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  Messages 1-11 from 11 matching the search criteria.
What Cellular Mitochondria Does in the Body Darrell Miller 4/28/22
Study: Following a choline-rich diet may offer transgenerationalprotection against Alzheimer's disease Darrell Miller 4/24/19
Top health benefits of broccoli - Best health and food tips Darrell Miller 1/28/17
Maternal B12 deficiency may increase child's risk of type-2 diabetes Darrell Miller 11/30/16
What Is The HerbThyme Good For? Darrell Miller 12/16/11
The pediatrics academy has raised its earlier recommendation to 400 IU per day. Darrell Miller 10/14/08
Vitamin D Supplements Darrell Miller 7/29/08
Best Sugar Balance Svetol (green coffee extract) Darrell Miller 5/5/06
Magnesium matters Darrell Miller 12/16/05
Pregnant and eating for two... Darrell Miller 10/21/05
Mother's Choice with Iron - Scientific Prenatal Nutrition! Darrell Miller 6/3/05



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What Cellular Mitochondria Does in the Body
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Date: April 28, 2022 04:19 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: What Cellular Mitochondria Does in the Body

If you want to stay healthy, it's important that you know what cellular mitochondria does in the body. Mitochondria are organelles found in the cytoplasm of cells. They are responsible for producing energy for the cell. Without them, the cell would not be able to function properly. We will discuss the role of mitochondria in the body, and how they impact our health.

What are mitochondria and what do they do in the body

Mitochondria are organelles that play an important role in the energy metabolism of cells. Most of the oxygen we breathe is used by mitochondria to convert glucose from the food we eat into ATP, the energy molecule used by our cells. Therefore, mitochondria are often referred to as the "powerhouses" of the cell. In addition to producing ATP, mitochondria also have other important functions, such as regulating cell growth and death, as well as calcium homeostasis. Mitochondria are unique in that they have their own DNA separate from the DNA in the cell nucleus. This mitochondrial DNA is passed down from mother to child, which is why defects in mitochondrial function can lead to diseases that are inherited in a Maternal lineage. Although most of our cells contain only a single nucleus, they may contain hundreds or even thousands of mitochondria. This allows them to produce enough ATP to meet the energy needs of the cell.

How mitochondrial dysfunction can lead to health problems

Mitochondria are integral to many essential physiological processes in the body. Not only do they produce energy for cells, but they also play a key role in maintaining cellular structures and initiating cell division. Therefore, any disruption of normal mitochondrial function can have far-reaching consequences for overall health and well-being. Maladaptive responses to environmental stressors, such as chemical exposure or radiation, are among the most common causes of mitochondrial dysfunction. These stressors result in damage to mitochondrial DNA and can cause problems with cell division and abnormal growth patterns, which can lead to a range of disorders and chronic diseases. For example, mitochondrial dysfunction has been linked to conditions like Alzheimer's disease and type 2 diabetes, as well as cardiovascular disease and cancer. Therefore, it is important to understand the role that mitochondria play in maintaining healthy functioning bodies and take proactive steps to prevent or reverse damage from maladaptive responses to environmental stressors.

Mitochondria and Longevity

Mitochondria are specialized organelles found within our cells that perform many critical functions, including generating energy to support cellular processes and maintaining healthy cell function. These organelles are the site of many important chemical reactions, often referred to as oxidative phosphorylation or metabolism. Studies have shown that Proper functioning of these organelles is essential for healthy aging, and may be a key factor in determining how long we live. By promoting mitochondria health and making lifestyle changes that help to promote healthy mitochondria, we can take an important step towards optimizing our longevity potential. This includes eating a nutrient-rich diet with a focus on foods high in antioxidants, managing stress levels through regular exercise and relaxation techniques, and avoiding environmental toxins that can damage mitochondria health. Through such strategies, we can give ourselves the best chance at living a long, full life.

Ways to protect your mitochondria and keep them healthy with PQQ

PQQ, or pyrroloquinoline quinone, is an important molecule for the functioning of mitochondria in the human body. This compound plays a crucial role in adenosine triphosphate (ATP) synthesis, the fundamental energy currency of biological systems. By driving cellular processes that release energy for metabolic use, PQQ plays a key role in maintaining mitochondrial health and efficiency. Additionally, PQQ has been shown to exhibit powerful antioxidant properties, which help to mitigate the effects of oxidative stress on mitochondria and other critical cells in the body. Overall, PQQ is an essential component of healthy mitochondrial function and a crucial nutrient for energy production and overall metabolic health.

D-ribose, the Mitochondria, and Energy

D-ribose is a naturally occurring sugar that plays an important role in cellular metabolism and energy production. This nutrient is especially important for cells that rely on a lot of energy, such as those found in the heart and muscles. D-ribose helps these cells to generate adenosine triphosphate, or ATP, which is the main energy currency used by cells to drive chemical reactions. Additionally, research has suggested that d-ribose can help to improve physical endurance and reduce the pain and stiffness associated with exercise, making it an important part of a healthy, active lifestyle.

Also, D-ribose is a simple sugar that plays an important role in the structure and function of mitochondria, the powerhouses of the cell. In addition to supplying energy to the cells, mitochondria also help to regulate cell growth and death. D-ribose is essential for the proper function of mitochondria, and it plays a key role in energy production. Studies have shown that D-ribose can help to improve mitochondrial function and reduce fatigue. In addition, D-ribose supplements have been shown to improve exercise performance and increase energy levels. These effects are likely due to the ability of D-ribose to help the body produce more ATP, the energy currency of the cell. For these reasons, D-ribose is an important nutrient for maintaining healthy mitochondria and supporting cellular energy production.

Another important nutrient for the mitochondria is CoQ10

The process of producing energy is called oxidative phosphorylation, and it involves the transfer of electrons from nutrients to oxygen. This reaction creates a proton gradient across the mitochondrial membrane, which is used to generate ATP, the energy currency of the cell. Coenzyme Q10 (CoQ10) is an important component of this process. It acts as an electron carrier, shuttling electrons between enzymes in the respiratory chain. It also helps to maintain the proton gradient, allowing the mitochondria to continue generating ATP. Without CoQ10, oxidative phosphorylation would grind to a halt, and cells would quickly run out of energy. Consequently, CoQ10 plays a vital role in energy production and cellular metabolism.

The bottom line is that both D-ribose and CoQ10 are important nutrients the body needs to maintain optimal energy levels. If you’re feeling run down, low on energy, or just generally not your best, consider taking a supplement containing these two nutrients. You may be surprised at how much better you feel once you start including them in your diet. What’s stopping you from giving them a try?

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Study: Following a choline-rich diet may offer transgenerationalprotection against Alzheimer's disease
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Date: April 24, 2019 03:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Study: Following a choline-rich diet may offer transgenerationalprotection against Alzheimer's disease





Lack of nutrition can end up damaging cells and bring out the worst traits in our genes. A new study found that a maternal high diet in choline can protect the offspring from getting Alzheimer's disease in the future even if the choline levels in the offspring are low. The study was done on mice that were genetically predisposed to Alzheimer's. The body makes choline naturally, but some needs to be consumed in order to receive the amount that is required for healthy cellular functions.

Key Takeaways:

  • The nutrients that we take are like instructions to the body that build up our cells and tell them how to operate and communicate.
  • The benefits of nutritional instructions to the body is to strengthen our genetics and prevent diseases, while a lack initiates changes in our genes and cause diseases.
  • It has been shown from research that nutritional instructions when taken by the mother can be passed on to generations through the genetic code.

"The mice that were born from mothers on choline-rich diets developed fewer disease-associated brain changes. They also exhibited improved memory skills. Even when the descendants didn’t receive choline in their diet, they still enjoyed the benefits of brain protection from their mother’s nutrient-rich diet."

Read more: https://www.naturalnews.com/2019-03-11-study-following-a-choline-rich-diet-protection-against-alzheimers-disease.html

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Top health benefits of broccoli - Best health and food tips
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Date: January 28, 2017 11:16 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Top health benefits of broccoli - Best health and food tips





Broccoli is a healthful food that may have a wide variety of beneficial effects on your health, due to its high levels of potassium, zinc, magnesium, calcium, phosphorous, vitamin A, vitamin C, vitamin K, and beta-carotene. These nutrients may help to regulate blood pressure, promote eye health, protect the bones, boost immunity, improve heart health, and avoid birth defects caused by certain Maternal vitamin deficiencies. It may even improve the health of your skin, and may protect the skin from ultraviolet radiation when applied to the skin as an extract.

https://www.youtube.com/watch?v=3fs3L3O-ZUk&rel=0


Key Takeaways:

  • Broccoli is an edible green plant in the cabbage family whose large flowering head is eaten as a vegetable.
  • It is a cool season annual crop. Sprouting broccoli has a larger number of heads with many thin stalks. Purple cauliflower is a type of broccoli sold in southern Italy, Spain, and the United Kingdom.
  • It has a head shaped like cauliflower, but consisting of tiny flower buds. It sometimes, but not always, has a purple cast to the tips of the flower buds.

"Broccoli is an edible green plant in the cabbage family whose large flowering head is eaten as a vegetable."

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Maternal B12 deficiency may increase child's risk of type-2 diabetes
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Date: November 30, 2016 06:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Maternal B12 deficiency may increase child's risk of type-2 diabetes





A study presented at the Society for Endocrinology’s annual conference has shown that pregnant women who do not consume enough vitamin B12 may be putting their children at risk of developing type 2 diabetes. It is believed that these women have higher BMI’s due to a poor diet and deliver babies with lower birth weight and higher cholesterol. The babies also have a higher chance of having a higher insulin resistance.

Key Takeaways:

  • Vitamin B 12 is naturally found in animal products, including fish, meat, poultry, eggs and milk, meaning deficiency is more likely in those following a vegan diet.
  • that babies born to mothers with B 12 deficiency had higher than normal lepton levels. As B12 is involved in methyl reactions in the body which can affect whether genes are turned on and off, we suspect it may be the latter.
  • The nutritional environment provided by the mother can permanently program the baby's health. we also see that Maternal B 12 deficiency may affect fat metabolism and contribute to this risk.

"Vitamin B12 is naturally found in animal products, including fish, meat, poultry, eggs and milk, meaning deficiency is more likely in those following a vegan diet."



Reference:

https://www.sciencedaily.com/releases/2016/11/161107111017.htm

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What Is The HerbThyme Good For?
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Date: December 16, 2011 02:28 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is The HerbThyme Good For?

What is Thyme?

Thyme is the common name for the plant known as Thymus vulgaris. This herb has a sharp aroma. Its leaves are small and curled in appearance. Such leaves measure about 3 to 5 millimeters in length and 1 to 3 millimeters in width. The color of the leaves is green to gray on the upper part and pale green to whitish in the proximal part. This herb is abundantly found in several places in Asia, Europe and Mediterranean countries. And because of influences, nowadays, thyme is also widely cultivated in North America. It grows best in tropical areas with humid soils. It can thrive even in drought and can also grow in mountain areas.

Thyme has many culinary uses as well as health benefits to the human body. During the ancient times, thyme is commonly used as an embalming agent. It is popularly used in Egypt to preserve the mummies of their deceased rulers or pharaohs. In Greece, it was widely employed in temples because of its soothing and relaxing aromatic property. For the Romans, thyme is widely used as a flavoring to their cheese and liquors. It adds an aromatic flavor to the food or beverage, making it more palatable. Other traditions use this herb as incense for the dead to guide the soul of the dead and guarantee its journey into the next life.

In addition, thyme also has an antiseptic property. During wars in the ancient times, this herb is popular as a topical application on wounds. Today, this herb can is also used as a mouthwash for sores and oral wounds.

The active ingredient in thyme is called thymol. An oil extract of thyme consists of about 15 to 60 % thymol. The most promising property of thymol is its antiseptic quality. In fact, thymol is the considered to be the main ingredient of many popular mouthwashes and toothpastes. Before the discovery of many antibiotics, thyme extracts was popularly used as a medication for wounds and certain skin irritations. Also, thyme extracts can also be employed as an anti – fungal agent on conditions such as Athlete’s foot and toenail fungal infections. Commercially, thymol is also used as an ingredient among many hand sanitizers and cleansers which are alcohol – free and all – natural.

Aside from it external use as an antiseptic, thyme extracts can also be made into tea and used as a relief treatment for respiratory problems such as coughs and bronchitis. And because of its antiseptic property, thyme extract made into a tincture has a promising effect to improve inflammations of the throat. This can also be used as gargles about three times per day to improve sores in the oral mucous membranes. It cans show improvement after three to five days of use.

Another health use of thyme is that it can also be used to help in Maternal labor and childbirth. Clinical studies have shown that thyme has an oxytocin – like property which can induce uterine contractions during labor. After childbirth, it can also be useful in facilitating a faster delivery of the placenta. Its antiseptic property is also useful in the prevention of Maternal infections brought about by childbirth.

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The pediatrics academy has raised its earlier recommendation to 400 IU per day.
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Date: October 14, 2008 10:03 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The pediatrics academy has raised its earlier recommendation to 400 IU per day.

The American Academy of Pediatrics (AAP) today announced that it has doubled the amount of vitamin D recommended for infants, children and adolescents. The increase, from 200 international units (IU) to 400 IU per day, starting in the first few days of life, was detailed at the group’s annual meeting in Boston. The new advice replaces an academy recommendation issued in 2003.

"We are doubling the recommended amount of vitamin D children need each day because evidence has shown this could have life-long health benefits," said Frank Greer, M.D., FAAP, chair of the AAP Committee on Nutrition and co-author of the report. “Supplementation is important because most children will not get enough vitamin D through diet alone.”

"Breastfeeding is the best source of nutrition for infants. However, because of vitamin D deficiencies in the Maternal diet, which affect the vitamin D in a mother’s milk, it is important that breastfed infants receive supplements of vitamin D,” said Carol Wagner, M.D., FAAP, member of the AAP Section on Breastfeeding Executive Committee and co-author of the report.

The new advice is based on mounting research about potential benefits from vitamin D besides keeping bones strong, including suggestions that it might reduce risks for cancer, diabetes and heart disease. But the evidence isn't conclusive and there is no consensus on how much of the vitamin would be needed for disease prevention.

"We know 400 IU a day is safe and prevents rickets," Greer said. "We don't have any idea if that amount of vitamin D is enough for other diseases. We also don't know if anything over 400 is safe."

The AAP also made these recommendations:

Infants who are breast-fed or partially breast-fed receive 400 IU a day of vitamin D in supplements, beginning in the first few days of life, continuing unless the infant starts taking at least one quart a day of vitamin D-fortified formula or whole milk, although whole milk should not be introduced until the child has turned 1. Non-breast-fed children and older children should also receive a vitamin D supplement of 400 IU per day.

Adolescents who do not obtain 400 IU of vitamin D per day through foods should receive a supplement containing that amount.

Children at increased risk of vitamin D deficiency (for example, those taking anti-seizure medications) may need higher doses, but this should only be done in consultation with a health-care professional. The new recommendations were expected to be published in the November issue of the journal Pediatrics.

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Vitamin D Supplements
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Date: July 29, 2008 02:55 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamin D Supplements

Scientists at the Children’s Hospital and Research Center in Oakland, California have recently begun studying whether there is substantial convincing biological or behavioral evidence that links vitamin D deficiency to brain dysfunction. The study found that there is biological evidence which proves that there is an important role for vitamin D in the development of the brain and its function. Supplementation for groups that are chronically low in vitamin D has been found to be extremely beneficial. Vitamin D is involved in brain function through its wide distribution of vitamin D receptors throughout the brain.

Vitamin D affects the proteins in the brain that are known to be involved directly with learning, memory, motor control, and possibly even Maternal and social behavior. Research has shown that supplementation is beneficial to those groups whose vitamin D status is extremely low, especially nursing infants, the elderly, and African Americans, but the need for further study has been established. The authors of the study argue that vitamin D supplementation is necessary for those groups that are at risk.

Increased vitamin D levels protect the body against osteoporosis, cancer, and multiple sclerosis. There is now evidence that suggests that vitamin D may help protect against a potentially dangerous rise in blood pressure which occurs in some people as they get older. A study that was published in the American Journal of Clinical Nutrition had researchers finding that as many as 60 percent of whites and more than 90 percent of blacks who participated in the third National Health and Nutrition Examination Survey had insufficient blood levels of vitamin D.

Researchers also investigated the association between vitamin D, blood pressure, and age. This investigation found that people with lower blood levels of vitamin D had significantly higher increases in systolic blood pressure as they aged than did those people who had healthy levels. Actually, the age-related rise in blood pressure turned out to be 20 percent lower in those people who had healthy vitamin D levels, as oppose to those people who did not. This suggests that vitamin D deficiency may play a critical role in high blood pressure development.

Many other studies have suggested that there is a role for vitamin D in reducing blood pressure. According to Vin Tangpricha MD, PhD., an assistant professor of Medicine in the Division of Endocrinology, Diabetes, and Lipids at Emory University School of Medicine, there is not enough evidence that vitamin D prevents hypertension available, however, because vitamin D insufficiency is highly prevalent throughout the United States, it may be a good idea to take a vitamin D supplement solely because of the strong evidence on vitamin D’s ability to prevent osteoporotic fractures. It has been noted that further studies are needed in order to determine vitamin D’s effect on blood pressure.

Additionally, it needs to be determined if giving all patients vitamin D will help lower blood pressure. Those people who have a family history of other risk factors that are associated with high blood pressure, such as being older than sixty-five, should have their blood pressure checked regularly. Be sure to look for more studies and information on the effects of supplemental vitamin D on both white and black habitants of the United States to help battle vitamin D deficiency. To learn more about supplemental vitamin D, contact your local health food provider.

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Best Sugar Balance Svetol (green coffee extract)
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Date: May 05, 2006 06:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Best Sugar Balance Svetol (green coffee extract)

Ingredients

Best Sugar Balance featuring Svetol® Svetol® is an extract of green coffee obtained by the use of a traditional patented extraction process from the beans of the species Coffea canephora robusta Pierre. This species is particularly rich in the constituent known as chlorogenic acid. Svetol® green coffee extract contains less than 2% caffeine. The extract is standardized to contain between 45-50% chlorogenic acids.

In vitro (test tube) and in vivo research suggests that chlorogenic acids present in coffee may have the ability to regulate blood sugar concentrations after meals by acting on the intestinal absorption of glucose and improving the body's glucose tolerance. Clinical evidence also suggests that Svetol® green coffee extract may help to maintain a healthy blood sugar level when used as a part of the diet.*

Benefits

Maintains healthy blood sugar levels when used as a part of the diet*

CHLOROGENIC ACIDS

Chlorogenic acid is the major polyphenol compound found in Svetol® green coffee bean extract. In vitro and animal studies have been conducted to determine the potential actions of this polyphenol. Studies report that chlorogenic acid and related compounds have significant antioxidant potential and are responsible for the high reported antioxidant benefit of green coffee. Several studies suggest that consumption of coffee in the diet is one factor that is correlated to the maintenance of healthy neural function and healthy aging. Coffee has also been shown in vitro to suppress the production of various free radicals. The chlorogenic acid content of coffee has been determined to be a major factor in the free radical quenching properties of coffee. A study was conducted to assess the activity of coffee extracts against the production of hydroxyl radicals in an in vitro system. It was found that coffee extracts possessed significant suppressive activity against hydroxyl radicals. Of the compounds assumed to be responsible for this effect, the researchers concluded that the chlorogenic acids played a major role with some contributions from other compounds found in the extract. This compound may also strongly contribute to any potential neuroprotective effects seen with coffee consumption.1

Two further studies highlight a possible mechanism by which chlorogenic acid mediates its antioxidant activity. In one study, the FRAP (Ferric Reducing Antioxidant Power) assay was used to measure and compare the iron-reducing capacity of chlorogenic acid and caffeine. It was shown that the chlorogenic acid content of the samples tested was highly correlated with iron-reducing activity in this assay. Moreover, lighter roasted coffee samples (closer in nature to green coffee) had the highest iron-reducing activity. Caffeine did not influence the iron-reducing activity of the coffee samples.2 Iron compounds are known to mediate the production of radicals and often serve as catalysts for their production in the body. A second study shows that chlorogenic acid can bind to and Chelate certain iron compounds, preventing them from catalyzing radical-producing reactions. In this way, chlorogenic acid acts as a powerful antioxidant.3

Chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health.

Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT). More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year. The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee Chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health.

Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT).

More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year.

The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee on a daily basis. In this study, green tea consumption was not associated with any benefits on glucose concentrations.5

It is likely that the chlorogenic acid found in coffee plays a role in supporting healthy glucose metabolism, whereas the role of caffeine is not clear, with some reports suggesting an adverse effect on sugar metabolism.

A second study further confirms an effect of chlorogenic acid at inhibiting the absorption of glucose from the diet. This effect occurs in the small intestine. In this study, nine healthy fasted volunteers consumed 25 grams of glucose in 400 ml of water (the control group), caffeinated coffee, or decaffeinated coffee. Frequent blood samples were taken over the next 3 hours. It was found that glucose and insulin concentrations were higher 30 minutes after the consumption of caffeinated coffee than with either decaffeinated coffee or control (water).While caffeine has specific biological effects on raising glucose levels and impacting insulin profiles, chlorogenic acid was shown to have an antagonistic effect on glucose transport. Previous studies have also shown that chlorogenic acid significantly delays glucose uptake from the small intestine.6

RESEARCH ON SVETOL®

Svetol® is a unique extract of Coffea canephora robusta green coffee beans containing between 45 and 50% chlorogenic acids with less than 2% total caffeine concentration. As outlined above, many studies highlight the potential benefits of coffee compounds, including chlorogenic acid, for providing protection against free radicals and promoting healthy glucose metabolism. A number of other potential benefits have been discovered for these compounds. Svetol® has also been the subject of preliminary clinical studies that have shown exciting results.

In a pilot study, the effect of Svetol® on sugar concentrations after meals was evaluated in 15 individuals. In the same trial, the longer-term effects of Svetol® on weight management were also evaluated. Blood sugar concentrations were measured on two separate occasions. Patients were administered an oral glucose tolerance test (OGTT) in which they consumed a standard amount of sugar and had their blood sugar levels measured 1 hour after sugar intake. The first measurement was made on day 1 prior to taking Svetol® and the second OGTT was performed on day 2, after beginning the Svetol® regimen in which one tablet (200 mg per tablet) was administered 3 times during the day. Patients were fasted for at least 8 hours prior to the testing. The results showed that Svetol® was able to reduce blood sugar concentrations in 60% of the subjects. The mean reduction of blood sugar concentration in these individuals was 50%. The treatment was continued following the same regimen for 6 weeks to assess the impact of Svetol® on weight. The average weight loss of the participants was 1.5 kg (3.3 lbs) over the treatment period. 7

Based on the studies mentioned above and other related research on the ingredients in Svetol®, scientists have proposed two mechanisms of action whereby Svetol® may influence the metabolism and processing of glucose. The first mechanism seems to be an inhibitory action on glucose absorption from the diet. Svetol® may affect the uptake of glucose in the small intestine by modulating factors needed for sugar absorption.

The second mechanism relates to possible effects of Svetol® in the liver's ability to produce glucose. Chlorogenic acids have been shown in vitro and in animal studies to modulate the effects of certain enzymes in the liver that catalyze the production of glucose. By having this dual effect on sugar absorption and sugar production, Svetol® is an effective product for maintaining healthy blood sugar levels when used as a part of the diet.*

SAFETY

Svetol® is a natural food extract from green coffee beans containing a standardized amount of chlorogenic acid. Studies have shown that chlorogenic acid (up to 500 mg/kg/day) given to pregnant rats from the 5th through 12th day of gestation caused no Maternal or fetal mortality and no adverse effects on the nervous system. Chlorogenic acids have also been shown to be non-mutagenic in tests on bacteria such as the Ames test. The LD50 of chlorogenic acids has been determined to be higher than 2500 mg/kg body weight. Svetol® is also extremely low in caffeine, with less than 2% caffeine contained in the extract, and is not expected to have any of caffeine's stimulant effects. Svetol® is extremely safe with no adverse effects having been reported while taking Svetol® at the recommended dosage.7

*This statement has not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease.

Scientific References

1) Daglia M, Racchi M, Papetti A, Lanni C, Govoni S,Gazzani G. In vitro and ex vivo antihydroxyl radical activity of green and roasted coffee. J Agric Food Chem.2004 Mar 24;52(6):1700-4.

2) Moreira DP, Monteiro MC, Ribeiro-Alves M, Donangelo CM, Trugo LC. Contribution of chlorogenic acids to the iron-reducing activity of coffee beverages. J Agric Food Chem. 2005 Mar 9;53(5):1399-402.

3) Kono Y, Kashine S,Yoneyama T, Sakamoto Y, Matsui Y, Shibata H. Iron chelation by chlorogenic acid as a natural antioxidant. Biosci Biotechnol Biochem. 1998 Jan;62(1):22-7.

4) Zang LY, Cosma G, Gardner H, Castranova V, Vallyathan V. Effect of chlorogenic acid on hydroxyl radical. Mol Cell Biochem. 2003 May;247(1-2):205-10.

5) Yamaji T, Mizoue T, Tabata S, Ogawa S, Yamaguchi K, Shimizu E, Mineshita M, Kono S. Coffee consumption and glucose tolerance status in middle-aged Japanese men.Diabetologia. 2004 Dec;47(12):2145-51. Epub 2004 Dec 15.

6) Johnston KL, Clifford MN, Morgan LM. Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine. Am J Clin Nutr. 2003 Oct;78(4):728-33.

7) Berkem.Text on Svetol®.Gardonne, France: November 2005. Best Sugar Balance Svetol Green Coffee Extract



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Magnesium matters
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Date: December 16, 2005 09:49 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Magnesium matters

Magnesium matters

Research published in June in The Journal of Nutrition described how magnesium deficiency in female rats affected their offspring. The team at the Division of Endocrinology and Metabolism of National Institute of Nutrition in India found that Maternal magnesium deficiency increased body fat and induced insulin resistance in offspring by the time they reached 6 months. Also, the addition of perinatal magnesium-restricted diet impaired offspring’s glucose tolerance.

This follows a study published in Diabetes Care in May that found an association between magnesium deficiency and insulin resistance during childhood. According to the authors, based at the University of Virginia and the State University of New York at Buffalo, magnesium deficiency has already been associated with insulin resistance and increased risk of type II diabetes in adults. They concluded, “Magnesium supplementation or increased intake of magnesium rich foods may be an important tool in the prevention of type II diabetes in obese children.”



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Pregnant and eating for two...
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Date: October 21, 2005 01:36 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Pregnant and eating for two...

Not - Quite - Dual - Nutrition

It’s time to ditch a dietary cliché often foisted on expectant moms. “try to keep in mind that you are not eating for two, you are carefully eating for one,” write Catherine Jones and prenatal nutrition expert Rose Ann Hudson in Eating for Pregnancy (Marlowe & Company), who add that pregnancy “is not a time to skip meal, eat junk food or lad up on empty calories for quick energy.” The idea is to eat a nutritious diet that allows you to gain weight gradually as your baby grows.

It helps to be at a healthy weight when starting a family. Being overweight makes conception more difficult, and at least one study ahs found a link between excess Maternal weight and the risk of a birth defect called cleft palate (in which the roof of the mouth is split from behind the teeth to the nasal cavity). However, dieting during pregnancy may actually program a child for obesity by rewiring the developing brain, so try to lose weight before you try to conceive.

How much should you expect to gain over the course of nine months? “A lot depends on your unique circumstances and the advice of your health care provider, but in general you can anticipate adding from two to five pounds a month for the first 14 weeks and roughly a pound a week thereafter until your due date-between 25 and 35 pounds in total. That translates into roughly and extra 300 calories a day; Jones and Hudson say that more nourishment may be necessary if you are breastfeeding, extremely active or carrying more than one child. Since stress and anxiety often lead to out-of-control eating (and gaining), be sure to tend to your own emotional needs during what can be a very exhilarating, yet sometimes overwhelming, time of life.

For maximum nutrition try to eat a variety of foods while avoiding anything that provokes morning sickness. Whole grains provide both steady energy (unlike sugar-fueled spikes and crashes) and B vitamins to boot. Do not scrimp on fat-your baby’s developing nervous system depends on it-but “don’t use your pregnancy as an excuse to pig out, either,” warn Jones and Hudson. Stick with such unsaturated fats as olive oil along with rich sources of omega-3 fatty acids like flax seed oil. You definitely want to indulge in those omega-3s, which appear to boost infant intellectual development. Fish is a fine source of both omega-3 and the high-quality protein needed to build your baby’s tissues, but beware: Some species such as fresh tuna, swordfish, tilefish and king mackerel, can be contaminated with mercury. Your best low-mercury bets are catfish, pollock, salmon, and shrimp. (Other good protein sources include chicken, cottage cheese, lean red meat, yogurt and milk, all organically sourced whenever possible.)

Supplemental fish oil is another omega-3 possibility because mercury is found in the muscle of fish and not in the oil,” according to OSU’s Jane Higdon, who suggests consulting your health care practitioner for advice. “If I was going to take a fish oil supplement, I’d look for one that the manufacturer is testing for PCBs (an industrial pollutant),” such as products that meet California’s Proposition 65 standards.

Don’t forget to stock the fridge with fresh produce. Fruits and veggies are richly endowed with vitamins and minerals; for example, making like Popeye and downing your spinach helps ensure you get plenty of folic acid and iron.

These superfoods also supply phytonutrients, substances that may actually help protect your baby against cancer even as they enhance your own well-being. Studies on the link between Maternal diet and childhood cancer protection are in the early stages according to Dr. David Williams, a researcher at the Linus Pauling Institute, but he says that shouldn’t stop you from loading up on cancer-fighting green stuff. “Certainly among the vegetables the cruciferous ones (the broccoli family) are particularly valuable in protecting against cancer,” he says. “These vegetables are also a good source of fiber and vitamin C.”



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Mother's Choice with Iron - Scientific Prenatal Nutrition!
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Date: June 03, 2005 06:23 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Mother's Choice with Iron - Scientific Prenatal Nutrition!

Mothers Choice with Iron PreNatal Nutrition

You’re expecting a baby—and right now nothing could be more important than ensuring the health of your developing child. At this crucial time, what could be more basic than providing the nutrients that are the very substance of the new life you’re carrying? At every critical stage of pregnancy, your baby’s cells and tissues are literally formed from the nutrients you take in. Source Naturals is deeply committed to giving your newborn every chance for optimal health. That’s why we developed MOTHER’S CHOICE Prenatal Multiple. MOTHER’S CHOICE combines a comprehensive vitamin-mineral blend with advanced nutrients that reflect the latest scientific research. And each bottle comes with a separate package of Arctic Pure™ DHA softgels. DHA is a fatty acid that is crucial for baby’s brain development from the earliest stages of pregnancy through the breastfeeding years. MOTHER’S CHOICE also supports your health and vitality, with a blend of traditional herbs used for centuries to relieve morning sickness and leg edema. MOTHER’S CHOICE: because nothing is too good for you and your baby.

Go the Source for Scientifically Based Formulation

MOTHER’S CHOICE PRENATAL MULTIPLE was expertly formulated to supply a full range of essential vitamins and minerals, in potencies effective for Maternal health and fetal development, while safe for the fetus.

Healthy Fetal Development

MOTHER’S CHOICE contains ingredients that reflect the latest findings in fetal nutrition.

  • • Choline: The National Academy of Sciences recommends that pregnant and nursing women increase choline intake to support fetal brain development (450 mg daily during pregnancy and 550 mg while nursing). MOTHER’S CHOICE is the one of the few prenatal multiples to supply 450 mg.
  • • Folic Acid: Folic acid, along with vitamin B-12, is required for DNA synthesis and helps prevent neural tube defects. The U.S. Public Health Service recommends that women of childbearing age consume 400 mcg of folic acid daily. During pregnancy, the need increases to 800 mcg, the amount in MOTHER’S CHOICE. B-12 is supplied as methylcobalamin and adenosylcobalamin, the active coenzyme forms found in breast milk.
  • • Docosahexaenoic Acid (DHA): MOTHER’S CHOICE is one of the few prenatal formulas to include this omega-3 fatty acid. Source Naturals sells its MOTHER’S CHOICE formula with ArcticPure DHA from premium fish oil concentrate in separately packaged softgels. Patented ArcticPure DHA has no fishy taste. Pregnant mothers transfer DHA to the fetus to support brain and retinal development, while DHA is supplied to the newborn via breast milk.
  • • Iron: Iron is a critical component of oxygen-carrying hemoglobin. During the second and third trimesters, women need increased iron to supply the growing fetus and placenta.

    Enjoy Your Special Time!

    Pregnancy should be one of the high points of your life, but typical discomforts can get in the way. MOTHER’S CHOICE features herbs traditionally used during pregnancy. Morning Sickness: Ginger root and peppermint leaf are traditional remedies for the nausea associated with morning sickness, and chamomile has soothing properties. Leg Comfort: Vitamin E has been shown to relieve nocturnal leg cramps, while bilberry supports healthy capillaries and veins.

    Take Charge of Your Pregnancy

    Source Naturals understands your deep desire to safeguard your baby’s health and development. With MOTHER’S CHOICE you have the resources to act on that concern. MOTHER’S CHOICE: for a vibrant pregnancy and a good start on life for your newborn.

    CAUTION: Pregnant or breastfeeding women should consult a health care professional before using this or any dietary supplement.



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