UPC: 753950000698
# DRB-00069

High Absorption CoQ10 contains pure, vegetarian 
source Coenzyme Q10 in a base of rice powder, plus Bioperine®,
an herbal extract that enhances CoQ10
absorption. Benefits Boosts Cellular Energy
Production* Coenzyme Q10 is a vitamin-like nutrient found in
the human body. Essential to life, CoQ10 works at the cellular
level to produce metabolic energy in the form of ATP.*1,2 CoQ10
serves as a vital link in the “electron transport chain,” which
is the final step in the production of ATP inside cells. Lacking
adequate CoQ10, cells become energy-deficient. When cells are
nourished with optimal levels of CoQ10, tissues, organs and
systems function optimally. Strengthens and Protects the
Heart* The heart is the hardest-working muscle in the body.
Because of its high energy requirements, the heart needs to be
well supplied with CoQ10 at all times. The body’s highest
concentration of CoQ10 occurs in heart muscle tissue. (Heart
muscle cells contain large numbers of mitochondria.) Numerous
clinical studies have demonstrated significant improvements in
heart function with oral administration of
CoQ10.3,4,5 Supports Immune Function* When the immune system
goes into battle for us, immune cells need large amounts of
energy to carry out their defensive functions. CoQ10 is required
for this energy to be available. Experimental research on
animals has shown that CoQ10 enhances immune functions such as
the activity of phagocytes, and antibody production.*
Age-related immune suppression has been observed in mice given
CoQ10.6 Antioxidant Protection CoQ10 is a versatile
antioxidant.* The reduced form of CoQ10, ubiquinol-10, has been
found to protect LDL against peroxidation by free radicals more
effectively than vitamin E.* CoQ10 stabilizes membranes,* thus
protecting them from free-radical damage.7,8,9 Benefits the
Gums* A number of studies have shown that CoQ10 supports repair
of gingival (gum) tissue. Gingival tissues in people with
periodontal disease have been found deficient in CoQ10. In
several double-blind clinical trials, oral administration of
CoQ10 has resulted in significant improvements.10,11 Many
Clinical Benefits Research studies and clinical reports suggest
CoQ10 has a broad range of applications stemming from its
ability to support the heart and cardiovascular system, the
immune system, cellular energy production, liver function,
nerves, and muscles.* CoQ10 — Vitamin E’s Partner In vitro
studies suggest CoQ10 in combination with vitamin E protects LDL
cholesterol from oxidation more effectively than vitamin E
alone. Protecting LDL from being oxidized by free radicals is
now thought to be important for cardiovascular
health.9,12 Bioperine® — A Bioavailability-Enhancing
Phytonutrient Bioperine® is a natural extract derived from
black pepper that enhances nutrient absorption.* Preliminary
trials on humans have shown significant increases in the
absorption of nutrients consumed along with Bioperine®. In a
recent study (publication pending), the administration of 5 mg
of Bioperine® together with 120 mg of CoQ10 per day resulted in
a 32% increase in CoQ10 absorption after 21 days.13 (This is
especially important for individuals who have impaired
absorption of fat-soluble nutrients such as CoQ10.) *This
statement has not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat,
cure or prevent any disease. Scientific References 1.
Folkers, K., Wolaniuk, A., Progress in biomedical and clinical
research on coenzyme Q10. Drugs Exptl. Clin. Res. 1984;
X(7):513-517. 2. Lenaz, G., et. al., “The essentially of
coenzyme Q for bioenergetics and clinical medicine.” Drugs
Exptl. Clin. Res. 1985; XI(8):547-556. 3. Morisco, C.,
Trimarco, B., Condorelli, M., “Effect of coenzyme Q10 therapy in
patients with congestive heart failure: a long-term multicenter
randomized study.” Clin. Investig. 1993; 71:S134-S136. 4.
Mortensen, S.A., Vadhanavikit, S., Muratsu, K., Folkers, K.,
“Coenzyme Q10: clinical benefits with biochemical correlates
suggesting a scientific breakthrough in the management of
chronic heart failure.” Int. J. Tiss Reac. 1990;
XII(3):155-62. 5. Poggesi, L., et. al., Effect of coenzyme
Q10 on left ventricular function in patients with dilative
cardiomyopathy. Current Therapeutic Research 1991;
49(5):878-886. 6. Folkers, K., Wolaniuk, A., “Research on
coenzyme Q10 in clinical medicine and in immunomodulation.”
Drugs Exptl. Clin. Res. 1985; XI(8):539-545. 7. Littarru,
G.P., et. al., “In vitro effect of different ubiquinones on the
scavenging of biologically generated O2.” Drugs Exptl. Clin.
Res. 1985; XI(8):529-532. 8. Littarru, G.P. Lippa, S.,
“Coenzyme Q and antioxidant activity: facts and perspectives.”
Drugs Exptl. Clin. Res. 1984; X(7):491-96. 9. Stocker, R.,
Bowry, V.W., Frei, B., “Ubiquinol-10 protects human low density
lipoprotein more efficiently against lipid peroxidation than
does alpha-tocopherol.” Proc. Natl. Acad. Sci. 1991;
88:1646-1650. 10. Hansen, I., Iwamoto, Y., Kishi, T.,
Folkers, K., “Bioenergetics in clinical medicine. IX. Gingival
and leucocyte deficiencies of coenzyme Q10 in patients with
periodontal disease.” Research Communications in Chemical
Pathology and Pharmacology 1976; 14:729-738. 11. Wilkinson,
E. Arnold, R., Folkers, K., “Treatment of Periodontal and Other
Soft Tissue Diseases of the Oral Cavity with Coenzyme Q” (in)
Biomedical and Clinical Aspects of Coenzyme Q 1977; 1:251-266.
K. Folkers and Y. Yamaura, eds., Elsevier Science Publishing
Co., N.Y. 12. Thomas, S., Neuzil, J., Stocker, R.,
“Cosupplementation with coenzyme Q prevents the prooxidant
effect of alpha-tocopherol and increases the resistance of LDL
to transition metal dependant oxidation initiation.”
Arteriosclerosis, Thrombosis and Vascular Biology 1996;
16(5):687-96. 13. Badmaev, V., Majeed, M., “Comparison of
Coenzyme Q10 (CoQ10) bioavailability when ingested alone and in
combination with Bioperine®.” Sabinsa Corporation Research
Report. 1996 (unpublished).

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