|
Search Term: " over-simulae "
GABA   
Date:
August 26, 2008 04:58 PM
GABA is gama amino butyric acid, and is an inhibitory neurotransmitter that is essential for the proper function of your brain and the central nervous system, and has the effect of reducing excessive brain activity and promoting a state of calm. For many people, the rush of daily life, with its problems, worries and external stimuli, can over-stimulate the brain to the extent that it can all seem too much for them. They feel anxious and overwhelmed, and wish that they could just go into a quiet corner to get away from it all. Most people have felt like that at some time, but the demands of life do not allow them that luxury. They just have to bear it and get on with life. That is where GABA can come in. It can be used to bring your nervous system back to base, and make you feel more relaxed, calmer and more able to meet these challenges that life often throws at you. When you feel that you just can’t relax or concentrate on what you are doing, GABA can help you. If you look around you and everybody else seems OK, without apparently feeling the stress and irritability that you feel, and then perhaps your problem is due to a GABA deficiency. GABA is the principal inhibitory neurotransmitter in your brain, and a deficiency would certainly give you the symptoms that you are feeling. Let me explain why. As your brain becomes excited, it can run out of control and needs some form of modification or inhibition to keep it acting as normal. Without this you would become increasingly more restless and irritable, and ultimately have seizures. GABA is not only the main inhibitor in your brain, but also helps in the production of endorphins that provide you with a sense of well being. That sense of calm you feel when endorphins are produced, for example during exercise or sexual intercourse, is commonly referred to as the ‘endorphin effect’. GABA is at its highest concentration in specific areas of the brain, including the hypothalamus, the hippocampus and the central brain area, and is present in up to 40% of all synapses, the small gaps between neurons across which brain cells can communicate with each other. It is produced during the Krebs or Citric Acid Cycle that is responsible for cell respiration or the production of energy from carbohydrates. It is synthesized from alpha-keto glutarate, which is produced just before the Succinyl Co-A stage of the Krebs Cycle in the brain. Vitamin B6 in involved in its metabolism, and a Vitamin B6 deficiency can lead to a deficiency in GABA that might result in seizures. Basically GABA works by inhibiting the firing of neurons in your brain, and thus reducing general brain activity. The GABA receptor allows more chloride ion to enter the brain cell, thus helping to maintain the electrical charge within the cells. Bezodiazepines (e.g. diazepam) work by increasing the effectiveness of GABA in opening the chloride ion cells to allow more chloride ion to enter the neurons, and caffeine does the opposite, and inhibits this property of GABA. Thus diazepam works as a minor tranquilizer and caffeine as a stimulant. Alcohol has a similar effect to the benzodiazepines, increasing the release of chloride into the neurons, and is the major way in which alcohol affects the brain. In fact, tolerance to drugs and withdrawal symptoms can be explained by the receptors adapting to the drug. They may increase in number, which means that more of the drug is needed to work on them, and they can become hypoactive in the event of the drug being withdrawn, that enhances the symptoms that the drug was intended to treat. So basically, that is the way that GABA works. In simple terms it increases the flow of chloride electrolyte to the brain, and in so doing affects our mood. This effect is enhanced by prescription drugs such as Valium and Ativan, which are used by those that suffer the effects of a GABA deficiency. However, these drugs have side effects, not the least of which is dependency due to the GABA receptors becoming modified to suit the drug. There is a more natural way to overcome many stress problems and symptoms of mood swings. Knowing what causes these symptoms, it makes sense to eat foods that stimulate the creation of neurotransmitters to replace those that are deficient. Since GABA is produced in the Krebs Cycle and complex carbohydrates produce glutamine that is an important part of that Cycle, and is also the precursor to GABA, then the consumption of such foods should in theory produce more GABA. In this case the theory works, and you should eat foods rich in complex carbohydrates such as whole grains, brown rice and oats as part of your diet. Other foods that are high in glutamine or its precursors, glutamic acid and glutamate, include citrus fruits, beef liver, broccoli, halibut and lentils. A useful supplement to take is L-theanine, an amino acid found in green tea, and available in supplement form. L-theanine can calm your nerves while maintaining clarity of thought. In other words it calms you down, but doesn’t make you drowsy and allows you to enjoy your day with anxiety. Your doctor can determine whether or not you have a neurotransmitter deficiency through a simple urine test, and might also test your saliva for hormone content. A GABA supplement might be indicated, and if so it other beneficial effects on your body other than its effect on your brain cells. It improves your sleep cycles and promotes vivid dreaming, and can also have a positive effect on your blood pressure. It is also an effective pain killer, and can provide relief from such conditions as back pain and arthritis. Its stimulating effect on the anterior pituitary gland to secrete Human Growth Hormone might also be regarded as a benefit by many. Increasing the level of HGH in your blood can lead to fat loss and improved anabolic activity (increase in muscle tissue). This can be of benefit to older people whose level of HGH secretion has dropped off, and who find it more difficult to lose fat. GABA is a substance that has many known benefits and no known side effects other than a slight tingling and increase in heart rate when the supplement is first used. It has a definite benefit for people to whom the world seems too hectic and overwhelming.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1875) Adapt To The Stresses Of Life with Herbal Adaptogens 
Date:
October 18, 2007 11:13 AM
Life today places a number of different types of stresses upon us. There are the normal stresses of living, of facing problems at work, financial worries and family stresses. Schedules are becoming busier as we try to pack more and more into each day, and relaxation time is cut to a minimum. For many of us, the stress starts when we waken and rush through breakfast, if we have time for one, to catch the bus or train to work, or to slip into the morning traffic rush that takes us an hour to travel 10 miles or less. Once at work we have problems to deal with that continue throughout a rushed lunch period, and then back to the stress of trying to return home in the evening to open the bills and check if we have enough in the bank to pay them. However, that is not all. Our environment is continually changing, and our bodies are subject to the stresses of pollution from the planes, trains and automobiles, not to mention the pesticides, preservatives plastics and harsh lighting. The noise of air conditioning and the continual musak of the stores and shopping malls and everything else that goes to completely stress us out, weekdays and weekends. That is ignoring the smog, the disappearing ozone layer and increased UV radiation, the greenhouse effect and global warming, El Nino and everything else that causes worry or affects the delicate balance of the body’s biochemistry. Rather than adapting to our environment we are continually striving to adapt the environment to suit our needs. We should develop a flexibility of mind and body so that we can survive these modern-day stresses, and this is where the substances known as adaptogens are important. Adaptogens help us to adapt to the environment and withstand the stresses of modern life. The term was first used by Russian N.V. Lazarev in 1947 who defined an adaptogen as a substance meeting three specific criteria: it should cause a minimal disruption to the normal physiological function of the body, it must work by means of a range of chemical, physical and biochemical factors rather than through one specific action and must have an overall effect of normalization, so that no condition is aggravated to improve another. There are a large number of identified adaptogens, among them several forms of ginseng: Panax, American, Siberian and Japanese; licorice, schizandra berries, rhodiola and others. These adaptogens tend to work in the body by improving the body’s availability and use of energy, improving the efficiency of removal of the metabolic waste and by-products, supporting the adrenal function so that the effects of stress are reduced or countered, improving the utilization of oxygen and helping to build up body tissue. In general the body works more efficiently in generating and using energy, muscle tissue and counteracting the effects of modern day stress, both environmental and psychological. Of the ginsengs, Panax is very expensive for regular use, although many people prefer it. However, studies have shown that Siberian, or eleuthero ginseng, is a stronger adaptogen that Panax which is also called Korean or Chinese ginseng. In fact the other forms, including American and Japanese, tend to over-stimulate the body, and can also cause unwanted side effects such as constipation and over-excitement. The Siberian ginseng tends not to show these symptoms. Siberian ginseng contains seven active substances known as eleutherosides A – F which are not present in the other ginsengs. These substances appear to have several properties that have been clinically proven. For example, they relieve insomnia, one of the symptoms of stress, high and low blood pressure, bronchitis, various forms of neuroses and, it is claimed, also some types of cancer. Siberian ginseng also allows humans to withstand noise, heat and extra stresses caused by severe workloads. It improves athletic performance and allows people to improve their work output under a variety of stresses. Athletes can train harder and recover quicker. Another adaptogen is schizandra berries (also called schizandra chinensis and magnolia vine). Chinese herbalists class medicinal herbs by the five different flavors, sour, bitter, salty, acrid and sweet. Schizandra berries possess all five, and are therefore considered by the Chinese to balance all the systems of the body. It is used in the West as a stress reducing adaptogen and is also included in sports and weight loss formulae. It helps insomnia and improves endurance and mental coordination. Schizandra is believed to be a good tonic for the liver and is often used in combination with Siberian ginseng (eleuthero) and licorice. The latter is another popular herb in China that is said to be a good tonic for the spleen. Licorice itself is a known anti-inflammatory since it contains flavanoids and saponins that promote the immune system. Licorice is thought be a useful supplement for HIV patients due to its effect on the immune system. It also increases corticosteroid levels by inhibiting the liver’s ability to break down adrenal hormone. However, people with high blood pressure should be careful with licorice since it can cause sodium retention. Like any other medication, you should seek your physician’s advice if you have any existing conditions. Rhodiola, also referred as roseroot, is used for improved memory and enhanced vitality and it can also be used as a mood modifier. It is used by athletes of all types for increased strength and endurance, and improved cardiovascular and muscle recovery time. The Russians call it ‘Golden Root’ and it is a safe and effective adaptogen. More and more people are turning to adaptogens to help them cope with the hustle and bustle of their daily lives, and they are becoming increasingly available from ordinary health stores. If you are finding it difficult to stay energetic and active then try them out. Not all work with every individual, but there is a large variety to choose from and most people are able to find an adaptogen that suits them and enables them to adapt to the stresses of daily life.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1596) Takeing Cat's Claw, IP-6 and Maitake Mushroom over stimulate immune system?
Date:
November 11, 2005 06:33 PM
Q. If these three natural products are taken together, could they over-stimulate my immune system? A. That is a very good question. And at first glance, it might seem a possibility. However, one of the most amazing aspects of all three nutritional products, POA cat’s claw root extract, maitake d-fraction, and IP-6 with inositol, is their ability to both strengthen a weakened immune system and calm down a hyperactive immune system. They modulate the immune system. The POAs in cat’s claw root extract do not take over the immune system’s job, they simply strengthen the body’s immune system so it can do its job better. Maitake D-fraction does not act on cancer cells directly, it encourages the body’s own immune system regulators to act. IP-6 with inositol does not increase NK cells, it increases NK cell activity. In other words, these three natural discoveries strengthen and balance the immune system without the fear of over-stimulation.
In fact, it is theorized that cat’s claw root extract, maitake mushrooms, and IP-6 with inositol may work synergistically. Meaning, together they strengthen and balance the immune system even better when they are taken together. However, if you use a cat’s claw supplement that contains any amount of TOAs, not only will the good “spirits” of POAs be cancelled, experts believe that they will interfere with IP-6 with inositol as well. That’s why it is vital to choose a cat’s claw supplement that is 100% TOA-free and says so on its label.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=940) Echinacea - Choosing The Ideal Immune Support 
Date:
June 30, 2005 09:27 AM
Echinacea By Ellen J. Kamhi, Ph. D. with Dorie Greenblatt Echinacea, pronounced ek-i-NAY-see-a, is one herb that has become a “household” name in the 1990’s. Many refer to it as “Purple Cone Flower” because of its large purple daisy petals, which contain a hard and spiny center cone. These spines probably give the plant its name, since sea animals with spines are called “echinoderms”. Echinacea is indigenous to the U.S., and can be found both growing wild in many areas as well as in cultivated gardens. There are actually nine different species of the plant; two are most popular as remedies: Echinacea angustifolia and Echinacea purpurea. Echinacea has a long history of use by Native Americans, who have utilized the herb for a wide variety of treatments ranging from stings, poisoning, toothaches and swollen glands to colds and sore throats. It has also been touted as an ideal natural remedy for snake bites. In particular, the benefit of Echinacea as a treatment for snake bites brought national attention to the herb in the last half of the 1800’s. Dr. H.F.C. Meyer of Pawnee City, Nebraska first tried to interest Eclectic Physicians (doctors who used natural medicines) to use Echinacea as an herbal remedy for snake bites by volunteering to be bitten by a rattlesnake to prove its effectiveness. Although his dramatic offer was rejected, his enthusiasm and concerted efforts led to renewed interest and investigative studies on Echinacea, resulting in the herb’s emergence as one of the most popular natural plant therapies by the turn of the century. Extensive studies on Echinacea’s medicinal properties continue to mirror the earlier usages of the herb as experienced by indigenous people. In fact, Echinacea is part of the official materia medica listed in the German Commission E. Monographs, a universally recognized publication reputed to be the official information authority on herbal medicines. The Commission lists a number of medicinal applications for Echinacea as an ideal treatment for such conditions as colds, chronic infections of the respiratory tract and lower urinary tract ailments, as well as topically for chronic ulcerations and slow healing wounds. Echinacea has been shown to be a potent immune system stimulant. Nature’s Answer® offers an outstanding Echinacea fluid herbal extract formula in a unique blend that contains both Echinacea angustifolia root and Echinacea purpurea whole plant. Fluid extracts that feature both whole plant and root parts in the formula insure that the highest levels of the whole herb’s active constituents are maintained. A further advantage to this kind of supplement lies in its delivery system– liquids are faster to absorb and easier to assimilate by the body than tablets or capsules. Nature’s Answer®’s Echinacea formulas are available in either alcohol-free or organic alcohol forms. In addition, the alcohol-free supplements are also offered in a tasty grape or tangy orange flavor. Two popular blends featuring Echinacea with other supportive herbs are Immune Boost™ and Re-Zist™. Immune Boost™ combines Echinacea with Wild Indigo and Maitake Mushroom. Re-Zist™ contains Echinacea, Goldenseal, Wild Indigo, Cayenne and Myrrh for potent support. Echinacea is also recognized for its ability to enhance the resistance of cells to viruses, especially when used after cells have been exposed to colds and flus. As a preventative, formulas such as Nature’s Answer®’s Echinacea/Goldenseal (alcohol-free, organic alcohol) are ideal. This is an excellent supplement for soothing sore throats and helping to shrink swollen glands. An added benefit to the formula is the presence to berberine, the active ingredient in Goldenseal, which provides further wellness enhancement. Many studies have focused on Echinacea’s possible use for ailments such as psoriasis and early rheumatoid arthritis. The herb also acts as an overall anti-inflammatory tonic. Nature’s Answer®’s Blood Support™ (alcohol-free) combines Echinacea with Dandelion, Licorice and other herbs for an anti-inflammatory effect. Allertone™ (alcohol-free) blends Echinacea with Mullein Leaf to help support the respiratory and sinus areas. Most herbal practitioners suggest using Echinacea for short-term periods. There has been evidence to suggest that the herb loses its effectiveness when used over longer periods of time. Also, in the case of autoimmune illnesses, some people believe Echinacea may OVER-stimulate the immune system, although there is no solid research to back this contention. Echinacea is probably most effective if used in frequent doses for 5-7 days at the early onset of symptoms. It may also serve as a preventative during periods after known exposure or during extra stress, taking it two to three times a day every other or every third day. The German Commission E lists no known drug interactions or side effects with Echinacea. It is indeed one of the safest and most effective herbs for natural immune support today. Echinacea seems well suited to life in the 90’s with all the stresses upon our immune systems. Its importance and effectiveness as an immune stimulant is as true today as it was in 1927 when Dr. Liebstein stated: “Nature has probably destined Echinacea to be used for remedial purposes only, as a sustainer of vitality, an organizer of the defensive powers of the system, to such an extent as to be justly crowned the greatest immunizing agent in the entire vegetable kingdom....” written in 1927 by Dr. A. M. Liebstein (Foster, 1991)
-- Vitanet ®
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=539) | ||||||||||||||||||||||||||||
