|
Search Term: " 5-LOX "
Boswellia Reduces 5-LOX Activity   
Date:
December 09, 2016 01:35 AM
Do you tend to suffer from allergic reactions and inflammatory diseases which come as a result of chemicals which are naturally secreted inside the nucleus of the body cells? Well, certain chemicals, such as 5-lipoxygenase is such a reagent inside the blood and it can lead to things such as inflammation in the leukotrienes and other cancer-promoting conditions of the human body. This can even lead to other kinds of discomforts such as joint pains and aches, lung infections and infections of the intestinal tract. As such, it is very important that its activity as well as the impact on the person is reduced. Luckily, there is a solution for that and this comes in the form of Boswellia. Acting to counteract the effects of 5-LOX, Boswellia otherwise known as Indian frankincense has got a powerful impact on the said chemical which is responsible for the allergic reactions and inflammation of the body cells in the first place. As a result, these reactions are reduced thus promoting a healthy state of being. It is said to be the best natural fighter against the killer cancer and since it comes in an easy to assimilate form, it can get into the body system quickly thus acting to fight reactions just in the nick of time. It is truly important to live a healthy life which is free from all kinds of infections and allergies which can develop into further complications for the person. When you have a powerful drug to help with fighting such reactions within your body, you will notice that your body becomes progressively powerful and thus makes you able to withstand certain elements whose imbalances in the body might lead to inflammation. With Boswellia, you are able to become stronger against diseases naturally and you will also observe a gradual progression to a healthier, happier, more wholesome individual.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3601) Does Curamin work? 
Date:
December 22, 2012 11:00 AM
The Big Question: Does Curamin work? Well, this herbal supplement is a quick, natural and safe pain reliever, which has been proven to work. Moreover, the composition does not have any side effects on the body. It enhances the defense mechanism of the body against any inflammation. Curcumin (Inflammation Management) The main ingredient of Curamin, Curcumin enhances the anti-inflammatory components of the body and works as the immune system's modulator. This implies that whenever you consume Curamin, it renders long term effects on the body, thereby controlling oxidative stress. Nattokinase (Circulation and Inflammation) Curamin contains an enzyme referred to as Nattokinase, which helps the circulation of the body and thus nutrients reach all corners of the body. Therefore, whatever part of the body might be affected, you can experience results after a few minutes of consumption. Similarly, waste products are also removed from one's body via excretory system much more efficiently. Nattokinase balances the fibrinogen level, meaning the muscles are repaired quickly when they are injured as a result of heavy muscular strain. Curamin has DLPA (Mood Enhancer) DLPA amino acids which hinders the breakdown of enkephalins. Enkephalins are often associated with moods. Therefore, you'll never have irritating feeling while undergoing stress and pain anymore. You can carry out your daily activities or even have happy moments with your family during the pain and inflammation. 5-LOX (Inflammation Trigger) Most inflammations are triggered by uncontrolled behavior of the inflammatory enzyme, known as 5-LOX. This formula helps turn off the 5-LOX enzyme. Boswellia (Anti-inflammatory Herb) Curamin contains Boswellia serreta extract, a beta-boswellic acid, which hinders this enzyme's activity. Inflammation can be triggered by several factors. To handle all these factors, Turmeric: Curcumin longa is included in the Curamin. Curcumin longa, extracted from turmeric, is a great antioxidant. Inflammation and pain are common in life and they usually draw you back from having a stress free life. This is where Curamin comes in handy by offering the much needed relief to get rid of pain from your daily life. Curamin Has a money back guarantee if it does not work by the end of the bottle send it back for a refund. We offer free shipping and a $5.00 coupon on each bottle of curamin purchased.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2771) Use Curamin For Painful inflammation and see how your life can change!
Date:
June 15, 2010 05:10 PM
Pain is a warning signal that something has gone wrong in the body or that something is damaged. Pain is so unpleasant that it motivates you to remove yourself from the cause of this damage as quickly and completely as possible. There are four ways to relieve occasional pain: 1. You can leave the pain alone, but flood the body with feel-good substances that push the pain signals out from your consciousness (drugs). 2. you can put the person asleep and do surgical procedures to cut nerves and stop the pain. 3. You can impact the nervous system the internal wiring that carry the pain signals to dull them so that the signal becomes less distinct and weaker. 4. You can target what is causing the pain in the first place (most recommended). Occasional pain can be perfectly normal for instance, starting a new exercise routine when you are a bit out of shape. When dealing with type of pain, helping the body to balance its inflammation response can have tremendous impact.
This is where curamin is the answer to pain problems. They all break down as follows: DLPA: DL-phenylalanine is an amino acid consisting of equal parts D-phenylalanine and L-Phenylalanine. D- inhibits the breakdown or compounds called enkephalins. Enkephalins are associated with positive mood and have been shown to relieve occasional muscle pain due to exercise or overuse. L- is converted into tyrosine, which in turn is used to produce brain chemicals norepinephrine and dopamine.
Boswellia: Clinically tested boswellia helps reduce the activity of the inflammatory enzyme, 5-LOX (lipoxygenase). A compound (beta boswellic acid) found in boswellia which interferes with its benefitical activity has been removed, greatly increasing the effectiveness of this extract. Nattokinase: the enzyme nattokinase helps promote blood flow, aiding the other ingredients in the formula to reach all areas of the body. So if you are suffering from chronic pain, give curamin a try and see how well you can feel. If you are concerned about its effectiveness, have no fear, VitaNet ®, LLC offers a 100% Money back guarantee if the product does not work for you.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2167) Turmeric Extract (Curcumin)
Date:
February 10, 2009 01:18 PM
Curcumin is a potent antioxidant and anti-inflammatory that has the potential to provide far-reaching health benefits. It has been shown to be helpful in rheumatoid arthritis, inflammatory bowel disease, pancreatitis, Alzheimer’s disease, heart disease, diabetic retinopathy, and cancer. All of these diseases share underlying inflammation that curcumin may help to diminish. If you have ever eaten curry or cooked with the spice turmeric, you’ve consumed curcumin. It is obtained from the roots of Curcuma longa and consists of several curcuminoids. Turmeric is biologically related to ginger. Curcumin works as an antioxidant, boosting levels of glutathione S-transferase, which is one of the body’s principal antioxidants. This antioxidant blocks the formation of prostaglandin E2, which is a compound that promotes inflammation within the body. Curcumin also inhibits two inflammation-promoting enzymes: COX-2 and 5-LOX. Additionally, curcumin is able to prevent mutations to DNA, which is an effect that helps to maintain younger, healthier cells. A study conducted at the University of Arizona Health Sciences Center in Tucson had researchers using a curcumin rich turmeric extract to treat rheumatoid arthritis in laboratory animals. The extract blocked joint inflammation as well as the breakdown of joint cartilage and bone. It did this by inhibiting the genes that are involved in inflammation. Curcumin also holds tremendous promise in preventing cancer, as well as an adjunct treatment. Studies on animals have found that curcumin can protect against colon, intestinal, oral, and skin cancers. Its benefits come from several mechanisms. First of all, it blocks the cell-growth cycle in cancer cells, which eventually leads to destruction. It also reduces free radicals and inflammation, both of which can lead to cancer-causing cell mutations. Many studies have found that curcumin can protect the liver against a variety of toxic compounds, which is important news for those people who are suffering from liver diseases like hepatitis or cirrhosis. In a recent study, researchers reported that curcumin increased the clearance of creatinine and urea, which are signs of improved kidney function. Additionally, curcumin reduced liver damage from toxic chemicals and excess iron. Another study found that curcumin has the ability to inhibit the activation and spread of the liver cells that play a role in the development of cirrhosis. Japanese doctors have recently used curcumin, drugs, or placebos to treat 89 patients that have ulcerative colitis. These doctors found that a combination of curcumin and conventional medications resulted in the greatest benefits over six months of treatment. Patients in this study took 1,000 mg of curcumin after breakfast and again after dinner. Inflammation is the underpinning of all chronic degenerative diseases, making curcumin likely to be beneficial for many different conditions. So far, research has identified curcumin’s benefits for diabetic retinopathy, lung disorders, and skin problems such as psoriasis. A dose of 3.6 g of curcumin reduced PGE2 levels by two-thirds in only one hour. After consuming curcumin daily for one month, PGE2 levels were 57 percent lower than before supplementation began. Turmeric has been used as a culinary spice for at least 2,000 years. It was listed in an Assyrian herbal in 600 BC, used by ancient Greeks, and widely recommended in Ayurvedic medicine. Native to India and other regions of South Asia, it may reduce the risk of Alzheimer’s disease and help maintain mental function. Curcumin is safe in amounts of 500 to 8,000 mg daily, with most supplements providing 500 mg of curcumin.
Turmeric has been proven safe in larger amounts, but is usually limited by taste as a spice. One should look for a standardized supplement that contains at least 90 percent curcumin. Standardized Turmeric can be found at your local or internet health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1964) Curcumin, Curcuminoids, and Curamin
Date:
April 30, 2008 10:40 AM
Curcumin, a potent antioxidant and anti-inflammatory, possesses many potentially far-reaching health benefits. After many studies preformed on humans, animals, and in-vitro, it has been found that curcumin may be helpful in rheumatoid arthritis, inflammatory bowel disease, pancreatitis, Alzheimer’s disease, heart disease, diabetic retinopathy, and cancer. All of these previously listed diseases share an underlying inflammation, which can be diminished by curcumin. If you have ever eaten curry or cooked with the spice turmeric, you’ve consumed curcumin. Curcumin, which consists of several curcuminoids, is the active constituent of turmeric, which is used in curry. Turmeric is biologically related to ginger. Curcumin works as an antioxidant by boosting levels of glutathione S-transferase, which is one of the body’s main antioxidants. It also blocks the formation of the prostaglandin E2, which is compound that promotes inflammation within the body. Curcumin also inhibits the activity of nuclear factor kappa beta, which is another substance that is involved in inflammation. Additionally, it reduces the activity of COX-2 and 5-LOX, which are two more inflammation-promoting enzymes. Lastly, curcumin prevents mutations that can result in DNA, which helps to maintain healthier, younger cells. Curcumin taken as a supplement can help with any conditions and diseases including rheumatoid arthritis, cancer, liver and kidney protection, ulcerative colitis, and other inflammatory diseases. A study using a curcumin-rich turmeric extract done at the University of Arizona Health Sciences Center in Tucson, treated rheumatoid arthritis in laboratory animals. The results showed that this extract blocked joint inflammation as well as the breakdown of joint cartilage and bone by inhibiting the genes that are involved in inflammation. Curcumin also holds a great amount of promise in preventing cancer and also as an adjunct treatment. Animal studies have shown that curcumin can protect against colon, intestinal, oral, and skin cancers as its benefits come from several mechanisms. First of all, it blocks the cell-growth cycle in cancer cells, which leads to cell destruction. Additionally, it reduces free radicals by its antioxidant properties, which can lead to cancer-causing cell mutations. Studies have also found that curcumin can protect the liver from a variety of toxic compounds. One recent study left researchers reporting that curcumin increased the clearance of creatinine and urea, which are signs of improved kidney function. It also reduced liver damage from toxic chemicals and excess iron. Japanese doctors have recently used curcumin to treat patients with ulcerative colitis. A combination of curcumin and conventional medications has led to the best benefits over six months of treatment. Since inflammation is the root of all chronic degenerative diseases, curcumin is likely to be beneficial for many different conditions. So far, research has identified curcumin’s benefits for diabetic retinopathy, lung disorders, and skin problems including psoriasis. Turmeric, which is the source of curcumin, has been used as a culinary spice for the past 2,000 years, was used by ancient Greeks, and is now a widely recommended Ayurvedic medicine. It is native to India and other regions of South Asia. By eating a lot of curry, which is rich in curcumin, you may reduce the risk of Alzheimer’s disease and help to maintain mental function. One study proved that people who often ate curry had half the risk of becoming mentally impaired. By eating curry on occasion, the risk of mental decline can be reduced by a little more than a third. Curcumin can be safely taken in amounts from 500 to 8,000 mg daily. Look for a standardized supplement containing at least 90 percent curcumin.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1777) Celadrin and MSM Fact Sheet 
Date:
December 07, 2005 01:24 PM
Celadrin and MSM Fact SheetNeil E. Levin, CCN, DANLA Certified Clinical Nutritionist, Diplomate in Advanced Nutritional Laboratory Assessment Revised 11/10/05LIKELY USERS: People lacking flexibility or mobility; People wanting temporary control of aches and pains; People wanting to reduce pro-inflammatory body chemicals. KEY INGREDIENT(S): Celadrin® powder 500 mg. Provides 350 mg. of actual EFAC (esterified fatty acid carbons). This is a proprietary blend of Esterified Fatty Acid Carbons of Myristate, Myristoleate, Laurate, Oleate, Palmitate and Palmitoleate in a base of tapioca and silica. MSM 100 mg. MAIN PRODUCT FEATURES: CELADRIN® is an all-natural proprietary matrix of esterified (cetylated) fatty acid carbons (EFAC) derived from tallow of USA-raised cattle. This product is developed through a proprietary process of esterifying oil & has been clinically tested. Celadrin promotes joint health by improving flexibility, pain management and mobility. The myristoleic acids and the cetylated forms may alter the 5-LOX enzyme and change the leukotriene production, inhibiting inflammatory compounds. Celadrin® may offer some noticeable benefits faster than other substances, like glucosamine and chondroitin. Though it is not a substitute for these important tissue-building nutrients. ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: MSM has synergistic abilities to reduce certain substances in the body which may affect the inflammatory process. Contains Cetyl Myristoleate (CM, CMO), but in a patented blend of other fatty acid carbons. This product (Celadrin ®) has its own clinical studies showing safety and efficacy. Also will be available in a softgel of the same potency (350 mg. of EFAC) as of December 2005 (product 3017, 90 softgels) SERVING SIZE & HOW TO TAKE IT: Three capsules a day, preferably with meals. POSSIBLE SYNERGISTS: Glucosamine, Chondroitin, MSM, Joint Support Products, Manganese, Vitamin C, other Antioxidants CAUTIONS: None. SPECIFIC: None GENERAL: Pregnant and lactating women, and people using prescription drugs, should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new dietary supplement, use common sense and cautiously increase to the full-recommended dose over time, looking for possible side effects. Repeat this process for each new supplement that you start to use.
REFERENCES: 1. J Rheumatol. 2002 Aug;29(8):1708-12. Cetylated Fatty Acids Improve Knee Function in Patients with Osteoarthritis. Hesslink R Jr, Armstrong D 3rd, Nagendran MV, Sreevatsan S, Barathur R.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=985) | ||||||||||||||||||||||||||||||||||||
Everyone experiences occasional pain at some time in their lives. We use the word pain in our jargon to describe something unpleasant and to indicate the necessity of toughening up such as “no pain no gain”. As common as the word pain may be, there are many misconceptions about pain. Four out of five Americans believe that occasional pain is just natural and unavoidable due largely to getting older. More than one quarter of Americans believe there is absolutely nothing they can do to relieve their personal pain. 
Curamin contains four high potency ingredients that make it work so well. The first ingredient is curcumin from Turmeric. Curcumin is a super antioxidant with a ORAC value of 1592.27 each gram. That’s 24 times stronger than blueberries. Curamin also contains Boswellia, DLPA (DL-phenylalanine) which help fight inflammation and maximize the endorphins and enkiphalins in our own body. It finally contains nattokinase which is a systemic enzyme known to help improve circulation. 
Curcumin: Curcumin, a compound found in the spice of turmeric, inhibits multiple inflammation pathways in the body. It is also a potent antioxidant. Some of the benefits associated with curcumin include immune system modulation, protection from oxidative stress, and support the body’s natural anti-inflammatory response. The specialized extract in this formula has the highest absorption of any curcumin extract available for maximum health benefit. (Found in Curamin) 
