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Search Term: " Leucine "
six top-notch supplements that can help you achieve your goals.   
Date:
December 06, 2023 04:55 PM
If you're looking to stay in the game longer and improve endurance while promoting rapid recovery, we've got you covered! six top-notch supplements that can help you achieve your goals.For most of us, life can feel like quite the balancing act. In an ideal world, we would all have ample time throughout the day to dedicate to our health and well-being. However, reality paints a different picture, where 24 hours can seem like an insufficient amount of time to squeeze in work, school, family, and the countless responsibilities that life throws at us. In recent years, the use of supplements for recovery has gained popularity, becoming more common than ever before. Our bodies face a barrage of daily stresses, including exposure to environmental toxins, electromagnetic pollution, and the strain of intense physical activity. These factors increase our body's demands for antioxidants and essential nutrients that aid in the process of recovery. While consuming antioxidant-rich foods can certainly make a difference, it can be challenging to meet these requirements solely through our diet. That's where a well-rounded supplement regimen can play a crucial role in promoting optimal health and aiding in recovery. Even with our best efforts to exercise regularly, eat nutritious meals, and get sufficient sleep, life in the 21st century can be incredibly demanding, depleting our bodies on a cellular level. For athletes, consistent training is key to reaching desired performance levels. It's important to understand that the muscle recovery and building process primarily occurs between gym sessions. Developing a comprehensive recovery strategy during this crucial window, through the use of supplements, proper nutrition, and adequate rest, can help athletes perform at their best week in and week out. Failing to make the most of this recovery period may result in free radical damage and delayed onset muscle soreness (DOMS). To maximize the benefits, it's important to prioritize food as the primary source of vital nutrients, while also recognizing the significant role supplements can play in providing the necessary building blocks for muscle repair due to their rapid absorption rate. However, it's essential to ensure that any chosen supplements are clinically validated, demonstrating efficacy and supported by solid scientific evidence. In today's fast-paced world, there is a growing demand for quick and convenient solutions to jumpstart the recovery process. Nevertheless, when it comes to choosing supplements, it's important to remember that one size does not fit all. The market offers an overwhelming array of options, often leaving individuals feeling bewildered about which products to select. Before diving into my recommendations for the top six supplements to aid in recovery, I believe it's crucial to emphasize the significance of cellular renewal and its direct impact on the recovery process. This, in my opinion, serves as the key to achieving a quick and effective recovery. Oxidation and Free Radical DamageA fundamental key to staying young and maintaining optimal health is cellular renewal and minimizing the damage to cells over time. We all age, but studies have shown that some individuals age better than others. Have you ever wondered why? Well, recent research has linked oxidative stress to the aging process. So, what exactly is oxidative stress? Allow me to explain in simple terms – oxidation occurs when the body produces by-products commonly known as free radicals. It's almost like a machine rusting, but instead of rust forming on iron, our bodies experience the effects of aging and age-related diseases. Now, our bodies naturally produce free radicals as part of our daily metabolism, and they can also be produced as a result of environmental pollutants from everyday things like air, water, and even sun exposure. As we age, our bodies become more vulnerable to the long-term effects of oxidative stress, which simply means we accumulate too many free radicals and experience increased inflammation at the cellular level. As interesting as it may sound, the process of oxidation is actually abundant and can be beneficial for our bodies to function properly. But, and this is an important "but," this very process can also cause potential harm. You see, the oxidizing process creates these molecules called free radicals, which are electrically charged. These free radicals interact with our cells, and this interaction can lead to both positive and negative outcomes. For example, our immune system utilizes free radicals to help fight infection. However, when LDL cholesterol (often referred to as bad cholesterol) is oxidized, it can become a concern (cholesterol buildup). Let's talk about oxidative stress. It occurs when the level of free radicals overwhelms the body's natural antioxidant defense system, resulting in cell damage. As I mentioned earlier, while free radicals serve useful functions in the body, they are highly unstable molecules. If they remain uncontrolled, they have the potential to wreak havoc by causing damage to cells, enzymes, and even our DNA, which ultimately accelerates the aging process. In addition, these free radicals can also contribute to the development of various age-related diseases, including arthritis, cancer, and heart disease Now, inflammation is triggered by free radical damage, and it is this inflammation that leads to the negative effects of free radicals due to oxidation. The question then becomes, how can we address this in our daily nutritional regimen? The answer lies in the incorporation of antioxidants, which play a vital role in combating oxidative stress and minimizing the damage caused by free radicals in our bodies. You'll be glad to know that there are foods rich in antioxidant content that can help us on this journey. In fact, certain foods contain phytonutrients that, according to many health professionals, hold the potential to unlock the secrets of longevity and overall well-being. So, my dear friend, let's take a proactive approach, nourish our bodies with antioxidant-rich foods, and strive to minimize the effects of oxidative stress caused by free radicals. It's never too late to make positive choices for our health and age gracefully. Phytonutrients, also known as health boosters, are substances produced by plants to protect themselves from harmful bacteria and viruses. However, these compounds also offer significant benefits to the human body. Packed with essential nutrients, phytonutrients play an active role in promoting good health. They belong to the antioxidant family, responsible for eliminating harmful free radicals and thus slowing down the aging process. Incorporating a diet rich in high antioxidant foods like fresh fruits and vegetables is crucial as the first line of defense against aging. While vitamins A, C, and E are commonly known antioxidants, there are other antioxidants available in both food and supplement form. These antioxidant supplements play a vital role in bridging the nutritional gap left by processed foods, lacking the necessary antioxidants and nutrients to combat free radicals effectively. Let's take a closer look at my top six supplement recommendations, known for their efficacy in fighting oxidative stress and promoting optimal recovery: Beta Alanine: As an amino acid derivative, Beta Alanine is proven to enhance intramuscular carnosine content, improving the body's ability to buffer hydrogen ions. During exercise, the body accumulates hydrogen ions, contributing to fatigue and lowering pH levels. Beta Alanine supplementation can reduce fatigue, enhance exercise performance, and increase training volume. Whether it's interval training or weightlifting to improve running economy, incorporating beta-alanine can have a positive impact on endurance performance and overall training results. BCAAs: Branched Chain Amino Acids (BCAAs) have become a staple supplement for athletes due to their role in muscle and energy production during exercise. Consisting of three essential amino acids - Leucine, isoLeucine, and valine - BCAAs have been shown to significantly reduce muscle soreness and expedite the recovery process. Supplementing with BCAAs helps prevent muscle breakdown, as the body does not need to rely on its own muscle tissue for energy. Consequently, protein synthesis remains high, supporting muscle growth and repair. Creatine, a natural molecule found in muscle cells. When engaging in high-intensity workouts like weightlifting, Creatine helps your body produce adenosine triphosphate (ATP), a vital energy source. This amazing compound improves strength, boosts lean muscle mass, and aids in faster muscle recovery. Flavonoid Root, a breakthrough extract known for its cardiovascular benefits. This extract is packed with potent antioxidants and acts as a nitric oxide booster, promoting increased endurance during workouts. Studies have shown that it fights against free radical damage and increases the flow of oxygen-rich blood, ensuring optimal cardiovascular health. You can also boost nitric oxide with beet root, and l-citruline. Speaking of studies, a published research paper in Food and Nutrition Research (April 2016) highlighted the effects of the unique flavonoid root extract on arterial health. The study revealed that after one year of consumption, participants experienced a decrease in artery wall thickness, total cholesterol, LDL levels, and blood pressure. This indicates that the extract may help reduce the risk of oxidation-related cerebral vascular issues and improve overall cardiovascular health Glutamine. It's the most abundant amino acid in the human body and plays a vital role in muscle recovery and repair. Glutamine aids in preventing muscle soreness, optimizing post-workout recovery, and supporting muscle rebuilding. By facilitating nitrogen transport, regulating acid-base balance, and acting as an antioxidant, Glutamine ensures faster post-workout muscle recovery, giving you the freedom to train harder for better results. Protein plays a crucial role in replenishing and repairing your muscles after a workout, making it a key nutrient to consume alongside carbohydrates. By opting for a protein shake as a post-workout option, you can efficiently supply amino acids to your muscles, stimulating muscle protein synthesis, enhancing recovery, and promoting growth. It's important, though, to choose a protein shake that contains high-quality ingredients, as prioritizing quality over quantity is key when it comes to protein. Apart from protein, there are several other supplements that work through various mechanisms to provide natural, broad-spectrum antioxidant and nutrient support, ultimately contributing to optimal health and recovery. Taking preventative measures to protect the health of different body systems is much easier than trying to restore their function after damage has occurred. With this in mind, retailers should suggest a preventive program to their customers, aiming to limit free radical damage and promote recovery. As the adage goes, "an ounce of prevention is worth a pound of cure," emphasizing the significance of protecting and preserving one's health. In conclusion, the role of antioxidants, particularly phytonutrients, in maintaining overall health and combating oxidative stress cannot be overstated. These beneficial compounds not only slow down the aging process, but also enhance the body's ability to recover from physical exertion. Various supplements, including Beta Alanine, BCAAs, Creatine, Flavonoid Root, Glutamine, and Protein, each offer distinct benefits in supporting muscle growth, improving athletic performance, and promoting quicker recovery. The incorporation of these supplements into one's regimen can effectively bridge the nutritional gap left by processed foods. A preventive strategy, emphasizing a diet rich in antioxidants and high-quality supplements, holds the key to optimal health and longevity. As the saying goes, 'an ounce of prevention is worth a pound of cure'.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6591) Why Dextrose is Important for Athletes and Bodybuilders 
Date:
October 10, 2022 02:17 PM
Dextrose, also known as glucose, is a simple sugar (monosaccharide) that is the primary source of energy for the body. It is important for athletes because it stimulates the body to drive, not only glucose, but amino acids and other nutrients into cells. This makes energy readily available to working muscles and helps to maintain glycogen stores. In addition, dextrose also helps to make important nutrients, such as creatine and branched-chain aminos, available for use by muscle tissue. From an athletic performance perspective therefore, it can help fuel intense activity, maintain exercise endurance, and support recovery from exercise. How Dextrose Works Dextrose enters the bloodstream rapidly after being consumed and raises blood sugar levels quickly.* Insulin is then released by the pancreas in order to shuttle glucose into cells for use or storage.* Glucose is stored in the liver and muscles in the form of glycogen; when these stores become depleted during exercise, blood sugar levels fall and fatigue sets in.* Dextrose can help delay this fatigue by replenishing glycogen stores and keeping blood sugar levels elevated.* Dextrose And Creatine oppose each other hormonally; when insulin levels are elevated via carbohydrate consumption, creatine uptake into muscle cells is inhibited.* Conversely, when blood sugar levels are low (and insulin levels along with them), creatine uptake is enhanced.*Deoxyglucose acts as a transport vehicle for creatine, driving more of it into muscle cells where it can be used for energy production and protein synthesis – two key processes for supporting muscle growth.* Therefore, when combined with creatine, dextrose can further enhance its efficacy. *BCAAs are essential amino acids that must be obtained through diet since they cannot be produced by the body; of the three BCAAs (Leucine, isoLeucine, and valine), Leucine is the most anabolic.*Leucine seems to work best when consumed with carbohydrates; when carbs and Leucine are consumed together they stimulate insulin release – an anabolic hormone that promotes protein synthesis as well as drives amino acids and other nutrients into cells where they can be used or stored for future use..* Therefore, dextrose can help enhance the anabolic effects of Leucine consumption. In Summary: Dextrose is a simple sugar that has many benefits for athletes. It helps to fuel intense activity, maintain exercise endurance, support recovery from exercise, and delay fatigue. It also helps to make important nutrients like creatine and branched-chain aminos more available for use by muscle tissue. If you are an athlete who wants to perform at your best, make sure you include dextrose in your diet.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6495) Moms, add more leucine and omega-3s to your diet to boostantioxidant levels in your children's liver
Date:
April 22, 2019 04:16 PM
When you have an imbalance of antioxidants within your system, this often leads to oxidative stress. An increase in oxidative stress unfortunately leads to many forms of cancer. Research has emerged that showed leucine and omega-3's have the ability to fight off this oxidative stress by increasing the amount of antioxidants that are found in the liver. Both of these can be found in the form of a nutritional supplement at most mainstream health and wellness stores. Key Takeaways:
"Expectant mothers need a wide range of nutrients for them and their child to stay healthy." Read more: https://www.naturalnews.com/2019-02-27-moms-add-more-leucine-omega-3s-to-your-diet.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6148) Whey protein supports recovery from muscle loss among the elderly
Date:
March 27, 2019 10:31 AM
Whey protein is good for building muscle especially in the elderly. Studies have shown that whey protein can help elderly people build lost muscle from long hospital stays or illness. Lack of strength in the elderly can affect their balance and the ability to perform simple tasks. A controlled study of sixteen men and fifteen women between the ages of sixty-five and eighty, were given whey protein or collagen for five weeks. During the study there was no difference between the two, but after the study, whey proved to recover more muscle than collagen. The right supplements can help keep you healthy when paired with a healthy diet and exercise. Key Takeaways:
"A study published in the American Journal of Clinical Nutrition has found that whey protein can help seniors rebuild lost muscle from inactivity linked to illness or long hospital stays." Read more: https://www.naturalnews.com/2019-01-26-whey-protein-supports-recovery-from-muscle-loss-elderly.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6096) Leucine: The Muscle-Building Amino Acid Your Body Needs
Date:
June 23, 2018 09:54 AM
Leucine is a branched chain amino acid that is vital to building muscle, and can help to keep fat and blood sugar under control and prevent muscle deterioration in older athletes. It also has a role in promoting muscle recovery. Good dietary sources of leucine include grass-fed beef, venison, elk, tuna, chicken, lentils, wheat germ, hemp seeds, spirulina, and especially eggs. Leucine, like other branched chain amino acids, can only be ingested, not produced in the body. Key Takeaways:
"Keep reading for what you need to know about this branched-chain amino acid and how it can affect your health." Read more: https://draxe.com/leucine/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5643) Can L-Leucine Help Glucose Metabolism And Insulin Function?
Date:
June 02, 2014 08:54 AM
What is a Leucine
What does Leucine do L-Leucine has direct bearing on the amount of insulin produced. L-Leucine will stimulate the amount of insulin produced by the pancreas. One of the ways in which it influences the amount of insulin produced is by enhancing glutaminolysis by allosterically activating GDH (glutamate dehydrogenase). Benefits of Leucine Increased insulin levels have a major implications on glucose metabolism. Increased insulin level will directly result into faster glucose absorption into the blood stream. Increased glucose metabolism prevents the body from using lean muscles to supply energy during workouts. Unlike isoLeucine and valine, L-Leucine are converted to glucose slowly and thus you can have sustained energy for long. It is also very effective in muscle building. By stimulating insulin release and glucose metabolism, it enables key nutrients such as amino acids, Creatine and glucose to enter muscle cells. Since insulin will stimulate rapid muscle synthesis while inhibiting protein breakdown, L-Leucine will build lean muscle mass with a short period. L-Leucine is alternative to steroids, it is safer and its effects are lasting. During workouts, it supports oxidative metabolism in muscles and decrease protein degradation. If you are looking for the best way you can build muscle mass and strength without adverse effects, L-Leucine is premier supplement. Apart from building muscle, l-Leucine will also improve brain functions. You can take more workouts. L-leusine supplement has been used by many body builders and has been proved beyond doubt to be effective supplement. If you have been wondering if l-Leucine help glucose metabolism and insulin function, no doubt it is can. You can also red more by visiting //www.livestrong.com/article/261185-what-are-the-functions-of-Leucine/ //www.ncbi.nlm.nih.gov/pmc/articles/PMC2969169/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3131) L-Leucine as an essential Amino Acid
Date:
May 31, 2014 06:54 AM
L-Leucine is a a-amino acid with the chemical formulae HO2CCH(NH2)CH2CH(CH3)2. It is a hydrophopic amino acid to its aliphatic isobutyl side chain. L-Leucine is an essential amino acid since the human body can’t synthesize it, and it therefore must be ingested. What is an essential amino acid These are the amino acids that can’t be synthesized by the body of the organism hence it must be supplied in the diet. These amino acids is important not because they are important than others, but simply because the body can’t synthesize them. Phenylalanine, L- Leucine, Valine, Tryptophan, Threonine, meyhionine, iso - Leucine, lysine and histidine are some of amino acids regarded as essential for humans beings. The main difference between essential and non-essential amino acids is somehow since some proteins can be synthesized from others. The sulfur containing amino acids such as L-Leucine may sometimes be referred to as an essential amino acid. Effects of L-Leucine deficiency Majority of amino acids are important in the human diet. An experiment carried out by William Cummings Rose showed that lack of L-Leucine results to symptoms of exhaustion, nervousness and dizziness. Results further showed that these symptoms were encountered to lesser extent whenever human subjects were deprived of an essential amino acid. In plants and other micro-organisms, L-Leucine is synthesized from pruvic acid by several enzymes. These enzymes include: · a-Isopropylmalate synthase · L-Leucineaminotransferase · a-Isopropylmalate isomerase · Acetolactate synthase · Acetohydroxy acid isomeroreductase · Dihydroxyacid dehydratase Importance of L- Leucine L-Leucine is used by the adipose tissue, liver and the muscle. In muscle tissue and adipose L-Leucine is used in the formation of sterols. Ironically the combined usage of L-Leucine in the muscle and adipose is seven times greater than its use in the liver. L-Leucine is also used in stimulation of the muscle protein synthesis. In dietary , L-Leucine is used in to slow down the degradation of muscle tissue by increasing the synthesis of muscle proteins in aged rats however this does not work in elderly men. L-Leucine helps you lose weight and spare muscle when dieting. However L-Leucine can’t be associated as the main reason in muscular growth for the entire populatin. L-Leucine activates the mammalian target that regulates the growth cells in rats. Negative effects of L- Leucine L-Leucine cause neurologic complications which may be fatal if not control in time. Studies also show that over activity of the liver is caused by taking L-Leucine supplement, excess L-Leucine may also cause pellagra, whose symptoms include dermatitis, diarrhea, dementia and eventually death.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3130) ROLE OF BRANCH CHAINED AMINO CIDS IN MUSCLE GROWTH AND ATHLETIC PERFOMANCE
Date:
January 20, 2014 09:06 AM
Amino Acid
Leucine, IsoLeucine and Valine are Branched Chained essential Amino Acids(BCAA). These three amino acids account for 35% of the essential amino acids in muscle protein and 40% of the essential amino acids required by humans. Due to their importance, dietary supplementation of these amino acids has become quite common due to their beneficial effects. BCAAs help burn patients to recover faster as the amino acids in high concentration provide the material for the cells to repair themselves at a faster rate. At the same time, BCAAs help in managing diabetes Are very popular due to their many functions in the body of an athlete. This is because unlike other amino acids, it is metabolized in muscle tissue, not in the liver thus it has a more direct effect on the muscles than other amino acids. These functions include:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2974) What are the Essential Amino Acids we must get from our Diet to Survive?
Date:
August 17, 2011 12:13 PM
Amino acids or the building blocks of protein are very important in overall functioning of the body. Proteins, to mention, are responsible for the build up of most of our body parts specifically our muscles, ligaments, tendons, organs, tissues, glands, nails and hair. Moreover, the repair and preservation of those parts still rely on proteins. Amino acids can be of two different forms which are the non-essential and essential. On this selection, we will be focusing more on the latter. Essential amino acids are those which cannot be produced by the body therefore it has to be supplied through our diet. This category of amino acids includes tryptophan, lysine, methionine, valine, Leucine, isoLeucine, threonine and phenylalanine. Tryptophan, which is a precursor to serotonin and melatonin, can be acquired from peanuts, meat, turkey, fish, milk, dried dates, cottage cheese, banana, oats and chocolates. A deficiency of this can bring up serious neurological problems, depression, anxiety and sleeping difficulties. Another essential amino acid is methionine. The production of sulfur and other compound needed for a healthy growth and metabolism depends on the presence of this amino acid. Fish, whole grains and dairy are its sources. Lysine, which is effective in the treatment and prevention of herpes, is present in soybeans, green beans, lentils, spinach and amaranth. Low levels of lysine can also compromise the levels of niacin and this leads to pellagra. Tissue healing, muscle metabolism and keeping the equilibrium of nitrogen levels in our body are the functions of valine. It has proven to be efficient in the treatment of liver and gallbladder disorders. Deficiencies that results from drug addiction are can also be reversed by this amino acid. Its sources are peanuts, soy proteins, dietary products, grains, meat and mushrooms. Leucine can be obtained from chicken, fish, cottage cheese, lentils, peanuts and sesame seeds. It functions in muscle protein build up and is the main medium in tissue building process. Inability to acquire such makes a person prone to protein wasting since Leucine, together with valine and isoLeucine, serves as energy and protein reservoirs. In boosting energy levels, blood sugar regulation, muscle build - up and repair as well as hemoglobin development, isoLeucine has shown its relevance. Its dietary sources are fish, poultry, beef, dairy, eggs, lentils, seeds, soy, almonds and wheat. IsoLeucine deficiencies may result into neurological disturbances such as confusion, depression, irritability, fatigue, headache and dizziness. Threonine is significant in synthesis of antibodies. Beans, nuts, seeds, dairy, poultry, eggs and beef are rich in threonine. A low level of this amino acid causes disorders of the skin and weakness. Adrenaline and noradrenalin which are stimulates the central and peripheral nervous system requires phenylalanine to perform their function. Phenylalanine can be acquired from peanuts, seeds, almonds, lima beans and dairy. Liver damage, weakness, skin lesions, lethargy and slowed growth are results of its deficiencies. In summary, our body needs networks of essential amino acids for its proper functioning. Eating healthy foods and living a healthy lifestyle is the secret towards maintaining your optimum general health.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2396) Strengthen The Liver and Kidneys With Leucine
Date:
April 27, 2009 02:08 PM
L-Leucine is an amino acid that is used by the body to fuel exercise and muscle-building to provide you with that athletic edge that gets you ahead of your opponents. It does so in a number of ways, none of them specifically by the direct generation of energy as such. It is also an essential amino acid, since it cannot be manufactured by your body and hence must be taken as a supplement or as part of your diet. Foods rich in Leucine include nuts, whole wheat products such as wholemeal bread, and brown rice. It is a hydrophobic amino acid, meaning that it does not like water. It is also one of three essential branched chain amino acids, the other two being L-valine and L-isoLeucine, and offers many benefits to athletic performance that shall be discussed below It also helps to preserve the body's stores of glycogen, used as an emergency energy source. Other than these properties, it possesses others, such as the maintenance of the nitrogen balance in the body. So how does it work to fuel your body while you are exercising? The answer is not as you might think. L-Leucine doesn't increase your energy levels as creatine does when it elevates your ATP (adenosine triphosphate) levels. ATP is the molecule of energy that is synthesized in your body cells, and is then converted back to ADP, the diphosphate, with the release of energy in the form of muscular contractions. This amino acid is what is referred to as a 'limiting' substance, in that the other amino acids cannot do their jobs in your body unless you have sufficient L-Leucine in proportion to them. Specifically, you need two parts of L-valine and two parts of L-Leucine to one part of L-isoLeucine for optimum usage of the food that you eat. Therefore you cannot just take the supplement without considering how much should be taken to ensure this balance. Excess will be wasted and a deficiency would fail to make proper use of the protein content of your food. If you suffer from a deficiency, therefore, your body cannot make best use of the protein in your diet to the extent that muscle tissue will not be generated during exercise. In fact it causes catabolism, or the breakdown of muscle tissue, resulting in a loss of performance and possible increase in fatty tissue as opposed to lean muscle. The only way to build muscle is take in sufficient nitrogen in the form of amino acids and protein, along with L-Leucine to put that protein to best use. One of the major properties of L-Leucine is in stimulating the synthesis of skeletal muscle tissue and by using a supplement, the protein balance can be positive after a workout. It has been shown that this protein balance is generally negative until specifically L-Leucine is consumed. The way it works is to activate a muscle-generating pathway known as mTOR (mammalian Target of Rapamycin). mTOR is normally activated when the levels of ATP in the muscle cells is high, and when these levels drop then mTOR is deactivated. The activity of mTOR is sensitive to the concentration of L-Leucine, and when the concentration of the amino acid in the body rises it informs mTOR that the protein in the diet is sufficient to manufacture skeletal muscle tissue, and so mTOR s activated. Exactly how this is done is unknown, but is a fact the mTOR depends upon both L-Leucine concentration and also ATP levels. This amino acid also decreases catabolism through a number of different mechanisms, one of which involves increasing insulin levels. In fact, when insulin and L-Leucine levels increase at the same time, there is a synergy that promotes the synthesis of new protein. Not only that, but the response of insulin to the presence of carbohydrates is enhanced, this resulting in an enhancement of your body's metabolism. The amino acid can also be used to help those suffering from kidney and liver problems because it increases liver protein synthesis. It is therefore a useful adjunct both to diabetics and those suffering from liver and kidney disease. However, because L-Leucine is an essential amino acid with so many important properties, a deficiency can have specific consequences. Catabolism has been stated earlier as one such reaction to a deficiency, and others include decreased energy levels and irregularities in the levels of blood sugar. Everything about this substance is not good however, and when taken by itself in excess, it can reduce the amount of the other amino acids in the blood, particularly of the other two branched chain amino acids (BCAAs). This in turn upsets the balance of amino acids, and reduces further the ability of the body to produce muscle tissue until a balanced supplement is taken. Leucine also helps to maintain the nitrogen balance. It is essential for the human body to maintain a positive nitrogen balance, and L-Leucine supports this. In fact, one study has demonstrated that after 12 hours infusion with L-Leucine, nitrogen balance was improved by as much as 23%. A supplement alone is not always sufficient to maintain a positive nitrogen balance. It is generally essential that you rest your body for a sufficient length of time to allow protein to be generated. If you don't take the required amount of rest, a surplus of protein could be used to maintain energy levels rather than replace lost protein and maintain a good nitrogen balance. A positive nitrogen balance is essential for the generation of muscle tissue, such as in bodybuilding for example, since all proteins contain nitrogen and the net nitrogen intake must exceed the excretion rate. Not in gaseous form, of course, but in the intake of amino acids and proteins. The more positive your nitrogen balance is, the faster you will recover after exercise. It is essential for anabolic exercise. L-Leucine, therefore, is a supplement that can help to maintain your current muscle mass while undergoing strenuous exercise, in addition to increasing it while resting. It offers other health benefits, one being helping to maintain clarity of thought in the aged. However, it is for its effect on muscular build-up and the athletic edge that provides that the supplement is most commonly taken.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1997) Broken Cell Chlorella - Single Celled Micro alga
Date:
April 21, 2008 05:06 PM
Chlorella is what is known as a micro alga, a single celled vegetable organism that grows in fresh water. Microalgae are microscopic species of plant life that are likely responsible for the biological evolutionary history of our planet. Most people associate algae with seaweed: marine plant life. However, this is a restricted view since algae are also common on land, although are rarely conspicuous and still require an aqueous environment if not necessarily a salt water ocean. The reason for this is that algae have no vascular tissue to draw moisture up into the body of the plant as terrestrial plants do, and they tend to be found in tropical regions, on snow in areas of the Arctic and also on exposed areas of stone and rock in symbiosis with fungi in the form of lichens. They can also be found in freshwater ponds and rivers, and chlorella is one of these. Its scientific name is Chlorella pyrenoidosa, and it occurs worldwide. It is said to have the highest concentration of chlorophyll of any other known plant in addition to its other highly nutritional content. The superlatives are almost limitless for such a small plant that most of the general population is unaware of. It is the first plant known to have a true nucleus, it has been around for about two and half billion years, and it can multiply itself fourfold making it the fastest growing species of plant known on earth. It beats other fast-growing algae and bamboo out of site. So what of its nutritional content? It is believed by NASA to be the ultimate foodstuff for long-term travel in space and an ideal crop for colonizing communities. Were a space community to be established on Mars, chlorella would be the first to be cultivated under these big glass domes we all see in the movies! It is more than just a foodstuff though; it is also the most powerful known natural detoxifier for the human body, which makes it practically the ideal food. Why is this? If any food deserves to be referred to as a ‘superfood’ it is chlorella. It consists of over 60% bioavailable protein, and contains six members of the vitamin B complex (1, 2, 3, 5, 6, 12) and also vitamins A, C, E and K. It is therefore very high in antioxidants and excellent for destroying free radicals as soon as they are formed, and before they can cause problems such as atherosclerosis and excessive cell damage. It also contains more than its fair share of minerals such as calcium, manganese, magnesium, phosphorus and zinc, and also iodine, folic acid and a high proportion of iron. That is not all: it contains many more nutrients essential for a healthy life, but above all chlorella contains all eight essential amino acids. Human biochemistry and metabolism need 20 amino acids to function properly, twelve of which can be manufactured by the liver from these eight: Leucine, isoLeucine, lysine, methionine, phenylalanine, threonine, tryptophan and valine, and sometimes serine is added. These are called the essential amino acids from which all the others that your body needs can be manufactured. Amino acids are needed to build proteins and DNA, manufacture body cells, repair damaged tissue, help the immune system to protect you from invading bacteria and viruses, ensure that the oxygen you breathe gets to the cells where it is needed to sustain life and carry out many other functions besides. Without them you could not exist. Chlorella contains five times more protein and amino acids than eggs do. The Chlorella Growth Factor or CGF is a combination of these amino acids, together with nucleic acids, carbohydrates and peptides that have not yet been completely characterized. The CGF promotes the growth of body cells, and stimulates cell repair in a way not seen before in any other food. It has been shown to promote the growth of children in a natural and safe way. Not only this, but it has been found not to promote the growth of diseased or cancerous cells, only healthy ones. The fact that that this accelerated growth does not happen with adults indicates that the Chlorella Growth Factor supports the natural growing process, although in adults it has been seen to accelerate the repair of damaged body tissue. Chlorella also appears to strengthen the immune system, and researchers have found the presence of a polysaccharide in the cell walls of the microalgae that acts with CGF to produce an interferon that protects the helper cells that aid macrophages to destroy invading bacteria and viruses. It can help our resistance to influenza, choryza (common cold), fungi such as candida and many other forms of invasion by foreign agents into our bloodstream. The detox effect of chlorella is largely contained within its cell walls that can bind with persistent toxic substances such as DDT, and bind with heavy metals to safely remove them from the body. In fact it is the ideal anti-toxin for life in today’s environment, full of vehicle exhaust fumes, pesticides and other chemical emissions. It has been claimed to be able to remove mercury from the body, but this has not been established. Probably the only problem with the ingestion and the efficiency of the body to use Chlorella to its full extent is the strength of the cell walls. Chlorella has very strong cell walls, which could also account for the concentration of nutrients within them. the traditional method to overcome this was to mill them using small glass or ceramic beads to break the cell walls down, but the Japanese have come up with a more effective means. High frequency sound waves are used to break the cell walls down supersonically, a technique known as ‘cracking’, and once cracked the cells can release up to 65% of its nutrients, compared to the 50% of the milling method. The nutritional content of single celled microalgae such as chlorella is amazing, and if the was only one food that you were able to eat, then this would be it. There is no other known species of plant or animal life that provides the range of vitamins, minerals, proteins and amino acids that chlorella does, and it truly is the king of all superfoods.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1764) Which Protein Is Best For You?
Date:
January 18, 2008 11:16 AM
If you are physically active and taking supplements but still cannot seem to get the energy back in your body and brain, then it’s time to look at how much and what kind of protein you are getting. Even though dieters have been using high-protein diets for years, many are unaware of how much protein they actually need and how critical it is to their overall health. Low-protein diets can be lacking greatly in a lot of essential nutrients such as zinc, iron, manganese, chromium, copper, and others. This deficiency can cause illness and fatigue. Protein deficiency leads to difficult recovery from exercise, feeling tired, frequent colds, poor hair or nails, and a cessation in menstrual period for women, which may sound pleasant but is potentially dangerous. People of all ages are not aware of how much their protein needs change as they increase exercise. As your activity increases, so does your protein needs. Protein is important in your body because every single cell in the body is made up of proteins. Protein is also essential for muscle building, producing red blood cells, the production of various enzymes and hormones, and good hair, nails, and skin. Our immune systems are almost all protein based, so providing our body with protein means that we can fight colds and other infections better. Proteins are also needed in our body to repair muscle damage that occurs during mild exercise. Protein is made from a chain of amino acids and our body cannot make some of these amino acids, which means that they need to be found in our diet. There are eight amino acids that our body cannot make and must be found in our diet every day. These include: isoLeucine, Leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine. Although it is nice to know which amino acids are essential, it is even more important to know where you can find these amino acids because your muscles and body need them on a daily basis. Since proteins are constantly being broken down, it is necessary to get some every day. It is suggested that women aged 19 to 70 need 46 grams of protein per day, while men of the same age need 56 grams. Now that you know that protein is essential to your life, what kind of protein is actually needed? Even though protein can be found in a good diet by simply eating meat, nuts, eggs, and other foods, many of us with busy lives need a quick and convenient source of protein. At a health food store, your choices are soy, casein, whey, and egg. Although the classic protein source is whey protein, the problem is that even though it has a high amount of useable amino acids, some people don’t like it or have a hard time taking it. Other proteins like soy and casein don’t have the complete amino acid content that your body is looking for. With all the different forms of protein available one might wonder which is best? Egg white is the perfect protein source. Egg whites contain more than half the protein of an egg and are also rich in chlorine, niacin, potassium, magnesium, riboflavin, selenium, vitamin K, and sulfur. Additionally, egg whites have a high amount of protein but exclude the cholesterol and sodium found in the yolk. Egg white protein is considered almost perfect because human requirements for amino acids and the amino acids contained in eggs are almost identical. Eggs are also one of the well-tolerated proteins, as over 90 percent of the protein of eggs is digested into the individual amino acids that your body needs. Egg white protein is one of the few products on the market that taste good without the added artificial flavors, colors, or additives.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1695) Protein And Its Role In Bodily Functions
Date:
November 09, 2007 05:00 PM
Protein is an essential organic compound composed of 20 or more amino acids which are joined by peptide bonds. Proteins serve as structural material such as connective tissue, and hair (i.e. collagen and keratin) can function as enzymes and hormones, as transporters of essential substances such as oxygen, antibodies, or regulators of gene expression. The importance of protein cannot be overstated in its effects on overall health regardless of age. Dieters using the low-protein diet can be seriously lacking in many essential nutrients including minerals such as zinc, iron, manganese, chromium, copper, etc. These deficiencies can lead to chronic illness, fatigue and make mental function more difficult. In order to fight sickness and disease, our immune systems need to be in optimum performance. Something you may not have realized but our immune system are almost all protein based. Providing the body with the correct proteins is like providing the proper building blocks of the immune system and can help to fight the common cold and infections better. Proteins are also used to repair muscles during exercise. There are eight essential amino acids which the body cannot manufacture and which we must derived from our diet each day. The essential amino acids are (i) isoLeucine, (ii) Leucine, (iii) lysine, (iv) methionine, (v) phenylalanine, (vi) theronine, (vii) tryptophan, and (viii) valine. With this list of proteins it is possible to determine where we can find these amino acids and incorporate them into our diet. We need protein in our diet on a daily basis, especially for muscle function which requires a particular mix of amino acids which are not found in many food sources. For example, to increase muscle mass, you need glutamine, carnitine, taurine, and arginine amino acids. Now that we know we need protein daily in our diet and that protein is essential to life. So the next question you may have is what kind of proteins are the best? Quality proteins found in your local grocery store can be found in meat, nuts, eggs, and other foods. If you turn to your local health food store, look at soy, casein, whey and egg proteins. The type of protein you take will depend upon what you are capable of eating, i.e. taste. Some people have trouble eating whey protein, while others cannot pallet egg protein.
The best protein found in nature however is derived from egg whites. Egg proteins are not only complete in its supply of what the body needs, the egg is rich in chlorine, niacin, potassium, magnesium, riboflavin, selenium, vitamin K, sulphur, and omega-3. An added bonus to eating egg whites is the lack of cholesterol and sodium in the yoke. Eggs are also one of the most tolerable proteins in the human body where over 90 percent of the proteins derived from eggs is digested into the individual amino acids our bodies need. By eating egg derived protein you are essentially supplying the body with the raw materials it needs for proper function. So, if you have been troubled by fatigue, poor hair and nails the answer may be to increase your protein intake or try an all natural egg white protein for three to four weeks and see what a difference it will make in your health and appearance
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1623) Enhanced Muscle Growth with Free Form Amino Acids
Date:
September 07, 2006 01:30 PM
Notably L-Leucine, L-Valine, and L-IsoLeucine prevent muscle tissue breakdown during exercise. Free form amino acids accelerate muscle tissue healing and growth by providing and specific amino acid profile where they are needed, directly in muscle tissue. The result is faster muscle and strength gains, as well as enhanced recovery.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1374) HAWAIIAN NONI (Morinda citrifolia)
Date:
July 11, 2005 08:50 PM
INTRODUCTION In a time when we are more concerned than ever with issues of health, a tried and true tropical herb called noni needs t o be added t o our list of the best natural remedies. It susage over hundreds of years supports it s description as a veritable panacea of therapeutic actions. At this writing, noni continues to accrue impressive medicinal credentials, and its emergence as an effective nat ural healing agent is a timely one. Amidst rising cancer rates, the high incidence of degenerative diseases like diabetes, and the evolution of ant ibiotic resist ant bacteria and new viral strains, herbs like noni are sought after for their natural pharmaceutical properties. Unquest ionably, all of us want to know how to:
Genus Rubiaceae Common Names Indian Mulberry (India), Noni (Hawaii), Nono (Tahiti and Raratonga), Polynesian Bush Fruit, Painkiller Tree (Caribbean islands), Lada (Guam), Mengkudo (Malaysia), Nhau (Southeast Asia), Grand Morinda (Vietnam), Cheesefruit (Australia), Kura (Fiji), Bumbo (Africa) Note: This is only a small sampling of vernacular names for Morinda citrifolia. Almost every island nation of the South Pacific and Caribbean has a term for this particular plant . This booklet will refer to the herb mainly as “ noni” or M. citrifolia, and is referring primarily to Hawaiin noni. Parts Used The parts of the noni plant most used for their medicinal and nutritional purposes are the fruit, seeds, bark, leaves, and flowers. Virtually every part of the noni plant is utilized for its individual medicinal properties; however, it is the fruit portion that is regarded as its most valuable. The seeds have a purgative action, the leaves are used to treat external inflammations and relieve pain, the bark has strong astringent properties and can treat malaria, the root extracts lower blood pressure, the flower essences relieve eye inflammations and the f ruit has a number of medicinal actions. Physical Description Morinda citrifolia is technically an evergreen shrub or bush, which can grow to heights of fifteen to twenty feet . It has rigid, coarse branches which bear dark, oval, glossy leaves. Small white fragrant flowers bloom out of cluster-like pods which bear creamy-white colored fruit. The fruit is fleshy and gel-like when ripened, resembling a small breadf ruit . The flesh of the fruit is characterist ically bitter, and when completely ripe produces a rancid and very dist inctive odor. Noni has buoyant seeds that can float formont hs in ocean bodies. The wood of the inflammatory, astringent, emollient, emmenagogue, laxative, sedative, hypotensive (lowers blood pressure) , blood purif ier, and tonic. Chemical Constituents Noni has various chemical constituents. First, it has an impressive array of terpene compounds, three of which—L. Asperuloside, aucubin, and glucose— have been identified by their actyl derivatives. Both caproic and caprylic acids have been isolated.1 Second, bushfruits, a category of which noni fruit is a member, are also considered a good source of vit - amin C.2 Third, Hawaiin noni has been linked to the synthesis of xeronine in the body which has significant and widespread health implications. Last , the alkaloid cont ent of the noni fruit is thought to be responsible for its therapeutic actions. Alkaloids exhibit a wide range of pharmacological and biological act ivitiesin the human body. They are nitrogencontaining organic compounds which can react with acids to form salts and which are the basis of many medicines. The following is an in-depth chemical analysis of each plant part and it s chemical constituents.
FLOWER
FRUIT
discovered an alkaloid in the Hawaiin noni fruit which he calls proxeronine and which he believes has appreciable physiological actions by acting as a precursor to xeronine, a very crucial compound (see later sections) . In addition, a compound found in the fruit called damnacanthol is believed to help inhibit cert ain viruses and cellular mutations involved in cancer. ROOT AND ROOT BARK
Pharmacology Recent surveys have suggested that noni fruit exerts antibiotic action. In fact, a variety of compounds which have antibacterial properties (such as aucubin) have been identified in the fruit.5 The 6-Dglucopyranose pentaacet ate of the fruit extract is not considered bacteriostatic.6 Constituents found in the fruit portion have exhibited ant imicrobial action against Escherichia coli, Salmonella typhi (and other types) , Shigella paradysenteriae, and Staphylococcus aureaus. Compounds found in the root have the ability to reduce swollen mucous membrane and lower blood pressure in animal studies. Proxeronine is an alkaloid constituent found in Hawaiin noni fruit which may prompt the production of xeronine in the body. It is considered a xeronine precursor and was discovered in noni fruit by Dr. Ralph M. Heinicke. He has theorized that this proenzyme can be effective in initiating a series of beneficial cellular reactions through its involvement with the integrity of specific proteins. He points out that tissues contain cells which possess certain recept or sites for xeronine. Because the reactions that can occur are so varied, many different therapeutic actions can result when xeronine production escalates, explaining why Hawaiin noni is good for so many seemingly unrelated disorders. Damnacanthol is another compound contained in the fruit of the Hawaiin noni plant which has shown the ability to block or inhibit the cellular function of RAS cells, considered pre-cancerous cells. Body Systems Targeted The following body systems have all been effec-freeze-dried capsules, dehydrated powder or fruit, and oil. Noni plant constituents are sometimes offered in combination with other herbs. Some products contain a percent age of the fruit, bark, root and seeds for their individual therapeutic properties. Satety Extracts of M. citrifolia are considered safe if used as directed; however, pregnant or nursing mothers should consult their physicians before taking any supplement . High doses of root extracts may cause constipation. Taking noni supplements with coffee, alcohol or nicotine is not recommended. Suggested Uses Ideally, noni extracts should be taken on an empty stomach prior to meals. The process of digesting food can interfere with the medicinal value of the alkaloid compounds found in Hawaiin noni, especially in its fruit . Apparently, stomach acids and enzymes destroy the specific enzyme which frees up the xeronine compound. Take noni supplements without food, coffee, nicotine or alcohol. Using supplements that have been made from the semi-ripe or light - green fruit is also considered preferable to the ripe, whit ish fruit . NONI: ITS USE AND HISTORY Noni is a tropical wandering plant indigenous to areas of Australia, Malaysia and Polynesia. It is considered native to Southeast Asia although it grows from India to the eastern region of Polynesia. Morinda citrifolia has a long history of medicinal use throughout these areas. It is thought to be the “most widely and commonly used medicinal plant prior to the European era.” 7 Centuries ago, the bushfruit was introduced to native Hawaiians, who subsequently called it “noni” and considered its fruit and root as prized medicinal agents. Among all Polynesian botanical agents of the 19th and 20th centuries, Hawaiin noni has the widest array of medical applications. Samoan and Hawaiian medical practitioners used noni for bowel disorders (especially infant diarrhea, constipation, or intestinal parasites) , indigestion, skin inflammation, infection, mouth sores, fever, contusions and sprains. Hawaiians commonly prepared noni tonics designed to treat diabetes, stings, burns and fish poisoning.8 The herb’s remarkable ability to purge the intestinal tract and promote colon health was well known among older Hawaiian and Tahitian natives and folk healers. Interestingly, field observations regarding its repu-remarkable healing agent . Wonder Herb of Island Folk Healers Common to t he thickets and forests of Malaysia and Polynesia, and the low hilly regions of the Philippine islands, noni has been cultivated throughout communities in the South Pacific for hundreds of years. Its Hawaiian use is thought to originate from inter-island canoe travel and settlement dating to before Christ . Its hardy seeds have the ability to float which has also contributed to its distribution among various seacoasts in the South Pacific region. Historical investigation has established the fact that some of Hawaii’s earliest settlers probably came viaTahiti. For this reason, Tahitian herbal practices have specific bearing on the herbal therapeutics of islands to the nort h. The very obvious similarities between the Hawaiian vernacular for herbal plants like noni and Tahitian names strongly suggests the theory of Polynesian migrations to Hawaii. Cultures native to these regions favored using Morinda citrifolia for treating major diseases and ut ilized it as a source of nourishment in times of famine.9 Noni fruit has been recognized for centuries as an excellent source of nutrition. The peoples of Fiji, Samoa and Rarat onga use the fruit in both its raw and cooked forms.10 Traditionally, the fruit was propicked before it was fully ripe and placed in the sunlight . After being allowed to ripen, it was typically mashed and its juice extracted through a cloth. Noni leaves provided a veget able dish and their resiliency made them desirable as a fish wrap for cooking. Noni’s Medical Reputation Elaborate traditionalrituals and praying rites usually accompanied the administration of noni. Int erestingly, cultures indigenous to the Polynesian islands had a significant understanding of their flora. For example, native Hawaiians maint ained a folkmedicine taxonomy t hat was considered second to none.11 Noni was not only used for medicinal purposes but for its food value, for clot hing and for cloth dyes as well. Research indicates that noni was among the few herbal remedies that islanders considered “ tried and true.” In Hawaii, trained herbal practitioners reserved the right to prescribe plant therapies.12 Records indicate that Hawaiian medical practices were based on extensive and very meticulous descriptions of symptoms and their prescribed herbal treatments. Dosages were controlled and the collection and administration of plant extracts was carefully monitored.13 In addition to Morinda, it was not uncommon for these herbal doctors to also recommend using In regard to its application for common ailments, Hawaiians and other island communities traditionally prescribed noni to purge the bowel, reduce fever, cure respiratory infections such as asthma, ease skin inflammations, and heal bruises and sprains. In other words, noni was widely used and highly regarded as a botanical medicine. A Timely Reemer gence Today, the natural pharmaceutical actions of the chemical constituents contained in noni are scientif-ically emerging as valuable bot anical medicines. Tahitian “nono” intrigued medical practitioners decades ago; however, due to the eventual emergence of synthetic drugs, interest in this island botanical diminished until recent years. Ethnobot anists are once again rediscovering why Hawaiian people havet reasured and cultivat ed Morinda citrifolia for generations. Noni is now finding its way into western therapeutics and is referred to as “ the queen” of the genus Rubiaceae. Its ability to reduce joint inflammation and target the immune system have made it the focus of the modern scientific inquiry. Dr. Ralph Heinicke has conducted some fascinating studies on the chemical constituents of the Hawaiin noni fruit. His research centers on the proxeronine content of the fruit juice and how it profoundly influences human physiology. In addition, scientific studies investigating noni as an anti-cancer agent have been encouraging. It s conspicuous attributes and varied uses have elevat edits status to one of the best of the healing herbs. Today Morinda citrifolia is available in liquid, juice, freezedried capsules, or oil forms, and is considered one of nature’s most precious botanicals. TRADITIONAL USES OF NONI Throughout tropical regions, virtually every part of Morinda citrifolia was used to treat disease or injury. Its curative properties were well known and commonly employed. PatoaTama Benioni, a member of the Maoritribe from the Cook Islands and a lecturer on island plants explains: Traditionally Polynesians use noni for basically everything in the treatment of illness. Noni is a part of our lives. Any Polynesian boy will tell you he’s had exper ience with it . We use juice from its roots, its flowers, and its fruit... my grandmother taught me to use noni from the roots and the leaves to make medicine for external as well as internal use, and for all kinds of ailments, such as coughs, boils, diseases of the skin, and cuts.15 decoctions to stimulate delayed menst ruation.
XERONINE: THE SECRET OF NONI? One informed professional on the subject of noni is Dr. Ralph Heinicke, a biochemist who has researched the active compounds of noni fruit for a number of years. He discovered that the Hawaiin noni fruit contains an alkaloid precursor to a very vital compound called xeronine. Wit hout xeronine, life would cease. In Dr. Heinicke’s view, noni fruit provides a safe and effective way to increase xeronine levels, which exert a crucial influence on cell health and protction. His research suggests that the juice from the M. citrifolia fruit contains what could technically be considered a precursor of xeronine—proxeronine. This compound initiates the release of xeronine in the intestinal tract after it comes in contact with a specific enzyme which is also contained in the fruit . Because proteins and enzymes have so many varied roles within cell processes, the normalization of these proteins with noni supplemenation could initiate avery wide variety of body responses and treat many disease condit ions. Proteins are the most important catalysts found in the body. The beauty of obtaining a precursor to xeronine from the noni fruit is that the body naturally decides how much of this precursor to convert to xeronine. Disease, stress, anger, trauma and injury can lower xeronine levels in the body, thus creat ing a xeronine deficit . Supplementing the body with noni fruit is considered an excellent way to safely and naturally raise xeronine levels. It is the research and theories of Dr. Heinicke which have made the juice of the Hawaiin noni fruit a viable medicinal substance. He writes: Xeronine is analkaloid, a substance the body produces in order to activate enzymes so they can function properly. It also energizes and regulates the body. This par-ticular alkaloid has never been found because the body makes it, immediately uses it, and then breaks it down. At no time is there an appreciable, isolable amount in the blood. But xeronine is so basic to the functioning of proteins, we would die without it . Its absence can cause many kinds of illness.17 Because so many diseases result from an enzyme malfunction, Dr. Heinicke believes that using the noni fruit can result in an impressive array of curative applications. Interestingly, he believes that we manufacture proxeronine while we are sleeping. He proposes t hat if we could constantly supply our bodies wit h proxeronine from other sources, our need to sleep would diminish.18 NONI PROCESSING How an herb is processed is crucial to how beneficial it is: this is especially true of noni, with its unique enzymes and alkaloids. Morinda citrifolia should be picked when the fruit is turning from its dark green immature color to its lighter green color, and certainly before it ripens to its white, almost translucent color. Once picked, noni, like aloe, will denature extremely quickly due to its very active enzymes. After harvesting, it should swiftly be flash frozen. This is similar to what is done to fish caught at sea to keep them f esh. This stops it from losing its potency while not damaging any of its constituents. To process noni, freeze-drying is recommended. This removes only the water without damaging any of this miracle plant’s vital enzymes and other phytonutrients like xeronine and proxeronine. This pure high-quality noni fruit juice powder is then encapsu-has a very harsh taste and an extremely foul smell, similar to the fruit it self . Other methods of processing include thermal processing, dehydrat ion and air drying. Thermal processing is generally found in liquids, while the dehydrat ed noni is then milled and encapsulated. Unfortunately both methods utilize high heat (110+°F) , which can deactivate many of the vital compounds that make noni so import ant . Air-drying is effect ive without using damaging heat but has serious quality control problems for commercial production. MODERN APPLICATIONS OF NONI Overview Noni possesses a wide variety of medicinal properties which originat e from its differing plant component s. The fruit and leaves of the shrub exert antibacterial activities. Its roots promote the expulsion of mucus and the shrinkage of swollen membranes making it an ideal therapeutic for nasal congest ion, lung infect ions, and hemorrhoids. Noni root compounds have also shown natural sedative properties as well as the ability to lower blood pressure. Leaf extracts are able to inhibit excessive blood flow or to inhibit the formation of blood clots. Noni is particularly useful for its ability to treat painful joint conditions and to resolve skin inflammations. Many people drink noni fruit extracts in juice form for hypert ension, painful menstruation, arthritis, gastric ulcers, diabetes, and depression. Recent studies suggest that its anticancer activit y should also be considered. Concerning the therapeutic potential of the Hawaiin noni fruit, Dr. Heinicke writes: I have seen the compound found in noni work wonders. When I was still investigating its possibilities, I had a friend who was a medical research scientist administer the proxeronine to a woman who had been comatose for three months. Two hour safter receiving the compound, she sat up in bed and asked where she was. . . . Noni is probably the best source of proxeronine that we have today.19 Studies and surveys combined support the ability of noni to act as an immunost imulant, inhibit the growth of certain tumors, enhance and normalize cellular function and boost tissue regeneration. It is considered a powerful blood purifier and contributor to overall homeostasis. xeronine, which appears to be able to regulate the shape and integrity of cert in proteins that individually contribute to specific cellular activities. Interestingly, this effect seems to occur after ingestion, inferring that the most active compound of noni may not be present in uneaten forms of the fruit or other plant parts. Some practitioners believe that xeronine is best obtained from a noni fruit juice precursor compound. The enzymatic reactions that occur with taking the juice on an empty stomach are what Dr. Heinicke believes set cellular repair intomotion. Cancer A study conducted in 1994 cited the anticancer activity of Morinda citrifolia against lung cancer. A team of scientists from the University of Hawaii used live laboratory mice to test the medicinal properties of the fruit against Lewis lung carcinomas which were artificially transferred to lung tissue. The mice that were left untreated died in nine to twelve days. However, giving noni juice in consistent daily doses significantly prolonged their life span. Almost half of these mice lived for more than fifty days.20 Research conclusions state that the chemical constituents of the juice acted indirectly by enhancing the ability of the immune system to deal with the invading malig-nancy by boosting macrophage or lymphocyte activit y. Furt her evaluation theorizes that the unique chemical constituents of Morinda citrifolia initiate enhanced T-cell activity, a reaction that may explain noni’s ability to treat a variety of infectious diseases. 21 In Japan, similar studies on tropical plant extracts found that damnacanthol, a compound found in Morinda citrifolia, is able to inhibit the function of KRAS- NRK cells, which are considered precursors to certain types of malignancies.22 The experiment involved adding noni plant extract to RAS cells and incubating them for a number of days. Observation disclosed that noni was able to significantly inhibit RAS cellular function. Among 500 plant extracts, Morinda citrifolia was determined to contain the most effective compounds against RAS cells. Its damnacanthol content was clinically described in 1993 as “a new inhibit or of RAS function.” 2 3 The xeronine fact or is also involved in that xeronine helps to normalize the way malignant cells behave. While they are still technically cancer cells, they no longer function as cells with unchecked growth. In time, the body’s immune system may be able to eradicate these cells. Arthritis with arthritic disease. One link to arthritic pain may be the inability to properly or completely digest proteins which can then form crystal-like deposits in the joints. The ability of noni fruit to enhance protein digestion through enhanced enzymatic function may help to eliminate this particular phenomenon. In addition, the alkaloid compounds and plant met abolites of noni may be linked to its apparent anti-inflammatory action. Plant sterols can assist in inhibiting the inflammatory response which causes swelling and pain. In addition, the antioxidant effect of noni may help to decrease free radical damage in joint cells, which can exacerbate discomfort and degeneration. Immune System The alkaloid and other chemical compounds found in noni have proven themselves to effectively control or kill over six types of infectious bacterial strains including: Escherichia coli, salmonellatyphi (and other types) , shigella paradysenteriae, and staphylo - coccus aureaus.25 In addition, damnacanthol, was able to inhibitt he early antigen stage of the Epstein- Barr virus. The bioactive components of the whole plant, combined or in separate portions, have demonst rat - ed the ability to inhibit several different strains of bacteria. Anecdotal reports support this action in that noni seems particularly effective in shortening the duration of certain types of infection. This may explain why noni is commonly used to treat colds and flu. The chemical constituents found in noni and the possibility that they stimulate xeronine production— as well as initiate alkaloid therapy—may explain noni’s reputation for having immuno-stimulatory properties. Alkaloids have been able to boost phagocytosis which is the process in which certain white blood cells called macrophages attack and literally digest infectious organisms. Interestingly, the ant it umoraction of noni has been ascribed to an immune system response which involves stimulating T-cells. tropical regions during World War II learned of the fruit’s ability to boost endurance and stamina. Native cultures in Samoa, Tahiti, Raratonga and Australia used the fruit in cooked and raw forms. M. citrifolia is considered a tonic and is especially recommended for debilitated conditions. Antioxidant The process of aging bombards the body with free radicals which can cause all kinds of degenerative diseases. The xeronine theory promoted by Dr. Heinicke submit s t hat as our bodies age, we lose our ability to synthesize xeronine. To make matters worse, the presence of many environment altoxins actually blocks the production of xeronine as well. He believes that the proxeronine content of Hawaiin noni fruit juice can help to block these actions, thereby working as an antiaging compound.26 The phytonutrients found in noni assist in promot - ing cell nourishment and prot ect ion from free radicals created by exposure to pollution and other potentially damaging agents. In addition, Morinda citrifolia contains selenium, which is considered one of the best antioxidant compounds available. Diabetes While scientific studies are lacking in this particular application of noni, Hawaiians used various parts of the plant and its fruit to treat blood sugar disorders. Anecdotal surveys have found t hat noni is current ly recommended for anyone with diabetes. Pain Killer A 1990 study found that extracts derived from the Morinda citrifolia root have the ability to kill pain in animal experiments.27 Interest ingly, it was during this study that the natural sedative action of the root was also noted. This study involved a French team of scientists who noted a significant central analgesic activity in laboratory mice.28 Dr. Heinicke has stated, “Xeronine also acts as a pain reliever. A man wit h very advanced int est inal cancer was given three months to live. He began taking the proxeronine and lived for a whole year, pain-free.” 29 Skin Healing Agent One of the most prevalent hist rical uses of noni was in poultice form for cuts, wounds, abrasions, burns and bruises. Using its fruit extract for very serious burns has resulted in some extraordinary healing. Because skin is comprised of protein, it immediately responds to the presence of xeronine. burn site throught he direct application of a noni poultice is considered quite effective by Dr. Heinicke and his colleagues, who have studied enzymatic therapy. Concerning burns, he has written: I believe that each tissue has cells which contain proteins which have receptor sites for the absorption of xeronine. Certain of these proteins are the inert for ms of enzymes which require absorbed xeronine to become active. This xeronine, by converting the body’s procol- langenase system into a specific protease, quickly and safely removes the dead tissue from burns.30 Drug Addiction The xeronine link to treat ing drug addiction is based on the notion that flooding t he brain with extra xeronine can reverse the neurochemical basis for addiction. This natural alkaloid is thought to normalize brain receptors which subsequent ly results in the cessation of physiological dependence on a certain chemical like nicotine.3 1 The potential of Hawaiin noni as a natural stimulat or for t he production of xeronine may have profound implications in treating various types of addictions. Complementary Agents of Noni
PrimaryApplications of Noni
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=570) Promilin Fenugreek Extract - Supports Healthy Blood Sugar Levels
Date:
June 28, 2005 10:44 AM
.. Your body’s ability to manage blood sugar may well be the single most crucial factor affecting your health and longevity, and the one most affected by diet and lifestyle. But today’s high-glycemic carbs and sugar-laden foods — combined with lack of exercise — are creating a serious challenge to your body’s intricate glucose/insulin regulatory system. The resulting cellular stress and deterioration have serious repercussions for both your mind and body. To promote optimal wellness through healthy sugar metabolism, Source Naturals formulated PROMILIN™ FENUGREEK EXTRACT, a potent extract from the highly valued herb fenugreek, into an advanced nutritional supplement designed to assist insulin production and support healthy glucose levels. As a complement to your diet, Source Naturals PROMILIN™ FENUGREEK EXTRACT is an excellent strategy to improve blood sugar levels, and consequently, quality of life. The basis of Source Naturals PROMILIN™ FENUGREEK EXTRACT is fenugreek (Trigonella foenum-graecum), a respected culinary and medicinal herb used throughout history. One of the formula’s fenugreek extracts is rich in galactomannan, a mucilaginous fiber that may benefit the bowel. The other extract is Promilin, a patent-pending complex of bioactive amino acids standardized to contain 20% 4-hydroxyisoLeucine. This extraordinary amino acid derivative assists the pancreas in production of insulin. Several studies with animals and with human cell cultures demonstrate this extract’s positive effect on reducing post-meal glucose levels — with little or no increase in blood insulin concentrations — a clear indicator of improved insulin sensitivity. Sports Nutrition and Blood Sugar Athletic energy and endurance depend on the ability of muscles to recover from exercise. Because PROMILIN promotes utilization of glucose and insulin by the the body’s muscle cells, “weekend warriors” will feel less fatigue on Monday morning. In a clinical study, PROMILIN increased glycogen re-synthesis by 63% over carbohydrate alone. This is the rate at which post-exercise muscle glycogen (energy) is restored. PROMILIN may also play a role in weight management because it helps your body metabolize carbohydrates more efficiently. And the less time glucose spends in your bloodstream, the less chance it will be converted into fat. By supporting glucose metabolism, Source Naturals PROMILIN™ FENUGREEK EXTRACT may help protect against a harmful process called glycation, where excess glucose reacts with amino acids to form crosslinked sugardamaged proteins that damage the linings of blood vessels, the lens of the eye, and the myelin sheath that insulates brain cells.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=513) GARLIC AS AN ANTIOXIDANT
Date:
June 25, 2005 10:20 AM
GARLIC AS AN ANTIOXIDANT The term “antioxidant” has become a buzz word over the last decade. Defending ourselves against a wide array of chemicals, heavy metals, pollutants, radiation and poor nutrition has become a vital area of scientific focus and research. Oxidizing agents or free radicals attack our bodies constantly and have the potential to damage our cells, which compresses human tissue. Substances which have been found to help protect us from the cellular damage caused by free radicals include vitamin C, bioflavonoids, vitamin E, vitamin A, beta carotene and selenium to name a few. Garlic is not usually found on standard antioxidant lists and probably should be. Garlic has an abundance of sulfhydryl which is an excellent antioxidant. It’s important to know that raw garlic did not demonstrate this ability. In fact, raw garlic actually has some oxidant action, which is not desireable. Garlic can also help to lessen free radical damage because it has the ability to protect against radiation. In this regard, it may significantly decrease our risk of developing certain degenerative diseases such as cancer and premature aging. In addition, anyone undergoing radiation or chemotherapy should supplement their diet with garlic. “Based on a number of studies conducted by research teams from throughout the world, scientists have concluded that part of the preventive effect of garlic against cancer is due to protection against free radical damage. But that protection extended beyond the mere ability to protect against disease. The ability of garlic to protect against free radical damage may have yet another important benefit to cancer victims: it can, according to several published articles, protect against the damage that results from radiation treatment and chemotherapy commonly given to many cancer patients.” 44 Garlic also contains a number of amino acids which are required for the formation of an enzymatic antidote to free radical pathology which is created by cigarette smoke and other pollutants. Cysteine, glutamine, isoLeucine and methionine found in garlic help to protect the cells from free radical damage. Garlic works as an antioxidant the same way that onions, and green chilies do. In his book The Miracle of Garlic, Paavo Airola states: “An Indian study showed that garlic exhibited a high antiox idant property as determined by the peroxide values of the products by the swift stability test. Garlic restrained the development of all characteristic indexes of rancidity (acids, peroxides, iodine no. etc.). Garlic retained its antioxidant property for a half year after harvesting.”45 Because our food, air, water and environments are heavily contaminated with pollutants of all kind including food additives, preservatives, artificial colorings, flavorings, sweeteners, chemical fertilizers, etc., garlic should become a permanent addition to our nutritional array of supplements.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=440) Muscle Mass - Reach Your Maximum Muscle Potential 
Date:
June 04, 2005 09:49 AM
The serious athletes of today know how much it takes to fulfill their competitive goals: careful training, a strong will, and also the right kind of nutrition. Sports science now makes available key nutrients which help assure that strenuous workout regimes will show results. Results that are both nutritionally sound and dramatically visible, without the need for dangerous steroids or chemicals. MUSCLE MASS™ is such a state-of-the-art sports science formula. THE PURPOSE OF MUSCLE MASS ™ is to help translate distant goals for greater strength and power into quicker, awesome reality. It is the premier formula combining all essential nutrients known to maximize muscle development and optimize strength.
In sum, all these balanced, cutting-edge factors combine to assist you in meeting the challenges you’ve set for your body. Power, endurance, strength, tone, and the winner’s circle are now closer.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=177) | ||||||||||||
Leucine is one of 3 amino acids that increases muscle mass and will also help you to recover after exercise. Leucine supplies the body with energy and regulate blood sugar. Being an essential amino acids, it cannot be synthesized by the body and thus you need to get it from food or supplements. But Can L-Leucine help glucose metabolism and insulin function?
Introduction
Essential amino acids are amino acids that cannot be synthesized by the body and must be ingested from plant and animal sources. There are ten essential amino acids needed by humans plus an extra two essential amino acids needed by infants. For athletes, a large amount of essential amino acids of all types is needed to help repair, grow and maintain muscle. This iis where 3 essential amino acids come into play .These are Leucine, isoLeucine and valine.
