning it produces no side effects whatsoever.

Curamin is a fast pain reliever that doesn't have to be taken after every four hours unlike most pharmaceutical drugs. Curamin is a fast pain reliever essentially because, it is usually absorbed into the blood stream quickly, hence brings instant relief to patients as a result.

Curamin can be used to ease or treat all manner of chronic pain that include, joint pain, bone pain, back pain, arthritis etc. The plant based medicine contains fout key ingredients, which help in easing several types of chronic pain.

Here are four main ingredients contained in Curamin Curamin ingredients:

Curcumin

Curcumin a natural element derived from turmeric which contains anti -inflammatory properties. Curcumin is also an excellent antioxidant. Curcumin essentially works by cutting off multiple or several pathways that cause inflammations in the body. As if that's not all, Curcumin has also been discovered to contain properties that enhance brain function and is also an effective anti-depressant

Boswellia

Boswellia is another effective ingredient contained in Curamin. Boswellia work by preventing hyperactivity of an inflammatory enzyme called lipoxygenase.

DLPA or DL-Phenylalanine

DLPA is a double part amino acid that works by preventing the breakdown of compound enkephalin which is responsible for positive mood or feelings.

Nattokinase

Nattokinase is another very important enzyme that aids the flow of blood. Nattokinase plays a very important role in Curamin as it helps in ensuring that all Curamin ingredients are distributed or taken to all parts of the body for maximum relief against pain. Nattokinase is a very helpful blood thinning ingredient derived from soya plant.

Last but not least, Natural anti- inflammatory remedies or herbs reduce the body's inflammation without producing any negative side effects. The herbs can either be ingested or applied externally. Zero side effects means that an over dose of Curamin can only cause stomach upset or diarrhea only to a lesser extent. Curamin can be bought inform of capsule, powder or tablet format.

Grab some today and feel the difference curamin can make in your life.

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Use Curamin For Painful inflammation and see how your life can change!
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Date: June 15, 2010 05:10 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Use Curamin For Painful inflammation and see how your life can change!

Curamin (End Inflammation Pain) 120 caps from EuroPharma Everyone experiences occasional pain at some time in their lives. We use the word pain in our jargon to describe something unpleasant and to indicate the necessity of toughening up such as “no pain no gain”. As common as the word pain may be, there are many misconceptions about pain. Four out of five Americans believe that occasional pain is just natural and unavoidable due largely to getting older. More than one quarter of Americans believe there is absolutely nothing they can do to relieve their personal pain.

Pain is a warning signal that something has gone wrong in the body or that something is damaged. Pain is so unpleasant that it motivates you to remove yourself from the cause of this damage as quickly and completely as possible.

There are four ways to relieve occasional pain:

1. You can leave the pain alone, but flood the body with feel-good substances that push the pain signals out from your consciousness (drugs).

2. you can put the person asleep and do surgical procedures to cut nerves and stop the pain.

3. You can impact the nervous system the internal wiring that carry the pain signals to dull them so that the signal becomes less distinct and weaker.

4. You can target what is causing the pain in the first place (most recommended). Occasional pain can be perfectly normal for instance, starting a new exercise routine when you are a bit out of shape. When dealing with type of pain, helping the body to balance its inflammation response can have tremendous impact.

This is where curamin is the answer to pain problems. turmeric root sample for article Curamin contains four high potency ingredients that make it work so well. The first ingredient is curcumin from Turmeric. Curcumin is a super antioxidant with a ORAC value of 1592.27 each gram. That’s 24 times stronger than blueberries. Curamin also contains Boswellia, DLPA (DL-Phenylalanine) which help fight inflammation and maximize the endorphins and enkiphalins in our own body. It finally contains nattokinase which is a systemic enzyme known to help improve circulation.

They all break down as follows:

DLPA: DL-Phenylalanine is an amino acid consisting of equal parts D-phenylalanine and L-Phenylalanine. D- inhibits the breakdown or compounds called enkephalins. Enkephalins are associated with positive mood and have been shown to relieve occasional muscle pain due to exercise or overuse. L- is converted into tyrosine, which in turn is used to produce brain chemicals norepinephrine and dopamine.

Boswellia: Clinically tested boswellia helps reduce the activity of the inflammatory enzyme, 5-LOX (lipoxygenase). A compound (beta boswellic acid) found in boswellia which interferes with its benefitical activity has been removed, greatly increasing the effectiveness of this extract. boswellia sample for article Curcumin: Curcumin, a compound found in the spice of turmeric, inhibits multiple inflammation pathways in the body. It is also a potent antioxidant. Some of the benefits associated with curcumin include immune system modulation, protection from oxidative stress, and support the body’s natural anti-inflammatory response. The specialized extract in this formula has the highest absorption of any curcumin extract available for maximum health benefit. (Found in Curamin)

Nattokinase: the enzyme nattokinase helps promote blood flow, aiding the other ingredients in the formula to reach all areas of the body.

So if you are suffering from chronic pain, give curamin a try and see how well you can feel. If you are concerned about its effectiveness, have no fear, VitaNet ®, LLC offers a 100% Money back guarantee if the product does not work for you.

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Pain Relief
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Date: June 13, 2008 12:18 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Pain Relief

DL-Phenylalanine has been found to work in conjunction with the body’s natural ability to relieve pain. It helps to lengthen the lifespan of the chemicals in the brain that ease pain. It is especially effective in relieving pain from arthritis and aching muscles.

Some chronic pain can be treated with DL-Phenylalanine through the stimulation of nerve pathways in the brain that control pain. Enhanced pain relief has been discovered when D-phenylalanine is used in conjunction with prescribed pain killers. This manufactured form of phenylalanine is used to block an enzyme in the nervous system that increases pain signals. The interruption of pain signals allows the healing mechanisms of the body to begin working faster.

DL-Phenylalanine is a chemical combination of half L-phenylalanine and half D-phenylalanine. L-Phenylalanine is the natural form of phenylalanine found in proteins all over the body. It is found in foods like beef, poultry, pork, fish, eggs, milk, yogurt, cheese, nuts, seeds and certain soy products. D-Phenylalanine is a synthesized form of the chemical, which means it is produced in a laboratory.

Phenylalanine as an Amino Acid:

Amino acids perform various major functions in the body. They assist in fulfilling the body’s basic needs from minerals and vitamins. They can act as neurotransmitters, which carry signals to and from the brain. They also aid in other parts of the body for communication between nerve cells.

Phenylalanine is one of the essential amino acids found in protein. This means it is required for human health, but cannot be manufactured by the human body. Therefore it has to be supplied through food consumption. It can also be found and taken in the form of powder, capsule, tablet or a topical cream. In the body, phenylalanine is converted into tyrosine, which is another amino acid needed to make protein. It is also needed to make certain brain chemicals and thyroid hormones. Phenylalanine deficiency signs include:

* Confusion
* Decreased alertness
* Lack of energy
* Diminished appetite
* Decreased memory

Phenylalanine Warnings:

A rare disorder called phenylketonuria (PKU) happens in humans who are missing the enzyme required to metabolize phenylalanine. Symptoms of this disorder tend to appear between the ages of 3-6 months. These include:

* Eczema
* Developmental delay
* Abnormally small head circumference
* Hyperactivity

If PKU is not treated within the first three weeks of life, it can cause severe and irreversible mental retardation. Women who are pregnant or nursing should avoid taking phenylalanine as a supplement in any form. DL-Phenylalanine may cause hyperactivity, jitteriness and anxiety in children.

Phenylalanine is the major ingredient in the artificial sweetener known as aspartame. Products containing this sweetener are required by law to carry warnings on their labels for phenylketonurics. People who have PKU can be severely injured by ingesting the sweetener. Products containing this artificial sweetener include diet sodas, sugarless gums and some sugar substitutes. Some sugar-free versions of Jello, puddings, ice creams, candies and various other items also contain aspartame.

Other Phenylalanine Uses:

Some individuals have reported that taking DL-Phenylalanine has improved their mood and aided in treating depression. This is the result of a higher rate of production of the brain chemicals dopamine and norepinephrine. These chemicals, when out of balance, cause depression, stress and frustration. Elevation of the levels of these chemicals have an anti-depressant effect in the body.

One study suggests that D-phenylalanine has been shown to improve some symptoms associated with Parkinson’s disease. These include: depression, rigidity, walking problems and speech problems.

The combination of L-phenylalanine and UVA radiation may be used to treat the symptoms of vitiligo. This condition involves de-pigmentation (white patches) of skin. The use of L-phenylalanine may help to re-pigment these patches, but further study is necessary.

DL-Phenylalanine has many uses and benefits if taken correctly. As with any new dietary supplement, consult your physician before beginning a new routine.



--
Vitanet ®, LLC

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Higher Mind - Smart Nutrients for the Performance of a Lifetime...
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Date: June 02, 2005 12:18 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Higher Mind - Smart Nutrients for the Performance of a Lifetime...

Our adult years are the time to reap the fruit of an active, meaningful life – appreciated by family and friends who value our experience and knowledge. For some, however, their later years are clouded by a mental decline that erodes their capacity to enjoy life. More of us are becoming apprehensive about the future health of our minds. Will we still be able to communicate our needs as well as our wisdom? As science focuses its investigative might on the workings of the human brain, new findings suggest that it is possible to enjoy a vital, healthy brain and mind – well into old age. Based on compelling research, Source Naturals formulated HIGHER MIND. It contains the most important Neuroceuticals™ now recognized by nutrition scientists – including phosphatidyl serine, a natural nutrient that promotes cognitive function. The connection is clear: nourish your brain; enrich your life.

To have a healthy, well-functioning brain and nervous system, we need the correct nutrients. Our diets must provide the necessary raw materials for nerve cells to grow, for the synthesis of neurochemicals, and for the maintenance of nerve cell membranes. Nutritional deficiencies can alter the brain’s metabolism, which is expressed by changes in perception and thinking, behavior and mood.

Brain Cells – Issued at Birth

Before birth, neurons (nerve cells) are created at the amazing rate of 15 million per hour. As infants, we have over 100 billion neurons, but this is the most we will ever have because – unlike most other cells in our body – nerve cells do not reproduce. A different strategy is used to replace the neurons that are naturally lost throughout life: nerve cells repair themselves and grow by extending branches of nerve fibers called dendrites (from the Latin word for tree). These are the communication links with other neurons that form the circuitry of the brain. A single neuron may be in contact with up to a hundred thousand others! When the density of this fragile organic communication network decreases, we experience a corresponding decline in mental acuity.

Brain Cell Membranes

The membrane is the working surface of a cell. It needs to be strong yet flexible, so the cell can maintain its integrity and be able to move and change shape. The membrane regulates the flow of nutrients into the cell and the removal of waste, plus controls the passage of molecular messages from outside the cell to its interior. Membrane ion pumps use a third of the cell’s energy just to maintain the correct ratio of sodium to potassium. In neurons, a rapid exchange of sodium and potassium ions across the nerve membrane is responsible for their unique ability to generate the electrical impulses that are the basis of all communication in the nervous system. As cells age, their membranes become less fluid and more rigid. Key membrane molecules called phospholipids are crucial to the health of neuron membranes, allowing the brain to maintain its youthful quality. The phospholipids in HIGHER MIND – especially phosphatidyl serine and phosphatidyl choline – are essential nutritional supplements for the aging brain.

Phosphatidyl Serine – Key to Cognition

For the past decade, researchers have been investigating the role in brain health of a remarkable neuroceutical, phosphatidyl serine (PS). This key structural molecule is integral to the matrix of fats and proteins that compose cell membranes. Although PS is found in all the cells of the body, its highest concentration is in nerve cell membranes. PS is rarely found in the foods we eat, so the body has to synthesize it, but the process is energy- intensive and becomes less efficient with age. Consequently, our levels of PS tend to decline as we get older. PS taken as a dietary supplement is well-absorbed, readily reaching the brain, where it helps create more effective, well-structured nerve cell membranes. The positive effects of PS supplementation have been demonstrated by 23 clinical studies with over 1200 human subjects, ages 43 to 90. Consistent and statistically significant results have confirmed the value of PS in improving age-related cognitive decline, as well as in improving behavioral aspects such as apathy and withdrawal.1 A major study concluded that for one particular measurable parameter of higher mental functions, PS recipients achieved scores of persons roughly 12 years younger.2 Nerve Growth Factor (NGF) is one of the most important proteins the body makes. It enables neurons to extend dendrites out to other neurons, allowing the brain to maintain an effective communication network. In experiments, PS enhanced the production and reception of NGF, which tend to drop off radically with age.3 The effects of PS at the cellular level are manifest in the performance of the brain as a whole. Subjects taking PS showed increased levels of brain energy metabolism. This enhancement corresponded to higher performances on cognitive tests.4

The Chemistry of Thought

Science now understands the role of neurotransmitters in regulating the body’s complex network of behavior. Neurotransmitters are the chemicals used by neurons to communicate with each other. Activated by a neuron’s electrical impulse, neurotransmitters travel between nerve cells, where they excite or inhibit (in various degrees) the electrical impulse in neighboring cells. One of HIGHER MIND’S key strategies is to improve the brain’s ability to produce and use acetylcholine, a key excitatory neurotransmitter. Acetylcholine is essential for both the storage and recall of memory, and partly responsible for concentration and focus. It also plays a significant role in muscular coordination. Patients showing cognitive decline may exhibit reduced ability to synthesize and utilize acetylcholine.5 The chemical building blocks of acetylcholine and other neurotransmitters are called precursors. The most important one for acetylcholine is DMAE (dimethylaminoethanol). This natural substance is found in various fish, such as anchovies and sardines. Supplements of DMAE (and phosphatidyl choline) promote increased levels of choline in the brain. Acetylcholine is created when an acetyl group is attached to the choline molecule, with the help of choline acetyl transferase (CAT), a key brain enzyme. Acetyl L-carnitine is an amino acid that activates this enzyme. Acetyl L-carnitine may also help reduce lipofuscin deposits in the brain because of its involvement in the metabolism of fatty acids.6 Lipofuscin is composed of oxidized fats and proteins; the brown “age spots” on the back of an elderly person’s hand are made of lipofuscin. The amino acid L-pyroglutamic acid sensitizes the acetylcholine receptor sites on a neuron membrane. A given amount of acetylcholine will then have a larger, more powerful effect. Studies have shown that supplements of L-pyroglutamic acid seem to enhance the ability to focus, remember, and learn.

Total Nutrition for the Brain

The neurotransmitters dopamine and noradrenalin are critical to motor coordination, motivation, concentration, and alertness. Like acetylcholine, their production tends to decline with age. The precursors and activators of dopamine and noradrenalin included in HIGHER MIND are the amino acids N-Acetyl L-Tyrosine and DL-Phenylalanine (DLPA), plus folic acid, vitamins B-3, B-6, and C. DLPA is also a precursor to PEA, a neuroamine that has a stimulating effect on the brain. Glutamine is an amino acid precursor to glutamic acid, a major excitatory neurotransmitter involved in mental activity and learning. Glutamine acts as an alternative fuel source for the brain when blood sugar levels are low. It also helps the brain dispose of waste ammonia, which is a natural result of protein breakdown but is irritating to neurons even at low levels. GABA is a dietary amino acid which is also an inhibitory neurotransmitter. GABA works to calm and balance the mind, enhancing mental focus. Along with taurine, these two relaxing neurotransmitters provide a balancing influence to the other, excitatory neurotransmitters. Taurine is found in brain tissue more than anywhere else in the body. It has antioxidant properties and serves as a nerve cell membrane stabilizer, preventing excessive or erratic electrical activity in the brain.

The Importance of Magnesium

Magnesium must be present in adequate amounts in the synaptic gaps between neurons or the neurons become hyper-reactive: causing noises to sound excessively loud and emotional reactions to be extreme. Magnesium also activates a key enzyme responsible for maintaining cellular sodium- potassium balance, which is absolutely essential to the electrical activity of nerve cells, as well as to the existence of the cell itself. (Cells would burst if the sodium-potassium ratio were wrong.) Magnesium also helps relax cerebral blood vessels and is important to the manufacture of ATP, the chief energy molecule of the brain. A buildup of aluminum has been found in the brains of some elderly. In 1989, the British medical journal Lancet published a study showing that drinking water with aluminum can increase the risk of damage by up to 50%. An abundant natural element, aluminum is now a common feature in our culture. It’s found in tap water, cookware, deodorants, beverage containers, baked goods, and of course as aluminum foil. In the brain, aluminum breaks down the structure of neurons – causing them to starve – by displacing magnesium from tubulin, a glycoprotein responsible for making microtubules. These tiny pipe-like structures within a neuron provide needed rigidity, as well as transport nutrients from the nucleus down the dendrites to the ends of the nerve cell. Magnesium malate is an excellent form of magnesium that ensures neurons receive this vital mineral.

B is for Brain Vitamins

HIGHER MIND also contains a high profile of B vitamins and other key nutrients that are often N A T U R A L S S O U R C E Strategies for Wellness SM ¤ lacking in older individuals. A deficiency in any of the B vitamins can alter nerve function and psychological well-being. Thiamine (B-1), known as the “nerve vitamin,” was first recognized because its deficiency caused beriberi, a degenerative nerve disease. Thiamine is part of the structure of nerve cell membranes and is important to the reparative process that neurons need to offset the stress of continual firing of the electrical impulse. Low amounts of thiamine can cause cell malnutrition in the hypothalamus, the brain’s memory center. 7 NAD and NADH, two coenzyme forms of Niacin (B-3), are the most plentiful coenzymes in the brain. They are essential to hundreds of enzymatic reactions, including ones that produce energy. NADH can stimulate the synthesis of key mood-elevating neurotransmitters. It is also one of the body’s most potent antioxidants. Pantothenic acid (B-5), cyanocobalamin (B-12), and folic acid are required to form the myelin sheath – the insulating covering of nerve fibers. A diet low in pantothenic acid has been shown to make test subjects emotionally upset, irritable, and depressed.7 A lack of B-12 can result in poor concentration and, in severe deficiencies, hallucinations. Pyridoxine (B-6) is precursor to over 60 enzymatic reactions and is involved in the synthesis of several neurotransmitters.

Brain Power

Brain cells almost exclusively burn glucose for their energy (other cells can also burn fat), and typically require 50% of all the glucose in the blood. Two B-like vitamins help in the utilization of glucose: PAK (pyridoxine alpha-ketoglutarate) may potentiate the effects of insulin and improve glucose utilization to the cells;8 Biotin is important for the transformation of glucose into energy in the brain. Lipoic acid and coenzyme Q10 are metabolic energizers that help produce ATP, the primary energy molecule in the body. Since the brain uses 20% of the body’s total energy supply, efficient ATP production is vital. Lipoic acid and CoQ10 are also powerful antioxidants that help regenerate other antioxidants in the body. The blood vessels feeding the brain become less efficient as we pass middle age. Since the brain depends on the bloodstream to deliver nutrients and oxygen and to remove waste, the quality of this blood flow is paramount to proper brain nutrition. Ginkgo biloba leaf extract has been shown in scientific studies to increase blood flow to the brain by helping vessels to dilate. It also promotes the smoothness and healthy integrity of blood vessel linings.

For the Life of Your Mind Without proper nutrition, the brain will deteriorate; therefore strategies are needed to both enhance current brain function and protect it throughout life. Based on the latest scientific findings, Source Naturals HIGHER MIND is formulated with neuroceuticals that support the mental functions that tend to decline with age. They give your brain the nourishment it needs to integrate perception, memory, and learning into a more comprehensive awareness – so you can excel for a lifetime.

References
1. Palmieri, G., et al. (1987). Clin. Trials J. 24: 73- 83.
2. Crook, T.H., et al. (1991). Neurol. 41: 644-49.
3. Nunzi, M.G., et al. In Phospholipids: Biochemical, Pharmaceutical and Analytical Considerations (ed. I. Hanin and G. Pepeu).
New York: Plenum Press, 1990.
4. Heiss, W.D., et al. (1993). Annals N.Y. Acad. Sci. 695: 327-31.
5. Passeri, M., et al. (1990). Int. J. Clin. Pharm. Res. X(1/2): 75-79.
6. Kohjimoto, Y., et al. (1988). Japanese Journal of Pharmacology 48(3): 365-71.
7. Philpott, William H. Brain Allergies: the Psychonutrient Connection. New Canaan: Keats, 1987.
8. Passariello, N., et al. (1983). Int. J. Clin. Pharmacol. Ther. Toxicol. 21: 252-56.



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