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Is AHCC Good for the Immune System? How So?
March 02, 2011 02:44 PM
AHCC And Immune Health
Active Hexose Correlated Compound, or AHCC, is one of the most commonly used food supplements in Japan largely owing to its effective immune-boosting properties when successfully absorbed by the human body. The earliest important study concerning its activities in the immune system was published in the early 1990’s at Tokyo University, triggering a sudden rise in popularity among consumers in Japan, where it is sold over the counter.
Activates White Blood Cells
It has been observed in the past few years that AHCC boosts the immune system in many different ways in that it participates not only in the innate immune system but also in the adaptive immune system. Of special note is the significant increase in certain types of white blood cells, including natural killer cells, or NK, and macrophages. NK cells are in the employ of the innate immune system and responsible for the disposal of cells infected by viruses. They are often the first line of defense against common viruses such as herpes, containing the damage that viral infection spreads while waiting for specified mechanisms of the adaptive immune system. This is when macrophages come into play along with a cohort of lymphocytes. Their relatively bigger size allows them to effectively engulf pathogenic cells and the enzymes they contain break these pathogens down.
Removes Antigens and Toxins
AHCC also influences the production of antigen presenting cells, or APC. In a double-blind, placebo controlled study involving healthy individuals there was a significant increase in the quantities of APC, notably dendritic cells, in comparison with the baseline, and proteins released by lymphocytes called interferon. Both APC and interferon facilitate the detection of antigens and toxins created by invasive foreign bodies and alert the rest of the immune system of their presence. Dendritic cells are considered the most important group of all APCs in that they present a wide range of antigen presentation by way of phagocytosis or endocytosis, two different ways of catching antigens. By so doing, they make it easier for white blood cells to eliminate antigens and other toxic substances.
Defends against Cancer Cells
Cancer patients are the group of individuals that have benefited the most from AHCC. Early studies yielded data that are now being used to enhance the quality of life of those diagnosed with cancer. Indeed boosting the immune system has proven to play a part in the battle against cancer, and AHCC stimulates the immune system to manufacture a class of white blood cells that actively defend the body against cancer cells by causing tumor cells to die and on the same principle delay the proliferation of malignant cells.
There have been extensive clinical trials well underway in many countries, including China, South Korea, Thailand, Spain, and the US. These studies aim to that rigorously test its efficacy. In fact, AHCC belongs to the group of nutritional products tied to alternative medicine that has been supported by an abundance of data in connection with its safety and recommended dosages.
If you are battling disease, give AHCC a try.
10 Top Winter Cold & Flu Supplements
January 14, 2008 10:01 AM
As the winter weather continues to keep people close together indoors, viruses causing influenza and the common cold are able to more easily multiply. However, there are ways to prevent these unwanted germs from invading your body. Here is a list of the top ten dietary supplements that help the immune system fight and repel cold and flu bugs.
Andrographis has long been used in Ayurvedic and Traditional Chinese Medicine to boost the immune system. Actually, andrographis was first used during the Indian flu epidemic of 1919, where it was credited with stalling the spread of the disease. According to research, andrographis works better than a placebo for reducing the symptoms of respiratory infections and it may even prevent the infection in the first place. These studies used a proprietary andrographis product which combines the herb with a Siberian ginseng.
Beta glucan is a fiber-like complex sugar that can be found in oats, barley, and the cell walls of mushrooms. It provides a boost to the immune system which enhancing resistance to viruses and bacteria. In fact, beta glucan has been shown to boost the activity of phagocytes, special immune system cells which engulf and destroy germs.
Echinacea has a long history of traditional use; with it actually being one of the most widely used herbs in Native American medicine. Instead of having a direct germ-killing effect, Echinacea stimulates the body’s own immune defenses. Many studies go back as far as 1970 have shown that Echinacea boosts the immune system so that it can protect against infections invaders. A new study has found that Echinacea can reduce the odds of developing a cold by 58 percent and shortens the length of a cold to 1.4 days.
Elderberry was considered in Roman times to be a flu remedy. Recently, elderberry extract has been researched for its role in treating influenza infections, especially when it is taken with in the first 24 hours of developing symptoms. One recent study proved that individuals who were taking elderberry recovered four days sooner from influenza than those taking a placebo. Additionally, the use of other medications was less for those who used elderberry.
Garlic improves resistance to disease by boosting immune function. Many studies have found that garlic stimulates immunity because it increases the number of white blood cells and other immune system team members. A recent study proved that a group of individuals taking garlic caught significantly fewer colds and recovered more quickly from the colds they did come down with than the other group which was taking a placebo.
Ginseng boosts immune function in all of its forms. A study of adults who were taking American ginseng daily during the winter months found that those people, compared to those taking a placebo, caught fewer colds and needed less sick days. Additionally, Siberian ginseng and Asian ginseng can also build defenses against winter germs.
Propolis is created by bees when resins from plants are mixed with wax. This propolis coats the inside of the beehive with an antiseptic layer and it can have similar benefits when taken by humans. Propolis stimulates the body’s immune system. It has been proven in studies that taking propolis extract can protect against colds and other upper respiratory infections. Children who take propolis daily for three winter months have been proven to catch fewer colds than those kids who are taking a placebo.
Zinc lozenges, when they are taken within 24 hours of the first cold symptom, can keep cold viruses from taking ground in the respiratory tract. The use of a zinc lozenge every couple of hours also causes colds to resolve more quickly and symptoms to be less severe.
Our immune system is out first line of defense against the cold and flu, as well as the diseases we may come down with. Keeping our immune system in tip top shape is key to a happier and healthier life. The above herbs can help boost the immune system along with a dietary change and exercise plan one can reduce the length of or prevent sickness over a life time.
ImmPower AHCC - Japan’s best selling immune enhancing supplement now available in the USA.
August 09, 2006 01:00 PM
In 1984, Japanese scientists discovered that by hybridizing several mushrooms used in traditional healing they could develop a natural compound that would give the body what it needs to maintain “super immunity.” Named active hexose correlated compound (AHCC), it has a unique alpha-1,4 glucan structure and low molecular weight that research shows provides unsurpassed support for the immune system’s front line defenses.
Based on over 20 published studies and the clinical experience of hundreds of hospitals and tens of thousands of consumers, AHCC has become Japan’s best selling immune enhancing supplement. Now its available in America as Immpower AHCC, where its gaining the endorsement of leading experts in nutritional medicine.
AHCC® Fact Sheet - from Now Foods.
December 08, 2005 10:20 AM
AHCC® Fact SheetNeil E. Levin, CCN, DANLA 6/30/05
LIKELY USERS: People needing increased activity of their Natural Killer cells; People seeking improved immune system response; People with a need for tissue repair; People with oxidative challenges; People seeking to increase liver function People defying aging or with a need to improve cellular integrity.
KEY INGREDIENTS: AHCC® (Active Hexose Correlated Compound)
MAIN PRODUCT FEATURES: AHCC® is a proprietary extract produced from specially cultivated and hybridized mushrooms. According to extensive research in humans, as well as numerous non-clinical studies, AHCC®supports immune system function through its effects on macrophages and NK (Natural Killer) Cells. NK cells and the intercellular mediators they produce are critical for the maintenance of healthy cell cycle function. AHCCR® has also been shown possess antioxidant properties, and supports healthy liver function.
ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: AHCC® (Active Hexose Correlated Compound) is a patented ingredient that has been the subject of research studies. It is supported by the scientific staff in the laboratories of both NOW Foods and the raw material supplier, both of which have a mutual interest in protecting the integrity and efficacy of this product.
AHCC® is a rich source of polysaccharides such as beta glucan 1,3 and activated hemicellulose produced by enzymatic modification of organic medicinal mushrooms, including shiitake. It also has been shown to support normal levels of macrophages and cytokines, further strengthening the immune system.
This formula is suitable for vegetarians and is offered in Vcaps.
SERVING SIZE & HOW TO TAKE IT: As a dietary supplement, take 2 Vcaps® 3 times daily, preferably on an empty stomach.
COMPLEMENTARY PRODUCTS: Antioxidants, Astragalus, Colostrum, Dr. Verghese Liver Formula, Immune Renew, Indole-3-Carbinol (I3C), Inositol Hexaphosphate (IP-6),
PRODUCT SPECIFIC: None
GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. When taking any new supplement, use common sense and cautiously increase to the full dose over time to avoid any potential problems. Packages may contain moisture or oxygen controlling packets or canisters that are not intended for consumption. In order to maintain maximum freshness, please do not remove these from your bottle (until the bottle is empty). Please recycle your container.
DISCLAIMER: Information given here may vary from what is shown on the product label because this represents my own professional knowledge and understanding of the science underlying the formula and ingredients. The information in this review should not be used as diagnosis, prescription or as a specific product claim.
Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Aviles H, Belay T, Fountain K, Vance M, Sun B, Sonnenfeld G. (2003) Active hexose correlated compound enhances resistance to Klebsiella pneumoniae infectin in mice in the hindlimb-unloading model of spaceflight conditions. J Appl Physiol 95:491-496.
Burikhanov RB, Wakame K, Igarashi Y, Wang S, Matsuzaki S (2000) Suppressive Effect of Active Hexose Correlated Compound (AHCC®) on Thymic Apoptosis Induced by Dexamethasone in the Rat. Endocrine Regulations 34:181-188. Matsui Y, et al. (2002) Improved prognosis of postoperative hepatocellular carcinoma patients when treated with functional foods: a prospective cohort study. J Hepatol. 2002 Jul;37(1):78-86. PMID: 12076865 Matsushita K, et al. (1998) Combination therapy of active hexose correlated compound plus UFT significantly reduces the metastasis of rat mammary adenocarcinoma. Anti-Cancer Drugs 9:343-350. Sun B, Wakame K, Mukoda T, Toyoshima A. Kanazawa T, Kosuna K (1997) Preventive Effects of AHCC® on Carbon Tetrachloride Induced Liver Injury in Mice. Nat Med 51(4):310-315.
Ye SF, Ichimura K, Wakame K, Ohe M. Suppressive effects of Active Hexose Correlated Compound on the increased activity of hepatic and renal ornithine decarboxylase induced by oxidative stress. Life Sci. 2003 Dec 19;74(5):593-602. PMID: 14623030 Ye SF, Wakame K, Ichura K, Matsuzaki S (2004) Amelioration by active hexose correlated compound of endocrine disturbances induced by oxidative stress in the rat. Endocr Regul 38(1):7-13.
Preventing Chronic Health Problems with AHCC
October 26, 2005 05:57 PM
Preventing Chronic Health Problems with AHCC
In a country supposedly as healthy as ours, an estimated 175 million people suffer from one form of chronic imbalance or another. This can take the form of obesity, which is the second leading cause of preventable death in the United States, second only to cigarette smoking; challenges to heart health, blood pressure, blood glucose levels, joint and cell health ,to name just a few.
In fact ,treating chronic health problems is what modern medicine has become .Sure, there are still many acute illnesses treated by modern medicine; but for the most part, we are fortunate enough to have long life spans and the health issues that go along with it. Therefore it is important to make sure that out immune systems are up to the task. That is where AHCC should become part of our daily lives.
AHCC is an nutritional supplement that was developed and is manufactured solely in Japan under strict practices. It is a hybridized extract of medicinal mushrooms where the active ingredient is an oligosaccharide made from the mycelia of several species of mushrooms, grown in rice bran.
AHCC and Cell Senescence
Every few years, a new buzz word comes along in medical circles. The latest one to be used both in a positive and negative fashion is senescence. For example, if an unhealthy cell can be artificially made to senesce, or grow old, then it will die sooner. If senescence of healthy cells can be delayed, that is an amazing achievement.
AHCC is the first nutritional supplement that shows principles of being able to promote certain cells in the immune system that keep us young and healthy, thus delaying immunosenesnscence.
AHCC and the Immune System
In order to get a full appreciation of how important taking AHCC on a daily bases is, one needs to understand the intimate role the immune system plays in our daily lives. It is responsible for riding our bodies of the unhealthy cells that are produced every day. The immune system protects us from the polluted air we breathe, the chemicaalized foods we eat, and most importantly, from the stress we bring upon ourselves just by the very nature of the way we live our lives. Our bodies were made for flight or fight capability; but never in history have we been in that mode on a daily basis. Our immune systems are under constant assault and it is up to you to take care of it even though you may not even be aware that it is there. We tend to only to think of our immune system when it is not working-when suffer mild or severe health challenges.
Without getting into too much detail, our immune system is a complex series of cells that all communicate with each other and must be balanced correctly in order for us to stay healthy. AHCC is able to encourage the helpful cells such as the natural killer (NK) cells while suppressing the ones that foster problems.
I am in clinical practice on a daily basis and use AHCC in almost every one of my patients. It is very versatile because of its effects on the immune system.
A Company Committed to Excellence
If everything I just told you wasn’t enough to convince you that AHCC should become part of your daily armamentarium, then here’s more fuel. AHCC is produced by a chemical company that is committed to excellence in manufacturing and most importantly in research. They have supported research at hospitals around the world, including local ones such as Columbia University, Harvard University and the University of California.
In fact, I just returned from a trip to Sapporo, Japan where the product is made and where each year, a team of scientists and medical professionals gather to discuss the latest research on AHCC, GCP, and oliganol-all products made by the same company. This was the 13th annual symposium and was attended by close to 1000 professionals.
It is remarkable to me that this company is able to produce such well-documented research while still being a nutritional supplement company, which shows it can be done. To me, this is the sign of a nutritional supplement worth recommending. If it does what it says it is supposed to do and has research to support those claims, than that is something you want in your daily diet.
So, even though you may never have given your immune system a second thought, you really should; and the best way to help it out is by taking AHCC on a daily basis, just like I do. I recommend 500 mg per day in the summer months and 1500 per day in the winter months as a simple preventive. Stay healthy!
About the Author
Fred Pescator, M.D., a traditionally trained physician practicing nutritional medicine, is President of the AHCC Research Association. He is the author of The Hamptons’ Diet, Thin For Good and Feed Your Kids Well. Dr.Pescator lectures around the world, and has been featured on such shows as The View, The Today Show, Deborah Norville, The O’ Reilly Factor, and Extra. Recent interviews include Woman’s Health and Fitness, Let’s Live, the New York Times, the Wall Street Journal, Fortune and more. He is also the author of numerous papers and magazine articals. Dr.Pescator is actively involved in clinical research , and is instrumental in developing and clinically testing many of the leading nutritional products. He is the President-Elect of the International and American Association of Clinical Nutritionists and a member of the National Association of Physician Broadcasters.
The above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider. The information in this article has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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October 26, 2005 05:18 PM
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June 18, 2005 09:11 AM
Mushroom Miracles by Bert Hoffman Energy Times, April 12, 2004
Mention mushrooms and few people immediately recognize these humble fungi as important tools that can be used to boost well-being. More often, folks identify mushrooms as food with a peculiar appeal. But mushrooms' potential impact on health far surpasses their culinary reputation.
You don't have to stretch your imagination too far to understand why mushrooms have been much neglected in the modern, Western medical search for plants that can boost health.
Unable to make chlorophyll, often dependent on the kindness of other nutrient-producing organisms for their survival, these humble fungal denizens of dark, damp spaces seem to prefer an anonymous existence that is out of sight and out of the consciousness of the scientific mind.
However, mushrooms have now assumed a spot in the center of the research spotlight. Because of their potent content of natural chemicals that appear to have a strong influence on human health and well-being, during the past decade mushrooms have been the subjects of intensive studies on how they can be used to reduce the risk of cancer and to treat these diseases.
Appropriately, this recent round of research began in a place that has long revered these diminutive organisms: Japan. Japan and other Oriental countries have traditionally recognized the immense value of mushrooms as both food and medicine.
Food and Medicine
As an ancient Chinese saying notes, "food and medicine share a common origin." And one of the very earliest Chinese medical books, Shen Noug's Herbal (Shen Noug Pen Ts'ao Jing), first noted the extraordinary beneficial effects of eating mushrooms 2,000 years ago, back in the first century.
More recently, but still well ahead of Western medical experts, in 1575, Pen Ts'ao Kang Mu (a Chinese compendium of medicinal therapies), written by Li Shi Zhen, outlined the medical benefits of about 20 mushrooms.
Nowadays, modern researchers believe mushrooms' usefulness stems from the fact they contain a wealth of antioxidants. But these aren't just any antioxidants. Scientists think that some of these chemicals can potentially drop your risk of cancer, significantly lower blood pressure, help the body fight diabetes, offer protection for the liver, alleviate some of the ill effects of inflammation, lessen the chance of blood clots and help the body's immune system fend off viruses and other microbes. Quite a collection of benefits for these lowly beings!
The 10,000-Year Mushroom
Through the ages, the reishi mushroom (also known variously as the Mannetake, or 10,000-year mushroom, and the Immortality Mushroom) has been the most popular mushroom in Chinese, Korean and Japanese cultures. The reishi mushroom is frequently depicted in a wide variety of traditional Oriental artwork and even puts in an appearance in Chinese royal tapestries.
To some, reishi's power goes beyond the natural and include the supernatural. Originally grown on aging plum trees, reishi is also sufficiently well regarded to be employed by the Japanese as a good luck charm. But you don't have to believe in the supernatural to be superbly impressed with reishi. The beneficial natural substances in reishi include steroids, lactones, alkaloids, triterpenes and polysaccharides.
Of these chemicals, polysaccharides (complex chains of sugars) in particular have intrigued researchers looking into the way mushrooms help health. These polysaccharide macromolecules are very large (for molecules) and complex, a complexity that leads researchers to believe they are capable of conveying a huge amount of biological information that help the immune system stop cancer in its early stages. The differences in the benefits of various polysaccharides stems from their intriguing geometrical shapes.
Even though two distinctive polysaccharides may contain the same number of carbon, hydrogen and oxygen atoms, their three-dimensional differences-the way they are structured and branch off in different directions-can endow them with very different health benefits.
Though they all share a basic structure (usually, these molecules consist of a main chain of atoms with various side chains), the slight variations of the side chains changes their effects.
By deciphering the microscopic structures of these molecules, scientists think they are beginning to uncover which ones are most effective against cancer. For instance, in isolating a particularly useful polysaccharide called beta-D-glucan from reishi, researchers have found that this substance fights tumors in lab experiments (Chem Pharm Bull 1981; 29: 3611).
Meanwhile, beta-D-glucan and other extracts taken from the maitake mushroom have also been shown to possess powerful anti-cancer effects in lab experiments (Immunopharm Immunotox; 19:175).
In one instance, researchers in the laboratory who were trying out various substances on prostate cancer cells found that applying extracts of maitake results in a kind of programmed self-destruction (apoptosis) of these undesirable cancer cells (Molec Urol; 4:7). In addition, another substance known as maitake d-fraction has been shown to strongly fight cancer in lab animals-in one study, their liver cancer growths were reduced by up to 90% (Ann NY Acad of Sci; 833:204).
At the same time, research in China on people has demonstrated that maitake may help reduce tumors and alleviate the effects of leukemia (Alter Comp Ther 12/98; 420).
According to A.S. Daba and O.U. Ezeronye (Afr Jrnl Bio 12/03; 672), "Mushroom polysaccharides offer a lot of hope for cancer patients and sufferers of many devastating diseases.
" [These substances support]...a fundamental principle in Oriental medicine...[they help] regulate homeostasis of the whole body and... bring the diseased person [back] to his or her normal state."
The Activity of Active Hexose Correlated Compound Active Hexose Correlated Compound (AHCC), an extract taken from shiitake and other mushrooms, is a relatively new substance that is also being researched for its anti-cancer benefits.
Studies on AHCC began in Japan in the 1990s when scientists looked at how it could potentially help people recovering from liver cancer. In those tests, researchers found that giving people AHCC apparently helped them survive longer.
In the future, scientists feel certain that they will uncover even more anticancer uses for mushrooms and the chemicals they contain. A key advantage to these natural substances is their lack of side effects. For instance, in research on an anti-cancer chemical called lentinan, taken from shiitakes, investigators have found that less than one percent of people experience the kind of discomfort that make them discontinue treatment. (This chemical has been used to treat stomach cancer.)
But a long list of beneficial mushroom substances are probably still waiting to be discovered. More evidence of mushrooms' benefits: A study of mushroom workers in a part of Japan called the Nagano Prefecture found that these farmers enjoyed a significantly lower cancer rate than other inhabitants of that part of the country.
In the rest of Japan, about one in six hundred people dies of cancer. But that rate death rate drops to about one in a thousand for mushroom raisers who eat a diet heavy in mushrooms.
John Smith, PhD, from the University of Strath-Clyde, notes that "...increasing evidence [shows] mushrooms offer a remarkable array of medicinally important compounds that have yet to be evaluated by Western medical scientists." Mushrooms offer the best of both worlds: good health that tastes great.
May 31, 2005 04:27 PM
The human immune system is the extraordinary biochemical network responsible for keeping us well. As our molecular interface with the environment, it has evolved complex interactions with the plant world. Mushrooms, which form one of the most primitive plant groups, have been valued for decades by progressive medical practitioners as immunopotentiators. Only recently, however, has science identified and tested the specific mushroom nutrients that augment natural defenses. AHCC® (active hexose correlated compound) is a proprietary mushroom compound. It is wellresearched in Japan for its immune-supportive properties, in particular the ability to increase natural killer cell and macrophage activity. Hundreds of Japanese hospitals and clinics recommend AHCC as part of an immune maintenance regimen, and its potent effects are so highly regarded that sales exceed $200 million dollars per year.
AHCC ®: A Unique Compound
AHCC, or “active hexose correlated compound,” is a rich source of polysaccharides (beta glucan 1,3 and activated hemicellulose) and glycoproteins, plus amino acids and minerals. It is produced by enzymatic modification of several types of medicinal mushrooms, including shiitake. AHCC is derived from organically cultivated mushroom mycelia (the rich pre-mushroom stage, a network of fibrous filaments plus the medium it lives on and uses for fuel). The low molecular weight of AHCC makes it easier to absorb.
Natural Killer Cell and Macrophage Activity
Your trillions of cells are susceptible to damage by free radicals and toxins, so a healthy immune system uses its first line of defense—natural killer (NK) cells—to quickly identify and destroy threatening particles. The effectiveness of NK cells depends on their activity level, so boosting NK activity is a smart strategy for those committed to maintaining vibrant health and longevity. AHCC is a potent biological response modifier that may significantly increase activity of NK cells and macrophages, according to human and animal studies. Literally “large things that devour,” macrophages are white blood cells that engulf and aid in the removal of foreign particles.
Studies show AHCC also enhances production of cytokines, including interferons and interleukins. These intercellular chemical messengers trigger white blood cell production and activity. In one recent study, AHCC was shown to support normal basal levels of two cytokines, as well as NK activity. It is rare for a natural compound to have such a profound impact on strengthening the immune system.
Your liver is your body’s chemical manufacturing and detoxification factory. It must handle the full brunt of assault from environmental contaminants and pharmaceuticals. Stress further burdens this overworked organ. Human studies suggest AHCC supports healthy liver function.
Your Source for Scientifically Advanced Nutrition
Source Naturals AHCC is the original proprietary compound that is attracting worldwide attention. And with no adverse side effects reported in dozens of studies and abstracts, it is certainly a nutritional approach worth considering. At a time when our systems are challenged by an unprecedented array of toxins, research into the remarkable immune-supportive properties of the plant world is critical. Source Naturals is your connection to this research, dedicated to quickly bringing you the benefts of the latest emerging wellness strategies.
References Uno, K. et al. Biother 2000 14(3) 303-309. Matsiu, Y. et al. J Hepatol 37 (2002) 78-86.
AHCC and its antifungal and antibacterial activity ...
May 25, 2005 11:19 AM
AHCC and its antifungal and antibacterial activity
The bacteria tested:
S. aureus, P. aeruginosa, P. fluorescens, Proteus vulgaris, Bacillus subtilis, B. cereus, B. megaterium, B. subtilis, Escherichia coli, Enterobacter aerogenes, Micrococcusluteus and Mycobacterium phei.
1.A ribonuclease with antimicrobial, antimitogenic and antiproliferative activities from the edible mushroom Pleurotus sajor-caju Patrick H.K. Ngai, T.B. Ng* Department of Biochemistry, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China Received 23 June 2003; accepted 25 November 2003
Immunomodulating and anti-tumor action of extracts of several mushrooms
May 18, 2005 10:11 AM
Quote from Abstract:
The outcomes obtained in the experiments in vitro have predetermined check of these extracts on antitumor effect in experiment in vivo.As a model of tumor growth, one of the most malignant tumors melanoma B16 was selected.
AHCC with proper diet and nutrition could help reduce tumor size and/or reverse cancer in humans as shown in lab animal examples.
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