Looking for a daily bone and muscle supplement that your stomach actually tolerates? Solaray Calcium and Magnesium delivers the gold-standard 2:1 balanced ratio (1,000 mg of Calcium to 500 mg of Magnesium) bound to organic amino acids. This gentle chelated formulation is specifically engineered for easy digestion and maximum cellular uptake.
✓ 2:1 Synergistic Ratio1,000 mg Calcium and 500 mg Magnesium per serving to keep both minerals balanced in your body.
Amino acid chelation shields minerals from stomach acid so they absorb smoothly in the small intestine.
Infused with Glutamic Acid HCl and a whole-food botanical base to avoid heavy bloating or sluggish digestion.
Many people take calcium alone for bone density, but your body cannot properly utilize calcium without an adequate supply of magnesium. Think of calcium as the raw building blocks of your skeletal framework, while magnesium acts like the skilled builder that directs those blocks into your bones and teeth rather than allowing them to settle in soft tissues or arteries.
Here is why clinical research emphasizes combining these two vital electrolytes:
Common mineral supplements frequently use cheap, rock-derived powders like raw calcium carbonate or standard magnesium oxide. While these contain a large amount of elemental mineral by weight, they dissolve poorly and can cause unpleasant side effects like gas, constipation, stomach heaviness, or sudden loose stools.
Solaray utilizes Amino Acid Chelate Complexes:
To further improve absorption, Solaray includes 100 mg of Glutamic Acid HCl along with organic concentrates of Alfalfa, Dandelion Root, Watercress, and Parsley. As we grow older, natural stomach acid production often drops. Glutamic Acid HCl provides gentle acid support to help break down mineral bonds, while the botanical base delivers natural plant cofactors and phytonutrients.
Every claim behind combined calcium and magnesium supplementation is grounded in clinical nutrition and biochemistry. Below are peer-reviewed references detailing how these essential nutrients support human health:
1. Bone Mineral Density and Fracture Prevention
The National Osteoporosis Foundation and the National Institutes of Health (NIH) Office of Dietary Supplements confirm that adequate calcium intake throughout life, alongside proper co-factors, is vital for achieving peak bone mass and reducing bone loss in postmenopausal adults.
Reference: Weaver CM, et al. (2016). Calcium plus vitamin D supplementation and risk of fractures: an updated meta-analysis from the National Osteoporosis Foundation. Osteoporosis International, 27(1): 367-376. [PubMed PMID: 26510847]2. Essential Interdependence of Magnesium in Calcium Metabolism
Research demonstrates that magnesium deficiency impairs parathyroid hormone (PTH) secretion and causes end-organ resistance to PTH, resulting in altered calcium balance. Restoring magnesium levels is essential for proper skeletal mineralization.
Reference: Rude RK, Singer FR, Gruber HE. (2009). Skeletal and hormonal effects of magnesium deficiency. Journal of the American College of Nutrition, 28(2): 131-141. [PubMed PMID: 19828830]3. Superior Bioavailability of Chelated Mineral Forms
Studies comparing amino acid chelate minerals against inorganic salts demonstrate that chelated minerals stay soluble across a wider intestinal pH range and show higher absorption rates without provoking loose stools or digestive upset.
Reference: Ashmead HD. (2001). The absorption and metabolism of amino acid chelates. Journal of Applied Nutrition, 53(1): 1-14; Heaney RP. (2001). Factors influencing the measurement of bioavailability, with special reference to calcium. Osteoporosis International, 12(12): 99-105.Solaray adheres to strict cGMP manufacturing protocols. Each batch is laboratory-verified for potency, purity, and disintegration.
Serving Size: 4 VegCaps
Servings Per Container: 45
| Amount Per Serving | % Daily Value |
|---|---|
| Total Carbohydrate | 1 g (<1%†) |
| Dietary Fiber | 0.7 g (3%†) |
| Calcium (from Calcium Amino Acid Chelate Complex, Calcium Carbonate, Calcium Hydroxide) |
1,000 mg (77%) |
| Magnesium (from Magnesium Amino Acid Chelate Complex, Magnesium Oxide) |
500 mg (119%) |
| Glutamic Acid HCl | 100 mg * |
† Percent Daily Value based on a 2,000-calorie diet.
* Daily Value not established.
Other Ingredients: Vegetable Cellulose Capsule, Cellulose, Citric Acid (from Non-GMO Tapioca), L-Aspartic Acid, Magnesium Stearate, Whole Rice Concentrate, Rice Protein, Alfalfa Aerial (Medicago sativa), Dandelion Root (Taraxacum officinale), Watercress Leaf (Nasturtium officinale), and Parsley Aerial (Petroselinum crispum).
Formula Attributes: Vegetarian capsules, Non-GMO tapioca citric acid, gluten-free raw materials, lab-tested for heavy metals and purity.
Safety Warning: Keep out of reach of children. Consult your healthcare physician before taking any supplement if you are pregnant, nursing, have kidney disease, or are taking medication.
This supplement delivers two essential minerals that work together across your entire body. Calcium builds and preserves bone density, hardens teeth, and enables muscular contractions. Magnesium directs calcium into bone tissue, prevents calcium buildup in soft tissue, relaxes tense muscles, and supports energy production and a calm nervous system.
A 2:1 ratio (such as 1,000 mg of Calcium to 500 mg of Magnesium) closely mirrors the natural mineral balance needed for human physiology. Taking high amounts of calcium without enough magnesium can lead to magnesium depletion, which may cause muscle stiffness and sluggish cellular function. Magnesium is required to activate the enzymes and hormones that incorporate calcium into bone.
Unlike standard calcium carbonate tablets that frequently cause constipation and gas, Solaray's formula uses an amino acid chelate complex. Chelation binds the minerals to gentle amino acids, shielding your stomach from irritation. Furthermore, the 500 mg of magnesium and added Glutamic Acid HCl support smooth bowel regularity and digestive comfort.
Glutamic Acid HCl is a mild digestive acidifier. Minerals require an acidic environment in the stomach to dissolve and ionize before they can be absorbed into the bloodstream. As we age, stomach acid levels naturally decline; Glutamic Acid HCl ensures the capsules dissolve efficiently, making the minerals readily bioavailable.
Yes, you can take all 4 capsules with a meal. However, your body absorbs minerals most efficiently when taken in smaller, divided doses. For the greatest benefit, we suggest taking 2 capsules with breakfast and 2 capsules with dinner.
Calcium and magnesium naturally bind to certain prescription drugs—including thyroid medications (levothyroxine), osteoporosis drugs (bisphosphonates), and specific antibiotics (such as ciprofloxacin or doxycycline)—which can reduce how well those medicines work. You should take this supplement at least 2 to 4 hours before or after any prescription medication, and always check with your doctor or pharmacist first.
Review of Calcium and Magnesium - Solaray Product 4531
Reviewed by Marie
Monday, May 9, 2011
This is the best calcium and magnesium supplement I've taken so far. It has zinc in it, which is important for calcium absorption. I would highly recommend it, so great for osteoporosis prevention since it is both calcium and magnesium. Definitely buy a jar or two, you won't regret it!
Marie ,
