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ACTIVATED QUERCETIN: a truly hypoallergenic formula...
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Date: May 31, 2005 04:45 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: ACTIVATED QUERCETIN: a truly hypoallergenic formula...

Most of us like to stroll through the countryside. Or play with our pets. Or eat our favorite foods. Or just stop and smell the beautiful flowers. But when our bodily systems are at odds with the natural world, these simple pleasures can be difficult to enjoy. That’s why the nutrition experts at Source Naturals created ACTIVATED QUERCETIN: a truly hypoallergenic formula developed so we all can enjoy the pleasures of nature.

Quercetin: A Unique Bioflavonoid Quercetin is a unique bioflavonoid that has been extensively studied by researchers over the past 30 years. Bioflavonoids - first discovered by Nobel Prize Laureate Albert Szent-Györgyi in the 1930’s - occur as pigments in plants, where they usually are found in close association with vitamin C. Together, bioflavonoids and vitamin C provide antioxidant protection, helping plants withstand harsh variations in wind, rainfall, temperature, and sunlight. Bioflavonoids also can be important to our optimal health - but they cannot be manufactured by our bodies.

Quercetin is no stranger to the human diet: for example, onions may contain up to 6% quercetin (dry weight). As a food supplement, quercetin is hypoallergenic, containing no citrus, wheat, corn, or other common allergens.

Histamine and Leukotriene Inhibition: Helping Us Enjoy the Natural World

Quercetin has a strong affinity for mast cells, the body’s main storage unit for histamines. Like many other bioflavonoids, it has the ability to stabilize cell membranes, preventing histamines from spilling out of mast cells into the bloodstream and surrounding tissues. Also, quercetin helps inhibit the action of two enzymes - phospholipase A2 and lipoxygenase - which act on arachidonic acid (a key fatty acid constituent of many cell membranes) to create leukotrienes. By inhibiting the release of histamines and leukotrienes into our bloodstreams, quercetin can leave us free to enjoy the natural world.

Activated for Absorption

Quercetin’s main disadvantage is that it is barely soluble in water, and therefore difficult for the body to absorb. Without biochemical help, its beneficial properties may be of very limited use to our bodies. There are lots of quercetin products on the market, but they won’t do much good if the quercetin is not activated for use by the body. Source Naturals combines its quercetin with bromelain, an enzyme derived from pineapple that is known to increase the body’s ability to absorb various substances. Bromelain also is known to have many of the same histamineand leukotriene-inhibiting properties as quercetin, so they enhance each others’ performance. Source Naturals ACTIVATED QUERCETIN contains vitamin C in a non-acidic form, magnesium ascorbate. Studies suggest that vitamin C has a synergistic relationship with quercetin, which improves quercetin’s use by the body. Since the acidic form of vitamin C (ascorbic acid) can create mild stomach irritation, and since quercetin is best taken on an empty stomach to maximize absorption, a pH-Buffered form of vitamin C such as magnesium ascorbate is preferable.

Combined Excellence

Source Naturals ACTIVATED QUERCETIN is a state-of-the-art quercetin complex. With 333 mg of quercetin in each tablet, and key additional ingredients to maximize quercetin’s absorption and beneficial properties, ACTIVATED QUERCETIN is a potent formula. It gives you more help - so you can enjoy nature again. Source Naturals ACTIVATED QUERCETIN is available in 50, 100 and 200-tablet bottles.

References

• Busse, W.W., Kopp, D.E., and Middleton, E. (1984). “Flavonoid modulation of human neutrophil function.” Journal of Allergy and Clinical Immunology, 73: 801-809. • Middleton, E. (1981). “Quercetin: an inhibitor of antigen-induced human basophil histamine release.” Journal of Immunology, 127: 546-550. • Pearce, F., Befus, A.D., and Bienenstock, J. (1984). “Mucosal mast cells: III. Effect of Quercetin and other flavonoids on antigen-induced histamine secretion from rat intestinal mast cells.” Journal of Allergy and Clinical Immunology, 73: 819-823. • Tarayre, J.P. and Lauressergues, H., (1977). “Advantages of combination of proteolytic enzymes, flavonoids, and ascorbic acid in comparison with non-steroid anti-inflammatory drugs.” Arzneimforsch. 27: 1144-1149.



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Search Term: " Buffered "

  Messages 1-6 from 6 matching the search criteria.
Vitamin C FAQ's Darrell Miller 12/27/05
Effer-C NUTRITION YOU CAN DRINK Darrell Miller 12/27/05
SalivaSure - from Scandinavian Formulas Darrell Miller 9/8/05
Source Naturals - Continuous Quality Assurance Darrell Miller 8/20/05
Bromelain Sinus Ease - Nature's Life Darrell Miller 6/16/05
ACTIVATED QUERCETIN: a truly hypoallergenic formula... Darrell Miller 5/31/05



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Vitamin C FAQ's
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Date: December 27, 2005 05:11 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamin C FAQ's

Vitamin C FAQ's

What is Calcium Ascorbate?

Calcium Ascorbate is a Buffered salt (mineral) form of the water-soluble antioxidant Vitamin C (ascorbic acid). Calcium is reacted with ascorbic acid to buffer the acidic nature of this vitamin, making it more gentle for the special needs of those who may have a sensitive gastrointestinal tract. The pH of this Buffered mineral Ascorbate is approximately 6.8—7.4 as compared to ascorbic acid that is about a pH of 2.5. Calcium Ascorbate provides approximately 10% elemental calcium.

What does Calcium Ascorbate do?

Ascorbate (vitamin C) is a reducing sugar (has a reactive ene-diol structure) that is involved in biochemical processes such as hydroxylation of proline and lysine utilized in the formation of collagen and healthy connective tissue. A deficiency in Ascorbate results in a disease called scurvy which manifests as weakened collagen fibers, rotting teeth, delayed healing and open sores on the skin. Ascorbate is involved in many other vital functions such as the mobilization of iron, stimulation of immune system and as an anti-oxidant for scavenging of reactive free radicals.

Is this a necessary vitamin or can our bodies make enough to satisfy our needs?

Many plants and animals do not need to consume foods high in ascorbic acid to meet their need for Vitamin C because they are genetically programmed to produce enzymes that convert glucose into ascorbic acid. Unfortunately humans have only 3 of the 4 enzymes necessary for internal production of ascorbic acid, therefore we must satisfy our physical needs for this important vitamin through our intake of foods rich in vitamin C and/or take a good supplement.

What is the function of the Citrus Bioflavonoids?

Bioflavonoids are biologically active Flavonoid compounds found throughout the entire plant kingdom. Since the discovery of Flavonoids in 1936 when they were first isolated from lemons and called citrin and Vitamin P over 4,000 different types have been characterized. Though there are several forms of Bioflavonoids in the complex the predominant form is Hesperidin. These Flavonoids exhibit beneficial effects on capillary permeability and therefore support blood flow. They are antioxidants that work synergistically with Vitamin C as well as exhibiting anti-inflammatory activity.

Why are there color variations in your different Vitamin C products, and are they safe to take?

Most natural Vitamin C products vary in color from batch to batch and bottle to bottle. There are normally variations in the color of the raw material used during manufacturing, which is a normal occurrence. This is due to natural color variations in the source of the Vitamin C – generally, you will find C supplements to range in color from a light tan color to a light gray color.

Over the course of the shelf-life of a Vitamin C supplement, oxidation can cause a slight change in color, so you may find the light tan C-1000 you bought has changed to a darker tan six months later. This is a normal occurrence, and the product is safe to use up until the expiration date, and even beyond. NOW® is generally conservative with expiration dates, so a Vitamin C product is still safe after the date, it just may not be as effective due to oxidation.

Why does your Ester-C Complex say 625mg on the front of the label but list 500mg on the Supplement Facts panel? The key word is “complex”. Ester-C Complex is a combination of ascorbic acid (natural Vitamin C) and Calcium Ascorbate, which ultimately yields 500 total mg of Vitamin C. It is complexed with Calcium Ascorbate and other metabolites for greater absorption and faster utilization by your body. So the total complex is 625mg of Ester-C Complex, which yields 500mg of natural Vitamin C as ascorbic acid.

NOW Ester-C Pure Powder states the serving size is ½ teaspoon. How much Vitamin C am I getting with this serving size? ½ teaspoon of Ester-C Pure Powder is equivalent to 2000mg of natural Vitamin C and 250mg of Calcium.

Can I pour the powder in NOW® Vitamin C capsules into a liquid instead of swallowing the capsule? Many people do not want to or cannot swallow capsules, tablets or softgels, for various reasons. Encapsulated Vitamin C products from NOW® can be opened and dumped into a liquid for consumption. Juice or water is recommended if you choose this method. However, taking Vitamin C with water on an empty stomach is the recommended method of ingestion. We do not recommend trying this method with Vitamin C in tablet form, although you can grind or smash a tablet into powder form and add to water or juice. If you choose to do this, use a mortar and pestle for best results and minimal loss of product. Why go through the trouble when NOW® carries Vitamin C in a powdered form already. Save yourself time and trouble by ordering this form instead. Disclaimer: This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

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Effer-C NUTRITION YOU CAN DRINK
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Date: December 27, 2005 09:49 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Effer-C NUTRITION YOU CAN DRINK

Effer-C NUTRITION YOU CAN DRINK

  • 1000 mg of Vitamin C Per Serving
  • Helps Restore Vital Electrolytes
  • Includes CoQ10 and Alpha Lipoic Acid
  • High in Energy-Producing B Vitamins
  • 4 Great Tasting Flavors

Vitamin C (ascorbic acid) is unquestionably one of life’s most important nutrients. Everyday we unknowing rely on it to help protect cells, produce energy, repair tissue and replenish lost electrolytes. Ironically, humans are just one of a handful of living creatures unable to produce our own supply of this vital nutrient. In fact, your dog can naturally manufacture upwards of ten times the amount of vitamin C that you might obtain in an entire day from food.

To make matters worse, vitamin C can be a terribly stubborn nutrient. Not only are we incapable of producing it, but getting adequate amounts from the diet is a task all in itself. Today’s typical diet has become just that, typical. The convenience of fast food, sodium-rich snacks and over-processed heart bombs has reduced our once healthy society to a scrambling cluster of time-pressed professionals who’ve somehow forgotten what it’s like to actually prepare balanced, nutritious meals. This makes obtaining the nutrients we so desperately need, next to impossible.

As if that wasn’t enough, vitamin C has a short halflife. Half lives measure the amount of time that it takes for one-half of a nutrient to be depleted from the bloodstream. In the case of vitamin C, it has a half life of just 30 minutes. For the sake of argument, let’s assume that your 7:00 AM breakfast includes an orange that contains a modest 70 mg of vitamin C. By 8:00, you’re left with only 35 mg. By 9:00, a mere 17 mg. And by the time lunch rolls around, you’ll be lucky to have any vitamin C in your system at all. This should be of great concern to anyone who doesn’t carry a bushel of oranges around at all times. Because aside from the fact that the body rapidly depletes its reserve of vitamin C, it also depends on what remains to carry out an long list of biological tasks. When it’s not there, everything suffers - energy, metabolism, immune response, cartilage integrity and so on.

So how does one contend with this taxing concoction of unceasing stress, high-throttle lifestyle, endless toxins and pathetic dietary habits? It’s actually much simpler than you might imagine. Thanks to new technology in the nutritional sciences, getting the C you need no longer requires carrying around bottles of capsules or huge sacks of fruit. Effer-C™ from NOW® is an effervescent vitamin C unlike any other, and was designed to quickly replenish the vital electrolytes needed to keep you running strong. With a nutritional profile superior to other fizzy C drinks, a taste that won hands-down in blind tests and an exceptional grade of ascorbic acid, Effer-C™ is clearly the smart choice.

Vitamin C

Starting with a exceptional grade of Vitamin C was the first step in formulating this superior drink. Fueled by 1000 mg of highly absorbable, gentle vitamin C, you can be assured that you’re getting enough C to keep you tip-top for hours. By utilizing a Buffered, non-acidic vitamin C, Effer-C™ offers fast assimilation to boost energy and restore vital electrolytes without causing gastric irritation.

B-Complex

Busy lifestyles rob you of so much more than just time. Physical stress and mental anxiety can drain even the healthiest individuals of energy producing, mood supporting B vitamins. As these reserves diminish, so does the ability to stay motivated, focused, patient, responsive and energetic. Effer-C™ is bursting with a full B profile that contains as much as two times the amount of certain B-vitamins found in other brands.

Calcium/Magnesium

Calcium and magnesium have become synonymous with strong, healthy bones. Aside from their structural supporting properties, these two minerals work synergistically to help support the body’s adenosine triphosphate (ATP) energy reserves. Individually, magnesium is present in virtually every human biological process. Many of today’s most common elements (alcohol, fluoride, processed foods) can hinder your ability to retain optimal levels of this vital nutrient. Effer-C™ brings them right back!

Chromium

This essential trace mineral is a primary component in the synthesis of fats, carbohydrates and proteins. Chromium also has a direct influence on the efficacy of our metabolism, in addition to how well we use glucose. Even a slight deficiency in chromium can result in fatigue, anxiety and glucose intolerance. Effer-C™ contains 20 mcg of chromium - more than even the most popular effervescent C supplement.

Anti-oxidants

Part of what makes Effer-C™ so effective is its unique antioxidant profile. By adding more alpha lipoic acid (ALA) than similar competing products, in addition to 5 mg of CoQ10 and zinc, Effer-C™ provides powerful protection against harmful, cell damaging free radicals. If you haven’t experienced the nutritional rush that Effer-C™ delivers, you don’t know what you’re missing. NOW makes it easier than ever to stay energized and fully replenished throughout the day, during workouts and even on the road. Available in four delicious flavors (orange, lemonlime, raspberry and cranberry Effer-C™ is a simple and effective way to maintain high levels of vitamin C and unlock the energy that’s just waiting within.

EFFER-C RASPBERRY from NOW EFFER-C LEMON LIME from NOW EFFER-C CRANBERRY from NOW EFFER-C ORANGE from NOW



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SalivaSure - from Scandinavian Formulas
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Date: September 08, 2005 10:04 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: SalivaSure - from Scandinavian Formulas

SalivaSure

SalivaSure - Is a fast relief from dry mouth for those on medication, with diabetes or with immune deficiencies. Buffered to protect the teeth and to help prevent tooth decay. Patients appreciate its convenience and pleasant taste and will carry SalivaSure wherever they go.

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Source Naturals - Continuous Quality Assurance
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Date: August 20, 2005 11:44 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Source Naturals - Continuous Quality Assurance

“I oversee all the inspections, tests, and document reviews performed by our dedicated Quality Control staff to ensure that nothing compromises the healthfulness and high quality of our products.” Norm Nelson, Ph.D., Quality Control Director

Continuous Quality Assurance

Our Quality Control Department includes staff trained in microbiological assays, heavy metal screening, analytical chemistry and Eastern and Western herbalism. They utilize procedures that go beyond minimum industry requirements to ensure product excellence. All raw materials and finished goods must meet our inspectors’ rigorous quality specifications at every stage of manufacturing.

Pure Raw Materials

Bulk raw materials must be accompanied by Certificates of Analysis provided by the vendors. They are sampled and inspected according to a long list of specifications, including appearance, color, odor, flavor, texture, absence of extraneous material, and potency of active constituents. Vitamins, minerals and amino acids are screened and/or tested for impurities, while materials, such as herbs, that are biological in origin are tested for microbiological contamination.

Bioavailable Manufactured Product Inspectors scrutinize finished tablets to see that they meet our standards for consistency in size, color, aroma or taste, are not broken, and contain no contaminants. Representative samples are taken to verify potency. Tablets and capsules are tested to ensure they are consistent in size and comply with USP standards for weight variation. Threshold utilizes USP disintegration standards* as its guidelines to ensure tablets will break up appropriately after ingestion, making the ingredients available for use by your body.

*Under USP 25 standard conditions: Coated tablets: 50 minutes in water. Capsules: 45 minutes in Buffered acetate or water.

Rigorous Laboratory Procedures

Methods used include: HPLC (High Performance Liquid Chromatography), IR (Fourier Transform Infrared), UV/Vis Spectrophotometry, Graphite Furnace Atomic Absorbance Spectroscopy, TLC (Thin Layer Chromatography), Microbiology testing, and organoleptic inspection including visual, color, odor, clarity, pH, and taste.

Raw materials must comply with vendor Certificates of Analysis as well as with our rigorous specifications.

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Bromelain Sinus Ease - Nature's Life
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Date: June 16, 2005 10:57 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Bromelain Sinus Ease - Nature's Life

Bromelain Sinus Ease™


 

Nature's Life Sinus Products:


 

Sinus cavities are lined with delicate mucous membranes, which act as filters for your respiratory system. Normal sinuse tissues are pink and healthy. For many people, when their sinuses come in contact with allergens, pollutants or harmful micro-organisms, histamines are released as a protective measure by the immune system. Sinuses naturally respond by becoming irritated, red, and inflamed with these healing histamines. This process, called the natural inflammatory response, helps to neutralize and remove the irritants in sinuses cavities. Sometimes, however, the immune system continues to flood the sinuses even after the irritants are removed. Bromelain Sinus Ease™ contains three ingredients that have been shown to enhance the body’s ability to reduce this natural inflammatory response and help clear up sinuses.*

Bromelain

Bromelain is a group of protein-digesting enzymes extracted from pineapples (Ananassa sativa). Bromelain breaks down fibrin—a key component of the body’s natural inflammatory response to allergens and other foreign stimuli.* Bromelain also appears to inhibit the natural formation of prostaglandins (hormone-like substances) that trigger the natural inflammatory response.*1  It makes mucus less thick,2  allowing the mucus to drain more easily.*

Human trials have shown that by breaking down and helping to remove fibrin, bromelain reduces the discomfort of irritated tissues.*3   Double-blinded trials in patients with irritated sinuses show that the natural inflammatory response is reduced more effectively by concentrated bromelain than by placebo.*4 ,5 ,6 ,7  In all cases, a majority of people responded well to bromelain supplements.*

Bromelain has also helped reduce the dura­tion of the natural inflammatory response after nasal procedures by over 70% in a controlled trial.*8 

The recommended daily amount of Nature’s Life Sinus Ease™  utilizes 1,200 mg a very high potency bromelain enzyme which has an activity of 2,880 GDU (Gelatin Digestive Units), or 4,320 MCU (Milk Clotting Units) per serving.

Vitamin C

Vitamin C also helps reduce histamine release.*9   Some studies have reported that vitamin C is useful in reducing the natural inflammatory response in nasal passages.*10, 11, 12   The effectiveness of vitamin C in reducing histamine release is still debated, however, because a controlled trial was unable to show consistent effects.*13  Doses up to 2 grams per day have been used by researchers. It may be diffi­cult to show these effects in research trials because vitamin C appears to help only some people without affecting others.*14  Studies, however, clearly show that vitamin C supplementation can lower elevated blood levels of histamines.*15, 16 Nature’s Life adds naturally-Buffered vitamin C to Sinus Ease due to its safety, immune-supporting effects and potential effica­cy to reduce histamine release.*

Quercetin is a bioflavonoid found in many natural foods including citrus fruits, onions, apples, tea and lettuce. As with bromelain, quercetin helps reduce the natural inflammatory response by inhibiting the natural formation of the pro-inflammatory agents, prostaglandins and leukotrienes (white blood cells).*17,18  Quercetin also helps lessen the natural inflammatory response for children with sensitivities to inhalants.*19  Additionally, quercetin may help reduce the effects of harmful micro-organisms *20  Bioflavonoids at doses of 1,200 mg per day have reduced the natural inflammatory response in human studies in combination with 1,200 mg vitamin C,21 an outcome con­firmed in double-blinded research using 600 mg/day of bioflavonoids and 450 mg/day of vitamin C.*22

Substances which inhibit the natural inflammatory response rarely target just one part of the body.* While quercetin has yet to be tested in reducing the natural inflammatory response in sinuses specifically, doctors of natural medicine frequently use it for that purpose because of its proven ability to lessen the natural inflammatory response elsewhere in the body.*

Nature’s Life Sinus Ease™

Nature’s Life has combined these powerful phytonutrients to make Sinus Ease™. High potency Bromelain, Quercetin and vitamin C work to inhibit the natural pro-inflammatory response and encourage adequate sinus drainage.* No safety concerns have been identified with any of these ingredients.23, 24  It is recommended to take the three capsules per day between meals. Since bromelain is a proteolytic enzyme, if taken with a meal it will act on the protein in the food rather than the natural pro-inflammatory fibrin, so remember to take it between meals.*  Enjoy the winter season and find relief from allergens throughout the year!  Nature’s Life Sinus Ease™ can help.

References:

  1.   Taussig SJ. The mechanism of the physiological action of bromelain. Med Hypoth 1980;6:99-104.

  2. Martin GJ. Bromelain pineapple proteases with anti-edema activity. Exper Med Surg 1962;20:228-48.

  3. Blonstein JL. Control of swelling in boxing injuries. Prac­titioner 1969;203:206.

  4. Seltzer AP. Adjunctive use of bromelains in sinusitis: a controlled study. EENT Monthly 1967;46:1281-8.

  5. Taub SJ. The use of Ananase in sinusitis—a study of 60 patients. EENT Monthly 1966;45:96-8.

  6. Ryan RE. A double-blind clinical evaluation of bromelains in the treatment of acute sinusitis. Headache 1967;7:13-7.

  7. Taub SJ. The use of bromelains in sinusitis: a double-blind clinical evaluation. EENT Monthly 1967;46:361-5.

  8. Seltzer AP. Minimizing post-operative edema and ecchymoses by the use of an oral enzyme preparation (bromelain). EENT Monthly 1962;41:813-7.

  9. Johnson CS, Martin LJ, Cai X. Antihistamine effect of sup­plemental ascorbic acid and neutrophil chemotaxis. J Am Coll Nutr 1992;11:172-6.

  10. Zuskin E, Lewis AJ, Bouhuys A. Inhibition of histamine-induced airways constriction by ascorbic acid. J Allergy Clin Immunol 1973;51:218.

  11. Ruskin SL. High dose vitamin C in allergy. Am J Dig Dis 1945;12:281.

  12. Holmes HN. Hay fever and vitamin C. Science 1942;96;497.

  13. Fortner BR, Danziger RE, Rabinowitz PS, Nelson HS. The effect of ascorbic acid on cutaneous and nasal response to histamine  and allergen. J Allergy Clin Immunol 1982;69:484-8.

  14. Bai TR, Martin JG. Effects of indomethacin and ascorbic acid on histamine induced bronchoconstriction in normal  subjects. NZ  Med J 1986;99:163 [abstr].

  15. Holmes H, Alexander W. Hay Fever and Vitamin C. Science 1942;96:497-99.

  16. Johnston CS, Martin LJ, Xi C. Antihistamine Effect of Supplemental Ascorbic Acid and Neutrophil Chemotaxis. J Am Coll Nutr 1992;11:172-6.

  17. Middleton E, Drzewieki G. Naturally occurring flavonoids and human basophil histamine release. Arch Allergy Applied Immunol 1985;77:155-7.

  18. Welton AF, Tobias LD, Fiedler-Nagy C, et al. Effect of flavonoids on arachidonic acid metabolism. Prog Clin BiolRes 1986;213:231-42

  19. Balabokin II, Gordeeva GF, Fuseva ED, et al. Use of vitamins in allergic illnesses in children. Vopr Med Khim (Russia) 1992;38:36-40.

  20. Ohnishi E, Bannai H. Quercetin potentiates TNF-induced antiviral activity. Antiviral Res 1993;22:327-31.

  21. Miller MJ. Injuries to athletes. Med Times 1960;88:313-6.

  22. Cragin RB. The use of bioflavonoids in the prevention and treatment of athletic injuries. Med Times 1962;529-32.

  23. Taussig SJ, Yokoyama MM, Chinen N, et al. Bromelain: A proteolytic enzyme and its clinical application. Hiroshima J Med Sci 1975;24:185-193.

  24. Hertog MGL, Feskens EJM, Holman PCH, et al. Dietary flavonoids and cancer risk in the Zutphen elderly study. Nutr Cancer 1994;22:175-84.

 



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