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Shiitake mushrooms are a powerful medicinal superfood Darrell Miller 5/9/19
Immune Renew Fact Sheet Darrell Miller 12/7/05
Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet Darrell Miller 12/7/05
PeakImmune4 Darrell Miller 11/23/05
Preventing Chronic Health Problems with AHCC Darrell Miller 10/26/05
Mushroom Immune Defense - Scientific Immunity Formula Darrell Miller 6/4/05
CAT’S CLAW DEFENSE COMPLEX - Health Secrets from the Rainforest Darrell Miller 6/1/05
Re: AHCC Complexe, Plus, and With Biopreine Darrell Miller 5/31/05
AHCC and its antifungal and antibacterial activity ... Darrell Miller 5/25/05



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Shiitake mushrooms are a powerful medicinal superfood
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Date: May 09, 2019 02:09 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Shiitake mushrooms are a powerful medicinal superfood





A new study has found that adding fermented shiitake mushroom to rice bran is effective in inhibiting the growth of Salmonella typhimurium. The study was conducted on mouse organs and it was published in the journal BMC Complementary and Alternative Medicine. This formulation has been hailed as a new antimicrobial food-compatible formulation. The study was conducted on murine macrophage cells and in mice. Before this, it was known that the bioactive compounds in rice brans and in shiitake mushrooms have a lot of potential health benefits in mice, cells, and rodents. When the mycelia cells were compared against non-fermented ones, it was found that the bioactive compounds present in the fermented shiitake mushrooms could not be found in the ones that had not fermented. Further findings showed that the pathogen, Salmonella, was inhibited in infected macrophage cells and in organs in the mouse such as the cecum, mesenteric lymph node, spleen, and the liver. Another finding was that there was increased secretion of the bacteria in the feces in mouse. Overall, this findings show that fermented shiitake mushrooms with rice brans can be used as an antibiotic and antimicrobial food.

Key Takeaways:

  • To carry out the study a team of researchers from Korea and the US tried to understand the effect of shiitake mushroom with rice bran on macrophage cells.
  • The component produced in rice plants are bioactive rice brans and hulls while that produced by mushrooms are bioactive polysaccharides and other compounds.
  • When mushroom mycelia that was fermenting with rice bran cells were inspected it was found that they have bioactive compounds that are absent in the non-fermenting mycelia.

"A study published in the journal BMC Complementary and Alternative Medicine found that a formulation of fermented shiitake mushroom with added rice bran can inhibit the growth of Salmonella typhimurium in infected mouse organs."

Read more: https://www.naturalnews.com/2019-04-16-shiitake-mushrooms-are-a-powerful-medicinal-superfood.html

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Immune Renew Fact Sheet
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Date: December 07, 2005 01:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Immune Renew Fact Sheet

Immune Renew Fact Sheet Neil E. Levin, CCN, DANLA 02/10/05

LIKELY USERS: Everyone seeking a healthy immune system; People on low carb diets or non-whole grain diets that are lacking dietary beta-glucans

KEY INGREDIENTS: Astragalus Root Extract Powder 70% polysaccharides (200 mg). Proprietary blend of 8 organically grown “medicinal mushrooms” (200 mg)

MAIN PRODUCT FEATURES: Vegetarian formula. Polysaccharides in these US-grown mushrooms grown on organic brown rice include 1,3 Beta-glucans and terpenoids. Beta-glucans may stimulate the immune system in different ways. Triterpenoids may act as mild anticoagulants. Each mushroom may have a different effect; for example, one may stimulate T-cells and another Natural Killer cells, aiding in immune defense. Mushrooms have reported beneficial effects on liver health and promoting normal cell growth.

ADDITIONAL PRODUCT INFORMATION: Some extracts from these kinds of mushrooms have been used medicinally in Japan and China. The mushrooms include Turkey Tail, Sun Mushrooms, Maitake, Cordyceps, Phellinus, Lion’s Mane, Reishi and Shiitake. The astragalus extract also contains naturally occurring astragalosides. Mushrooms may help maintain normal cholesterol and triglyceride levels

SERVING SIZE & HOW TO TAKE IT: For everyday use take one or two caps per day, either with meals or on an empty stomach.

COMPLEMENTARY PRODUCTS: Vitamin C to break down beta-glucan structures for better absorption, Inositol Hexaphosphate (IP-6), I3C, Pometrol, mixed carotenoids and antioxidants

CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. Do not take with AIDS drugs or if you have an autoimmune disease. Use with caution if using anticoagulants or blood pressure medication, as these mushrooms may have mildly synergistic effects to those drugs. Do not use if you have mold or mushroom allergies (or any sensitivities to mushrooms, cheese, etc.), which can potentially result in hives, rashes, breathing difficulties (including dry mouth or throat), stomach distress, diarrhea, or any other unusual side effect.

This information is based on my own knowledge and these references, but should not be used as diagnosis, prescription or as specific product claims.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

1. Hobbs C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995
2. Wasser SP, Weis AL. Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: a modern perspective. Crit Rev Immunol. 1999;19(1):65-96.
3. Wasser SP. Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl Microbiol Biotechnol. 2002 Nov;60(3):258-74. Epub 2002 Sep 10.
4. Nanba H, Hamaguchi AM, Kuroda H. The chemical structure of an antitumor polysaccharide in fruit bodies of Grifola frondosa (maitake). Chem Pharm Bull 1987;35:1162–8.
5. Yamada Y, Nanba H, Kuroda H. Antitumor effect of orally administered extracts from fruit body of Grifola frondosa (maitake). Chemotherapy 1990;38:790–6.
6. Nanba H. Immunostimulant activity in vivo and anti-HIV activity in vitro of 3 branched b-1–6-glucans extracted from maitake mushrooms (Grifola frondosa). VIII International Conference on AIDS, Amsterdam, 1992 [abstract].
7. Kubo K, Nanba H. Anti-hyperliposis effect of maitake fruit body (Grifola frondosa). I. Biol Pharm Bull 1997;20:781–5.
8. Adachi K, Nanba H, Otsuka M, Kuroda H. Blood pressure lowering activity present in the fruit body of Grifola frondosa (maitake). Chem Pharm Bull 1988;36:1000–6.
9. Jones K. Shiitake: A major medicinal mushroom. Alt Compl Ther 1998;4:53–9 [review].
10. Taguchi I. Clinical efficacy of lentinan on patients with stomach cancer: End point results of a four-year follow-up survey. Cancer Detect Prevent Suppl 1987;1:333–49.
11. Matsuoka H, Seo Y, Wakasugi H, et al. Lentinan potentiates immunity and prolongs survival time of some patients. Anticancer Res 1997;17:2751–6.
12. Guangwen Y, Jianbin Y, Dongqin L, et al. Immunomodulatory and therapeutic effects of lentinan in treating condyloma acuminata. CJIM 1999;5:190–2.
13. Jones K. Reishi mushroom: Ancient medicine in modern times. Alt Compl Ther 1998;4:256–66 [review].
14. Kammatsuse K, Kajiware N, Hayashi K. Studies on Ganoderma lucidum: I. Efficacy against hypertension and side effects. Yakugaku Zasshi 1985;105:531–3.
15. Jin H, Zhang G, Cao X, et al. Treatment of hypertension by ling zhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Nimmi H, Xiu RJ, Sawada T, Zheng C. (eds). Microcirculatory Approach to Asian Traditional Medicine. New York: Elsevier Science, 1996, 131–8.
16. Suzuki H, et al. Immunopotentiating Substances in Lentinus edodes Mycelial Extract(LEM)-- Activation of Macrophage and Proliferation of Bone Marrow Cell. Nippon Shokakibyo Gakkai Zasshi. Jul1988;85(7): 1430.
17. Suzuki H, et al. Inhibition of the Infectivity and Cytopathic Effect of Human Immunodeficiency Virus by Water-soluble Lignin in an Extract of the Culture Medium of Lentinus edodes Mycelia (LEM). Biochem Biophys Res Commun. Apr1989;160(1):367-73.
18. Gordon M, et al. A Placebo-controlled Trial of the Immune Modulator, Lentinan, In HIV-positive Patients: A Phase I/II Trial. J Med. 1998;29(5-6):305-30.
19. Li JF, et al. Study on the Enhancing Effect of Polyporus Polysaccharide, Mycobacterium Polysaccharide and Lentinan on Lymphokine-activated Killer Cell Activity in vitro. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih. Apr1996;16(4):224-26.
20. Li KR, et al. Anti-atherosclerotic Properties of Higher Mushrooms (a Clinico-experimental Investigation. Vopr Pitan. Jan1989;1:16-19.
21. Shouji N, et al. Anticaries Effect of a Component From Shiitake (An Edible Mushroom). Caries Res. Feb2000;34(1):94-98.
22. Levy AM. Eosinophilia and Gastrointestinal Symptoms After Ingestion of Shiitake Mushrooms. J Allergy Clin Immunol. May1998;101(5):613-20.
23. Zjawiony JK. Biologically active compounds from Aphyllophorales (polypore) fungi. J Nat Prod. 2004 Feb;67(2):300-10.
24. Oliva D. Cellular and physiological effects of Ganoderma lucidum (Reishi). Mini Rev Med Chem. 2004 Oct;4(8):873-9.
25. Ooi VE, Liu F. Immunomodulation and anti-cancer activity of polysaccharide-protein complexes. Curr Med Chem. 2000 Jul;7(7):715-29.
26. Borchers AT, Stern JS, Hackman RM, Keen CL, Gershwin ME. Mushrooms, tumors, and immunity. Proc Soc Exp Biol Med. 1999 Sep;221(4):281-93.
27. Mau JL, Lin HC, Chen CC. Antioxidant properties of several medicinal mushrooms. J Agric Food Chem. 2002 Oct 9;50(21):6072-7.
28. Hirasawa M, Shouji N, Neta T, Fukushima K, Takada K. Three kinds of antibacterial substances from Lentinus edodes (Berk.) Sing. (Shiitake, an edible mushroom). Int J Antimicrob Agents. 1999 Feb;11(2):151-7.
29. Rajewska J, Balasinska B. Biologically active compounds of edible mushrooms and their beneficial impact on health. Postepy Hig Med Dosw (Online). 2004 Oct 5;58:352-7.
30. Chang R. Functional properties of edible mushrooms. Nutr Rev. 1996 Nov;54(11 Pt 2):S91-3.
31. Lin ZB, Zhang HN. Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms. Acta Pharmacol Sin. 2004 Nov;25(11):1387-95. PMID: 15525457
32. Cheung NK, Modak S, Vickers A, Knuckles B. Orally administered beta-glucans enhance anti-tumor effects of monoclonal antibodies. Cancer Immunol Immunother. 2002 Nov;51(10):557-64. Epub 2002 Sep 20. PMID: 12384807
33. Shamtsyan M, Konusova V, Maksimova Y, Goloshchev A, Panchenko A, Simbirtsev A, Petrishchev N, Denisova N. Immunomodulating and anti-tumor action of extracts of several mushrooms. J Biotechnol. 2004 Sep 30;113(1-3):77-83. PMID: 15380649
34. Zhang YD, Shen JP, Zhu SH, Huang DK, Ding Y, Zhang XL. Effects of astragalus (ASI, SK) on experimental liver injury Yao Xue Xue Bao. 1992;27(6):401-6. Chinese. PMID: 1442065
35. Sheng BW, Chen XF, Zhao J, He DL, Nan XY. Astragalus membranaceus reduces free radical-mediated injury to renal tubules in rabbits receiving high-energy shock waves. Chin Med J (Engl). 2005 Jan;118(1):43-9. PMID: 15642225
36. Yesilada E, Bedir E, Calis I, Takaishi Y, Ohmoto Y. Effects of triterpene saponins from Astragalus species on in vitro cytokine release. J Ethnopharmacol. 2005 Jan 4;96(1-2):71-7. PMID: 15588652
37. Li C, Cao L, Zeng Q. Astragalus prevents diabetic rats from developing cardiomyopathy by downregulating angiotensin II type2 receptors' expression. J Huazhong Univ Sci Technolog Med Sci. 2004;24(4):379-84. PMID: 15587404
38. Wang SH, Wang WJ, Wang XF, Chen W. [Effect of Astragalus polysaccharides and berberine on carbohydrate metabolism and cell differentiation in 3T3-L1 adipocytes]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Oct;24(10):926-8. Chinese. PMID: 15553830
39. Shao BM, Dai H, Xu W, Lin ZB, Gao XM. Immune receptors for polysaccharides from Ganoderma lucidum. Biochem Biophys Res Commun. 2004 Oct 8;323(1):133-41. PMID: 15351712
40. Mao SP, Cheng KL, Zhou YF. [Modulatory effect of Astragalus membranaceus on Th1/Th2 cytokine in patients with herpes simplex keratitis]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Feb;24(2):121-3. Chinese. PMID: 15015443
41. Guo FC, Williams BA, Kwakkel RP, Li HS, Li XP, Luo JY, Li WK, Verstegen MW. Effects of mushroom and herb polysaccharides, as alternatives for an antibiotic, on the cecal microbial ecosystem in broiler chickens. Poult Sci. 2004 Feb;83(2):175-82.



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Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet
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Date: December 07, 2005 12:16 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet

Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet Neil E. Levin, CCN, DANLA 02/10/05

LIKELY USERS: People with exposure to toxins that stimulate liver activity; People with exposure to infections that may have damaged liver tissue

KEY INGREDIENT (S): Milk Thistle extract (Silymarin), Glutathione, NAC, Bupleurum extract, Grape Seed Extract, Dandelion Root extract, Artichoke Leaf, Schisandra and about a dozen additional herbs, along with synergistic ingredients

MAIN PRODUCT FEATURES: This formula was developed by a physician based on his clinical experience.

Artichoke leaf has antioxidant properties and restores healthy growth to liver cells.

Bupleurum may promote normal cell growth, immune function and is a staple of Chinese liver formulas. Dandelion Root may serve as a natural down-regulator of inflammatory chemicals in the body. NAC supports liver Glutathionestores (antioxidant, detoxifier, heavy metal chelator). Schisandra protects liver cells from toxins and may help to regenerate damaged cells. Milk thistle’s antioxidant Silymarin improves liver function tests and protects liver cells against oxidative damage. It also protects liver cells by blocking and removing toxins from the liver. Silymarin aids in regenerating injured liver cells and blocks fibrosis.

OTHER IMPORTANT ISSUES: Samuel Verghese, M.D. (AM), Ph.D., BCIA-EEG, DAAPM, holds a degree in Alternative Medicine and specializes in Nutritional, Ayurvedic and other Alternative Health Solutions. He is certified as a BCIA-EEG Associate Fellow.

AMOUNT TO USE: Three or more capsules a day, preferably with meals.

COMPLEMENTARY PRODUCTS: Antioxidants (supports liver detoxification), Alpha Lipoic Acid, EGCg Green Tea Extract, Astragalus, medicinal mushrooms (shiitake, reishi), SAM-e (may improve bile flow and promotes methylation to detoxify chemicals), TMG, lecithin, thymus glandular extract, Cordyceps.

AVOID: acetaminophen, alcohol, iron supplements (also red meat, fortified flour)

CAUTIONS: This formula should not be used by pregnant women, nursing mothers children or those with liver problems unless recommended under the supervision of a healthcare professional. Please notify your physician about your supplement use if you are using any drugs! Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

1. Salmi HA, Sarna S. Effect of silymarin on chemical, functional and morphological alterations of the liver. A double-blind controlled study. Scand J Gastroenterol 1982;17:517–21.
2. Feher J, Deak G, Muzes G, et al. Liver-protective action of silymarin therapy in chronic alcoholic liver diseases. Orv Hetil 1989;130:2723–7 [in Hungarian].
3. Muzes G, Deak G, Lang I, et al. Effect of silymarin (Legalon) therapy on the antioxidant defense mechanism and lipid peroxidation in alcoholic liver disease (double blind protocol.) Orv Hetil 1990:131:863–6 [in Hungarian].
4. Velussi M, Cernigoi AM, De Monte A, et al. Long-term (12 months) treatment with an anti-oxidant drug (silymarin) is effective on hyperinsulinemia, exogenous insulin need and malondialdehyde levels in cirrhotic diabetic patients. J Hepatol 1997;26:871–9.
5. Lieber CS. Nutrition in liver disorders. In: Shils ME, Olson JA, Shike M, Ross AC (eds). Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins, 1999, 1179–80.
6. Rodriguez-Moreno F, Gonzalez-Reimers E, Santolaria-Fernandez F, et al. Zinc, copper, manganese, and iron in chronic alcoholic liver disease. Alcohol 1997;14:39–44.
7. Gibbs K, Walshe JM. Studies with radioactive copper (64 Cu and 67 Cu); the incorporation of radioactive copper into caeruloplasmin in Wilson’s disease and in primary biliary cirrhosis. Clin Sci 1971;41:189–202.
8. Lieber CS. Nutrition in liver disorders. In: Shils ME, Olson JA, Shike M, Ross AC (eds). Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins, 1999:1179–80.
9. Halsted CH. Alcohol: medical and nutritional effects. In Ziegler EE, Filer LJ (eds). Present Knowledge in Nutrition, 7th ed. ILSI Press, Washington, DC, 1996, 553.
10. Blum AL, Doelle W, Kortum K, et al. Treatment of acute viral hepatitis with (+)-cyanidanol-3. Lancet 1977;2:1153–5.
11. Suzuki H, Yamamoto S, Hirayama C, et al. Cianidanol therapy for HBs-antigen-positive chronic hepatitis: a multicentre, double-blind study. Liver 1986;6:35–44.
12. Tang W, Eisenbrand G. Chinese Drugs of Plant Origin. Berlin: Springer Verlag, 1992. (Astragalus)
13. Hobbs, C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995, 96–107.
14. Harada T, Kanetaka T, Suzuki H, Suzuki K. Therapeutic effect of LEM (extract of cultured Lentinus edodes Mycelia) against HBeAg-positive chronic hepatitis B. Gastroenterol Int 1988;1(suppl 1):abstract 719. 15. Kelly GS. Clinical applications of N-acetylcysteine. Altern Med Rev. Apr1998;3(2):114-27.
16. Montanini S, et al. Use of acetylcysteine as the life-saving antidote in Amanita phalloides (death cap) poisoning. Case report on 11 patients. Arzneimittelforschung. Dec1999;49(12):1044-7.
17. Buckley NA, et al. Oral or intravenous N-acetylcysteine: which is the treatment of choice for acetaminophen (paracetamol) poisoning? J Toxicol Clin Toxicol. 1999;37(6):759-67. 18. Girardi G, Elias MM. Effectiveness of N-acetylcysteine in protecting against mercuric chloride-induced nephrotoxicity. Toxicology. Apr1991;67(2):155-64.
19. Berkson MB. Alpha-Lipoic Acid (Thioctic Acid): My Experience With This Outstanding Therapeutic Agent. Journal of Orthomolecular Medicine. 1998;13(1):44-48.
20. Breithaupt-Grogler K, et al. Dose-proportionality of oral thioctic acid--coincidence of assessments via pooled plasma and individual data. Eur J Pharm Sci. Apr1999;8(1):57-65.
21. Gebhardt R. Antioxidative and Protective Properties of Extracts from Leaves of the Artichoke (Cynara scolymus L.) Against Hydroperoxide-induced Oxidative Stress in Cultured Rat Hepatocytes. Toxicol Appl Pharmacol. Jun1997;144(2):279-86.
22. Adzet T, et al. Hepatoprotective Activity of Polyphenolic Compounds From Cynara scolymus Against CCl4 Toxicity in Isolated Rat Hepatocytes. J Nat Prod. Jul1987;50(4):612-17.
23. Gebhardt R. Antioxidative and protective properties of extracts from leaves of the artichoke (Cynara scolymus L.) against hydroperoxide-induced oxidative stress in cultured rat hepatocytes. Toxicol Appl Pharmacol. Jun1997;144(2):279-86.
24. Khadzhai I, et al. Effect of Artichoke Extracts on the Liver. Farmakol Toksikol. Nov1971;34(6):685-87.
25. Newall CA, et al. Herbal Medicine: A Guide for Health-Care Professionals. Cambridge: Pharmaceutical Press; 1996:36-37.
27. Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press;1996:96-97.
28. Bradley PR, ed. British Herbal Compendium. Vol.1. Bournemouth: British Herbal Medicine Association;1992:73-74.
29. Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press;1996:96-97.



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PeakImmune4
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Date: November 23, 2005 06:15 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: PeakImmune4

New from:

Daiwa Health Developement

PeakImmune4™

Clinically Shown to Triple Natural Killer (NK) Cell Activity

  • A dietary supplement containing the same immune complex previously sold to a veryloyal customer base.

  • May help safely and naturally to modulate your immune system to perform its roleagainst foreign invaders.

  • Based on a patented and proprietary Rice Bran Arabinoxylan Compound, clinicallyshown to triple the activity of Natural Killer cells—white blood cells that are consid-ered the body’s first line of defense.

  • Also doubles immune system T cell count, increases B cell count, and boosts chemi-cal messengers critical to intercellular communication for fighting pathogens.

  • An immune modulator, which does not result in hyporesponsiveness or hyperrespon-siveness of the immune system; it therefore does not lose effectiveness over time, norcause the immune system to attack itself.

  • No need to cycle on or off of PeakImmune4 as with some other immune products.

  • Efficacy and safety shown in clinical studies and in practice by tens of thousands ofusers worldwide.

    4 capsules contain:

    Proprietary RBAC* Blend1000 mg
    Rice BranHyphomycetes Mycelia Extract (from Shiitake Mushroom)

    *RBAC (Rice Bran Arabinoxylan Compound)

    Suggested use: As a dietary supplement, take four (4) capsules before or after a meal. Forthe best results, the following two-step program is recommended:

    1st step:Take 4 capsules 3 times per day for 4 weeks.

    2nd step:After 4 weeks, reduce dosage to the maintenance level of 4 capsules daily.

    PeakImmune4 is a trademark of Daiwa Health Development, Inc.



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    Preventing Chronic Health Problems with AHCC
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    Date: October 26, 2005 05:57 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Preventing Chronic Health Problems with AHCC

    Preventing Chronic Health Problems with AHCC

    In a country supposedly as healthy as ours, an estimated 175 million people suffer from one form of chronic imbalance or another. This can take the form of obesity, which is the second leading cause of preventable death in the United States, second only to cigarette smoking; challenges to heart health, blood pressure, blood glucose levels, joint and cell health ,to name just a few.

    In fact ,treating chronic health problems is what modern medicine has become .Sure, there are still many acute illnesses treated by modern medicine; but for the most part, we are fortunate enough to have long life spans and the health issues that go along with it. Therefore it is important to make sure that out immune systems are up to the task. That is where AHCC should become part of our daily lives.

    AHCC is an nutritional supplement that was developed and is manufactured solely in Japan under strict practices. It is a hybridized extract of medicinal mushrooms where the active ingredient is an oligosaccharide made from the Mycelia of several species of mushrooms, grown in rice bran.

    AHCC and Cell Senescence

    Every few years, a new buzz word comes along in medical circles. The latest one to be used both in a positive and negative fashion is senescence. For example, if an unhealthy cell can be artificially made to senesce, or grow old, then it will die sooner. If senescence of healthy cells can be delayed, that is an amazing achievement.

    AHCC is the first nutritional supplement that shows principles of being able to promote certain cells in the immune system that keep us young and healthy, thus delaying immunosenesnscence.

    AHCC and the Immune System

    In order to get a full appreciation of how important taking AHCC on a daily bases is, one needs to understand the intimate role the immune system plays in our daily lives. It is responsible for riding our bodies of the unhealthy cells that are produced every day. The immune system protects us from the polluted air we breathe, the chemicaalized foods we eat, and most importantly, from the stress we bring upon ourselves just by the very nature of the way we live our lives. Our bodies were made for flight or fight capability; but never in history have we been in that mode on a daily basis. Our immune systems are under constant assault and it is up to you to take care of it even though you may not even be aware that it is there. We tend to only to think of our immune system when it is not working-when suffer mild or severe health challenges.

    Without getting into too much detail, our immune system is a complex series of cells that all communicate with each other and must be balanced correctly in order for us to stay healthy. AHCC is able to encourage the helpful cells such as the natural killer (NK) cells while suppressing the ones that foster problems.

    I am in clinical practice on a daily basis and use AHCC in almost every one of my patients. It is very versatile because of its effects on the immune system.

    A Company Committed to Excellence

    If everything I just told you wasn’t enough to convince you that AHCC should become part of your daily armamentarium, then here’s more fuel. AHCC is produced by a chemical company that is committed to excellence in manufacturing and most importantly in research. They have supported research at hospitals around the world, including local ones such as Columbia University, Harvard University and the University of California.

    In fact, I just returned from a trip to Sapporo, Japan where the product is made and where each year, a team of scientists and medical professionals gather to discuss the latest research on AHCC, GCP, and oliganol-all products made by the same company. This was the 13th annual symposium and was attended by close to 1000 professionals.

    It is remarkable to me that this company is able to produce such well-documented research while still being a nutritional supplement company, which shows it can be done. To me, this is the sign of a nutritional supplement worth recommending. If it does what it says it is supposed to do and has research to support those claims, than that is something you want in your daily diet.

    So, even though you may never have given your immune system a second thought, you really should; and the best way to help it out is by taking AHCC on a daily basis, just like I do. I recommend 500 mg per day in the summer months and 1500 per day in the winter months as a simple preventive. Stay healthy!

    About the Author

    Fred Pescator, M.D., a traditionally trained physician practicing nutritional medicine, is President of the AHCC Research Association. He is the author of The Hamptons’ Diet, Thin For Good and Feed Your Kids Well. Dr.Pescator lectures around the world, and has been featured on such shows as The View, The Today Show, Deborah Norville, The O’ Reilly Factor, and Extra. Recent interviews include Woman’s Health and Fitness, Let’s Live, the New York Times, the Wall Street Journal, Fortune and more. He is also the author of numerous papers and magazine articals. Dr.Pescator is actively involved in clinical research , and is instrumental in developing and clinically testing many of the leading nutritional products. He is the President-Elect of the International and American Association of Clinical Nutritionists and a member of the National Association of Physician Broadcasters.

    The above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider. The information in this article has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

    AHCC 49% OFF




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    Mushroom Immune Defense - Scientific Immunity Formula
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    Date: June 04, 2005 10:08 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Mushroom Immune Defense - Scientific Immunity Formula

    Mushroom

    The immune system is a fascinating and complex group of cells and biochemical processes. Its many components work to protect you from environmental threats—but your immune system requires nutritional support to function optimally. Scientific research is proving that some of the most powerful immune-supportive nutrients are found in mushrooms. People who realize the critical importance of optimizing immune function should seriously consider adding an advanced mushroom complex to their daily regimen. No other mushroom formula offers the high-potency, broad-spectrum benefits of Source Naturals MUSHROOM IMMUNE DEFENSE. MUSHROOM IMMUNE DEFENSE features 16 of the best-studied species of health-supportive mushrooms, including shiitake, reishi, and maitake. These mushrooms contain compounds, including beta-glucans, glycoproteins and polysaccharides, that support a wide range of immune defenses: natural killer cell, T-cell and macrophage activity, and cytokine production. By combining a wide variety of mushrooms and fortifying them with extracts to ensure high potency, MUSHROOM IMMUNE DEFENSE offers a biochemically diverse formula that provides optimum immune assistance.

    How Do Mushrooms Work?

    Mushrooms are a treasure trove of bioactive compounds, but most of their immunomodulating activities have been attributed to polysaccharides (long-chain, simple sugars) and glycoproteins (polysaccharides naturally associated with proteins). These compounds activate a variety of immune responses.

    Broad-Range Protection

    MUSHROOM IMMUNE DEFENSE contains Mycelia (networks of fibrous filaments) and extracts from the widest variety of mushroom species available. Included are the following mushrooms, which have demonstrated the most evidence for immune defense. Shiitake (Lentinula edodes): Lentinan, the beta glucan from shiitake, has been studied more extensively than similar substances and may be one of the most effective immunomodulators. Numerous studies have shown its ability to stimulate natural killer cell, T-cell, and macrophage-dependent responses.

    Reishi (Ganoderma lucidum): Reishi’s polysaccharides may stimulate macrophages and enhance T-cell proliferation, according to in vitro studies.

    Maitake (Grifola frondosa): Maitake enhances the activities of natural killer cells, T-cells and macrophages, according to animal studies. MUSHROOM IMMUNE DEFENSE contains MaitakeGold 404™, a highly specialized maitake product, rich in beta-glucans, which is the only maitake betaglucan fraction endorsed by the world’s premier maitake researcher, Dr. Hiroaki Nanba, Ph.D. Turkey Tails (Trametes versicolor): These mushrooms have a long history of traditional use in Asia. One in vitro study suggests that its polysaccharides stimulate macrophages.

    Almond portabella (Agaricus blazei): This mushroom may stimulate the immune system by increasing T-cell activity, according to animal studies.

    Cordyceps (Cordyceps sinensis): Cordyceps came to international attention during National Games in China when, in one week, three women’s track and field world records were broken. The coach partially credited a cordyceps elixir. Cordyceps was found to augment antibody and other immune responses in one animal study, and a cordyceps polysaccharide was found to elevate cytokines in vitro.

    MUSHROOM IMMUNE DEFENSE contains 10 additional mushrooms, including enoke, oyster, Polyporus umbellatus, and Poria cocos. Vitamin C is added to enhance absorption and activity.

    Unparalleled Immune Support

    A focus on immune support can pay tremendous dividends for your entire life. If you are dedicated to good health, you want a powerful formula on your side. Source Naturals is proud to join forces with your natural foods retailer to bring you an unparalleled immune formula: MUSHROOM IMMUNE DEFENSE.

    References
    Kurashige S, et al. 1997. Immunopharmacol Immunotoxicol 1997 19(2):175-83. Wang S. Y. et al. 1994. Program and Abstracts of the ’94 International Symposium on Ganoderma Research. Beijing: Beijing Medical University. Wasser S. P. and Weis A. L. 1999a. Crit Rev Immunol, 19, 65-96.



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    CAT’S CLAW DEFENSE COMPLEX - Health Secrets from the Rainforest
    TopPreviousNext

    Date: June 01, 2005 09:59 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: CAT’S CLAW DEFENSE COMPLEX - Health Secrets from the Rainforest

    CAT’S CLAW DEFENSE COMPLEX

    Standard pharmaceutical drugs came into common use only around the turn of the century. Before that, herbal preparations were administered for health concerns. Today, in nearly every country in the world, herbs are used by health care practitioners as the focal point of health care. Only in the United States is the otherwise widespread use of herbs missing in mainstream culture. But now modern scientific investigation is confirming the benefits of herbal supplementation, which is paving the way for us to reclaim and implement herbs into our everyday lives.

    The primary need for preserving the rainforests

    Rain Forest Herbs

    Scientists’ knowledge of the varied rain forest flora is far from complete. The plants which have been thus far identified are so elaborate in molecular structure that it’s difficult to understand how these molecules function, let alone how to reproduce them. What is known is that the biodiversity of the rain forest yields numerous biologically active plant constituents which can have a profound influence on supporting the body through times of imbalance. Preserving the rain forest means preserving these precious herbs and the unique constituents contained within them.

    Cat’s Claw Defense Complex contains powerful rainforest herbs

    A Synergistic Blend

    Source Naturals CAT’S CLAW DEFENSE COMPLEX harnesses the power of some of the most complex botanicals on earth into a synergistic blend of defense-enhancing herbs, each with a unique set of compounds which complement the body’s natural physiology. Source Naturals CAT’S CLAW DEFENSE COMPLEX is the first step in the rediscovery of a long-standing herbal tradition. Source Naturals was the first full-line supplement company to introduce the herbal superstar, Cat’s Claw, and the first to offer it in a combination formula. CAT’S CLAW DEFENSE COMPLEX provides 2000 mg of Cat’s Claw per four tablets – more than many companies’ single ingredient Cat’s Claw products! It combines powerful rain forest herbs like Pau D’Arco and Western herbs such as Aloe Vera and St. John’s Wort with legendary Chinese herbs (Reishi Mushroom and Astragalus). Source Naturals Cat’s Claw Defense Complex also includes two categories of antioxidants for broad spectrum support.

    How we ensure quality and potency

    Cat’s Claw & Pau D’Arco – Peruvian Jungle Discoveries

    Cat’s Claw was discovered in the depths of the Peruvian Amazon jungle. Researchers have discovered that components extracted from the herb can bolster the body’s innate defenses, address discomforts associated with stress, and support intestinal health. Source Naturals uses only the highest quality Cat’s Claw inner bark – which is at least twenty years old, the amount of time it takes the bark to reach its peak biological activity– and uses a careful process to insure that harvesting the bark doesn’t weaken or destroy the plant. Like all of our herbs, each shipment of Cat’s Claw is also routinely inspected and tested by a trained herbalist to ensure maximum quality and potency. Pau D’Arco is also native to the South American rain forest and, like Cat’s Claw, has a high concentration of active constituents – a combination of anthraquinones and naphthoquinones, primarily lapachol – in the bark of the plant. Each daily dosage of CAT’S CLAW DEFENSE COMPLEX contains 100 mg of Pau D’Arco bark and 100 mg of concentrated Pau D’Arco bark extract for broad spectrum support.

    Herbs — Adaptogens for Balance

    Of the Chinese herbs, Siberian Ginseng is one of the best known adaptogens. Adaptogens have a balancing effect, helping us adapt to increased stress levels and other changes, like different altitudes or time zones. Thus, supplementation with Siberian Ginseng can help prevent stress-related health concerns. Schizandra, a small creeping vine with red berries, is a Chinese adaptogen which helps regulate the body’s functions and cleanse it of toxins.

    Herbs that energize the body and build resistance to impaired bodily function

    The trio of Chinese mushrooms – Reishi, Shiitake, and Maitake – has been used by Chinese herbalists for centuries, and provides the highest quality natural support for the body’s defenses. Modern science has revealed the true power behind Reishi, Shiitake, and Maitake: high levels of polysaccharides – long chain sugar macromolecules which are known for their protective and cleansing abilities. CAT’S CLAW DEFENSE COMPLEX utilizes only the Mycelia biomass of Reishi (200 mg), Shiitake (200 mg), and Maitake (150 mg) to ensure the highest level of activity. Astragalus is the premier tonic – or internal strengthener – of Chinese herbalism. In addition to helping energize the body, Astragalus also builds resistance to weakness and to impaired bodily function. Isatis is a cooling herb which has been shown to have a broad spectrum inhibitory action in in-vitro studies, and helps support normal liver function. Used for thousands of years, the aloe plant has been treasured for its varied uses both externally and internally. Aloe Vera juice is high in mucopolysaccharides, which have been found to have powerful protective capabilities. CAT’S CLAW DEFENSE COMPLEX provides 200 mg of aloe (200:1 concentration) extracted from the whole leaf of the plant.

    Why St. John’s Wort is powerful and useful

    It is generally agreed that hypericin and pseudohypericin, two bioflavonoids which are the active constituents in St. John’s Wort, probably act as monoamine oxidase (MAO) inhibitors, which current research has shown are powerful as internal cleansing agents. St. John’s Wort is particularly useful because of its ability to cross the Blood-Brain Barrier, through which many elements are unable to pass.

    The liver’s health is essential because of its responsibility for over 500 different functions

    Antioxidants and Plantioxidants – Supporting Complete Health

    Source Naturals CAT’S CLAW DEFENSE COMPLEX includes key liver-supporting antioxidants like Zinc, Beta Carotene, and Vitamin C – nutrients that help protect the liver from stress and pollution induced free radical damage. These three nutrients are also wellknown for their ability to help strengthen the body’s resistance and move through imbalances quickly. The liver is responsible for over 500 functions, including converting vitamins to their active forms, and processing and eliminating waste products from the body; therefore its health is vital. Plantioxidants™ is Source Naturals’ term for Plant-Derived Antioxidant Bioflavonoids. Though most people are only aware of the vitamin and mineral antioxidants, the latest scientific research has indicated that the plant kingdom may provide the most potent antioxidants in the world. Plants, trees, and citrus fruits all contain bioflavonoids (also called polyphenols) – a large group of restorative compounds with similar chemical structures which help protect the body from the ravages of oxidative damage due to free radicals. Some of the Plantioxidants included in CAT’S CLAW DEFENSE COMPLEX are: Quercetin, which helps inhibit the body’s sensitivity to dangerous particles in the air; Proanthodyn, which promotes tissue repair by helping to strengthen collagen and elastin, the two primary structural components in cartilage; Silymarin, which promotes liver-tissue regeneration and optimizes liver-cell function; Green Tea, a remarkably potent antioxidant; and Ginkgo, which is renowned for helping transport oxygen to the brain.

    The way to naturally bolster the body’s defenses

    A Holistic Natural Answer

    The natural world provides us with a seemingly endless supply of complex herbal compounds with unreplicable and unique constituents so varied and numerous that most doctors aren’t even aware of their existence. Source Naturals would like to change that with CAT’S CLAW DEFENSE COMPLEX – the natural way to bolster the body’s innate defenses. All the ingredients included are at optimal potencies, and in the forms best absorbed by the body. The result? The most powerful, holistic product available to help maintain the structure and function of the natural defenses – Source Naturals CAT’S CLAW DEFENSE COMPLEX.



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    TopPreviousNext

    Date: May 31, 2005 04:27 PM
    Author: Darrell Miller (dm@vitanetonline.com)

    AHCC

    The human immune system is the extraordinary biochemical network responsible for keeping us well. As our molecular interface with the environment, it has evolved complex interactions with the plant world. Mushrooms, which form one of the most primitive plant groups, have been valued for decades by progressive medical practitioners as immunopotentiators. Only recently, however, has science identified and tested the specific mushroom nutrients that augment natural defenses. AHCC® (active hexose correlated compound) is a proprietary mushroom compound. It is wellresearched in Japan for its immune-supportive properties, in particular the ability to increase natural killer cell and macrophage activity. Hundreds of Japanese hospitals and clinics recommend AHCC as part of an immune maintenance regimen, and its potent effects are so highly regarded that sales exceed $200 million dollars per year.

    AHCC ®: A Unique Compound

    AHCC, or “active hexose correlated compound,” is a rich source of polysaccharides (beta glucan 1,3 and activated hemicellulose) and glycoproteins, plus amino acids and minerals. It is produced by enzymatic modification of several types of medicinal mushrooms, including shiitake. AHCC is derived from organically cultivated mushroom Mycelia (the rich pre-mushroom stage, a network of fibrous filaments plus the medium it lives on and uses for fuel). The low molecular weight of AHCC makes it easier to absorb.

    Natural Killer Cell and Macrophage Activity

    Your trillions of cells are susceptible to damage by free radicals and toxins, so a healthy immune system uses its first line of defense—natural killer (NK) cells—to quickly identify and destroy threatening particles. The effectiveness of NK cells depends on their activity level, so boosting NK activity is a smart strategy for those committed to maintaining vibrant health and longevity. AHCC is a potent biological response modifier that may significantly increase activity of NK cells and macrophages, according to human and animal studies. Literally “large things that devour,” macrophages are white blood cells that engulf and aid in the removal of foreign particles.

    Cytokine Production

    Studies show AHCC also enhances production of cytokines, including interferons and interleukins. These intercellular chemical messengers trigger white blood cell production and activity. In one recent study, AHCC was shown to support normal basal levels of two cytokines, as well as NK activity. It is rare for a natural compound to have such a profound impact on strengthening the immune system.

    Liver Support

    Your liver is your body’s chemical manufacturing and detoxification factory. It must handle the full brunt of assault from environmental contaminants and pharmaceuticals. Stress further burdens this overworked organ. Human studies suggest AHCC supports healthy liver function.

    Your Source for Scientifically Advanced Nutrition

    Source Naturals AHCC is the original proprietary compound that is attracting worldwide attention. And with no adverse side effects reported in dozens of studies and abstracts, it is certainly a nutritional approach worth considering. At a time when our systems are challenged by an unprecedented array of toxins, research into the remarkable immune-supportive properties of the plant world is critical. Source Naturals is your connection to this research, dedicated to quickly bringing you the benefts of the latest emerging wellness strategies.
    © 2003 Source Naturals, Inc., P.O. Box 2118, Santa Cruz, CA 95063 Strategies for Wellnesss

  • The above information has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
  • References Uno, K. et al. Biother 2000 14(3) 303-309. Matsiu, Y. et al. J Hepatol 37 (2002) 78-86.

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    AHCC and its antifungal and antibacterial activity ...
    TopPreviousNext

    Date: May 25, 2005 11:19 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: AHCC and its antifungal and antibacterial activity ...

    AHCC and its antifungal and antibacterial activity

  • the area of the Mycelial colony was measured and the inhibition of fungal growth observed
  • A transparent ring around the paper disk (with bacteria) signifies antibacterial activity.
  • The bacteria tested:

    S. aureus, P. aeruginosa, P. fluorescens, Proteus vulgaris, Bacillus subtilis, B. cereus, B. megaterium, B. subtilis, Escherichia coli, Enterobacter aerogenes, Micrococcusluteus and Mycobacterium phei.

    Reference:

    1.A ribonuclease with antimicrobial, antimitogenic and antiproliferative activities from the edible mushroom Pleurotus sajor-caju Patrick H.K. Ngai, T.B. Ng* Department of Biochemistry, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China Received 23 June 2003; accepted 25 November 2003



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