Four tablets contain: Vitamin A (as beta-carotene 8,500 IU & palmitate 4,000 IU) 12,500 IU
Vitamin C (as ascorbic acid & ascorbyl palmitate) 1,000 mg
Vitamin E (as d-alpha tocopheryl) 400 IU
Riboflavin (vitamin B-2) 25 mg
Zinc (as monomethionine [OptiZinc®]) 15 mg
Selenium (as L-selenomethionine [SelenoPure™] 200 mcg
& sodium selenite)
Manganese (as manganese succinate) 10 mg

gamma-Vitamin E Complex 500 mg
Turmeric Rhizome Extract 95% 300 mg
alpha-Lipoic Acid & 210 mg
R-Lipoic Acid
N-Acetyl Cysteine 200 mg
Wheat Sprouts 150 mg

Quercetin 100 mg
Amla Fruit (Phyllanthus emblica) 100 mg
Grape Seed Extract 100 mg
(Proanthodyn™)
Green Tea Extract 100 mg
(95% polyphenols, 35% EGCG) Hawthorn Berry Extract (4:1) 100 mg
Mega H- Microcluster™ 100 mg
Silica Hydride Powder
Rosemary Leaf Extract 100 mg
(20% diterpenes)
Ginger Root 100 mg
Ginger Root Ext. (5% gingerols) 80 mg
SOD 80 mg (superoxide dismutase [GliSODin®])
Milk Thistle Seed Extract 80 mg
Yielding 66 mg Silymarin
Pomegranate Seed Extract 60 mg
(40% elagitannins)
Pomegranate Seed Extract 60 mg
(40% elagitannins) Red Raspberry Leaf Extract 50 mg
(40% elagitannins)
Blueberry Leaf Extract 50 mg
(20% chlorogenic acid)
L-Carnosine 50 mg
Ginkgo Biloba Leaf 24% 40 mg
(50:1 Extract)
Coenzyme Q10 30 mg
L-Glutathione 25 mg
Total Resveratrols (from 20 mg
Polygonum cuspidatum Extract)
Bilberry Fruit 20 mg
Std. Ext. (37% anthocyanosides)
Tocotrienol Complex 20 mg
(Tocomax®)
Myricetin 20 mg
DMAE (as bitartrate) 20 mg
Lycopene 3 mg
Lutein (FloraGLO®) 3 mg
Astaxanthin 1 mg

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=548)

Date: June 04, 2005 02:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Pycnogenol Complex - The Next Generation of Antioxidant Protection

Pycnogenol Complex

If there’s one factor that has the greatest negative impact on our health, it is the damage done to our cells by free radicals. These highly unstable molecules disrupt the biochemical processes that regulate life. Although a natural product of oxygen metabolism in the body, free radicals are also produced in vast quantities by modern technology. Our bodies’ natural defenses simply have not been able to keep up with the onslaught of these dangerous products of civilization. On the other hand, technology has offered help by identifying some of nature’s most powerful weapons against free radical attack. Source Naturals PYCNOGENOL® COMPLEX is an unprecedented combination of these extremely potent plantbased antioxidants, or Plantioxidants™. Consider them your antidote to the industrial revolution.

How free radicals are formed and their effect on the body

Oxygen both makes life, and takes life. The energy that animates us comes from the biochemical reactions that burn oxygen within our cells. And though carefully regulated by the body, this biological combustion, over time, inevitably leads to cellular damage. If oxidation is not carefully controlled, tissues are damaged faster than the body can repair them. This is caused by an excess of over-reactive, electron hungry molecules called oxidants or “free radicals,” which tend to disrupt normal cellular activity. Free radicals attack a cell’s membrane and can even damage its hereditary blueprint (DNA). Since free radicals are a natural result of certain metabolic reactions, the body synthesizes several types of antioxidant enzymes to neutralize them. In addition, we get essential antioxidants from the foods we eat. Vitamins C, E and beta carotene are the ones found most often in our diet. During this century, our environment has become a perpetual source of free radical contamination, primarily from radiation and the chemical pollution in our air, water and food. Today, we are literally overwhelmed with more free radicals than our bodies are accustomed to handling. Fortunately, science has found that certain plants contain special antioxidants that are far more powerful than the vitamins we typically get in our diet. With this knowledge, Source Naturals formulated PYCNOGENOL® COMPLEX, the most advanced combination of Plantioxidants available today in one product. Pycnogenol® is the proprietary name of a natural plant product made from the bark of the European coastal pine, Pinus maritima.

Natural protection against free radicals

Pycnogenol® Complex – A Cornucopia of Health Our knowledge of pine bark goes back nearly 500 years, to when the French explorer, Jacques Cartier, reported that a tea made from pine tree bark by Native Americans saved the lives of his crew who were dying of scurvy. Nutrition scientists have since isolated the extraordinary antioxidant compounds of pine bark. They have also discovered many other unique antioxidants throughout the plant kingdom. Plants have evolved bioflavonoids to protect themselves from free radical damage. One of the most abundant compounds in the plant kingdom, bioflavonoids are found in the pigments of bark, rinds, seeds, leaves and flowers.

Natural antioxidants in Pycnogenol® Complex

The active ingredients of Source Naturals PYCNOGENOL® COMPLEX are derived from a diverse range of nature’s plenty: pine bark, green tea, turmeric spice, rosemary, grape seeds, milk thistle seeds, bilberries, hawthorn berries and ginkgo leaves. Each of these Plantioxidants is an exceptional free radical scavenger, and each has a tendency to concentrate in a different organ of the body, thus providing targeted protection. And since their primary function is to capture free radicals, these Plantioxidants free up vitamin C, so it can perform its many other vital functions.

Defense Plants The two headliners of Source Naturals PYCNOGENOL® COMPLEX are the pine bark extract, Pycnogenol®, and an extract from grape seeds, Proanthodyn™. Their unsurpassed antioxidant activity – up to 20 times that of Vitamin C and up to 50 times that of Vitamin E – comes from a high concentration of proanthocyanidins.

Why Pycnogenol® Complex is formulated with extracts of pine bark and grape seed

These highly bioavailable flavonoids are able to cross the Blood-Brain Barrier, and can stay in the bloodstream for up to 72 hours. Few other nutritional antioxidants cross this barrier, and none do it as well. Proanthocyanidins therefore offer the brain and central nervous system unparalleled antioxidant protection. In particular, proanthocyanidins may help reduce the formation of lipofuscin, a brown waste material made of free radical-damaged proteins and fats. Over time, lipofuscin deposits form in the brain, heart, and skin. The “age” or “liver” spots that develop on the backs of some elderly peoples’ hands are made of lipofuscin. Because they’re rich in unsaturated fatty acids, cell membranes are the primary site of free radical attack. Proanthocyanidins are able to protect against both water- and fat-soluble free radicals. Also, their chemical structure is incorporated within cell membranes, making proanthocyanidins very effective in preventing damage to the cell’s interior. This is vital, because if a cell’s DNA is disrupted, it could lead to the abnormal reproduction of that cell. For many years now, Europeans have used pine bark and grape seed extracts to maintain vein and capillary health. Proanthocyanidins support the circulatory system by helping to keep collagen and elastin, the essential constituents of vessel walls, from breaking down during times of imbalance. And most importantly, proanthocyanidins can help prevent the oxidation of LDL cholesterol in the bloodstream. Scientists now recognize that it’s not cholesterol itself, but the oxidation of cholesterol that can be problematic.

How Plantioxidants benefit different organs in the body

The Power of Diversity

In addition to the broad protection offered by Pycnogenol® and Proanthodyn, Source Naturals PYCNOGENOL® COMPLEX offers an outstanding array of other Plantioxidants. Each has unique abilities to protect the body from oxidants. For several thousand years, Green Tea has been enjoyed in the Orient, not only for its taste, but also as a health tonic. Upon analysis, it contains several strong antioxidants, called Polyphenols, with exceptional free radical scavenging abilities. Polyphenols have been shown to be over 200 times more effective than vitamin E in preventing oxidative damage to brain cells. Source Naturals uses a potent extract of green tea that concentrates 2,000 pounds of fresh green tea leaves into one pound of finished product. This extract has been awarded 30 patents for its protective effects. The ancient Ginkgo Biloba tree has long been prized for its beneficial qualities. Like proanthocyanidins, ginkgo’s compounds are able to cross the Blood-Brain Barrier, and support cell membrane and capillary integrity. Its particular antioxidant constituents have been associated with superior oxygen transport to the brain. This is important because the brain uses 20% of all inhaled oxygen. Source Naturals PYCNOGENOL® COMPLEX uses a superior 50 to 1 extract, providing 24% Ginkgoflavoneglycosides and 6% Terpenoids. Bilberries were first studied for their capacity to heighten visual acuity in normal subjects under poor light conditions. In fact, to increase their night vision, RAF pilots ate bilberry jam during WW II. Its antioxidant compounds, Anthocyanosides, have an affinity for delicate eye tissues, where it quenches free radicals and supports capillary strength. Source Naturals utilizes a standardized bilberry extract with 25% anthocyanosides, 80 times more potent than regular bilberry.

The wide range of natural antioxidants in Source Naturals PYCNOGENOL® COMPLEX

Milk Thistle Seed Extract has been researched and used for over 20 years in Europe. Its antioxidant compound, called Silymarin, has a special preference for the liver. It’s one of the few nutrients that can support the liver’s natural regenerative processes. By enhancing DNA activity, liver cells can regenerate up to five times faster. Turmeric Extract contains 95% Curcumin, the active ingredient of this traditional East Indian spice. Curcumin promotes the body’s own production of antioxidant enzymes, including glutathione peroxidase, an important protector of the liver. Curcumin also increases the production and secretion of bile, which is used to remove cholesterol from the body. Quercetin has been well-researched for its free radical scavenging activity. Because of its ability to stabilize cell membranes, quercetin helps prevent damage and discomfort from reactionary (histamine- and leukotriene-related) processes in the body. Source Naturals quercetin has been isolated from plant sources. Rosemary and Hawthorn Berries both contain bioflavonoid antioxidants that have the unique ability to neutralize the hydroxyl radical, a particularly dangerous type of free radical. Hydroxyls are produced by exposure to excessive radiation and pollution from burned fossil fuels. The body has no innate defense system against it. Vitamin C is one of the most active and abundant antioxidants in the body, so it must be frequently replenished. Since it works in conjunction with bioflavonoids, each tablet of Source Naturals PYCNOGENOL® COMPLEX contains 500 mg of vitamin C, bound to Magnesium for increased bioavailability.

A World of Help

As we better understand how free radicals affect our health and well being, it’s important that we take advantage of the wonderful protective qualities found in certain plants. These Plantioxidants provide the appropriate means to counteract the destructive effects of excessive free radicals, which have become part and parcel of modern life. Source Naturals PYCNOGENOL® COMPLEX brings the diverse and concentrated power of the plant world into your world of wellness.

References
• Masquelier, J. Natural Products as Medicinal Agents . Stutgart, Germany: Hippokrates Verlag, 1981. • Middleton, E. Jrnl. of Immunology 127 (1981): 546-50. • Muzes, G., et al. Acta-Physiologica-Hungary, 78.1 (1991): 3-9. • Oguni, I., et al. Orig. Res., Univ. of Shizuoka, Japan, 1990. PYCNOGENOL® is a registered trademark of Horphag Research, Ltd. Protected by U.S. Patent No. 4,698,360.

--
VitaNet ®
VitaNet ® Staff

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=189)

Date: June 02, 2005 12:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Heart Science - A Five-Tiered Approach to Heart Health ...

Heart Science 30 tabs

Your heart is crucial to every function of your body. It is the sole organ which pumps oxygen-rich blood through the entire circulatory system, feeding your cells and making life possible. Only recently are Americans realizing the importance of a proper low-fat diet, regular exercise, giving up cigarette smoking, and cutting down alcohol consumption to maintaining a healthy heart. Unfortunately, there has been a huge gap in the number of nutritional supplements which provide nutrients and herbs to support normal heart function. That’s where Source Naturals HEART SCIENCE comes in. Two years in the making, and backed by numerous scientific studies, the nutrients in HEART SCIENCE are some of the most soundly researched of all. Combining high potencies of these super-nutrients, HEART SCIENCE is the most comprehensive, cutting edge nutritional approach to proper heart care available.

Source Naturals HEART SCIENCE— The Five Tiered Approach to Heart Health

Your heart never rests. Even while you sleep, your heart must keep working, relying on the constant generation of energy by the body for its very survival. If this vital organ stops beating for even a short amount of time, all bodily functions cease and life ends. Source Naturals HEART SCIENCE helps support heart function on the chemical, cellular, structural, and energetic levels. This broad spectrum formula includes ingredients specifically geared for
1) generating energy,
2) decreasing harmful homocysteine levels,
3) fighting oxidized cholesterol,
4) maintaining the heart’s electrical rhythm, and
5) protecting artery and capillary linings.

Energy Generators for An Energetic Organ

Every day, the human heart beats about 104,000 times, pumping over 8,000 liters of blood through the body! Because it requires so much energy to perform efficiently, the experts at Source Naturals included specialty nutrients in HEART SCIENCE such as Coenzyme Q10 and L-Carnitine — integral factors in the body’s energy production cycles — to enhance the body’s energy supply.

There are three main interconnected energy generating cycles in our cells — the Glycolytic (sugar-burning) cycle, the Krebs’ (citric acid) cycle, and the Electron Transport Chain. Together they supply about 90 to 95% of our body’s entire energy supply, using fats, sugars, and amino acids as fuel. Coenzyme Q10 is one of the non-vitamin nutrients needed to maximally convert food into ATP (the energy producing molecule). It is the vital connecting link for three of the four main enzyme complexes in the Electron Transport Chain, the next step in energy generation after the Krebs’ cycle. Using the raw materials generated by the Krebs’ cycle, the Electron Transport Chain produces most of the body’s total energy! The heart is one of the bodily organs which contains the highest levels of CoQ10, precisely because it needs so much energy to function efficiently.

CoQ10 is one of the most promising nutrients for the heart under investigation today. It has been postulated that as a result of its participation in energy production, CoQ10 improves heart muscle metabolism and the electrical functioning of the heart by enhancing its pumping capacity.8 Many factors such as a high fat diet, lack of exercise, and cigarette smoking can lead to suboptimal functioning of the heart, and therefore failure of the heart to maintain adequate circulation of blood. Interestingly, people whose lifestyles reflect the above factors also tend to have depleted levels of CoQ10 in the heart muscle.10

Researchers suggest taking between 10-100 mg per day of CoQ10;18,29 HEART SCIENCE provides an impressive 60 mg of CoQ10 per 6 tablets. Similar to CoQ10, L-Carnitine is important for energy production in heart cells. It is a natural amino acid-like substance which plays a key role in transporting fatty acids, the heart’s main source of energy, to the mitochondria, the “power plants” of each cell, where they are utilized for the production of ATP. Heart and skeletal muscles are particularly vulnerable to L-Carnitine deficiency. Studies have shown that supplementation with LCarnitine improves exercise tolerance in individuals with suboptimal heart and circulatory function, and seems to lower blood lipid status and increase HDL (good) cholesterol.16, 22 Each daily dose of HEART SCIENCE contains 500 mg of this extremely important compound.

Like CoQ10 and L-Carnitine, B Vitamins help improve the ability of the heart muscle to function optimally. Each B Vitamin, after being converted to its active coenzyme form, acts as a catalytic “spark plug” for the body’s production of energy. Vitamin B-1, for example, is converted to Cocarboxylase, which serves as a critical link between the Glycolytic and Krebs’ Cycles, and also participates in the conversion of amino acids into energy. A deficiency of B coenzymes within contracting muscle cells can lead to a weakened pumping of the heart.21

HEART SCIENCE is formulated with high quantities of the most absorbable forms of B Vitamins providing maximum nutrition for the high energy demands of heart cells.

Homocysteine Regulators

B Vitamins also play a crucial role in the conversion of homocysteine, a group of potentially harmful amino acids produced by the body, to methionine, another more beneficial amino acid. While it is normal for the body to produce some homocysteine, even a small elevation in homocysteine levels can have negative implications. It is well documented that individuals who are genetically predisposed to having elevated homocysteine levels (homocysteinemics) tend to have excessive plaque accumulation in the arteries and premature damage to endothelial cells (cells lining the blood vessels and heart).26 Researchers have found that even those without this genetic abnormality, whose homocysteine levels are much lower than those of homocysteinemics, still have an increased risk for premature endothelial damage and the development of plaque in the arteries.24, 26 One study conducted among normal men and women found that those with the highest levels of homocysteine were twice as likely to have clogged arteries as were those with the lowest levels.24 Furthermore, it was found that the lower the research subjects’ blood levels of folate and B-6, the higher their homocysteine levels.24 Another study found that Folic Acid administered to normal men and women who were not even deficient in folate caused a significant reduction in plasma concentrations of homocysteine!3 In order to regulate homocysteine levels, it is critical to provide the body with sufficient amounts of B-6, B-12, and Folate, whether through the diet or through supplementation. HEART SCIENCE includes high levels of these three nutrients, providing B-6 in the regular and coenzyme form for maximum utilization.

The Dangers of Oxidized LDL Cholesterol

While many people have heard that high cholesterol levels may negatively affect normal heart function, few people understand exactly what cholesterol is, or how it can become harmful. Cholesterol is a white, waxy substance produced in the liver by all animals, and used for a variety of necessary activities in the body. Your liver also manufactures two main kinds of carrier molecules which transport cholesterol throughout the system: Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). Cholesterol is either carried out by LDL from the liver to all tissues in the body where it is deposited, or carried back by HDLs which remove cholesterol deposits from the arteries and carry them to the liver for disposal. Because of this, LDL cholesterol is considered damaging, while HDL is considered protective. Problems occur when there is too much LDL cholesterol in the body and not enough HDL.

When the body becomes overloaded with fat, an over-abundance of LDL particles are manufactured to process it, and they in turn become elevated in the body to a degree that the liver cannot handle. Rich in fatty acids and cholesterol, these particles are highly susceptible to free radical attack (oxidation). Once oxidized, LDL particles are no longer recognized by the body, which attacks them with immune cells. Immune cells which are bloated by oxidized lipids (called foam cells) are a key factor in the development of “fatty streaks” — the first sign of excess arterial fat accumulation. The bloated immune cells accumulate in artery lesions and create plaque in blood vessels, leading to obstruction and constriction of the vessels. Plus, these lodged foam cells continue to secrete free radicals into the bloodstream, making the problem worse.

The development of lesions in the arteries is not an uncommon problem. Arterial (and all blood vessel) walls are composed of a chemical matrix which holds the endothelial cells in place. That endothelial layer is the first and most important line of defense in preventing large molecules, such as cholesterol and fat, from entering the vessel wall. This matrix is composed of proteins, collagen, elastin, and glycosaminoglycans (amino sugars). Arterial lesions can be caused by suboptimal collagen and elastin synthesis due to three factors: 1. Vitamin C deficiency (since Vitamin C is a key building block for collagen and elastin); 2. excessive consumption of rancid fats, or heavy usage of alcohol or cigarettes; and 3. free radical damage. Once these lesions are created, the body attempts to repair them by depositing LDL cholesterol — similar to the way one would patch a tire. If that cholesterol is not oxidized, i.e. chemically changed to a harmful, unstable molecule, then this process does not create a problem. But when arterial lesions are “patched” with foam cells, arterial walls suffer page 3 page 4 even more damage, because those foam cells release free radicals which can further damage cell membranes.

Unfortunately, most people have a lot of oxidized cholesterol floating through the bloodstream. The typical American diet, with its low antioxidant intake and overconsumption of fried and overcooked foods, contributes to the overall levels of harmful oxidized cholesterol. In fact, the average American intake of antioxidants is low even by USRDA standards, making Americans particularly prone to having high levels of oxidized cholesterol.

Cholesterol Fighters

Fortunately, there are concrete steps you can take to prevent the oxidation of cholesterol, and its subsequent ill effects on health. In addition to cutting out high-cholesterol and fatty foods, supplementation can protect existing cholesterol and all tissue cells — from oxidation. Antioxidants, substances which scavenge and neutralize free radicals, protect the cardiovascular system by halting the oxidation of cholesterol, and helping to prevent plaque accumulation in the arteries and the continual secretion of free radicals by foam cells. Supplementing the diet with high amounts of Vitamin C, a key antioxidant, also encourages a more healthy “patching” of existing lesions by using collagen (made from Vitamin C) instead of cholesterol. HEART SCIENCE contains generous amounts of the following antioxidants for their protective benefits:

The Regulating Trio

Three nutrients — Magnesium, Potassium, and Taurine — work closely together in the body to help maintain the normal electrical rhythm of the heart, promote proper fluid balance, and prevent excessive Calcium levels from building up in the heart and artery linings.

Artery Lining Protectors

Your arteries form an integral part of your cardiovascular system, carrying blood away from the heart to nourish other parts of the body. In a healthy heart, blood surges through the arteries with every beat of the heart. The arteries expand with each pulse to accommodate the flow of blood. When arteries become hardened and narrowed by the build-up of plaque, they can’t expand and are not able to transport blood efficiently throughout the body. This inability to open up increases blood pressure, putting a strain on the heart as well as the arteries. HEART SCIENCE includes ingredients specifically geared to protect against plaque formation within arteries and maintain the flexibility of these vital blood vessels. N-Acetyl Glucosamine (NAG) is a key amino sugar which forms the building blocks of mucopolysaccharides. Mucopolysaccharides, which are long chain sugars, are an integral component of connective tissue. They combine to form gel-like matrixes which are present throughout tissues in the body, helping to maintain the elasticity of blood vessels which must continually adapt to the changing pressures of blood flow. Each daily dose of HEART SCIENCE provides 500 mg — a substantial amount — of this vital tissue building block. There is evidence indicating that Silicon, a natural mineral, may protect against plaque formation in the arteries. Silicon is found mainly in connective tissues, where it helps bind the body’s chemical matrix. Bound Silicon is found in high amounts in arterial walls. Researchers have found that there is a steady decline in the Silicon content of the aorta and other arteries as we age. This may be due to the low fiber content of the typical American diet, since fiber is a key dietary source of Silicon.23 HEART SCIENCE includes 400 mg of Horsetail herb extract, a natural source of Silicon. Hawthorn Berry is without question the herb most widely used to encourage normal heart function. The beneficial actions of Hawthorn Berry on cardiac function have been repeatedly demonstrated in experimental studies. Supplementation with Hawthorn Berry has been shown to improve both the blood supply to the heart by dilating coronary vessels, and the metabolic processes in the heart, resulting in normal, strong contractions of the heart muscle.34 Also, Hawthorn may inhibit the angiotensen converting enzyme, which is responsible for converting angiotensen I to angiotensen II, a powerful constrictor of blood vessels.34 Bromelain, a natural enzyme derived from pineapples, has become well-known for its neuromuscular relaxing properties. Researchers have reported favorable results when using Bromelain for soothing vascular linings. Initial research also indicates that Bromelain may break down fibrin, the glue which holds platelets together to form blood clots.6

Capillary Strengtheners

Capillaries are the smallest, yet some of the most important, blood vessels. If you think of your cardiovascular system as a series of roads which transport blood and oxygen, then your arteries are akin to interstate highways, your arterioles are the main city boulevards, and your capillaries are local residential streets. Capillaries are so small, in fact, that single red blood cells actually have to fold up to fit through them. Because of their tiny size and the intricate nature of their network throughout the body, capillaries are responsible for actually nourishing each individual tissue cell! Along the length of the capillaries are small openings called slit pores through which oxygen, glucose, and nutrients leave the capillaries and enter the surrounding interstitial fluid. From there, they cross cell membranes and nourish the cells. Similarly, the waste products of cells enter the fluid and cross over into the capillaries, where they are then transported to the liver and kidneys for disposal. If the capillary slit pores are torn or have lesions, then blood proteins and Sodium will leak out and cause the interstitial fluid to take on a more gel-like nature. This makes the transfer of oxygen and nutrients to the cells more difficult, as well as the disposal of cell waste products, turning the fluid into a stagnant swamp instead of a flowing river. In addition to its powerful antioxidant actions, Proanthodyn also helps protect collagen and elastin, the main constituents of tissue in the capillaries, and throughout the body. It is absolutely essential for capillary walls — which are only one cell thick — to be strong and stable, so that they do not allow blood proteins to leak into the interstitial fluid. Once the interstitial fluid takes on a gel-like consistency, the surrounding cells literally become starved from lack of nutrition. The exciting news is that the proanthocyanidins contained in Proanthodyn are among the few substances yet discovered which can help strengthen capillary walls, ensuring the liquid nature of the interstitial fluid.2 Plus, proanthocyanidins help keep capillary and artery walls flexible, allowing for proper blood flow to the heart.

Heart Smarts

The 1990’s mark a decade of increased awareness among Americans of important health issues. Much of the discussion has revolved around protecting that precious center of life we call the heart. Simple lifestyle change is one of the most effective ways to maintain and protect the functioning of the cardiovascular system. In order to take a holistic approach to heart care, make sure you include plenty of fresh fruits and vegetables (organic, if possible) in your diet, and cut down on fatty and cholesterol-forming foods. Reduce your salt and alcohol intake to a minimum. Try to get regular, sustained aerobic exercise for at least 30 minutes three times a week. Don’t smoke – or if you do smoke, try to eat even more fresh fruits and antioxidant-rich vegetables to counter the amount of free radicals being produced in your body. Lastly, consider adding Source Naturals HEART SCIENCE to your health regimen. HEART SCIENCE, the most comprehensive formula of its kind, provides targeted protection to the entire cardiovascular system. By approaching the promotion of normal heart function on five different levels — through the inclusion of ingredients which supply energy, decrease harmful homocysteine levels, fight cholesterol build-up, help regulate electrical rhythm, and protect artery and capillary linings — HEART SCIENCE is the perfect addition to a holistic approach to heart care.

Source Naturals HEART SCIENCE™

The Five Tiered Approach to Heart Health
Six tablets contain:
Vitamins and Minerals %USRDA
Pro-Vit A (Beta Carotene) 45,000 IU 900%
Vit B1 (Thiamine) 50 mg 3333%
Vit B3 (Inositol Hexanicotinate) 500 mg 2500%
Vit B6 (Pyridoxine HCl) 25 mg 1250%
Coenzyme B6 (Pyridoxal-5-Phosphate)
25 mg yielding: 16.9 mg of Vit B6 845% (Total Vitamin B6 Activity) (41.9 mg) (2095%)
Vit B12 (Cyanocobalamin) 500 mcg 8333%
Folic Acid 800 mcg 200%
Vit C (Magnesium Ascorbate) 1500 mg 2500%
Vit E (d-alpha Tocopheryl Succinate) 400 IU 1333%
Chromium (ChromeMate® †Polynicotinate-150 mcg & Chromium Picolinate††-150 mcg) 300 mcg *
Copper (Sebacate) 750 mcg 37.5%
Magnesium (Ascorbate, Taurinate & Oxide) 300 mg 75%
Potassium (Citrate) 99 mg *
Selenium (L-Selenomethionine) 200 mcg *
Silicon (From 400 mg of Horsetail Extract) 13mg *
* U.S. RDA not established.
Other Ingredients and Herbs
Coenzyme Q10 (Ubiquinone) 60 mg
L-Carnitine (L-Tartrate) 500 mg
Hawthorn Berry Extract 400 mg
Proanthodyn™ (Yielding 95 mg of Proanthocyanidins from grape seed extract) 100 mg
L-Proline 500 mg
L-Lysine (HCl) 500 mg
NAG™ (N-Acetyl Glucosamine) 500 mg
Bromelain (2000 G.D.U. per gram) 1200 G.D.U.
Taurine (Magnesium Taurinate) 500 mg
Horsetail Extract (Yielding 31 mg of Silica) 400 mg
Inositol (Hexanicotinate) 50 mg

Reference:
1. Azuma, J., Sawamura, A., & Awata, N. (1992, Jan). “Usefulness of Taurine... and its Prospective Application.” Japanese Circulation Journal, 56(1), 95-9.
2. Blazso, G and Gabor, M. (1980). “Odema-inhibiting Effect of Procyanidin.” Acta Physiologica Academiae ScientiarumHungaricae, 56(2), 235-240.
3. Brattstrom, E. L, Hultberg, L. B., & Hardebo, E. J. (1985, Nov.). “Folic Acid Responsive Postmenopausal Homocysteinemia.” Metabolism, (34)11, 1073-1077.
4. Colette, C., et al., (1988). “Platelet Function in Type I Diabetes: Effects of Supplementation with Large Doses of Vitamin E.” American Journal of Clinical Nutrition, 47, 256-61.
5. England, M. R., et al. (1992, Nov. 4). “Magnesium Administration and Dysrhythmias...A Placebo-controlled, Double-blind, Randomized Trial.” Journal of the American Medical Association, 268(17), 2395-402.
6. Felton, G. E. (1980, Nov.). “Fibrinolytic and Antithrombotic Action of Bromelain...” Medical Hypotheses (11)6, 1123-33.
7. Grundy, S. M. (1993, Apr.). “Oxidized LDL and Atherogenesis: Relation to Risk Factors...” Clinical Cardiology, 16 (4 Suppl.I), I3-5.
8. Hano, O. et al. (1994, June). “Coenzyme Q10 Enhances Cardiac Functional and Metabolic Recovery and Reduces Ca2+ Overload during Postischemic Reperfusion.” American Journal of Physiology, 266(6 Pt 2), H2174-81.
9. Heineke, et al. (1972). “Effect of Bromelain (Ananase) on Human Platelet Aggregation.” Experientia V. 23, 844-45.
10. Hendler, S. S. (1991). The Doctors’ Vitamin and Mineral Encyclopedia. NewYork: Fireside.
11. Jandak, et al. (1988, Dec. 15). “Reduction of Platelet Adhesiveness by Vitamin E Supplementation in Humans.” Thrombosis Research 49(4), 393-404.
12. Jialal, I., et al. (1991, Oct. 15). “Beta-Carotene Inhibits the Oxidative Modification of Low-density Lipoprotein.” Biochimica et Biophysica Acta, 1086(1), 134-8.
13. Jialal, I. & Fuller, C. J. (1993, Apr. 16). “Oxidized LDL and Antioxidants.” Clinical Cardiology, Vol. 16 (Suppl. I), I6-9.
14. Jialal, I., & Grundy, S.M. (1991, Feb.). “Preservation of the Endogenous Antioxidants in Low Density Lipoprotein...” Journal of Clinical Investigation, 87(2), 597-601.
15. Kamikawa, T., et al. (1985). “Effects of Coenzyme Q10 on Exercise Tolerance...” American Journal of Cardiology, 56, 247-251.
16. Kosolcharoen, P., et al. (1981, Nov.). “Improved Exercise Tolerance after Administration of Carnitine.” Current Therapeutic Research, 753-764.
17. Lawn, R. (1992, June). “Lipoprotein (a) in ...” Medicine, 12-18.
18. Mortensen, S.A.et al. (1985). “Long-term coenzyme Q10 therapy: A major advance in the management of resistant myocardial failure.” Drugs Exp. Clin. Res., 11(8), 581-93.
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VitaNet ®
VitaNet ® Staff

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=155)

Date: June 01, 2005 09:59 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CAT’S CLAW DEFENSE COMPLEX - Health Secrets from the Rainforest

CAT’S CLAW DEFENSE COMPLEX

Standard pharmaceutical drugs came into common use only around the turn of the century. Before that, herbal preparations were administered for health concerns. Today, in nearly every country in the world, herbs are used by health care practitioners as the focal point of health care. Only in the United States is the otherwise widespread use of herbs missing in mainstream culture. But now modern scientific investigation is confirming the benefits of herbal supplementation, which is paving the way for us to reclaim and implement herbs into our everyday lives.

The primary need for preserving the rainforests

Rain Forest Herbs

Scientists’ knowledge of the varied rain forest flora is far from complete. The plants which have been thus far identified are so elaborate in molecular structure that it’s difficult to understand how these molecules function, let alone how to reproduce them. What is known is that the biodiversity of the rain forest yields numerous biologically active plant constituents which can have a profound influence on supporting the body through times of imbalance. Preserving the rain forest means preserving these precious herbs and the unique constituents contained within them.

Cat’s Claw Defense Complex contains powerful rainforest herbs

A Synergistic Blend

Source Naturals CAT’S CLAW DEFENSE COMPLEX harnesses the power of some of the most complex botanicals on earth into a synergistic blend of defense-enhancing herbs, each with a unique set of compounds which complement the body’s natural physiology. Source Naturals CAT’S CLAW DEFENSE COMPLEX is the first step in the rediscovery of a long-standing herbal tradition. Source Naturals was the first full-line supplement company to introduce the herbal superstar, Cat’s Claw, and the first to offer it in a combination formula. CAT’S CLAW DEFENSE COMPLEX provides 2000 mg of Cat’s Claw per four tablets – more than many companies’ single ingredient Cat’s Claw products! It combines powerful rain forest herbs like Pau D’Arco and Western herbs such as Aloe Vera and St. John’s Wort with legendary Chinese herbs (Reishi Mushroom and Astragalus). Source Naturals Cat’s Claw Defense Complex also includes two categories of antioxidants for broad spectrum support.

How we ensure quality and potency

Cat’s Claw & Pau D’Arco – Peruvian Jungle Discoveries

Cat’s Claw was discovered in the depths of the Peruvian Amazon jungle. Researchers have discovered that components extracted from the herb can bolster the body’s innate defenses, address discomforts associated with stress, and support intestinal health. Source Naturals uses only the highest quality Cat’s Claw inner bark – which is at least twenty years old, the amount of time it takes the bark to reach its peak biological activity– and uses a careful process to insure that harvesting the bark doesn’t weaken or destroy the plant. Like all of our herbs, each shipment of Cat’s Claw is also routinely inspected and tested by a trained herbalist to ensure maximum quality and potency. Pau D’Arco is also native to the South American rain forest and, like Cat’s Claw, has a high concentration of active constituents – a combination of anthraquinones and naphthoquinones, primarily lapachol – in the bark of the plant. Each daily dosage of CAT’S CLAW DEFENSE COMPLEX contains 100 mg of Pau D’Arco bark and 100 mg of concentrated Pau D’Arco bark extract for broad spectrum support.

Herbs — Adaptogens for Balance

Of the Chinese herbs, Siberian Ginseng is one of the best known adaptogens. Adaptogens have a balancing effect, helping us adapt to increased stress levels and other changes, like different altitudes or time zones. Thus, supplementation with Siberian Ginseng can help prevent stress-related health concerns. Schizandra, a small creeping vine with red berries, is a Chinese adaptogen which helps regulate the body’s functions and cleanse it of toxins.

Herbs that energize the body and build resistance to impaired bodily function

The trio of Chinese mushrooms – Reishi, Shiitake, and Maitake – has been used by Chinese herbalists for centuries, and provides the highest quality natural support for the body’s defenses. Modern science has revealed the true power behind Reishi, Shiitake, and Maitake: high levels of polysaccharides – long chain sugar macromolecules which are known for their protective and cleansing abilities. CAT’S CLAW DEFENSE COMPLEX utilizes only the mycelia biomass of Reishi (200 mg), Shiitake (200 mg), and Maitake (150 mg) to ensure the highest level of activity. Astragalus is the premier tonic – or internal strengthener – of Chinese herbalism. In addition to helping energize the body, Astragalus also builds resistance to weakness and to impaired bodily function. Isatis is a cooling herb which has been shown to have a broad spectrum inhibitory action in in-vitro studies, and helps support normal liver function. Used for thousands of years, the aloe plant has been treasured for its varied uses both externally and internally. Aloe Vera juice is high in mucopolysaccharides, which have been found to have powerful protective capabilities. CAT’S CLAW DEFENSE COMPLEX provides 200 mg of aloe (200:1 concentration) extracted from the whole leaf of the plant.

Why St. John’s Wort is powerful and useful

It is generally agreed that hypericin and pseudohypericin, two bioflavonoids which are the active constituents in St. John’s Wort, probably act as monoamine oxidase (MAO) inhibitors, which current research has shown are powerful as internal cleansing agents. St. John’s Wort is particularly useful because of its ability to cross the Blood-Brain Barrier, through which many elements are unable to pass.

The liver’s health is essential because of its responsibility for over 500 different functions

Antioxidants and Plantioxidants – Supporting Complete Health

Source Naturals CAT’S CLAW DEFENSE COMPLEX includes key liver-supporting antioxidants like Zinc, Beta Carotene, and Vitamin C – nutrients that help protect the liver from stress and pollution induced free radical damage. These three nutrients are also wellknown for their ability to help strengthen the body’s resistance and move through imbalances quickly. The liver is responsible for over 500 functions, including converting vitamins to their active forms, and processing and eliminating waste products from the body; therefore its health is vital. Plantioxidants™ is Source Naturals’ term for Plant-Derived Antioxidant Bioflavonoids. Though most people are only aware of the vitamin and mineral antioxidants, the latest scientific research has indicated that the plant kingdom may provide the most potent antioxidants in the world. Plants, trees, and citrus fruits all contain bioflavonoids (also called polyphenols) – a large group of restorative compounds with similar chemical structures which help protect the body from the ravages of oxidative damage due to free radicals. Some of the Plantioxidants included in CAT’S CLAW DEFENSE COMPLEX are: Quercetin, which helps inhibit the body’s sensitivity to dangerous particles in the air; Proanthodyn, which promotes tissue repair by helping to strengthen collagen and elastin, the two primary structural components in cartilage; Silymarin, which promotes liver-tissue regeneration and optimizes liver-cell function; Green Tea, a remarkably potent antioxidant; and Ginkgo, which is renowned for helping transport oxygen to the brain.

The way to naturally bolster the body’s defenses

A Holistic Natural Answer

The natural world provides us with a seemingly endless supply of complex herbal compounds with unreplicable and unique constituents so varied and numerous that most doctors aren’t even aware of their existence. Source Naturals would like to change that with CAT’S CLAW DEFENSE COMPLEX – the natural way to bolster the body’s innate defenses. All the ingredients included are at optimal potencies, and in the forms best absorbed by the body. The result? The most powerful, holistic product available to help maintain the structure and function of the natural defenses – Source Naturals CAT’S CLAW DEFENSE COMPLEX.

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VitaNet ®
VitaNet ® Staff

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=130)

Date: June 01, 2005 09:15 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Bioflavonoid Complex - Botanical Antioxidant Protection

Bioflavonoid Complex

Specialty Bioflavonoids

Bioflavonoids occur as pigments in plants, where they are found in close association with vitamin C. Together, bioflavonoids and C provide antioxidant protection, helping plants withstand harsh environmental conditions. BIOFLAVONOID COMPLEX features potent botanical extracts, many of them standardized to specific beneficial constituents. Included are bilberry, ginkgo biloba, grape seed, green tea, hawthorn berry, quercetin, and silymarin. The formula is enhanced by the addition of vitamin C as highly bioavailable magnesium ascorbate.